BLASTP 2.2.17 [Aug-26-2007]
Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Schäffer, Alejandro A., L. Aravind, Thomas L. Madden,
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= PG0625
(486 letters)
Database: nr
5,470,121 sequences; 1,894,087,724 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34540488|ref|NP_904967.1| 4-hydroxybutyryl-CoA dehydrata... 983 0.0
gi|84028213|sp|P55792|HDVD_CLOAM Gamma-aminobutyrate metabo... 776 0.0
gi|58176904|pdb|1U8V|A Chain A, Crystal Structure Of 4-Hydr... 774 0.0
gi|126699959|ref|YP_001088856.1| gamma-aminobutyrate metabo... 763 0.0
gi|121534266|ref|ZP_01666090.1| Vinylacetyl-CoA delta-isome... 753 0.0
gi|150016969|ref|YP_001309223.1| Vinylacetyl-CoA Delta-isom... 751 0.0
gi|34763075|ref|ZP_00144047.1| 4-hydroxybutanoyl-CoA dehydr... 739 0.0
gi|153955634|ref|YP_001396399.1| AbfD [Clostridium kluyveri... 738 0.0
gi|121540557|ref|ZP_01672318.1| Vinylacetyl-CoA delta-isome... 653 0.0
gi|78043633|ref|YP_360148.1| gamma-aminobutyrate metabolism... 649 0.0
gi|154241790|ref|ZP_02023352.1| Vinylacetyl-CoA Delta-isome... 607 e-172
gi|78223420|ref|YP_385167.1| 4-hydroxyphenylacetate 3-hydro... 588 e-166
gi|118193755|gb|ABK76673.1| 4-hydroxybutyryl-CoA dehydratas... 582 e-164
gi|11497945|ref|NP_069169.1| 4-hydroxyphenylacetate-3-hydro... 582 e-164
gi|121535316|ref|ZP_01667129.1| Vinylacetyl-CoA delta-isome... 577 e-163
gi|149922906|ref|ZP_01911327.1| gamma-aminobutyrate metabol... 532 e-149
gi|15899454|ref|NP_344059.1| 4-hydroxybutyryl-CoA dehydrata... 450 e-125
gi|116750562|ref|YP_847249.1| 4-hydroxyphenylacetate 3-hydr... 446 e-123
gi|119871764|ref|YP_929771.1| Vinylacetyl-CoA delta-isomera... 439 e-121
gi|146304087|ref|YP_001191403.1| Vinylacetyl-CoA Delta-isom... 438 e-121
gi|18313522|ref|NP_560189.1| 4-hydroxyphenylacetate-3-hydro... 434 e-120
gi|156937388|ref|YP_001435184.1| Vinylacetyl-CoA Delta-isom... 431 e-119
gi|70607859|ref|YP_256729.1| gamma-aminobutyrate metabolism... 431 e-119
gi|15921962|ref|NP_377631.1| hypothetical 4-hydroxyphenylac... 431 e-119
gi|78044808|ref|YP_360550.1| 4-hydroxyphenylacetate 3-hydro... 429 e-118
gi|126460004|ref|YP_001056282.1| Vinylacetyl-CoA Delta-isom... 429 e-118
gi|85858564|ref|YP_460766.1| aromatic ring hydroxylase [Syn... 421 e-116
gi|147677557|ref|YP_001211772.1| aromatic ring hydroxylase ... 379 e-103
gi|147678105|ref|YP_001212320.1| aromatic ring hydroxylase ... 348 5e-94
gi|11498632|ref|NP_069860.1| 4-hydroxyphenylacetate-3-hydro... 348 7e-94
gi|116751349|ref|YP_848036.1| 4-hydroxyphenylacetate 3-hydr... 329 3e-88
gi|119505692|ref|ZP_01627762.1| 4-hydroxyphenylacetate 3-hy... 319 3e-85
gi|145588557|ref|YP_001155154.1| Vinylacetyl-CoA Delta-isom... 300 2e-79
gi|124267702|ref|YP_001021706.1| Vinylacetyl-CoA delta-isom... 297 1e-78
gi|149376166|ref|ZP_01893931.1| 4-hydroxyphenylacetate 3-hy... 288 6e-76
gi|89897478|ref|YP_520965.1| hypothetical protein DSY4732 [... 280 2e-73
gi|11498490|ref|NP_069718.1| 4-hydroxyphenylacetate-3-hydro... 269 3e-70
gi|126009177|ref|ZP_01709747.1| hypothetical protein Faci_0... 262 5e-68
gi|15920242|ref|NP_375911.1| hypothetical protein ST0063 [S... 250 1e-64
gi|70606878|ref|YP_255748.1| hydroxylase [Sulfolobus acidoc... 248 9e-64
gi|146303989|ref|YP_001191305.1| Vinylacetyl-CoA Delta-isom... 228 5e-58
gi|15899242|ref|NP_343847.1| 4-hydroxybutyryl-CoA dehydrata... 228 6e-58
gi|55980929|ref|YP_144226.1| 4-hydroxyphenylacetate-3-hydro... 154 1e-35
gi|46198902|ref|YP_004569.1| 4-hydroxyphenylacetate 3-monoo... 153 3e-35
gi|108804686|ref|YP_644623.1| 4-hydroxyphenylacetate 3-hydr... 142 4e-32
gi|111018781|ref|YP_701753.1| probable 4-hydroxyphenylaceti... 141 1e-31
gi|118477510|ref|YP_894661.1| 4-hydroxyphenylacetate-3-hydr... 136 3e-30
gi|42781214|ref|NP_978461.1| 4-hydroxyphenylacetate-3-hydro... 136 3e-30
gi|71281564|ref|YP_268775.1| 4-hydroxyphenylacetate-3-hydro... 134 2e-29
gi|56421569|ref|YP_148887.1| 4-hydroxyphenylacetate-3-hydro... 133 3e-29
gi|138896629|ref|YP_001127082.1| 4-hydroxyphenylacetate-3-h... 132 7e-29
gi|152974775|ref|YP_001374292.1| 4-hydroxyphenylacetate 3-m... 131 1e-28
gi|47498588|gb|AAT28189.1| 4-hydroxyphenylacetic acid 3-hyd... 131 1e-28
gi|138896797|ref|YP_001127250.1| Putative aromatic compound... 131 1e-28
gi|23100327|ref|NP_693794.1| 4-hydroxyphenylacetate-3-hydro... 128 1e-27
gi|72384120|ref|YP_293474.1| 4-hydroxyphenylacetate 3-hydro... 125 5e-27
gi|7672524|gb|AAF66546.1|AF140605_2 phenol 2-hydroxylase co... 124 2e-26
gi|15807887|ref|NP_285546.1| 4-hydroxyphenylacetate-3-hydro... 122 6e-26
gi|94971886|ref|YP_593926.1| 4-hydroxyphenylacetate 3-monoo... 120 2e-25
gi|24575103|gb|AAL06674.1| chlorophenol-4-monooxygenase [St... 117 1e-24
gi|118734039|ref|ZP_01582547.1| 4-hydroxyphenylacetate 3-hy... 116 4e-24
gi|116671115|ref|YP_832048.1| 4-hydroxyphenylacetate 3-mono... 115 6e-24
gi|148656690|ref|YP_001276895.1| 4-hydroxyphenylacetate 3-h... 114 1e-23
gi|78063257|ref|YP_373165.1| 4-hydroxyphenylacetate 3-hydro... 114 1e-23
gi|154244334|ref|YP_001415292.1| 4-hydroxyphenylacetate 3-h... 114 1e-23
gi|118713948|ref|ZP_01566510.1| 4-hydroxyphenylacetate 3-hy... 112 5e-23
gi|55978432|ref|YP_145488.1| phenol hydroxylase component A... 112 6e-23
gi|94496803|ref|ZP_01303378.1| 4-hydroxyphenylacetate 3-hyd... 112 6e-23
gi|156742383|ref|YP_001432512.1| 4-hydroxyphenylacetate 3-h... 112 7e-23
gi|15603388|ref|NP_246462.1| hypothetical protein PM1523 [P... 111 1e-22
gi|126727835|ref|ZP_01743664.1| 4-hydroxyphenylacetate-3-hy... 111 1e-22
gi|84353900|ref|ZP_00978820.1| COG2368: Aromatic ring hydro... 111 1e-22
gi|118046179|ref|ZP_01514832.1| 4-hydroxyphenylacetate 3-hy... 111 1e-22
gi|124875455|gb|EAY65445.1| 4-hydroxyphenylacetate 3-hydrox... 111 1e-22
gi|86741459|ref|YP_481859.1| 4-hydroxyphenylacetate 3-hydro... 110 2e-22
gi|118072117|ref|ZP_01540308.1| 4-hydroxyphenylacetate 3-hy... 108 7e-22
gi|116694447|ref|YP_728658.1| 4-Hydroxyphenylacetate-3-hydr... 108 8e-22
gi|110634806|ref|YP_675014.1| 4-hydroxyphenylacetate 3-hydr... 108 8e-22
gi|3046914|gb|AAC38324.1| phenol hydroxylase [Geobacillus t... 107 2e-21
gi|111020858|ref|YP_703830.1| aromatic ring hydroxylase [Rh... 107 2e-21
gi|37528090|ref|NP_931435.1| hypothetical protein plu4258 [... 107 2e-21
gi|152988198|ref|YP_001348345.1| pyoverdine biosynthesis pr... 106 3e-21
gi|116050203|ref|YP_790980.1| pyoverdine biosynthesis prote... 105 8e-21
gi|145595238|ref|YP_001159535.1| 4-hydroxyphenylacetate 3-h... 105 9e-21
gi|15597452|ref|NP_250946.1| pyoverdine biosynthesis protei... 104 1e-20
gi|2501842|gb|AAC21673.1| PvcC [Pseudomonas aeruginosa] 104 2e-20
gi|152973247|ref|YP_001338393.1| 4-hydroxyphenylacetate cat... 103 2e-20
gi|84327292|ref|ZP_00975313.1| COG2368: Aromatic ring hydro... 103 3e-20
gi|15920956|ref|NP_376625.1| hypothetical phenol hydroxylas... 103 3e-20
gi|75198162|ref|ZP_00708232.1| COG2368: Aromatic ring hydro... 103 3e-20
gi|74314781|ref|YP_313200.1| 4-hydroxyphenylacetate 3-monoo... 102 5e-20
gi|84321030|ref|ZP_00969395.1| COG2368: Aromatic ring hydro... 102 5e-20
gi|75258427|ref|ZP_00729858.1| COG2368: Aromatic ring hydro... 102 5e-20
gi|107101702|ref|ZP_01365620.1| hypothetical protein PaerPA... 102 5e-20
gi|38112622|gb|AAR11357.1| HpaB [Escherichia coli] 102 6e-20
gi|62179619|ref|YP_216036.1| 4-hydroxyphenylacetate catabol... 102 7e-20
gi|16764457|ref|NP_460072.1| 4-hydroxyphenylacetate catabol... 102 7e-20
gi|20454959|sp|Q57160|HPAB_ECOLI 4-hydroxyphenylacetate 3-m... 101 1e-19
gi|119881746|ref|ZP_01648039.1| 4-hydroxyphenylacetate 3-hy... 101 1e-19
gi|111019371|ref|YP_702343.1| phenol 2-monoxygenase, oxygen... 101 1e-19
gi|3002548|gb|AAC08739.1| 4-hydroxyphenylacetic acid hydrox... 101 1e-19
gi|86279133|gb|ABC88666.1| 4-coumarate 3-hydroxylase [Sacch... 101 1e-19
gi|20454956|sp|Q48440|HPAB_KLEOX 4-hydroxyphenylacetate 3-m... 101 1e-19
gi|75179307|ref|ZP_00699311.1| COG2368: Aromatic ring hydro... 100 2e-19
gi|76260468|ref|ZP_00768103.1| 4-hydroxyphenylacetate 3-hyd... 100 2e-19
gi|153948091|ref|YP_001401326.1| 4-hydroxyphenylacetate 3-m... 100 3e-19
gi|16122023|ref|NP_405336.1| 4-hydroxyphenylacetate 3-monoo... 100 3e-19
gi|82546699|ref|YP_410646.1| 4-hydroxyphenylacetate 3-monoo... 100 3e-19
gi|111019505|ref|YP_702477.1| phenol hydroxylase, oxygenase... 100 3e-19
gi|54024055|ref|YP_118297.1| putative 4-hydroxyphenylacetat... 99 5e-19
gi|126435227|ref|YP_001070918.1| 4-hydroxyphenylacetate 3-m... 99 5e-19
gi|56962664|ref|YP_174390.1| 4-hydroxyphenylacetate-3-hydro... 99 6e-19
gi|37524965|ref|NP_928309.1| 4-hydroxyphenylacetate 3-monoo... 99 6e-19
gi|27479670|gb|AAO17197.1| HpaB [Photorhabdus luminescens] 99 8e-19
gi|146304539|ref|YP_001191855.1| 4-hydroxyphenylacetate 3-h... 98 1e-18
gi|19570941|dbj|BAB86378.1| 4-nitrophenol hydroxylase compo... 98 2e-18
gi|118069797|ref|ZP_01538038.1| 4-hydroxyphenylacetate 3-mo... 96 4e-18
gi|154246515|ref|YP_001417473.1| 4-hydroxyphenylacetate 3-h... 96 4e-18
gi|70730720|ref|YP_260461.1| 4-hydroxyphenylacetate 3-monoo... 95 9e-18
gi|54026336|ref|YP_120578.1| putative phenol hydroxylase la... 95 1e-17
gi|70608003|ref|YP_256873.1| 4-hydroxyphenylacetate 3-monoo... 94 2e-17
gi|21954030|gb|AAC23548.2| chlorophenol-4-monooxygenase com... 94 2e-17
gi|37524265|ref|NP_927609.1| hypothetical protein plu0246 [... 94 3e-17
gi|111024862|ref|YP_707282.1| phenyl hydroxylase, oxygenase... 93 4e-17
gi|5833403|gb|AAD53503.1|AF144422_10 HpaB [Salmonella enter... 93 4e-17
gi|84325223|ref|ZP_00973263.1| COG2368: Aromatic ring hydro... 92 6e-17
gi|67511478|emb|CAJ01325.1| putative phenol hydroxylase lar... 92 1e-16
gi|53715965|ref|YP_106450.1| pyoverdin chromophore biosynth... 91 1e-16
gi|15898843|ref|NP_343448.1| 4-hydroxyphenylacetate-3-hydro... 91 2e-16
gi|116052127|ref|YP_789029.1| 4-hydroxyphenylacetate 3-mono... 91 2e-16
gi|15599286|ref|NP_252780.1| 4-hydroxyphenylacetate 3-monoo... 91 2e-16
gi|116670484|ref|YP_831417.1| 4-hydroxyphenylacetate 3-hydr... 91 2e-16
gi|152207437|gb|ABS30825.1| PheA1 [Rhodococcus erythropolis] 90 3e-16
gi|83717205|ref|YP_438433.1| pyoverdin chromophore biosynth... 90 3e-16
gi|152983981|ref|YP_001346393.1| 4-hydroxyphenylacetate 3-m... 90 4e-16
gi|847716|dbj|BAA13105.1| Chlorophenol-4-hydroxylase [Ralst... 89 9e-16
gi|126445435|ref|YP_001061326.1| chromophore biosynthetic p... 88 1e-15
gi|76817901|ref|YP_336838.1| pyoverdin chromophore biosynth... 88 1e-15
gi|100063566|ref|ZP_01325080.1| hypothetical protein BpseP_... 88 2e-15
gi|99911934|ref|ZP_01318736.1| hypothetical protein Bpse1_0... 87 2e-15
gi|53721198|ref|YP_110183.1| siderophore biosynthesis-relat... 87 2e-15
gi|108799584|ref|YP_639781.1| 4-hydroxyphenylacetate 3-mono... 86 8e-15
gi|15616398|ref|NP_244703.1| 4-hydroxyphenylacetate-3-hydro... 85 1e-14
gi|126731665|ref|ZP_01747470.1| putative phenol hydroxylase... 84 2e-14
gi|111020839|ref|YP_703811.1| aromatic ring hydroxylase [Rh... 84 2e-14
gi|37527879|ref|NP_931224.1| hypothetical protein plu4027 [... 83 4e-14
gi|146303772|ref|YP_001191088.1| 4-hydroxyphenylacetate 3-h... 82 1e-13
gi|54025025|ref|YP_119267.1| putative phenol hydroxylase la... 82 1e-13
gi|73541275|ref|YP_295795.1| 4-hydroxyphenylacetate 3-hydro... 81 2e-13
gi|16759979|ref|NP_455596.1| 4-hydroxyphenylacetate 3-monoo... 80 2e-13
gi|47568711|ref|ZP_00239407.1| 4-hydroxyphenylacetate-3-hyd... 80 3e-13
gi|126654193|ref|ZP_01725994.1| 4-hydroxyphenylacetate-3-hy... 80 3e-13
gi|119434078|gb|ABL75143.1| 4-nitrophenol monooxygenase [Ar... 80 3e-13
gi|42781661|ref|NP_978908.1| 4-hydroxyphenylacetate 3-hydro... 80 3e-13
gi|37547923|gb|AAN08754.1| putative chlorophenol monooxygen... 80 4e-13
gi|56420673|ref|YP_147991.1| 4-hydroxyphenylacetate-3-hydro... 79 8e-13
gi|68229094|ref|ZP_00568292.1| 4-hydroxyphenylacetate 3-hyd... 78 2e-12
gi|119961487|ref|YP_946424.1| putative 4-hydroxyphenylaceta... 77 3e-12
gi|118590246|ref|ZP_01547649.1| 4-hydroxyphenylacetate 3-mo... 76 4e-12
gi|24115573|ref|NP_710083.1| 4-hydroxyphenylacetate 3-monoo... 74 2e-11
gi|28377032|ref|NP_783924.1| 4-hydroxyphenylacetate-3-hydro... 71 2e-10
gi|154252236|ref|YP_001413060.1| 4-hydroxyphenylacetate 3-h... 70 2e-10
gi|16078922|ref|NP_389743.1| hypothetical protein BSU18620 ... 70 3e-10
gi|50428396|dbj|BAD30042.1| oxygenase component of 4-NP mon... 66 6e-09
gi|154684732|ref|YP_001419893.1| YoaI [Bacillus amyloliquef... 65 1e-08
gi|120404135|ref|YP_953964.1| 4-hydroxyphenylacetate 3-hydr... 64 2e-08
gi|89096535|ref|ZP_01169427.1| 4-hydroxyphenylacetate-3-hyd... 64 3e-08
gi|5295892|emb|CAB46018.1| hypothetical protein [Porphyromo... 62 9e-08
gi|10443727|gb|AAG17551.1|AF230879_1 putative phenazine hyd... 61 2e-07
>gi|34540488|ref|NP_904967.1| 4-hydroxybutyryl-CoA dehydratase [Porphyromonas gingivalis W83]
gi|34396801|gb|AAQ65866.1| 4-hydroxybutyryl-CoA dehydratase [Porphyromonas gingivalis W83]
Length = 486
Score = 983 bits (2540), Expect = 0.0, Method: Composition-based stats.
Identities = 486/486 (100%), Positives = 486/486 (100%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT
Sbjct: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ
Sbjct: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV
Sbjct: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME
Sbjct: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV
Sbjct: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI
Sbjct: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS
Sbjct: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI
Sbjct: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
Query: 481 DESLDK 486
DESLDK
Sbjct: 481 DESLDK 486
>gi|84028213|sp|P55792|HDVD_CLOAM Gamma-aminobutyrate metabolism dehydratase/isomerase [Includes:
4-hydroxybutyryl-CoA dehydratase ;
Vinylacetyl-CoA-Delta-isomerase ]
gi|70910046|emb|CAB60035.2| 4-Hydroxybutyryl-CoA dehydratase [Clostridium aminobutyricum]
Length = 490
Score = 776 bits (2004), Expect = 0.0, Method: Composition-based stats.
Identities = 369/488 (75%), Positives = 416/488 (85%), Gaps = 8/488 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT+EQY+ESLRKLN +VY GE+IEN VDHPMIRPS+N VAMTY+LA+ +Y LMT
Sbjct: 2 LMTAEQYIESLRKLNTRVYMFGEKIENWVDHPMIRPSINCVAMTYELAQDPQYADLMTTK 61
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SNL GK +NRF +LHQST+DL+ KVKMQRL+GQKTASCFQRCVGMDAFNA++STTYE+DQ
Sbjct: 62 SNLIGKTINRFANLHQSTDDLRKKVKMQRLLGQKTASCFQRCVGMDAFNAVFSTTYEIDQ 121
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YHK F EY+KY+Q+NDL+VDGAMTDPKGDRGL+PS Q DPDL+L IVE REDGIV
Sbjct: 122 KYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGDRGLAPSAQKDPDLFLRIVEKREDGIV 181
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG++NSHEH+IMPTIAM EAD DYAVSFA PSDA+G+ MIYGRQSCDTRKME
Sbjct: 182 VRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDADGLFMIYGRQSCDTRKME 241
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EGADIDLGN +FGG EALVVFD VF+PN+R+F+C+EY FAGMMVERFAGYHRQSYGGCKV
Sbjct: 242 EGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQSYGGCKV 301
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDV+IGAAALAADYNG KASH+KDKLIEM HLNETLY CGIACS+EG AGNY I
Sbjct: 302 GVGDVVIGAAALAADYNGAQKASHVKDKLIEMTHLNETLYCCGIACSAEGYPTAAGNYQI 361
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH--------PEIGPIVKKY 412
DLLLANVCKQNITR PYEI RLAEDIAGGLMVTMPS+ DF+ IG K+
Sbjct: 362 DLLLANVCKQNITRFPYEIVRLAEDIAGGLMVTMPSEADFKSETVVGRDGETIGDFCNKF 421
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
A A +TE RMRVLR +ENI LG +AVGYRTESMHGAGSPQAQRIMIARQG++ KK+
Sbjct: 422 FAAAPTCTTEERMRVLRFLENICLGASAVGYRTESMHGAGSPQAQRIMIARQGNINAKKE 481
Query: 473 LARAIAHI 480
LA+AIA I
Sbjct: 482 LAKAIAGI 489
>gi|58176904|pdb|1U8V|A Chain A, Crystal Structure Of 4-Hydroxybutyryl-Coa Dehydratase From
Clostridium Aminobutyricum: Radical Catalysis Involving
A [4fe-4s] Cluster And Flavin
gi|58176905|pdb|1U8V|B Chain B, Crystal Structure Of 4-Hydroxybutyryl-Coa Dehydratase From
Clostridium Aminobutyricum: Radical Catalysis Involving
A [4fe-4s] Cluster And Flavin
gi|58176906|pdb|1U8V|C Chain C, Crystal Structure Of 4-Hydroxybutyryl-Coa Dehydratase From
Clostridium Aminobutyricum: Radical Catalysis Involving
A [4fe-4s] Cluster And Flavin
gi|58176907|pdb|1U8V|D Chain D, Crystal Structure Of 4-Hydroxybutyryl-Coa Dehydratase From
Clostridium Aminobutyricum: Radical Catalysis Involving
A [4fe-4s] Cluster And Flavin
Length = 490
Score = 774 bits (1999), Expect = 0.0, Method: Composition-based stats.
Identities = 368/488 (75%), Positives = 415/488 (85%), Gaps = 8/488 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT+EQY+ESLRKLN +VY GE+IEN VDHPMIRPS+N V MTY+LA+ +Y LMT
Sbjct: 2 LMTAEQYIESLRKLNTRVYMFGEKIENWVDHPMIRPSINCVRMTYELAQDPQYADLMTTK 61
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SNL GK +NRF +LHQST+DL+ KVKMQRL+GQKTASCFQRCVGMDAFNA++STTYE+DQ
Sbjct: 62 SNLIGKTINRFANLHQSTDDLRKKVKMQRLLGQKTASCFQRCVGMDAFNAVFSTTYEIDQ 121
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YHK F EY+KY+Q+NDL+VDGAMTDPKGDRGL+PS Q DPDL+L IVE REDGIV
Sbjct: 122 KYGTNYHKNFTEYLKYIQENDLIVDGAMTDPKGDRGLAPSAQKDPDLFLRIVEKREDGIV 181
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG++NSHEH+IMPTIAM EAD DYAVSFA PSDA+G+ MIYGRQSCDTRKME
Sbjct: 182 VRGAKAHQTGSINSHEHIIMPTIAMTEADKDYAVSFACPSDADGLFMIYGRQSCDTRKME 241
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EGADIDLGN +FGG EALVVFD VF+PN+R+F+C+EY FAGMMVERFAGYHRQSYGGCKV
Sbjct: 242 EGADIDLGNKQFGGQEALVVFDNVFIPNDRIFLCQEYDFAGMMVERFAGYHRQSYGGCKV 301
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDV+IGAAALAADYNG KASH+KDKLIEM HLNETLY CGIACS+EG AGNY I
Sbjct: 302 GVGDVVIGAAALAADYNGAQKASHVKDKLIEMTHLNETLYCCGIACSAEGYPTAAGNYQI 361
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH--------PEIGPIVKKY 412
DLLLANVCKQNITR PYEI RLAEDIAGGLMVTMPS+ DF+ IG K+
Sbjct: 362 DLLLANVCKQNITRFPYEIVRLAEDIAGGLMVTMPSEADFKSETVVGRDGETIGDFCNKF 421
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
A A +TE RMRVLR +ENI LG +AVGYRTESMHGAGSPQAQRIMIARQG++ KK+
Sbjct: 422 FAAAPTCTTEERMRVLRFLENICLGASAVGYRTESMHGAGSPQAQRIMIARQGNINAKKE 481
Query: 473 LARAIAHI 480
LA+AIA I
Sbjct: 482 LAKAIAGI 489
>gi|126699959|ref|YP_001088856.1| gamma-aminobutyrate metabolism dehydratase/isomerase [Clostridium
difficile 630]
gi|145952752|ref|ZP_01801760.1| hypothetical protein CdifQ_04002710 [Clostridium difficile
QCD-32g58]
gi|115251396|emb|CAJ69228.1| gamma-aminobutyrate metabolism dehydratase/isomerase [includes:
4-hydroxybutyryl-coa dehydratase;
vinylacetyl-coa-delta-isomerase] [Clostridium difficile
630]
Length = 498
Score = 763 bits (1969), Expect = 0.0, Method: Composition-based stats.
Identities = 363/495 (73%), Positives = 418/495 (84%), Gaps = 10/495 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT QY+ESLRKLN KVY GE ++N VDHPMIRPS+N VA TY LA EY LMT T
Sbjct: 3 LMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVAATYDLAHDPEYADLMTVT 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SN+TG+++NRF HLHQS +DL KVKMQRL GQKTASCFQRCVGMDAFNA+YSTT+E D+
Sbjct: 63 SNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQRCVGMDAFNAVYSTTFECDK 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A GT YH F++Y+ Y+Q+NDLVVDGAMTDPKGDR LSPS Q DPD++LHIVE REDGI+
Sbjct: 123 AHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLSPSAQPDPDMFLHIVERREDGII 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG++NSHEHLIMPTI+M EAD DYAVSFAVPSDAEGV MIYGRQSCDTRK+E
Sbjct: 183 VRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSFAVPSDAEGVFMIYGRQSCDTRKLE 242
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EGAD+DLGN EFGG EALVVFD VFVPN+R+F+C E+ F+GM+VERFAGYHRQSYGGCKV
Sbjct: 243 EGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLCGEWDFSGMLVERFAGYHRQSYGGCKV 302
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDV+IGAAALAADYNG KASHIKDKLIEM HLNE+LY CGIACSSEG + +AGNY I
Sbjct: 303 GVGDVIIGAAALAADYNGANKASHIKDKLIEMTHLNESLYCCGIACSSEGHKTEAGNYQI 362
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHP--------EIGPIVKKY 412
DLLLANVCKQN+TR PYEI RLAEDIAGGLMVTMPS++DF+ IG + KY
Sbjct: 363 DLLLANVCKQNVTRFPYEIVRLAEDIAGGLMVTMPSEKDFKSDLKVGTSGMTIGEVCNKY 422
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
++ STE RMR+LR +ENI LG++AVGYRTESMHGAGSPQAQRIMI+RQG++ KK+
Sbjct: 423 FKASSVASTEERMRILRFLENICLGSSAVGYRTESMHGAGSPQAQRIMISRQGNINQKKE 482
Query: 473 LARAIAHI--DESLD 485
LA+ IA I +E+L+
Sbjct: 483 LAKKIAGIKKEEALN 497
>gi|121534266|ref|ZP_01666090.1| Vinylacetyl-CoA delta-isomerase [Thermosinus carboxydivorans Nor1]
gi|121307036|gb|EAX47954.1| Vinylacetyl-CoA delta-isomerase [Thermosinus carboxydivorans Nor1]
Length = 495
Score = 753 bits (1944), Expect = 0.0, Method: Composition-based stats.
Identities = 358/480 (74%), Positives = 413/480 (86%), Gaps = 1/480 (0%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T EQY ESLR+L LKVY GE +++PVDHP+IRPSMNSV MTY LA+ +Y+ LMTAT
Sbjct: 3 LKTPEQYEESLRQLKLKVYLQGELVKSPVDHPIIRPSMNSVKMTYALAQDPQYEDLMTAT 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+LTGK++NRFCHLHQS +DL KVKMQRL+GQKTA+CFQRCVGMDA NA+ S T+EMDQ
Sbjct: 63 SHLTGKKINRFCHLHQSVDDLIKKVKMQRLLGQKTAACFQRCVGMDAINAVDSVTFEMDQ 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
LGT YH+RF+++++ +QD D VDGAMTDPKGDR L P +QADPDLY+H+ E R DGIV
Sbjct: 123 KLGTKYHERFLKFLRRMQDEDWTVDGAMTDPKGDRSLPPHKQADPDLYVHVAEKRSDGIV 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
+ GAKAHQTGAVNSH L+MPT+ M + DADYAV FA P+DAEG+ IYGRQSCDTRK+E
Sbjct: 183 IRGAKAHQTGAVNSHWILVMPTMTMGKDDADYAVCFAAPADAEGIFYIYGRQSCDTRKLE 242
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
G DID+GN +FGGHEAL+VFD VF+P E VFMC EY+F+G +VERFAGYHRQSYGGCKV
Sbjct: 243 -GGDIDVGNKQFGGHEALMVFDNVFIPWENVFMCGEYEFSGALVERFAGYHRQSYGGCKV 301
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGAAALAA+YNG KASHIKDKLIEMIHLNETLYACGIACS+EG + +G Y+I
Sbjct: 302 GVGDVLIGAAALAAEYNGAAKASHIKDKLIEMIHLNETLYACGIACSAEGYKTASGTYLI 361
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
DLLLANVCKQN+TR PYEIARLAEDIAGGLMVTMPS+QD RHPEIG +V+KYL G
Sbjct: 362 DLLLANVCKQNVTRFPYEIARLAEDIAGGLMVTMPSEQDLRHPEIGKVVEKYLRGVASVP 421
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
TE RMRVLRLIEN+TLGTAAVGYRTESMHGAGSPQAQRIMI+RQ +LE KK+LA+AIA I
Sbjct: 422 TEYRMRVLRLIENLTLGTAAVGYRTESMHGAGSPQAQRIMISRQSNLEHKKELAKAIAGI 481
>gi|150016969|ref|YP_001309223.1| Vinylacetyl-CoA Delta-isomerase [Clostridium beijerinckii NCIMB
8052]
gi|149903434|gb|ABR34267.1| Vinylacetyl-CoA Delta-isomerase [Clostridium beijerinckii NCIMB
8052]
Length = 484
Score = 751 bits (1940), Expect = 0.0, Method: Composition-based stats.
Identities = 353/467 (75%), Positives = 410/467 (87%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T EQY+ESLRKLNLKVY G+ ++N VD+P+IRPS+NSVAMTY+LA+M EY+ LMTAT
Sbjct: 3 LKTKEQYIESLRKLNLKVYMFGKPVDNVVDNPIIRPSLNSVAMTYELAQMPEYEDLMTAT 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SNLTG++VNRF HLHQST+DL KVKMQRL+GQKTASCFQRCVGMDAFNA+YS+TYE+D+
Sbjct: 63 SNLTGEKVNRFAHLHQSTDDLIKKVKMQRLLGQKTASCFQRCVGMDAFNALYSSTYEIDK 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A GT YH+ F +++KYVQ+NDL VDGAMTDPKGDRGLSPS+QAD DLYL +VE REDG+V
Sbjct: 123 ACGTNYHENFNKFLKYVQENDLTVDGAMTDPKGDRGLSPSKQADGDLYLRVVERREDGVV 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAK HQTG +NSHE ++MPTIA+ D D+A+SFAVP+DAEG+I IYGRQSCDTRK+E
Sbjct: 183 VRGAKCHQTGMLNSHEVVVMPTIALTPNDKDWAISFAVPTDAEGIIHIYGRQSCDTRKLE 242
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
GADIDLGN+EFGG E L +FD VFVPNER+F+ E FAGM+VERFAGYHRQSYGGCKV
Sbjct: 243 PGADIDLGNAEFGGQETLTIFDNVFVPNERIFLNGETDFAGMIVERFAGYHRQSYGGCKV 302
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGAAA+AADYNG KASH+KDKLIEM HLNETL++CGIACS+ G++ +AGNY I
Sbjct: 303 GVGDVLIGAAAVAADYNGAHKASHVKDKLIEMTHLNETLFSCGIACSAMGSKTEAGNYYI 362
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
D LLANVCKQN+TR PYEI RLAEDIAGG+MVTMPS+ DF+ +IGP + KYL G S
Sbjct: 363 DNLLANVCKQNVTRFPYEICRLAEDIAGGIMVTMPSEADFKDEKIGPYIDKYLRGVNSVS 422
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDL 467
TENRMR+LRLIENI LGTAAVGYRTESMHGAGSPQAQRIMIARQG+L
Sbjct: 423 TENRMRILRLIENICLGTAAVGYRTESMHGAGSPQAQRIMIARQGNL 469
>gi|34763075|ref|ZP_00144047.1| 4-hydroxybutanoyl-CoA dehydratase; Vinylacetyl-CoA delta isomerase
[Fusobacterium nucleatum subsp. vincentii ATCC 49256]
gi|27887243|gb|EAA24342.1| 4-hydroxybutanoyl-CoA dehydratase; Vinylacetyl-CoA delta isomerase
[Fusobacterium nucleatum subsp. vincentii ATCC 49256]
Length = 486
Score = 739 bits (1909), Expect = 0.0, Method: Composition-based stats.
Identities = 349/481 (72%), Positives = 409/481 (85%), Gaps = 1/481 (0%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT +YVESLRKLN++VY GER+E PVDHP+IRPS+NSV MTY LA+ EY+ LMTAT
Sbjct: 6 LMTGNEYVESLRKLNMEVYIFGERVECPVDHPIIRPSLNSVKMTYDLAQEPEYEELMTAT 65
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+LTGK++NRF H+HQSTEDL KVKMQRL+GQKTASCFQRCVGMDAFNA YSTTY+MD+
Sbjct: 66 SHLTGKKINRFAHIHQSTEDLVKKVKMQRLLGQKTASCFQRCVGMDAFNACYSTTYDMDK 125
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
LGT YH++ +Y+ Y Q+NDL VDGAMTDPKGDRGL+PS QADPD++LHIVE REDGIV
Sbjct: 126 KLGTNYHEKLKKYIIYCQENDLTVDGAMTDPKGDRGLAPSAQADPDMFLHIVERREDGIV 185
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG VNSHE L+MPT++M EAD DY+V FAVP+D +G+ MIYGRQSCDTRK+
Sbjct: 186 VRGAKAHQTGMVNSHEVLVMPTLSMTEADKDYSVCFAVPTDTKGIKMIYGRQSCDTRKL- 244
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EG+ +D+GN +FGGHEALVVFD VFVPN+R+FMC EY+F+ +VERFAG+HRQSYGGCKV
Sbjct: 245 EGSKVDVGNPKFGGHEALVVFDNVFVPNDRIFMCGEYEFSNSLVERFAGFHRQSYGGCKV 304
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGA AL +DYNG KASHIKDK+IEM HLNETLY GIACSSEG + AG+Y I
Sbjct: 305 GVGDVLIGATALISDYNGTKKASHIKDKIIEMTHLNETLYCAGIACSSEGHKTAAGSYEI 364
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
DLLLANVCKQN+TR PYEIARLAEDIAGG++VT+PS+ D E+G V+KYL G
Sbjct: 365 DLLLANVCKQNVTRFPYEIARLAEDIAGGILVTLPSEADLNSKEVGHYVEKYLKGVATVP 424
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
T RM+VLR IEN+TLGTAAVGYRTES+HGAGSPQAQRIMI+RQ +LE KK+L + I I
Sbjct: 425 TLTRMKVLRFIENLTLGTAAVGYRTESLHGAGSPQAQRIMISRQSNLEAKKQLVKDILDI 484
Query: 481 D 481
D
Sbjct: 485 D 485
>gi|153955634|ref|YP_001396399.1| AbfD [Clostridium kluyveri DSM 555]
gi|146348492|gb|EDK35028.1| AbfD [Clostridium kluyveri DSM 555]
Length = 484
Score = 738 bits (1904), Expect = 0.0, Method: Composition-based stats.
Identities = 355/482 (73%), Positives = 418/482 (86%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT E+YVESLRKL L VY++GE+I+NPVD+P++RPS+NSV MTY LA+ EY+ LMT T
Sbjct: 3 LMTGEEYVESLRKLKLNVYYLGEKIDNPVDNPVLRPSLNSVKMTYDLAQEAEYEDLMTTT 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
SN+TG+++NRF +LHQS+EDL KVKMQRL GQKTA+CFQRCVGMD+FNA+YSTT+E+D+
Sbjct: 63 SNITGEKINRFTNLHQSSEDLVKKVKMQRLCGQKTAACFQRCVGMDSFNAVYSTTFEIDK 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
T Y + F +++ YVQ NDL VDGAMTDPKGDRGLSPS+QADPDLYL +VE REDG+V
Sbjct: 123 EYNTNYFENFKKFLTYVQKNDLTVDGAMTDPKGDRGLSPSKQADPDLYLRVVERREDGVV 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG NSHE L+MPTIAMR D DYA++F+VP+DAEG+ MI GRQSCDTRKME
Sbjct: 183 VRGAKAHQTGICNSHEVLVMPTIAMRPDDKDYAIAFSVPTDAEGITMIIGRQSCDTRKME 242
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
+ ADID+GN EFGG EALVVFD VFVPN+R+F+ E ++AGM+VERFAGYHRQSYGGCKV
Sbjct: 243 KDADIDVGNKEFGGVEALVVFDDVFVPNDRIFLNGETEYAGMLVERFAGYHRQSYGGCKV 302
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGAAA+AADYNG KASHIKDKLIEM+HLNETLYACGIACS+EG KAGNY I
Sbjct: 303 GVGDVLIGAAAVAADYNGAAKASHIKDKLIEMMHLNETLYACGIACSAEGHATKAGNYQI 362
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
DLLLANVCKQNITR PYEI RLAEDIAGGLMVTMPS++D++ PE+G V+KYL G
Sbjct: 363 DLLLANVCKQNITRFPYEIVRLAEDIAGGLMVTMPSEKDYKSPEVGKYVEKYLVGVASVP 422
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
E+RM++LRL+ENI LGTAAVGYRTESMHGAGSPQAQRIMI+RQG+L KKKLA+ IA I
Sbjct: 423 VEDRMKILRLLENICLGTAAVGYRTESMHGAGSPQAQRIMISRQGNLAHKKKLAKKIARI 482
Query: 481 DE 482
++
Sbjct: 483 ED 484
>gi|121540557|ref|ZP_01672318.1| Vinylacetyl-CoA delta-isomerase [Candidatus Desulfococcus
oleovorans Hxd3]
gi|121519642|gb|EAX56489.1| Vinylacetyl-CoA delta-isomerase [Candidatus Desulfococcus
oleovorans Hxd3]
Length = 484
Score = 653 bits (1684), Expect = 0.0, Method: Composition-based stats.
Identities = 312/467 (66%), Positives = 377/467 (80%), Gaps = 2/467 (0%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
MMT+E Y SLRKLNLKVY G+++ N VDHP+IRPSMN+VA TY+LA E++ +MTAT
Sbjct: 2 MMTAEAYEASLRKLNLKVYMFGQKVSNVVDHPIIRPSMNAVAKTYELAHRPEHEAIMTAT 61
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+LTGK++NRF H+HQST+DL K +M RL+G T CFQRCVGMD+ NA+ TT+++D
Sbjct: 62 SHLTGKKINRFTHIHQSTDDLVKKTRMGRLLGGATGCCFQRCVGMDSLNALSMTTFDIDA 121
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT Y+KRFI Y++YVQ+NDL DGAMTDPKGDR L P +Q DPDLYL +VEV+ DGIV
Sbjct: 122 KYGTEYNKRFIRYLEYVQENDLTCDGAMTDPKGDRSLPPHKQKDPDLYLRVVEVKPDGIV 181
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTGAVNSHE ++MPTI+MRE D DYAVSFA+PSDAEG+ I GRQSCDTRK+E
Sbjct: 182 VRGAKAHQTGAVNSHEVIVMPTISMREEDKDYAVSFALPSDAEGITYIMGRQSCDTRKLE 241
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
G ID GN FGGHEALVVFD VFVPN+R+FM KE++FAG +VERFA YHRQSY CKV
Sbjct: 242 MGT-IDRGNPFFGGHEALVVFDDVFVPNDRIFMLKEFEFAGHLVERFASYHRQSY-ACKV 299
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGA+ A+YNG KA HIKDK++EM HLNE+L+ +AC++ G + +G Y +
Sbjct: 300 GVGDVLIGASQTIAEYNGAEKAHHIKDKIVEMNHLNESLFCGSLACAATGHKEPSGTYYV 359
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
+ LLANV KQN+TR PYE++RLA+DIAGGLMVT+PS+QDF PE GP++KKY G
Sbjct: 360 NNLLANVFKQNVTRFPYELSRLAQDIAGGLMVTLPSEQDFNDPETGPVLKKYFQTRDGVL 419
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDL 467
ENR R+LRLIENITLGTAAVGY TESMHGAGSPQAQRIMI+R ++
Sbjct: 420 PENRARILRLIENITLGTAAVGYLTESMHGAGSPQAQRIMISRLANM 466
>gi|78043633|ref|YP_360148.1| gamma-aminobutyrate metabolism dehydratase/isomerase
[Carboxydothermus hydrogenoformans Z-2901]
gi|77995748|gb|ABB14647.1| gamma-aminobutyrate metabolism dehydratase/isomerase
[Carboxydothermus hydrogenoformans Z-2901]
Length = 491
Score = 649 bits (1674), Expect = 0.0, Method: Composition-based stats.
Identities = 307/483 (63%), Positives = 381/483 (78%), Gaps = 2/483 (0%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T ++Y+ SLR + +VYF GERIENPVDHP+IRPS+N+VAMTY LA +YK L TA
Sbjct: 3 LKTVKEYLNSLRAMKFEVYFRGERIENPVDHPVIRPSVNAVAMTYALAHNSKYKDLATAY 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S K VNRF H+HQST+DL KV++ R +GQ T CFQRCVGMD NA+Y+ TYE+D+
Sbjct: 63 SPFVDKYVNRFTHIHQSTDDLLKKVELLRTIGQLTGVCFQRCVGMDGLNAVYAVTYEIDE 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YH+RFI Y+KYVQ+NDLVVDGAMTDPKGDRGL PSEQ D DLYL +V+ E+GIV
Sbjct: 123 KYGTQYHQRFINYLKYVQENDLVVDGAMTDPKGDRGLRPSEQEDKDLYLRVVKETEEGIV 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMR-EADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
V GAK HQTGA+NSHE L+MPTI+++ E + YAVSFAVPSD+ G++ +YGRQ D R +
Sbjct: 183 VRGAKFHQTGAINSHEILVMPTISLKGEEEKPYAVSFAVPSDSPGIVYVYGRQPSDLRSL 242
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
+ + D GN +F G EA+V+F+ VFVP ERVFMC E +FAG +VE FA YHRQSYGGCK
Sbjct: 243 YDAPE-DCGNPKFAGQEAVVIFNDVFVPWERVFMCGEVEFAGNLVEYFASYHRQSYGGCK 301
Query: 300 VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYM 359
VGVGDVLIGAAA A++NGV KASHIKDK++EMIHLNET+++CG+ACS G + AGNYM
Sbjct: 302 VGVGDVLIGAAANIAEFNGVDKASHIKDKIVEMIHLNETIFSCGVACSCLGYKTSAGNYM 361
Query: 360 IDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGK 419
+D LLANVCKQN+TR+PYEIARL +DIAGGL VTMPS +D + ++G +++KYL G G
Sbjct: 362 VDRLLANVCKQNVTRMPYEIARLLQDIAGGLFVTMPSWKDLENGKVGELLQKYLVGKKGV 421
Query: 420 STENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAH 479
++R++++RLIEN+TLG +AVGY ESMHGAGSPQAQRIMI R D+E KKK A +A
Sbjct: 422 KVKDRVKLMRLIENLTLGRSAVGYLPESMHGAGSPQAQRIMITRLADIEKKKKFALRLAG 481
Query: 480 IDE 482
I E
Sbjct: 482 IGE 484
>gi|154241790|ref|ZP_02023352.1| Vinylacetyl-CoA Delta-isomerase [Candidatus Nitrosopumilus
maritimus SCM1]
gi|154203606|gb|EDN89577.1| Vinylacetyl-CoA Delta-isomerase [Candidatus Nitrosopumilus
maritimus SCM1]
Length = 508
Score = 607 bits (1566), Expect = e-172, Method: Composition-based stats.
Identities = 302/484 (62%), Positives = 380/484 (78%), Gaps = 4/484 (0%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
+ + Y+ESLR +LKVY GE ++ PVDHPMIRPS+N+VA TY LA +E L +A S+
Sbjct: 10 SGDDYIESLRGRDLKVYLFGELVKEPVDHPMIRPSINAVAETYDLALREE--ALASADSS 67
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
+TG +VNRF H+ +S EDL + KMQR +GQ T +CFQRCVGMDA N+++STT+E+D+
Sbjct: 68 ITGLKVNRFLHIAESAEDLVLQNKMQRKLGQNTGTCFQRCVGMDAMNSLHSTTFEIDEKH 127
Query: 123 GTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVS 182
GT YHKRF+E++K VQ +LV+ GAMTDPKGDR PSEQ DPDL+ IV+ E G+ VS
Sbjct: 128 GTDYHKRFLEFVKMVQQENLVIGGAMTDPKGDRSKGPSEQDDPDLFTRIVDTDEKGVYVS 187
Query: 183 GAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEG 242
GAKAHQTG +NSH ++MPTI + E+D D+A+ A+P+DA+GV IYGRQSCDTR MEEG
Sbjct: 188 GAKAHQTGCINSHWIILMPTIRLTESDKDWAIVGAIPADAKGVTYIYGRQSCDTRSMEEG 247
Query: 243 ADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVGV 302
DID GN++FGG EAL++ DRVF+P ++VFM EY+FA M+VERF YHR+SY CK G+
Sbjct: 248 -DIDDGNAKFGGQEALIILDRVFIPWDKVFMHGEYEFASMLVERFTCYHRRSYV-CKTGL 305
Query: 303 GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDL 362
GDVLIGAAA ADYNGVPK SHIKDK+IEM HLNET++A GIA S +G +MK+G Y+ D
Sbjct: 306 GDVLIGAAATIADYNGVPKVSHIKDKIIEMTHLNETIFAAGIASSHQGQKMKSGVYLNDD 365
Query: 363 LLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTE 422
+LA VCK N+TR PYEI+RLA+DIAGGL+VT+PS++DFRHPE GP++KKYLAG G E
Sbjct: 366 MLAQVCKHNVTRFPYEISRLAQDIAGGLVVTLPSEKDFRHPEAGPLLKKYLAGRKGVDVE 425
Query: 423 NRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHIDE 482
NRMR+LRLIEN+TLG AVGY TESMHGAGSPQAQRI I RQ + KK LA+ +A I
Sbjct: 426 NRMRILRLIENMTLGRNAVGYLTESMHGAGSPQAQRIQIQRQMQVGYKKNLAKNLAGITN 485
Query: 483 SLDK 486
+++
Sbjct: 486 DVEE 489
>gi|78223420|ref|YP_385167.1| 4-hydroxyphenylacetate 3-hydroxylase [Geobacter metallireducens
GS-15]
gi|78194675|gb|ABB32442.1| 4-hydroxyphenylacetate 3-hydroxylase [Geobacter metallireducens
GS-15]
Length = 483
Score = 588 bits (1515), Expect = e-166, Method: Composition-based stats.
Identities = 286/478 (59%), Positives = 363/478 (75%), Gaps = 7/478 (1%)
Query: 7 YVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTGK 66
Y ESLR LN+KVY GE+I++ VDHP+ +P +N+ A+T+ LA + L+TATS+LTG
Sbjct: 9 YRESLRALNIKVYAFGEKIDSIVDHPLFQPHINAAALTFDLAHDPTTEALVTATSHLTGS 68
Query: 67 QVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQALGTTY 126
+++RF H+HQST+DL KVKM RL+ KT SC+QRCVG DA NA Y+ TYEMDQ LGT Y
Sbjct: 69 KISRFTHIHQSTDDLIKKVKMLRLIAGKTGSCYQRCVGWDALNANYTVTYEMDQELGTDY 128
Query: 127 HKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAKA 186
H+RF Y++Y+QDNDL+V GAMTDPKGDRGL P++Q DPD+++H+V + GIV+ GAK
Sbjct: 129 HQRFRRYLEYIQDNDLMVAGAMTDPKGDRGLPPAKQKDPDMFVHVVAKNDKGIVIRGAKV 188
Query: 187 HQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADID 246
HQTG VNSHE LIMPT+AM E D DYAV+ A+P+D+ GVI I+GRQ+ DTR++E+G D+D
Sbjct: 189 HQTGIVNSHEMLIMPTMAMGEEDGDYAVACALPTDSPGVIHIFGRQTNDTRRLEKG-DLD 247
Query: 247 LGNSEFG--GHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVGVGD 304
GN+E+G G EAL + + VFVP ERVFMC EY++AG++VERFA YHRQ+YGGCK GV D
Sbjct: 248 QGNAEYGTVGGEALTILEDVFVPWERVFMCGEYKYAGLLVERFASYHRQNYGGCKAGVSD 307
Query: 305 VLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLL 364
V+IGA A+YNG KASH++DK++EM+HL ETLY IACS EG +G Y ++ LL
Sbjct: 308 VIIGATTAMAEYNGAAKASHVRDKIVEMVHLTETLYCGSIACSCEGAPTPSGAYFVNPLL 367
Query: 365 ANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENR 424
AN KQN+TR YEIARL+ DI+GG M TMPS++D H EIG V+KY G TE R
Sbjct: 368 ANTVKQNVTRFIYEIARLSHDISGGCMATMPSEKDLHHDEIGKYVEKYFRGVDEAPTEER 427
Query: 425 MRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHIDE 482
MR+ RL+EN+T GTA V ESMHGAGSPQAQR+MI RQ +L K KLA+ +A I E
Sbjct: 428 MRMARLVENMTGGTALV----ESMHGAGSPQAQRVMILRQANLGHKVKLAKKLAGIKE 481
>gi|118193755|gb|ABK76673.1| 4-hydroxybutyryl-CoA dehydratase [Cenarchaeum symbiosum A]
Length = 507
Score = 582 bits (1501), Expect = e-164, Method: Composition-based stats.
Identities = 293/476 (61%), Positives = 365/476 (76%), Gaps = 4/476 (0%)
Query: 5 EQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLT 64
+ Y++SLR +KVY MGE IEN VDHPMIRPS+N+VA TY LA + L + S LT
Sbjct: 8 DTYIDSLRGRKMKVYLMGELIENYVDHPMIRPSINAVAETYDLAVRE--PELASVESKLT 65
Query: 65 GKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQALGT 124
G+++NRF H+ +S +DL + KMQR +GQ T +CFQRCVGMDA NA++STTYE+D+ GT
Sbjct: 66 GRRINRFLHIVESPDDLVMQNKMQRKLGQNTGTCFQRCVGMDALNALHSTTYEIDEKHGT 125
Query: 125 TYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGA 184
TYHK+ ++++K +Q + V+ GAM+DPKGDR PSEQ DPDLY HIV + GI VSGA
Sbjct: 126 TYHKKLLDFIKMIQGENAVIGGAMSDPKGDRSKGPSEQVDPDLYTHIVAKDDKGIYVSGA 185
Query: 185 KAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGAD 244
KAHQTG +NSH +IMPT+ + E D D+AV A+P+DAEG+ IYGRQSCDTR MEEG D
Sbjct: 186 KAHQTGCINSHWIIIMPTMRLTEDDRDWAVVGAIPADAEGLTYIYGRQSCDTRSMEEG-D 244
Query: 245 IDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVGVGD 304
ID GN++F G EA+++ D+VFVP E +FM EY+FA M+VERF YHR+SY CK GVGD
Sbjct: 245 IDDGNAKFSGQEAMIILDKVFVPWEHIFMNGEYEFASMLVERFTCYHRRSYV-CKTGVGD 303
Query: 305 VLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLL 364
VLIGAA ADYNGVPK SHI++K+IEM HLNET+YA GIA S + +MK+G Y+ D +L
Sbjct: 304 VLIGAAGTIADYNGVPKVSHIREKMIEMTHLNETIYAAGIASSYQAQKMKSGVYLNDDML 363
Query: 365 ANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENR 424
A VCK N+T+ PYEIARL +DIAGGLMVT+PS++DFR+PE GP++KKYL G G ENR
Sbjct: 364 AQVCKHNVTKFPYEIARLTQDIAGGLMVTLPSEKDFRNPETGPLLKKYLVGRKGVDVENR 423
Query: 425 MRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
MR+LRLIEN+T+G AVGY TESMHGAGSPQAQRI I RQ L K LA+ +A I
Sbjct: 424 MRILRLIENMTMGRNAVGYLTESMHGAGSPQAQRIQIQRQMQLGYKMNLAKNLAGI 479
>gi|11497945|ref|NP_069169.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-1) [Archaeoglobus
fulgidus DSM 4304]
gi|2650300|gb|AAB90900.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-1) [Archaeoglobus
fulgidus DSM 4304]
Length = 500
Score = 582 bits (1500), Expect = e-164, Method: Composition-based stats.
Identities = 284/482 (58%), Positives = 369/482 (76%), Gaps = 8/482 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
MM ++Y+ESLRKL KVYFMG +I++ D P+ P +N+ AMTY+LA Y+ +MTAT
Sbjct: 4 MMNGKEYIESLRKLKPKVYFMGRKIDSVADDPITAPHVNAAAMTYELANDPRYEDVMTAT 63
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+LTG+++NRF H+HQSTEDL KV+M RL+G+KT SCFQRCVG+DA A+Y TTY++D+
Sbjct: 64 SHLTGEKINRFTHIHQSTEDLVKKVRMMRLLGRKTGSCFQRCVGLDALCALYITTYDVDR 123
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YH+RF +Y+ +VQ NDL+ GAMTD KGDR L P +QADPD+Y+ +VE REDGIV
Sbjct: 124 KYGTDYHERFKDYLIHVQKNDLMAAGAMTDVKGDRSLRPHQQADPDVYVRVVERREDGIV 183
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAH TGAVNSHE + +PT AM E D DYAV+FAVP DAEGV+MI+GRQ+ D R+++
Sbjct: 184 VRGAKAHITGAVNSHEIIALPTRAMGEEDKDYAVAFAVPVDAEGVVMIFGRQTNDVRRLD 243
Query: 241 EGADIDLGNSEFG--GHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
DID GN+++ G EAL++F+ VFVP ERVFMC EY FA +VE FA YHRQ+YGGC
Sbjct: 244 --GDIDCGNAKYATVGGEALIIFNDVFVPWERVFMCGEYDFASELVETFATYHRQNYGGC 301
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNY 358
KVGV DVLIGA+A A+YNGV +ASHI DKL EM+HL ET + C +ACS EG + +G Y
Sbjct: 302 KVGVADVLIGASAAIAEYNGVERASHIVDKLTEMVHLAETCWCCSLACSYEGFKTPSGAY 361
Query: 359 MIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATG 418
M +LLLANV K NITR PYE +RLA+DI GGL+ T PS+ D+++PE +++KYL G
Sbjct: 362 MPNLLLANVTKLNITRFPYEWSRLAQDIVGGLVATTPSELDYKNPETRDLIEKYLKGKAD 421
Query: 419 KSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
TE+R+R++RLIEN+++G ESMHGAGSP AQ+IMIAR+ +++ KK+ A+ +A
Sbjct: 422 VPTEHRVRMIRLIENLSIGAEL----PESMHGAGSPAAQKIMIARRANIDVKKEEAKRVA 477
Query: 479 HI 480
I
Sbjct: 478 GI 479
>gi|121535316|ref|ZP_01667129.1| Vinylacetyl-CoA delta-isomerase [Thermosinus carboxydivorans Nor1]
gi|121306102|gb|EAX47031.1| Vinylacetyl-CoA delta-isomerase [Thermosinus carboxydivorans Nor1]
Length = 495
Score = 577 bits (1487), Expect = e-163, Method: Composition-based stats.
Identities = 291/484 (60%), Positives = 363/484 (75%), Gaps = 10/484 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGE--RIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMT 58
M T ++Y++SLRK N+KVY G+ + E VDHP IR +NS A+TY LA Y+ LMT
Sbjct: 1 MKTGKEYIDSLRKRNIKVYVKGQLLKSEEVVDHPFIRGHVNSAALTYDLAHDPVYEDLMT 60
Query: 59 ATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEM 118
S+LTGK++NRF H+HQS +DL KVKM R++ QKT +C+QRCVG DA NA+Y+ TYEM
Sbjct: 61 VKSHLTGKKINRFTHIHQSVDDLVKKVKMLRMISQKTGTCYQRCVGFDALNALYTVTYEM 120
Query: 119 DQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
D+ LGT YH+RF +Y++YVQ+ND++V GAMTDPKGDR L PS+QADPDLY+H+VE + G
Sbjct: 121 DKKLGTEYHQRFKKYLEYVQENDIMVAGAMTDPKGDRSLRPSQQADPDLYVHVVEKNDKG 180
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IV+ GAKAH TG VNSHE LIMPT AM E D DYAVS AVP DA GV+ I+GRQ+ D RK
Sbjct: 181 IVIRGAKAHMTGMVNSHEMLIMPTTAMTEEDKDYAVSCAVPVDAPGVLHIFGRQTNDDRK 240
Query: 239 MEEGADIDLGNSEFG--GHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYG 296
E +ID GN+ +G G E L V + VFVP E+VFMC E +F+G++VERFA YHRQ+YG
Sbjct: 241 CE--GEIDQGNARYGIVGGECLTVLENVFVPWEKVFMCGETEFSGLLVERFACYHRQNYG 298
Query: 297 GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
GCK GV DV+IGAAA+ AD +G KA+HIK+K+ EMIHL ETLYAC IACS+EG +G
Sbjct: 299 GCKGGVSDVVIGAAAVMADMSGYGKAAHIKEKINEMIHLTETLYACSIACSAEGKPTASG 358
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGA 416
Y +D LLANV K N+TRL YEI RLA+DI GG+ TMPS+ D R+PEIG V+KYL G
Sbjct: 359 AYYVDPLLANVGKHNVTRLIYEIDRLAQDIGGGITATMPSESDLRNPEIGKYVEKYLKGV 418
Query: 417 TGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARA 476
+ TE RMR+ RLIEN+T GTA V ESMHGAGSPQAQ++ ++ +LE KK+ A
Sbjct: 419 STIPTEYRMRIARLIENMTGGTALV----ESMHGAGSPQAQKVFYSKLSNLEHKKRCALD 474
Query: 477 IAHI 480
IA +
Sbjct: 475 IAGV 478
>gi|149922906|ref|ZP_01911327.1| gamma-aminobutyrate metabolism dehydratase/isomerase [Plesiocystis
pacifica SIR-1]
gi|149816223|gb|EDM75729.1| gamma-aminobutyrate metabolism dehydratase/isomerase [Plesiocystis
pacifica SIR-1]
Length = 536
Score = 532 bits (1371), Expect = e-149, Method: Composition-based stats.
Identities = 269/482 (55%), Positives = 353/482 (73%), Gaps = 4/482 (0%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T Y+ SLR L+V++ G R+E PVDHP+IRPS+ +VA TY LA + L + T
Sbjct: 15 LRTGADYIASLRGRGLRVFYAGARVEEPVDHPVIRPSIQAVAETYDLAVRE--PELASVT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S +G++V+RF H+ +S EDL + KMQR +GQ T +CFQRCVGMDA NA++S T+++D
Sbjct: 73 SPSSGERVSRFLHVARSREDLVLQNKMQRRLGQLTGTCFQRCVGMDALNALHSVTHDIDA 132
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A T YH R +++ VQ +LV+ GAMTD KGDRG +P +QADPDL++H+VE R DG+V
Sbjct: 133 AHQTGYHARLEAFIELVQAGNLVIGGAMTDVKGDRGKAPHQQADPDLFVHVVERRADGVV 192
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
+ GAKAHQTG +NSH ++MPT+ + D DYA+ A+P DA G+ +YGRQSCD+R +E
Sbjct: 193 IRGAKAHQTGCINSHWLVVMPTMRLGPEDRDYAIIGAIPVDAPGITYVYGRQSCDSRSLE 252
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
A +D GN + G EALV+FD VF+P ERVFM E +FA +VERF YHR+SY CK
Sbjct: 253 PTA-LDRGNPRYAGQEALVIFDDVFIPTERVFMDGEVEFAATLVERFTCYHRRSYV-CKS 310
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
GVGDVLIGAAA A+ NGVP+ASHI+DKL+EM HLNET+YA GIA S +G +G Y+
Sbjct: 311 GVGDVLIGAAATIAEQNGVPRASHIRDKLVEMTHLNETIYATGIAASHQGQATASGAYIN 370
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
D +LANVCK ++TRLP+E+ RLA+D+AGGL+ T+P+ D E+GP+++KYLA S
Sbjct: 371 DEMLANVCKHHVTRLPFELGRLAQDLAGGLVATLPTGADLESEEVGPLLRKYLATTAEVS 430
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
E+R ++LRLIEN+TLG AVGY TES+HGAGSPQAQRI I RQ L+ KK+LAR IA I
Sbjct: 431 VEDRWKILRLIENMTLGRNAVGYLTESLHGAGSPQAQRIQIGRQQQLDYKKRLARRIAGI 490
Query: 481 DE 482
E
Sbjct: 491 GE 492
>gi|15899454|ref|NP_344059.1| 4-hydroxybutyryl-CoA dehydratase (abfD-2) [Sulfolobus solfataricus
P2]
gi|13816064|gb|AAK42849.1| 4-hydroxybutyryl-CoA dehydratase (abfD-2) [Sulfolobus solfataricus
P2]
Length = 502
Score = 450 bits (1158), Expect = e-125, Method: Composition-based stats.
Identities = 229/487 (47%), Positives = 331/487 (67%), Gaps = 9/487 (1%)
Query: 1 MMTSEQYVESLRKLN-LKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
+ T E+YV ++R N +++Y MG+ +++ +HP ++PS+ + TY A ++ + L A
Sbjct: 3 LRTGEEYVNAIRHRNKVEIYVMGKEVKDVTEHPFLKPSVLAFKATYDAAHEEDSESLARA 62
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
S+ ++VNRF H+H+S EDL KVK+ R + KT +CFQRCVG DA NAIY T+ M
Sbjct: 63 WSSFINEEVNRFTHIHRSPEDLAAKVKLLRKISHKTGACFQRCVGWDALNAIYVTSRLMA 122
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ Y++RF+EY+KYVQ ND+ + GAMTD KG R L P EQ P YL + +V +DGI
Sbjct: 123 ERGKKEYYERFVEYLKYVQKNDVALAGAMTDVKGIRTLRPHEQ--PHAYLRVTQVTKDGI 180
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAKA+ TG + E ++MPT AM E D D+AV+F++P D EG+ +I GRQ D R++
Sbjct: 181 YVSGAKANITGIGAAEEIVVMPTRAMSEKDMDFAVAFSIPLDTEGIKVIIGRQVNDGRRL 240
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
EEG +ID G HE LV+FD VFVP ERVFM ++Q +G++VE F+ YHRQ YGGCK
Sbjct: 241 EEG-EID-GLPYRTNHEGLVIFDNVFVPMERVFMLGDWQMSGILVEIFSSYHRQGYGGCK 298
Query: 300 VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM-KAGNY 358
G+GDV+IGAA A GV KA HI++KL EM+ LNE +Y GIA S + ++ + G +
Sbjct: 299 SGLGDVIIGAAYNLAKQIGVEKAPHIQNKLNEMVLLNENMYGSGIAASLDAVKLCEDGCW 358
Query: 359 MIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATG 418
++ + ANV KQ +TR PYEI + + DIAGG++ T PS+ D ++P++ P ++KYL G
Sbjct: 359 WVNPMFANVTKQLVTRFPYEITKFSTDIAGGIIGTAPSEWDLKNPKLKPYIEKYLQGMMD 418
Query: 419 KSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
STE+R+R++RL+EN+ +V + ES+HGAGSP+AQRI I R D E +K+A+ ++
Sbjct: 419 YSTEDRLRMVRLLENVGF---SVAFLIESVHGAGSPEAQRIAINRVYDYEYAEKIAKYLS 475
Query: 479 HIDESLD 485
I++ +D
Sbjct: 476 QIEKRID 482
>gi|116750562|ref|YP_847249.1| 4-hydroxyphenylacetate 3-hydroxylase [Syntrophobacter fumaroxidans
MPOB]
gi|116699626|gb|ABK18814.1| 4-hydroxyphenylacetate 3-hydroxylase [Syntrophobacter fumaroxidans
MPOB]
Length = 479
Score = 446 bits (1146), Expect = e-123, Method: Composition-based stats.
Identities = 222/481 (46%), Positives = 310/481 (64%), Gaps = 6/481 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T +Y+ESLR + VY GE+IE+ VD+P +R + + TY+LAE +EY+ L+
Sbjct: 3 LKTKAEYIESLRGMKPTVYMFGEKIESVVDNPRLRAGIEATGATYELAETEEYRPLIVTE 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S L + VNR+ S DL +VK+ RLMG + +CFQRC G+D +A+ TY++D
Sbjct: 63 SPLIHEPVNRYTLPPSSIADLVARVKINRLMGTRVGTCFQRCTGLDCLSALSIVTYDIDA 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
T Y KRFIE++K+VQ NDL + +TD KGDR L+P EQ D D+Y+ +VE DGIV
Sbjct: 123 KHSTPYFKRFIEFLKHVQKNDLTCNAGVTDVKGDRSLAPHEQEDKDMYVRVVERNADGIV 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAKAHQTG+++SHE +++PT A+R+ D DYA++FA+P+D G+I + GR S DTR+++
Sbjct: 183 VRGAKAHQTGSLSSHEIIVLPTRALRKGDEDYALAFAIPNDTPGLIHVVGRSSLDTRQLD 242
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
DLGN + + V+F VFVP ERVFMC E +FA MV RF+ YHRQS+GGCK
Sbjct: 243 ---GCDLGNLHYSKYCPTVIFKDVFVPWERVFMCGEVEFAVEMVNRFSAYHRQSHGGCKS 299
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
G D ++GAA DYNG KA H+K K IEM+H ETLY C +A S EG + +G Y I
Sbjct: 300 GKIDCMVGAALTMMDYNGTEKAGHLKQKAIEMVHRAETLYGCSLAASYEGKKEPSGTYFI 359
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
D +LAN K + + E RL DIAGG + +PS +D PE+G ++KKYL G
Sbjct: 360 DTVLANASKIHEGKEMSEAGRLLVDIAGGFVADLPSDRDLAIPEVGELLKKYLKGVASVP 419
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
E+R+++ RLIE + + +A +HG GSP+A RI I R+ +L+ KK A+ +A I
Sbjct: 420 VEDRVKMYRLIEKLVMESADT---ISDIHGGGSPEAHRITILRESNLKAKKDAAKRLAGI 476
Query: 481 D 481
+
Sbjct: 477 E 477
>gi|119871764|ref|YP_929771.1| Vinylacetyl-CoA delta-isomerase [Pyrobaculum islandicum DSM 4184]
gi|119673172|gb|ABL87428.1| Vinylacetyl-CoA delta-isomerase [Pyrobaculum islandicum DSM 4184]
Length = 498
Score = 439 bits (1128), Expect = e-121, Method: Composition-based stats.
Identities = 224/482 (46%), Positives = 321/482 (66%), Gaps = 8/482 (1%)
Query: 1 MMTSEQYVESLR-KLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
+ T EQYVE LR + ++KVY MG+R+E+ + ++PS+ S T+ A ++ + L A
Sbjct: 3 LRTGEQYVEGLRNRRHVKVYVMGKRVEDVTTNLFLKPSLLSFKATFDAAFQEDTRDLARA 62
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
S +++NRF H+HQ +DL KVK+ R + KT +CFQRCVG DA N +Y T +M
Sbjct: 63 YSPFINEEINRFVHIHQGPQDLVAKVKLLRALSHKTGTCFQRCVGWDALNTLYIITGKMA 122
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ Y +RF +Y++ VQ DL + GAMTD +G R L P EQ +PD Y+ +VE R+DGI
Sbjct: 123 EKGKPIYRERFFQYLEEVQRRDLALAGAMTDARGVRSLRPHEQPNPDAYVRVVEERDDGI 182
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
+V GAKA+ TG E ++MPT AM E DA YAV+FAVP D+ GV ++ GRQ D RK
Sbjct: 183 IVRGAKANITGVALVDEVIVMPTRAMTEKDAPYAVAFAVPLDSPGVTVVVGRQINDVRKA 242
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
E DID G HE L++F+ VFVP +RVF+ +E+Q+AG +VE F+ +HRQ Y GCK
Sbjct: 243 E--GDID-GLPYMSHHEGLIIFEDVFVPWDRVFLYQEWQWAGPLVEVFSAFHRQGYAGCK 299
Query: 300 VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ-MKAGNY 358
G+GDV+IGAA A GV +I DKL EM+ LNE++Y+ G+A S EG + +K G +
Sbjct: 300 SGLGDVIIGAAYNLAKQIGVADKPNIVDKLTEMVFLNESMYSAGLAASWEGKKLLKDGGW 359
Query: 359 MIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATG 418
++ + ANV K ++R PYEIARLA DIAGG++ T PS+ D ++ EI +V+KYL G
Sbjct: 360 WVNPMYANVTKHLVSRFPYEIARLAHDIAGGIIGTAPSEFDLKNSEIKHLVEKYLQGVPE 419
Query: 419 KSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
+ E+R+R+LRL+EN+++ +VG+ ES+HGAGSP AQ+I+ +R D +G + +AR +A
Sbjct: 420 FTAEDRLRMLRLLENVSI---SVGFLIESVHGAGSPAAQKIVFSRLYDFQGAETIARRLA 476
Query: 479 HI 480
+
Sbjct: 477 RM 478
>gi|146304087|ref|YP_001191403.1| Vinylacetyl-CoA Delta-isomerase [Metallosphaera sedula DSM 5348]
gi|145702337|gb|ABP95479.1| Vinylacetyl-CoA Delta-isomerase [Metallosphaera sedula DSM 5348]
Length = 507
Score = 438 bits (1126), Expect = e-121, Method: Composition-based stats.
Identities = 219/477 (45%), Positives = 319/477 (66%), Gaps = 6/477 (1%)
Query: 3 TSEQYVESL-RKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T EQY++S+ + +++Y MG +++ HP ++PS+ S T+ A ++ K L A S
Sbjct: 5 TGEQYLQSISNRSKVEIYVMGREVKDVTKHPFLKPSVMSFKATFDAAWEEDTKELGRAWS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+++NRF H+H+S +DL KVK+ R + KT +CFQRCVG D+ N ++ T M +
Sbjct: 65 PYLEEEINRFNHIHRSPDDLAAKVKLLRKLSHKTGACFQRCVGWDSLNTLHIVTTMMAKK 124
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
T RF+EY+KYVQ NDL + GAMTD KG R L PS+Q + + YL I EV +DGI V
Sbjct: 125 GKTEVRDRFVEYLKYVQKNDLALAGAMTDAKGIRNLKPSQQPNKNAYLRITEVTKDGIYV 184
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEE 241
SGAKA+ TG + E +++PT AM D DYAV+FA+P+D EGV ++ GRQ D R+MEE
Sbjct: 185 SGAKANITGVAATEEMVVLPTRAMGPEDKDYAVAFAIPTDTEGVKIVVGRQLNDARRMEE 244
Query: 242 GADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVG 301
G +ID G F HE LV+FD VFVP RVF+ E+++ G +VE F+ YHRQ YGGCK G
Sbjct: 245 G-EID-GLPYFYNHEGLVIFDNVFVPMNRVFLAGEWEYTGTLVEIFSAYHRQGYGGCKAG 302
Query: 302 VGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMID 361
+GDV+IGA+A A GV +ASH++DKL EMI L ET+Y+ GIA S +M + ++
Sbjct: 303 LGDVIIGASADLAKQIGVDRASHVQDKLTEMIFLTETMYSAGIAASLNAVKMCDNCWWVN 362
Query: 362 LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKST 421
+ ANV K + R P +IA+L+ D+AGG++ T PS+ D ++P++ + +YL GA +
Sbjct: 363 PMHANVTKHLVARFPSQIAQLSIDLAGGIVGTAPSEWDLKNPKLKEYISRYLQGAEDFTA 422
Query: 422 ENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
E+R+R++RL+EN+++G V ++ ES+HGAGSP AQRIM +R DL +++A+ +A
Sbjct: 423 EDRLRMVRLVENVSMG---VAFQIESVHGAGSPAAQRIMFSRLYDLNFAQEVAKKLA 476
>gi|18313522|ref|NP_560189.1| 4-hydroxyphenylacetate-3-hydroxylase, conjectural [Pyrobaculum
aerophilum str. IM2]
gi|18161062|gb|AAL64371.1| 4-hydroxyphenylacetate-3-hydroxylase, conjectural [Pyrobaculum
aerophilum str. IM2]
Length = 500
Score = 434 bits (1115), Expect = e-120, Method: Composition-based stats.
Identities = 235/487 (48%), Positives = 327/487 (67%), Gaps = 8/487 (1%)
Query: 1 MMTSEQYVESLRKL-NLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
+ T +QYVE LRK ++++Y MG+R+E+ HP ++PS+ S T+ A ++ + L A
Sbjct: 3 LRTGDQYVEGLRKRKHVEIYVMGKRVEDVTAHPFLKPSVKSFKATFDAAFDEDTRGLARA 62
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
S G+ VNRF H+HQ EDL KVK+ R + KT +CFQRCVG DA N +Y T ++
Sbjct: 63 YSPFIGEVVNRFVHIHQGPEDLVAKVKLLRKLSHKTGTCFQRCVGWDALNTLYIITGKIA 122
Query: 120 QALGT-TYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
+ G Y +RFIEY+KYVQ NDL + GAMTD KG R L PSEQ + D Y+ +VE REDG
Sbjct: 123 EREGRREYVERFIEYLKYVQKNDLALAGAMTDVKGVRTLRPSEQPNKDAYVRVVEEREDG 182
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IVV GAKA+ TG E ++MPT AM E DA+YA+SFA+P D GV ++ GRQ D+R+
Sbjct: 183 IVVRGAKANITGIAVVDEVIVMPTRAMTEKDAEYAISFAIPLDTPGVKVVVGRQLNDSRR 242
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
EEG +ID G HE ++F+ VFVP ERVF KE++++G+ VE F+ YHRQ Y GC
Sbjct: 243 FEEG-EID-GLPYMFNHEGFLIFEDVFVPWERVFFYKEWRWSGVFVEVFSNYHRQGYAGC 300
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ-MKAGN 357
K G+GDV+IGA+ A GV HI++KL EM LNET+Y+ G+A S E + ++ G
Sbjct: 301 KSGLGDVIIGASYGLARRLGVADKPHIQEKLTEMAFLNETMYSAGLAASWEARKLLRDGG 360
Query: 358 YMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGAT 417
+ ++ + ANV K +TR PYEI+RLA DIAGGL+ T PS+ DF++PE+ P+++KYL G
Sbjct: 361 WWVNPMYANVTKHLVTRFPYEISRLAHDIAGGLLGTAPSEADFKNPELRPLLEKYLQGVP 420
Query: 418 GKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAI 477
E R+R+LRL+EN ++ +V Y ES+HGAGSPQAQR+ I R D + +++A ++
Sbjct: 421 EFPAEERLRLLRLLENTSI---SVAYLIESVHGAGSPQAQRLSIQRVYDFQKVEQIASSL 477
Query: 478 AHIDESL 484
A I ++
Sbjct: 478 AGIKTAM 484
>gi|156937388|ref|YP_001435184.1| Vinylacetyl-CoA Delta-isomerase [Ignicoccus hospitalis KIN4/I]
gi|156566372|gb|ABU81777.1| Vinylacetyl-CoA Delta-isomerase [Ignicoccus hospitalis KIN4/I]
Length = 512
Score = 431 bits (1109), Expect = e-119, Method: Composition-based stats.
Identities = 230/498 (46%), Positives = 318/498 (63%), Gaps = 27/498 (5%)
Query: 5 EQYVESLRKLNLK--VYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEY-------KH 55
E+Y+ +LR+ + + +Y +GER+E+ HP P++ + TYK A D Y H
Sbjct: 7 EEYISALREKSKRAEIYVLGERVEDVTKHPFTLPAVKAFEWTYK-APWDPYFYDKEMGVH 65
Query: 56 LMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTT 115
L A S +++NRF H+HQS +DL KVK R + K SCFQRCVG DA N I +
Sbjct: 66 LAKAYSPFINEEINRFNHIHQSPQDLAIKVKYFRKLSHKAGSCFQRCVGWDAINTISIIS 125
Query: 116 YEMDQALGT------------TYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQA 163
Y++D+ TY++RF++++KYVQ D+ + G MTD KG R L P EQ
Sbjct: 126 YDIDKWYEQKGEKPEHFEHFGTYYERFLKFLKYVQKEDIALAGVMTDAKGVRSLRPHEQP 185
Query: 164 DPDLYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAE 223
+ D+Y+H+ EV ++GI+V GAKA+ TG V S E ++MPT AM E D D+A++FA P DAE
Sbjct: 186 NKDVYVHVKEVADEGIIVRGAKANITGVVASEEMIVMPTRAMTEKDKDFAIAFAAPIDAE 245
Query: 224 GVIMIYGRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMM 283
GV ++ GR + DTR+ EE ++D F EA+V+FD VFVP ERVFM +EYQFA +
Sbjct: 246 GVTLVVGRYTNDTRRFEE-PNVDALPGVFPA-EAIVIFDDVFVPWERVFMFREYQFAAEL 303
Query: 284 VERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACG 343
VE F+ YHRQ+YGGCK G+ DV+IG A A G+ HI++KL EMI L E ++A G
Sbjct: 304 VEIFSSYHRQAYGGCKPGLADVIIGGAYHLAKQMGIANKCHIREKLTEMIFLTEAMHAGG 363
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHP 403
+A + EG + +G Y +D + ANV KQ +TR PYEIARLA DIAGGL+ T+PS +D H
Sbjct: 364 LAAAWEGKKAASGTYYVDQMKANVTKQMVTRFPYEIARLAHDIAGGLIGTLPSYKDLMHE 423
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIAR 463
+IG +++YL E R RVLRL+ENITL +V + ES+HGAGSP+AQRI + R
Sbjct: 424 KIGKYLQQYLQCLPDYPAEWRHRVLRLLENITL---SVEFLIESVHGAGSPEAQRIWMRR 480
Query: 464 QGDLEGKKKLARAIAHID 481
LE + +A ++A I+
Sbjct: 481 FYPLEEMEDVALSLAGIN 498
>gi|70607859|ref|YP_256729.1| gamma-aminobutyrate metabolism dehydratase/isomerase [Sulfolobus
acidocaldarius DSM 639]
gi|68568507|gb|AAY81436.1| gamma-aminobutyrate metabolism dehydratase/isomerase [Sulfolobus
acidocaldarius DSM 639]
Length = 505
Score = 431 bits (1108), Expect = e-119, Method: Composition-based stats.
Identities = 218/477 (45%), Positives = 317/477 (66%), Gaps = 6/477 (1%)
Query: 3 TSEQYVESLRKLN-LKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T +QYV S+ K + +++Y +G+ +++ HP ++PS+ S T+ A ++ K L A S
Sbjct: 5 TGDQYVSSISKRSKVEIYVLGKEVKDVTKHPFLKPSVMSFKATFDAAWDEDTKELGRAWS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+++NRF H+H+S EDL KVK+ R + KT +CFQRCVG D+ N + T M
Sbjct: 65 PYLEEEINRFNHIHRSPEDLAAKVKLLRKLSHKTGACFQRCVGWDSLNTLNIVTKIMANK 124
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
T RF+EY+KYVQ NDL + GAMTD KG R L PS+Q + + YL + EV +DGI V
Sbjct: 125 GRTEPRDRFVEYLKYVQKNDLALAGAMTDVKGIRTLKPSQQPNKNAYLRVTEVTKDGIYV 184
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEE 241
SGAKA+ TG + E +++PT AM D DYAV+FA+P+D EG+ ++ GRQ D R+MEE
Sbjct: 185 SGAKANITGVAATEEMVVLPTRAMGPEDKDYAVAFAIPTDTEGIKIVVGRQINDARRMEE 244
Query: 242 GADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVG 301
G +ID G F HE LV+FD VFVP RVF+ E+++ G +VE FA YHRQ YGGCK G
Sbjct: 245 G-EID-GLPYFYNHEGLVIFDNVFVPMNRVFLAGEWEYTGTLVEIFAAYHRQGYGGCKAG 302
Query: 302 VGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMID 361
+GDV+IGA+A A GV KA H++DKL EMI L ET+Y+ GIA S ++ + ++
Sbjct: 303 LGDVIIGASADLARQIGVEKAPHVQDKLTEMIFLTETMYSAGIAASLNAVKICDNCWWVN 362
Query: 362 LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKST 421
+ ANV K + R P +I++LA DIAGG++ T PS+ D ++P++ + +YL G +
Sbjct: 363 PMHANVTKHLVARFPAQISQLAIDIAGGMVGTAPSEWDLKNPKLKEYIMRYLQGVEDFTA 422
Query: 422 ENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
E+R+R++RLIEN+++G V ++ ES+HGAGSP AQRIM +R DL+ +++++ +A
Sbjct: 423 EDRLRMVRLIENVSMG---VAFQIESIHGAGSPAAQRIMFSRLYDLDLAREISKKLA 476
>gi|15921962|ref|NP_377631.1| hypothetical 4-hydroxyphenylacetate 3-monooxygenase large subunit
[Sulfolobus tokodaii str. 7]
gi|15622750|dbj|BAB66740.1| 502aa long hypothetical 4-hydroxyphenylacetate 3-monooxygenase
large subunit [Sulfolobus tokodaii str. 7]
Length = 502
Score = 431 bits (1107), Expect = e-119, Method: Composition-based stats.
Identities = 217/477 (45%), Positives = 314/477 (65%), Gaps = 6/477 (1%)
Query: 3 TSEQYVESLRKLN-LKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T EQY++S++ N ++Y MG+ +++ HP ++PS+ + T+ A ++ K L A S
Sbjct: 5 TGEQYLDSIKIRNKAEIYVMGKEVKDVTTHPFLKPSVMAFKATFDAAWEEDTKELARAWS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
++VNRF H+H+S EDL KVK+ R + KT +CFQRCVG DA N ++ T M Q
Sbjct: 65 PFINEEVNRFNHIHRSPEDLAAKVKLLRKLSHKTGACFQRCVGWDALNTLWIMTNIMAQK 124
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
Y RF+EY+ YVQ DL + GAMTD KG R L P +Q + + Y+ I EV +DGI V
Sbjct: 125 GKKEYKDRFVEYLSYVQKKDLALAGAMTDAKGVRTLKPHQQPNKNAYVRIEEVTKDGIYV 184
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEE 241
SGAKA+ TG + E +++PT AM D DYAV+F++P+D EG+ +I GRQ D R++ E
Sbjct: 185 SGAKANITGVAATEEIVVLPTRAMGPEDKDYAVAFSIPTDTEGIKIIVGRQLNDARRL-E 243
Query: 242 GADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVG 301
G DID F HE LV+FD VFVP +RVF+ EY+F +VE F+ YHRQ YGGCK G
Sbjct: 244 GGDID-ALPYFYNHEGLVIFDHVFVPMDRVFLMGEYEFTSQLVEVFSAYHRQGYGGCKAG 302
Query: 302 VGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMID 361
+GDV+IGA+ A GV KASH+++KL EMI L ET+Y+ GIA S ++ + ++
Sbjct: 303 LGDVIIGASMNLAKQLGVEKASHVQEKLTEMIFLTETMYSAGIAASLNAVKVCDNCWWVN 362
Query: 362 LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKST 421
+ ANV K + R P +I++L+ DIAGG++ T PS+ D ++P++ + KYL G G +
Sbjct: 363 PMHANVTKHLVARFPAQISQLSIDIAGGIIGTAPSEWDLKNPKLREYIAKYLQGVEGYTA 422
Query: 422 ENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIA 478
E+R+R++RL+EN++LG V ++ ES+HGAGSP AQRIM +R DL +++A+ +A
Sbjct: 423 EDRLRMVRLLENVSLG---VAFQIESVHGAGSPAAQRIMFSRLYDLNYAEEVAKRLA 476
>gi|78044808|ref|YP_360550.1| 4-hydroxyphenylacetate 3-hydroxylase family protein
[Carboxydothermus hydrogenoformans Z-2901]
gi|77996923|gb|ABB15822.1| 4-hydroxyphenylacetate 3-hydroxylase family protein
[Carboxydothermus hydrogenoformans Z-2901]
Length = 475
Score = 429 bits (1103), Expect = e-118, Method: Composition-based stats.
Identities = 223/482 (46%), Positives = 308/482 (63%), Gaps = 7/482 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T+E+Y+E L K+ VY+ GE I D P +RP +N + T+ A +Y+ L+TAT
Sbjct: 1 MRTAEEYMEKLFKMRKNVYYNGELIGR--DDPRLRPGINVICETFNYAANPQYEELLTAT 58
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+LTGK++NRF H+HQS EDL K +M R M Q+ C QRC+G+DA NA+ T +MD
Sbjct: 59 SHLTGKKINRFTHIHQSPEDLLKKQEMTRFMCQRVGGCVQRCMGIDALNALSVVTKDMDD 118
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
ALGT YH+RF+ Y+KY Q+NDLV + A TD KGDR L P +QADPDLYL +VE R+DGIV
Sbjct: 119 ALGTNYHERFLNYLKYYQENDLVGNCAQTDVKGDRSLRPHQQADPDLYLRVVEKRKDGIV 178
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAKAH T A + E +++PT M E D D+AV+FAVP+DAEG+ I + R+
Sbjct: 179 VSGAKAHNTIAPYADEIIVLPTRMMTEKDKDWAVAFAVPADAEGITQIIRISNPRPRQ-- 236
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
+D + +G ++L VFDRVFVP ERVFMC E+Q+AG + FA YHR SY GCK
Sbjct: 237 ---KLDAPYANYGSADSLTVFDRVFVPWERVFMCGEWQYAGQLALLFATYHRHSYTGCKP 293
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
V D+++G AAL A+YNGV KASH++D L E+I + E +Y GIA + + +G Y+
Sbjct: 294 AVTDIIMGTAALVAEYNGVEKASHVRDALAELIAVAELVYGAGIAAGVKAKRAASGTYIP 353
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
+++ ANV + + Y L ++AGGL T+P + DF + E ++KYL G S
Sbjct: 354 EVVYANVARYHAGVNVYREFELLAELAGGLPATLPPEGDFYNEETKGYLEKYLMRKAGIS 413
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
EN+ R R I ++ + A + +HG GSP ++I I Q ++E KKKLA+ +A I
Sbjct: 414 AENQHRCFRFISDLLVSAQAGVKQVAGVHGGGSPIMEKITIYGQYNIEEKKKLAKYLAGI 473
Query: 481 DE 482
E
Sbjct: 474 KE 475
>gi|126460004|ref|YP_001056282.1| Vinylacetyl-CoA Delta-isomerase [Pyrobaculum calidifontis JCM
11548]
gi|126249725|gb|ABO08816.1| Vinylacetyl-CoA Delta-isomerase [Pyrobaculum calidifontis JCM
11548]
Length = 503
Score = 429 bits (1102), Expect = e-118, Method: Composition-based stats.
Identities = 221/486 (45%), Positives = 322/486 (66%), Gaps = 9/486 (1%)
Query: 1 MMTSEQYVESLRKLN-LKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
+ T +QYVE ++ N K+Y +G+R+ + + ++PS+ S T+ A ++ + L
Sbjct: 5 LRTGDQYVEGIKTRNKAKIYVLGKRVHDVTTNLFLKPSVLSFKATFDAAFEEDTRDLARV 64
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
S G++VNRF +H +DL KVK+ R + KT +CFQRCVG DA N +Y T ++
Sbjct: 65 YSPFAGEEVNRFNSIHMGPQDLVAKVKLLRKLSHKTGTCFQRCVGWDALNTLYIVTKKLA 124
Query: 120 QALGT-TYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
+ G Y+K FI+Y++YVQ DL + GAMTD KG R L PSEQ +PD Y+ +VE R+DG
Sbjct: 125 EKEGKGIYYKNFIKYLEYVQRRDLALAGAMTDVKGVRPLKPSEQPNPDAYVRVVEERDDG 184
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IVV GAKA+ TG E ++MPT AM E D YA+SFA+P D EGV ++ GRQ D R+
Sbjct: 185 IVVRGAKANITGIAVVDEVVVMPTRAMTEKDEVYAISFAIPLDTEGVTVVVGRQLNDARR 244
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
+EEG +ID G HE L++ + V+VP +RVFM +E+++AG++VE F+ YHRQ Y GC
Sbjct: 245 LEEG-EID-GLPYMFNHEGLLILEDVYVPWDRVFMYREWKWAGVLVEVFSAYHRQGYAGC 302
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN- 357
K G+GDV+IGAA A GV H+++KL EM+ LNET+Y+ G+A S EG ++ G+
Sbjct: 303 KSGLGDVIIGAAYNLAKQIGVADKPHVREKLTEMVFLNETMYSAGLAASWEGKKLVEGDG 362
Query: 358 -YMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGA 416
+ ++ + ANV K +TR PYE++RLA DIAGGL+ T PS+ D ++ E+G +V KYL G
Sbjct: 363 GWWVNPMYANVTKHLVTRFPYEVSRLAHDIAGGLLGTAPSEFDLKNEEVGKLVAKYLQGV 422
Query: 417 TGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARA 476
+ E+R+R+LRL+EN ++ +V Y ES+HGAGSPQAQRI + R D +K+A++
Sbjct: 423 PEFTAEDRLRMLRLLENTSI---SVAYLVESVHGAGSPQAQRISMERIYDFYTVEKIAKS 479
Query: 477 IAHIDE 482
+A + +
Sbjct: 480 LARMGQ 485
>gi|85858564|ref|YP_460766.1| aromatic ring hydroxylase [Syntrophus aciditrophicus SB]
gi|85721655|gb|ABC76598.1| aromatic ring hydroxylase [Syntrophus aciditrophicus SB]
Length = 479
Score = 421 bits (1083), Expect = e-116, Method: Composition-based stats.
Identities = 216/481 (44%), Positives = 302/481 (62%), Gaps = 7/481 (1%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPV-DHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T E+Y+ES+R L VY GE++ V D+P +R + + TY+LA M E + L TS
Sbjct: 5 TKEEYIESIRALKPTVYMFGEKLTTSVVDNPRLRAGIEATGATYELANMPENRDLFITTS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
L + VNRF S EDL +VK+ R + +C QRC G+D + + TY++D+
Sbjct: 65 PLINEPVNRFTLPPASIEDLVARVKINRKVANYVGTCHQRCTGLDCLSTLAIVTYDIDKK 124
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
GT Y+ FIE++KY+Q NDL + +TD KGDR L+P Q D D++L +VE REDGIVV
Sbjct: 125 YGTHYNDNFIEFLKYMQKNDLTGNAGVTDVKGDRSLAPHAQVDKDMFLRVVEKREDGIVV 184
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEE 241
GAK+HQTG+++SHE +++PT AM + D DY+V+FA+PSD G+I + GR S D R++E
Sbjct: 185 RGAKSHQTGSLSSHEIIVLPTRAMGKDDGDYSVAFAIPSDTPGLIHVVGRSSLDMREIE- 243
Query: 242 GADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVG 301
D GN + + ++F+ VFVP RVFMC E +FA MV +F+ +HRQS+GGCK G
Sbjct: 244 --GCDCGNVYYSKYCPTLIFNDVFVPWNRVFMCGETEFAVDMVVKFSSFHRQSHGGCKSG 301
Query: 302 VGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMID 361
D + GAA DYNG K SH+K K+I+MIH ETLY C +A S EG Q +GNY ID
Sbjct: 302 KIDCMTGAALTMMDYNGTAKMSHLKQKVIDMIHRAETLYGCCLASSYEGKQQPSGNYFID 361
Query: 362 LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKST 421
+LAN K + + E RL D AGG + +PS +DF +PEIG ++KKYL G
Sbjct: 362 TVLANASKIHEGKEMAEATRLMIDCAGGYVADLPSDRDFSNPEIGDLLKKYLKGVDKIPV 421
Query: 422 ENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHID 481
E+R+++ RLIE + + +A +HG GS +A R+ I R+ D E KKK A+ +A I
Sbjct: 422 EDRVKMFRLIEKMAMESADT---ISDIHGGGSAEAHRVTIFRESDTESKKKAAKRLAGIK 478
Query: 482 E 482
+
Sbjct: 479 D 479
>gi|147677557|ref|YP_001211772.1| aromatic ring hydroxylase [Pelotomaculum thermopropionicum SI]
gi|146273654|dbj|BAF59403.1| aromatic ring hydroxylase [Pelotomaculum thermopropionicum SI]
Length = 480
Score = 379 bits (974), Expect = e-103, Method: Composition-based stats.
Identities = 206/487 (42%), Positives = 304/487 (62%), Gaps = 13/487 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T+ +Y+ES++ N ++ F+G R N ++P + + A Y+L++ +Y +MTA
Sbjct: 1 MKTAAEYLESMKAYNPRI-FLGGRQVNLHENPTTLTVLRANARVYELSQEPDYADIMTAV 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S TG++V+R HL ST DL+ + +M L Q +C RCVG D NA+ T+EM++
Sbjct: 60 SPYTGQKVSRNLHLAASTADLEKRAEMATLTSQMLGTCNYRCVGADVINALAGVTWEMNR 119
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
LGT YH RF++++KY+Q+NDL V GA+TD KGDR P++Q D D+Y+H+VE + DGIV
Sbjct: 120 ELGTEYHTRFLKHLKYLQENDLAVSGAVTDAKGDRSKRPAQQEDRDVYVHVVEKKPDGIV 179
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAK Q+GA +HE +++PT+ +RE + ++A++FAVP+ AEG+ I + + T + E
Sbjct: 180 VRGAKVSQSGAFAAHETIVIPTMGLREGEENFALAFAVPNGAEGLTYIC-QYTPFTAERE 238
Query: 241 EGADID-LGNSEFGGHEALV-VFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGG- 297
D+ LGN +G E V VFD VF+P E VFMC E Q+AG ++ RFA HR + GG
Sbjct: 239 LAPDVKYLGNPLYGQRETCVMVFDNVFIPWEHVFMCGEVQYAGRLIARFAKTHRMNCGGA 298
Query: 298 CKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
CKVG D++IGAA LAA+Y+GV KA HI DK+ EMI ++ET AC IA + +G + AG+
Sbjct: 299 CKVGFADLIIGAAQLAAEYSGVQKAPHIIDKITEMIRISETARACTIAAALKGREEPAGS 358
Query: 358 --YMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
+ D + N K I +EI + DI GG+ VTMPS+ + +P V+K++
Sbjct: 359 GFFQPDDIFGNAAKLTIADGFWEIMKWVGDIGGGMAVTMPSELELENPATSGYVRKFMKA 418
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLAR 475
+ E R+RV + I+N G G + HGAGSP AQ++ + DLE KK LAR
Sbjct: 419 SA--PAEKRLRVAKFIQNWCAGLHGAG----TWHGAGSPMAQKMALYALADLEKKKALAR 472
Query: 476 AIAHIDE 482
+A + +
Sbjct: 473 NLAGLKD 479
>gi|147678105|ref|YP_001212320.1| aromatic ring hydroxylase [Pelotomaculum thermopropionicum SI]
gi|146274202|dbj|BAF59951.1| aromatic ring hydroxylase [Pelotomaculum thermopropionicum SI]
Length = 488
Score = 348 bits (893), Expect = 5e-94, Method: Composition-based stats.
Identities = 190/487 (39%), Positives = 285/487 (58%), Gaps = 12/487 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T E Y++SL+ + VY GE I++ HP R ++ S A + ++ EY + T
Sbjct: 3 LKTREDYLKSLKAMRPNVYKFGELIKDVTTHPATRRTVESHARAFDMSHDSEYADIFTTV 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQ-RCVGMDAFNAIYSTTYEMD 119
S+ TG++++R+ + + E++ K++R M + T +C CVG +A N +++ TYEMD
Sbjct: 63 SSFTGEKIHRWTSMMTNLEEIMYNAKLKRAMYRVTGTCAGGLCVGWNALNVMWNVTYEMD 122
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ GT Y +R +++ Q+ LVV GA+TD KGDR L PS+Q+DPD L I EVREDGI
Sbjct: 123 KEYGTNYQERLKKWILQAQEKGLVVAGALTDAKGDRSLRPSQQSDPDSNLRIKEVREDGI 182
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
V+SG K G S+E ++P RE D DYA++ VP D EG+ ++ R+ D+R+
Sbjct: 183 VISGFKTMICGVAASNEIFLLPGSGYREDDQDYALACVVPRDIEGLTIVETRRPSDSREY 242
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
EEG DI E G +A ++F FVPNERVFMCKEY++ G +++ F +R G C
Sbjct: 243 EEGFDI----PETGITQAYLLFTDCFVPNERVFMCKEYKYTGKIIQYFTANYRACIGACV 298
Query: 300 VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYM 359
G GDV+IGAAAL A NG+ ++ I +K+I+M NET Y GI + G Q AG ++
Sbjct: 299 AGQGDVMIGAAALMARTNGLAASTFI-NKIIDMAINNETTYGVGIGAMALGKQHPAGCWV 357
Query: 360 IDLLLANVCKQNITRLPYEIARLAEDIAGGLMVT--MPSQQDFRHPEIGPIVKKYLAGAT 417
D L+A+ K ++ LPYE RL +DI GG++ T PS +DF P G +V++ + +
Sbjct: 358 SDSLMAHTNKVHVATLPYETKRLCQDIGGGIVETGCFPSYKDFNDPLYGHLVQRAVKASD 417
Query: 418 GKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAI 477
S E R R RL+E +TLG G MHG GSP ++++ ++ + AR +
Sbjct: 418 KFSAETRARAARLVEWLTLGAGVPG----CMHGGGSPDGAKLVVRANTPIDLYAEYARKV 473
Query: 478 AHIDESL 484
A I E +
Sbjct: 474 AGITEEV 480
>gi|11498632|ref|NP_069860.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-3) [Archaeoglobus
fulgidus DSM 4304]
gi|2649567|gb|AAB90216.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-3) [Archaeoglobus
fulgidus DSM 4304]
Length = 480
Score = 348 bits (892), Expect = 7e-94, Method: Composition-based stats.
Identities = 186/486 (38%), Positives = 280/486 (57%), Gaps = 7/486 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M TSE+Y + L KL VY G+++ D P + +N ++ T+ L E +YK L+T
Sbjct: 1 MRTSEEYRQDLYKLKPNVYVRGKKVRR--DSPEVSGGINVISKTFDLVEHPDYKDLLTTK 58
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S+++GK++NRF H++QS EDL K M R + + C QRC+G DA N + T+ D
Sbjct: 59 SHISGKRINRFTHINQSAEDLLKKQLMTRKLCRLVGGCIQRCMGCDAINGLSVATFAADT 118
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YHKRF+EY+K Q+ DLV A TD KGDR P +Q DPD+Y+ +VE R DGIV
Sbjct: 119 EHGTDYHKRFLEYVKEFQERDLVAACAQTDVKGDRSKRPHQQDDPDMYVRVVERRSDGIV 178
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAK T A + E +++PT AM D DY+V+FAVP+D EGV ++ T K+
Sbjct: 179 VRGAKNCITMAAVADEIIVVPTRAMTPEDKDYSVAFAVPADTEGVKIV-----ARTSKLR 233
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
+ + E G E +++FD VFVP +RVF+C E ++A + FA +HR SY GCK
Sbjct: 234 APEGLKMPQGEIGDDENMIIFDDVFVPWDRVFLCGENKYATLAAHLFALFHRHSYTGCKP 293
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
D+++G AL A+YNGV + +I++KL+E+ E ++A G+A + G + AG ++
Sbjct: 294 ATTDMIMGFGALIAEYNGVYEKHNIREKLVELAATAELVFAAGVAAAHYGQKSPAGTFIP 353
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKS 420
+ + ANV +++ Y+ + +++GGL +P +DF E+GP ++KY+
Sbjct: 354 NEVYANVGRRHAGLNYYKELEILAELSGGLPAALPFAEDFLSEEVGPYIRKYIKRRADVP 413
Query: 421 TENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
E+ R L I NI + +HG GSP + I I R D E KK +A+ ++ I
Sbjct: 414 AEHVYRCLFGISNILCSSLGGVQAVAGVHGGGSPVMEEIAIWRSYDFEKKKDIAKYLSGI 473
Query: 481 DESLDK 486
E L +
Sbjct: 474 SEELPR 479
>gi|116751349|ref|YP_848036.1| 4-hydroxyphenylacetate 3-hydroxylase [Syntrophobacter fumaroxidans
MPOB]
gi|116700413|gb|ABK19601.1| 4-hydroxyphenylacetate 3-hydroxylase [Syntrophobacter fumaroxidans
MPOB]
Length = 487
Score = 329 bits (843), Expect = 3e-88, Method: Composition-based stats.
Identities = 188/487 (38%), Positives = 274/487 (56%), Gaps = 12/487 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T Y++SL+ + +Y GE IE+ H R ++ S A + + +Y +
Sbjct: 3 LKTRADYLKSLKGMRPNIYKFGELIEDVTAHAATRRTVESHARGFDASHDPKYAQDFSTV 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQ-RCVGMDAFNAIYSTTYEMD 119
S+ TG++++R+ + ++ ED+ K++R M + T SC CVG +A N +++ T +D
Sbjct: 63 SSFTGEKIHRWNSMMETLEDIMGNSKLKRWMYRFTGSCNGGLCVGWNAQNVMWNVTALID 122
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ GT Y +R +++ Q+ LVV GA+TD KGDR L PS+QADPD +H+ EVR+DGI
Sbjct: 123 KECGTHYQERLKKWILGAQEKGLVVAGALTDAKGDRSLRPSQQADPDSNVHVKEVRKDGI 182
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
V+SG KA G S+E I+P R+ D DYAV VP D EG+ ++ R+ DTR+M
Sbjct: 183 VISGTKAMICGVAASNEIFILPGSGYRDEDKDYAVVVVVPRDIEGLTIVETRRPSDTREM 242
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
E+G DI E G +A + F FVPNERVFMC+E +FAG ++E F +R G C
Sbjct: 243 EDGFDI----PEMGITQAFLFFQDCFVPNERVFMCQEAKFAGKVIEYFTANYRACIGACV 298
Query: 300 VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYM 359
G GDV+IGA AL A NG+ A+ K++EM NET Y GI + G + G ++
Sbjct: 299 AGQGDVMIGAGALMARTNGLAAAT-FSAKMVEMAVNNETTYCMGIGAMALGKKGPGGMWV 357
Query: 360 IDLLLANVCKQNITRLPYEIARLAEDIAGGLMVT--MPSQQDFRHPEIGPIVKKYLAGAT 417
D L A+ K ++ LPYE RL +DI GG++ T PS +DF P+ G +V+K L +
Sbjct: 358 ADSLTAHTNKVHVATLPYETKRLCQDIGGGVVETGCFPSSKDFNDPKYGHLVRKALQASA 417
Query: 418 GKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAI 477
S E R R RL E +TLG G MHG GSP ++++ + AR I
Sbjct: 418 KFSAETRARAARLSEWLTLGAGVPG----CMHGGGSPDGAKLVVRAFTPVNEFADYARKI 473
Query: 478 AHIDESL 484
A I E +
Sbjct: 474 AGITEEV 480
>gi|119505692|ref|ZP_01627762.1| 4-hydroxyphenylacetate 3-hydroxylase family protein [marine gamma
proteobacterium HTCC2080]
gi|119458504|gb|EAW39609.1| 4-hydroxyphenylacetate 3-hydroxylase family protein [marine gamma
proteobacterium HTCC2080]
Length = 524
Score = 319 bits (817), Expect = 3e-85, Method: Composition-based stats.
Identities = 180/479 (37%), Positives = 274/479 (57%), Gaps = 16/479 (3%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+M++E+Y ESLR + VY G+ IE+ D P + P + +V +TY A+ E+ +M A
Sbjct: 9 IMSAEEYRESLRSYSPTVYVDGDLIESVADEPRLAPGIRAVGVTYDFAQKPEFGGVMLAD 68
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEM-D 119
+GK VNR H+++ +EDL K++ RL+ +++ C QR + DA NAIY +T+ M D
Sbjct: 69 QASSGKTVNRMLHINRHSEDLLSKLEAVRLLCRESG-CAQRYLTHDALNAIYQSTWRMAD 127
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ G+ YH RF++Y+ +QD DL + AMTD KG+R L P Q++PD Y+HI E R DGI
Sbjct: 128 ETSGSEYHSRFLDYLHDIQDRDLTLGVAMTDAKGERRLRPHAQSNPDAYVHISERRADGI 187
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMI---YGRQSCDT 236
V+SG KA TG HE L+MP M D D+AV AVP DA+G+ ++ GR
Sbjct: 188 VLSGTKAIVTGGPYMHELLVMPCRTMVAGDTDFAVCCAVPIDAKGLTVVARPAGRPGQAA 247
Query: 237 RKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYG 296
K ++++G A+ F VFVP +RVFM E+ +V +A +HR S
Sbjct: 248 AKF---------SAQYGQSTAVCHFSEVFVPWDRVFMAGEWDQTEHLVTSYANHHRHSCI 298
Query: 297 GCKVGVGDVLIGAAALAADYNGV--PKASHIKDKLIEMIHLNETLYACGIACSSEGTQMK 354
G + G GD+LIGA AL D NG+ SH+++ ++E+I + E YACG+A S G Q
Sbjct: 299 GARAGFGDLLIGAGALMTDANGLDMDDVSHLRETMVELIKIVEGFYACGVAASVYGIQDP 358
Query: 355 AGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLA 414
G++M + + +N+ K + Y++ R A +++GGL+V +P + +P + L+
Sbjct: 359 CGSWMPEPVFSNIGKLLLATQIYDMHRTAHEVSGGLIVALPGPDEDHNPATAGDLAAVLS 418
Query: 415 GATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKL 473
+ RM V R IE++T + Y S+HG GSPQA + I R+ +E +K L
Sbjct: 419 ARPDVPYDKRMEVSRFIEDLTASSTGGWYSVISLHGGGSPQAMKREIYRRYPVEERKAL 477
>gi|145588557|ref|YP_001155154.1| Vinylacetyl-CoA Delta-isomerase [Polynucleobacter sp. QLW-P1DMWA-1]
gi|145046963|gb|ABP33590.1| Vinylacetyl-CoA Delta-isomerase [Polynucleobacter sp. QLW-P1DMWA-1]
Length = 529
Score = 300 bits (767), Expect = 2e-79, Method: Composition-based stats.
Identities = 176/476 (36%), Positives = 267/476 (56%), Gaps = 9/476 (1%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
M S+ Y ESLR L VY G IE+ D P +RP + ++ +TY + LM A S
Sbjct: 9 MNSKDYQESLRSLKPTVYVDGRLIESVADEPSLRPGVQALGVTYDMVHDPALAPLMLADS 68
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
N G V R H++QS+ DL +K++ R++ Q+T C QR + DA NAI + +D A
Sbjct: 69 N--GTPVPRMLHINQSSGDLLNKLEAVRVLCQETG-CAQRYLAHDALNAIAQVSARIDDA 125
Query: 122 LGTTYHK-RFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
G+ H +F EY+ +VQ DL + AMTD KGDR P EQ +PD Y+HIV G+V
Sbjct: 126 KGSNEHSAKFSEYLSHVQTKDLALGIAMTDAKGDRSRRPHEQENPDTYVHIVSQDAKGVV 185
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
+SG KA TGA HE L+MP M + DA +A+ AVP DA+G+ ++ K+E
Sbjct: 186 ISGTKAIVTGAPYMHEFLVMPGRNMTKEDAAFAICCAVPVDAKGITIVARPAGRPGDKVE 245
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
G I +S++G +V+FD+VFVP +RVF E++ + ++ +A +HR S +
Sbjct: 246 HGKPI--FSSKYGQSTGVVIFDKVFVPWDRVFYAGEWEHSSVLTYNYATHHRHSCIAARA 303
Query: 301 GVGDVLIGAAALAADYNGVPKA--SHIKDKLIEMIHLNETLYACGIACSSEGTQMK-AGN 357
G GD+LIGA AL + NG+ A S+++D ++E+I + E YACG+A S GTQ + +
Sbjct: 304 GFGDLLIGAGALMCEANGLDPATKSNLRDPMVELIKITEGFYACGVAASVYGTQDPYSKS 363
Query: 358 YMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGAT 417
+M + + +N+ K + Y++ RLA +++GGL+V +P + +P + + L
Sbjct: 364 FMPEPVFSNIGKLLLATQIYDMHRLAHEVSGGLIVALPGPDEDHNPATAATLAEVLRANP 423
Query: 418 GKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKL 473
+ R+ V R IE++T Y S+HG GSP A + I RQ + K +L
Sbjct: 424 AVPYDKRIEVARFIEDLTASYQGGWYSVISLHGGGSPAAMKQEIYRQYPIGNKVEL 479
>gi|124267702|ref|YP_001021706.1| Vinylacetyl-CoA delta-isomerase [Methylibium petroleiphilum PM1]
gi|124260477|gb|ABM95471.1| Vinylacetyl-CoA delta-isomerase [Methylibium petroleiphilum PM1]
Length = 542
Score = 297 bits (761), Expect = 1e-78, Method: Composition-based stats.
Identities = 177/480 (36%), Positives = 269/480 (56%), Gaps = 10/480 (2%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+M+ Y +SLR+ VY G+R+++ D P +RP +N++A TY A L A
Sbjct: 16 LMSGADYRDSLRRYKPTVYVDGQRVDSVADAPSLRPGVNALAYTYDFARDPAMAPLALAV 75
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+ G VNR H+++S DL +K++ RL+ Q+T C QR + DA N I + +D
Sbjct: 76 QSSRGFTVNRMAHVNESAGDLLNKLEAVRLLCQETG-CAQRYLMHDALNGIAQVSARLDD 134
Query: 121 ALGTTYHK-RFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
A G+T H+ RF Y+ VQD DL + AMTD KGDR P +QA+PD Y+H+VE GI
Sbjct: 135 AKGSTEHRARFQAYLARVQDEDLSLGVAMTDAKGDRSKRPHQQANPDTYVHVVERNGKGI 194
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
V+SG KA TGA HE L+MP M DAD+AV AVP DA G+ ++ K+
Sbjct: 195 VISGTKAIVTGAPYMHELLVMPGRNMGAEDADFAVCCAVPIDAPGMTLVSRPAGRPGDKL 254
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMC---KEYQFAGMMVERFAGYHRQSYG 296
E GA L + +G A+V+FDRVFVP ERVF E++ +G++ +A +HR S
Sbjct: 255 EHGA--ALFSRRYGQATAVVIFDRVFVPWERVFYAGQDGEWEHSGVLTYSYATHHRHSCI 312
Query: 297 GCKVGVGDVLIGAAALAADYNGVP--KASHIKDKLIEMIHLNETLYACGIACSSEGT-QM 353
+ G GD+LIGA AL + NG + S++++ ++E+I + E +ACG+A S GT
Sbjct: 313 AARAGFGDLLIGAGALMCEANGFDPGEKSNLREPMVELIKITEGFFACGVAASVYGTADP 372
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
+G++M + + +N+ K ++ Y++ RLA +++GGL+V +P + +P + + L
Sbjct: 373 YSGSFMPEPVFSNIGKLLMSTQIYDMHRLAHEVSGGLIVALPGPDEDHNPATAATLSEVL 432
Query: 414 AGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKL 473
+ R+ V R IE++T Y S+HG GSP A + I R + K +L
Sbjct: 433 RANPTVPYDKRIEVARFIEDLTASYQGGWYSVISLHGGGSPAALKQEIWRNYPVGSKVEL 492
>gi|149376166|ref|ZP_01893931.1| 4-hydroxyphenylacetate 3-hydroxylase family protein [Marinobacter
algicola DG893]
gi|149359571|gb|EDM48030.1| 4-hydroxyphenylacetate 3-hydroxylase family protein [Marinobacter
algicola DG893]
Length = 548
Score = 288 bits (737), Expect = 6e-76, Method: Composition-based stats.
Identities = 167/477 (35%), Positives = 268/477 (56%), Gaps = 7/477 (1%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+M+ + Y ESLRK N KV+ G ++ + VD P RP +N++A TY A E + + AT
Sbjct: 30 LMSGDDYRESLRKYNPKVFVDGRQVASVVDEPAFRPGINALAFTYDYALQPELEPIALAT 89
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+ + V+R H+++S+ DL +K++ R++ Q+T C QR + DA N + +D
Sbjct: 90 QSNRNRVVSRMLHVNESSGDLLNKLEAVRVLCQETG-CAQRYLAHDALNGVAQAVARIDD 148
Query: 121 ALGTTYHK-RFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
A GTT H+ RF Y+ + QD DL + AMTD KGDR P +QA+PD Y+HIVE GI
Sbjct: 149 AKGTTKHRDRFNAYLAHAQDEDLSIGVAMTDAKGDRSKKPHQQANPDTYVHIVEKNGKGI 208
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
V+SG KA TG HE L+MP M D +AV AV D G+ ++ K+
Sbjct: 209 VISGTKAIVTGGPYMHELLVMPGRDMGVEDKIFAVCCAVRVDDPGITIVSRPAGRPGEKL 268
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
E G L + ++G A+V+FDRVFVP +RVF +++ + ++ +A +HR S +
Sbjct: 269 EHGD--ALFSRKYGQSTAVVMFDRVFVPWDRVFYAGDWEHSNVLTYSYATHHRHSCIAAR 326
Query: 300 VGVGDVLIGAAALAADYNGVPKA--SHIKDKLIEMIHLNETLYACGIACSSEGTQMK-AG 356
G GD+LIGA AL + NG+ S+++++++E+I + E +ACG++ S TQ + +G
Sbjct: 327 AGFGDLLIGAGALMCEANGLNPGSKSNLREQMVELIKITEGFFACGVSASVYATQDQYSG 386
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGA 416
++M D + +N+ K + Y++ R+A +++GGL+V +P + +P + + L
Sbjct: 387 SFMPDPVYSNIGKLLLATQIYDMHRIAHEVSGGLIVALPGPDEDHNPATAAKLSEVLQAN 446
Query: 417 TGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKL 473
+ R++ R IE++T Y S+HG GSP A + I R + K +L
Sbjct: 447 PDIPYDKRIQTARFIEDLTASYQGGWYSVISLHGGGSPAAMKQEIWRNYPVGSKVEL 503
>gi|89897478|ref|YP_520965.1| hypothetical protein DSY4732 [Desulfitobacterium hafniense Y51]
gi|89336926|dbj|BAE86521.1| hypothetical protein [Desulfitobacterium hafniense Y51]
Length = 524
Score = 280 bits (715), Expect = 2e-73, Method: Composition-based stats.
Identities = 167/494 (33%), Positives = 257/494 (52%), Gaps = 25/494 (5%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T E Y E L K+ VY G++++ I + Y LA EY + TATS+
Sbjct: 5 TYEAYRERLLKMKPNVYLNGQKVDR--SGSWIDGGCYVMKQNYDLANDPEYADVCTATSH 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
LTG+++NRF H+HQS EDL +K M RL+ C QRC+G DA NA+ TY+ D+A
Sbjct: 63 LTGEKINRFTHIHQSREDLLNKQMMTRLLCHHVGGCTQRCMGSDALNALAVVTYDCDEAC 122
Query: 123 GTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSE---QADPDLYLHIVEVRED-- 177
GT Y +RF +Y+ Y Q+NDL+ + A TD KG R Q DPD ++H+++ D
Sbjct: 123 GTKYQERFNKYLLYCQENDLICNCAQTDVKGSRNPKYKRAHMQPDPDQFVHVIKTDVDGI 182
Query: 178 --------GIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIY 229
GI+V GAK + A E ++ PT M + D YA++FA+P+D +G+ ++
Sbjct: 183 GVDGKPCKGIIVRGAKICNSNAPYVDEIIVNPTKFMGKGDEGYALAFALPADWDGIKLMA 242
Query: 230 GRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMC-----KEYQFAGMMV 284
RK E ++ G E+L +FD VFVP +RVFM Q+AG +
Sbjct: 243 LPGQHHKRKHLEAP-----FNKVGDVESLTIFDDVFVPEDRVFMNGFDHPDVVQYAGYLA 297
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
FA +HR SY GCK V +V+ AAL AD N + K H+++K+ E+I E ++A G
Sbjct: 298 LMFAHFHRHSYTGCKTAVSEVIGAQAALVADVNDIAKEHHVREKVCEIISTAELVFAAGQ 357
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPE 404
A + + G+++ D +L N ++ + Y D+ GG+ ++P+++ F PE
Sbjct: 358 ASALRAVKFPNGSWVPDEILTNAGRKLAGQKIYHEYETLADLTGGICASLPTEESFFAPE 417
Query: 405 IGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQ 464
+ KY+ + E RV+R++E+ +HG GSP + I + +
Sbjct: 418 TAELCNKYIMRNPDYTAEETHRVMRMMEDKLCDAFESAQAVAGVHGGGSPLMETITMMSR 477
Query: 465 GDLEGKKKLARAIA 478
DLE K +A+ +A
Sbjct: 478 YDLEPLKDIAKYLA 491
>gi|11498490|ref|NP_069718.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-2) [Archaeoglobus
fulgidus DSM 4304]
gi|2649720|gb|AAB90358.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA-2) [Archaeoglobus
fulgidus DSM 4304]
Length = 461
Score = 269 bits (687), Expect = 3e-70, Method: Composition-based stats.
Identities = 164/476 (34%), Positives = 255/476 (53%), Gaps = 22/476 (4%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
++ E+Y+E L + +Y +G++IE+ V+HP IRP++ ++A TY +AE
Sbjct: 2 LLKPEEYIERLGEYKRDIYVLGKKIEDFVNHPNIRPTVEAMAYTYSIAEK------YAPH 55
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S L G++VNR +++Q+ EDL + QR + K A+C RC G DA NAIY T +D+
Sbjct: 56 SELVGEKVNRLNYVNQTFEDLIARYDYQRELSLKLATCNYRCTGCDAINAIYPATKALDE 115
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
GT YH+RF+E +K +Q D A+TD KGDRG PSEQ D YL +VE REDGIV
Sbjct: 116 REGTDYHRRFLELLKEIQKKDYACTAALTDVKGDRGKRPSEQKDK--YLRVVEKREDGIV 173
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GAK Q+GA + + ++PT R + ++AV FA + EG+ I K
Sbjct: 174 VRGAKICQSGAFAADVNFVLPTQTFRPGEEEFAVVFAAMPEDEGIKYILQNTGIQA-KQR 232
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKV 300
EG + GN +VVFD VF+P ERVF+ ++ + A +V FA HR CK
Sbjct: 233 EGGKFEAGNKYGDRTTCMVVFDDVFIPWERVFVFEDLKAARDVVSYFAPSHRCVGAACKA 292
Query: 301 GVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
G D + GAA+L +G+ S ++ K+ EM+ ++E +A + + +G G ++
Sbjct: 293 GFIDSMAGAASLMLKTSGLENVSALQQKVAEMVAVSEGAFAISVGAAVKGANHN-GCWLP 351
Query: 361 DLLLANVCKQ-NITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGK 419
+ +AN K + + L DI+GG++ T PS+ D +V +L +
Sbjct: 352 NFQMANSGKVIGVEGFAKALMNLI-DISGGIIGTSPSEFDLE------MVGDFLRASEKF 404
Query: 420 STENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLAR 475
+ E R+++++ IE T + VG + HG GSP A I + DL +++ +
Sbjct: 405 TAEQRLKIVKFIEFWTTSSHLVG----AFHGGGSPTAALITLRFLMDLSSREEAVK 456
>gi|126009177|ref|ZP_01709747.1| hypothetical protein Faci_03000382 [Ferroplasma acidarmanus fer1]
Length = 483
Score = 262 bits (669), Expect = 5e-68, Method: Composition-based stats.
Identities = 168/489 (34%), Positives = 261/489 (53%), Gaps = 10/489 (2%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
M E Y SL + VY+ G+R+EN HP + ++ + Y+L + +Y+++M T
Sbjct: 1 MNVESYKNSLNDGRV-VYYRGKRVENVAAHPALGVPVSHASGIYRLQQDSKYENMMCFTD 59
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQ--RCVGMDAFNAIYSTTYEMD 119
+GK + F + Q+TEDL + K+ + F + +G DA A+ + +D
Sbjct: 60 KESGK-ASIFYKIPQNTEDLVARHKLIYETTRLGRGQFNIVKAIGSDALFALMYVSRRID 118
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
T Y+ R + + +YV + DL + A TD KG+R L PSEQ DPD+Y+HIV+ ++GI
Sbjct: 119 SKYKTDYYNRVMAFYRYVVEKDLSLSLAQTDMKGNRSLRPSEQEDPDMYVHIVKRDKNGI 178
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMI-YGRQSCDTRK 238
VSGAKAH T ++ S+E +++PT M EAD DYAV+FA+P++ +G+ MI + +T
Sbjct: 179 YVSGAKAHTTQSIASNEIIVIPTRNMTEADKDYAVAFAIPANTKGITMIARPLKETETTM 238
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
+ + I N E E + +FD VF+P ERVF+ EY FAG++ F +HR +
Sbjct: 239 NDSLSVIGRENIEV---ETITIFDNVFIPMERVFLNGEYDFAGLLAMMFPTFHRFTAISY 295
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNY 358
+ + D LIG L A YNGV S+I+ L +I ETL A IA S T K +
Sbjct: 296 RAAMADFLIGTGKLLASYNGVDDKSNIRRNLAVLISYKETLKATAIASSYSCTYDKQASL 355
Query: 359 MI-DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGAT 417
I D++ NV K ++ + DIAGGL+ TMPS +DF + + KYLAG
Sbjct: 356 AIPDIIFTNVGKLFANENYTDVVKNIVDIAGGLVATMPSYEDFENSNEKTYLMKYLAGRK 415
Query: 418 GKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAI 477
+ T R+R+ + + ++ Y +H GS +A + + R D LA+
Sbjct: 416 KEETMERVRLFQTLREFISSLGSL-YLAGMIHAEGSIEASTMELCRSYDYSSSIDLAKFA 474
Query: 478 AHIDESLDK 486
+ I++ L+K
Sbjct: 475 SGINDKLEK 483
>gi|15920242|ref|NP_375911.1| hypothetical protein ST0063 [Sulfolobus tokodaii str. 7]
gi|15621024|dbj|BAB65020.1| 470aa long conserved hypothetical protein [Sulfolobus tokodaii str.
7]
Length = 470
Score = 250 bits (639), Expect = 1e-64, Method: Composition-based stats.
Identities = 160/485 (32%), Positives = 266/485 (54%), Gaps = 31/485 (6%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSM--NSVAMTYKLAEMDEYKHLMT 58
M + E Y++SL +V + G+ I N V+HP+++ S S Y D+ ++
Sbjct: 6 MRSKEDYLKSLND-GRRVMYRGKYISNIVEHPVLKISALHASKLFEYPDRSYDDQQY--- 61
Query: 59 ATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASC-----FQRCVGMDAFNAIYS 113
GK ++++ + ++++DL D+ +L+ T C + +G DA ++
Sbjct: 62 ------GK-ISKYFKVPKTSQDLLDR---HKLVYDTTIFCNGIFNISQAIGSDALFSLMI 111
Query: 114 TTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
T ++D+ G Y R +Y +YV NDL + A TD KGDR PS+Q DPDLY+ +V+
Sbjct: 112 TAKKLDKKYGKDYFSRVKKYYEYVVKNDLTLATAQTDVKGDRSKRPSKQPDPDLYVRVVD 171
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
VR DGIVV GAKAH T A + E +++PT AM E D DYA++FAVP++ G+ MI +
Sbjct: 172 VRNDGIVVRGAKAHTTQAAVADEIIVIPTRAMGEEDKDYAIAFAVPANTPGLKMIV--RP 229
Query: 234 CDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
D + + + + + E E L +FD VFVP +RVF+ +EY+FAG + FA YHR
Sbjct: 230 IDEIEGNSSSVLSVKDYEL---ETLTIFDNVFVPWDRVFLFREYEFAGTLARLFATYHRF 286
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ + + ++ +G+A L+A+ NG+ H++D +I++I E L IA SS ++
Sbjct: 287 TAISYRAAMANLYLGSAILSAEANGISNEKHVRDDIIDIILYKEILRMSAIA-SSVYPEI 345
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
+ + + N+ K +E+ + DIAGG++ T+PS++D + E G ++ KYL
Sbjct: 346 DEEIAIPNYIFTNIGKLYTNTHFHEVVKDLIDIAGGIISTLPSEEDLKSDE-GEVISKYL 404
Query: 414 AGATGKSTENRMRVLRLIENITLGTAAVGYRTESM-HGAGSPQAQRIMIARQGDLEGKKK 472
GA + R+ +L+ ++ I ++ VGY +M H GS +A +I + R D K+
Sbjct: 405 RGAI--DGKERIDILKFVKEIDGSSSLVGYWLTTMIHAEGSIEASKIELFRNYDFNESKE 462
Query: 473 LARAI 477
L + I
Sbjct: 463 LVKKI 467
>gi|70606878|ref|YP_255748.1| hydroxylase [Sulfolobus acidocaldarius DSM 639]
gi|68567526|gb|AAY80455.1| hydroxylase [Sulfolobus acidocaldarius DSM 639]
Length = 463
Score = 248 bits (632), Expect = 9e-64, Method: Composition-based stats.
Identities = 166/482 (34%), Positives = 265/482 (54%), Gaps = 26/482 (5%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T +++SLR KV++ G+ +E+ HP++ S+A + +++ EY M
Sbjct: 1 MRTKGDFLKSLRD-GRKVFYRGKPVEDITAHPIL-----SIAAIHA-SKLFEYSDRMYED 53
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASC-----FQRCVGMDAFNAIYSTT 115
+L +V++F ST+DL ++ +L+ T C + +G DA A+ T
Sbjct: 54 PSL--GKVSKFFKKPTSTQDLLER---HKLIYDTTMYCNGIFNISQAIGSDAIFALTITA 108
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
++D+ GT Y KR +Y +YV NDL + A TD KGDR PSEQADPD+Y+ IV+V+
Sbjct: 109 RQLDRKYGTDYTKRIQKYHEYVTKNDLTIATAQTDVKGDRSKRPSEQADPDMYVRIVDVK 168
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
DGIVV GAKAH T + S E +++PT AM+++D DYAV+FAVP++A G + +Y R D
Sbjct: 169 SDGIVVRGAKAHTTQSAVSDEIIVIPTRAMKDSDKDYAVAFAVPANAPG-LKLYVR-PID 226
Query: 236 TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
+ A + + E E + VFD VFVP +RVF+ KEY +AG + FA YHR +
Sbjct: 227 EIEGNTSAVLSKKDYEL---ETITVFDNVFVPWDRVFLFKEYDYAGNIAMLFATYHRFTA 283
Query: 296 GGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKA 355
+ + ++ +G+A + A NG+ H++D ++++I E L + I S+ M
Sbjct: 284 LSYRSALINLFLGSARVMAKANGIENEKHVRDDVVDLILYKEILRSTAIT-SAISPVMLE 342
Query: 356 GNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
G + + L NV K +++ + D+AGG++ T+PSQ+DF E G + KYL G
Sbjct: 343 GVAVPNPLYVNVGKLYSNMHFHDVIKDLVDVAGGIIATLPSQEDFDSEE-GKTIIKYLRG 401
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLAR 475
A E R+++L+L++ + A T +H GS +A +I + R D + L +
Sbjct: 402 AV--DGEERVKILKLVKELAASPVAGYLLTAMVHAEGSIEASKIELFRSYDYREAESLIK 459
Query: 476 AI 477
I
Sbjct: 460 KI 461
>gi|146303989|ref|YP_001191305.1| Vinylacetyl-CoA Delta-isomerase [Metallosphaera sedula DSM 5348]
gi|145702239|gb|ABP95381.1| Vinylacetyl-CoA Delta-isomerase [Metallosphaera sedula DSM 5348]
Length = 459
Score = 228 bits (582), Expect = 5e-58, Method: Composition-based stats.
Identities = 163/484 (33%), Positives = 267/484 (55%), Gaps = 35/484 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M + E++V LR KV++ G+ I+ P +HP+I+ VA+++ +++ EY
Sbjct: 1 MRSKEEFVNGLRD-KRKVFYRGKLID-PTEHPIIK-----VAVSHA-SKLFEYP----GR 48
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASC-----FQRCVGMDAFNAIYSTT 115
+ GK ++F H+ ++++DL ++ L+ T C + +G DA A+ T+
Sbjct: 49 VDQEGK--SKFFHVPRNSQDLMER---HGLIYGLTMYCNGIFNISQAIGSDALFALLITS 103
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
+D+ GT Y KR Y+ +V+D DL + A TD KGDR P EQ DPD+YL + EVR
Sbjct: 104 RRVDRERGTDYTKRVENYLTHVRDKDLTIATAQTDVKGDRSKRPKEQGDPDMYLRVKEVR 163
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
DGIVV GAKAH T A S E +++PT AMRE + +YAV+FAVP++ +G+ M Y R D
Sbjct: 164 SDGIVVRGAKAHTTQAAVSDEIIVIPTRAMREEEKEYAVAFAVPANTQGLRM-YVR-PID 221
Query: 236 TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
+ A + + E E L VFD VFVP +RVF+ +E +FAG + FA +HR +
Sbjct: 222 ELEGNSSAVLSRQDYEL---ETLTVFDDVFVPWDRVFLFQESKFAGQLATLFATFHRFTA 278
Query: 296 GGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKA 355
+V ++ +GAA LA+ NG+ ++D +++MI E + A ++ + ++
Sbjct: 279 LSYRVATANLFLGAARLASFVNGIQNEKQVRDDIVDMIMYKEVMRATALSAAMSPV-IEE 337
Query: 356 GNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
G + + + NV K +++ R D++GG++ TMPS++D E + KYL G
Sbjct: 338 GVAIPNPVFTNVGKLYSNAHFHDVVRDLIDVSGGIIATMPSEEDLTG-EGREEIMKYLRG 396
Query: 416 ATGKSTENRMRVLRLIENITLGTAA-VGY-RTESMHGAGSPQAQRIMIARQGDLEGKKKL 473
A + R +VL++ + LG++ GY T +H GS +A +I + R D +KL
Sbjct: 397 AV--DGKERTQVLKIAKE--LGSSNFTGYILTLMIHAEGSMEASKIELYRGYDFSDSEKL 452
Query: 474 ARAI 477
+++
Sbjct: 453 VKSL 456
>gi|15899242|ref|NP_343847.1| 4-hydroxybutyryl-CoA dehydratase (abfD-1) [Sulfolobus solfataricus
P2]
gi|13815806|gb|AAK42637.1| 4-hydroxybutyryl-CoA dehydratase (abfD-1) [Sulfolobus solfataricus
P2]
Length = 463
Score = 228 bits (582), Expect = 6e-58, Method: Composition-based stats.
Identities = 153/479 (31%), Positives = 257/479 (53%), Gaps = 20/479 (4%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M + E +++SL+ +Y+ G+ +E+ H +++ + A Y+ A+
Sbjct: 1 MRSKEDFLKSLKD-GRNLYYRGKLVEDITTHQILKTAALHAAKLYEYADR-------VYE 52
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQ--RCVGMDAFNAIYSTTYEM 118
N GK +++F + +++DL D+ K+ + F + +G DA A+ T ++
Sbjct: 53 DNKMGK-MSKFFKVPWTSQDLLDRHKLIYDLTMYCNGVFNISQAIGSDAIFALMITAKQV 111
Query: 119 DQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
D+ GT Y KR +Y + V DL + A TD KGDR PSEQ DPD+Y+ +V+V+ DG
Sbjct: 112 DRKYGTDYSKRVEKYFERVAKEDLTLATAQTDVKGDRSKRPSEQVDPDMYVRVVDVKSDG 171
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IVV GAKAH T + S E +++PT MR++D DYAV+FAVP++ +G+ M Y R +
Sbjct: 172 IVVRGAKAHTTQSAVSDEIIVIPTRVMRDSDKDYAVAFAVPANTKGLKM-YIRP---IDE 227
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
+E + L ++ E L VF+ VFVP +RVF+ KEY +AG + FA +HR +
Sbjct: 228 IEGNSSSVLSRKDY-ELETLTVFNDVFVPWDRVFLFKEYDYAGTLAMLFATFHRFTALSY 286
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNY 358
+ ++ +GA+ +A+ NG+ H++D ++++I E + + IA + M+ G
Sbjct: 287 RSATMNLYLGASKVASQVNGIENEKHVRDDIVDIILYKEIMRSSAIAAAVYPVNME-GIA 345
Query: 359 MIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATG 418
+ + L NV K +++ R DIAGG++ TMPSQ+D E G + KYL G+
Sbjct: 346 VPNPLFTNVGKLYSNMHFHDVVRDLIDIAGGIIATMPSQEDLESDE-GKNIVKYLRGSV- 403
Query: 419 KSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAI 477
E R +VL+L + + T T +H GS +A +I + R + + + L + +
Sbjct: 404 -DGEERAKVLKLAKELGASTFTGYLLTGMIHAEGSMEASKIELFRSYNFKEAENLVKRV 461
>gi|55980929|ref|YP_144226.1| 4-hydroxyphenylacetate-3-hydroxylase [Thermus thermophilus HB8]
gi|55772342|dbj|BAD70783.1| 4-hydroxyphenylacetate-3-hydroxylase [Thermus thermophilus HB8]
Length = 481
Score = 154 bits (389), Expect = 1e-35, Method: Composition-based stats.
Identities = 121/453 (26%), Positives = 211/453 (46%), Gaps = 30/453 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T +Y+E+L+ +++ GE++E+P HP+ R + ++A Y L Y+ ++T
Sbjct: 4 TGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEE 63
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
GK+ + ++ EDLK + + +L + +GM + Y M A
Sbjct: 64 --GKRHGMSFLIPKTKEDLKRRGQAYKLWADQN-------LGMMGRSPDYLNAVVMAYAA 114
Query: 123 GTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
Y F E Y +Y++D DL A+T+P+ +R PS Q DP + + +V+ E G
Sbjct: 115 SADYFGEFAENVRNYYRYLRDQDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKG 174
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IVV GA+ T + + E LI P+ ++ YA++FA+P+ G+ + R+
Sbjct: 175 IVVRGARMTATFPL-ADEVLIFPSTLLQAGSEKYALAFALPTSTPGLHFV-------CRE 226
Query: 239 MEEGADIDLG---NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
G D +S + LV+FD V VP ERVF+ + + ++
Sbjct: 227 ALVGGDSPFDHPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAH 286
Query: 296 G--GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
K + +G AAL A+ G H+++K+ E+I E + A E +
Sbjct: 287 QVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKEN 346
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
G + D + + RL I + E I ++T+PS++DF+ P +GP ++K+L
Sbjct: 347 AYGLLVPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGP-LGPFLEKFL 405
Query: 414 AGATGKSTENRMRVLRLIENITLGTAAVGYRTE 446
GA ++ E R+ + RL ++TL + G R E
Sbjct: 406 QGAALEAKE-RVALFRLAWDMTL--SGFGARQE 435
>gi|46198902|ref|YP_004569.1| 4-hydroxyphenylacetate 3-monooxygenase [Thermus thermophilus HB27]
gi|46196526|gb|AAS80942.1| 4-hydroxyphenylacetate 3-monooxygenase [Thermus thermophilus HB27]
Length = 481
Score = 153 bits (386), Expect = 3e-35, Method: Composition-based stats.
Identities = 121/453 (26%), Positives = 210/453 (46%), Gaps = 30/453 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T +Y+E+L+ +++ GE++E+P HP+ R + ++A Y L Y+ ++T
Sbjct: 4 TGAEYIEALKTRPPNLWYKGEKVEDPTTHPVFRGIVRTMAALYDLQHDPRYREVLTYEEE 63
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
GK+ + ++ EDLK + + +L + +GM + Y M A
Sbjct: 64 --GKRHGMSFLIPKTKEDLKRRGQAYKLWADQN-------LGMMGRSPDYLNAVVMAYAA 114
Query: 123 GTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
Y F E Y +Y++D DL A+T+P+ +R PS Q DP + + +V+ E G
Sbjct: 115 SADYFGEFAENVRNYYRYLRDKDLATTHALTNPQVNRARPPSGQPDPYIPVGVVKQTEKG 174
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
IVV GA+ T + + E LI P+ ++ YA++FA+P+ G+ + R+
Sbjct: 175 IVVRGARMTATFPL-ADEVLIFPSTLLQAGSEKYALAFALPTSTPGLHFV-------CRE 226
Query: 239 MEEGADIDLG---NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
G D +S + LV+FD V VP ERVF+ + + ++
Sbjct: 227 ALVGGDSPFDYPLSSRVEEMDCLVIFDDVLVPWERVFILGNVELCNNAYAATGALNHMAH 286
Query: 296 G--GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
K + +G AAL A+ G H+++K+ E+I E + A E +
Sbjct: 287 QVVALKTAKTEAFLGVAALMAEGIGADVYGHVQEKIAEIIVYLEAMRAFWTRAEEEAKEN 346
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
G D + + RL I + E I ++T+PS++DF+ P +GP ++K+L
Sbjct: 347 AYGLLCPDRGALDGARNLYPRLYPRIREILEQIGASGLITLPSEKDFKGP-LGPFLEKFL 405
Query: 414 AGATGKSTENRMRVLRLIENITLGTAAVGYRTE 446
GA ++ E R+ + RL ++TL + G R E
Sbjct: 406 QGAALEAKE-RVALFRLAWDMTL--SGFGARQE 435
>gi|108804686|ref|YP_644623.1| 4-hydroxyphenylacetate 3-hydroxylase [Rubrobacter xylanophilus DSM
9941]
gi|108765929|gb|ABG04811.1| 4-hydroxyphenylacetate 3-hydroxylase [Rubrobacter xylanophilus DSM
9941]
Length = 483
Score = 142 bits (359), Expect = 4e-32, Method: Composition-based stats.
Identities = 132/493 (26%), Positives = 224/493 (45%), Gaps = 20/493 (4%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT ++Y ESL +VY GE++EN +H + +P ++ A Y + Y T T
Sbjct: 3 LMTGDEYRESLND-GREVYVDGEKVENVAEHLVFKPIVDVKARMYDMNHEARYADTCTYT 61
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G + R L + EDL + + R VG + ++S D+
Sbjct: 62 LP-DGDTICRAFKLPKEKEDLAAIRRYVETVLDDIGGVVYR-VGDETIGELWSLYDAQDK 119
Query: 121 --ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
+ Y + +++ V DL A TDPKGDR P EQ DPD+ LH+V+ ++G
Sbjct: 120 LNEIDPAYAENIRRHVERVPKLDLFHVSANTDPKGDRSKPPEEQ-DPDMLLHVVDENDNG 178
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIA--MREADADYAVSFAVPSDAEGVIMIYGRQSCDT 236
IVV GAK ++T A +H+ + PTIA E+ A YA F +A G+ + C +
Sbjct: 179 IVVRGAK-YETAAAYAHQAFVKPTIANWTDESMAPYACGFICEMNAPGL-----KHLCRS 232
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
+ D ++ F + L++FD V +P E V + + A + Y +Y
Sbjct: 233 SLGKGANPTDYPMSTRFDEIDTLLIFDNVLIPWENVLFHRSIESAQYIRATLHRYSAFNY 292
Query: 296 GGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKA 355
+ D+L+G A L + G+ K +K+KL ++I ET+ A A +E + +
Sbjct: 293 VLRVLRRADLLLGTALLNVEQTGLTKIPAVKEKLAQLIGYRETINAHLTAAVAEAQESPS 352
Query: 356 GNYMIDLLLANVCK-QNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLA 414
G M + L + +T P +A L ++ GG + P + P I + KY +
Sbjct: 353 GLMMPNQSLLYTGRVYALTNFP-AMAHLTRELVGGQLAVTPDAKTVADPRIKGYIDKYYS 411
Query: 415 GATGKSTENRMRVLRLIENITLGTAAVGYR-TESMHGAGSPQAQRIMIARQGDLEGKKKL 473
G S+E+R ++L ++ L ++ G++ T + P AQ + I D E +++
Sbjct: 412 -VGGWSSEDRTKLLYFARDL-LNSSYAGHKITFELFAQSPPFAQNLAIYNNFDPEPAREM 469
Query: 474 ARAIAHIDESLDK 486
R A++ + K
Sbjct: 470 VRKAANLSPKVLK 482
>gi|111018781|ref|YP_701753.1| probable 4-hydroxyphenylacetic hydroxylase [Rhodococcus sp. RHA1]
gi|110818311|gb|ABG93595.1| probable 4-hydroxyphenylacetic hydroxylase [Rhodococcus sp. RHA1]
Length = 486
Score = 141 bits (356), Expect = 1e-31, Method: Composition-based stats.
Identities = 135/491 (27%), Positives = 226/491 (46%), Gaps = 20/491 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T ++Y ES+R +V+ GER+++ DHPM +P + A Y LA + + MT
Sbjct: 4 TGDEYRESIRD-GREVWVDGERVKDVADHPMFKPIVEVRARIYDLAHEEATQDAMTYVDP 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
+G++ L ++ +D DK L+ T R VG + ++S ++ L
Sbjct: 63 ESGERNAIANKLPRTQQDWLDKRAAVDLVLGDTRGVVTR-VGDETIGEMWSL-FDGQDVL 120
Query: 123 GTTYHKRFIEYMKYVQDNDLVVD----GAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
RF E ++ D + D A TDPKGDR +P +Q DPD+ LH+V+ ++G
Sbjct: 121 NEV-DPRFSENIRRHLDRSVREDPFHVSANTDPKGDRSKAPQDQ-DPDMLLHVVKETDNG 178
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAM--READADYAVSFAVPSDAEGVIMIYGRQSCDT 236
IVV GAK ++T A S++ PTIA +DYAV F + A G+ I R
Sbjct: 179 IVVRGAK-YETAAAYSNQAFTKPTIANWGNSELSDYAVGFVLDMGAPGLKYI-SRNGFAG 236
Query: 237 RKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYG 296
R AD L N E+LVVFD V +P E V + + A + Y +
Sbjct: 237 RA--PSADYPLAN-RVDEVESLVVFDNVEIPWEDVLFYRHTRAATFIRSTLHRYSAFPFV 293
Query: 297 GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
+ + D++IG+A +G+ K +++KL ++ ET+ A A S G
Sbjct: 294 QRTLHLADLMIGSALWNVKQSGLEKQQAVQEKLAQLACYRETINAHLTAAISLAEPSPGG 353
Query: 357 NYMIDLLLANVCK-QNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
M + L + +++LP + +A ++ GG + P F P++ P ++K+ +
Sbjct: 354 LLMPNQSLLYTGRVMALSQLP-AMMHIARELCGGQICITPDAATFADPDVAPWLEKFYSI 412
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYR-TESMHGAGSPQAQRIMIARQGDLEGKKKLA 474
++R ++L ++ L + G+R T + P AQ + R D +G L
Sbjct: 413 NDNWVADDRRKLLAFARDL-LNSDYAGHRLTFQLFAQSPPFAQLAAVYRNFDFDGPLGLV 471
Query: 475 RAIAHIDESLD 485
+A A + ++D
Sbjct: 472 KAAAGLSNNVD 482
>gi|118477510|ref|YP_894661.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus thuringiensis str.
Al Hakam]
gi|118416735|gb|ABK85154.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus thuringiensis str.
Al Hakam]
Length = 514
Score = 136 bits (343), Expect = 3e-30, Method: Composition-based stats.
Identities = 112/437 (25%), Positives = 205/437 (46%), Gaps = 18/437 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T EQY+E LRK N +++ G ++ + V+ + R + +A Y + EY+ +T
Sbjct: 29 TGEQYIEGLRKRNPEIWIGGRKVTDVVNEDVFREPIIQIANLYDMQHNPEYQDKITHICE 88
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD--- 119
TG++V+ + ++ EDLK + ++ + + T R D N ++
Sbjct: 89 ETGERVSNAFLVPRNYEDLKVRRELFEVWAKATYGLMGRTP--DFLNVTVTSMASNSWFF 146
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ + Y K+++DNDL + A+ +P+ DR + +Q D ++L +V +G+
Sbjct: 147 EKFNPEWGANIKNYYKHIRDNDLFLTHAIINPQNDRSKASHQQEDETMHLGVVSETAEGM 206
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T A + E +I + + D +A+SFAVP DA G+ R C M
Sbjct: 207 YVSGAKMLATLAPITDEVIIYSYPSFKPGDERHAISFAVPIDAPGL-----RILC-REPM 260
Query: 240 EEGA----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
++G D L S F +AL+VF VF+P ++VF+ + + + + H+ ++
Sbjct: 261 QDGKRSLFDHPLA-SRFEEMDALLVFHNVFIPWDKVFIYQSVEAGNQLYPKTGIGHQPAH 319
Query: 296 GGCKVGVGDVLIGA--AALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
G+ + A A AD GV +++++L E++ ET+ A E
Sbjct: 320 QSGVRGLVKLSFAAEVAMKLADSIGVDGFLNVQNQLAELMQDVETIRALLQVAEYEYETN 379
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
G + L + + + ++ + + I G ++ P+ DF +PEI ++KY
Sbjct: 380 SYGEVIPARLPLDTIRSLLPKMYPRAIEIIQTIGAGGLLMSPTGADFMNPEIHDDMQKYY 439
Query: 414 AGATGKSTENRMRVLRL 430
G G S+E R+R+ +L
Sbjct: 440 IGREGVSSEERVRLFKL 456
>gi|42781214|ref|NP_978461.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus cereus ATCC 10987]
gi|42737136|gb|AAS41069.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus cereus ATCC 10987]
Length = 490
Score = 136 bits (342), Expect = 3e-30, Method: Composition-based stats.
Identities = 112/437 (25%), Positives = 203/437 (46%), Gaps = 18/437 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T EQY+E LRK N +++ G ++ + V+ + R + +A Y + EY+ +T
Sbjct: 5 TGEQYIEGLRKRNPEIWIGGRKVTDVVNEDVFREPILQIANLYDMQHHPEYQDKITHICE 64
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD--- 119
TG++V+ + ++ EDLK + ++ + + T R D N ++
Sbjct: 65 ETGERVSNAFLVPKNYEDLKARRELFEVWAKATFGLMGRTP--DFLNVTVTSMASNSWFF 122
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ + Y K+++DNDL + A+ +P+ DR + Q D ++L +V +G+
Sbjct: 123 EKFNPEWGANIKNYYKHIKDNDLFLTHAIINPQNDRSKASHXQEDETMHLGVVSETAEGM 182
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T A + E +I + + D +A+SFAVP DA G+ R C M
Sbjct: 183 YVSGAKMLATLAPITDEVIIYSYPSFKPGDERHAISFAVPIDAPGL-----RVLC-REPM 236
Query: 240 EEGA----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
++G D L S F +AL+VF VF+P ++VF+ + + + + H+ ++
Sbjct: 237 QDGKRSLFDHPLA-SRFEEMDALLVFHNVFIPWDKVFIYQSVEAGNQLYPKTGIGHQPAH 295
Query: 296 GGCKVGVGDVLIGA--AALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
G+ + A A AD GV +++++L E++ ET+ A E
Sbjct: 296 QSGVRGLVKLSFAAEVAMKVADSIGVDGFLNVQNQLAELMQDVETIRALLQVAEYEYETN 355
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYL 413
G + L + + + ++ + + I G ++ P+ DF PEI ++KY
Sbjct: 356 SYGEVIPARLPLDTIRSLLPKMYPRAIEIIQTIGAGGLLMSPTGADFMTPEIQDDMQKYY 415
Query: 414 AGATGKSTENRMRVLRL 430
G G S+E R+R+ +L
Sbjct: 416 IGREGVSSEERVRLFKL 432
>gi|71281564|ref|YP_268775.1| 4-hydroxyphenylacetate-3-hydroxylase family protein [Colwellia
psychrerythraea 34H]
gi|71147304|gb|AAZ27777.1| 4-hydroxyphenylacetate-3-hydroxylase family protein [Colwellia
psychrerythraea 34H]
Length = 509
Score = 134 bits (336), Expect = 2e-29, Method: Composition-based stats.
Identities = 133/491 (27%), Positives = 221/491 (45%), Gaps = 23/491 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T E+Y ES++ +VY G+++++ HP +P ++ + Y + K +MT ++
Sbjct: 4 TGEEYRESIKD-GREVYIEGDKVKDVATHPAFKPIIDVRSKIYDMQHSASTKDVMTYKAD 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
++ L +S +D +K +M + R VG + ++S Y+ AL
Sbjct: 63 -NSEECAIALKLPRSQQDWWNKKNATEVMMNEIGGVVTR-VGDETAGEMWSL-YDAQTAL 119
Query: 123 GTTYHKRFIEYMKYVQDNDLVVD----GAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
+ F + +K DN ++ D A TDPKGDR P Q DPD+ LH+V + G
Sbjct: 120 NEV-NPEFADNIKNHIDNIVINDPFHVTANTDPKGDRSKPPQAQ-DPDMLLHVVRETDRG 177
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREAD---ADYAVSFAVPSDAEGVIMIYGRQSC- 234
IVV GAK +T A +++ PTIA AD +DYAV F + G+ +I C
Sbjct: 178 IVVRGAK-FETAAAYANQAFTKPTIANWTADTKFSDYAVGFICDLGSAGIKII-----CR 231
Query: 235 DTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQS 294
D + D + ++F EALVVF+ V +P E V + + A + Y +
Sbjct: 232 DGFAGKNPLDYPIA-TKFDEVEALVVFNDVEIPWENVLFYRNTKAAMFIRSTLHRYSAFA 290
Query: 295 YGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMK 354
Y + V ++LIGA+ L G ++++L ++ E + A I+ + +
Sbjct: 291 YIQRNLKVAELLIGASILNVQQTGTDNQPAVQERLAKLACYREGIDAHLISSIAMAEESP 350
Query: 355 AGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLA 414
G M + L + YE+ +A ++ GG + PS F H EI P + K+ +
Sbjct: 351 GGLTMPNQSLLYAGRVFACSQLYEMVNIARELGGGQVCLTPSFDTFNHKEIKPWLDKFYS 410
Query: 415 GATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQ-AQRIMIARQGDLEGKKKL 473
S E+R ++L ++ A G+R A SP+ A + D +G L
Sbjct: 411 LNDQWSAEDRRKLLAYSRDLCNSDYA-GHRLTFQEFAQSPRFAHLASVYHHFDFDGPIDL 469
Query: 474 ARAIAHIDESL 484
R A + ESL
Sbjct: 470 VRQAAGLSESL 480
>gi|56421569|ref|YP_148887.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus kaustophilus
HTA426]
gi|56381411|dbj|BAD77319.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus kaustophilus
HTA426]
Length = 492
Score = 133 bits (334), Expect = 3e-29, Method: Composition-based stats.
Identities = 113/461 (24%), Positives = 204/461 (44%), Gaps = 42/461 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T ++Y+E L++ VY GE++E+ HP R + S+A Y K L + +
Sbjct: 5 TGQEYMERLKRAKSSVYIHGEKVEDVTVHPAFRNVVRSMAALYDRQYEKPEKMLYRSPTT 64
Query: 63 -----LTGKQVNRFCHLHQSTEDLKDKVKMQR-LMGQKTASCFQRCVGMDAFNAIYSTTY 116
+T Q L E ++ +M +MG+ + M N +++
Sbjct: 65 GQFVGMTFIQPTTIDELIARREATQEWARMSAGMMGRSPDYLNAEVMAMGVANDLFAEDD 124
Query: 117 EMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
M + + Y +Y ++ND+ + + P+ +R + EQ D D+ LH+VE R+
Sbjct: 125 PM-------FAENAKNYYEYARENDISLTHTLIHPQMNRAKALHEQKDADVPLHLVERRK 177
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIMI------ 228
DGI+VSG + T + E L+ P+ + + YA++FA+P++ GV I
Sbjct: 178 DGIIVSGIRLLATQGGITDEILVFPSTVKKSTAGEDPYALAFAIPNNTPGVKFICREAFD 237
Query: 229 YGRQSCD---TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVE 285
YGR + D + EEG +A+V F+ VFVP ERVF+C
Sbjct: 238 YGRSAWDHPLASRFEEG-------------DAIVSFENVFVPWERVFVCGNSSICNRTFR 284
Query: 286 RFAGYHRQSYGGCKVGV--GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACG 343
S+ + + L+G + G+ + H+KDK E++ + ET+ +
Sbjct: 285 ETNAVIHMSHQVVAKNIVKTEFLLGVTLCLIEAIGIGEFQHVKDKGAEIMLVLETMKSHL 344
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHP 403
+ + G D + + R+ ++ + + ++ +P++ DF H
Sbjct: 345 YRAEHNAKRDRWGTMTPDFAALDAARNWYPRIYPRLSEIIRILGASGLMAIPTEADFHHE 404
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYR 444
EIG IV++ + GAT E R+++ RL ++T+ +A G R
Sbjct: 405 EIGDIVRRAMQGATVDGYE-RVQLFRLAWDLTM--SAFGAR 442
>gi|138896629|ref|YP_001127082.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus
thermodenitrificans NG80-2]
gi|134268142|gb|ABO68337.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus
thermodenitrificans NG80-2]
Length = 492
Score = 132 bits (331), Expect = 7e-29, Method: Composition-based stats.
Identities = 115/461 (24%), Positives = 202/461 (43%), Gaps = 42/461 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTY--KLAEMDEYKHLMTAT 60
T QY+E L++ VY GE++E+ HP R + S+A Y + + D+ + T
Sbjct: 5 TGNQYMERLKQAKSSVYIHGEKVEDVTVHPAFRNVVRSMAALYDRQYEKPDKMLYRSPTT 64
Query: 61 SNLTGK---QVNRFCHLHQSTEDLKDKVKMQR-LMGQKTASCFQRCVGMDAFNAIYSTTY 116
L G Q L E ++ +M +MG+ + M N +++
Sbjct: 65 GQLVGMTFIQPTTIDELIARREATQEWARMSAGMMGRSPDYLNAEVMAMGIANDLFAEDD 124
Query: 117 EMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
M + + Y +Y ++ND+ + + P+ +R + EQ D D+ LH+VE R+
Sbjct: 125 PM-------FAENARNYYEYARENDISLTHTLIHPQMNRAKALHEQKDADVPLHLVERRK 177
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIMI------ 228
DGI+VSG + T + E L+ P+ + + YA++FA+P++ GV I
Sbjct: 178 DGIIVSGIRLLATQGGITDEILVFPSTVKKSTAGEDPYALAFAIPNNTPGVKFICREAFD 237
Query: 229 YGRQSCD---TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVE 285
YGR + D + EEG +A+V F+ VFVP ERVF+C
Sbjct: 238 YGRSTWDHPLASRFEEG-------------DAIVSFENVFVPWERVFVCGNSSICNRTFR 284
Query: 286 RFAGYHRQSYGGCKVGV--GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACG 343
S+ + + L+G + G+ + H+KDK E++ ET+ +
Sbjct: 285 ETNAVVHMSHQVVAKNIVKTEFLLGVTLCLIEAIGIGEFQHVKDKGAEIMLALETMKSHL 344
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHP 403
+ G D + + R+ + + + ++ +P++ DF H
Sbjct: 345 YRAEHNAKPDRWGTMTPDFAALDAARNWYPRVYPRLVEIIRILGASGLMAIPTEADFEHE 404
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYR 444
EIG IV++ + GAT E R+++ RL ++T+ +A G R
Sbjct: 405 EIGDIVRRAMQGATVDGYE-RVQLFRLAWDLTM--SAFGAR 442
>gi|152974775|ref|YP_001374292.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit [Bacillus
cereus subsp. cytotoxis NVH 391-98]
gi|152023527|gb|ABS21297.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit [Bacillus
cereus subsp. cytotoxis NVH 391-98]
Length = 490
Score = 131 bits (330), Expect = 1e-28, Method: Composition-based stats.
Identities = 118/450 (26%), Positives = 210/450 (46%), Gaps = 18/450 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIE-NPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T ++Y+E + + N V+ G+R+E N +HP + M + A Y + E MT TS
Sbjct: 5 TGKEYIERVDQANANVWIDGKRVEGNISEHPAFKGVMKTQAELYDMQHDPEKAEYMTYTS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNA---IYSTTYEM 118
+G++V ++ EDL + KM + + R D NA Y + EM
Sbjct: 65 PTSGERVGTSFLQPKTKEDLAKRRKMIQEWAKYNGGMMGR--SPDYINAGMMAYGSAAEM 122
Query: 119 DQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
Y K EY +Y ++NDL + + P+ +R ++ S+ +DP + IVE +G
Sbjct: 123 FGKQDAFYAKNMAEYYEYCRENDLSLTHTLIQPQVNRAVNASQLSDPYIAARIVEKTSEG 182
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIMIYGRQSCDT 236
+V+ GA+ T + E ++ P+ +++++ + YA +F++P+ G+ I R+S D
Sbjct: 183 VVIRGARLLATQGGITDEIMVFPSTLLKQSEEENPYAYAFSIPNHTPGLKFIC-RESFDY 241
Query: 237 RKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMV-ERFAGYHRQSY 295
K D LG S F + +VVFD V VP RVF + E A H
Sbjct: 242 GKSH--FDHPLG-SRFEEMDTIVVFDDVVVPWNRVFALGDVGVCNQAYNESNAVVHMTHQ 298
Query: 296 GGCK-VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMK 354
K + + ++G L + + + H+++K+ E+I ET+ A A + K
Sbjct: 299 VVSKNIAKTEFVLGILQLMVETINIGQFQHVQEKMSEVIMALETVKAYVTAAEANAKLDK 358
Query: 355 AGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLA 414
G D NV + ++ + + + + ++ +PS+ DF+ E+ P + KYL
Sbjct: 359 WGIMTPDFTPLNVARHYYPKIYPRFSEIMQLLGASGLMAIPSESDFQ-SELRPDLDKYLQ 417
Query: 415 GATGKSTENRMRVLRLIENITLGTAAVGYR 444
A G + NR+++ RL ++ + +A G R
Sbjct: 418 AANGDAY-NRVKLYRLAWDVCM--SAFGTR 444
>gi|47498588|gb|AAT28189.1| 4-hydroxyphenylacetic acid 3-hydroxylase [Geobacillus sp. PA-9]
Length = 494
Score = 131 bits (329), Expect = 1e-28, Method: Composition-based stats.
Identities = 113/461 (24%), Positives = 205/461 (44%), Gaps = 42/461 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T ++Y+E L++ VY GE++E+ HP R + S+A Y K L + +
Sbjct: 7 TGKEYMERLKQAKSSVYIHGEKVEDVTVHPAFRNVVRSMAALYDRQYEKPEKMLYRSPTT 66
Query: 63 -----LTGKQVNRFCHLHQSTEDLKDKVKMQR-LMGQKTASCFQRCVGMDAFNAIYSTTY 116
+T Q L E ++ +M +MG+ + M N +++
Sbjct: 67 GQPVGMTFIQPTTIDELIARREATQEWARMSAGMMGRSPDYLNAEVMAMGIANDLFAEDD 126
Query: 117 EMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
M + + Y +Y +++D+ + + P+ +R + EQ D D+ LH+VE R+
Sbjct: 127 PM-------FAENAKNYYEYAREHDISLTHTLIHPQMNRAKALHEQNDADVPLHLVERRK 179
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIMI------ 228
DGI+VSG + T + E L+ P+ + + YA++FA+P++ GV I
Sbjct: 180 DGIIVSGIRLLATQGGITDEILVFPSTVKKATSGEDPYALAFAIPNNTPGVKFICREAFD 239
Query: 229 YGRQSCD---TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVE 285
YGR + D + EEG +A+V F+ VFVP ERVF+C
Sbjct: 240 YGRSAWDHPLASRFEEG-------------DAIVSFENVFVPWERVFVCGNSSICNRTFR 286
Query: 286 RFAGYHRQSYGGCKVGV--GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACG 343
S+ + + L+G + G+ + H+KDK E++ + ET+ +
Sbjct: 287 ETNAVVHMSHQVVAKNIVKTEFLLGVTLCLIEAIGIGEFQHVKDKGAEIMLVLETMKSHL 346
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHP 403
+ + G D + + R+ +A + + ++ +P++ DF+H
Sbjct: 347 YRAEHNAKRDRWGTMTPDFAALDAARNWYPRIYPRLAEIIRILGASGLMAIPTEADFQHE 406
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYR 444
EIG IV++ + GAT E R+++ RL ++T+ +A G R
Sbjct: 407 EIGDIVRRAMQGATVDGYE-RVQLFRLAWDLTM--SAFGAR 444
>gi|138896797|ref|YP_001127250.1| Putative aromatic compound hydroxylase [Geobacillus
thermodenitrificans NG80-2]
gi|134268310|gb|ABO68505.1| Putative aromatic compound hydroxylase [Geobacillus
thermodenitrificans NG80-2]
Length = 494
Score = 131 bits (329), Expect = 1e-28, Method: Composition-based stats.
Identities = 116/442 (26%), Positives = 205/442 (46%), Gaps = 28/442 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T QY+ L+ +++ G R+ N + P+ + + +A Y + EY+ +T
Sbjct: 7 TGAQYISGLKSRKPEIWLSGRRVINVCEEPVFKQPIREIARLYDMQHDPEYQDKITHICT 66
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
TG++V+ + +S EDL + + + + T R D N + ++ Y + +
Sbjct: 67 ETGERVSNAFLVPKSREDLLARRALFEVWARATFGLMGRTP--DFLNVVLTSLYS-NASF 123
Query: 123 GTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
Y+ ++ E Y +YV+DNDL + A+ +P+ DR EQ D +L +V +G
Sbjct: 124 LEKYNPQWAENIRAYYRYVRDNDLFLTHAIINPQNDRSKPSHEQQDTFTHLGVVRETPEG 183
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
++V GAK T A + E +I + D YAVSFA+P D G+ R C
Sbjct: 184 LIVRGAKMLATLAPITDEVIIYTFPGYKPGDERYAVSFAIPIDTPGL-----RILC-REP 237
Query: 239 MEEGA----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQS 294
M++G D L S F +AL+VF+ V VP +RVF+ + A ++ + + +
Sbjct: 238 MQDGTRPLFDHPLA-SRFEEMDALLVFNDVLVPWDRVFIYNNVEAANLLYPKTGIAQQPA 296
Query: 295 YGGCKVGVGDVL-----IGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSE 349
+ + GV ++ A AD GV ++++ L E++ E + A E
Sbjct: 297 H---QTGVRGLIKLQFATEVAIRLADSIGVDVYLNVQNDLGELLQSVEAIRALLHLAEHE 353
Query: 350 GTQMKAGNYMIDLLLANVCKQNITRL-PYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPI 408
+ +G M + + + +L P + L AGGL+++ P+ DF +PE+
Sbjct: 354 LEVLPSGEVMPGWVPLETIRGLLPKLYPRAVEVLQIIGAGGLLMS-PTGADFANPELAAD 412
Query: 409 VKKYLAGATGKSTENRMRVLRL 430
++KY AG G E R+R+ +L
Sbjct: 413 MEKYYAGRIGVGGEERVRLFKL 434
>gi|23100327|ref|NP_693794.1| 4-hydroxyphenylacetate-3-hydroxylase [Oceanobacillus iheyensis
HTE831]
gi|22778559|dbj|BAC14828.1| 4-hydroxyphenylacetate-3-hydroxylase [Oceanobacillus iheyensis
HTE831]
Length = 498
Score = 128 bits (321), Expect = 1e-27, Method: Composition-based stats.
Identities = 108/448 (24%), Positives = 208/448 (46%), Gaps = 26/448 (5%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T +QY++ L+K N VY GER+E+ HP + ++ S+A Y L E M TS
Sbjct: 5 TGQQYIDKLKKANNNVYIHGERVEDVTTHPAFKGAVQSMAKLYDLQY--EKPEKMLYTSP 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVK--------MQRLMGQKTASCFQRCVGMDAFNAIYST 114
TG +V++ ++ E+L ++ + + LMG+ + M+ Y
Sbjct: 63 TTGDKVSKTFMAPETIEELIERREAIMEWQGITKGLMGRSPDYLNSEVMTMEKAYDYYGK 122
Query: 115 TYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEV 174
+ + + + +Y +Y ++ND+ + + P+ +R +EQ D ++ LH+VE
Sbjct: 123 SNSL-------FAENAKKYAEYARENDISLTHTLIHPQVNRAKIQAEQKDANVALHVVEK 175
Query: 175 REDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIMIYGRQ 232
+DG++V G + T A + E + P+ ++ D Y+++FA+ ++ G+ + R+
Sbjct: 176 NDDGVIVDGIRLLATQAGITDEIFVFPSTVVKSGAKDDPYSLAFAIANNTPGLRYL-SRE 234
Query: 233 SCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVERFAGYH 291
S D K D +G S+F +A+V FD V VP +R+F+ ++ + G E A H
Sbjct: 235 SFDYGK--NNFDHPVG-SQFEEGDAIVAFDNVLVPWDRIFILEDSEICNGAFAETNAVVH 291
Query: 292 RQSYGGCK-VGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEG 350
K + + L+G D G+ H+KDK E++ E + +
Sbjct: 292 MSHQVIAKDIAKVEFLLGVVLKLMDSIGIDGFQHVKDKGTEIMLALENMKSHLYKAEYNA 351
Query: 351 TQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
+ G D N + R+ +A + + ++ +P+ DF + E+GPI+
Sbjct: 352 KIDRWGMMTPDFEALNAARNWFPRVYPRLAEILRVLGASGLMGIPTYDDFANKELGPILN 411
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGT 438
+ + G + E R+++ RL ++T+ +
Sbjct: 412 RAMQGKNVEGFE-RVQLFRLAWDMTMSS 438
>gi|72384120|ref|YP_293474.1| 4-hydroxyphenylacetate 3-hydroxylase [Ralstonia eutropha JMP134]
gi|72123463|gb|AAZ65617.1| 4-hydroxyphenylacetate 3-hydroxylase [Ralstonia eutropha JMP134]
Length = 513
Score = 125 bits (315), Expect = 5e-27, Method: Composition-based stats.
Identities = 115/445 (25%), Positives = 204/445 (45%), Gaps = 31/445 (6%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ T E Y+++LR VY GER+++ HP S+A Y +A E + MT T
Sbjct: 24 LRTGEDYLQNLRDGRC-VYVNGERVKDVTTHPAFSRGAQSLANLYDIAAAPENRERMTFT 82
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVG-MDAFNAIYSTTYEMD 119
S +G V R + ++ EDL+ K + + T R + F Y+ +
Sbjct: 83 SPTSGNPVLRAYQIPKTHEDLRAKRLASEMWSEATFGLMGRSPDHVSNFFVGYAAVPSVF 142
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
A G Y + + +++++N L A+ P+ DR +Q+DP LY +V+ R+DGI
Sbjct: 143 AAGGQEYADNVVSFYEHLRENHLYTTYAIVPPQIDRSKPAHQQSDPTLYAGVVKERDDGI 202
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
++ GA+ T V S + M+ D +YA A+P++A GV +Y R+
Sbjct: 203 IIKGAQQLATAGVYSDYIYVSSIHPMQPGDENYAFGVAIPANAPGV-KLYPRRPFGALAT 261
Query: 240 EEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCK 299
D L +S F + VV D VFVP E VF+ + Q A +++ YG +
Sbjct: 262 NS-FDYPL-SSRFDESDCFVVLDNVFVPWEHVFIYRNLQVAR---DQWWKTPAHLYGNLQ 316
Query: 300 VGVGDV-----LIGAAALAADYNGVPKASHIKDKLIEMIHL----NETLYACGIACSSEG 350
+ ++G A + G ++ ++ E+ L L + +A +++
Sbjct: 317 AQARYITKLRFMMGLAKRMNEMTGNDANPAVQIQMGELASLVSIIEHALISQEVAATTDA 376
Query: 351 TQM----KAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEI 405
+ + G Y I L + + + + EI R +++G M+T+PS +DFR+PE
Sbjct: 377 NGVLWPSRTGLYSIMALQSELNARMV-----EIIR---ELSGAGMITLPSSVEDFRNPET 428
Query: 406 GPIVKKYLAGATGKSTENRMRVLRL 430
V++Y A ++ + E R+ ++R+
Sbjct: 429 AEDVQRYYASSSSDAKE-RVALMRM 452
>gi|7672524|gb|AAF66546.1|AF140605_2 phenol 2-hydroxylase component A [Geobacillus thermoglucosidasius]
Length = 504
Score = 124 bits (310), Expect = 2e-26, Method: Composition-based stats.
Identities = 126/505 (24%), Positives = 237/505 (46%), Gaps = 46/505 (9%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
MM ++Y+ESLR N VY GE+I++ HP + S+A Y ++ ++T T
Sbjct: 4 MMNGKEYLESLRD-NRVVYLNGEKIDDVTTHPAYENAARSIARMYDALHDEQMGKILTTT 62
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+ G + ++F ++ +DL ++ + + Q + G Y ++
Sbjct: 63 TE-EGYRTHKFFKEPKNAQDL---LEARDAIAQWAKLSY----GFMGRTPDYKASF---- 110
Query: 121 ALGTTYHKRFIEYMKYVQDNDL-----------VVDGAMTDPKGDRGLSPSEQADPDLYL 169
T + K F +Y + +DN ++ + +P+ DR S + D+++
Sbjct: 111 ---TAHLKAFADYYEGFEDNARNWYKKTTKEIPFINHTIINPQVDR--SKPLHENKDVFV 165
Query: 170 HIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADAD--YAVSFAVPSDAEGVIM 227
V+ R+DGI+VSGAK T A +H + + A D D +A+ F VP +A GV M
Sbjct: 166 RAVKERDDGIIVSGAKMVGTAAALTHYNFVSNYGAQDLGDGDQSHALIFFVPMNAPGVKM 225
Query: 228 IYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVE 285
I RQS + G+ D +S F ++A++V D VF+P E VF K + G VE
Sbjct: 226 I-SRQSYEQIAKTLGSPFDYPLSSRFDENDAVIVLDNVFIPWENVFAYKNVKVVNGFFVE 284
Query: 286 RFAGY-HRQSYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYAC 342
G+ +R ++ GC + V D ++G A + G + ++ + E++ +A
Sbjct: 285 --TGFVNRFTFQGCTRFAVKLDFMVGLLMKATEAAGTKQFRGVQANIGEVVAFRNMFWAL 342
Query: 343 GIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFR 401
A ++ +M+ G + +L + + + ++ E + G ++ +PS DF
Sbjct: 343 STAMAAN-CEMRNGVALPNLQYGAAYRVLAPMVWPRVKQIFEQVVAGGLIQLPSSANDFL 401
Query: 402 HPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIM 460
+PE+ P + +Y G +G E R++++++I + +GT G + ++ AG+ + R+
Sbjct: 402 NPELRPYLDRYYRG-SGIGAEERVKLMKMIWD-AIGTEFGGRHELYEINYAGNHENIRLE 459
Query: 461 IARQGDLEGKKKLARAIAHIDESLD 485
+ D+ G + R A +D +LD
Sbjct: 460 TLKIADVTGDSE--RFKAFVDSALD 482
>gi|15807887|ref|NP_285546.1| 4-hydroxyphenylacetate-3-hydroxylase [Deinococcus radiodurans R1]
gi|6460705|gb|AAF12410.1|AE001863_35 4-hydroxyphenylacetate-3-hydroxylase [Deinococcus radiodurans R1]
Length = 504
Score = 122 bits (306), Expect = 6e-26, Method: Composition-based stats.
Identities = 117/460 (25%), Positives = 205/460 (44%), Gaps = 38/460 (8%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
+T +++++ LR+ +Y G+R+ +P HP R S+A Y L ++ K +T
Sbjct: 21 VTGQRFLDRLRQNPPTLYIDGQRVADPTTHPSTRNMCQSLAGLYDLQFQEDLKETLTYED 80
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQ------------KTASCFQRCVGMDAFN 109
GK+ R + ++ +DL+ + R+ A+ G + FN
Sbjct: 81 G--GKRYARSFMVPRTKDDLRLIAESHRIRANYGLGFLGRAPDYMNANVMAAGAGAEYFN 138
Query: 110 AIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYL 169
S D + R Y +YVQ NDL + A+T+P+ +R SE DP + L
Sbjct: 139 GC-SAAVPGDPKRDFAANMR--RYYEYVQGNDLCLTHALTNPQVNRSKMASELPDPYIAL 195
Query: 170 HIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMRE-AD-ADYAVSFAVPSDAEGVIM 227
IVE ++G++V GA+ T + + E LI P+ ++E AD + YA+ F +P++ G +
Sbjct: 196 GIVEETDEGVIVRGARMMATLPI-ADEILIFPSTVLKENADKSRYAMGFGIPTNTPG-LS 253
Query: 228 IYGRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERF 287
R+ D + E + +S F +A V+FD V VP ER+F+ + + A
Sbjct: 254 FQCREPIDVGRDPEDHPL---SSRFDEQDAFVIFDDVLVPWERIFLLYDVELANKAYAGT 310
Query: 288 AGYHRQSYG--GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
+Y K+ + +G A + G H++ K+ E+I + E + A +A
Sbjct: 311 DAVLHMAYQVVNLKIAKTEAFLGTAQSIVNAIGSGGFQHVQAKIAEIIIMLEIMKALEVA 370
Query: 346 CSSEGTQ-----MKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDF 400
+ M +D N N RLP L + + ++ MPS+ D
Sbjct: 371 AREQAEPNDYGVMTPARAPLD-AARNYYPANHARLP----ELLQLLGASGIIMMPSKADR 425
Query: 401 RHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAA 440
P +GP + KYL + E R+R+ RL ++++ + A
Sbjct: 426 EGP-LGPQIAKYLQTGNANADE-RLRLFRLAWDMSMSSFA 463
>gi|94971886|ref|YP_593926.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Deinococcus geothermalis DSM 11300]
gi|94553937|gb|ABF43852.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Deinococcus geothermalis DSM 11300]
Length = 495
Score = 120 bits (301), Expect = 2e-25, Method: Composition-based stats.
Identities = 119/466 (25%), Positives = 208/466 (44%), Gaps = 54/466 (11%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
+T +Q+++ LR+ +Y G+R+E+P HP R S+A Y L + +T
Sbjct: 4 ITGQQFLDRLRQNPPTLYIDGQRVEDPTTHPATRNMCRSLAGLYDLQHDPALRDKLTYEE 63
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRC------------VGMDAFN 109
G++ + ++ EDL + R+ + R G + FN
Sbjct: 64 G--GERYAMSLLIPRTKEDLARIGEAHRIRADYSLGFLGRAPDYMNANVMAAGAGAEYFN 121
Query: 110 AIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYL 169
++ ++ +R+ EY V+ +DL + A+T+P+ +R SE DP + L
Sbjct: 122 QCSASVPGSERRDFAANMRRYYEY---VRTHDLCLTHALTNPQVNRAKLASELPDPYIAL 178
Query: 170 HIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMRE-AD-ADYAVSFAVPSDAEGVIM 227
+VE RE+GI+V GA+ T + + E LI P+ ++E AD + YA+ FA+P++ G +
Sbjct: 179 GVVEEREEGILVRGARMMATLPI-ADEILIFPSTVLKENADKSRYAMGFAIPTNTPG-LS 236
Query: 228 IYGRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERF 287
R+ D + E D LG S F +A V+FD V VP ERVF+ + + A
Sbjct: 237 FQCREPFDVGRDPE--DHPLG-SRFDEQDAFVIFDDVLVPWERVFLLYDVELANKAYAAT 293
Query: 288 AGYHRQSYG--GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYA---- 341
+Y K+ + +G A + G H++ K+ E+I + E + A
Sbjct: 294 DAVLHMAYQVVNLKIAKTEAFLGTAQSIVNAIGSGGFQHVQSKVAEIIIMLEIMKALEVA 353
Query: 342 ---------CGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMV 392
G+ + G A NY + RLP L + + ++
Sbjct: 354 AVAGAAVNESGVMTPARGPLDAARNYYPSVY---------ARLP----ELLQLLGASGII 400
Query: 393 TMPSQQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGT 438
MP + D P +GP ++KYL A S E+R+++ RL ++++ +
Sbjct: 401 MMPGKADREGP-LGPQIQKYLQ-AGNASAEDRLKLFRLAWDMSMSS 444
>gi|24575103|gb|AAL06674.1| chlorophenol-4-monooxygenase [Streptomyces globisporus]
Length = 527
Score = 117 bits (294), Expect = 1e-24, Method: Composition-based stats.
Identities = 112/444 (25%), Positives = 195/444 (43%), Gaps = 32/444 (7%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
+T E+Y+ESLR +VY G R+++ HP A Y K ++TA +
Sbjct: 21 LTGEEYLESLRDAR-EVYLDGSRVKDVTAHPAFHNPARMTARLYDSLHDPAQKAVLTAPT 79
Query: 62 NLTGKQVNRFCHLHQSTEDL-KDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+ +RF +S +DL KD+ + AS ++ G + Y ++
Sbjct: 80 DAGDGFTHRFFTAPRSVDDLVKDQAAI--------ASWARKSYGWMGRSPDYKASFLGTL 131
Query: 121 ALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
+++ F + + + Q+ L + A P DR L E D +++H+ +
Sbjct: 132 GANADFYEPFADNARRWYRESQEKVLYWNHAFLHPPVDRSLPADEVGD--VFIHVERETD 189
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDT 236
G+VVSGAK TG+ +H I + D +A+ VP DA+G+ +I R S
Sbjct: 190 AGLVVSGAKVVATGSALTHAAFI-SHWGLPIKDRKFALVATVPMDADGLKVIC-RPSYSA 247
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSY 295
G+ D +S ++A++V D+V +P E VF+ ++ + R ++
Sbjct: 248 NAATTGSPFDNPLSSRLDENDAILVLDQVLIPWENVFVYGNLGKVHLLAGQSGMIERATF 307
Query: 296 GGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
GC ++ V + + G A A D G ++ +L E++ ++ A +
Sbjct: 308 HGCTRLAVKLEFIAGLLAKALDITGAKDFRGVQTRLGEVLAWRNLFWSLSDAAARNPVPW 367
Query: 354 KAGNYMIDLLLANVCKQNITR------LPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGP 407
K G LL N R P + + +D+A GLM S +DFR+PE GP
Sbjct: 368 KNGT-----LLPNPQAGMAYRWFMQIGYPRVLEIVQQDVASGLMYVNSSTEDFRNPETGP 422
Query: 408 IVKKYLAGATGKSTENRMRVLRLI 431
++KYL G+ G R++V++L+
Sbjct: 423 YLEKYLRGSDGAGAVERVKVMKLL 446
>gi|118734039|ref|ZP_01582547.1| 4-hydroxyphenylacetate 3-hydroxylase [Delftia acidovorans SPH-1]
gi|118666044|gb|EAV72646.1| 4-hydroxyphenylacetate 3-hydroxylase [Delftia acidovorans SPH-1]
Length = 504
Score = 116 bits (290), Expect = 4e-24, Method: Composition-based stats.
Identities = 115/467 (24%), Positives = 201/467 (43%), Gaps = 15/467 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T QY +S+R +V+ GER+++ HPM +P ++ A Y L + +T
Sbjct: 4 TGSQYRDSIRD-GRRVWMNGERVKDVTTHPMFKPLVDIRARMYDLQHEAALRDALTCDEG 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD--Q 120
G++ L + +D DK + L+ + R VG ++ ++S D
Sbjct: 63 -DGERHPIAHKLPLTRQDWWDKRRATDLLLEDMGGVVMR-VGDESVGEMWSLFDGQDVLN 120
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + +++ V DL A TDPKGDR P +Q DPD+ LH+V+ + G++
Sbjct: 121 ELDPRFSANIRTHIRRVVRGDLFHVSANTDPKGDRSRLPQDQ-DPDVLLHVVKETDAGVI 179
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAM--READADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
V GAK ++T A +++ P +A A ++YA+ F A G+ I R R
Sbjct: 180 VRGAK-YETAAAYANQAFTKPGLAHWGDAAQSEYAIGFICDLGAPGLRFIC-RPGLAARA 237
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
+ + + F +A+VVFD V VP E V + + A + E Y ++
Sbjct: 238 SAQDHPL---SHRFDEVDAIVVFDDVLVPWENVLFYRHTRAAHFLRETLHRYSAFTFLQR 294
Query: 299 KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNY 358
+ + D+LIG A A GV K ++D+L + E + A A + + AG
Sbjct: 295 SLKLADMLIGTALHNARQTGVEKLQAVQDRLAGLACYREGINAHLTAAIALAERSPAGLM 354
Query: 359 MIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATG 418
M + L + T + + ++ GG + P F + + GP ++K+
Sbjct: 355 MPNQSLLFTGRSLATSQLHHMMNTVRELCGGQVCLTPDHASFENEDTGPWLRKFYTLGPQ 414
Query: 419 KSTENRMRVLRLIENITLGTAAVGYRTE-SMHGAGSPQAQRIMIARQ 464
++R ++L ++ L + G+R + P AQ + R
Sbjct: 415 WQADDRRKLLAYARDL-LDSDHAGHRLSFQLFAQCPPYAQTAAVYRH 460
>gi|116671115|ref|YP_832048.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Arthrobacter sp. FB24]
gi|116611224|gb|ABK03948.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Arthrobacter sp. FB24]
Length = 484
Score = 115 bits (288), Expect = 6e-24, Method: Composition-based stats.
Identities = 108/435 (24%), Positives = 190/435 (43%), Gaps = 14/435 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERI-ENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T QY++ L + V GE + E +HP R S A + + ++ +T TS
Sbjct: 5 TGRQYLDKLNAMTPHVVIDGEVVSEKIAEHPAFRNVARSYAKLFDMQHDPAHQEALTYTS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVG-MDAFNAIYSTTYEMDQ 120
TG VN + ++ EDL+ + + + + R M++ ST +
Sbjct: 65 PTTGDLVNASFLVPRTIEDLQRRRRAISTWAESSHGFLGRSGDYMNSSLTALSTAEKWFS 124
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
+ + Y ++ ++ND++ + P+ +R +S SEQ L IVE R+DGIV
Sbjct: 125 QADPKFGENIRRYYEWARENDVLATHTLIPPQVNRSVSGSEQMGGQLSARIVEERDDGIV 184
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMR--EADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
+SGA+ T A + E L+ P+ +R DA Y+ +FA+P+DA G+ R C
Sbjct: 185 ISGARMLATIAPIADELLVFPSTVLRGTPEDAPYSYAFAIPNDAPGL-----RYLCRASL 239
Query: 239 MEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVERFAG-YHRQSY 295
G+ D S + +A+ +FD VFVP+ER+FM Q E AG
Sbjct: 240 YNGGSTHDEPLASRYEEMDAVAIFDNVFVPSERIFMLGHPQLCNAFYTETGAGALMTHQV 299
Query: 296 GGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKA 355
+ + +G A+ A+ G+ HI++ + E+I E A A ++ +A
Sbjct: 300 VTRTIAKSEFFLGLASELAESIGIDGFQHIQEDIAELIIDVEIGKALVRASEADAGLNEA 359
Query: 356 GNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
G + N + ++ ++ + ++ +P + D + E ++ YL G
Sbjct: 360 GVMLPKWTTLNAARNWYPKIAQRFPQIIRKFSASGLMALPGEADV-NSEARADIEMYLQG 418
Query: 416 ATGKSTENRMRVLRL 430
T E R+R+ +L
Sbjct: 419 KTLTGPE-RVRLFKL 432
>gi|148656690|ref|YP_001276895.1| 4-hydroxyphenylacetate 3-hydroxylase [Roseiflexus sp. RS-1]
gi|148568800|gb|ABQ90945.1| 4-hydroxyphenylacetate 3-hydroxylase [Roseiflexus sp. RS-1]
Length = 521
Score = 114 bits (286), Expect = 1e-23, Method: Composition-based stats.
Identities = 108/441 (24%), Positives = 193/441 (43%), Gaps = 24/441 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
+T E+Y+ESLR +++ GER+++ HP R + VA Y E + ++T T
Sbjct: 13 LTGEEYLESLRD-GREIWIYGERVKDITTHPAFRNATRMVARLYDALHDPEKQAVLTCPT 71
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G ++F +S E+L + T R + A + T +
Sbjct: 72 DTGNGGFTHKFFRASRSAEELVGARDAIAEWARLTYGWMGRS---PDYKAAFLATLGANA 128
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
T Y + + + Q+ L + A+ +P DR SP E D +Y+H+ + G++
Sbjct: 129 EFYTPYQENARRWYRESQERVLYFNHAIVNPPIDRNRSPDEVRD--VYMHVERETDAGLI 186
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ +H + I + ++A+ F VP DA GV +I R S +
Sbjct: 187 VSGAKVVATGSALTHYNFIAHYGPLPIKSKEFALIFIVPMDAPGVKLI-ARPSYEMAAEV 245
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC- 298
G+ D +S +++++VFD+V +P E VF+ + + R ++ GC
Sbjct: 246 MGSPFDYPLSSRLDENDSVMVFDQVLIPWENVFVYGDVEKVNAFFPLSGFIPRFTFHGCT 305
Query: 299 KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
++ V D + G A D G ++ ++ E++ +A A + G
Sbjct: 306 RMAVKLDFIAGLFLKAIDATGAKDFRGVQARVGEVLAWRNLFWAISDAMARTPIPWNEGA 365
Query: 358 YMIDL-------LLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
+ +L + A V I L + D+A L+ DF+ PEI +
Sbjct: 366 VLPNLDYGLAYRVFATVAYPRIKEL------IENDVASALIYLNSHAVDFKTPEIRGYLD 419
Query: 411 KYLAGATGKSTENRMRVLRLI 431
KYL G+ G S+ +R+++++L+
Sbjct: 420 KYLRGSNGYSSLDRVKLMKLL 440
>gi|78063257|ref|YP_373165.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia sp. 383]
gi|77971142|gb|ABB12521.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia sp. 383]
Length = 492
Score = 114 bits (285), Expect = 1e-23, Method: Composition-based stats.
Identities = 121/447 (27%), Positives = 198/447 (44%), Gaps = 46/447 (10%)
Query: 6 QYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTG 65
Q++ SLR +VY G+ + + H R S+ S A Y DE MT S +G
Sbjct: 7 QHIASLRD-GRQVYLNGQPVGDVTAHAAFRNSIRSYASLYDYQARDENVEKMTFVSPDSG 65
Query: 66 KQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQRCV-GMDAFNAIYS 113
+V+R L S ++L ++ MG+ ASC V G D F
Sbjct: 66 NRVSRIWQLPTSYDELVERRAAMEAWSELHYGFMGRSPDHVASCLSGMVMGADVFE---- 121
Query: 114 TTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ D A +Y +Y +DNDL + + +P+ ++ S EQ D L + IV+
Sbjct: 122 ---QYDPARAGALR----DYYRYARDNDLFLTYVIVNPQANQSKSAHEQEDKYLAVGIVD 174
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
+GI V GAK T + ++E +RE D YA+SFAVP +A+G + I R+S
Sbjct: 175 QDAEGITVRGAKMLATSGIMANEVFCSCIQPLREGDEMYALSFAVPMNAKG-MKILSRKS 233
Query: 234 CDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVF------MCKEYQFAGMMV 284
EE A N S F ++A++ FD V VP ER+F MC + QF
Sbjct: 234 -----YEENATSVFDNPLSSRFDENDAVLYFDDVKVPWERIFVAGNTAMCAK-QFHATPA 287
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ Y Q K+ L+G ++ NG +++ L ++ + A
Sbjct: 288 HVYQNYQCQVRLMTKL---RFLVGLGLKISEVNGTNTFPQVRETLGQLAAEASMVEAWVY 344
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHP 403
++GT + G Y+ D + + +L ++ ++AGG M+ +PS +DF +P
Sbjct: 345 GMEAKGTVVN-GFYVPDRNMLYGSQVVTQQLYSKVLNTLRELAGGGMIMLPSSVRDFENP 403
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRL 430
++ I++K S+E R++ +L
Sbjct: 404 DLLRIIEKTQKSPVC-SSEERVKFFKL 429
>gi|154244334|ref|YP_001415292.1| 4-hydroxyphenylacetate 3-hydroxylase [Xanthobacter autotrophicus
Py2]
gi|154158419|gb|ABS65635.1| 4-hydroxyphenylacetate 3-hydroxylase [Xanthobacter autotrophicus
Py2]
Length = 494
Score = 114 bits (285), Expect = 1e-23, Method: Composition-based stats.
Identities = 117/448 (26%), Positives = 206/448 (45%), Gaps = 43/448 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T ++ SLR +++ G++I + HP R ++ SV + + + LMT ++
Sbjct: 4 TGSAHIASLRD-GREIFLDGQKISDATTHPAFRRAVASVGRMFDFHSAPDNRALMTFETD 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVK--------MQRLMGQ---KTASCFQRC-VGMDAFNA 110
TG NR L S ++LK + + +G+ ASC +G+D F
Sbjct: 63 -TGTLANRIWQLPTSYDELKTRRRGLEAWTELHAGFLGRAPDHVASCISGMYMGLDQFE- 120
Query: 111 IYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
+Y +ALG +Y ++ +DNDL + + +P+ DR + +EQADP L
Sbjct: 121 LYDPARA--RALG--------DYYRHARDNDLYLTYVIINPQADRSKNAAEQADPFLSAA 170
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYG 230
IV+ GI V GAK TG + ++E + +++ + YA+SFA+P + +G + I
Sbjct: 171 IVDEDTSGITVRGAKMLATGGIMANEVFVTCIQPLQKGEEAYALSFAIPMNTKG-LKILS 229
Query: 231 RQSCDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERF 287
R+S E GA N S F ++A++ FD V VP +RVF+ + G
Sbjct: 230 RKS-----YEAGAPSVFDNPLSSRFDENDAVLYFDDVKVPWDRVFIAGDIAMTGRQFHAT 284
Query: 288 AGYHRQSY-GGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
+ Q+Y ++ V L+ A A+ NG +++ L ++ + A A
Sbjct: 285 PAHVYQNYQAQIRLSVKLKFLLAIARRTAEVNGTTGFPQVRETLGQLAAEAAMVDAFVAA 344
Query: 346 CSSEGTQMKAGNYMIDLLLANVCKQNITRLPYE--IARLAEDIAGGLMVTMPSQ-QDFRH 402
++G+ G Y + Q +T+ Y I L E +AGG M+ +PS D+++
Sbjct: 345 MEAKGSFY--GPYFVPDRHTLYAAQTLTQQLYGKFITSLRE-LAGGGMIMLPSSVHDYQN 401
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRL 430
PE+ ++ K + S E +++ +L
Sbjct: 402 PELAALIAK-TQQSPAASAEEKVKFYKL 428
>gi|118713948|ref|ZP_01566510.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia
MC0-3]
gi|118648584|gb|EAV55387.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia
MC0-3]
Length = 492
Score = 112 bits (280), Expect = 5e-23, Method: Composition-based stats.
Identities = 119/447 (26%), Positives = 199/447 (44%), Gaps = 46/447 (10%)
Query: 6 QYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTG 65
Q++ SLR +VY G+ + + H R S+ S A Y DE MT S +G
Sbjct: 7 QHIASLRD-GRQVYLNGQPVGDVTAHAAFRNSIRSYASLYDYQARDENVEKMTFVSPGSG 65
Query: 66 KQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQRC-VGMDAFNAIYS 113
+V+R L S ++L ++ MG+ ASC +G D F
Sbjct: 66 NRVSRIWQLPTSYDELVERRAALEAWSELHYGFMGRSPDHVASCLSGMYMGADVFE---- 121
Query: 114 TTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ D A +Y +YV+DNDL + + +P+ ++ + EQ D L + IV+
Sbjct: 122 ---QYDPARAGALR----DYYRYVRDNDLFLTYVIVNPQANQSKAAHEQEDKYLAVGIVD 174
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
+GI V GAK T + ++E +RE D YA++FAVP +A+G + I R+S
Sbjct: 175 QDAEGITVRGAKMLATSGIMANEVFCSCIQPLREGDEMYALTFAVPMNAKG-MKIMSRKS 233
Query: 234 CDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVF------MCKEYQFAGMMV 284
EE A N S F ++A++ FD V VP ER+F MC + QF
Sbjct: 234 -----YEENATSVFDNPLSSRFDENDAVLYFDDVKVPWERIFVAGNTAMCAK-QFHATPA 287
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ Y Q K+ L+G ++ NG +++ L ++ + A
Sbjct: 288 HVYQNYQCQVRLMTKL---RFLVGLGLKISEINGTNTFPQVRETLGQLAAEASMVEAWVY 344
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHP 403
++GT + G Y+ D + + +L ++ ++AGG M+ +PS +DF +P
Sbjct: 345 GMEAKGTVVN-GFYVPDRNMLYGSQVVTQQLYSKVLNTLRELAGGGMIVLPSSVRDFENP 403
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRL 430
++ I++K S+E R++ +L
Sbjct: 404 DLLRIIEKTQKSPVC-SSEERVKFFKL 429
>gi|55978432|ref|YP_145488.1| phenol hydroxylase component A [Thermus thermophilus HB8]
gi|55773605|dbj|BAD72045.1| phenol hydroxylase component A [Thermus thermophilus HB8]
Length = 521
Score = 112 bits (280), Expect = 6e-23, Method: Composition-based stats.
Identities = 134/513 (26%), Positives = 229/513 (44%), Gaps = 60/513 (11%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTY-KLAEMDEYKHLMTAT 60
MT E+Y+ESLR +VYFMGER+++ HP R + A Y +L E+ +K + +
Sbjct: 16 MTGEEYLESLRD-GREVYFMGERVKDVTTHPAFRNTARMFARWYDRLHEL--HKEDLERS 72
Query: 61 SNLTG-------KQVNRFCHLH----QSTEDLKDKVKMQRLMGQKTASCFQRCV----GM 105
+ +G + N + H +S EDL L + T + QR V G
Sbjct: 73 KDPSGWKWTVPTESGNGWTHPFFVGPRSAEDL--------LKARDTIAELQRTVYGWGGR 124
Query: 106 DA-FNAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQAD 164
+ A + T + Y + + K Q+ L + A+ +P DR P E+
Sbjct: 125 SPDYKAAFVGTLGPNAEFYAPYQENARRWYKETQEKLLYWNHAIVNPPVDRH-KPVEEVG 183
Query: 165 PDLYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEG 224
D+Y+H+ + GIVVSGAK TG+ +H + I + D +A+ F VP DA+G
Sbjct: 184 -DVYMHVERETDAGIVVSGAKVVATGSAFTHVNFIAHYGPLPIKDKKFALIFVVPMDAKG 242
Query: 225 VIMIYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMM 283
V +I R S + + G+ D +S ++A++VFD V VP E VF+ + +
Sbjct: 243 VKLI-SRASYEFIAAKTGSPFDYPLSSRLDENDAILVFDNVLVPWENVFVYGDVEKVNAF 301
Query: 284 VERFAGYHRQSYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYA 341
HR + GC ++ V D + G A D G + ++ +L E++ +A
Sbjct: 302 FPLSGFVHRFPFQGCTRLAVKLDFIAGLTMKALDVTGASQFRGVQARLGEILTYRNLFWA 361
Query: 342 CGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPY-EIARLAEDIAGGLMVTMPSQ-QD 399
A + + G Y++ L A + + + Y +I + E ++ +PS +D
Sbjct: 362 LTEAMARDPMPWVDG-YVLPNLWAGLTYRVLAPEVYPKIKDIIERDLASALIYLPSHAKD 420
Query: 400 FRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG---------------YR 444
F++P+I + +Y+ G G R+++++ + + +GT G R
Sbjct: 421 FQNPQIRRYLDQYVRG-NGVDAVTRVKIMKALWD-AVGTEFGGRHELYERNYAGNHENIR 478
Query: 445 TE---SMHGAGSPQAQRIMIAR---QGDLEGKK 471
E +M AG +A R + + + DLEG K
Sbjct: 479 IEVLGAMEAAGVNEALRAFVDKFLGEYDLEGWK 511
>gi|94496803|ref|ZP_01303378.1| 4-hydroxyphenylacetate 3-hydroxylase [Sphingomonas sp. SKA58]
gi|94423816|gb|EAT08842.1| 4-hydroxyphenylacetate 3-hydroxylase [Sphingomonas sp. SKA58]
Length = 488
Score = 112 bits (279), Expect = 6e-23, Method: Composition-based stats.
Identities = 123/452 (27%), Positives = 196/452 (43%), Gaps = 48/452 (10%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T Q++ +LR +Y G+ + HP S+ S A Y + LMT T
Sbjct: 1 MKTGSQHLATLRD-GRSIYIDGKLAGDVTQHPAFCNSVASAARLYDFQAAN--PDLMTFT 57
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQ-RCVGMDAF 108
S +G++VNR L E L + K MG+ ASCF +G+D F
Sbjct: 58 SPSSGERVNRAWDLPTDYEGLVMRRKAMEAWAGTHYGFMGRSPDHVASCFAGMMMGIDLF 117
Query: 109 NAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLY 168
D+A +Y +Y +DNDL + + +P+ DR S EQADP L
Sbjct: 118 E-------NHDRARAGA----LADYFRYARDNDLFLTYVIINPQADRSKSAHEQADPYLT 166
Query: 169 LHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMI 228
IV+ GI + GAK T + ++E + + D YA+S AVP +A GV ++
Sbjct: 167 AGIVDEDSTGITIRGAKMLATSGIMANEVFVSCVQPLGVGDEKYAISLAVPMNAPGVKLL 226
Query: 229 YGRQSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMM 283
+RK E A D L S F ++A++ FD V VP +RVF+ +
Sbjct: 227 -------SRKSYEAASPSQFDNPLA-SRFDENDAVIYFDDVKVPWDRVFIAGDTAMVMKQ 278
Query: 284 VERFAGYHRQSYGGCKVGV---GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLY 340
+ Q+Y C+V + L+G A A+ NG ++D L ++ E
Sbjct: 279 FHATPAHVLQNY-QCQVRLMVKMRFLMGIARRTAEINGTLALPPVRDMLGQLA--AEAAL 335
Query: 341 ACGIACSSEGT-QMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-Q 398
G+ E +++ G Y+ D L + +L ++ D+AGG ++ +PS
Sbjct: 336 VEGMVHGMEAKGKVRNGYYIPDGHLLYASQVLTQQLYSKVITSLRDLAGGGLIMLPSSIA 395
Query: 399 DFRHPEIGPIVKKYLAGATGKSTENRMRVLRL 430
DF +PE ++ K S ++R++ +L
Sbjct: 396 DFVNPETAALIGKTQQSPVANS-QDRVKFFKL 426
>gi|156742383|ref|YP_001432512.1| 4-hydroxyphenylacetate 3-hydroxylase [Roseiflexus castenholzii DSM
13941]
gi|156233711|gb|ABU58494.1| 4-hydroxyphenylacetate 3-hydroxylase [Roseiflexus castenholzii DSM
13941]
Length = 521
Score = 112 bits (279), Expect = 7e-23, Method: Composition-based stats.
Identities = 105/441 (23%), Positives = 194/441 (43%), Gaps = 24/441 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
+T E+Y+ESLR +++ GER+++ HP R + VA Y E + ++T T
Sbjct: 13 LTGEEYLESLRD-GREIWIYGERVKDITTHPAFRNATRMVARLYDALHDAEKQSVLTCPT 71
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G ++F +S +DL + T R + A + T +
Sbjct: 72 DTGNGGFTHKFFRASRSADDLVGARDAIAEWARLTYGWMGRS---PDYKAAFLATLGANA 128
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A + Y + + + Q+ L + A+ +P DR P E D +Y+H+ + G++
Sbjct: 129 AFYSPYQENARRWYRESQERVLYFNHAIVNPPIDRNRPPDEIRD--VYMHVERETDAGLI 186
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ +H + I + ++A+ F VP DA GV +I R S +
Sbjct: 187 VSGAKVVATGSALTHYNFIAHYGPLPIRSKEFALIFIVPMDAPGVKLI-ARPSYEMAAEV 245
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC- 298
G+ D +S ++++++FD+V +P E VF+ + + R ++ GC
Sbjct: 246 MGSPFDYPLSSRLDENDSVMIFDQVLIPWENVFVYGDVEKVNAFFPLSGFIPRFTFHGCT 305
Query: 299 KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
++ V D + G A + G + ++ ++ E++ +A A + G
Sbjct: 306 RMAVKLDFIAGLFLKAVEATGAKEFRGVQARVGEVLAWRNLFWAISDAMARTPIPWNDGA 365
Query: 358 YMIDL-------LLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
+ +L + A V I L + D+A L+ DF+ PEI +
Sbjct: 366 VLPNLDYGLAYRVFATVAYPRIKEL------IESDVASALIYLNSHAVDFKTPEIRGYLD 419
Query: 411 KYLAGATGKSTENRMRVLRLI 431
KYL G+ G S+ +R+++++L+
Sbjct: 420 KYLRGSNGYSSLDRVKLMKLL 440
>gi|15603388|ref|NP_246462.1| hypothetical protein PM1523 [Pasteurella multocida subsp. multocida
str. Pm70]
gi|12721911|gb|AAK03607.1| unknown [Pasteurella multocida subsp. multocida str. Pm70]
Length = 532
Score = 111 bits (278), Expect = 1e-22, Method: Composition-based stats.
Identities = 128/499 (25%), Positives = 219/499 (43%), Gaps = 37/499 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y+ SLR KVY GE +++ HP R + SVA Y L + L T
Sbjct: 24 TGEEYLASLRD-GRKVYIYGELVDDVTTHPAFRNAAASVAKLYDALHDPATKDELCWETD 82
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F ++ E+LK QR A+ + G Y +
Sbjct: 83 TGNGGYTHKFFRYARTAEELK----AQR---DAIAAWSRFSYGWMGRTPDYKAAFGSALG 135
Query: 122 LGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
++ +F + + K +Q++ L + A+ +P DR P +Q D+Y+ I E R D
Sbjct: 136 ANPEFYGKFADNARNWYKRIQESCLYFNHAIVNPPIDRN-KPIDQVK-DIYVKIEEERAD 193
Query: 178 GIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA-DYAVSFAVPSDAEGVIMIYGRQSCDT 236
GIVVSGAK T + +H + I A D D+A+ F P DAEGV +I R S +
Sbjct: 194 GIVVSGAKVVATNSALTHYNFIGFGSAQIIGDNDDFALMFIAPMDAEGVKLIC-RHSYEL 252
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEY-QFAGMMVERFA 288
G+ D ++ F ++A++V D VF+P E + + C+ + Q+AG FA
Sbjct: 253 AAGATGSPFDFPLSTRFDENDAILVLDSVFIPWENILIYRDLERCRTWAQYAG-----FA 307
Query: 289 G-YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
+ Q+ V + D + G A GV + + ++ E++ + A +
Sbjct: 308 TLFPMQACTRLAVKL-DFITGLLHKALQCTGVIEFRGVAAQMGEVMMYRNLFWTLTDAMA 366
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIG 406
Q K G M + + + ++ E ++ +PS +DF +PEI
Sbjct: 367 GSSYQWKNGCQMPSAQAIQTYRVMAPMAYHTVKKIIEQTVTSGLIYLPSHIRDFNNPEID 426
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQG 465
++KY+ G+ +R+++L+L+ + +GT G + ++ AGS + R+ + G
Sbjct: 427 QYLEKYVRGSNNIEYRDRIKILKLLWD-AIGTEFGGRHELYEINYAGSQEEVRLQVL--G 483
Query: 466 DLEGKKKLARAIAHIDESL 484
G L R +D+ L
Sbjct: 484 QSTGNGTLQRCFDLVDKCL 502
>gi|126727835|ref|ZP_01743664.1| 4-hydroxyphenylacetate-3-hydroxylase family protein
[Rhodobacterales bacterium HTCC2150]
gi|126702857|gb|EBA01961.1| 4-hydroxyphenylacetate-3-hydroxylase family protein
[Rhodobacterales bacterium HTCC2150]
Length = 485
Score = 111 bits (278), Expect = 1e-22, Method: Composition-based stats.
Identities = 117/494 (23%), Positives = 213/494 (43%), Gaps = 30/494 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T E+Y S++ +V+ GE++++P HP ++P ++ A Y + + + +MT N
Sbjct: 4 TGEEYRNSIKD-GREVWINGEQVKDPTVHPQLKPIIDVRARIYDMQHDPKTQAVMTYEEN 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD--Q 120
G++ L +D +DK + ++ R VG + ++S D
Sbjct: 63 --GERHAIGMRLPHEAKDWQDKREAVDMVMHDVGGVVTR-VGDETIGEMWSLRDGKDILN 119
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
+ + + +++ D A TDPKGDR +P +Q DPD+ +H+V+ + GI+
Sbjct: 120 EIDPRFAQNIERHIQTCTKEDPFHVSANTDPKGDRSKAPQDQ-DPDMLVHVVKETDAGII 178
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAM--READADYAVSFAVPSDAEGVIMI-----YGRQS 233
+ GAK ++T A S++ + PTIA +DYA+ V +A GV I GR
Sbjct: 179 IRGAK-YETAAAYSNQAFLKPTIANWGNSEMSDYALGCIVKMNAPGVKHICRTGFAGRAP 237
Query: 234 CDTRKMEEGAD-IDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHR 292
D + D ID L++ D V VP E V + + A + Y
Sbjct: 238 ADDYPLSNRVDEID----------TLMILDNVLVPWEDVLFYQHTRAASFIRATLHRYSA 287
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
+ + D++IGAA G+ K +++KL E+ E + A A + +
Sbjct: 288 LPFVQRTLSFADLIIGAALWNVKQTGLDKQQAVQEKLAELAVWREGIEAFLTASIATAEK 347
Query: 353 MKAGNYMIDL-LLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKK 411
+G M + +L + ++ LP ++ +A ++ GG + P F P + K
Sbjct: 348 SPSGLLMPNQSMLMSGRVHALSNLP-KMMHMARELCGGQICVTPDAATFAAAGTKPWMDK 406
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYR-TESMHGAGSPQAQRIMIARQGDLEGK 470
+ ++R ++L L ++ L + G+R T + P AQ + R D G
Sbjct: 407 FYTINEQWVADDRRKLLSLARDL-LNSDYAGHRLTFQLFAQSPPFAQLAAVYRNFDWGGP 465
Query: 471 KKLARAIAHIDESL 484
A A + +++
Sbjct: 466 LDFAHKAAGLSDNV 479
>gi|84353900|ref|ZP_00978820.1| COG2368: Aromatic ring hydroxylase [Burkholderia cenocepacia PC184]
gi|107027005|ref|YP_624516.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia AU
1054]
gi|116691798|ref|YP_837331.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia
HI2424]
gi|105896379|gb|ABF79543.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia AU
1054]
gi|116649798|gb|ABK10438.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia
HI2424]
Length = 492
Score = 111 bits (277), Expect = 1e-22, Method: Composition-based stats.
Identities = 119/447 (26%), Positives = 198/447 (44%), Gaps = 46/447 (10%)
Query: 6 QYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTG 65
Q++ SLR +VY G+ + + H R S+ S A Y DE MT S +G
Sbjct: 7 QHIASLRD-GRQVYLNGQPVGDVTAHAAFRNSIRSYASLYDYQARDENVEKMTFVSPDSG 65
Query: 66 KQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQRC-VGMDAFNAIYS 113
+V+R L S ++L ++ MG+ ASC +G D F
Sbjct: 66 NRVSRIWQLPTSYDELVERRAALEAWSELHYGFMGRSPDHVASCLSGMYMGADVFE---- 121
Query: 114 TTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ D A +Y +Y +DNDL + + +P+ ++ + EQ D L + IV+
Sbjct: 122 ---QYDPARAGALR----DYYRYARDNDLFLTYVIVNPQANQSKAAHEQEDKYLAVGIVD 174
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
+GI V GAK T + ++E +RE D YA+SFAVP +A+G + I R+S
Sbjct: 175 QDAEGITVRGAKMLATSGIMANEVFCSCIQPLREGDEMYALSFAVPMNAKG-MKIMSRKS 233
Query: 234 CDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVF------MCKEYQFAGMMV 284
EE A N S F ++A++ FD V VP ER+F MC + QF
Sbjct: 234 -----YEESATSVFDNPLSSRFDENDAVLYFDDVKVPWERIFVAGNTAMCAK-QFHATPA 287
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ Y Q K+ L+G ++ NG +++ L ++ + A
Sbjct: 288 HVYQNYQCQVRLMTKL---RFLVGLGLKISEVNGTNTFPQVRETLGQLAAEASMVEAWVY 344
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHP 403
++GT + G Y+ D + + +L ++ ++AGG M+ +PS +DF +P
Sbjct: 345 GMEAKGTVVN-GFYVPDRNMLYGSQVVTQQLYSKVLNTLRELAGGGMIMLPSSVRDFENP 403
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRL 430
++ I++K S+E R++ +L
Sbjct: 404 DLLRIIEKTQKSPVC-SSEERVKFFKL 429
>gi|118046179|ref|ZP_01514832.1| 4-hydroxyphenylacetate 3-hydroxylase [Chloroflexus aggregans DSM
9485]
gi|117997344|gb|EAV11532.1| 4-hydroxyphenylacetate 3-hydroxylase [Chloroflexus aggregans DSM
9485]
Length = 530
Score = 111 bits (277), Expect = 1e-22, Method: Composition-based stats.
Identities = 108/446 (24%), Positives = 202/446 (45%), Gaps = 25/446 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTY-KLAEM---------- 50
M +Y+ESLR + VYF GER+++ HP R S VA Y +L E+
Sbjct: 18 MNGREYLESLRD-DRVVYFQGERVKDVTTHPAFRNSARMVARWYDRLHELHQEDVARGDP 76
Query: 51 DEYKHLMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNA 110
D++K M T +G + F ++ EDL V+ + + + + + + A
Sbjct: 77 DQWKWTM-PTDTGSGGWTHPFFVGSRTVEDL---VRARDTIAELQRAVYGWMGRAPDYKA 132
Query: 111 IYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
++ T + Y + + + Q+ + + A+ +P DR P E AD +Y+H
Sbjct: 133 AFTGTLGANAEFYAPYQENARRWYRKTQEELIYWNHAIVNPPIDRNRPPDEVAD--VYMH 190
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYG 230
+ + G++VSGAK TG+ +H + I + + +A+ FAVP +A GV +I
Sbjct: 191 VERETDAGLIVSGAKVVATGSALTHVNFIAHYGPLPIKEKRFALIFAVPMNAPGVKLI-A 249
Query: 231 RQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAG 289
R S + G+ D +S +++++VFDRV +P E +F+ + +
Sbjct: 250 RTSYEYNAAVVGSPFDYPLSSRLDENDSILVFDRVLIPWENIFVYGDIEKVNTFFPISGF 309
Query: 290 YHR-QSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
HR +GG + V D + G A + GV + ++ +L E++ + A
Sbjct: 310 GHRFPLHGGTRFAVKLDFITGLMLKAVESTGVAEFRGVQARLGEIVTYRNLFWHLTEAMV 369
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPY-EIARLAEDIAGGLMVTMPSQ-QDFRHPEI 405
G Y++ L A + + Y +I L E ++ +PS D ++PE+
Sbjct: 370 RNPMPWVDG-YLLPNLEAAFAYRVLAPDAYVKIKDLIEKDVASALIYLPSHAADLKNPEV 428
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLI 431
+ +++ G+ G S +R+++++L+
Sbjct: 429 RAYLDRFVRGSNGTSAFDRIKLMKLL 454
>gi|124875455|gb|EAY65445.1| 4-hydroxyphenylacetate 3-hydroxylase [Burkholderia cenocepacia
PC184]
Length = 505
Score = 111 bits (277), Expect = 1e-22, Method: Composition-based stats.
Identities = 119/447 (26%), Positives = 198/447 (44%), Gaps = 46/447 (10%)
Query: 6 QYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTG 65
Q++ SLR +VY G+ + + H R S+ S A Y DE MT S +G
Sbjct: 20 QHIASLRD-GRQVYLNGQPVGDVTAHAAFRNSIRSYASLYDYQARDENVEKMTFVSPDSG 78
Query: 66 KQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQRC-VGMDAFNAIYS 113
+V+R L S ++L ++ MG+ ASC +G D F
Sbjct: 79 NRVSRIWQLPTSYDELVERRAALEAWSELHYGFMGRSPDHVASCLSGMYMGADVFE---- 134
Query: 114 TTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ D A +Y +Y +DNDL + + +P+ ++ + EQ D L + IV+
Sbjct: 135 ---QYDPARAGALR----DYYRYARDNDLFLTYVIVNPQANQSKAAHEQEDKYLAVGIVD 187
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
+GI V GAK T + ++E +RE D YA+SFAVP +A+G + I R+S
Sbjct: 188 QDAEGITVRGAKMLATSGIMANEVFCSCIQPLREGDEMYALSFAVPMNAKG-MKIMSRKS 246
Query: 234 CDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVF------MCKEYQFAGMMV 284
EE A N S F ++A++ FD V VP ER+F MC + QF
Sbjct: 247 -----YEESATSVFDNPLSSRFDENDAVLYFDDVKVPWERIFVAGNTAMCAK-QFHATPA 300
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ Y Q K+ L+G ++ NG +++ L ++ + A
Sbjct: 301 HVYQNYQCQVRLMTKL---RFLVGLGLKISEVNGTNTFPQVRETLGQLAAEASMVEAWVY 357
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHP 403
++GT + G Y+ D + + +L ++ ++AGG M+ +PS +DF +P
Sbjct: 358 GMEAKGTVVN-GFYVPDRNMLYGSQVVTQQLYSKVLNTLRELAGGGMIMLPSSVRDFENP 416
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRL 430
++ I++K S+E R++ +L
Sbjct: 417 DLLRIIEKTQKSPVC-SSEERVKFFKL 442
>gi|86741459|ref|YP_481859.1| 4-hydroxyphenylacetate 3-hydroxylase [Frankia sp. CcI3]
gi|86568321|gb|ABD12130.1| 4-hydroxyphenylacetate 3-hydroxylase [Frankia sp. CcI3]
Length = 473
Score = 110 bits (274), Expect = 2e-22, Method: Composition-based stats.
Identities = 127/485 (26%), Positives = 213/485 (43%), Gaps = 46/485 (9%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
MT E+Y SL +V+ GE++ N HP R +++ +A + L + + ++T
Sbjct: 1 MTGERYRASLND-GREVWLDGEKVANVATHPAFRGAVDELARLFDLQHDPDLRDVLTVHE 59
Query: 62 NLTGKQVNRFCHLHQSTEDLKDK-----VKMQRLMGQKTAS-CFQRCVGMDAFNAIYSTT 115
G +V L ++ +DL+ + V M+ GQ S F V + + +
Sbjct: 60 PEAGTRVGWSYQLPRTLDDLRARRRSTGVWMRESWGQHGRSPSFMANVAVGLLD--FREH 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E +QA + + + ++ NDLV+ A+ DP+ DR SP + DPDL L I+ R
Sbjct: 118 LECNQA---GFGANAVAFYRHCAANDLVLGHALGDPQIDRTTSPVD--DPDLALRIIAER 172
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIM--PTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
+DG+VV GAK T A +HE L+ + A REA+ + + F +P GV I R+
Sbjct: 173 DDGVVVRGAKQLTTLAPLAHEVLVYLSASFAQREAE-QFVIWFGLPLATPGV-KILCREP 230
Query: 234 CDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
R + S F +A++ FD V VP +RVF+ ++ A + + R +
Sbjct: 231 LGARPYGHAHAL---ASRFDEQDAMLFFDDVLVPWDRVFLLRDGNLARVGLGRINAW--- 284
Query: 294 SYGGCKVGVGD---VLIGAAALAADYNGVPKASHIKDKLIEM---IHLNETLYACGIAC- 346
S + + L+ L AD G H+++ L E+ + L G A
Sbjct: 285 SAAAGHIRYQERLRTLLAVGTLLADAIGASGLRHVQEDLGELASYVDLVGYFLDAGEARA 344
Query: 347 -SSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEI 405
+++G + GN + V + EI R I ++ PS++D ++
Sbjct: 345 ETTDGGLLAPGNTDA----SRVWSAQVAGRAVEIVR---RIGSSGVLMQPSERDLAAADL 397
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRT---ESMHGAGSPQAQRIMIA 462
P + +Y+ GA E + R+ RL +T + G R E +H G RI +
Sbjct: 398 RPYLDRYMRGAN-LPVEEKSRLFRLAWELT--ADSFGQRQDLYEFVH-RGDITRNRINLL 453
Query: 463 RQGDL 467
R+ DL
Sbjct: 454 RRDDL 458
>gi|118072117|ref|ZP_01540308.1| 4-hydroxyphenylacetate 3-hydroxylase [Shewanella woodyi ATCC 51908]
gi|118023324|gb|EAV37137.1| 4-hydroxyphenylacetate 3-hydroxylase [Shewanella woodyi ATCC 51908]
Length = 504
Score = 108 bits (271), Expect = 7e-22, Method: Composition-based stats.
Identities = 110/443 (24%), Positives = 189/443 (42%), Gaps = 39/443 (8%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T +Y+ESL+ +V++ GE I+ HP + + ++A Y ++ M +
Sbjct: 33 TGARYIESLKD-GRQVWYDGEVID-VTRHPSFQGLLMALAELYDKQRLENNSADMLTELD 90
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
QV+ + + E+L K + Q + R D + Y+ L
Sbjct: 91 DGSLQVSASYIVPSTREELDKKWRNSHKWMQLSYGQLPRVP--DFMANVVVGLYDFRHEL 148
Query: 123 GTT---YHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
G + K +Y Y +++D+ + A+ DP+ DR SP E +PD L +V+ ++GI
Sbjct: 149 GKVDPQFEKNAEDYYHYCREHDICLTHALGDPQIDRSASPVE--NPDHALRVVKRTKEGI 206
Query: 180 VVSGAKAHQTGAVNSHEHLIM--PTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTR 237
VV GAK T A HE LI P MRE+ ++ F+VP +A G+ + T
Sbjct: 207 VVHGAKQLATLAPYCHEALIYLSPAFYMRES-PEFVAWFSVPMNAPGLKFLCRESHVGTS 265
Query: 238 KMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAG----------MMVERF 287
A + + ++++ FD VF+P RVF+ + + A + V +
Sbjct: 266 NGFRHA----FSQSYDEQDSMLFFDHVFIPMNRVFLLENTEVAAKGFHELNKWSLYVGQI 321
Query: 288 AGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
YHR +G +L A GV I +++ E+ E + +C +
Sbjct: 322 RFYHRLR----------TFLGVTSLVAKSIGVDGFREIMNRVGELTSYVELVRSCLVGID 371
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGP 407
SE AGN LA +++ I + DI G ++ PS +D +PE+ P
Sbjct: 372 SETRISSAGNIAPGSTLA--LDSFASQIAPRINEILRDIGGSGIIMQPSAKDLANPELRP 429
Query: 408 IVKKYLAGATGKSTENRMRVLRL 430
++KY+ G G + + + RL
Sbjct: 430 YLEKYMKG-KGVDVDFKTDLFRL 451
>gi|116694447|ref|YP_728658.1| 4-Hydroxyphenylacetate-3-hydroxylase [Ralstonia eutropha H16]
gi|113528946|emb|CAJ95293.1| 4-Hydroxyphenylacetate-3-hydroxylase [Ralstonia eutropha H16]
Length = 494
Score = 108 bits (270), Expect = 8e-22, Method: Composition-based stats.
Identities = 114/447 (25%), Positives = 193/447 (43%), Gaps = 39/447 (8%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T Q++ LR +VY G+R+ + HP R S+ S A Y MT
Sbjct: 4 TGNQHIAMLRD-GREVYLDGKRVTDVTSHPAFRNSIRSYANLYDFQAQPGNIDKMTFQPA 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQR--------LMGQK---TASCFQRC-VGMDAFNA 110
T ++V+R L S +L ++ +M MG+ ASC +G+D F
Sbjct: 63 GTDRRVSRIWELPASYNELVERRQMLEAWTELHYGFMGRSPDHVASCISGMYMGIDVFE- 121
Query: 111 IYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
+ D A +Y +Y +DNDL + + +P+ ++ S EQ D L +
Sbjct: 122 ------QADPARAGALR----DYYRYARDNDLFLTYVIVNPQANQSKSAHEQEDKYLAVG 171
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYG 230
IV+ +GI V GAK T + ++E +RE D YA+SFAVP + +G + +
Sbjct: 172 IVDQDAEGITVRGAKMLATSGIMANEVFCSCIQPLREGDEMYALSFAVPMNTKG-LKVMS 230
Query: 231 RQSCDTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERF 287
R+S E A N S F ++A++ FD V VP ER+F+ +
Sbjct: 231 RKS-----YEANATSVFDNPLASRFDENDAVLYFDDVKVPWERIFVAGDVGLCARQFHAT 285
Query: 288 AGYHRQSYGGCKVGVG---DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ Q+Y C+V + L+G A + NG +++ L ++ + A
Sbjct: 286 PAHVYQNY-QCQVRLMVKLRFLVGLAHRITEINGTNSFPQVREMLGQLAAEAGMVEAWVY 344
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHP 403
++G K G ++ D + + +L ++ ++AGG M+ +PS +DF +P
Sbjct: 345 GMEAKGQVGKHGYFVPDRSMLYGSQVVTQQLYGKVLATLRELAGGGMIMLPSSIEDFANP 404
Query: 404 EIGPIVKKYLAGATGKSTENRMRVLRL 430
+ I+ K S E R++ +L
Sbjct: 405 SLAGIIAKTQKSPVC-SPEERVKFFKL 430
>gi|110634806|ref|YP_675014.1| 4-hydroxyphenylacetate 3-hydroxylase [Mesorhizobium sp. BNC1]
gi|110285790|gb|ABG63849.1| 4-hydroxyphenylacetate 3-hydroxylase [Mesorhizobium sp. BNC1]
Length = 520
Score = 108 bits (270), Expect = 8e-22, Method: Composition-based stats.
Identities = 123/500 (24%), Positives = 223/500 (44%), Gaps = 35/500 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-TS 61
T +Y+ESLR +VY GERI + DHP +R + S+A Y + K ++T+ T
Sbjct: 15 TGAEYLESLRD-GREVYINGERIADVTDHPSMRNAARSIARLYDALHDGKTKDILTSPTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G +R+ + +S+ +L V Q + + + + A T +
Sbjct: 74 TGSGGYTHRYFRVARSSNEL---VAQQGAIAEWARMSYGWMGRTADYKAALMNTLGANAD 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + + K Q+ L ++ A+ +P DR P++ A D+++HI + + GI V
Sbjct: 131 WYGPFKENALSWHKRAQEAVLFMNHAIVNPPVDRH-KPAD-AVKDVFVHITKETDAGIYV 188
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEE 241
SGAK T + +H + + A D +V F VP +A G+ M + R S +
Sbjct: 189 SGAKVVATSSALTHYNFLAQGSATVTEDPSLSVMFIVPMNAPGIKM-FCRVSYEQTANSV 247
Query: 242 GADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKE-------YQFAGMMVERFAGYHRQ 293
G D +S F ++A++V D VFVP E V + ++ + +G M H
Sbjct: 248 GHPFDYPLSSRFDENDAILVLDNVFVPWEDVLVLRDAAKILSFHPASGFM-------HGY 300
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
+ GC ++ V D L G A A G + L E+ + ++ A +
Sbjct: 301 CFQGCTRLAVKLDFLAGLLAKALRATGGDAFRGNQAMLGEVFAIRHQFWSFSNAMAYNPI 360
Query: 352 QMKAGNYMIDLLLANVCKQNITR--LPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIV 409
G + +L A +C + P I + +A GL+ S +DF +PEI +
Sbjct: 361 PWSNGAVLPNLEAA-LCYRTFMSEAYPKVIDIIRRTVASGLIYLPSSAKDFANPEIDRYL 419
Query: 410 KKYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQGDLE 468
+Y+ G+ R+++++L+ + T GT G + ++ AG+P+ R+ + + +
Sbjct: 420 SQYVRGSNDMGHIERIKIMKLLWDAT-GTEFGGRHALYELNYAGAPEEVRLQVLKVAERG 478
Query: 469 GKKK-----LARAIAHIDES 483
G+ K + R +A DE+
Sbjct: 479 GRLKEMEALVDRCMADYDEN 498
>gi|3046914|gb|AAC38324.1| phenol hydroxylase [Geobacillus thermoleovorans]
Length = 524
Score = 107 bits (267), Expect = 2e-21, Method: Composition-based stats.
Identities = 112/453 (24%), Positives = 200/453 (44%), Gaps = 41/453 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTY----KLAEMDEYK---- 54
T E+Y+ESLR +VY GER+++ HP R + A Y +L DE +
Sbjct: 13 TGEEYLESLRD-GREVYVYGERVKDITTHPAYRNAARMFARWYDRLHQLHAEDEQRGGPE 71
Query: 55 --HLMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV----GMDA- 107
T G + + + EDL + G+ T + QR V G
Sbjct: 72 NWKWTVPTDTGNGGWTHPYFIGARCAEDL--------IKGRDTIAELQRVVYGWLGRSPD 123
Query: 108 FNAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDL 167
+ A + T + Y + + Q+ L + A+ +P DR P E+ D+
Sbjct: 124 YKAAFVGTLGANSNFYAPYQENAKRWYNETQERLLFWNHAIVNPPVDRN-KPIEEVG-DV 181
Query: 168 YLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIM 227
++H+ + + G+VVSGAK TG+ +H + I + D +A+ F VP +A GV +
Sbjct: 182 FMHVEKETDAGVVVSGAKVVATGSALTHMNFIGQYGPVPVKDKKFALIFTVPMNAPGVKL 241
Query: 228 IYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
I R S + G+ D +S ++A++VFD+V VP E +F+ ++ + R
Sbjct: 242 I-SRASYEFVAAATGSPFDYPLSSRLDENDAILVFDKVLVPWENIFVYEDVEKVNTFFPR 300
Query: 287 FAGYHRQS-YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+R + +G ++ V D + G A + GV ++ ++ E++ ++
Sbjct: 301 SGFINRFTLHGLTRLAVKLDFIAGLVLKATEATGVKDFRGVQARVGEILAWRHLFWSL-- 358
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRL------PYEIARLAEDIAGGLMVTMPSQQ 398
SE ++ D +L N+ R+ P + +D+A L+ +
Sbjct: 359 ---SEAQVRNPEPWVDDYVLPNLSAGLAYRVFASEAYPKIKDLIEKDLASSLIYLPSNAA 415
Query: 399 DFRHPEIGPIVKKYLAGATGKSTENRMRVLRLI 431
DF PEI P ++KY+ G+ G E+R+++L+L+
Sbjct: 416 DFLEPEIRPYLEKYVRGSNGYDAESRVKLLKLL 448
>gi|111020858|ref|YP_703830.1| aromatic ring hydroxylase [Rhodococcus sp. RHA1]
gi|110820388|gb|ABG95672.1| aromatic ring hydroxylase [Rhodococcus sp. RHA1]
Length = 520
Score = 107 bits (267), Expect = 2e-21, Method: Composition-based stats.
Identities = 107/441 (24%), Positives = 198/441 (44%), Gaps = 26/441 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
MT ++Y+ESLR +VYF GER+++ HP R S SVA Y E K ++ T
Sbjct: 20 MTGDEYLESLRD-GREVYFRGERVDDVTTHPAFRNSARSVARMYDALHQPEAKGVLAVPT 78
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
G + F +S +DL ++ + +QR V + A + T
Sbjct: 79 DTGNGGFTHPFFKTARSADDL--------VLSRDAIVAWQREVYGWLGRSPDYKASFLGT 130
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
+ Y + + K+ Q+ L ++ A+ +P DR E A D+ +H+VE
Sbjct: 131 LGANADFYGPYRDNALRWYKHAQERMLYLNHAIVNPPIDRDKPADETA--DVCVHVVEET 188
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMP-TIAMREADADYAVSFAVPSDAEGVIMIYGRQSC 234
+ G++VSGAK TG+ ++ + I + +R+ +Y + F VP D+ G + ++ R S
Sbjct: 189 DAGLIVSGAKVVATGSAITNANFIAHYGLPLRK--KEYGLIFTVPMDSPG-LKLFCRTSY 245
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
+ G D +S F ++A++VFDRV VP E VF + A V + R
Sbjct: 246 EMNAAVMGTPFDYPLSSRFDENDAIMVFDRVLVPWENVF-AYDTDTANGFVMKSGFLSRF 304
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
+ GC ++ V D + G + G ++ ++ E+++ + + A +
Sbjct: 305 MFHGCARLAVKLDFIAGCVMKGVEMTGSAGFRGVQMQIGEILNWRDMFWGLSDAMAKSPE 364
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAG-GLMVTMPSQQDFRHPEIGPIVK 410
Q G +L + + + + + + G GL+ D+ +P + P +
Sbjct: 365 QWVNGAVQPNLNYGLAYRTFMGVGYPRVKEIIQQVLGSGLIYLNSHASDWANPAMRPYLD 424
Query: 411 KYLAGATGKSTENRMRVLRLI 431
+Y+ G+ G + +R+++L+L+
Sbjct: 425 QYVRGSNGVAAIDRVQLLKLL 445
>gi|37528090|ref|NP_931435.1| hypothetical protein plu4258 [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36787527|emb|CAE16630.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii
TTO1]
Length = 481
Score = 107 bits (266), Expect = 2e-21, Method: Composition-based stats.
Identities = 126/498 (25%), Positives = 219/498 (43%), Gaps = 50/498 (10%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVA--MTYKLAEMDEYKHLMTAT 60
T E+Y+ESLR ++ GE+I N VDHP R ++ +VA Y+ A D+ MT
Sbjct: 4 TGEEYIESLRD-GRTIFLNGEKITNHVDHPAFRNAIRTVASLYDYQAAHADQ----MTFE 58
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVK------MQRL--MGQKTASCFQRCVGMDAFNAIY 112
++ GK+V + L + E L + + MQ +G+ GM + ++
Sbjct: 59 TS-GGKRVGLYWELPTTREKLIARGEAAYAWAMQSCGWLGRSPDHVSAALTGMMTYLEVF 117
Query: 113 STTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLY-LHI 171
Y D+A + Y Y +D D+ + + +P+GDR +PSE + L +
Sbjct: 118 E-EYSKDRA------EALKNYYSYARDKDIYLAFTLVNPQGDRSKTPSEHIKNVFHTLGV 170
Query: 172 VEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREA-DADYAVSFAVPSDAEGVIMIYG 230
+E + GI+V GAK T AV + E ++ ++E D YA+SFA+P + +G I I
Sbjct: 171 LEEKPQGIIVRGAKMLGTAAVLAEEVVVGVFNPLKEGVDDKYALSFALPLNTKG-IKILS 229
Query: 231 RQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVF------MCKEYQFAGMMV 284
R+S +T + + + +F ++A++ FD VFVP ERVF MC+ QF
Sbjct: 230 RKSYETGSNKFDSPL---AHQFDENDAVIYFDDVFVPWERVFVYKNTDMCRR-QFLATGA 285
Query: 285 ERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
+ + K+ L G A + GV + +++ L E+ YA I
Sbjct: 286 DVLMDVQGMARYAVKL---HFLTGLAHQLTETTGVNEFPAVRESLAEL-----ACYATNI 337
Query: 345 ACSSEGTQMKAGN----YMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQ-D 399
G Y+ + L C+ + ++ ++GG ++ +PS D
Sbjct: 338 EGLFRGLISNPDRHNEYYIPNRLQLYACQVALQSTYPKVIESIRKLSGGGVIMLPSNYID 397
Query: 400 FRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+PEI +++K E R+++L+L+ + A + M +G+
Sbjct: 398 LANPEIRDLIEKTQYSTLLPPIE-RVKLLKLVWDAIGSEFASRHTQYEMFYSGAHYVALS 456
Query: 460 MIARQGDLEGKKKLARAI 477
+ Q D + K ++R I
Sbjct: 457 RLYDQYDWDFAKNMSRGI 474
>gi|152988198|ref|YP_001348345.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa PA7]
gi|150963356|gb|ABR85381.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa PA7]
Length = 500
Score = 106 bits (265), Expect = 3e-21, Method: Composition-based stats.
Identities = 121/473 (25%), Positives = 217/473 (45%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y A E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-ALHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRQNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+A+ F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFALVFFARLDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQGFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E+ GG +VT+ + D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLENALGGAPLVTVSAAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|116050203|ref|YP_790980.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa
UCBPP-PA14]
gi|115585424|gb|ABJ11439.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa
UCBPP-PA14]
Length = 500
Score = 105 bits (261), Expect = 8e-21, Method: Composition-based stats.
Identities = 121/473 (25%), Positives = 214/473 (45%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRQNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+AV F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFAVVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQGFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLESALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|145595238|ref|YP_001159535.1| 4-hydroxyphenylacetate 3-hydroxylase [Salinispora tropica CNB-440]
gi|145304575|gb|ABP55157.1| 4-hydroxyphenylacetate 3-hydroxylase [Salinispora tropica CNB-440]
Length = 516
Score = 105 bits (261), Expect = 9e-21, Method: Composition-based stats.
Identities = 104/442 (23%), Positives = 193/442 (43%), Gaps = 27/442 (6%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
+T +YVESLR + +VY GER+++ HP + A Y E ++T +
Sbjct: 10 LTGGEYVESLRD-DREVYLYGERVKDVTTHPAFHNPIRMTARLYDAMHDSEQSSVLTGPT 68
Query: 62 NLTGKQ--VNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEM 118
+ TG+ +RF S +DL + QK + + R G + Y ++
Sbjct: 69 D-TGEPGYTHRFFTTPHSADDL--------IADQKAIAAWARMTYGWMGRSPDYKASFLG 119
Query: 119 DQALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEV 174
++ F + + + Q L + A+ P DR P E AD +++H+ +
Sbjct: 120 TLGANAEFYAPFADNARRWYRESQQKVLYWNHAIVHPPVDRDRPPDEVAD--VFVHVEQE 177
Query: 175 REDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSC 234
+ G++VSGAK TG+ +H I + ++A+ +P +A GV ++ R S
Sbjct: 178 TDAGLIVSGAKVVATGSALTHYSFI-AHYGLPIKRKEFALVATLPMNAPGVKLVC-RPSY 235
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
G+ D +S ++ +++ D+V +P E VF+ E + R
Sbjct: 236 SAAAAVMGSPYDYPLSSRLDENDTILILDKVLIPWENVFIYGEIGKVHLFGAESGFIQRF 295
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
++ GC ++ V + L G A A + G ++ +L E++ + A +
Sbjct: 296 TFHGCTRMAVKLEFLAGLLAKALEIGGTQDFRGVQSRLGEVLAWRNLFWGLSDAAARNPV 355
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIAR--LAEDIAGGLMVTMPSQQDFRHPEIGPIV 409
Q K G + +L + + ++ Y R + +D+A GL+ +DF H +GP +
Sbjct: 356 QWKNGAVLPNLDYG-LAYRWFMQVGYPRVREIILQDVASGLIFVNSGAEDFAHQSVGPYL 414
Query: 410 KKYLAGATGKSTENRMRVLRLI 431
KYL G+ G R++V++L+
Sbjct: 415 DKYLRGSGGTDAVTRVKVMKLL 436
>gi|15597452|ref|NP_250946.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa PAO1]
gi|12644670|sp|O30372|PVCC_PSEAE Pyoverdin chromophore biosynthetic protein pvcC
gi|9948283|gb|AAG05644.1|AE004651_6 pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa PAO1]
Length = 500
Score = 104 bits (260), Expect = 1e-20, Method: Composition-based stats.
Identities = 121/473 (25%), Positives = 213/473 (45%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRHNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+AV F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFAVVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQSFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLESALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|2501842|gb|AAC21673.1| PvcC [Pseudomonas aeruginosa]
Length = 500
Score = 104 bits (259), Expect = 2e-20, Method: Composition-based stats.
Identities = 121/473 (25%), Positives = 212/473 (44%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + D L + A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRHNACAWHRAFADRGLFFNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+AV F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFAVVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQSFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLESALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|152973247|ref|YP_001338393.1| 4-hydroxyphenylacetate catabolism [Klebsiella pneumoniae subsp.
pneumoniae MGH 78578]
gi|150958096|gb|ABR80126.1| 4-hydroxyphenylacetate catabolism [Klebsiella pneumoniae subsp.
pneumoniae MGH 78578]
Length = 520
Score = 103 bits (257), Expect = 2e-20, Method: Composition-based stats.
Identities = 108/495 (21%), Positives = 214/495 (43%), Gaps = 23/495 (4%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTAT 60
+T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 14 LTGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWGT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 73 DTGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANP 129
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A + + + +Q+ L + A+ +P DR P+++ D+Y+ + + + GI+
Sbjct: 130 AFYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRH-KPADEVK-DVYIKLEKETDAGII 187
Query: 181 VSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T + +H ++I + + + D+A+ F P DAEGV +I R S +
Sbjct: 188 VSGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDAEGVKLI-SRASYEMVAG 246
Query: 240 EEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHR 292
G+ D +S F ++A++V D+V +P E V + C+ + G Y
Sbjct: 247 ATGSPYDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPL 303
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
Q+ V + D + + + G + ++ L E++ +A + SE T
Sbjct: 304 QACVRLAVKL-DFITALLKRSLECTGTLEFRGVQADLGEVVAWRNMFWALSDSMCSEATP 362
Query: 353 MKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKK 411
G ++ D + +I + E ++ GL+ S +D +P+I + K
Sbjct: 363 WVNGAWLPDHAALQTYRVMAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAK 422
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKK 471
Y+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 423 YVRGSNGMDHVERIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG-- 480
Query: 472 KLARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 481 NMDKMMAMVDRCLSE 495
>gi|84327292|ref|ZP_00975313.1| COG2368: Aromatic ring hydroxylase [Pseudomonas aeruginosa 2192]
gi|126194074|gb|EAZ58137.1| pyoverdine biosynthesis protein PvcC [Pseudomonas aeruginosa 2192]
Length = 500
Score = 103 bits (257), Expect = 3e-20, Method: Composition-based stats.
Identities = 120/473 (25%), Positives = 214/473 (45%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRQNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+A+ F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFALVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQGFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLEGALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|15920956|ref|NP_376625.1| hypothetical phenol hydroxylase [Sulfolobus tokodaii str. 7]
gi|15621740|dbj|BAB65734.1| 494aa long hypothetical phenol hydroxylase [Sulfolobus tokodaii
str. 7]
Length = 494
Score = 103 bits (257), Expect = 3e-20, Method: Composition-based stats.
Identities = 111/470 (23%), Positives = 209/470 (44%), Gaps = 39/470 (8%)
Query: 5 EQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLT 64
E Y++S++ + VY+ GE +E+ +H + + +VA Y L EY + +
Sbjct: 9 EDYIKSIKAHHPVVYYEGEVVEDITEHQAFKIPVRTVAKYYDLHWDPEYSKYLRVYNPDV 68
Query: 65 GKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGM--DAFNAIYSTTYE----- 117
G++ + ++ +DL K++ + K ++ G D N + Y
Sbjct: 69 GEETSISFLRPRNKQDL---AKLRDGL-IKIYDFYRGFFGRSPDYLNVWTTVFYAHAEDY 124
Query: 118 MDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
+ G+ + + IE + NDL A+ P DR PS+ DP + + IVE + D
Sbjct: 125 FGKHFGSKFMENMIEIYREATKNDLFYTHAIVAPMYDRSRPPSQWEDPYIQVGIVEEKPD 184
Query: 178 GIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTR 237
G++V GA T S +P I R+ D YA+ F++P++ +GV + R+ R
Sbjct: 185 GVIVRGAAMLSTAGPYSEMLWYLPNI-RRDTDPRYAIYFSIPTETKGVKFL-ARRGFPPR 242
Query: 238 KMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCK------EYQFAGMMVERFAGY 290
EG + + +S F +A++VFD VFVP +R+ K + + + + + +
Sbjct: 243 ---EGGEFEYPISSRFEESDAILVFDNVFVPYDRIIFFKKPELIEDLMWHTVSLRGWFNW 299
Query: 291 HR--QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEM---IHLNETLYACGIA 345
H Q Y K L G A A+ G+ ++++K+ E+ + LNE +
Sbjct: 300 HFVIQHYSRLK-----FLAGLAIAVAEAAGINNFINVQEKIGEILIYVALNEAALYASVE 354
Query: 346 CSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPE 404
+ E + + I + ++ + + R EI RL I+ G + +P+ +DF +PE
Sbjct: 355 RAQELPNIARPDPYISISASHFNMKAVPR-ANEILRL---ISAGSSIPVPAGIKDFENPE 410
Query: 405 IGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
++ KY+A G + R+++ L+ ++ + + Y G P
Sbjct: 411 ERRLLDKYMA-MKGLNALERVKLFNLLWDVIGSESGMRYEQYDRFSRGDP 459
>gi|75198162|ref|ZP_00708232.1| COG2368: Aromatic ring hydroxylase [Escherichia coli HS]
gi|75515537|ref|ZP_00737694.1| COG2368: Aromatic ring hydroxylase [Escherichia coli 53638]
gi|124531569|ref|ZP_01701800.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Escherichia coli B]
gi|124498501|gb|EAY46012.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Escherichia coli B]
gi|157069472|gb|ABV08727.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Escherichia coli HS]
Length = 520
Score = 103 bits (256), Expect = 3e-20, Method: Composition-based stats.
Identities = 109/494 (22%), Positives = 213/494 (43%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y+ + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA+GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDADGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|74314781|ref|YP_313200.1| 4-hydroxyphenylacetate 3-monooxygenase [Shigella sonnei Ss046]
gi|73858258|gb|AAZ90965.1| 4-hydroxyphenylacetate 3-monooxygenase [Shigella sonnei Ss046]
Length = 520
Score = 102 bits (255), Expect = 5e-20, Method: Composition-based stats.
Identities = 109/494 (22%), Positives = 212/494 (42%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y+ + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDANGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHATLQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|84321030|ref|ZP_00969395.1| COG2368: Aromatic ring hydroxylase [Pseudomonas aeruginosa C3719]
Length = 448
Score = 102 bits (254), Expect = 5e-20, Method: Composition-based stats.
Identities = 117/449 (26%), Positives = 205/449 (45%), Gaps = 34/449 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRQNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+A+ F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFALVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G E FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYAESGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQGFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLESALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENIT 435
+V Y GA E R+++ +LI + T
Sbjct: 410 RLVDSYYRGAE-LEPEQRLKLFKLIWDAT 437
>gi|75258427|ref|ZP_00729858.1| COG2368: Aromatic ring hydroxylase [Escherichia coli E22]
Length = 520
Score = 102 bits (254), Expect = 5e-20, Method: Composition-based stats.
Identities = 109/494 (22%), Positives = 212/494 (42%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y+ + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDANGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|107101702|ref|ZP_01365620.1| hypothetical protein PaerPA_01002746 [Pseudomonas aeruginosa PACS2]
Length = 500
Score = 102 bits (254), Expect = 5e-20, Method: Composition-based stats.
Identities = 119/473 (25%), Positives = 214/473 (45%), Gaps = 34/473 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR +VY GER+ + H R + S+A Y E + ++T
Sbjct: 9 LMTGADYLDSLRD-GRQVYLNGERVADVTRHRAFRNACRSIAGLYD-GLHGEQRDVLTRV 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTT 115
+ G++ +RF Q+ EDL L ++ C+ R + A + +
Sbjct: 67 -DAQGRRSHRFFTPAQNAEDL--------LGAREAIGCWSRMTYGFMGRTPDYKAAFMSG 117
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
E Y + + + D L ++ A+ +P DR + E D +++H+
Sbjct: 118 LEAGAGFYGDYRQNACAWHRAFADRGLFLNHAIINPPLDRSKAIHEMRD--VFVHVERET 175
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADA----DYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSGAK TG+ ++ + P +A + +A D+A+ F D G+ ++ R
Sbjct: 176 DQGIVVSGAKMLATGSAITNATFVAP-VASAQMEAGKAEDFALVFFARMDNPGLRLMC-R 233
Query: 232 QSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVER-FAG 289
S + R D L +S F ++++++FD+ +P E V + ++ + A G + FA
Sbjct: 234 PSYEERA-SSPFDYPL-SSRFDENDSVLLFDKALIPWEDVLVYRDLRRATGFYADSGFAN 291
Query: 290 -YHRQSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y+ QS G ++GV +++IG +L NG I+ L E+I L L A A +
Sbjct: 292 LYNFQS--GIRLGVKLELMIGLLSLGVRANGTQGFRGIQAALGELIALQHLLQALTTAMA 349
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPSQQDFRHPEIG 406
+ + AG+ + L AN + + ++ + L E GG +VT+ D R E
Sbjct: 350 RDPERNAAGSAVPRLEYANALRIQVPQIWKRVRELLESALGGAPLVTVSGAADLRDGEAR 409
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI 459
+V Y GA + E R+++ +LI + T + H +G+ + R+
Sbjct: 410 RLVDSYYRGAELEP-EQRLKLFKLIWDATGSEFGARHAVYESHYSGNAEQIRL 461
>gi|38112622|gb|AAR11357.1| HpaB [Escherichia coli]
Length = 520
Score = 102 bits (254), Expect = 6e-20, Method: Composition-based stats.
Identities = 109/494 (22%), Positives = 212/494 (42%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYTKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA+GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVXGENPDFALMFVAPMDADGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|62179619|ref|YP_216036.1| 4-hydroxyphenylacetate catabolism [Salmonella enterica subsp.
enterica serovar Choleraesuis str. SC-B67]
gi|62127252|gb|AAX64955.1| 4-hydroxyphenylacetate catabolism [Salmonella enterica subsp.
enterica serovar Choleraesuis str. SC-B67]
Length = 520
Score = 102 bits (253), Expect = 7e-20, Method: Composition-based stats.
Identities = 108/495 (21%), Positives = 214/495 (43%), Gaps = 23/495 (4%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTAT 60
+T E+Y++SL+ ++Y GER+++ HP R + SVA Y L + L T
Sbjct: 14 LTGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPSMQDTLCWNT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 73 DTGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANP 129
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A + + + +Q+ L + A+ +P DR P+++ D+Y+ + + + GI+
Sbjct: 130 AFYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRH-KPADEVK-DVYIKLEKETDAGII 187
Query: 181 VSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T + +H ++I + + + D+A+ F P DAEGV +I R S +
Sbjct: 188 VSGAKVVATNSTLTHYNMIGFGSAQVMGENPDFALMFVAPMDAEGVKLI-SRASYEMVAG 246
Query: 240 EEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHR 292
G+ D +S F ++A++V D+V +P E V + C+ + G Y
Sbjct: 247 ATGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPL 303
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
Q+ V + D + + + G + ++ L E++ +A + SE T
Sbjct: 304 QACVRLAVKL-DFITALLKKSLECTGTVEFRGVQADLGEVVAWRNMFWALSDSMCSEATP 362
Query: 353 MKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKK 411
G ++ D + +I + E ++ GL+ S +D +P+I + K
Sbjct: 363 WVNGAWLPDHAALQTYRVMAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAK 422
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKK 471
Y+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 423 YVRGSNGMDHVERIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG-- 480
Query: 472 KLARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 481 NMDKMMAMVDRCLSE 495
>gi|16764457|ref|NP_460072.1| 4-hydroxyphenylacetate catabolism [Salmonella typhimurium LT2]
gi|16419614|gb|AAL20031.1| 4-hydroxyphenylacetate catabolism protein [Salmonella typhimurium
LT2]
Length = 520
Score = 102 bits (253), Expect = 7e-20, Method: Composition-based stats.
Identities = 108/495 (21%), Positives = 214/495 (43%), Gaps = 23/495 (4%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTAT 60
+T E+Y++SL+ ++Y GER+++ HP R + SVA Y L + L T
Sbjct: 14 LTGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPSMQDTLCWNT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 73 DTGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANP 129
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
A + + + +Q+ L + A+ +P DR P+++ D+Y+ + + + GI+
Sbjct: 130 AFYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRH-KPADEVK-DVYIKLEKETDAGII 187
Query: 181 VSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T + +H ++I + + + D+A+ F P DAEGV +I R S +
Sbjct: 188 VSGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDAEGVKLI-SRASYEMVAG 246
Query: 240 EEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHR 292
G+ D +S F ++A++V D+V +P E V + C+ + G Y
Sbjct: 247 ATGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPL 303
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
Q+ V + D + + + G + ++ L E++ +A + SE T
Sbjct: 304 QACVRLAVKL-DFITALLKKSLECTGTVEFRGVQADLGEVVAWRNMFWALSDSMCSEATP 362
Query: 353 MKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKK 411
G ++ D + +I + E ++ GL+ S +D +P+I + K
Sbjct: 363 WVNGAWLPDHAALQTYRVMAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAK 422
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKK 471
Y+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 423 YVRGSNGMDHVERIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG-- 480
Query: 472 KLARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 481 NMDKMMAMVDRCLSE 495
>gi|20454959|sp|Q57160|HPAB_ECOLI 4-hydroxyphenylacetate 3-monooxygenase oxygenase component (4-HPA
3-monooxygenase large component) (4-HPA 3-hydroxylase)
gi|452841|emb|CAA82321.1| 4-hydroxyphenylacetic hydroxylase [Escherichia coli]
gi|757834|emb|CAA86048.1| component B of the 4HPA-hydroxylase [Escherichia coli]
Length = 520
Score = 101 bits (252), Expect = 1e-19, Method: Composition-based stats.
Identities = 115/500 (23%), Positives = 218/500 (43%), Gaps = 35/500 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + A + G Y + A
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRHE-------RDAIAEWSRLSYGWMGRTPDYKAAFGC--A 124
Query: 122 LGTT--YHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
LG T ++ +F + + +Q+ L + A+ +P DR L P+++ D+Y+ + +
Sbjct: 125 LGGTPGFYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKET 182
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSC 234
+ GI+VSGAK T + +H ++I + + + D+A+ F P DA+GV +I R S
Sbjct: 183 DAGIIVSGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDADGVKLI-SRASY 241
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERF 287
+ G+ D +S F ++A++V D V +P E V + C+ + G
Sbjct: 242 EMVAGATGSPYDYPLSSRFDENDAILVMDNVLIPWENVLLYRDFDRCRRWTMEGGFARM- 300
Query: 288 AGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y Q+ V + D + + + G + ++ L E++ T +A +
Sbjct: 301 --YPLQACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMC 357
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIG 406
SE T G Y+ D + +I + E ++ GL+ S +D +P+I
Sbjct: 358 SEATPWVNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQID 417
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGD 466
+ KY+ G+ G R+++L+L+ + + ++ +GS R+ RQ
Sbjct: 418 QYLAKYVRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQ 477
Query: 467 LEGKKKLARAIAHIDESLDK 486
G + + +A +D L +
Sbjct: 478 SSG--NMDKMMAMVDRCLSE 495
>gi|119881746|ref|ZP_01648039.1| 4-hydroxyphenylacetate 3-hydroxylase [Salinispora arenicola CNS205]
gi|119825466|gb|EAX28021.1| 4-hydroxyphenylacetate 3-hydroxylase [Salinispora arenicola CNS205]
Length = 525
Score = 101 bits (252), Expect = 1e-19, Method: Composition-based stats.
Identities = 116/453 (25%), Positives = 198/453 (43%), Gaps = 49/453 (10%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
+T ++YVESLR + +VY G+R+ + HP R + A Y + + ++TA +
Sbjct: 20 LTGDEYVESLRD-DRQVYVYGDRVRDVTAHPAFRNPVRMTARLYDALHDPQTRPVLTAPT 78
Query: 62 NLTGKQ--VNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
+ TG +RF +S DL V QR + + + A + T +
Sbjct: 79 D-TGSDGYTHRFFTTARSVADL---VADQRAIAAWARLSYGWMGRAPDYKAAFLGTLGAN 134
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ + + Q+ L + A+ P DR P E D +++H+ + G+
Sbjct: 135 AEYYAPFADNARRWYRESQEKVLYWNHAIVHPPVDRSRPPDEVRD--VFIHVERETDAGL 192
Query: 180 VVSGAKAHQTGAVNSH----EHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
VVSGAK T + +H H +P + RE +A+ VP DA G+ +I R S
Sbjct: 193 VVSGAKVVATASALTHYNFLAHYGLP-VRKRE----FALVATVPMDAPGMKLIC-RPSYA 246
Query: 236 TRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVF----MCKEYQFAGM--MVERFA 288
G+ D +S +++++V DRV +P E VF + K FAG ERF
Sbjct: 247 ATAAVMGSPFDYPLSSRLDENDSILVLDRVLIPWENVFIYGDLAKVQMFAGQSGFTERF- 305
Query: 289 GYHRQSYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIAC 346
++ GC ++ V + L G A A + G + ++ +L E++ + A
Sbjct: 306 -----TFHGCTRLAVKLEFLAGLLAKAVELTGTAEFRGVQSRLGEVLAWRNLFWGLSDAA 360
Query: 347 SSEGTQMKAGNYMIDLLLAN----VCKQNITRLPY----EIARLAEDIAGGLMVTMPSQQ 398
+ K G LL N + + ++ Y EIA +D+A GL+ S
Sbjct: 361 ARNPVPWKNG-----ALLPNPQYGMAYRWFMQIGYPRIREIA--MQDVASGLIYVNSSAD 413
Query: 399 DFRHPEIGPIVKKYLAGATGKSTENRMRVLRLI 431
DF +P+I P + YL G+ G R+++++L+
Sbjct: 414 DFHNPDIRPYLDTYLRGSGGADAVERVKLMKLL 446
>gi|111019371|ref|YP_702343.1| phenol 2-monoxygenase, oxygenase component [Rhodococcus sp. RHA1]
gi|110818901|gb|ABG94185.1| phenol 2-monoxygenase, oxygenase component [Rhodococcus sp. RHA1]
Length = 538
Score = 101 bits (251), Expect = 1e-19, Method: Composition-based stats.
Identities = 104/443 (23%), Positives = 194/443 (43%), Gaps = 29/443 (6%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEY-KHLMTAT 60
MT ++Y+ESLR + +++ GER+E+ HP R + A Y E+ + T T
Sbjct: 36 MTGDEYIESLRD-DREIWLHGERVEDVTTHPAFRNPIRMTARLYDSMHTGEHVDKVTTPT 94
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G F +S++DL + + T R + A + T ++
Sbjct: 95 DTGNGGVTMPFFKAPKSSDDLLKERDAIATWARMTYGWMGRS---PDYKASFLGTLHANK 151
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + K Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 152 ELYSPFQDNAERWYKESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDAGLI 209
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + ++A+ VP DA GV +I R S
Sbjct: 210 VSGAKVVATGSAITNYNFI-AHYGLPIKKKEFALICTVPMDAPGVKLIC-RSSFTQNAAV 267
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQS----- 294
G D +S ++ + +FD+V VP E VFM + V++ G+ QS
Sbjct: 268 MGTPFDYPLSSRMDENDTIFIFDKVLVPWENVFMYGD-------VDKINGFFPQSGFLPR 320
Query: 295 --YGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEG 350
+ GC ++ V D + G A D G ++ ++ E+I ++ +
Sbjct: 321 FTFQGCTRLAVKLDFIAGMLMKALDATGAGGFRGVQTRVGEVIGWRNLFWSL-TESMARN 379
Query: 351 TQMKAGNYMIDLLLANVCKQN--ITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPI 408
+ G+ +I L + + I P + +D+A GL+ S +DF+ P++ P
Sbjct: 380 PEPWIGDTVIPKLEYGLTYRMFMIQGYPRIKEIIEQDVASGLIYLPSSARDFKSPDVRPY 439
Query: 409 VKKYLAGATGKSTENRMRVLRLI 431
+ KY+ G+ G + R+++++ +
Sbjct: 440 LDKYVRGSDGMTAVERVKIMKAL 462
>gi|3002548|gb|AAC08739.1| 4-hydroxyphenylacetic acid hydroxylase [Photorhabdus luminescens]
Length = 520
Score = 101 bits (251), Expect = 1e-19, Method: Composition-based stats.
Identities = 110/481 (22%), Positives = 210/481 (43%), Gaps = 23/481 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R S S+ Y L + + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNSAASIGQLYDALHAPETHDTLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F S +DL+ QR A ++ G + Y +
Sbjct: 74 TGNGGYTHKFFRFATSVDDLRQ----QR---DAIAEWSRQTYGWMGRSPDYKAAFGNVLG 126
Query: 122 LGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
Y+ +F + + K +Q+ + + A+ +P DR P++Q D+Y+ + + +
Sbjct: 127 AFPEYYGQFADNARTWYKRIQETGVYFNHAIVNPPIDRH-KPADQTR-DVYIKLEKETDA 184
Query: 178 GIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDT 236
GI+VSGAK T + +H + I + + + + D+A+ F P DAEGV +I R S +
Sbjct: 185 GIIVSGAKVVATNSALTHYNFIGLGSAQVMGDNPDFALMFVAPMDAEGVKLI-SRGSYEL 243
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFA---GMMVERFAGYHR 292
G+ D +S F ++A++V D+V +P E V + +++ A + + Y
Sbjct: 244 VAGATGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRARNWAIQAGFTSLYPL 303
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
Q+ V + D + + + GV + ++ L E++ +A +E +
Sbjct: 304 QACVRLAVKL-DFITALLQRSLECTGVIEFRGVQANLGEVVAWRNLFWALSDCMWAEANR 362
Query: 353 MKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKK 411
K+G Y+ D + +I + E ++ GL+ S +D +PEI + +
Sbjct: 363 GKSGAYLPDTQAIQTYRVMAPTAYTKIKNIIESNVTSGLIYLPSSVRDMNNPEIDKYLAR 422
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKK 471
Y+ G+ G R+++L+L+ + + ++ AGS R+ R G
Sbjct: 423 YVRGSNGIDHIERIKILKLMWDAIGSEFGGRHELYEINYAGSQDEIRMQCLRHAHGSGNM 482
Query: 472 K 472
K
Sbjct: 483 K 483
>gi|86279133|gb|ABC88666.1| 4-coumarate 3-hydroxylase [Saccharothrix espanaensis]
Length = 512
Score = 101 bits (251), Expect = 1e-19, Method: Composition-based stats.
Identities = 112/462 (24%), Positives = 205/462 (44%), Gaps = 47/462 (10%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTAT 60
MT E+Y+ESLR +VY GER+++ H R S+ S+A Y L + L T
Sbjct: 18 MTGEEYLESLRD-GREVYIYGERVDDVTTHLAFRNSVRSIARLYDVLHDPASEGVLRVPT 76
Query: 61 SNLTGKQVNRFCHLHQSTEDL----KDKVKMQRL----MGQKTASCFQRCVGMDAFNAIY 112
G + F +S+EDL + V QRL MG+ + A +
Sbjct: 77 DTGNGGFTHPFFKTARSSEDLVAAREAIVGWQRLVYGWMGRTPD-----------YKAAF 125
Query: 113 STTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIV 172
T + + + + + Q+ L + A+ P DR P+++ D+ +H+
Sbjct: 126 FGTLDANAEFYGPFEANARRWYRDAQERVLYFNHAIVHPPVDRD-RPADRT-ADICVHVE 183
Query: 173 EVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQ 232
E + G++VSGAK TG+ ++ +LI + D + + F VP ++ G+ +I R
Sbjct: 184 EETDSGLIVSGAKVVATGSAMTNANLI-AHYGLPVRDKKFGLVFTVPMNSPGLKLIC-RT 241
Query: 233 SCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM-----CKEYQFAGMMVER 286
S + +G+ D +S ++++++FDRV VP E VFM + +ER
Sbjct: 242 SYELMVATQGSPFDYPLSSRLDENDSIMIFDRVLVPWENVFMYDAGAANSFATGSGFLER 301
Query: 287 FAGYHRQSYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGI 344
F ++ GC ++ V D + G A + G ++ ++ E+++ + +
Sbjct: 302 F------TFHGCTRLAVKLDFIAGCVMKAVEVTGTTHFRGVQAQVGEVLNWRDVFWGLSD 355
Query: 345 ACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDI----AGGLMVTMPSQQDF 400
A + G+ +L N T + R+ E I GL+ S D+
Sbjct: 356 AMAKSPNSWVGGSVQPNL---NYGLAYRTFMGVGYPRIKEIIQQTLGSGLIYLNSSAADW 412
Query: 401 RHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG 442
++P++ P + +YL G+ G +R+++L+L+ + +GT G
Sbjct: 413 KNPDVRPYLDRYLRGSRGIQAIDRVKLLKLLWD-AVGTEFAG 453
>gi|20454956|sp|Q48440|HPAB_KLEOX 4-hydroxyphenylacetate 3-monooxygenase oxygenase component (4-HPA
3-monooxygenase large component) (4-HPA 3-hydroxylase)
gi|974146|gb|AAC37120.1| 4-hydroxyphenylacetate-3-hydroxylase
Length = 520
Score = 101 bits (251), Expect = 1e-19, Method: Composition-based stats.
Identities = 110/497 (22%), Positives = 221/497 (44%), Gaps = 27/497 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKH-LMTAT 60
+T E+Y++SL+ ++Y GER+++ HP R + SVA Y E ++ L T
Sbjct: 14 LTGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHNPELQNTLCWGT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 73 DTGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGGGLGANP 129
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
+ + ++ +Q+ L + A+ +P DR P+++ D+Y+ + + + GI+
Sbjct: 130 GFYGQFEQNARDWYTRIQETGLYFNHAIVNPPIDRH-KPADEVK-DVYIKLEKETDAGII 187
Query: 181 VSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
VSGAK T + +H ++I + + + D+A+ F P DAEG +I R S +
Sbjct: 188 VSGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDAEGDKLI-SRASYELVAG 246
Query: 240 EEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHR 292
G+ D +S F ++A++V D V +P E V + C+ + G Y
Sbjct: 247 ATGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPL 303
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
Q+ V + D + + + G + ++ +L E++ +A + +E T
Sbjct: 304 QACVRLAVKL-DFITALLKRSLECTGTLEFRGVQAELGEVVAWRNMFWALSDSMCAEATP 362
Query: 353 MKAGNYMIDLLLANVCKQNITRLPY-EIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVK 410
G Y+ D + + +PY +I + E + GL+ S +D +P+I +
Sbjct: 363 WVNGAYLPDHAALQTYRV-MAPMPYAKIKNIIERSVTSGLIYLPSSARDLNNPQINDTLA 421
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQGDLEG 469
KY+ G+ G R+++L+L+ + +G+ G + ++ +GS R+ RQ G
Sbjct: 422 KYVRGSNGMDHVERIKILKLMWD-AIGSEFGGCHELYEINYSGSQDEIRLQCLRQAQSSG 480
Query: 470 KKKLARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 481 --NMDKMMAMVDRCLSE 495
>gi|75179307|ref|ZP_00699311.1| COG2368: Aromatic ring hydroxylase [Shigella boydii BS512]
Length = 520
Score = 100 bits (250), Expect = 2e-19, Method: Composition-based stats.
Identities = 108/494 (21%), Positives = 212/494 (42%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S +DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSADDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y+ + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA+GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDADGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G +++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQHIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|76260468|ref|ZP_00768103.1| 4-hydroxyphenylacetate 3-hydroxylase [Chloroflexus aurantiacus
J-10-fl]
gi|76164599|gb|EAO58744.1| 4-hydroxyphenylacetate 3-hydroxylase [Chloroflexus aurantiacus
J-10-fl]
Length = 531
Score = 100 bits (250), Expect = 2e-19, Method: Composition-based stats.
Identities = 100/445 (22%), Positives = 196/445 (44%), Gaps = 23/445 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTY-KLAEM---------- 50
M +Y++SLR + +YF GER+++ HP R S VA Y +L E+
Sbjct: 18 MNGREYLDSLRD-DRVIYFQGERVKDVTTHPAFRNSARMVARWYDRLHELHQEDVARGGP 76
Query: 51 DEYKHLMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNA 110
+++K M T +G + F ++ DL V+ + + + + + + A
Sbjct: 77 EDWKWTM-PTDTGSGGWTHPFFVGSRTVADL---VRARDTIAELQRAVYGWMGRAPDYKA 132
Query: 111 IYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
++ T + Y + + + Q+ + + A+ +P DR P E D +Y+H
Sbjct: 133 AFTGTLGANAEFYAPYQENARRWYRKTQEELIYWNHAIVNPPIDRNRPPDEVRD--VYMH 190
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYG 230
+ + G++VSGAK TG+ +H + I + + +A+ FAVP +A G+ +I
Sbjct: 191 VERETDAGLIVSGAKVVATGSALTHVNFIAHYGPLPIKEKQFALIFAVPMNAPGIKLI-A 249
Query: 231 RQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAG 289
R S + G+ D +S +++++VFD+V +P E VF+ + +
Sbjct: 250 RTSYEYNAAVTGSPFDYPLSSRLDENDSILVFDQVLIPWENVFVYGDIEKVNTFFPLSGF 309
Query: 290 YHR-QSYGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
HR +GG + V D + G A + GV + ++ +L E++ + A
Sbjct: 310 GHRFPLHGGVRFAVKLDFITGLMLKAVEATGVAEFRGVQARLGEIVTYRNLFWQLTEAMV 369
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIG 406
G + +L A + +I L E ++ +PS D ++PE+
Sbjct: 370 RNPMPWVDGYLLPNLEAAFAYRVMAPDAYVKIKDLIEKDVASALIYLPSHAADLKNPEVR 429
Query: 407 PIVKKYLAGATGKSTENRMRVLRLI 431
+ +++ G+ G S R+++++L+
Sbjct: 430 GYLDRFVRGSNGYSALERIKLMKLL 454
>gi|153948091|ref|YP_001401326.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Yersinia pseudotuberculosis IP 31758]
gi|152959586|gb|ABS47047.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Yersinia pseudotuberculosis IP 31758]
Length = 520
Score = 100 bits (248), Expect = 3e-19, Method: Composition-based stats.
Identities = 116/498 (23%), Positives = 220/498 (44%), Gaps = 35/498 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T ++Y++SL+ ++Y GER++N HP R + S+ Y L + ++ L T
Sbjct: 15 THKEYLDSLQD-GREIYIYGERVKNVTTHPAFRNAAASIGQLYDALHDPQSHEQLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F S +L+ QR A ++ G + Y +
Sbjct: 74 TGNGGYTHKFFRYATSPAELRQ----QR---DAIAHWSRQNYGWMGRSPDYKAAFGSVLG 126
Query: 122 LGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
++ +F + + + +Q++ L + A+ +P DR S E D +Y+HI + +
Sbjct: 127 AFPEFYGQFADNARNWYQRIQESGLYFNHAIVNPPLDRHKSADEVKD--VYIHIEKETDA 184
Query: 178 GIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDT 236
GI+VSGAK T + +H + I + + D D+A+ F P DA+G+ +I R S +
Sbjct: 185 GIIVSGAKVVATNSALTHYNFIGFGSAQVMGEDPDFALMFVAPMDADGMKLI-SRGSYEL 243
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAG 289
G+ D +S F ++A++V D V +P E + + C+ + G F
Sbjct: 244 MVGATGSPFDYPLSSRFDENDAILVMDNVLIPWENILIYRDFDRCRRWSTQGGFARLFP- 302
Query: 290 YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSE 349
+ G K+ L+ + + G + ++ L E++ ++A A +E
Sbjct: 303 LQACTRLGVKLDFITALLKKSLMC---TGSLEFRGVQADLGEVVAWRNVIWALSDAMCAE 359
Query: 350 GTQMKAGNYMIDLLLANVCKQNITRLPY-EIARLAE-DIAGGLMVTMPSQQDFRHPEIGP 407
G Y+ DL + I + Y +I + E +A GL+ S +D ++P I
Sbjct: 360 AKPWVNGAYLPDLAALQAYRV-IAPMAYCKIKNIIERTLASGLIYLPSSVRDLQNPAIDK 418
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQGD 466
+ +Y+ G+ G R++VL+L+ + +G+ G + ++ AGS R+ RQ
Sbjct: 419 YLSRYVRGSNGIDHVERIKVLKLMWD-AMGSEFGGRHELYEINYAGSQDEIRLQCLRQA- 476
Query: 467 LEGKKKLARAIAHIDESL 484
+G + + +A +D L
Sbjct: 477 -QGDGSMDQMMAMVDRCL 493
>gi|16122023|ref|NP_405336.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis CO92]
gi|22126421|ref|NP_669844.1| component B of 4-hydroxyphenylacetic acid-hydroxylase [Yersinia
pestis KIM]
gi|45441441|ref|NP_992980.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis biovar
Microtus str. 91001]
gi|51595981|ref|YP_070172.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pseudotuberculosis
IP 32953]
gi|77635122|ref|ZP_00797210.1| COG2368: Aromatic ring hydroxylase [Yersinia pestis Angola]
gi|89104598|ref|ZP_01177137.1| COG2368: Aromatic ring hydroxylase [Yersinia pestis biovar
Orientalis str. IP275]
gi|108807137|ref|YP_651053.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Antiqua]
gi|108812515|ref|YP_648282.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Nepal516]
gi|145598642|ref|YP_001162718.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Pestoides
F]
gi|149366282|ref|ZP_01888317.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis CA88-4125]
gi|21959410|gb|AAM86095.1|AE013856_9 putative component B of 4-hydroxyphenylacetic acid-hydroxylase
[Yersinia pestis KIM]
gi|45436302|gb|AAS61857.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis biovar
Microtus str. 91001]
gi|51589263|emb|CAH20884.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pseudotuberculosis
IP 32953]
gi|108776163|gb|ABG18682.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Nepal516]
gi|108779050|gb|ABG13108.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Antiqua]
gi|115347502|emb|CAL20410.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis CO92]
gi|145210338|gb|ABP39745.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis Pestoides
F]
gi|149292695|gb|EDM42769.1| 4-hydroxyphenylacetate 3-monooxygenase [Yersinia pestis CA88-4125]
Length = 520
Score = 100 bits (248), Expect = 3e-19, Method: Composition-based stats.
Identities = 116/498 (23%), Positives = 220/498 (44%), Gaps = 35/498 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T ++Y++SL+ ++Y GER++N HP R + S+ Y L + ++ L T
Sbjct: 15 THKEYLDSLQD-GREIYIYGERVKNVTTHPAFRNAAASIGQLYDALHDPQSHEQLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F S +L+ QR A ++ G + Y +
Sbjct: 74 TGNGGYTHKFFRYATSPAELRQ----QR---DAIAHWSRQNYGWMGRSPDYKAAFGSVLG 126
Query: 122 LGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
++ +F + + + +Q++ L + A+ +P DR S E D +Y+HI + +
Sbjct: 127 AFPEFYGQFADNARNWYQRIQESGLYFNHAIVNPPLDRHKSADEVKD--VYIHIEKETDA 184
Query: 178 GIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDT 236
GI+VSGAK T + +H + I + + D D+A+ F P DA+G+ +I R S +
Sbjct: 185 GIIVSGAKVVATNSALTHYNFIGFGSAQVMGEDPDFALMFVAPMDADGMKLI-SRGSYEL 243
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAG 289
G+ D +S F ++A++V D V +P E + + C+ + G F
Sbjct: 244 MVGATGSPFDYPLSSRFDENDAILVMDNVLIPWENILIYRDFDRCRRWSTQGGFARLFP- 302
Query: 290 YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSE 349
+ G K+ L+ + + G + ++ L E++ ++A A +E
Sbjct: 303 LQACTRLGVKLDFITALLKKSLMC---TGSLEFRGVQADLGEVVAWRNVIWALSDAMCAE 359
Query: 350 GTQMKAGNYMIDLLLANVCKQNITRLPY-EIARLAE-DIAGGLMVTMPSQQDFRHPEIGP 407
G Y+ DL + I + Y +I + E +A GL+ S +D ++P I
Sbjct: 360 AKPWVNGAYLPDLAALQAYRV-IAPMAYCKIKNIIERTLASGLIYLPSSVRDLQNPAIDK 418
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQGD 466
+ +Y+ G+ G R++VL+L+ + +G+ G + ++ AGS R+ RQ
Sbjct: 419 YLSRYVRGSNGIDHVERIKVLKLMWD-AMGSEFGGRHELYEINYAGSQDEIRLQCLRQA- 476
Query: 467 LEGKKKLARAIAHIDESL 484
+G + + +A +D L
Sbjct: 477 -QGDGSMDQMMAMVDRCL 493
>gi|82546699|ref|YP_410646.1| 4-hydroxyphenylacetate 3-monooxygenase [Shigella boydii Sb227]
gi|81248110|gb|ABB68818.1| 4-hydroxyphenylacetate 3-monooxygenase [Shigella boydii Sb227]
Length = 520
Score = 100 bits (248), Expect = 3e-19, Method: Composition-based stats.
Identities = 108/494 (21%), Positives = 211/494 (42%), Gaps = 23/494 (4%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R + SVA Y E + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPEMQDSLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F + +S DL+ + + + R + A + +
Sbjct: 74 TGSGGYTHKFFRVAKSANDLRQQRDAIAEWSRLSYGWMGR---TPDYKAAFGCALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + + +Q+ L + A+ +P DR L P+++ D+Y+ + + + GI+V
Sbjct: 131 FYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRHL-PTDKVK-DVYIKLEKETDAGIIV 188
Query: 182 SGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H ++I + + + D+A+ F P DA+GV +I R S +
Sbjct: 189 SGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDADGVKLI-SRASYEMVAGA 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQ 293
G+ D +S F ++A++V D V +P E V + C+ + G Y Q
Sbjct: 248 TGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQ 304
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
+ V + D + + + G + ++ L E++ T +A + SE T
Sbjct: 305 ACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRNTFWALSDSMCSEATPW 363
Query: 354 KAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKY 412
G Y+ D + +I + E ++ GL+ S +D +P+I + KY
Sbjct: 364 VNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKY 423
Query: 413 LAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G+ G +++L+L+ + + ++ +GS R+ RQ G
Sbjct: 424 VRGSNGMDHVQHIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--N 481
Query: 473 LARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 482 MDKMMAMVDRCLSE 495
>gi|111019505|ref|YP_702477.1| phenol hydroxylase, oxygenase component [Rhodococcus sp. RHA1]
gi|110819035|gb|ABG94319.1| phenol hydroxylase, oxygenase component [Rhodococcus sp. RHA1]
Length = 538
Score = 99.8 bits (247), Expect = 3e-19, Method: Composition-based stats.
Identities = 101/436 (23%), Positives = 191/436 (43%), Gaps = 15/436 (3%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEY-KHLMTAT 60
MT ++Y+ESLR + ++Y GER+++ HP R + A Y E+ L T T
Sbjct: 36 MTGDEYIESLRD-DREIYLHGERVKDVTTHPAFRNPIRMTARLYDAMHTGEHVDTLTTPT 94
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G F ++++DL + T R + A + T ++
Sbjct: 95 DTGSGGVTMPFFRAPKNSDDLLKDRDAIATWARMTYGWMGRS---PDYKASFLGTLHANK 151
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + K Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 152 ELYSPFQDNAERWYKESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDAGLI 209
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + +A+ VP DA GV +I R S +
Sbjct: 210 VSGAKVVATGSAITNYNFI-AHYGLPIKKKQFALICTVPMDAPGVKLIC-RTSYTQQAAV 267
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC- 298
G+ D +S ++ + VFD+V VP E VFM + + R + GC
Sbjct: 268 MGSPFDYPLSSRMDENDTIFVFDKVLVPWENVFMYGDVDKINAFFPQSGFLPRFTLQGCT 327
Query: 299 KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
++ V D + G A D G ++ ++ E+I ++ + + + G+
Sbjct: 328 RLAVKLDFIAGLLMKALDATGAGGFRGVQTRVGEVIGWRNLFWSLTESMVRD-PEPWVGD 386
Query: 358 YMIDLLLANVCKQNITRLPYEIAR--LAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
+I L + + + Y + + +D+A GL+ S DF+ P++ P + KY+ G
Sbjct: 387 TVIPKLEYGLTYRMFMQQGYPRIKEIIEQDVASGLIYLPSSSADFKSPDVRPYLDKYVRG 446
Query: 416 ATGKSTENRMRVLRLI 431
+ G + R+++++ +
Sbjct: 447 SEGMTAVERVKIMKAL 462
>gi|54024055|ref|YP_118297.1| putative 4-hydroxyphenylacetate 3-hydroxylase [Nocardia farcinica
IFM 10152]
gi|54015563|dbj|BAD56933.1| putative 4-hydroxyphenylacetate 3-hydroxylase [Nocardia farcinica
IFM 10152]
Length = 484
Score = 99.4 bits (246), Expect = 5e-19, Method: Composition-based stats.
Identities = 117/477 (24%), Positives = 210/477 (44%), Gaps = 49/477 (10%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T +Y+ SL + V GE++++ HP P ++A + LA + + M T
Sbjct: 1 MRTGAEYLSSLNDGRV-VLVDGEKVDDVTTHPAFAPVAQTIAELFDLAA--DPANGMQYT 57
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRC---VG--MDAFNA---IY 112
+ TG NR + +S E+L+ + + + Q T R VG + +F A ++
Sbjct: 58 APETGGPANRVFGIPRSQEELRARREAIQTWAQHTHGWVGRSPDHVGTFLASFAAHPEVF 117
Query: 113 STTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIV 172
+ A T +H+R + ++L V A+ P+ R + S L + +V
Sbjct: 118 AEGTRDFSANVTAFHRRLLA-------DNLYVSYAIIPPQVSRATTASGWEGEFLQVGVV 170
Query: 173 EVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQ 232
E+G++V G++ TGA + E L+ + D D+AVSF VP++AEG + +Y R+
Sbjct: 171 RETEEGLIVRGSQMLATGAAIADEILVSCIKPLGPDDQDFAVSFVVPANAEG-LKLYCRR 229
Query: 233 SCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHR 292
D L S + +ALVVFD V +P +RVF+ ++ AG R
Sbjct: 230 PY-APAATSSFDYPL-TSRYDEPDALVVFDDVLIPWDRVFVDRD----------IAGVRR 277
Query: 293 QSYGGCKVGVGD------------VLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLY 340
Q + +G+ + G A NGV K +++KL E+ L +
Sbjct: 278 QFFDTGAHALGNWQAQIRFATKLRFIAGVARRVTQVNGVDKIPSVQEKLGELAALVAGVE 337
Query: 341 ACGIACSSEGTQMKAGNYMID--LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ- 397
+ +A T +AG ++ L ++ Q + + + + D+ GG ++ +PS
Sbjct: 338 SAVLAAEYTATPDEAGQWVPGKRALYGSMGLQ--SEIYPRVLSILRDLVGGGVLQLPSSV 395
Query: 398 QDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
D P V Y+ + G +E+R+++ +L +I A ++ + AG+P
Sbjct: 396 ADLTSPLTSGDVTHYVQ-SPGVPSEDRIKLFKLAWDIIGSEFAGRHQQYELFYAGAP 451
>gi|126435227|ref|YP_001070918.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Mycobacterium sp. JLS]
gi|126235027|gb|ABN98427.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Mycobacterium sp. JLS]
Length = 501
Score = 99.4 bits (246), Expect = 5e-19, Method: Composition-based stats.
Identities = 113/439 (25%), Positives = 190/439 (43%), Gaps = 22/439 (5%)
Query: 3 TSEQYVESLRKLNLKVYFMGERI-ENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
T Q+++ + + + GE + EN +HP R + A + + Y+ +T TS
Sbjct: 5 TGAQFLDKINAMRPHIVIDGEVVSENVAEHPAFRDVARTYAKLFDMQHDPRYQDQLTFTS 64
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRC-----VGMDAFNAIYSTTY 116
TG VN + +S EDLK + + +T R + A A +
Sbjct: 65 PTTGDLVNASFLVPRSVEDLKRRRVAIQAWADETNGFLGRSGDYMSSSLTALGAAQTWFA 124
Query: 117 EMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
+ D G +R Y +Y ++NDL+ + P+ +R L+ S+Q L IVE R
Sbjct: 125 KADPKFG----ERIANYYEYARENDLLATHTLIPPQVNRSLTGSQQGGGQLAARIVEERP 180
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMR--EADADYAVSFAVPSDAEGVIMIYGRQSC 234
DGIVV GA+ T A + E L+ P+ +R DA Y+ +FA+ +DA G+ R C
Sbjct: 181 DGIVVRGARMLATVAPIADELLVFPSTVLRGTPEDAPYSYAFAIQNDAPGL-----RYLC 235
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMMVERFAG-YH 291
G+ D + + +A+VVFD VFVPN+RVFM + E AG
Sbjct: 236 RGSLHNGGSTFDEPLAARYEEMDAVVVFDDVFVPNDRVFMLGHPELCNAFYAETGAGALM 295
Query: 292 RQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
V + +G A+ G+ HI++ L E+I E A A ++G
Sbjct: 296 THQVVTRTVAKTEFFLGLASEIGAAIGIEGFQHIQEDLAELIVDLEIGRALLRAAEADGA 355
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKK 411
G Y+ N + ++ ++ + ++ +P + D + +++
Sbjct: 356 INDWGVYLPRWETLNAARNWYPKVSQRFPQIIRKFSASGLMALPGEADIA-SDARDDIEQ 414
Query: 412 YLAGATGKSTENRMRVLRL 430
YL GAT T+ R+++ +L
Sbjct: 415 YLQGATVNGTD-RVQLFKL 432
>gi|56962664|ref|YP_174390.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus clausii KSM-K16]
gi|56908902|dbj|BAD63429.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus clausii KSM-K16]
Length = 479
Score = 99.0 bits (245), Expect = 6e-19, Method: Composition-based stats.
Identities = 109/456 (23%), Positives = 195/456 (42%), Gaps = 47/456 (10%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIE-NPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
M+T Y++ + +L ++ GE ++ +HP + + + A Y + D + ++ A
Sbjct: 3 MVTGADYLKRIAQLESTIWIDGEFVKGKSTEHPAFKAVLEAKASLYDMVLDDAHADILQA 62
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVG-MDAFNAIYSTTYEM 118
+ K N + ++ DL + K +L Q T R ++ AI + +
Sbjct: 63 SD----KNANFSFEIPRTKADLTKRRKATQLWAQSTLGVLGRSPEYVNTMIAIMAGAKDF 118
Query: 119 DQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRG--LSPSEQADPDLYLHIVEVRE 176
G Y + + ND +P R E + + I+E E
Sbjct: 119 FAEDGKEYGESIQSIYERAVKNDYTFTHTFVNPSISRKPFYPDGESVEQPVAAKIIEENE 178
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMI----YGRQ 232
G+V+ GA+ T + E L++P+ A D+DY VPSD EG++ + +G++
Sbjct: 179 KGVVIDGARLLATQGGITDELLVLPSAAF--VDSDYLFGCTVPSDTEGLLFLSRPSFGKE 236
Query: 233 SCD----TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCK-----EYQFAGMM 283
+ + +EEG +A+VVFD VFVP ERVFM + FA
Sbjct: 237 TQFDYPLSATLEEG-------------DAVVVFDHVFVPWERVFMYRNEWLMSQLFARTG 283
Query: 284 VERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACG 343
+E F Y + K + L+G A D + + +H++ K+ E+I E + G
Sbjct: 284 IEAFLLYQAANRQIVKT---EWLLGVAQALVDTLNIGQHTHVQGKVSEVIVALEAMR--G 338
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDI---AGGLMVTMPSQQDF 400
S+E TQ +A Y I + K + ARL E I ++ PS++DF
Sbjct: 339 FVYSAE-TQAQANEYEIMVPKLEPLKASACYFQMTYARLIEIIQLLGASHFISAPSKKDF 397
Query: 401 RHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITL 436
P G + ++++ G S + + ++LRL ++++
Sbjct: 398 ASPIAGRL-ERFMRGEY-TSAKEKTKLLRLARDLSI 431
>gi|37524965|ref|NP_928309.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-HPA
3-monooxygenase large component) (4-HPA 3-hydroxylase)
[Photorhabdus luminescens subsp. laumondii TTO1]
gi|36784391|emb|CAE13270.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component (4-HPA
3-monooxygenase large component) (4-HPA 3-hydroxylase)
[Photorhabdus luminescens subsp. laumondii TTO1]
Length = 520
Score = 99.0 bits (245), Expect = 6e-19, Method: Composition-based stats.
Identities = 109/482 (22%), Positives = 207/482 (42%), Gaps = 25/482 (5%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y++SL+ ++Y GER+++ HP R S S+ Y L + + L T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNSAASIGQLYDALHAPETHDTLCWNTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F S +DL+ + ++T R A A
Sbjct: 74 TGSGGYTHKFFRFATSADDLRQQRDAIAEWSRQTYGWMGRTPDYKA---------AFGNA 124
Query: 122 LGT--TYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
LG Y+ +F + + K +Q+ + + A+ +P DR P +Q D+Y+ + +
Sbjct: 125 LGAFPEYYGQFADNARVWYKRIQETGVYFNHAIINPPIDRH-KPIDQTR-DVYIKLEKET 182
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSC 234
+ GI+VSGAK T + +H + I + + + D+A+ F P DAEG+ +I R S
Sbjct: 183 DAGIIVSGAKVVATNSALTHYNFIGFGSAQIMGDNPDFALMFVTPMDAEGMKLI-SRGSY 241
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
+ G+ D +S F ++A++V D+V +P E V + +++ + + +
Sbjct: 242 ELVAGVTGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRSRNWAVQAGFANLF 301
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
C ++ V D + + + GV + ++ L E++ ++ A +E
Sbjct: 302 PLQACVRLAVKLDFITALLQRSLECTGVIEFRGVQADLGEVVAWRNLFWSLSDAMWAEAK 361
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVK 410
K G YM D + +I + E ++ GL+ S +D +PEI +
Sbjct: 362 PWKGGAYMPDTQAIQTYRVMAPTAYTKIKNIIESNVTSGLIYLPSSVRDMNNPEIDKYLA 421
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGK 470
+Y+ G+ G R+++L+L+ + + ++ AGS R+ R G
Sbjct: 422 RYVRGSNGIDHVERIKILKLMWDAIGSEFGGRHELYEINYAGSQDEIRMQCLRHAHGSGN 481
Query: 471 KK 472
K
Sbjct: 482 MK 483
>gi|27479670|gb|AAO17197.1| HpaB [Photorhabdus luminescens]
Length = 520
Score = 98.6 bits (244), Expect = 8e-19, Method: Composition-based stats.
Identities = 111/482 (23%), Positives = 207/482 (42%), Gaps = 25/482 (5%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLM---TA 59
T E+Y++SL+ ++Y GER+++ HP R S S+ Y E ++ T
Sbjct: 15 TGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNSAASIGQLYDALHAPETHDVLCWNTD 73
Query: 60 TSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
T N G ++F S D+++ QR A ++ G + Y +
Sbjct: 74 TGN--GGYTHKFFRFATSA----DELRQQR---DAIAEWSRQTYGWMGRSPDYKAAFGNV 124
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
Y+ +F + + K +Q+ + + A+ +P DR P+++ D+Y+ + +
Sbjct: 125 LGAFPEYYGQFADNARTWYKRIQETGVYFNHAIVNPPIDRH-KPADETR-DVYIKLEKET 182
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSC 234
+ GI+VSGAK T + +H + I A D D+A+ F P DAEGV +I R S
Sbjct: 183 DAGIIVSGAKVVATNSALTHYNFIGFGSAQVMGDNPDFALMFVAPMDAEGVKLI-SRGSY 241
Query: 235 DTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ 293
+ G+ D +S F ++A++V D+V +P E V + +++ A +
Sbjct: 242 ELVAGATGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRARNWAIQAGFTSLF 301
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
C ++ V D + + + GV + ++ L E++ ++ A +E
Sbjct: 302 PLQACIRLAVKLDFITALLQRSLECTGVIEFRGVQANLGEVVAWRNLFWSLSDAMWAEAK 361
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVK 410
K+G YM D + +I + E ++ GL+ S +D +PEI +
Sbjct: 362 PWKSGAYMPDTQAIQTYRVMAPMAYTKIKNIIESNVTSGLIYLPSSVRDMNNPEIDKYLA 421
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGK 470
+Y+ G+ G R+++L+L+ + + ++ AGS R+ R G
Sbjct: 422 RYVRGSNGIDHVERIKILKLMWDAIGSEFGGRHELYEINYAGSQDEIRMQCLRHAHGSGN 481
Query: 471 KK 472
K
Sbjct: 482 MK 483
>gi|146304539|ref|YP_001191855.1| 4-hydroxyphenylacetate 3-hydroxylase [Metallosphaera sedula DSM
5348]
gi|145702789|gb|ABP95931.1| 4-hydroxyphenylacetate 3-hydroxylase [Metallosphaera sedula DSM
5348]
Length = 493
Score = 98.2 bits (243), Expect = 1e-18, Method: Composition-based stats.
Identities = 112/461 (24%), Positives = 197/461 (42%), Gaps = 44/461 (9%)
Query: 17 KVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTGKQVNRFCHLHQ 76
++Y+ GE++ + +HP R ++++V+ Y L DEYK + + G++ + +
Sbjct: 19 EIYYNGEKVSDVTEHPAFRAAIHTVSDYYDLHWKDEYKEYLRVYNPDVGEETSITFFRPR 78
Query: 77 STEDLKDKVKMQRL-MGQKTASCFQRCVGMDAFNAIYSTTYEM----------DQALGTT 125
+ E+L+ RL MG F R G + Y + M + G
Sbjct: 79 NKEELR------RLRMGISKIYDFYR--GFFGRSPDYLNVWTMLFYAHADDYFGKVFGNK 130
Query: 126 YHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAK 185
+ IE + DL A+ P DR PS+ DP + + +V +G+VV GA
Sbjct: 131 MMENVIEIYREAAKQDLFYTHAIVAPMYDRSRPPSQWEDPYIQVGVVRETTEGLVVRGAA 190
Query: 186 AHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADI 245
T S +P I R+ D Y+V F++P++++GV I R EE +
Sbjct: 191 LLSTAGPYSERLWYLPNIK-RDTDPRYSVFFSLPTESKGVKFISRR---GFHPKEEFGEF 246
Query: 246 DLG-NSEFGGHEALVVFDRVFVPNERV-FMCKEYQFAGMM-----VERFAGYHR--QSYG 296
+ S + +A++V D V +P +RV F K + G M + + +H Q Y
Sbjct: 247 EYPITSRYEEPDAIMVLDNVLIPWDRVIFYKKPEEIEGFMWHTVNLRGWFNWHFVIQHYS 306
Query: 297 GCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIE-MIHLNETLYACGIACSSEGTQMKA 355
K L G A A+ G+ ++++KL E +I+L +Y G+ S E +
Sbjct: 307 RTK-----FLAGLAIAIAEAVGINNFINVQEKLGEILIYL--AMYEAGMVASEELGEQLP 359
Query: 356 GNYMIDLLLA-NVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKKYL 413
G Y + +A + LP I + I+ G + +P+ +DF +PE ++ KYL
Sbjct: 360 GVYRPNPQIAIATSSMGMKALP-RINEILRSISAGSSIPVPAGIRDFENPEERALLDKYL 418
Query: 414 AGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
A + G R+++ ++ + + Y G P
Sbjct: 419 A-SKGLPALERVKLFNILWDTIGSETGMRYEQYDRFSRGDP 458
>gi|19570941|dbj|BAB86378.1| 4-nitrophenol hydroxylase component A [Rhodococcus sp. PN1]
Length = 517
Score = 97.8 bits (242), Expect = 2e-18, Method: Composition-based stats.
Identities = 99/423 (23%), Positives = 181/423 (42%), Gaps = 22/423 (5%)
Query: 17 KVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTGKQVNRFCHLHQ 76
+VYF GER+++ HP R S SVA Y + AT G + F +
Sbjct: 34 EVYFRGERVDDVTTHPAFRNSARSVARMYDALHQPDGGRAGGATDTGNGGFTHPFFKTAR 93
Query: 77 STEDLKDKVKMQRLMGQKTASCFQRCV-----GMDAFNAIYSTTYEMDQALGTTYHKRFI 131
S DL ++ + +QR V + A + T + Y +
Sbjct: 94 SANDL--------VLSRDAIVAWQREVYGWLGRSPDYKASFLGTLGANADFYGPYRDNAL 145
Query: 132 EYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAKAHQTGA 191
+ K+ Q+ L ++ A+ +P DR E A D+ +H+VE + G++VSGAK TG+
Sbjct: 146 RWYKHAQERMLYLNHAIVNPPIDRDKPADETA--DVCVHVVEETDAGLIVSGAKVVATGS 203
Query: 192 VNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADIDLG-NS 250
++ + I +R+ +Y + F VP D+ G + ++ R S + G D +S
Sbjct: 204 AITNANFIAHYGLLRK--KEYGLIFTVPMDSPG-LKLFCRTSYEMNAAVMGTPFDYPLSS 260
Query: 251 EFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC-KVGVG-DVLIG 308
F ++A++VFDRV VP E VF + A V + R + GC ++ V D + G
Sbjct: 261 RFDENDAIMVFDRVLVPWENVF-AYDTDTANGFVMKSGFLSRFMFHGCARLAVKLDFIAG 319
Query: 309 AAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLLANVC 368
+ G ++ + + E+++ + + A + Q G +L
Sbjct: 320 CVMKGVEMTGSRDSAVCRCRSGEILNWRDMFWGLSDAMAKSPEQWVNGAVQPNLNYGLAY 379
Query: 369 KQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENRMRVL 428
+ + +P GL+ D+ +P + P + +Y+ G+ G + +R+++L
Sbjct: 380 RTFMGVVPAGQGDHPAGAGSGLIYLNSHASDWANPAMRPYLDQYVRGSNGVAPIDRVQLL 439
Query: 429 RLI 431
+L+
Sbjct: 440 KLL 442
>gi|118069797|ref|ZP_01538038.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit [Serratia
proteamaculans 568]
gi|118015989|gb|EAV29920.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit [Serratia
proteamaculans 568]
Length = 520
Score = 96.3 bits (238), Expect = 4e-18, Method: Composition-based stats.
Identities = 110/499 (22%), Positives = 213/499 (42%), Gaps = 37/499 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T ++Y++SL+ ++Y GER+++ HP R + SV Y L + L T
Sbjct: 15 TGDEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVGQLYDALHDPVSQDRLCWGTD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
+G ++F +S D+++ QR A ++ G Y +
Sbjct: 74 TGSGGYTHKFFRYARS----PDELRQQR---DAIADWSRQSYGWMGRTPDYKAAFGSALG 126
Query: 122 LGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRED 177
++ +F + + K +Q+ L + A+ +P DR +E D +++ + + +
Sbjct: 127 ANPEFYGQFADNARHWYKRIQETGLYFNHAIVNPPIDRHKPVNEVKD--VFIQVEKETDA 184
Query: 178 GIVVSGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCDT 236
GI+VSGAK T + +H + I A D D+A+ F P DAEGV +I R S +
Sbjct: 185 GIIVSGAKVVATNSALTHYNFIGFGSAQVMGDNPDFALMFVAPMDAEGVKLI-SRASYEL 243
Query: 237 RKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAG 289
G+ D +S F ++A+++ D V +P E V + C+ + G F
Sbjct: 244 VAGATGSPFDYPLSSRFDENDAILIMDHVLIPWENVLIYRDFDRCRRWSTEGGFARLFP- 302
Query: 290 YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSE 349
Q+ V + D + + GV + ++ L E++ ++ A +E
Sbjct: 303 --LQACVRLAVKM-DFITALLQKSLACTGVLEFRGVQADLGEVVAWRNLFWSLTDAMCAE 359
Query: 350 GTQMKAGNYMIDLLLANVCKQNITRLPYEIAR----LAEDIAGGLMVTMPSQQDFRHPEI 405
T+ + G Y+ D + + P A+ + +++ GL+ S +D +PEI
Sbjct: 360 ATKWENGAYLPD---SAALQTYRVMAPMAYAKVKNIIEKNVTSGLIYLPSSVRDMNNPEI 416
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQG 465
+ +Y+ G+ G R+++L+L+ + + ++ AGS R+ RQ
Sbjct: 417 DKYLSRYVRGSNGMDHVERIKILKLMWDAIGSEFGGRHELYEINYAGSQDEIRLQCLRQA 476
Query: 466 DLEGKKKLARAIAHIDESL 484
+G + + + +D+ L
Sbjct: 477 --QGSGTMGKMMEMVDKCL 493
>gi|154246515|ref|YP_001417473.1| 4-hydroxyphenylacetate 3-hydroxylase [Xanthobacter autotrophicus
Py2]
gi|154160600|gb|ABS67816.1| 4-hydroxyphenylacetate 3-hydroxylase [Xanthobacter autotrophicus
Py2]
Length = 484
Score = 96.3 bits (238), Expect = 4e-18, Method: Composition-based stats.
Identities = 125/496 (25%), Positives = 212/496 (42%), Gaps = 34/496 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T Y + LR +++ GER+++ H +P ++ A Y L + +T +
Sbjct: 4 TGAAYKDGLRD-GREIWIDGERVKDVTTHAAFKPIVDIKARMYDLHHEEATAPALTYVED 62
Query: 63 LTGKQVNRFCHLHQSTED-LKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTT--YEMD 119
V+ H +T+D K + ++ + R VG + ++S +M
Sbjct: 63 ---NAVHSIFHQPPTTQDHWHAKRQGVDILLKDVGGVVTR-VGDETIGEMWSLQDGRDML 118
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
A+ + ++K V + D A TDPKGDR SE+ DPD+ +H+ + + GI
Sbjct: 119 AAIDPRFAANIDNHIKRVVEEDPFHVSANTDPKGDRSRHISER-DPDMMVHVTKETDAGI 177
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIA--MREADADYAVSFAVPSDAEGVIMIYGRQSCDTR 237
++ GAK ++T A + + + PT+ E ++DYA+ V A GV I R R
Sbjct: 178 IIRGAK-YETAAAYADQAYLKPTVGAWTDEKESDYALGCIVKMGAPGVKHIC-RSGFAGR 235
Query: 238 KMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFM---CKEYQFAGMMVERFAGYHRQS 294
AD L N + + LV+FD V +P E VF K QF + R++ Y
Sbjct: 236 T--NPADYPLAN-RYDEVDTLVIFDDVLIPWEDVFFYRYTKAAQFVRGTLHRYSAY---P 289
Query: 295 YGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMK 354
Y + V D++IGAA A G+ K +++KL ++ E + A A + +
Sbjct: 290 YVLRLLYVADMMIGAALWNAKQTGLDKLQSVQEKLADLAVYREGINAHLTASIALAEKSP 349
Query: 355 AGNYMID--LLLAN---VCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIV 409
AG M + +L A C Q LP + E I G + VT P+ F +
Sbjct: 350 AGLLMPNQSILYAGRVLACSQ----LPAMMHATRELIGGQICVT-PNVAAFEAEGTSDWL 404
Query: 410 KKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRI-MIARQGDLE 468
KK+ +E+R ++L ++ A G+R + A +P + + + D E
Sbjct: 405 KKFYTLNDNWESEDRRKLLAFARDLVSSDYA-GHRLAFVQFAQAPHFNHLAAVYKSFDFE 463
Query: 469 GKKKLARAIAHIDESL 484
G R A + + +
Sbjct: 464 GPLDFVRKTAGLSDKV 479
>gi|70730720|ref|YP_260461.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Pseudomonas fluorescens Pf-5]
gi|68345019|gb|AAY92625.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Pseudomonas fluorescens Pf-5]
Length = 520
Score = 95.1 bits (235), Expect = 9e-18, Method: Composition-based stats.
Identities = 108/483 (22%), Positives = 212/483 (43%), Gaps = 25/483 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTAT 60
+T +Y+ SLR + ++Y G+R+++ HP R S S+A Y L + + L T
Sbjct: 14 LTGAEYLASLRD-DREIYIYGDRVKDVTTHPAFRNSAASMARLYDALHDPATKEQLCWDT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G +RF +S D+++ QR A + G + Y +
Sbjct: 73 DTGNGGYTHRFFRSAKS----PDELRQQR---DAIADWSRLTYGWMGRSPDYKAAFGSAL 125
Query: 121 ALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVRE 176
++ RF + + K +Q+ L ++ A+ +P DR P +Q D+++ + E E
Sbjct: 126 GANPEFYGRFADNARTWYKRIQEACLYLNHAIVNPPIDRD-KPVDQVK-DVFISVDEEVE 183
Query: 177 DGIVVSGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCD 235
GI+VSGAK T + +H + + A D D+A+ F P + G+ +I R S +
Sbjct: 184 GGIIVSGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTRGMKLIC-RPSYE 242
Query: 236 TRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ- 293
+ G+ D +S F ++A+++ D+VF+P E V + ++++ + G+ R
Sbjct: 243 LQAGMTGSPFDYPLSSRFDENDAILIMDKVFIPWENVLIYRDFERCRQWFPQ-GGFGRLF 301
Query: 294 SYGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
GC ++ V D + G A G + ++ ++ E++ ++ A +
Sbjct: 302 PMQGCTRLAVKLDFITGLLVKALKCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMHGNAS 361
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPS-QQDFRHPEIGPIVK 410
+ G Y+ + + +I ++ E + ++ +PS +D + P + +
Sbjct: 362 EWMNGVYLPSTQALQAYRVLAPQAYTDIKKIIEQVVASGLIYLPSGSRDLKDPVLNQYLG 421
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVG-YRTESMHGAGSPQAQRIMIARQGDLEG 469
Y G+ G E R+++L+L+ + +GT G + ++ AGS R+ R G
Sbjct: 422 TYCRGSGGMGHEERIKILKLLWD-AIGTEFGGRHELYEINYAGSQDEIRMQCLRHAQASG 480
Query: 470 KKK 472
K
Sbjct: 481 SMK 483
>gi|54026336|ref|YP_120578.1| putative phenol hydroxylase large subunit [Nocardia farcinica IFM
10152]
gi|54017844|dbj|BAD59214.1| putative phenol hydroxylase large subunit [Nocardia farcinica IFM
10152]
Length = 539
Score = 95.1 bits (235), Expect = 1e-17, Method: Composition-based stats.
Identities = 103/436 (23%), Positives = 186/436 (42%), Gaps = 15/436 (3%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
MT +Y+ESLR +++ GER+ + HP R + A Y + ++TA T
Sbjct: 37 MTGAEYIESLRD-GREIWLHGERVADVTTHPAFRNPIRMTARLYDSLHSGPHTDVVTAPT 95
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G F S DL + + T R + A + T ++
Sbjct: 96 DTGNGGVTMPFFKTPTSAADLVRERDAIAAWARMTYGWMGRS---PDYKASFLGTLHANK 152
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 153 ELYAPFQDNAERWYRESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDAGLI 210
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + ++A+ VP DA GV +I R S
Sbjct: 211 VSGAKVVATGSAITNYNFI-AHYGLPIKKKEFALICTVPMDAPGVKLIC-RSSYTQHAAV 268
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC- 298
G+ D +S ++ + VFD+V VP E VFM + + R ++ GC
Sbjct: 269 MGSPFDYPLSSRMDENDTIFVFDKVLVPWENVFMYGDVDKINAFFPQSGFLPRFTFQGCT 328
Query: 299 KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
++ V D + G A D G ++ ++ E+I + A ++ + G+
Sbjct: 329 RLAVKLDFIAGLLLKALDATGAGGFRGVQTRVGEVIGWRNLFWTLTDAMANN-PEPWIGD 387
Query: 358 YMIDLLLANVCKQN--ITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
+I L + + I P + +D+A GL+ S DF+ PE+ P + KY+ G
Sbjct: 388 TVIPRLEYGLTYRMFMIQGYPRIKEIIEQDVASGLIYLPSSAADFKSPEVRPYLDKYVRG 447
Query: 416 ATGKSTENRMRVLRLI 431
+ G + +R++V++ +
Sbjct: 448 SDGITAVDRVKVMKAL 463
>gi|70608003|ref|YP_256873.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Sulfolobus acidocaldarius DSM 639]
gi|68568651|gb|AAY81580.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Sulfolobus acidocaldarius DSM 639]
Length = 490
Score = 94.4 bits (233), Expect = 2e-17, Method: Composition-based stats.
Identities = 112/467 (23%), Positives = 210/467 (44%), Gaps = 34/467 (7%)
Query: 5 EQYVESLRKLNL-KVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNL 63
E+Y++SL++ N +VY+ GE++E+ V+H + + +VA Y L DE + +
Sbjct: 6 EEYIKSLKEGNHGEVYYNGEKVEDIVNHHAFKIPIKTVAKYYDLHWEDE---ALRVYNRD 62
Query: 64 TGKQVNRFCHLHQSTEDLKD-KVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYE--MDQ 120
G+ + +S EDLK +V + R+ + ++ ++ ++ E +
Sbjct: 63 VGEDTSISFFRPRSKEDLKKMRVGLNRIYDNYYGFFGRSPDYLNIWSMVFYAHAEDYFGK 122
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
G+ + I K DL A+ P DR PS+ DP + + +V+ +G++
Sbjct: 123 VFGSKIMENVINIYKEATKKDLFYTHAIVAPMYDRSRPPSQWEDPYIQIGVVKETNEGVI 182
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
V GA T + +P I R++D YA+ F++P +++GV I R +
Sbjct: 183 VRGAAMICTAGPYAEMLWYLPNI-RRDSDPRYAIFFSIPGNSKGVKFITRRGFYPRENLG 241
Query: 241 EGADIDLGNSEFGGHEALVVFDRVFVPNER-VFMCKEYQFAGMM-----VERFAGYHR-- 292
E + + +S F +A++V D V +P +R +F K + G M + + +H
Sbjct: 242 E-FEYPI-SSRFEESDAILVLDNVLIPWDRIIFYKKPEEIEGFMWHTVQLRTWFNWHFAI 299
Query: 293 QSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIE-MIHLNETLYACGIACSSEGT 351
Q Y K G A A+ G+ ++++KL E +I+L TL + + E
Sbjct: 300 QHYSRLK-----FYAGLAMAIAESVGINNFINVQEKLGEILIYL--TLNEAALIAAEENG 352
Query: 352 QMKAGNYMIDLLLANVCKQ-NITRLPY--EIARLAEDIAGGLMVTMPSQ-QDFRHPEIGP 407
+ Y + ++ N+ LP EI RL I+ G + +P+ +DF +PE
Sbjct: 353 EYLPNIYRPNPYISITASHFNMRALPRVDEILRL---ISAGSSIPIPAGIRDFENPEERA 409
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
+++KYLA + G R+++ L+ ++ + + Y G P
Sbjct: 410 MLEKYLA-SKGLPALERVKLFNLLWDVIGSESGMRYEQYDRFSRGDP 455
>gi|21954030|gb|AAC23548.2| chlorophenol-4-monooxygenase component 2 [Burkholderia cepacia]
Length = 515
Score = 94.0 bits (232), Expect = 2e-17, Method: Composition-based stats.
Identities = 116/460 (25%), Positives = 201/460 (43%), Gaps = 52/460 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T +QY+ESL + V+ E+I+N HP+ R VA Y L + + ++T
Sbjct: 1 MRTGKQYLESLNDGRV-VWVGNEKIDNVATHPLTRDYAERVAQFYDLHHRPDLQDVLTFV 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKM-QRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD 119
+ G + +R + L+ K K + ++ + A + R DA N + TTY D
Sbjct: 60 -DADGVRRSRQWQDPKDAAGLRVKRKYHETILREIAAGSYGRLP--DAHNYTF-TTYADD 115
Query: 120 Q---------ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
A G + ++K +++ DL DP+ DR ++ P+L
Sbjct: 116 PEVWEKQSIGAEGRNLTQNIHNFLKLLREKDLNCPLNFVDPQTDRSSDAAQARSPNL--R 173
Query: 171 IVEVREDGIVVSGAKAHQTG-AVNSHEH---LIMPTIAMREADADYAVSFAVPSDAEGVI 226
IVE +DGI+V+G KA TG A + H L P I + + A+P++ GV
Sbjct: 174 IVEKTDDGIIVNGVKAVGTGIAFGDYMHIGCLYRPGIP-----GEQVIFAAIPTNTPGV- 227
Query: 227 MIYGRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
++ R+S E G+ ++ VFD VF+P E+VF + A + +R
Sbjct: 228 TVFCRESTVKNDPAEHPLASQGDE----LDSTTVFDNVFIPWEQVFHIGNPEHAKLYPQR 283
Query: 287 ---FAGYH---RQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLY 340
+ YH RQ V ++++G A L ++ G K + ++ +++ + +
Sbjct: 284 IFDWVHYHILIRQ------VLRAELIVGLAILITEHIGTSKLPTVSARVAKLVAFHLAMQ 337
Query: 341 ACGIACSSEGTQMKAGNYMIDLLLANVCK----QNITRLPYEIARLAEDIAGGLMVTMPS 396
A IA G K G Y + L+ + + QN + YE+ D+AG + +PS
Sbjct: 338 AHLIASEETGFHTKGGRYKPNPLIYDFGRAHFLQNQMSVMYELL----DLAGRSSLMIPS 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITL 436
+ + + G K G G E R+++ R+I ++ L
Sbjct: 394 EGQWDDSQSGQWFVKLNNGPKGNPRE-RVQIGRVIRDLYL 432
>gi|37524265|ref|NP_927609.1| hypothetical protein plu0246 [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36783688|emb|CAE12541.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii
TTO1]
Length = 517
Score = 93.6 bits (231), Expect = 3e-17, Method: Composition-based stats.
Identities = 104/458 (22%), Positives = 206/458 (44%), Gaps = 38/458 (8%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKH-LMTAT 60
+T ++++ L +V+ GERI + V+HP + ++A Y Y+ L TAT
Sbjct: 21 LTGTEFLDGLND-GREVWAYGERIHDVVNHPAFQNPARAIAKLYDALHDPAYRDVLTTAT 79
Query: 61 SNLTGKQVNRFCHLHQSTEDL---KDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYE 117
+ + F + +S +DL +D + A+ + G + Y ++
Sbjct: 80 DTGSCGVTHPFFRIPRSQQDLIADRDAI----------AAWARMSYGWLGRSPDYKASFL 129
Query: 118 MDQALGTTYHKRFIEYMK--YVQDNDLVV--DGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ + F + K Y++ + V + ++ +P DR LSP E D + +H+ +
Sbjct: 130 TSLGVKPEIYGDFADNAKSWYIRSQESVFYWNHSIINPPIDRHLSPDEIGD--ICIHVEK 187
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLI----MPTIAMREADADYAVSFAVPSDAEGVIMIY 229
+DG++VSGAK TG+ SH + I +P I RE +A+ F +P + GV +I
Sbjct: 188 ECDDGLIVSGAKVVATGSAISHYNFIGHYGLP-IKKRE----FALVFTLPMNTPGVKLIC 242
Query: 230 GRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFA 288
R S + G+ D +S F ++ +++ D+V VP E +F+ + +
Sbjct: 243 -RPSYAMAADKMGSPFDYPLSSRFDENDTIMILDKVKVPWENIFIYGDVDKVSLFFAESG 301
Query: 289 GYHRQS-YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIAC 346
+HR +G ++ V D L G + G ++ ++ E++ +A A
Sbjct: 302 YFHRAMLHGVTRLAVKLDFLSGLLIKGVEATGTKDFRGVQARVGEVLSWRNMFWALSDAM 361
Query: 347 SSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIAR--LAEDIAGGLMVTMPSQQDFRHPE 404
+ + +G+ ++ + + L Y + + +D+ L+ +DF +PE
Sbjct: 362 I-KSPEPWSGDALLPRYEYGIAYRWFMTLGYPRVKEIIEQDLGSALIYINSHARDFSNPE 420
Query: 405 IGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG 442
+ P + KY+ G+ G S R+++++LI + ++GT G
Sbjct: 421 LSPYLDKYMRGSNGYSAVERVKLMKLIWD-SIGTEFAG 457
>gi|111024862|ref|YP_707282.1| phenyl hydroxylase, oxygenase component [Rhodococcus sp. RHA1]
gi|110823841|gb|ABG99124.1| phenyl hydroxylase, oxygenase component [Rhodococcus sp. RHA1]
Length = 539
Score = 93.2 bits (230), Expect = 4e-17, Method: Composition-based stats.
Identities = 101/436 (23%), Positives = 192/436 (44%), Gaps = 15/436 (3%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATS 61
MT ++Y+ES+ + +++ GER+++ +HP R S+ +A Y E+ +T +
Sbjct: 37 MTGDEYIESISD-DREIWLHGERVKDHTNHPAFRNSVRMIARLYDSLHTGEHVDTLTTGT 95
Query: 62 NLTGKQVNR-FCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+ V F ++TED+ + T R + A + T ++
Sbjct: 96 DTGNGGVTMPFFRTAKTTEDVLADRDAIATWARMTYGWMGRS---PDYKASFLGTLHANK 152
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + + Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 153 ELYSPFEANAERWYRESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDSGLI 210
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + ++A+ VP A GV +I R S
Sbjct: 211 VSGAKVVATGSAITNYNFI-AHYGLPIKKKEFALICTVPMGAPGVKLI-SRASYAQNAAI 268
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC- 298
G D +S F ++A++VFD+V VP E VFM + R GC
Sbjct: 269 TGTPFDYPLSSRFDENDAILVFDKVLVPWENVFMYGAVDKINTFFPQSGFLPRAMLQGCT 328
Query: 299 KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGN 357
++ V D + G A D G ++ ++ E+I ++ + + + Q G+
Sbjct: 329 RLAVKLDFIAGLLMKALDCTGAGGFRGVQTRVGEVIGWRNLFWSLTESMARDPEQW-IGD 387
Query: 358 YMIDLLLANVCKQNITRLPYEIAR--LAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAG 415
+I L + + Y + + +D+A GL+ S DF+ EI P + KY+ G
Sbjct: 388 TVIPKLEYGLTYRMFMMQGYPRIKEIIEQDVASGLIYLPSSASDFKSTEIRPYLDKYVRG 447
Query: 416 ATGKSTENRMRVLRLI 431
+ G + +R++V++ +
Sbjct: 448 SDGITAVDRVKVMKAL 463
>gi|5833403|gb|AAD53503.1|AF144422_10 HpaB [Salmonella enterica subsp. enterica serovar Dublin]
Length = 520
Score = 92.8 bits (229), Expect = 4e-17, Method: Composition-based stats.
Identities = 108/496 (21%), Positives = 211/496 (42%), Gaps = 25/496 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTAT 60
+T E+Y++SL+ ++Y GER+++ HP R + SVA Y L + L T
Sbjct: 14 LTGEEYLKSLQD-GREIYIYGERVKDVTTHPAFRNAAASVAQLYDALHKPSMQDTLCWNT 72
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
+G ++F + +S DL+ + + + S R + A + +
Sbjct: 73 DTGSGGYSDKFIRVAKSAYDLRQQRDAIAEWSRLSYSWMGR---TPDYKAAFGCALGANP 129
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
+ + + +Q+ L + A+ +P DR P+++ D+Y+ + + + I+
Sbjct: 130 TFYGQFEQNARNWYTRIQETGLYFNHAIVNPPIDRH-KPADEMK-DVYIKLEKETDARII 187
Query: 181 VSGAKAHQTGAVNSHEHLIM--PTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
V G K T + +H ++I AM E + D+A+ F P DAEGV +I R S +
Sbjct: 188 VCGGKVVSTNSALTHYNMIGFGAAHAMGE-NPDFALMFVAPMDAEGVKLI-SRASYEMVA 245
Query: 239 MEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYH 291
G+ D +S F ++A++V D+V +P E V + C+ + G Y
Sbjct: 246 GATGSPFDYPLSSRFDENDAILVMDKVLIPWENVLIYRDFDRCRRWTMEGGFARM---YP 302
Query: 292 RQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGT 351
Q+ V + D + + + G + ++ L E++ +A + SE T
Sbjct: 303 LQACVRLAVKL-DFITALLKKSLECTGTVEFRGVQADLGEVVAWRNMFWALSDSMCSEAT 361
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVK 410
G ++ D + +I + E ++ GL+ S +D +P+I +
Sbjct: 362 PWVNGAWLPDHAALQTYRVMAPMAYAKIKNIIERNVTSGLIDLPSSARDLNNPQIDQYLA 421
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGK 470
KY+ G+ G R+++L+L+ + + ++ +GS R+ RQ G
Sbjct: 422 KYVRGSNGMDHVERIKILKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG- 480
Query: 471 KKLARAIAHIDESLDK 486
+ + +A +D L +
Sbjct: 481 -NMDKMMAMVDRCLSE 495
>gi|84325223|ref|ZP_00973263.1| COG2368: Aromatic ring hydroxylase [Pseudomonas aeruginosa 2192]
gi|126196150|gb|EAZ60213.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa 2192]
Length = 520
Score = 92.4 bits (228), Expect = 6e-17, Method: Composition-based stats.
Identities = 103/477 (21%), Positives = 206/477 (43%), Gaps = 15/477 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y+ SLR + ++Y G+R+++ HP R + S+A Y L + + L T
Sbjct: 15 TGEEYLASLRD-DREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F +S ++L+ + + T R + A + + +
Sbjct: 74 TGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGR---TPDYKAAFGSALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + K +Q+ L ++ A+ +P DR P +Q D+++ + E + GIVV
Sbjct: 131 FYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRD-KPVDQVK-DVFISVDEEVDGGIVV 188
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H + + A D D+A+ F P + G+ +I R S +
Sbjct: 189 SGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLIC-RPSYELVAGI 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ-SYGGC 298
G+ D +S F ++A++V D+VF+P E V + ++++ + G+ R GC
Sbjct: 248 AGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQ-GGFGRLFPMQGC 306
Query: 299 -KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
++ V D + GA A G + ++ +L E++ ++ A ++ +G
Sbjct: 307 TRLAVKLDFITGALYKALQCTGSLEFRGVQAQLGEVVAWRNLFWSLTDAMYGNASEWHSG 366
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKKYLAG 415
++ + + EI + E + ++ +PS +D +P++ + Y G
Sbjct: 367 AFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRG 426
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G R+++L+L+ + + ++ AGS R+ RQ G K
Sbjct: 427 SGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAIGSGAMK 483
>gi|67511478|emb|CAJ01325.1| putative phenol hydroxylase large subunit A1 [Rhodococcus
erythropolis]
Length = 542
Score = 91.7 bits (226), Expect = 1e-16, Method: Composition-based stats.
Identities = 102/448 (22%), Positives = 193/448 (43%), Gaps = 26/448 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
MT ++Y+ SL+ +++ G+R+++ HP R + A Y E+ +T T
Sbjct: 40 MTGDEYISSLQD-GREIWLHGDRVKDVTTHPAFRNPIRMTARLYDALHTGEHVDALTVPT 98
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G F S+ DL + + T R + A + T ++
Sbjct: 99 DTGNGGVTMPFFRTPTSSADLLKERDAIATWARMTYGWMGRS---PDYKASFLGTLHANK 155
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 156 ELYAPFQDNAERWYRESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDAGLI 213
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + +A+ VP DA GV +I C T E
Sbjct: 214 VSGAKVVATGSAITNYNFI-AHYGLPIKKKQFALICTVPMDAPGVKLI-----CRTSYTE 267
Query: 241 EGA------DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQS 294
A D L +S ++ + VFD+V VP E VFM + + R +
Sbjct: 268 HAAVMGSPFDYPL-SSRMDENDTIFVFDKVLVPWENVFMYGDVDRINAFFPQSGFLPRFT 326
Query: 295 YGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
+ GC ++ V D + G A + G ++ ++ E+I ++ + + + Q
Sbjct: 327 FQGCTRLAVKLDFIAGLLMKALEATGAGGFRGVQTRVGEVIGWRNLFWSLTESMARDPEQ 386
Query: 353 MKAGNYMIDLLLANVCKQN--ITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
G+ +I L + + I P + +D+A GL+ S DF+ P++ P +
Sbjct: 387 W-VGDSVIPKLEYGLTYRMFMIQGYPRIKEIIEQDVASGLIYLPSSSLDFKSPDVRPYLD 445
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGT 438
KY+ G+ G + +R++V++ + + ++GT
Sbjct: 446 KYVRGSDGITAVDRVKVMKALWD-SIGT 472
>gi|53715965|ref|YP_106450.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei ATCC 23344]
gi|67642551|ref|ZP_00441306.1| COG2368: Aromatic ring hydroxylase [Burkholderia mallei GB8 horse
4]
gi|83620851|ref|ZP_00931266.1| COG2368: Aromatic ring hydroxylase [Burkholderia mallei FMH]
gi|83623971|ref|ZP_00934228.1| COG2368: Aromatic ring hydroxylase [Burkholderia mallei JHU]
gi|100267261|ref|ZP_01341524.1| hypothetical protein Bmal2_03000671 [Burkholderia mallei
2002721280]
gi|100915808|ref|ZP_01344295.1| hypothetical protein Bmal10_03002870 [Burkholderia mallei 10399]
gi|121597015|ref|YP_990536.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei SAVP1]
gi|124381535|ref|YP_001025025.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei NCTC 10229]
gi|126445883|ref|YP_001079370.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei NCTC 10247]
gi|52421935|gb|AAU45505.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei ATCC 23344]
gi|121224813|gb|ABM48344.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei SAVP1]
gi|124289555|gb|ABM98824.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei NCTC 10229]
gi|126238737|gb|ABO01849.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
mallei NCTC 10247]
gi|147745695|gb|EDK52774.1| chromophore biosynthetic protein PvcC [Burkholderia mallei FMH]
gi|147754920|gb|EDK61984.1| chromophore biosynthetic protein PvcC [Burkholderia mallei JHU]
gi|148025123|gb|EDK83292.1| chromophore biosynthetic protein PvcC [Burkholderia mallei
2002721280]
Length = 494
Score = 91.3 bits (225), Expect = 1e-16, Method: Composition-based stats.
Identities = 118/503 (23%), Positives = 208/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRERLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 112 LEAGADYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 170 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E+I L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELISLQH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L G + AR
Sbjct: 453 IRLDSLTWATRSGQLAGCEAFAR 475
>gi|15898843|ref|NP_343448.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA) [Sulfolobus
solfataricus P2]
gi|13815338|gb|AAK42238.1| 4-hydroxyphenylacetate-3-hydroxylase (hpaA) [Sulfolobus
solfataricus P2]
Length = 508
Score = 90.9 bits (224), Expect = 2e-16, Method: Composition-based stats.
Identities = 101/464 (21%), Positives = 207/464 (44%), Gaps = 31/464 (6%)
Query: 7 YVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSNLTGK 66
Y++S+++ VY+ GE +++ +H + +++VA Y L ++YK + + G+
Sbjct: 25 YIKSIKENPPVVYYEGEVVKDVTEHSAFKIPISTVAKYYDLHWDEKYKEYLRVYNLDVGE 84
Query: 67 QVNRFCHLHQSTEDL-KDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYE--MDQALG 123
+ + ++ +DL K + + ++ + ++ + ++ E + G
Sbjct: 85 ETSISFLRPKNKKDLGKLRDGLVKIYDYYRGFFGRSPDYLNLWTMVFYAHAEDYFGKQFG 144
Query: 124 TTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSG 183
+ + + IE K DL A+ P DR PS+ DP + + IVE + +G+VV G
Sbjct: 145 SKFMENAIEIYKEATKRDLFYTHAIVAPMYDRSRPPSQWEDPYIQVGIVEEKPEGVVVRG 204
Query: 184 AKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGA 243
A T + +P + R++D YA+ F++P++ +GV + R+ R EG
Sbjct: 205 AAMICTAGPYAEMLWYLPNV-RRDSDPRYAIYFSIPTNTKGVKFL-SRRGFQPR---EGG 259
Query: 244 DIDLG-NSEFGGHEALVVFDRVFVPNERVFMCK------EYQFAGMMVERFAGYHR--QS 294
+ + +S F +A++V D V +P ER+ K + + + + + +H Q
Sbjct: 260 EFEYPISSRFEESDAVLVLDNVLIPWERIIFFKKPELIEDLMWHTVQLRGWFNWHFVIQH 319
Query: 295 YGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEM---IHLNETLYACGIACSSEGT 351
Y K L G A A+ +G ++++K+ E+ + LNE + + E
Sbjct: 320 YSRLK-----FLAGLAIAIAEASGTSNFINVQEKIGEILIYVALNEAALYASVERAQELP 374
Query: 352 QMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVK 410
+ + I + ++ + + R EI R I+ G + +P+ +DF +PE ++
Sbjct: 375 NITRPDPYISISASHFNMKTVPR-ANEILR---SISAGSSIPIPAGIKDFENPEERKLLD 430
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
KY+A G R+++ L+ ++ A + Y G P
Sbjct: 431 KYMA-MKGLDALERVKMFNLLWDVIGSEAGMRYEQYDRFSRGDP 473
>gi|116052127|ref|YP_789029.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa UCBPP-PA14]
gi|115587348|gb|ABJ13363.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa UCBPP-PA14]
Length = 520
Score = 90.5 bits (223), Expect = 2e-16, Method: Composition-based stats.
Identities = 102/477 (21%), Positives = 206/477 (43%), Gaps = 15/477 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y+ SLR + ++Y G+R+++ HP R + S+A Y L + + L T
Sbjct: 15 TGEEYLASLRD-DREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F +S ++L+ + + T R + A + + +
Sbjct: 74 TGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGR---TPDYKAAFGSALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + K +Q+ L ++ A+ +P DR P +Q D+++ + E + GIVV
Sbjct: 131 FYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRD-KPVDQVK-DVFISVDEEVDGGIVV 188
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H + + A D D+A+ F P + G+ +I R S +
Sbjct: 189 SGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLIC-RPSYELVAGI 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ-SYGGC 298
G+ D +S F ++A++V D+VF+P E V + ++++ + G+ R GC
Sbjct: 248 AGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQ-GGFGRLFPMQGC 306
Query: 299 -KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
++ V D + GA A G + ++ ++ E++ ++ A ++ +G
Sbjct: 307 TRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMYGNASEWYSG 366
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKKYLAG 415
++ + + EI + E + ++ +PS +D +P++ + Y G
Sbjct: 367 AFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRG 426
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G R+++L+L+ + + ++ AGS R+ RQ G K
Sbjct: 427 SGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAVGSGAMK 483
>gi|15599286|ref|NP_252780.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa PAO1]
gi|84319169|ref|ZP_00967572.1| COG2368: Aromatic ring hydroxylase [Pseudomonas aeruginosa C3719]
gi|107103604|ref|ZP_01367522.1| hypothetical protein PaerPA_01004674 [Pseudomonas aeruginosa PACS2]
gi|9950291|gb|AAG07478.1|AE004825_7 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa PAO1]
gi|126168910|gb|EAZ54421.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Pseudomonas
aeruginosa C3719]
Length = 520
Score = 90.5 bits (223), Expect = 2e-16, Method: Composition-based stats.
Identities = 102/477 (21%), Positives = 205/477 (42%), Gaps = 15/477 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y+ SLR + ++Y G+R+++ HP R + S+A Y L + + L T
Sbjct: 15 TGEEYLASLRD-DREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKEKLCWETD 73
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F +S ++L+ + + T R + A + + +
Sbjct: 74 TGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGR---TPDYKAAFGSALGANPG 130
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + K +Q+ L ++ A+ +P DR P +Q D+++ + E + GIVV
Sbjct: 131 FYGRFEDNAKTWYKRIQEACLYLNHAIVNPPIDRD-KPVDQVK-DVFISVDEEVDGGIVV 188
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H + + A D D+A+ F P + G+ +I R S +
Sbjct: 189 SGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLIC-RPSYELVAGI 247
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ-SYGGC 298
G+ D +S F ++A++V D+VF+P E V + ++++ + G+ R GC
Sbjct: 248 AGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQ-GGFGRLFPMQGC 306
Query: 299 -KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
++ V D + GA A G + ++ ++ E++ ++ A ++ G
Sbjct: 307 TRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMYGNASEWHGG 366
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKKYLAG 415
++ + + EI + E + ++ +PS +D +P++ + Y G
Sbjct: 367 AFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRG 426
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G R+++L+L+ + + ++ AGS R+ RQ G K
Sbjct: 427 SGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQAIGSGAMK 483
>gi|116670484|ref|YP_831417.1| 4-hydroxyphenylacetate 3-hydroxylase [Arthrobacter sp. FB24]
gi|116610593|gb|ABK03317.1| 4-hydroxyphenylacetate 3-hydroxylase [Arthrobacter sp. FB24]
Length = 538
Score = 90.5 bits (223), Expect = 2e-16, Method: Composition-based stats.
Identities = 103/449 (22%), Positives = 202/449 (44%), Gaps = 28/449 (6%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYK-HLMTAT 60
MT ++Y++SL+ + +V+ GER+++ HP R S+ A Y E + LM T
Sbjct: 35 MTGDEYIKSLQD-DREVWIYGERVKDVTTHPAFRNSIRMAARLYDAMHKPEMQDKLMVPT 93
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDA-FNAIYSTTYEMD 119
+G + F S EDLK RL + + +G + A + T +
Sbjct: 94 DTGSGGKTMSFFRTPHSVEDLKK----DRLAIETWSRMSYGWLGRSPDYKAAFLGTLGGN 149
Query: 120 QALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGI 179
+ + + K Q+ L + A+ +P DR L P++Q D+++ + + G+
Sbjct: 150 TDFYDPFQENAKRWYKESQEKVLYWNHAIINPPVDRHL-PADQVG-DVFMKVEKETGSGL 207
Query: 180 VVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKM 239
+VSGAK TG+ ++ + I + ++A+ VP DA GV +I R S +
Sbjct: 208 IVSGAKVVATGSAITNYNFI-AHYGLPIKRKEFALICTVPMDAPGVKLI-SRASYAHQAA 265
Query: 240 EEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGC 298
G D +S ++++ +FD+V +P E VF + + + +R ++ G
Sbjct: 266 VMGTPFDYPLSSRMDENDSVFIFDKVLIPWENVFAYGDVEKINNFFPQTGFINRFTFQGV 325
Query: 299 -KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYAC--GIACSSE----G 350
++ D + G A + G ++ ++ E++ +A G+ + + G
Sbjct: 326 IRLATKLDFIAGLLMKALEVAGTQDFRGVQTRVGEVLGWRNMFHALIDGMTLNPDQGPNG 385
Query: 351 TQMKAGNYMIDL-LLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIV 409
T + +Y + + + I + + +D+A GL+ S DF+ PEI P +
Sbjct: 386 TVLPKLDYGLSYRMFMAIGYPRIKEI------IEQDVASGLIYLNSSALDFKTPEIRPYL 439
Query: 410 KKYLAGATGKSTENRMRVLRLIENITLGT 438
KY+ G+ G +R+++++L+ + ++GT
Sbjct: 440 DKYIRGSDGVEAVDRVKLMKLLWD-SIGT 467
>gi|152207437|gb|ABS30825.1| PheA1 [Rhodococcus erythropolis]
Length = 542
Score = 90.1 bits (222), Expect = 3e-16, Method: Composition-based stats.
Identities = 101/448 (22%), Positives = 193/448 (43%), Gaps = 26/448 (5%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTA-T 60
MT ++Y+ SL+ +++ G+R+++ HP R + A Y E+ +T T
Sbjct: 40 MTGDEYISSLQD-GREIWLHGDRVKDVTTHPAFRNPIRMTARLYDALHTGEHVDALTVPT 98
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G F S+ DL + + T R + A + T ++
Sbjct: 99 DTGNGGVTMPFFRTPTSSADLLKERDAIATWARMTYGWMGRS---PDYKASFLGTLHANK 155
Query: 121 ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIV 180
L + + + Q+ L + A+ +P DR L P E D +++ + + + G++
Sbjct: 156 ELYAPFQDNAERWYRESQEKVLYWNHAIINPPVDRQLPPDEVGD--VFMKVEKETDAGLI 213
Query: 181 VSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
VSGAK TG+ ++ + I + +A+ VP DA GV +I C T E
Sbjct: 214 VSGAKVVATGSAITNYNFI-AHYGLPIKKKQFALICTVPMDAPGVKLI-----CRTSYTE 267
Query: 241 EGA------DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQS 294
A D L +S ++ + VFD+V VP + VFM + + R +
Sbjct: 268 HAAVMGSPFDYPL-SSRMDENDTIFVFDKVLVPWKNVFMYGDVNRINAFFPQSGFLPRFT 326
Query: 295 YGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
+ GC ++ V D + G A + G ++ ++ E+I ++ + + + Q
Sbjct: 327 FQGCTRLAVKLDFIAGLLMKALEATGAGGFRGVQTRVGEVIGWRNLFWSLTESMARDPEQ 386
Query: 353 MKAGNYMIDLLLANVCKQN--ITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
G+ +I L + + I P + +D+A GL+ S DF+ P++ P +
Sbjct: 387 W-VGDSVIPKLEYGLTYRMFMIQGYPRIKEIIEQDVASGLIYLPSSSLDFKSPDVRPYLD 445
Query: 411 KYLAGATGKSTENRMRVLRLIENITLGT 438
KY+ G+ G + +R++V++ + + ++GT
Sbjct: 446 KYVRGSDGITAVDRVKVMKALWD-SIGT 472
>gi|83717205|ref|YP_438433.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
thailandensis E264]
gi|83651030|gb|ABC35094.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
thailandensis E264]
Length = 501
Score = 90.1 bits (222), Expect = 3e-16, Method: Composition-based stats.
Identities = 118/503 (23%), Positives = 208/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYLGGERIADVTSHRAFRNAARSIASLYD-ALHGEHRERLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESADDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRF----IEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F ++ K + L ++ A+ +P DR + + D +++H+V
Sbjct: 112 LEAGADYYGDFRRNAADWYKRFAGSGLYLNHAIINPPLDRSKAIHDMRD--VFVHVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+AV F D G+ ++
Sbjct: 170 DSGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAVVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++ +++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDGVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E+I L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELIALWH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITSAMARDPERAPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P++ ++ Y GA + + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPQVKGLIDAYYRGAALEPAQ-RIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 453 IRLDSLTWATRSGQLADCEAFAR 475
>gi|152983981|ref|YP_001346393.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Pseudomonas aeruginosa PA7]
gi|150959139|gb|ABR81164.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Pseudomonas aeruginosa PA7]
Length = 521
Score = 89.7 bits (221), Expect = 4e-16, Method: Composition-based stats.
Identities = 101/477 (21%), Positives = 204/477 (42%), Gaps = 15/477 (3%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYK-LAEMDEYKHLMTATS 61
T E+Y+ SLR + ++Y G+R+++ HP R + S+A Y L + L T
Sbjct: 16 TGEEYLASLRD-DREIYIYGDRVKDVTSHPAFRNAAASMARLYDALHDPQSKDRLCWETD 74
Query: 62 NLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQA 121
G ++F +S ++L+ + + T R + A + + +
Sbjct: 75 TGNGGYTHKFFRYARSADELRQQRDAIAEWSRLTYGWMGR---TPDYKAAFGSALGANPG 131
Query: 122 LGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVV 181
+ + K +Q+ L ++ A+ +P DR P +Q D+++ + E + GI+V
Sbjct: 132 FYGKFEDNARTWYKRIQEACLYLNHAIVNPPIDRD-KPVDQVK-DVFISVDEEVDGGIIV 189
Query: 182 SGAKAHQTGAVNSHEHLIMPTIAMREAD-ADYAVSFAVPSDAEGVIMIYGRQSCDTRKME 240
SGAK T + +H + + A D D+A+ F P + G+ +I R S +
Sbjct: 190 SGAKVVATNSALTHYNFVGQGSAQLLGDNTDFALMFIAPMNTPGMKLIC-RPSYELVAGI 248
Query: 241 EGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ-SYGGC 298
G+ D +S F ++A++V D+VF+P E V + ++++ + G+ R GC
Sbjct: 249 AGSPFDYPLSSRFDENDAILVMDKVFIPWENVLIYRDFERCKQWFPQ-GGFGRLFPMQGC 307
Query: 299 -KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAG 356
++ V D + GA A G + ++ ++ E++ ++ A ++ G
Sbjct: 308 TRLAVKLDFITGALYKALQCTGSLEFRGVQAQVGEVVAWRNLFWSLTDAMHGNASEWHGG 367
Query: 357 NYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKKYLAG 415
++ + + EI + E + ++ +PS +D +P++ + Y G
Sbjct: 368 AFLPSAEALQAYRVLAPQAYPEIKKTIEQVVASGLIYLPSGVRDLHNPQLDKYLSTYCRG 427
Query: 416 ATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKK 472
+ G R+++L+L+ + + ++ AGS R+ RQ G K
Sbjct: 428 SGGMGHRERIKILKLLWDAIGSEFGGRHELYEINYAGSQDEIRMQALRQALGSGAMK 484
>gi|847716|dbj|BAA13105.1| Chlorophenol-4-hydroxylase [Ralstonia pickettii]
Length = 517
Score = 88.6 bits (218), Expect = 9e-16, Method: Composition-based stats.
Identities = 112/507 (22%), Positives = 220/507 (43%), Gaps = 51/507 (10%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T QY+ESL V+ E+I+N HP R A Y L + + +MT
Sbjct: 4 TGTQYLESLND-GRNVWVGNEKIDNVATHPKTRDYAQRHADFYDLHHRPDLQDVMTYIDE 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKM-QRLMGQKTASCFQRCVGMDAFNAIYSTTYEMD-- 119
++ ++ H+ E L+ K K + +M + + F R + N TTY D
Sbjct: 63 GGQRRAMQWFG-HRDKEQLRRKRKYHETVMREMAGASFPRTPDV---NNYVLTTYIDDPA 118
Query: 120 ----QALGTTYH---KRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIV 172
Q++G H + +++++Y +++DL DP+ DR +++ P L +V
Sbjct: 119 PWETQSIGDDGHIKAGKIVDFIRYAREHDLNCAPQFVDPQMDRSNPDAQERSPGL--RVV 176
Query: 173 EVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREA-DADYAVSFAVPSDAEGVIMIYGR 231
E E GIVV+G KA TG + I + R D + A P + GV ++
Sbjct: 177 EKNEKGIVVNGVKAIGTGV--AFADWIHIGVFFRPGIPGDQVIFAATPVNTPGVTIVCRE 234
Query: 232 QSCDTRKME-----EGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
K+E +G ++D + VF+ VF+P VF A + +R
Sbjct: 235 SLVKDDKVEHPLAAQGDELD----------GMTVFENVFIPWSHVFHIGNPNHAKLYPQR 284
Query: 287 FAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIAC 346
+ ++ +++ G A L ++ G K ++ ++ ++I ++ + A IA
Sbjct: 285 VFDWLHYHALIRQMVRAELVAGLAVLITEHIGTNKIPAVQTRVAKLIGFHQAMLAHLIAS 344
Query: 347 SSEGTQMKAGNYMIDLLLANVCK----QNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH 402
G G+Y ++L+ + + +N +++ YE+ D++G + S+ +
Sbjct: 345 EELGFHTPGGHYKPNILIYDFGRALYLENFSQMIYELV----DLSGRSALIFASEDQWND 400
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGT-AAVGYRTESMHGAGSP-QAQRIM 460
++ ++ G G+ +R+++ R+I ++ L + + E+ + G+P Q R++
Sbjct: 401 DKLNGWFERMNNGPVGRP-HDRVKIGRVIRDLFLTDWGSRLFVFENFN--GTPLQGIRML 457
Query: 461 IARQGDLEGK---KKLARAIAHIDESL 484
++ + G KLAR + ID ++
Sbjct: 458 TMQRAEFSGSGPYGKLARQVCGIDSAV 484
>gi|126445435|ref|YP_001061326.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
668]
gi|126224926|gb|ABN88431.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
668]
Length = 494
Score = 88.2 bits (217), Expect = 1e-15, Method: Composition-based stats.
Identities = 117/503 (23%), Positives = 207/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRERLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 112 LEAGAGYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 170 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E+I L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELISLQH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 453 IRLDSLTWATRSGQLADCEAFAR 475
>gi|76817901|ref|YP_336838.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
pseudomallei 1710b]
gi|82537874|ref|ZP_00896869.1| hypothetical protein Bpse110_02000756 [Burkholderia pseudomallei
1106b]
gi|90293233|ref|ZP_01212836.1| hypothetical protein Bpse17_02002101 [Burkholderia pseudomallei
1710a]
gi|100124446|ref|ZP_01329950.1| hypothetical protein BpseS_03001885 [Burkholderia pseudomallei S13]
gi|100233505|ref|ZP_01334546.1| hypothetical protein Bpse4_03002982 [Burkholderia pseudomallei
406e]
gi|126456550|ref|YP_001074273.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
1106a]
gi|134280735|ref|ZP_01767445.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
305]
gi|76582374|gb|ABA51848.1| pyoverdin chromophore biosynthetic protein PvcC [Burkholderia
pseudomallei 1710b]
gi|126230318|gb|ABN93731.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
1106a]
gi|134247757|gb|EBA47841.1| chromophore biosynthetic protein PvcC [Burkholderia pseudomallei
305]
Length = 494
Score = 87.8 bits (216), Expect = 1e-15, Method: Composition-based stats.
Identities = 116/503 (23%), Positives = 207/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRERLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 112 LEAGADYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 170 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E++ L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELVSLQH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 453 IRLDSLTWATRSGQLADCEAFAR 475
>gi|100063566|ref|ZP_01325080.1| hypothetical protein BpseP_03001064 [Burkholderia pseudomallei
Pasteur]
Length = 494
Score = 87.8 bits (216), Expect = 2e-15, Method: Composition-based stats.
Identities = 116/503 (23%), Positives = 207/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRKRLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 112 LEAGADYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 170 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E++ L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELVSLQH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 453 IRLDSLTWATRSGQLADCEAFAR 475
>gi|99911934|ref|ZP_01318736.1| hypothetical protein Bpse1_03001898 [Burkholderia pseudomallei
1655]
Length = 494
Score = 87.4 bits (215), Expect = 2e-15, Method: Composition-based stats.
Identities = 116/503 (23%), Positives = 207/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 3 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRERLTA- 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 60 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 111
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 112 LEAGAGYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 169
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 170 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 225
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 226 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 273
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E++ L
Sbjct: 274 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELVSLQH 333
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 334 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 393
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 394 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 452
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 453 IRLDSLTWATRSGQLADCEAFAR 475
>gi|53721198|ref|YP_110183.1| siderophore biosynthesis-related protein [Burkholderia pseudomallei
K96243]
gi|52211612|emb|CAH37607.1| putative siderophore biosynthesis-related protein [Burkholderia
pseudomallei K96243]
Length = 501
Score = 87.4 bits (215), Expect = 2e-15, Method: Composition-based stats.
Identities = 116/503 (23%), Positives = 207/503 (41%), Gaps = 58/503 (11%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+MT Y++SLR VY GERI + H R + S+A Y A E++ +TA
Sbjct: 10 LMTGNDYLDSLRD-GRNVYVGGERIADVASHRAFRNAARSIASLYD-ALHGEHRERLTA- 66
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCV-GMDAFNAIYSTTYEMD 119
+ G+ +RF +S +DL L Q + R G Y +
Sbjct: 67 PDRHGQITHRFFKPSESPDDL--------LAAQDAIELWSRMTYGFMGRTPDYKAAFMSG 118
Query: 120 QALGTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G Y+ F + + K + L ++ A+ +P DRG + + D +++ +V
Sbjct: 119 LEAGADYYGDFRQNAAGWYKRFAGSGLYLNHAIINPPLDRGKAIHDMRD--VFVRVVGET 176
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR----EADADYAVSFAVPSDAEGVIMIYGR 231
+ GIVVSG K T ++ + P + +AD D+A+ F D G+ ++
Sbjct: 177 DRGIVVSGVKMLATAGALTNATFVAPVASALLEPGKAD-DFAIVFFARMDNPGLSLM--- 232
Query: 232 QSCDTRKMEEGA-----DIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
R E A D L +S F ++++++FDR +P E V + ++ V+R
Sbjct: 233 ----CRPSYEAAATSPFDAPL-SSRFDENDSVLIFDRALIPWEDVLVYRD-------VKR 280
Query: 287 FAGYHRQS--------YGGCKVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G++ S G ++ V +++IG +L NG I+ L E++ L
Sbjct: 281 ATGFYAASGFANLYNFQSGIRLAVKLELMIGLLSLGTQANGTQSFRGIQAALGELVSLQH 340
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGL-MVTMPS 396
L A + + + +G + L A+ + + ++ + L E GG +VT+
Sbjct: 341 LLKTITAAMARDPERTPSGVVVPKLQYASALRIQVPQIWKRVRELMETALGGSPLVTVSG 400
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
D P + ++ Y GA + R+++ +LI + T + H +G+
Sbjct: 401 AADLLDPRVKGLIDAYYRGA-ALEPQQRIKLFKLIWDATGSEFGSRHSVYETHYSGNFDQ 459
Query: 457 QRI----MIARQGDLEGKKKLAR 475
R+ R G L + AR
Sbjct: 460 IRLDSLTWATRSGQLADCEAFAR 482
>gi|108799584|ref|YP_639781.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Mycobacterium sp. MCS]
gi|119868694|ref|YP_938646.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Mycobacterium sp. KMS]
gi|108770003|gb|ABG08725.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component
[Mycobacterium sp. MCS]
gi|119694783|gb|ABL91856.1| 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit
[Mycobacterium sp. KMS]
Length = 452
Score = 85.5 bits (210), Expect = 8e-15, Method: Composition-based stats.
Identities = 104/388 (26%), Positives = 167/388 (43%), Gaps = 21/388 (5%)
Query: 53 YKHLMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRC-----VGMDA 107
Y+ +T TS TG VN + +S EDLK + + +T R + A
Sbjct: 7 YQDQLTFTSPTTGDLVNASFLVPRSVEDLKRRRAAIQTWADETNGFLGRSGDYMNSSLTA 66
Query: 108 FNAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDL 167
A + + D G +R Y +Y ++NDL+ + P+ +R L+ S+Q L
Sbjct: 67 LGAAQTWFAKADPKFG----ERITAYYEYARENDLLATHTLIPPQVNRSLTGSQQGGGQL 122
Query: 168 YLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMR--EADADYAVSFAVPSDAEGV 225
IVE R DGIVV GA+ T A + E L+ P+ +R DA Y+ +FA+ +DA G+
Sbjct: 123 AARIVEERPDGIVVRGARMLATVAPIADELLVFPSTVLRGTPEDAPYSYAFAIQNDAPGL 182
Query: 226 IMIYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFA-GMM 283
R C G+ D + + +A+VVFD VFVPN+RVFM
Sbjct: 183 -----RYLCRGSLHNGGSTFDEPLAARYEEMDAVVVFDDVFVPNDRVFMLGHPDLCNAFY 237
Query: 284 VERFAG-YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYAC 342
E AG V + +G A+ G+ HI++ L E+I E A
Sbjct: 238 AETGAGALMTHQVVTRTVAKTEFFLGLASEIGAAIGIEGFQHIQEDLAELIVDLEIGRAL 297
Query: 343 GIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH 402
A ++G G Y+ N + ++ ++ + ++ +P + D
Sbjct: 298 LRAAEADGAINDWGVYLPRWETLNAARNWYPKVSQRFPQIIRKFSASGLMALPGEADIAS 357
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRL 430
I ++YL GAT T+ R+++ +L
Sbjct: 358 DARADI-EQYLQGATVSGTD-RVQLFKL 383
>gi|15616398|ref|NP_244703.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus halodurans C-125]
gi|10176461|dbj|BAB07555.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus halodurans C-125]
Length = 479
Score = 84.7 bits (208), Expect = 1e-14, Method: Composition-based stats.
Identities = 105/450 (23%), Positives = 191/450 (42%), Gaps = 32/450 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPV-DHPMIRPSMNSVAMTYKLAEMDEYKHLMTA 59
++ Y+E + KL +V+ GE++ + +HP + M S A Y L + K L+T
Sbjct: 3 IIKGSDYLERINKLQNEVWIGGEKVTGAISEHPAFKGIMKSKAALYDLYHHSDKKDLLTC 62
Query: 60 TSNLTGKQVNRFCHLHQST-EDLKDKVKMQRLMGQKTASCFQRCVGM--DAFNAIYSTTY 116
T + + F + T E L+++ + +L+ +++ R A ++ S
Sbjct: 63 WDEKT-NEYHSFSYSQPKTKEQLRNRRQATQLLARESGGTMGRSPDYINTAIMSLGSGGA 121
Query: 117 EMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLY-LHIVEVR 175
M + G K F E ++ D +P+ +R E ++ + +++
Sbjct: 122 GMPKPYGDNARKIFEE----AREKDFSFTHTFINPQVNRSKHYMEYSNEKIIGAKVIDET 177
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
E+G ++ GA+ T + + L++P + + FA+PS+ G+ + R+S
Sbjct: 178 EEGAIIHGARLLATQGGITDQLLVLPA-GGNFIEPSFVYGFAIPSNTPGLKFLC-RESYA 235
Query: 236 TRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER--------F 287
K D L S F +A+VVFD V VP ER+F+ + M + +
Sbjct: 236 HGKTSS-YDYPL-TSHFEEGDAVVVFDHVLVPWERIFIYSDPSQVQTMYDETNMNVLLLY 293
Query: 288 AGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
RQ+ + L+G + V + HI +K+ EMI E + + IA
Sbjct: 294 QAVSRQAVK------SEWLLGLSEWMVRTINVVEHQHIHEKMSEMIISLEIMNSLLIAAE 347
Query: 348 SEGTQMKAGNYMIDLL-LANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIG 406
E K G + D+ L C P + L + A G +++PS+ DF H I
Sbjct: 348 EEAQPNKHGTMIPDIRKLGAACSYYQKTYPRLVDALQQIGASGF-ISLPSEADF-HSSIK 405
Query: 407 PIVKKYLAGATGKSTENRMRVLRLIENITL 436
+ +YL A + E R+R+ RL ++T+
Sbjct: 406 EDLHQYLQAANEDAYE-RVRMFRLAWDLTM 434
>gi|126731665|ref|ZP_01747470.1| putative phenol hydroxylase large subunit [Sagittula stellata E-37]
gi|126707831|gb|EBA06892.1| putative phenol hydroxylase large subunit [Sagittula stellata E-37]
Length = 516
Score = 84.0 bits (206), Expect = 2e-14, Method: Composition-based stats.
Identities = 123/463 (26%), Positives = 207/463 (44%), Gaps = 71/463 (15%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKH-LMTATS 61
T +++ESL+ VY GER+++ HP R S VA Y ++E K L T
Sbjct: 13 TGAEFLESLQDGRC-VYIHGERVKDVTKHPAFRNSSRMVARWYD--RLNEQKDTLGRPTD 69
Query: 62 NLTGKQVNRFCHLHQSTEDL---KDKV-KMQRL----MGQKT--ASCFQRCVGMD-AFNA 110
+G + F +S EDL +D + + QR+ MG+ + F +G + AF
Sbjct: 70 TGSGGWTHPFFMGPKSAEDLIAGRDAIAETQRVANGWMGRAPDYKAAFLGTLGANSAFYG 129
Query: 111 IYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLH 170
Y+ +M ++ R E + Y + A+ +P DR L E D +Y+
Sbjct: 130 EYAENAKM-------WYARTQERLDYW-------NHAIVNPPIDRHLPIEETGD--VYMQ 173
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMP-TIAMREADADYAVSFAVPSDAEGVIMIY 229
+ + + G++VSGAK TG+ +H + I I ++E +A+ F P D+EGV +I
Sbjct: 174 VEKETDAGLIVSGAKVVATGSALTHYNFIAHYGIPIKE--KKFALIFTAPMDSEGVKLI- 230
Query: 230 GRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQF------AGM 282
R S + G D +S +++++VFD+V VP E +F+ + + A
Sbjct: 231 SRSSYELNAAVMGTPFDYPLSSRLDENDSILVFDKVLVPWENIFIYGDVEKINAFFPASG 290
Query: 283 MVERFAGYHRQSYGGCKVGVG-DVLIG--AAALAADYNGVPKASHIKDKLIEMIHLNETL 339
+ RF +G ++ V D + G A AL A +GV + + + E+I
Sbjct: 291 FIPRFT-----LHGVTRLAVKLDFISGLFAKALEATGSGVFRGP--QTAVGEVIAWRNLF 343
Query: 340 YACGIACSS-----EGTQMKAGNYMIDLLLANVCKQNITRL--PYEIARLAE----DIAG 388
+ A EGT G Y +L NV R+ P +R+ E +A
Sbjct: 344 WGLSDAMVKSPVPWEGT----GGY----VLPNVNYGLAYRVFAPMAYSRIKELIERHVAS 395
Query: 389 GLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLI 431
GL+ S DF EI P + +++ G+ G +R+++L+L+
Sbjct: 396 GLIYLPSSAMDFGSEEIRPYIDRFVRGSNGMVAVDRVKLLKLL 438
>gi|111020839|ref|YP_703811.1| aromatic ring hydroxylase [Rhodococcus sp. RHA1]
gi|110820369|gb|ABG95653.1| aromatic ring hydroxylase [Rhodococcus sp. RHA1]
Length = 485
Score = 84.0 bits (206), Expect = 2e-14, Method: Composition-based stats.
Identities = 110/463 (23%), Positives = 192/463 (41%), Gaps = 20/463 (4%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T Y+ SL + V GE+I++ HP P ++A + LA DE + M
Sbjct: 1 MRTGADYLASLNDGRV-VLVDGEKIDDVTTHPAFAPVTRTIAEMFDLAA-DE-ANGMQYV 57
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVG-MDAFNAIYSTTYEMD 119
+ TG NR + +S E+L + + + T R + F A ++ E+
Sbjct: 58 APETGNAANRVFSIPRSREELAQRREAIERWAKHTHGWIGRSPDHVGTFLAAFAAHPEVF 117
Query: 120 QALGT-TYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
A G + E + + D +L V A+ P+ R + S L +VE +G
Sbjct: 118 AAEGGHDFGANVSELYRRLLDENLYVSYAIIPPQVSRATTASGWEGEYLQAGVVEETTEG 177
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
+V+ G++ TG + E + + D D+AV F VP++A G+ R
Sbjct: 178 LVIRGSQMLATGGAIADEIFVSCIKPLGPDDKDFAVGFVVPTNAPGLKQYVRRPYIPA-- 235
Query: 239 MEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEY-----QFAGMMVERFAGYHRQ 293
D L + ++L+VFD V VP +RVF+ ++ QF + Q
Sbjct: 236 ATSSFDYPL-TCRYDEPDSLLVFDDVLVPWDRVFVDRDTTGVRRQFFETGAHVLGNWQAQ 294
Query: 294 SYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQM 353
K+ + + G A NGV K +++KL E+ L + + +A
Sbjct: 295 IRFATKL---EFIAGVARRVTQVNGVDKIPSVQEKLGELAALVSGVRSAVLAAEYTAEPD 351
Query: 354 KAGNYMI--DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKK 411
AG ++ L ++ Q+ P IA L + + GG++ S +D P ++
Sbjct: 352 SAGMWLPGRQALYGSMGLQS-EIYPRVIAILRDLVGGGVLQLPSSVKDLTSPLTSRDIEH 410
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
Y+ + G +E R+++ +L +I A ++ M AG+P
Sbjct: 411 YVQ-SPGVPSEERVKLFKLAWDIIGSEFAGRHQQYEMFYAGAP 452
>gi|37527879|ref|NP_931224.1| hypothetical protein plu4027 [Photorhabdus luminescens subsp.
laumondii TTO1]
gi|36787315|emb|CAE16399.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii
TTO1]
Length = 519
Score = 83.2 bits (204), Expect = 4e-14, Method: Composition-based stats.
Identities = 97/485 (20%), Positives = 210/485 (43%), Gaps = 32/485 (6%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
TS++Y+ SL+ + ++Y GER+++ HP R + S+ Y E + + ++
Sbjct: 15 TSKEYLNSLQD-SREIYIYGERVKDVTIHPAFRNTAASIGQLYDALHAPETHNALCWNTD 73
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQAL 122
TG + + H D+++ QR A ++ G Y +
Sbjct: 74 -TGNE--GYTHKFFRFATNPDELRQQR---DAIAEWSRQSYGWMGRTPDYKAAFSCALGA 127
Query: 123 GTTYHKRFIE----YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
++ +F + K +Q++ + + A+ +P DR P+++ D+++ + + + G
Sbjct: 128 YPEFYGQFSNNARAWYKRIQESCMYFNHAIVNPPIDRH-KPADEVK-DVFIQLEKETDAG 185
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
I+VSGAK T + +H + I+ + + D+ + F P +A G+ +I R S +
Sbjct: 186 IIVSGAKVVATNSALTHYNFIVGSAQDIGDNPDFTLMFIAPMNANGMKLI-SRASYELAA 244
Query: 239 MEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQ-SYG 296
G+ D +S F ++A++V D+V +P E + + ++ + + +G+ R
Sbjct: 245 GTTGSPFDYPLSSRFDENDAILVMDKVLIPWENILIYRDVGSSRHWAVQ-SGFARLFPMQ 303
Query: 297 GC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMK 354
C ++ V D + + + GV ++ L E++ ++ A +E +
Sbjct: 304 ACVRLAVKLDFITALLQKSLECTGVVDFRGVQADLGEVVAWRNLFWSLTDAMWAEAKPWE 363
Query: 355 AGNYMID-------LLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGP 407
Y+ D L++A + I + + ++ GL+ S +D +PEI
Sbjct: 364 GNAYLPDTQAIQTYLVMAPIAYTKIRNI------IESNVTSGLIYLPSSIRDMNNPEINK 417
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDL 467
+++Y+ G+ G R+++L+L+ + ++ ++ AGS R+ R
Sbjct: 418 YLEQYVRGSNGIDYVERIKILKLMWDAIGSEFGSRHQLYEINYAGSQDGVRLQCLRHAYS 477
Query: 468 EGKKK 472
G K
Sbjct: 478 SGNMK 482
>gi|146303772|ref|YP_001191088.1| 4-hydroxyphenylacetate 3-hydroxylase [Metallosphaera sedula DSM
5348]
gi|145702022|gb|ABP95164.1| 4-hydroxyphenylacetate 3-hydroxylase [Metallosphaera sedula DSM
5348]
Length = 488
Score = 81.6 bits (200), Expect = 1e-13, Method: Composition-based stats.
Identities = 109/472 (23%), Positives = 198/472 (41%), Gaps = 50/472 (10%)
Query: 7 YVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLA-EMDEYKHLMTATSNLTG 65
Y+ES+ K Y+ GE + + V+HP R + +VA Y L ++D + T
Sbjct: 8 YIESISKNPPVTYYEGEVVSDVVNHPAFRIPVKTVASYYDLHWKVDGLRVYNRDVGEETS 67
Query: 66 KQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEM------D 119
+ R +S EDL +G+ ++ G + Y + M +
Sbjct: 68 ISLVR----PRSKEDLLK-------LGEGLVKIYEFYRGFFGRSPDYMNLWTMVFFAHAE 116
Query: 120 QALGTTYHKRFIE-YMKYVQDN---DLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
G + RF+E M+ +++ D A+ P DR PS+ DP + + I E R
Sbjct: 117 DYFGKHFGSRFMENAMEIYRESTRKDHFYTHAIVAPMYDRSRPPSQWEDPYIQIGITEER 176
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
+G+VV GA T + +P + R++D YA+ F++P+ +GV I R+
Sbjct: 177 PEGVVVRGAAMICTAGPYAEMLWYLPNM-RRDSDPRYALYFSIPTTTKGVRFI-ARRGFQ 234
Query: 236 TRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAG----- 289
R EG + + +S + +A++V D V VP +R+ K+ + ++ G
Sbjct: 235 PR---EGGEFEYPISSRWDEADAILVLDNVLVPWDRIIFFKKPELIEDLMWHTVGLRGWF 291
Query: 290 ---YHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEM---IHLNETLYACG 343
+ Q Y K L G A + G ++++K+ E+ + LNE
Sbjct: 292 NWHFMIQHYTRLK-----FLAGLAMTITEAAGTSTFINVQEKIGEILLYVALNEAALYGS 346
Query: 344 IACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPS-QQDFRH 402
+A + E + + I + ++ + + R EI RL I+ G + +P+ +DF +
Sbjct: 347 VARAQELPNIVRPDPYISISASHFNMKAVPR-ANEILRL---ISAGSSIPIPAGAKDFTN 402
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
PE ++KY+A G R++ L+ ++ + Y G P
Sbjct: 403 PEERAYLEKYMA-MKGFDALERVKTFNLLWDVIGSEVGMRYEQYDRFSRGDP 453
>gi|54025025|ref|YP_119267.1| putative phenol hydroxylase large subunit [Nocardia farcinica IFM
10152]
gi|54016533|dbj|BAD57903.1| putative phenol hydroxylase large subunit [Nocardia farcinica IFM
10152]
Length = 479
Score = 81.6 bits (200), Expect = 1e-13, Method: Composition-based stats.
Identities = 101/416 (24%), Positives = 180/416 (43%), Gaps = 33/416 (7%)
Query: 31 HPMIRPSMNSVAMTYKLAEMDEYK-HLMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQR 89
HP R S SVA Y E + L T G + F S EDL
Sbjct: 7 HPAFRNSARSVARLYDALHRPEARGTLAVPTDTGNGGFTHPFFKTAHSAEDL-------- 58
Query: 90 LMGQKTASCFQRCV----GMDA-FNAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVV 144
L+ + + +QR V G + A + T + Y + Q+ L +
Sbjct: 59 LLARDAITTWQREVYGWMGRSPDYKASFLGTLGANADFYGQYRDNARRWYTRAQERVLYL 118
Query: 145 DGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMP-TI 203
+ A+ +P DR E AD + +H+VE + G+VVSGAK TG+ ++ + I +
Sbjct: 119 NHAIVNPPIDRDKPADETAD--VCVHVVEETDAGLVVSGAKVVATGSAITNANFIAHYGL 176
Query: 204 AMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFD 262
+R+ + + + F VP D+ G+ ++ R S + G D +S F ++A++VFD
Sbjct: 177 PLRKKE--FGLIFTVPMDSPGLKLLC-RTSYEMNAAVLGTPFDYPLSSRFDENDAIMVFD 233
Query: 263 RVFVPNERVFMCKEYQFAGMMVERFAGY-HRQSYGGC-KVGVG-DVLIGAAALAADYNGV 319
RV VP E VF G +++ +G+ R + GC ++ V D + G A G
Sbjct: 234 RVLVPWENVFAYDVETTNGFVMK--SGFLSRFMFHGCARLAVKLDFIAGCVLKAVQMTGT 291
Query: 320 PKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEI 379
++ ++ E+++ + + A + G +L N T +
Sbjct: 292 AGFRGVQMQVGEILNWRDMFWGLSDAMAKSPDSWVNGAVQPNL---NYGLAYRTFMGVGY 348
Query: 380 ARLAEDI----AGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLI 431
R+ E I GL+ +D+++P+I P + +Y+ G+ G + +R+++L+L+
Sbjct: 349 PRIKEIIQQTLGSGLIYLNSHAEDWKNPDIRPYLDQYVRGSNGVAAVDRVQLLKLL 404
>gi|73541275|ref|YP_295795.1| 4-hydroxyphenylacetate 3-hydroxylase [Ralstonia eutropha JMP134]
gi|21489735|gb|AAM55214.1|AF498371_1 2,4,6-trichlorophenol monooxygenase; TcpA [Ralstonia eutropha]
gi|72118688|gb|AAZ60951.1| 4-hydroxyphenylacetate 3-hydroxylase [Ralstonia eutropha JMP134]
Length = 517
Score = 80.9 bits (198), Expect = 2e-13, Method: Composition-based stats.
Identities = 103/454 (22%), Positives = 190/454 (41%), Gaps = 44/454 (9%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T +QY+ESL V+ E+I+N HP R A Y L + + +MT
Sbjct: 4 TGKQYLESLND-GRNVWVGNEKIDNVATHPKTRDYAQRHADFYDLHHRPDLQDVMTFVDK 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKM-QRLMGQKTASCFQRCVGMDAFNAIYST------T 115
G++ H E L+ K K + +M + + F R D N + T
Sbjct: 63 -DGERRTMQWFGHYDKEQLRRKRKYHETIMREMAGASFPRTP--DVNNYVLQTYIDDPSP 119
Query: 116 YEMDQ--ALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+E A G K ++++ + + +DL DP+ DR ++Q P L ++E
Sbjct: 120 WETQTIGAEGKVKAKNIVDFVNFAKKHDLNCAPQFVDPQMDRSNPDAQQRSPGL--RVIE 177
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREA-DADYAVSFAVPSDAEGVIMIYGRQ 232
+ GIVVSG KA TG + I + R D + A P + GV ++
Sbjct: 178 KNDKGIVVSGVKAIGTGV--AFADWIHIGVFFRPGIPGDQIIFAATPVNTPGVTIV---- 231
Query: 233 SCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER---FAG 289
C ++E S+ + + VFD VF+P VF + A + +R +
Sbjct: 232 -CRESVVKEDPIEHPLASQGDELDGMTVFDNVFIPWSHVFHLGNPEHAKLYPQRVFDWLH 290
Query: 290 YH---RQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIAC 346
YH RQS +++ G A L ++ G K ++ ++ ++I ++ + A +A
Sbjct: 291 YHALIRQSVR------AELMAGLAILITEHIGTNKIPAVQTRVAKLIGFHQAMLAHIVAS 344
Query: 347 SSEGTQMKAGNYMIDLLLANVCK----QNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH 402
G G Y ++L+ + + +N +++ YE+ D++G + S+ +
Sbjct: 345 EELGFHTPGGAYKPNILIYDFGRALYLENFSQMIYELV----DLSGRSALIFASEDQWND 400
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRLIENITL 436
+ ++ G G+ +R+++ R+I ++ L
Sbjct: 401 EALNGWFERMNNGPVGQP-HDRVKIGRVIRDLFL 433
>gi|16759979|ref|NP_455596.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Typhi str. CT18]
gi|29142250|ref|NP_805592.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Typhi Ty2]
gi|56413907|ref|YP_150982.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Paratyphi A str. ATCC 9150]
gi|25528375|pir||AF0630 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3) [imported] -
Salmonella enterica subsp. enterica serovar Typhi
(strain CT18)
gi|16502273|emb|CAD08225.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Typhi]
gi|29137880|gb|AAO69441.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Typhi Ty2]
gi|56128164|gb|AAV77670.1| 4-hydroxyphenylacetate 3-monooxygenase [Salmonella enterica subsp.
enterica serovar Paratyphi A str. ATCC 9150]
Length = 435
Score = 80.5 bits (197), Expect = 2e-13, Method: Composition-based stats.
Identities = 81/359 (22%), Positives = 159/359 (44%), Gaps = 18/359 (5%)
Query: 137 VQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAKAHQTGAVNSHE 196
+Q+ L + A+ +P DR P+++ D+Y+ + + + GI+VSGAK T + +H
Sbjct: 61 IQETGLYFNHAIVNPPIDRH-KPADEVK-DVYIKLEKETDAGIIVSGAKVVATNSALTHY 118
Query: 197 HLI-MPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADIDLG-NSEFGG 254
++I + + + D+A+ F P DAEGV +I R S + G+ D +S F
Sbjct: 119 NMIGFGSAQVMGENPDFALMFVAPMDAEGVKLI-SRASYEMVAGATGSPFDYPLSSRFDE 177
Query: 255 HEALVVFDRVFVPNERVFM------CKEYQFAGMMVERFAGYHRQSYGGCKVGVGDVLIG 308
++A++V D+V +P E V + C+ + G Y Q+ V + D +
Sbjct: 178 NDAILVMDKVLIPWENVLIYRDFDRCRRWTMEGGFARM---YPLQACVRLAVKL-DFITA 233
Query: 309 AAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLLANVC 368
+ + G + ++ L E++ +A + SE T G ++ D
Sbjct: 234 LLKKSLECTGTVEFRGVQADLGEVVAWRNMFWALSDSMCSEATPWVNGAWLPDHAALQTY 293
Query: 369 KQNITRLPYEIARLAE-DIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKSTENRMRV 427
+ +I + E ++ GL+ S +D +P+I + KY+ G+ G R+++
Sbjct: 294 RVMAPMAYAKIKNIIERNVTSGLIYLPSSARDLNNPQIDQYLAKYVRGSNGMDHVERIKI 353
Query: 428 LRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHIDESLDK 486
L+L+ + + ++ +GS R+ RQ G + + +A +D L +
Sbjct: 354 LKLMWDAIGSEFGGRHELYEINYSGSQDEIRLQCLRQAQSSG--NMDKMMAMVDRCLSE 410
>gi|47568711|ref|ZP_00239407.1| 4-hydroxyphenylacetate-3-hydroxylase, putative [Bacillus cereus
G9241]
gi|47554605|gb|EAL12960.1| 4-hydroxyphenylacetate-3-hydroxylase, putative [Bacillus cereus
G9241]
Length = 476
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 78/315 (24%), Positives = 136/315 (43%), Gaps = 14/315 (4%)
Query: 126 YHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAK 185
+ + Y + +DN L + DP+ +R A L + + DGI +SGAK
Sbjct: 126 FPDKIASYYEKARDNHLFLSVVQRDPQINRSTESMLNATDLGLLRVTKETSDGIYLSGAK 185
Query: 186 AHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADI 245
T + S++ LI P + +A D A V +++ G+ M+ +T + I
Sbjct: 186 MIGTASPYSNDLLIYPLTKLTDAQKDLAHFLIVAANSPGLHMVCREPYANTTSSTVDSPI 245
Query: 246 DLGNSEFGGHEALVVFDRVFVPNERVFMCKE----YQFAGMMVERFAGYHRQSYGGCKVG 301
+S++ +AL++FD VFVP ERV + + YH+ ++
Sbjct: 246 ---SSQYDEMDALLIFDNVFVPWERVLLYNNPEAIWAIKSDTASSSLAYHQAI---VRLL 299
Query: 302 VGDVLIGAAALA-ADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
+ I A A A+ G H+++KL E+I ET+ A IA EGT + Y+
Sbjct: 300 IKLEFITAIAFEIAEAIGAHTYLHVQEKLGELIMQIETIRALLIAAEVEGTTNETKTYLP 359
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQ-DFRHPEIGPIVKKYLAGATGK 419
+ + ++ + + I G + +PS DF+ P I ++KK+ G T
Sbjct: 360 NFKYIETARNLGSKYYPRAIEILQLIGAGGFIQLPSSSIDFQSP-IANLLKKHFKG-TNI 417
Query: 420 STENRMRVLRLIENI 434
E R ++ +L +I
Sbjct: 418 DAEQRTKLFKLAWDI 432
>gi|126654193|ref|ZP_01725994.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus sp. B14905]
gi|126589332|gb|EAZ83486.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus sp. B14905]
Length = 474
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 100/449 (22%), Positives = 180/449 (40%), Gaps = 34/449 (7%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPV-DHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
MT +QY+E + LN + GE + V +HP + M S A + L + Y MT
Sbjct: 1 MTGQQYMERIDALNTYISIDGEVVTGKVSEHPAFKGIMQSQAKLFDLQHQEAYLEKMTYE 60
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
S + ++V S EDL + R +T R + Y T M
Sbjct: 61 SPTSKERVGMSFLQVMSPEDLVKRRMAAREWALQTNGLMGR-------SPDYMNTTLMAL 113
Query: 121 ALGTTYHK--------RFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIV 172
A + + K +++ +Y ++ND+ + +P+ +R E + + IV
Sbjct: 114 ASASNFLKDKPNCFPDHLLKFYEYARENDISMTHTFIEPQVNRKRYYYEDEEVTIAAKIV 173
Query: 173 EVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQ 232
+G+V+ GA+ T + E L++ T E F++PS+ +G+ +
Sbjct: 174 AKTGEGLVIKGARLLATQGGITDELLVLSTNGYDEGK---GFGFSIPSNTKGLKFL---- 226
Query: 233 SCDTRKMEEGADIDLG---NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAG--MMVERF 287
R+ G D ++ F +A+VVFD V VP ERVF + + A M V F
Sbjct: 227 ---CRQSFVGGDSKFDHPLSARFEEMDAIVVFDDVVVPWERVFYYENVEVANQFMNVSGF 283
Query: 288 AGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
Y ++ + +G D + H+ K++++I ET+ A +
Sbjct: 284 QAYTLHHVLSRQIAKTEFTLGIVQTIVDTINIGDYQHVHQKVVDVIVALETMKALQLKSE 343
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGP 407
E + G DL V ++ + + + ++++PS + F + G
Sbjct: 344 IEAQRDSFGFIRPDLSTLQVAIHIFPKVYPTFTDIIQLLGASGLMSIPSAKAFA-TDNGD 402
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITL 436
+ YL K E R++ RL ++T+
Sbjct: 403 L-DHYLQSFQDKG-EERVKKFRLAWDLTM 429
>gi|119434078|gb|ABL75143.1| 4-nitrophenol monooxygenase [Arthrobacter sp. JS443]
Length = 535
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 107/441 (24%), Positives = 183/441 (41%), Gaps = 21/441 (4%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T ++Y+ESLR +VY GE IE+ HP + ++A Y L E + L+T
Sbjct: 1 MRTGKEYLESLRD-GRQVYVGGELIEDVTTHPKTKGYAQAIAEYYDLHLKPENQDLLTFV 59
Query: 61 SNLTGKQVNRFCHLHQSTEDL-KDKVKMQRLMGQKTASCFQRC-VGMDA--FNAIYSTTY 116
GK+ + L +S ED+ K + + F R GM+ F +
Sbjct: 60 DE-NGKRESMHWFLPRSKEDVVKRRNYADFIFRHFQGGIFTRPPAGMNVVMFTQVDDQEP 118
Query: 117 EMDQALGTTYHK----RFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIV 172
+ + H+ + + V DL V D + DRG + P L I+
Sbjct: 119 WAENSRFKNGHRDLSGNIQRHWEEVTSKDLAVSPMFVDVQYDRGRDDAMAETP--MLSII 176
Query: 173 EVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQ 232
E ++GIVV G KA T ++ +L++ + A+ V VP GV ++ R+
Sbjct: 177 EENDEGIVVRGWKAIGT-SIPFVNNLLIGNLWRPGQTAEQTVYAMVPLATPGVSVV-ARE 234
Query: 233 SCDTRKMEEGADIDLGNSEFGGH-EALVVFDRVFVPNERVFMCKEYQFAGMMVER-FAGY 290
S R + D + G + +V FD V +P +V A +R F
Sbjct: 235 S---RAQPDADPYDRPLATLGDELDGMVYFDNVLIPWAQVQHVGNPDHAKWYPQRQFDWV 291
Query: 291 HRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEG 350
H ++ V ++++G L G K ++ +L E+I ET A IA G
Sbjct: 292 HLETQIRQTVH-AELMVGLGLLITQSLGTSKNPVVQSQLAELIRFRETCRAFMIAAEETG 350
Query: 351 TQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVK 410
G Y + + + + + +E+ + + G +V P+ ++ HP IGP ++
Sbjct: 351 FHTPGGLYKPNNIFIDFGRAHYLEHQHEMVNMLIEFCGRGIVIQPTARELDHPYIGPKLQ 410
Query: 411 KYLAGATGKSTENRMRVLRLI 431
+ L G+ S +R+++ R I
Sbjct: 411 EALRGSE-ISARDRIKIFRQI 430
>gi|42781661|ref|NP_978908.1| 4-hydroxyphenylacetate 3-hydroxylase family family [Bacillus cereus
ATCC 10987]
gi|42737584|gb|AAS41516.1| 4-hydroxyphenylacetate 3-hydroxylase family protein [Bacillus
cereus ATCC 10987]
Length = 476
Score = 80.1 bits (196), Expect = 3e-13, Method: Composition-based stats.
Identities = 77/315 (24%), Positives = 137/315 (43%), Gaps = 14/315 (4%)
Query: 126 YHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAK 185
+ + Y + +DN L + DP+ +R A+ L + + DGI +SGAK
Sbjct: 126 FPDKIASYYEKARDNHLFLSVVQRDPQINRSTESMLNANDLGLLRVTKETSDGIYLSGAK 185
Query: 186 AHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADI 245
T + S++ LI P + +A D A V +++ G+ M+ +T + I
Sbjct: 186 MIGTASPYSNDLLIYPLTKLTDAQKDLAHFLIVAANSPGLHMVCREPYANTTSSTVDSPI 245
Query: 246 DLGNSEFGGHEALVVFDRVFVPNERVFMCKE----YQFAGMMVERFAGYHRQSYGGCKVG 301
+S++ +AL++FD VFVP ERV + + YH+ ++
Sbjct: 246 ---SSQYDEMDALLIFDNVFVPWERVLLYNNPEAIWAIKSDTASSSLAYHQAI---VRLL 299
Query: 302 VGDVLIGAAALA-ADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMI 360
+ I A A A+ G H+++KL E+I ET+ A IA EG+ + Y+
Sbjct: 300 IKLEFITAIAFEIAEAIGAHTYLHVQEKLGELIMQIETIRALLIAAEVEGSTNETKTYLP 359
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQ-DFRHPEIGPIVKKYLAGATGK 419
+ + ++ + + I G + +PS DF+ P I ++KK+ G T
Sbjct: 360 NFKYIETARNLGSKYYPRAIEILQLIGAGGFIQLPSSSIDFQSP-IADLLKKHFKG-TNI 417
Query: 420 STENRMRVLRLIENI 434
E R ++ +L +I
Sbjct: 418 DAEQRTKLFKLAWDI 432
>gi|37547923|gb|AAN08754.1| putative chlorophenol monooxygenase large subunit [Arthrobacter
chlorophenolicus]
Length = 535
Score = 79.7 bits (195), Expect = 4e-13, Method: Composition-based stats.
Identities = 110/446 (24%), Positives = 186/446 (41%), Gaps = 31/446 (6%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T ++Y+ESLR KVY GE IE+ HP + ++A Y L E + L+T
Sbjct: 1 MRTGKEYLESLRD-GRKVYVGGELIEDVTTHPKTKGYAQAIAEYYDLHLKPENQDLLTFV 59
Query: 61 SNLTGKQVNRFCHLHQSTED-LKDKVKMQRLMGQKTASCFQRC-VGMDAFNAIYSTTYEM 118
GK+ + L +S ED +K + + F R GM N + T ++
Sbjct: 60 DE-NGKRESMHWFLPRSKEDVIKRRNYADFIFRHFQGGIFTRPPAGM---NVVMFT--QV 113
Query: 119 DQALGTTYHKRFIEYMKYVQDN-----------DLVVDGAMTDPKGDRGLSPSEQADPDL 167
D + RF + + N DL V D + DRG S P
Sbjct: 114 DDQEPWAENSRFKNGHRDLSGNIQRHWDEVTAKDLAVSPMFVDVQYDRGRDDSMAETP-- 171
Query: 168 YLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIM 227
L I+E ++GIVV G KA T ++ +L++ + A+ + VP GV +
Sbjct: 172 MLSIIEENDEGIVVRGWKAIGT-SIPFVNNLLIGNLWRPGQTAEQTIYAMVPLATPGVSV 230
Query: 228 IYGRQSCDTRKMEEGADIDLGNSEFGGH-EALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
+ R+S R + D + G + +V FD V + ++V + A +R
Sbjct: 231 V-ARES---RAQPDADPYDRPLATLGDELDGMVYFDDVLITWDQVQHVGNPEHAKWYPQR 286
Query: 287 -FAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
F H ++ V ++++G L G K ++ +L E+I ET A IA
Sbjct: 287 QFDWVHLETQIRQTVH-AELMVGLGLLITQALGTSKNPVVQSQLAELIRFRETCRAFMIA 345
Query: 346 CSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEI 405
G G Y + + + + + +E + + G +V P++++ HP I
Sbjct: 346 AEETGFHTPGGLYKPNNIFIDFGRAHYLEHQHEFVNMLIEFCGRGIVIQPTKRELDHPYI 405
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLI 431
GP +++ L G+ S +R+++ R I
Sbjct: 406 GPKLQEALRGSE-ISARDRIKIFRQI 430
>gi|56420673|ref|YP_147991.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus kaustophilus
HTA426]
gi|56380515|dbj|BAD76423.1| 4-hydroxyphenylacetate-3-hydroxylase [Geobacillus kaustophilus
HTA426]
Length = 481
Score = 78.6 bits (192), Expect = 8e-13, Method: Composition-based stats.
Identities = 103/462 (22%), Positives = 194/462 (41%), Gaps = 42/462 (9%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPV-DHPMIRPSMNSVAMTYKLAEMDEYKH---- 55
++ +QY+E + L ++ G+++ + +HP + S A Y A+ + K
Sbjct: 3 IIRGDQYIERIDNLQSNIWINGQQVRGKLSEHPAFAGVIRSQARLYD-AQHNPNKQPVLT 61
Query: 56 LMTATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTT 115
T+T L G R KD ++ +RL Q+ A + GM + Y T
Sbjct: 62 FRTSTGELAGAAFLR--------PTTKDDLEHRRLAFQEWA---RLTAGMMGRSPDYMNT 110
Query: 116 YEMDQALGTTY----HKRFIEYMKYVQD----NDLVVDGAMTDPKGDRGLSPSEQADPDL 167
M A + H + E+++ + + NDL +P+ +R L E+ +
Sbjct: 111 AVMALASAADFFGQQHPSYAEHIERLYERAINNDLSFTHTFVNPQVNRSLGYMEEDGEPI 170
Query: 168 YLHIVEVREDGIVVSGAK--AHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGV 225
++ DG+V+ GA+ A+Q G + E L++P D +Y +F++PS+ G+
Sbjct: 171 AAKVIRETTDGLVIKGARLLANQGGMTD--ELLVLPAGGTLLGD-EYMYAFSIPSNTPGL 227
Query: 226 IMIYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMV 284
I C + D ++ F +A+VVFD V VP +RVF K+ A +
Sbjct: 228 KFI-----CRPSFAAGASSFDAPLSAHFDEIDAIVVFDDVLVPWDRVFFYKDAWVAKELD 282
Query: 285 ER--FAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYAC 342
E A ++ + +G L ++ + H+++K+ E+ E L A
Sbjct: 283 EETHLAIMLLHQVLARRIVKTEFFLGTVELLSEAIQIGGYQHVQEKIGEIAAALEALRAM 342
Query: 343 GIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRH 402
+A + + G + D RL + + + +V +P++ DF
Sbjct: 343 LLAAELQAKPDRRGTMVPDPAPLYAAAFLYPRLYPRFVDIVQLLGASGLVCLPTEADFSS 402
Query: 403 PEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYR 444
P + P +++YL AT E R+++ R ++ + +A G R
Sbjct: 403 P-LRPDLERYLQAAT-LPAEQRVQLFRFAWDLAM--SAFGTR 440
>gi|68229094|ref|ZP_00568292.1| 4-hydroxyphenylacetate 3-hydroxylase [Frankia sp. EAN1pec]
gi|68203273|gb|EAN17447.1| 4-hydroxyphenylacetate 3-hydroxylase [Frankia sp. EAN1pec]
Length = 304
Score = 77.8 bits (190), Expect = 2e-12, Method: Composition-based stats.
Identities = 59/169 (34%), Positives = 88/169 (52%), Gaps = 17/169 (10%)
Query: 115 TYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEV 174
+++ Q LG YH+R + DL +T+P+ DR S SEQ + DLY+ V+
Sbjct: 19 SFDGRQNLGA-YHRR-------MAGGDLYQAFTITNPQIDRTRSASEQEEDDLYVRAVKE 70
Query: 175 REDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSC 234
+ GIVV GAK T AV +E ++ + D DYA+SF+VP D G+ ++ R S
Sbjct: 71 LDGGIVVRGAKMTGTAAVFGNEIIVGTIEPLPPQDVDYALSFSVPIDTPGLKLV-SRAS- 128
Query: 235 DTRKMEEGADIDLGN---SEFGGHEALVVFDRVFVPNERVFMCKEYQFA 280
E A N S F ++AL+V D VFVP +RV + ++ + A
Sbjct: 129 ----YEASARSVFDNPLSSRFDENDALLVCDDVFVPWDRVLVYRDTRAA 173
>gi|119961487|ref|YP_946424.1| putative 4-hydroxyphenylacetate 3-monooxygenase [Arthrobacter
aurescens TC1]
gi|119948346|gb|ABM07257.1| putative 4-hydroxyphenylacetate 3-monooxygenase [Arthrobacter
aurescens TC1]
Length = 490
Score = 77.0 bits (188), Expect = 3e-12, Method: Composition-based stats.
Identities = 108/469 (23%), Positives = 195/469 (41%), Gaps = 33/469 (7%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T ++Y++SL V GE + N ++HP ++A + +A E + M
Sbjct: 1 MRTGKEYLKSLND-GRSVILDGEVVGNVLEHPAFANVARTMAELFDIAADPE--NGMQFH 57
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVG-----MDAFNAIYSTT 115
S NR ++ E+L ++R +K A VG + F A + +
Sbjct: 58 SEEIDGPANRTFAAPRTQEELV----LRRQAIEKWAKHTHGWVGRSPDHVGTFFAAFGSH 113
Query: 116 YEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVR 175
++ + + Y K + +L + A+ P+ R + S L + +V
Sbjct: 114 PDVFKNDERDFAGNVERYYKKILSENLYLSYAIIPPQVSRATTASGWEGEYLQVGVVRET 173
Query: 176 EDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCD 235
E+GI+V G++ TGA + E + + D D+AVSFA+P +G + +Y R
Sbjct: 174 EEGIIVRGSQMLATGAAIADEVFVTCIKPLGPDDVDFAVSFAIPVATDG-LKLYCR---- 228
Query: 236 TRKMEEGADIDLG---NSEFGGHEALVVFDRVFVPNERVFMCKEY-----QFAGMMVERF 287
R A D S + +ALVVFD V +P +RVF+ + QF
Sbjct: 229 -RPFAPAATSDFDYPLTSHYDEPDALVVFDDVLIPWDRVFINRNIDTLRRQFFDTGAHAL 287
Query: 288 AGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACS 347
+ Q K+ + A NG K +++KL E+ + +++ + +A
Sbjct: 288 GNWQAQIRFSTKL---KFIASVARKVTQVNGTDKIPGVQEKLGELAAIVQSVESAVLAAE 344
Query: 348 SEGTQMKAGNYM--IDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEI 405
T AG + L + Q+ T P I+ L + + GG++ S D
Sbjct: 345 YTATTDDAGMRVPGKSALYGAMGLQSET-YPRVISILRDVVGGGVLQLPSSIADMTSSVT 403
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSP 454
P +++Y+ + G ++E R+++ +L +I A ++ M AG+P
Sbjct: 404 RPDMERYVQ-SPGVTSEERVKLFKLAWDIIGSEFAGRHQQYEMFYAGAP 451
>gi|118590246|ref|ZP_01547649.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Stappia
aggregata IAM 12614]
gi|118437218|gb|EAV43856.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Stappia
aggregata IAM 12614]
Length = 516
Score = 76.3 bits (186), Expect = 4e-12, Method: Composition-based stats.
Identities = 103/494 (20%), Positives = 210/494 (42%), Gaps = 22/494 (4%)
Query: 2 MTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKL--AEMDEYKHLMTA 59
MT ++++SL+ VYF GER+ + HP R S+ S+A Y + D +++TA
Sbjct: 21 MTGAEFIDSLQDERC-VYFNGERVADLTGHPAFRNSVRSLARLYDALHQDHDSGTNILTA 79
Query: 60 TSNLT-GKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEM 118
++ +R+ + +S EDL + Q+ + + + + A T +
Sbjct: 80 PADADPSGYTHRYFKVARSAEDL---LGQQKAIAEWAKLSYGWMGRSPDYKAAIVNTLDA 136
Query: 119 DQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDG 178
+ A + + Q ++ A+ +P DR P A D+ +H+V+ + G
Sbjct: 137 NAAYYGPFADNARRWYHLAQQRTYFMNHAVANPPIDRA-KPFSDAK-DILVHVVKETDAG 194
Query: 179 IVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRK 238
+ +SGAK T A +H + + + A F + G+ +I R S +
Sbjct: 195 LYLSGAKVVATSAALTHYNFLSHHAVSETNEPPTAFMFFLDMSTPGIKLIC-RNSYEYAA 253
Query: 239 MEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERF--AGYHRQS- 294
+ D +S F ++A++V D VFVP E V + Y A ++ GY + +
Sbjct: 254 SQSSTPFDSPLSSRFDENDAILVLDNVFVPWENVLV---YGPAHKPIDFLMDTGYLQGTC 310
Query: 295 YGGC-KVGVG-DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQ 352
+ GC + V D L G A + + E+I L ++ A +
Sbjct: 311 FHGCTRFAVKLDFLAGLLTRALHITSGDEFRGNQVLQGEVIALRHLFWSLSDAMARTPEA 370
Query: 353 MKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPEIGPIVKK 411
++ L A + + + + I ++ +PS +DF++PEI +++
Sbjct: 371 FADSAFLPGLSAAQAYRALAPDAYGRVKEIVQKIVASALIYLPSSAKDFQNPEIDGYLER 430
Query: 412 YLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQAQRIMIARQGDLEGKK 471
Y+ G+ G ++R+++++L+ + T A + + AG+ + ++ + +G
Sbjct: 431 YVRGSNGVGYKDRIKLMKLLWDATGSEFAGRHELYERNYAGNHEEVKLQLPAIAKRDG-- 488
Query: 472 KLARAIAHIDESLD 485
+ + ++ +D+ LD
Sbjct: 489 SMDQMLSLVDQCLD 502
>gi|24115573|ref|NP_710083.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Shigella
flexneri 2a str. 301]
gi|24054905|gb|AAN45790.1| 4-hydroxyphenylacetate 3-monooxygenase large chain [Shigella
flexneri 2a str. 301]
Length = 350
Score = 74.3 bits (181), Expect = 2e-11, Method: Composition-based stats.
Identities = 75/330 (22%), Positives = 144/330 (43%), Gaps = 16/330 (4%)
Query: 166 DLYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLI-MPTIAMREADADYAVSFAVPSDAEG 224
D+Y+ + + + GI+VSGAK T + +H ++I + + + D+A+ F P DA+G
Sbjct: 3 DVYIKLEKETDAGIIVSGAKVVATNSALTHYNMIGFGSAQVMGENPDFALMFVAPMDADG 62
Query: 225 VIMIYGRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFM------CKEY 277
V +I R S + G+ D +S F ++A++V D V +P E V + C+ +
Sbjct: 63 VKLI-SRASYEMVAGATGSPYDYPLSSRFDENDAILVMDNVLIPWENVLIYRDFDRCRRW 121
Query: 278 QFAGMMVERFAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNE 337
G Y Q+ V + D + + + G + ++ L E++
Sbjct: 122 TMEGGFARM---YPLQACVRLAVKL-DFITALLKKSLECTGTLEFRGVQADLGEVVAWRN 177
Query: 338 TLYACGIACSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAE-DIAGGLMVTMPS 396
T +A + SE T G Y+ D + +I + E ++ GL+ S
Sbjct: 178 TFWALSDSMCSEATPWVNGAYLPDHAALQTYRVLAPMAYAKIKNIIERNVTSGLIYLPSS 237
Query: 397 QQDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGTAAVGYRTESMHGAGSPQA 456
+D +P+I + KY+ G+ G R+++L+L+ + + ++ +GS
Sbjct: 238 ARDLNNPQIDQYLAKYVRGSNGMDHVQRIKILKLMWDAIGSEFGGRHELYEINYSGSQDE 297
Query: 457 QRIMIARQGDLEGKKKLARAIAHIDESLDK 486
R+ RQ G + + +A +D L +
Sbjct: 298 IRLQCLRQAQSSG--NMDKMMAMVDRCLSE 325
>gi|28377032|ref|NP_783924.1| 4-hydroxyphenylacetate-3-hydroxylase [Lactobacillus plantarum
WCFS1]
gi|28269863|emb|CAD62760.1| 4-hydroxyphenylacetate-3-hydroxylase [Lactobacillus plantarum
WCFS1]
Length = 415
Score = 70.9 bits (172), Expect = 2e-10, Method: Composition-based stats.
Identities = 103/423 (24%), Positives = 179/423 (42%), Gaps = 29/423 (6%)
Query: 76 QSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQALGTTYHKRFI---- 131
++ DL+ K + + + Q + R D N + E LG + F
Sbjct: 3 RTVADLQQKHRAYQEIAQSNSGMLGRTP--DFLNTGMAVLAERAAFLGQNQYTDFAANAR 60
Query: 132 EYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLY--LHIVEVREDGIVVSGAKAHQT 189
Y K V+ ND+ + A+ +P+ +R + A P Y +H +E +DGI VSGAK T
Sbjct: 61 NYAKEVKANDIFISHALQNPQLNR--QKAINAIPSGYAGVHTIERNQDGIFVSGAKMVNT 118
Query: 190 GAVNSHEHLIM--PTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADIDL 247
A + + LI P + + D+ YAV+FA P + GV +I R+ D D L
Sbjct: 119 MAPIADDLLIFNPPELLLENGDSSYAVAFATPLNNPGVKIIC-RKLLD-HPTASITDYPL 176
Query: 248 GNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFAGYHRQSYGGCKVGVGDVLI 307
N+ +A +VFD F+P +VF+ + + + S+ G+ + +
Sbjct: 177 SNA-LDEIDAYIVFDHAFIPWSKVFVENNVEMSNRFFIDSGMFSHTSHQDEVRGITKLEL 235
Query: 308 GAAALA---ADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSEGTQMKAGNYMIDLLL 364
A +LA A G+ +++KL + E + G + G Y +L
Sbjct: 236 -ATSLALRIAHILGLDGFLGVQEKLGRLTANLELIKGTITRSEDNGHLDEFGIYTPNLQA 294
Query: 365 ANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGPIVKKYLAGATGKST-EN 423
+ + E R+ + +A G MV +PS +F + I+ + L T ++T +
Sbjct: 295 LQAVRSTLPEYYDEALRVTQHLAAGSMVGVPSFAEF-DGDNATILNQAL--TTDRATAKT 351
Query: 424 RMRVLRLIENITLGTAAVGYRT---ESMHGAGSPQAQRIMIARQGDLEGKKKLARAIAHI 480
R R+L L ++T ++ G R E HG G P R ++ DL+ ++ +
Sbjct: 352 RTRLLNLAFDLT--SSGFGQRQLMYEYYHG-GDPMRIRAQHYQRADLQAGNQMIDRLLSA 408
Query: 481 DES 483
D +
Sbjct: 409 DNA 411
>gi|154252236|ref|YP_001413060.1| 4-hydroxyphenylacetate 3-hydroxylase [Parvibaculum lavamentivorans
DS-1]
gi|154156186|gb|ABS63403.1| 4-hydroxyphenylacetate 3-hydroxylase [Parvibaculum lavamentivorans
DS-1]
Length = 493
Score = 70.5 bits (171), Expect = 2e-10, Method: Composition-based stats.
Identities = 105/455 (23%), Positives = 179/455 (39%), Gaps = 36/455 (7%)
Query: 3 TSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTATSN 62
T Q++E L++ +++ +IE+ D P + VA Y L + LM
Sbjct: 5 TGAQFLEGLKQPR-EIWVGDRKIESVADDPAFAGAARGVAAVYDLQHKEADACLMPDPE- 62
Query: 63 LTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGM-----DAFNAIYSTTYE 117
TG+++N + +S +DL +R G + + + VG+ D N Y+
Sbjct: 63 -TGEKINVSHMIPRSRQDLA-----RRRAGLEKIAAYS--VGLMGRTPDYMNVTYAGFAG 114
Query: 118 MDQALGTTYHKR----FIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVE 173
+ ++ + Y KY++ ND+ + + +P D+ + Q D+ L V
Sbjct: 115 RAEEWAVNGNEEGAENLVNYQKYLRRNDISLTHTIVNPTIDKAQGDAPQPGNDVALRKVG 174
Query: 174 VREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQS 233
E GIVV GA+ T A + E + P+ + +YA+SF +P G+ I
Sbjct: 175 ETEHGIVVRGARILATLAPFADEIAVYPSHPLPPDCDEYAISFCIPMSTPGLKFI----- 229
Query: 234 CDTRKMEEGADIDLGNS-EFGGHEALVVFDRVFVPNERVFM-CKEYQFAGMMVERFAGYH 291
C E D S F +A V+FD V VP R+ + C + +M+ +
Sbjct: 230 CRDSFSESSNFFDHPISGRFDEQDAFVIFDNVEVPRNRLHVNCNTAVYNSVMMRSWWPNV 289
Query: 292 RQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMI----HLNETLYACGIACS 347
Q V L A LA+ V + +K + EM+ E AC A
Sbjct: 290 MQQ---TTVRALTKLEFAWGLASRMTEV--INDVKPQTWEMLGEIWSYAELTRACLKAAE 344
Query: 348 SEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEIGP 407
G ++ D + ++ R ++ + + I + PS+ + P
Sbjct: 345 DGAIDYGNGVWLPDAQPFAALRASMPRWMARVSEIIQLIGSHNVFAAPSRAQLDDAGLRP 404
Query: 408 IVKKYLAGATGKSTENRMRVLRLIENITLGTAAVG 442
++ YL GA E R RV RL + +GT G
Sbjct: 405 LIDHYLRGAGDVGAEQRARVFRLAWDF-VGTGLAG 438
>gi|16078922|ref|NP_389743.1| hypothetical protein BSU18620 [Bacillus subtilis subsp. subtilis
str. 168]
gi|2618997|gb|AAB84421.1| transcription antiterminator [Bacillus subtilis]
gi|2634255|emb|CAB13754.1| yoaI [Bacillus subtilis subsp. subtilis str. 168]
Length = 375
Score = 70.1 bits (170), Expect = 3e-10, Method: Composition-based stats.
Identities = 79/341 (23%), Positives = 152/341 (44%), Gaps = 19/341 (5%)
Query: 105 MDAFNAIYSTTYEMDQALGTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQAD 164
M+ ++++ E+ + + + ++ + +DL P+ +R S ++
Sbjct: 1 MNTVMMSFASSAELLKDKENCFPEHILDMYEQAAKHDLSFTHTFITPQVNRSQSYFGLSE 60
Query: 165 PDLYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEG 224
+ +++ E G+++ GA+ T + E L+ + D A +F++PS+ +G
Sbjct: 61 KPISAKVIDRTEKGLMIHGARLLATQGGLTDEILVFSAPKFF-FETDEAYAFSIPSNTKG 119
Query: 225 VIMIYGRQSCDTRKMEEGADIDLG---NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAG 281
V I TR+ +D +S + +++VVFD V VP RVF + A
Sbjct: 120 VKFI-------TRESFVLSDSSFNHPLSSRYEEMDSIVVFDHVLVPWNRVFFYDNVEAAK 172
Query: 282 MMVERFAGYHRQSYGGCKVGVG---DVLIGAAALAADYNGVPKASHIKDKLIEMIHLNET 338
+ + + +H ++ + + L+G A L D V + HI++KL E+I ET
Sbjct: 173 DFMTK-SSFHAFTFHQVVIRQMIKIEFLLGVAQLLVDTINVSEYQHIQEKLSEIIVGLET 231
Query: 339 LYACGIACSSEGTQMKAGNYMIDLLLA-NVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ 397
+ A I S Q+ YM L+ V I +L + + I MVT+P++
Sbjct: 232 IKAL-IDKSENDAQLDEFGYMRPCLIPLQVISTIIPKLYPRFTEIIQLIGASGMVTLPTE 290
Query: 398 QDFRHPEIGPIVKKYLAGATGKSTENRMRVLRLIENITLGT 438
F EI + +YL AT + E R+++ RL ++T+ +
Sbjct: 291 NAF-DSEIREDLDQYLQ-ATNTNAEERVKIFRLAWDLTMSS 329
>gi|50428396|dbj|BAD30042.1| oxygenase component of 4-NP monooxygenase [Rhodococcus opacus]
Length = 528
Score = 65.9 bits (159), Expect = 6e-09, Method: Composition-based stats.
Identities = 109/451 (24%), Positives = 186/451 (41%), Gaps = 40/451 (8%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
M T +QY+ESLR +VY GE I++ HP ++A Y L E++ ++T
Sbjct: 1 MRTGQQYLESLRD-GRQVYVGGELIDDVTTHPKTSGYAKAIAEYYDLHLDPEHQDVLTFV 59
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEM-- 118
+ G + + L +S D + + FQ + ++ Y
Sbjct: 60 DD-DGVRKSMHWFLPRSKADAARRRAYHEFWFRH----FQGGIFTRPPAGMHVVMYAQID 114
Query: 119 ------DQAL-----GTTYHKRFIEYMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDL 167
D A+ ++ + V +D+ + D + DRG + P
Sbjct: 115 DPEPWGDNAVVAGGRTISFADNIRSQWQRVTTDDVALSPMFVDVQFDRGRDDALVETP-- 172
Query: 168 YLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIM 227
L IVE + GIVV G KA T +E L++ + +D V VP + G+ +
Sbjct: 173 MLSIVEQNDQGIVVRGWKAMGTSLPFVNE-LLVGNLWRPGQTSDQTVYAIVPVNTPGLSL 231
Query: 228 IYGRQSCDTRKMEEGADIDLGNSEFGGH-EALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
+ RQS T + D S G + + FD VF+P E V A +R
Sbjct: 232 VC-RQSNAT---PDADPYDHPLSTIGDELDGMAYFDDVFIPWENVQHIGNPDHAKWYPQR 287
Query: 287 -FAGYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
F H ++ V ++++G A L + G ++ +L +++ ET A IA
Sbjct: 288 QFDWVHIETQIRHAVH-AELIVGLALLLTNALGTNNNPIVQSQLADLVRFRETCKAFAIA 346
Query: 346 C-----SSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDF 400
++ G K N +DL A+ +NI + +L E G++++ P++ DF
Sbjct: 347 AEETGFTTAGGLFKPNNIYVDLGRAHYL-ENIHN---AVNQLIEFCGRGVVMS-PTKADF 401
Query: 401 RHPEIGPIVKKYLAGATGKSTENRMRVLRLI 431
HP +GP +++ L G T S +R+ + R I
Sbjct: 402 DHPFLGPKLEEALRG-TSISARDRVSIFRQI 431
>gi|154684732|ref|YP_001419893.1| YoaI [Bacillus amyloliquefaciens FZB42]
gi|154350583|gb|ABS72662.1| YoaI [Bacillus amyloliquefaciens FZB42]
Length = 373
Score = 64.7 bits (156), Expect = 1e-08, Method: Composition-based stats.
Identities = 75/272 (27%), Positives = 129/272 (47%), Gaps = 17/272 (6%)
Query: 171 IVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYG 230
+V+ E G+++ GA+ T + E L++ M ++D A +F++PS+ +GV I
Sbjct: 67 VVDKNEKGLIIHGARILATQGGLTDEVLVVSLPKMY-FESDEAFAFSIPSNTKGVKFIC- 124
Query: 231 RQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQ--FAGMMVERFA 288
R+S K D L +S + +++VVFD V VP ERVF Y+ F M F
Sbjct: 125 RESFVLGK--SSFDYPL-SSRYEEMDSIVVFDHVLVPWERVFFYNNYEAAFDFNMKSSFN 181
Query: 289 GYHRQSYGGCKVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSS 348
+ ++ + L+G A + V + HI+ K+ E+I ET+ A + S
Sbjct: 182 AFAFHQVITRQIVKTEFLLGLAQTLVEAIDVGEYQHIQAKMAEIITGLETMKAL-LEKSE 240
Query: 349 EGTQMKAGNYM----IDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPE 404
+ YM L + + +I EI +L I MVT+P+++ FR +
Sbjct: 241 NDAETDEWGYMRPSVTPLRVVSAIFPDIYPRFTEIIQL---IGASGMVTLPTEKAFR-SD 296
Query: 405 IGPIVKKYLAGATGKSTENRMRVLRLIENITL 436
I + +YL A + E+R++V RL ++T+
Sbjct: 297 IRGDLDQYLQAAE-LNAEDRVKVFRLAWDLTM 327
>gi|120404135|ref|YP_953964.1| 4-hydroxyphenylacetate 3-hydroxylase [Mycobacterium vanbaalenii
PYR-1]
gi|119956953|gb|ABM13958.1| 4-hydroxyphenylacetate 3-hydroxylase [Mycobacterium vanbaalenii
PYR-1]
Length = 471
Score = 63.9 bits (154), Expect = 2e-08, Method: Composition-based stats.
Identities = 76/285 (26%), Positives = 117/285 (41%), Gaps = 31/285 (10%)
Query: 133 YMKYVQDNDLVVDGAMTDPKGDRGLSPSEQADPDLYLHIVEVREDGIVVSGAKAHQTGAV 192
Y +Y + L V ++ P+ + P+ + P + +VE +GIVV GA+ TGA
Sbjct: 127 YHRYAAERGLWVTNSIVPPQANPN-DPTSRVRP---VRLVEETAEGIVVDGAQMLGTGAA 182
Query: 193 NSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIYGRQSCDTRKMEEGADIDLG-NSE 251
+ + + + D AVSF VP A G+ ++ C G D ++
Sbjct: 183 VADAIFVTSIRPLAPDETDRAVSFVVPISAPGLKLL-----CRRPYATAGEPFDYPLSTR 237
Query: 252 FGGHEALVVFDRVFVPNERVFMCKEY-----QFAGMMVERFAGYHRQSYGGCKVGVGDVL 306
F +A+VVFDRV VP VF + QF G + K+ +
Sbjct: 238 FDETDAMVVFDRVLVPWSSVFAAGDVTVVNSQFFGTAAHQIGNLQSIIRLTAKL---RFV 294
Query: 307 IGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIACSSE------GTQMKAGNYMI 360
G A+L NG IK +L E+ + A A S G AG Y
Sbjct: 295 TGVASLIVKANGRDTDPAIKGQLAELATVQTVSEALTHAAHSHAERDEYGVYRPAGKY-- 352
Query: 361 DLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQ-QDFRHPE 404
L A + Q T + + +L ++AGG ++ +PS +DF PE
Sbjct: 353 --LYAALGMQ--TEVYPKAIKLLGELAGGGVIQVPSSVRDFDDPE 393
>gi|89096535|ref|ZP_01169427.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus sp. NRRL B-14911]
gi|89088550|gb|EAR67659.1| 4-hydroxyphenylacetate-3-hydroxylase [Bacillus sp. NRRL B-14911]
Length = 491
Score = 63.9 bits (154), Expect = 3e-08, Method: Composition-based stats.
Identities = 98/451 (21%), Positives = 190/451 (42%), Gaps = 43/451 (9%)
Query: 5 EQYVESLRKLNLKVYFMGERIENPV-DHPMIRPSMNSVAMTY------KLAEMDEYKHLM 57
++++E L + +V+ GER+ + +HP + + + A Y +L E E +
Sbjct: 17 KEFIERLDLMENEVWLDGERVAGKISEHPAFKGIVTAKASLYDKQCDPQLQE--ELTFRI 74
Query: 58 TATSNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYE 117
T+ L G R Q+ EDL + KM T GM + Y T
Sbjct: 75 PGTAELAGLSYLR----PQTKEDLLKRRKMTEHWAMSTH-------GMMGRSPDYMNTAV 123
Query: 118 MD-QALGTTYHKRFIEYMKYVQ-------DNDLVVDGAMTDPKGDRGLSPSEQADPDLYL 169
M A + R + +VQ DL + P+ +R + +D +
Sbjct: 124 MSLAASASVLAGRENCFPGHVQALYERAIHEDLSFTHTLITPQVNRS-AFYLGSDTPISA 182
Query: 170 HIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVIMIY 229
+VE +G+V+ GA+ T + E L++ + D + A +F++PS+ +G+ I
Sbjct: 183 KVVEKNHNGLVIKGARLLATQGGLTDELLVLSSPG--RFDTEEAFAFSIPSNTDGLRFI- 239
Query: 230 GRQSCDTRKMEEGADIDLG-NSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVERFA 288
C +G+ D +S + +A+VVFD V VP ERVF+ + A + + +
Sbjct: 240 ----CRGSFAGDGSAFDYPLSSHYDEMDAIVVFDDVLVPWERVFLYDNVE-AALAFKNKS 294
Query: 289 GYHRQSYGGC---KVGVGDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
+H +Y ++ + ++G A V + HI+ K+ E+I E++ A
Sbjct: 295 SFHSFAYHQALIRQIVKTEFILGIAESIVKCLNVSEYQHIQAKMAEIIIGLESMKALLEK 354
Query: 346 CSSEGTQMKAGNYMIDLLLANVCKQNITRLPYEIARLAEDIAGGLMVTMPSQQDFRHPEI 405
++ + G ++ + L + + I + ++P+++DF I
Sbjct: 355 SENDAIPDEFGCMRPSIVPLQIASNLFPELYPRFCEIIQVIGASGLTSLPTEKDF-ESGI 413
Query: 406 GPIVKKYLAGATGKSTENRMRVLRLIENITL 436
+ +YL A G + + R+++ RL ++T+
Sbjct: 414 RADLDQYLQ-AEGLNAKERVQLFRLAWDLTM 443
>gi|5295892|emb|CAB46018.1| hypothetical protein [Porphyromonas gingivalis]
Length = 27
Score = 62.0 bits (149), Expect = 9e-08, Method: Composition-based stats.
Identities = 25/27 (92%), Positives = 27/27 (100%)
Query: 264 VFVPNERVFMCKEYQFAGMMVERFAGY 290
+F+PNERVFMCKEYQFAGMMVERFAGY
Sbjct: 1 LFLPNERVFMCKEYQFAGMMVERFAGY 27
>gi|10443727|gb|AAG17551.1|AF230879_1 putative phenazine hydroxylase PhzO [Pseudomonas chlororaphis]
Length = 491
Score = 61.2 bits (147), Expect = 2e-07, Method: Composition-based stats.
Identities = 88/375 (23%), Positives = 150/375 (40%), Gaps = 33/375 (8%)
Query: 1 MMTSEQYVESLRKLNLKVYFMGERIENPVDHPMIRPSMNSVAMTYKLAEMDEYKHLMTAT 60
+ ++E + SLR N V + G+ +E+ H ++ VA Y+ E+ ++T
Sbjct: 11 LKSAESFKASLRD-NRTVIYQGQVVEDVTTHFSTAGGISQVAEIYEEQFSGEHDDILTYV 69
Query: 61 SNLTGKQVNRFCHLHQSTEDLKDKVKMQRLMGQKTASCFQRCVGMDAFNAIYSTTYEMDQ 120
G + ++ EDL + + + QKT R + M I S T M
Sbjct: 70 RP-DGYLASSAYMPPRNKEDLASRRRAIMYVSQKTWGTHCRNLDM-----IASFTVGMMG 123
Query: 121 ALGT------TYHKRFIEYMKYVQDNDLVVDGAMTDPKG--------DRGLSPSEQADPD 166
L T Y + EY Y + N L + + DP+G D L P ++A
Sbjct: 124 YLPTFRKKCPEYAENITEYHDYAERNSLYLSETIVDPQGYRARTHGTDLNLPPPDRA--- 180
Query: 167 LYLHIVEVREDGIVVSGAKAHQTGAVNSHEHLIMPTIAMREADADYAVSFAVPSDAEGVI 226
+ I + +GI +SG K T A S+E + ++ +A VP DA GV
Sbjct: 181 -VMRINKQNAEGIWISGVKGVGTAAPQSNEIFVGSLFPAAPEESFWAY---VPVDAPGV- 235
Query: 227 MIYGRQSCDTRKMEEGADIDLGNSEFGGHEALVVFDRVFVPNERVFMCKEYQFAGMMVER 286
I+ R+ + E EA+VVFD VF+P R+ + A
Sbjct: 236 KIFCREIVSQPHASAYDHPLISKGEEA--EAMVVFDNVFIPRWRIMAANVPELASAGFFS 293
Query: 287 FAGYHRQSYGGCKVGV-GDVLIGAAALAADYNGVPKASHIKDKLIEMIHLNETLYACGIA 345
+ Y ++ D+ G A + + G+ + ++ ++ E++ L E L IA
Sbjct: 294 LWTSYSHWYTLVRLETKADLYAGLAKVIMEVLGLEGIAVVRQRVSEIVQLAEILKGMCIA 353
Query: 346 CSSEGTQMKAGNYMI 360
S E +M G+ ++
Sbjct: 354 -SIETAEMSDGDILL 367
Database: nr
Posted date: Sep 17, 2007 11:41 AM
Number of letters in database: 999,999,834
Number of sequences in database: 2,976,859
Database: /nucleus1/users/jsaw/ncbi/db/nr.01
Posted date: Sep 17, 2007 11:48 AM
Number of letters in database: 894,087,890
Number of sequences in database: 2,493,262
Lambda K H
0.319 0.134 0.387
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 1,725,165,736
Number of Sequences: 5470121
Number of extensions: 72353780
Number of successful extensions: 153322
Number of sequences better than 1.0e-05: 169
Number of HSP's better than 0.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 152793
Number of HSP's gapped (non-prelim): 182
length of query: 486
length of database: 1,894,087,724
effective HSP length: 137
effective length of query: 349
effective length of database: 1,144,681,147
effective search space: 399493720303
effective search space used: 399493720303
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 132 (55.5 bits)