Tiny Conspiracies: Cell-to-Cell Communication in Bacteria |
|
|---|---|
|
|
|
| Launch in standalone player | |
| Air date: | Wednesday, March 10, 2004, 3:00:00 PM |
| Category: | Wednesday Afternoon Lectures |
| Description: | Quorum sensing, or the control of gene expression in response to cell density, is used by bacteria to regulate a variety of physiological functions. Quorum sensing bacteria produce, release and detect extracellular signalling molecules called autoinducers that accumulate in the environment as the cell population increases. In the bioluminescent marine bacterium V. harveyi, two parallel quorum sensing systems exist and function to control light production. System 1 is composed of Sensor 1 and Autoinducer-1 (AI-1), and System 2 is composed of Sensor 2 and Autoinducer-2 (AI-2). Our results suggest that V. harveyi uses AI-1 for intra-species communication and AI-2 for inter-species cell-cell signalling.
The NIH Director's Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. |
| Author: | Bonnie Bassler, Ph.D., Princeton University |
| Runtime: | 60 minutes |
| Rights: | This is a work of the United States Government. No copyright exists on this material. It may be disseminated freely. |
| Download: | Download
Video How to download a Videocast |
| CIT File ID: | 11868 |
| CIT Live ID: | 2617 |
| Permanent link: | http://videocast.nih.gov/launch.asp?11868 |