Bibliographic Citation
| Document | For copies of Journal Articles, please contact the Publisher or your local public or university library and refer to the information in the Resource Relation field. For copies of other documents, please see the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or Document Availability. |
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| Title | COMPARISON OF SELECTED ACTINOBACILLUS SPECIES WITH A HEMOLYTIC VARIETY OF ACTINOBACILLUS FROM IRRADIATED SWINE |
| Creator/Author | Wetmore, P.W. ; Thiel, J.F. ; Herman, Y.F. ; Harr, J.R. |
| Publication Date | 1963 Nov 01 |
| OSTI Identifier | OSTI ID: 4057480 |
| Resource Type | Journal Article |
| Resource Relation | J. Infect. Diseases; Vol: 114 |
| Research Org | Walter Reed Army Medical Center, Washington, D.C. |
| Subject | BIOLOGY AND MEDICINE; ANIMALS; ANTIGENS; BACTERIA; BIOCHEMISTRY; BIOLOGY; BLOOD; DIFFUSION; DISEASES; GUINEA PIGS; HEMOLYSIS; IMMUNITY; INFECTIONS; INTESTINE; IRRADIATION; LETHAL DOSE; METABOLISM; MICE; MINERAL ACIDS; NITRATES; NITROUS ACID; NUCLEAR EXPLOSIONS; PSEUDOMONAS; RADIATION EFFECTS; SWINE; TISSUES; VARIATIONS |
| Description/Abstract | In studies on the effects of irradiation in swine, microorganisms with colonial characteristics of the genus Actinobacillus were isolated from the blood and/or synovial fluid of inflamed hocks of four adult pigs and one piglet. These cultures were hemolytic, and otherwise varied little physiologically from available strains of Actinobacillus lignle resii and A. equuli. Therefore, attempts were made to further characterize these organisms isolnted from swine blood and synovial fluid, and to examine their biological similarities to strains of A. equuli, A. lignieresii, and A. mallei. Four of the isolates were from the blood of adult swine killed by an atomic explosion and the fifth was from a lethally irradiated young pig. These isolates were serologically related to strains of A. equuli and A. lignieresii; the latter species comprised a serologically heterogeneous group with irtergrading antigenic properties. Although A. equuli and A. lignieresii are classified in the literature as separate species on the basis of the ability of the former but not the latter to produce nitrite from nitrate, this separate speciation could not be confirmed, and it is proposed that the taxonomic designation equuli be discortinued. Also, A. Mallei strains were very different from other Actinobacillus strains, and it is suggested that the species A. mallei be designated as Pseudomonas mallei. In virulence studies, the actinobacflli isolated from irradiated swine did not produce evident disease when 1 billion cells were injected intraperitoneally in guinea pigs, but 500 million cells injected irto mice caused 35% mortality in 24 hr. (BBB) |
| Language | English |
| Format | Pages: 186-94 |
| System Entry Date | 2001 Jun 03 |
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Last Updated: 02/08/2009