| US 7,328,054 B2 | ||
| Perfusion magnetic resonance imaging using encoded RF tagging pulses | ||
| Andrzej Jesmanowicz, Wauwatosa, Wis. (US) | ||
| Assigned to The MCW Research Foundation, Inc., Milwaukee, Wis. (US) | ||
| Filed on Apr. 09, 2003, as Appl. No. 10/410,710. | ||
| Prior Publication US 2004/0204643 A1, Oct. 14, 2004 | ||
| Int. Cl. A61B 5/05 (2006.01) | ||
| U.S. Cl. 600—410 [600/419; 600/407] | 12 Claims |
| 1. A method for producing a perfusion image with an MRI system, the steps comprising:
a) repeatedly applying an RF tagging pulse with the MRI system to spins flowing into an image slice and modulating the flip
angle of the RF tagging pulse in accordance with a tagging pattern over a modulation time period;
b) acquiring a series of time course MR image data sets by performing imaging pulse sequences with the MRI system over a time
period that includes the modulation time period;
c) reconstructing from the image data sets a corresponding set of time course images having voxel vectors which indicate the
variations in NMR signal at corresponding image slice voxels over the acquisition time period;
d) detecting perfusion by identifying voxel vectors having variations in NMR signal which correspond to the tagging pattern;
and
e) producing a perfusion image in which perfusion is indicated at the identified voxels.
|