Rams TE, Andriolo M, Feik D, Abel SN, McGivern TM, Slots J; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 474 (abstract no. Th.B.P.350).
University of Pennsylvania School of Dental Medicine, Philadelphia, PA, USA
OBJECTIVE: To document the predominant microflora of a rapidly destructive form of periodontitis that has been associated with HIV-infection. METHODS: The subgingival microbiota in 12 HIV-infected males with severe periodontitis and no history of recent systemic antibiotic therapy were examined. Also studied were 5 HIV-related periodontitis patients with a history of recent antibiotic therapy. Subgingival plaque specimens were collected with paper points from diseased and normal sites and transported in VMGA III. The microbial samples were plated on selective and enriched brucella blood agar and incubated in 85% N(2)-10% H(2)-5% CO(2), and in 10% CO(2). RESULTS: Actinomyces viscosus was the most frequent subgingival isolate in normal periodontal sites. Periodontitis sites revealed higher mean CFUs and % gram-negative anaerobic rods. Predominant species included Actinobacillus actinomycetemcomitans (mean % of flora in culture-positive patients = 10.6%), Wolinella spp. (8.1%), Peptostreptococcus micros (21.4%), Bacteroides intermedius (15.5%), Fusobacterium spp. (9.3%), and spirochetes (15.2% of microscopic count). Low levels of Candida spp. and enteric gram-negative rods were detected in the subgingival flora of approximately 50% of the patients studied. Patients with recent antibiotic therapy generally had significantly lower proportions of suspected periodontopathic species. CONCLUSION: These findings may facilitate clinical management of HIV-related periodontitis and demonstrate that the subgingival flora in HIV-infected persons may serve as a reservoir for pathogenic organisms.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Actinobacillus actinomycetemcomitans
- Dental Plaque
- Fusobacterium
- Gram-Negative Bacteria
- HIV Infections
- HIV Seropositivity
- Humans
- Male
- Periodontitis
- Spirochaetales
Other ID:
UI: 102178360
From Meeting Abstracts