|
Mechanism of action
|
Drug
|
NSC No.
|
ME:LOXIMVI
|
ME:MALME-3M
|
ME:SK-MEL-2
|
ME:SK-MEL-5
|
ME:SK-MEL-28
|
LC:NCI-H23
|
ME:M14
|
ME:UACC-62
|
LC:NCI-H522
|
LC:A549/ATCC
|
LC:EKVX
|
LC:NCI-H322M
|
LC:NCI-H460
|
LC:HOP-62
|
LC:HOP-92
|
CNS:SNB-19
|
CNS:SNB-75
|
CNS:U251
|
CNS:SF-268
|
CNS:SF-295
|
CNS:SF-539
|
CO:HT29
|
CO:HCC-2998
|
CO:HCT-116
|
CO:SW-620
|
CO:HCT-15
|
CO:KM12
|
OV:OVCAR-3
|
OV:OVCAR-4
|
OV:OVCAR-8
|
OV:IGROV1
|
OV:SK-OV-3
|
LE:CCRF-CEM
|
LE:K-562
|
LE:MOLT-4
|
LE:SR
|
RE:UO-31
|
RE:SN12C
|
RE:A498
|
RE:CAKI-1
|
RE:RXF-393
|
RE:786-0
|
RE:ACHN
|
RE:TK-10
|
ME:UACC-257
|
LC:NCI-H226
|
CO:COLO205
|
OV:OVCAR-5
|
LE:HL-60
|
LE:RPMI-8226
|
BR:MCF7
|
BR:MCF7/ADF-RES
|
PR:PC-3
|
PR:DU-145
|
BR:MDA-MB-231/ATCC
|
BR:HS578T
|
BR:MDA-MB-435
|
BR:MDA-N
|
BR:BT-549
|
BR:T-47D
|
| A2 | Mitomycin | 26980 | 6.54285 | 6.07549 | 5.77834 | 6.43813 | 5.72194 | 6.90796 | 6.40159 | 6.92035 | 6.17722 | 6.70863 | 5.26081 | 5.99069 | 7.75413 | 6.97018 | 5.40171 | 6.48873 | 6.37268 | 6.44383 | 6.27943 | 6.81383 | 6.65397 | 6.10118 | 6.15206 | 6.15323 | 6.30988 | 5.86996 | 5.5855 | 5.44192 | 5.43416 | 5.91205 | 5.4921 | 6.01668 | 6.64888 | 5.68723 | 6.62435 | 6.90543 | 5.61546 | 6.62222 | 6.14637 | 6.55416 | 5.58242 | 6.35124 | 6.82955 | 5.29437 | 5.83195 | 6.13349 | 5.94757 | 5.8314 | 6.7195 | 5.52515 | 6.71785 | 5.22548 | 5.54335 | 6.72576 | 5.07043 | 5.45696 | 5.66494 | 5.6831 | 5.61388 | 5.65978 |
| A2 | Porfiromycin | 56410 | 5.81754 | 5.33731 | 4.85471 | 5.70779 | 4.86128 | 6.05217 | 6.18206 | 6.2239 | 5.14923 | 6.34561 | 4.66881 | 5.1687 | 7 | 6.44116 | 4.86436 | 5.61831 | 5.80833 | 5.82612 | 5.30095 | 6.28128 | 5.46823 | 5.46577 | 5.46312 | 5.45365 | 5.53024 | 5.25995 | 4.85328 | 5.0294 | 4.94665 | 5.15494 | 4.93901 | 4.9955 | 5.70109 | 4.77805 | 6.16626 | 6.63448 | 4.76919 | 6.06083 | 5.24486 | 5.73578 | 4.93298 | 5.75122 | 6.32652 | 4.87799 | 4.97921 | 5.08703 | 5.31908 | 4.99265 | 6.13311 | 5.08124 | 6.15684 | 4.51405 | 4.95101 | 6.59109 | 4.39248 | 4.75949 | 4.88399 | 4.90539 | 4.91453 | 5.03553 |
| A6 | Carmustine (BCNU) | 409962 | 4.40145 | 4.0578 | 4.07482 | 4.09851 | 4.07481 | 4.0603 | 4.11591 | 4.6864 | 4.21775 | 3.99513 | 3.97080 | 3.77866 | 4.24084 | 4.0019 | 4.15819 | 4.18994 | 4.22387 | 4.26858 | 4.39397 | 4.3206 | 4.30183 | 4.07172 | 4.01208 | 4.1372 | 4.2472 | 4.16650 | 4.06488 | 4.05267 | 4.06825 | 4.07569 | 4.12035 | 3.97008 | 4.75662 | 4.33787 | 4.51698 | 4.82159 | 3.99160 | 4.11791 | 3.96246 | 4.13681 | 4.10409 | 4.40529 | 4.08663 | 4.04157 | 4.09841 | 4.00409 | 4.12606 | 3.99212 | 4.84267 | 4.24068 | 4.07802 | 4.02138 | 3.9817 | 3.69171 | 4.03743 | 3.9835 | 4.07794 | 4.09326 | 4.09307 | 3.93558 |
| A6 | Chlorozotocin | 178248 | 4.02047 | 3.24679 | 3.09793 | 3.12388 | 2.90309 | 2.91706 | 3.09037 | 4.29072 | 2.90309 | 2.92216 | 2.90309 | 2.90309 | 3.51687 | 3.41585 | 3.49363 | 3.61027 | 3.45249 | 3.77956 | 3.97849 | 4.00879 | 4.04707 | 2.90309 | 2.90309 | 3.11997 | 2.95962 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 3.42919 | 3.31513 | 3.96728 | 3.28717 | 2.90309 | 3.01852 | 2.90309 | 3.13041 | 2.90309 | 4.23126 | 3.46455 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 3.57727 | 2.90309 | 2.90309 | 2.90309 | 2.90309 | 3.26424 | 2.90309 | 2.90309 | 3.09018 | 3.47524 | 3.39559 | 3.21985 |
| A6 | Clomesone | 338947 | 4.32955 | 3.33044 | 3.2961 | 3.65128 | 3.30692 | 3.86037 | 3.69275 | 4.48888 | 3.67143 | 3.59814 | 3.47086 | 3.2774 | 4.01329 | 3.80728 | 3.836 | 3.93708 | 4.04251 | 4.13982 | 4.18371 | 4.34411 | 4.23931 | 3.33335 | 3.55072 | 3.75908 | 3.82384 | 3.697 | 3.57656 | 3.65370 | 3.38344 | 3.47239 | 3.36817 | 3.32416 | 3.89611 | 3.74956 | 4.02040 | 5.23725 | 3.26294 | 3.66048 | 3.27077 | 3.67863 | 3.82243 | 4.25927 | 3.82353 | 3.24965 | 3.80765 | 3.4757 | 3.29994 | 3.15418 | 4.02872 | 3.83902 | 3.70543 | 3.59003 | 3.33444 | 3.68151 | 3.49964 | 3.69185 | 3.00395 | 3.98783 | 4.00233 | 3.67479 |
| A6 | Lomustine (CCNU) | 79037 | 4.99879 | 4.1155 | 4.09856 | 4.19847 | 4.14139 | 4.13882 | 4.22347 | 4.85028 | 4.5228 | 4.23157 | 4.03312 | 4.09061 | 4.49644 | 4.08825 | 4.28410 | 4.2431 | 4.39877 | 4.44135 | 4.61539 | 4.47376 | 4.6618 | 4.21249 | 4.11322 | 4.36655 | 4.46376 | 4.52626 | 4.12593 | 4.12501 | 4.13576 | 4.21498 | 4.19097 | 4.05458 | 4.85815 | 4.64631 | 4.71651 | 5.01316 | 4.08089 | 4.28079 | 4.09938 | 4.32471 | 4.18973 | 4.56131 | 4.16597 | 4.11268 | 4.16329 | 4.17487 | 4.18992 | 4.04294 | 4.80955 | 4.75011 | 4.29629 | 4.22503 | 4.16718 | 4.12049 | 4.30405 | 3.92932 | 5.20372 | 4.24951 | 5.27857 | 4.44571 |
| A6 | Mitozolamide | 353451 | 4.73111 | 3.74116 | 3.56866 | 3.77366 | 3.61565 | 3.79353 | 3.69306 | 4.60519 | 3.79552 | 3.76463 | 3.56178 | 3.73257 | 4.32452 | 4.26041 | 3.85334 | 3.98081 | 4.34058 | 4.33093 | 4.46766 | 4.50993 | 4.4291 | 3.81196 | 3.79928 | 3.89396 | 3.79093 | 3.72020 | 3.80173 | 3.72596 | 3.82531 | 3.81631 | 3.68599 | 3.8009 | 4.33174 | 4.12845 | 4.47996 | 4.19436 | 3.65137 | 3.94681 | 3.69785 | 3.9211 | 3.78677 | 4.49184 | 4.27474 | 3.65889 | 3.77257 | 3.72577 | 3.77179 | 3.55614 | 4.43563 | 3.77523 | 3.87884 | 3.78251 | 3.75687 | 3.99778 | 3.65897 | 3.62160 | 3.76498 | 3.85414 | 3.99801 | 3.60299 |
| A6 | PCNU | 95466 | 4.33081 | 3.64687 | 3.57881 | 3.67647 | 3.40596 | 3.57831 | 3.50666 | 4.77911 | 3.63440 | 3.81766 | 2.90309 | 3.25923 | 4.09355 | 3.80423 | 3.62698 | 3.95497 | 4.12641 | 4.27169 | 4.37035 | 4.65021 | 4.29309 | 3.13397 | 3.14472 | 3.69978 | 3.78643 | 3.52329 | 3.56408 | 3.03849 | 2.90309 | 4.15788 | 3.50421 | 3.19317 | 4.04538 | 3.65922 | 4.23779 | 4.9526 | 3.12418 | 3.64734 | 3.65588 | 3.56692 | 3.61643 | 4.22336 | 3.33637 | 3.36719 | 3.46084 | 3.35623 | 3.60515 | 3.03985 | 4.12834 | 3.67489 | 3.46447 | 3.57617 | 2.99223 | 3.45534 | 3.51376 | 3.48949 | 3.71222 | 3.62613 | 3.63048 | 3.59435 |
| A6 | Semustine (MeCCNU) | 95441 | 4.70923 | 4.34633 | 4.331 | 4.39817 | 4.34495 | 4.27410 | 4.39454 | 4.96936 | 4.32937 | 4.21672 | 4.09272 | 3.94134 | 4.41195 | 4.24138 | 4.40833 | 4.43885 | 4.41488 | 4.51967 | 4.575 | 4.56525 | 4.55002 | 4.26914 | 4.3448 | 4.38694 | 4.49374 | 4.35031 | 4.25527 | 4.35866 | 4.33397 | 4.31126 | 4.40211 | 4.03334 | 4.59333 | 4.352 | 4.46685 | 4.97634 | 4.28483 | 4.36018 | 4.25634 | 4.34071 | 4.36948 | 4.50691 | 4.31397 | 4.22531 | 4.32669 | 4.19955 | 4.34431 | 4.23392 | 4.38598 | 4.43635 | 4.34616 | 4.30776 | 4.33332 | 4.01021 | 4.30345 | 4.22446 | 4.43067 | 4.34603 | 4.3441 | 4.3144 |
| A7 | Asaley | 167780 | 5.58875 | 5.59863 | 5.60337 | 5.46394 | 5.22577 | 5.35069 | 5.54795 | 5.75141 | 5.77378 | 4.83439 | 4.72548 | 4.66125 | 5.46533 | 5.26533 | 5.7995 | 4.86167 | 4.8975 | 5.11878 | 5.37966 | 5.18218 | 5.55292 | 4.76997 | 4.83524 | 4.7864 | 5.10449 | 4.99057 | 4.68642 | 5.38939 | 4.7542 | 5.08654 | 4.86254 | 4.7786 | 6.1655 | 5.29867 | 6.3916 | 5.97853 | 5.16444 | 5.4972 | 4.72911 | 6.006 | 5.67488 | 5.64394 | 5.60434 | 4.79285 | 5.44832 | 4.78924 | 5.45753 | 4.78529 | 6.43045 | 5.52674 | 5.36727 | 4.72165 | 4.7942 | 5.22155 | 5.18739 | 5.40930 | 5.47429 | 5.56995 | 5.26979 | 5.6445 |
| A7 | Busulfan | 750 | 5.22467 | 3 | 3 | 3.30068 | 3 | 3.12187 | 3.09487 | 3.36012 | 3.49494 | 3.27941 | 3 | 3 | 3.64013 | 3.26719 | 3.16013 | 3 | 3.38785 | 3.29419 | 3.36864 | 3.37927 | 3.32853 | 3 | 3 | 3.13238 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3.08828 | 3.56412 | 3.09112 | 3.84908 | 4.17631 | 3 | 3.13702 | 3 | 3.54028 | 3.16424 | 3.31946 | 3.45214 | 3 | 3.34224 | 3 | 3 | 3 | 3.67160 | 3.03689 | 3.33767 | 3 | 3 | 3.12019 | 3 | 3 | 3 | 3 | 3 | 3.21072 |
| A7 | Carboplatin | 241240 | 4.15379 | 4.13384 | 3.60206 | 3.9297 | 3.65134 | 4.19480 | 3.93966 | 4.36501 | 4.21979 | 3.95315 | 3.60206 | 3.60206 | 4.46972 | 3.80921 | 3.8471 | 3.75397 | 3.98431 | 4.17108 | 4.24976 | 4.17119 | 4.07922 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 4.21402 | 4.11085 | 3.60206 | 4.24698 | 3.60206 | 4.10206 | 3.60206 | 4.02451 | 4.19357 | 3.68784 | 3.7641 | 3.60206 | 4.03466 | 4.05232 | 4.01779 | 4.06251 | 3.60206 | 3.90592 | 3.95644 | 3.60206 | 3.60206 | 4.57016 | 3.60206 | 3.80814 | 3.63866 | 3.60206 | 3.82943 | 3.60206 | 3.90311 | 3.66874 | 3.64032 | 4.0081 | 3.60206 |
| A7 | Chlorambucil | 3088 | 4.39983 | 4.06868 | 3.82189 | 4.00932 | 3.94697 | 4.55338 | 4.2007 | 4.69095 | 4.60168 | 4.23883 | 3.75583 | 3.71598 | 4.79481 | 4.46141 | 4.02233 | 4.01741 | 4.15154 | 4.38379 | 4.48307 | 4.40190 | 4.67747 | 3.88206 | 3.94446 | 3.96494 | 4.03232 | 4.02214 | 3.86805 | 3.86679 | 3.85847 | 4.07602 | 3.89862 | 3.92312 | 5.22221 | 3.94444 | 5.31299 | 5.32211 | 4.11693 | 4.46474 | 3.8758 | 4.75566 | 4.54058 | 4.53202 | 4.80915 | 3.75167 | 3.96455 | 4.00002 | 3.92682 | 3.99425 | 5.17458 | 4.16386 | 4.44105 | 4.15110 | 3.99846 | 4.21055 | 3.79371 | 3.78546 | 3.93923 | 3.97327 | 3.98500 | 4.24797 |
| A7 | Cisplatin | 119875 | 5.75486 | 5.73754 | 5.07841 | 5.4124 | 5.13815 | 5.98138 | 5.55053 | 5.78458 | 5.52435 | 5.32778 | 4.94376 | 5.04005 | 6.11622 | 5.59331 | 5.28546 | 5.32508 | 5.50978 | 5.62449 | 6.05623 | 5.92509 | 5.71295 | 4.96339 | 5.1063 | 5.1906 | 5.20551 | 5.03838 | 4.90482 | 5.45923 | 5.76648 | 5.1967 | 5.65768 | 5.07786 | 5.81575 | 5.08895 | 5.77467 | 6.15103 | 5.24592 | 5.18793 | 5.00676 | 5.6295 | 5.26167 | 5.7323 | 5.70427 | 4.91054 | 5.19557 | 5.13826 | 4.84675 | 5.12379 | 6.29571 | 5.19095 | 5.47088 | 5.22787 | 5.17987 | 5.65766 | 4.74067 | 5.13424 | 5.15693 | 5.18072 | 5.20942 | 4.81084 |
| A7 | Cyclodisone | 348948 | 4.83864 | 4.21104 | 4.30074 | 4.41779 | 4.11037 | 4.38566 | 4.29948 | 4.9562 | 4.34883 | 4.42223 | 4.18922 | 4.11855 | 4.89378 | 4.46741 | 4.35589 | 4.46843 | 4.56995 | 4.66285 | 4.7812 | 4.92064 | 4.91429 | 4.23808 | 4.40087 | 4.43288 | 4.31555 | 4.30111 | 4.29366 | 4.33989 | 4.31996 | 4.2879 | 4.30817 | 4.16088 | 4.72706 | 4.20452 | 4.97777 | 4.31764 | 4.21989 | 4.30083 | 4.27191 | 4.39955 | 4.42738 | 4.87681 | 4.82105 | 4.06981 | 4.29644 | 4.32117 | 4.32921 | 4.10179 | 4.97297 | 4.36348 | 4.31613 | 4.27955 | 3.96934 | 4.29212 | 3.99445 | 4.21879 | 4.40532 | 4.45982 | 4.43786 | 4.27817 |
| A7 | Diaminocyclohexyl-Pt-II | 271674 | 5.54434 | 5.98983 | 4.71824 | 5.91555 | 5.40148 | 5.59878 | 5.29955 | 5.62653 | 5.61901 | 5.98385 | 4.72134 | 4.92303 | 6.27314 | 4.72493 | 4.87363 | 4.93812 | 4.83557 | 5.24711 | 5.40664 | 5.52122 | 5.43341 | 6.12514 | 5.09592 | 6.19868 | 6.37858 | 5.7657 | 5.16858 | 5.30818 | 5.35234 | 5.65059 | 5.39189 | 4.59046 | 6.01715 | 5.81734 | 6.35639 | 5.94335 | 5.15122 | 5.69465 | 4.90773 | 6.08628 | 5.25383 | 6.23367 | 6.21113 | 4.74796 | 5.04917 | 5.75522 | 5.7353 | 5.35249 | 6.07739 | 6.37134 | 5.78816 | 5.58403 | 5.52795 | 5.16152 | 4.77232 | 5.05948 | 6.01503 | 5.73918 | 4.93436 | 5.59635 |
| A7 | Dianhydrogalactitol | 132313 | 4.65496 | 4.08721 | 3.82391 | 4.21294 | 3.82391 | 4.63271 | 4.81604 | 4.97386 | 4.13314 | 4.64003 | 3.82391 | 3.82391 | 5.42022 | 4.77561 | 3.82391 | 4.04345 | 4.34864 | 4.47651 | 4.42548 | 4.87366 | 4.37016 | 3.82391 | 3.99671 | 4.25041 | 3.82391 | 4.00179 | 3.82391 | 3.88954 | 3.82391 | 4.06216 | 3.82391 | 4.13509 | 5.05458 | 3.89035 | 5.23086 | 5.71535 | 3.85332 | 4.61161 | 3.82391 | 4.67708 | 3.99219 | 5.10124 | 5.3469 | 3.99829 | 3.902 | 3.96636 | 3.82391 | 3.88108 | 5.2747 | 3.90269 | 4.90423 | 4.19363 | 4.38402 | 5.0299 | 3.84713 | 4.02884 | 4.33658 | 4.55111 | 4.52982 | 4.64602 |
| A7 | Diaziridinylbenzoquinone | 182986 | 5.60611 | 5.24965 | 5.20757 | 5.42889 | 4.86943 | 5.73808 | 5.59776 | 6.29253 | 5.45907 | 5.72817 | 5.22325 | 4.74165 | 6.79421 | 6.07567 | 5.29237 | 5.36316 | 5.35497 | 5.57458 | 5.53544 | 5.94859 | 5.82013 | 5.15437 | 5.17369 | 5.45364 | 5.34068 | 5.07794 | 5.03446 | 5.28963 | 5.31789 | 5.41142 | 5.24836 | 5.3016 | 5.90345 | 5.29893 | 5.83878 | 6.27073 | 5.26308 | 5.84989 | 5.41167 | 5.85522 | 5.35327 | 5.82599 | 6.15055 | 4.46715 | 5.33642 | 5.40791 | 5.13024 | 5.14604 | 6.39323 | 5.39785 | 5.65426 | 5.35112 | NA | NA | NA | NA | NA | NA | NA | NA |
| A7 | Fluorodopan | 73754 | 3.52105 | 3.47298 | 3.32135 | 3.38408 | 3.37147 | 3.46418 | 3.43197 | 3.49273 | 3.86595 | 3.25237 | 3.31775 | 3.26001 | 3.71006 | 3.28443 | 3.88863 | 3.21913 | 3.36151 | 3.40326 | 3.48834 | 3.36436 | 3.46226 | 3.36836 | 3.44127 | 3.38367 | 3.48988 | 3.37424 | 3.31629 | 3.32045 | 3.46658 | 3.39682 | 3.347 | 3.26235 | 4.09172 | 3.34938 | 4.23216 | 4.09936 | 3.2466 | 3.38608 | 3.30275 | 3.46699 | 3.56664 | 3.35369 | 3.66952 | 3.31987 | 3.29326 | 3.20089 | 3.38805 | 3.28227 | 4.17373 | 3.52867 | 3.5697 | 3.33898 | 3.43245 | 3.26263 | 3.29743 | 3.14825 | 3.3895 | 3.3967 | 3.50527 | 3.55249 |
| A7 | Hepsulfam | 329680 | 3.84696 | 3.34351 | 3.30313 | 3.50793 | 3.26381 | 3.5575 | 3.74949 | 4.30845 | 3.5395 | 3.86586 | 3.34251 | 3.22639 | 4.79919 | 3.96014 | 3.51587 | 3.56662 | 3.93722 | 3.71468 | 3.91334 | 4.0673 | 3.91659 | 3.33051 | 3.43159 | 3.52777 | 3.48069 | 3.42647 | 3.40305 | 3.43309 | 3.37030 | 3.54198 | 3.39425 | 3.35582 | 4.26207 | 3.46674 | 4.61460 | 4.50052 | 3.5407 | 3.87562 | 3.44441 | 4.21865 | 3.48465 | 3.83508 | 4.23078 | 3.19078 | 3.41067 | 3.48155 | 3.40640 | 3.24717 | 4.61878 | 3.51832 | 3.92808 | 3.54054 | 3.56946 | 3.88717 | 3.33718 | 3.23556 | 3.38702 | 3.37545 | 3.81972 | 3.67294 |
| A7 | Iproplatin | 256927 | 4.72537 | 4.72776 | 4.37873 | 4.68121 | 4.42767 | 4.56066 | 4.37508 | 4.54171 | 4.75155 | 4.43718 | 4.18446 | 4.50246 | 5.02113 | 4.29757 | 4.29334 | 4.23809 | 3.97704 | 4.58348 | 4.40027 | 4.30491 | 4.33135 | 4.82764 | 4.01030 | 4.72751 | 4.64535 | 4.43125 | 4.01979 | 4.64876 | 4.54051 | 4.4719 | 4.52317 | 4.5769 | 5.27161 | 4.4963 | 4.93255 | 4.91457 | 3.79810 | 4.49571 | 3.77966 | 4.52934 | 4.55755 | 4.45173 | 4.87190 | 3.74675 | 4.03106 | 4.20013 | 4.57264 | 4.1877 | 4.79756 | 4.48199 | 4.67851 | 4.23423 | 3.98151 | 4.41424 | 4.19877 | 3.97337 | 4.58436 | 4.68119 | 4.41299 | 4.29928 |
| A7 | Mechlorethamine | 762 | 5.62412 | 5.89173 | 5.0067 | 5.32375 | 5.04459 | 5.91527 | 5.29577 | 5.64094 | 6.17557 | 5.67439 | 5.15095 | 5.01438 | 6.87645 | 5.23678 | 6.1151 | 4.79265 | 4.87486 | 5.56341 | 5.50468 | 5.47829 | 5.81819 | 5.27636 | 5.23671 | 5.37607 | 5.63231 | 5.56973 | 5.17609 | 5.17042 | 5.05414 | 4.93999 | 5.17264 | 5.08629 | 6.67897 | 5.11507 | 6.56103 | 6.80604 | 5.10014 | 6.11371 | 5.15408 | 6.30023 | 5.67210 | 5.78095 | 6.65571 | 5.09158 | 5.20565 | 5.03051 | 5.27258 | 5.15856 | 6.70756 | 5.79073 | 5.71265 | 5.11051 | 5.36537 | 6.11354 | 4.84769 | 4.29659 | 5.12913 | 5.14636 | 5.22906 | 6.50511 |
| A7 | Melphalan | 8806 | 4.74759 | 4.51915 | 4.27896 | 4.43541 | 4.27918 | 4.62330 | 4.67815 | 4.94934 | 4.48936 | 4.56699 | 4.26497 | 4.14588 | 5.08277 | 4.79237 | 4.42134 | 4.30761 | 4.43498 | 4.57577 | 4.72923 | 4.75242 | 4.81525 | 4.17641 | 4.33475 | 4.41505 | 4.4416 | 4.42204 | 4.17602 | 4.32065 | 4.37989 | 4.45474 | 4.29433 | 4.48575 | 5.65107 | 4.31619 | 5.66124 | 5.77899 | 4.35231 | 4.85864 | 3.91625 | 4.84301 | 4.49079 | 4.83196 | 4.94814 | 4.22652 | 4.37632 | 4.3454 | 4.37204 | 4.3216 | 5.61294 | 4.37045 | 4.93023 | 4.31834 | 4.47224 | 4.37083 | 4.21991 | 4.25979 | 4.38963 | 4.35817 | 4.47116 | 4.87131 |
| A7 | Piperazine mustard | 344007 | 4.10381 | 3.90024 | 3.46800 | 3.66783 | 3.42757 | 4.13316 | 3.88973 | 4.91491 | 4.00001 | 3.90987 | 3.64853 | 3.04374 | 5.18451 | 4.20628 | 3.84887 | 3.73183 | 3.90310 | 3.99213 | 4.21318 | 4.34301 | 4.43267 | 3.56969 | 3.4941 | 3.68278 | 3.70666 | 3.68477 | 3.25571 | 3.73146 | 3.73952 | 3.87831 | 3.5539 | 3.69993 | 5.061 | 3.71736 | 5.11821 | 4.97775 | 3.7906 | 4.53066 | 3.68718 | 4.77112 | 3.83435 | 4.35465 | 5.02106 | 3.39173 | 3.6753 | 3.75839 | 3.82311 | 3.65418 | 5.21132 | 3.83060 | 4.27091 | 3.85009 | 3.61905 | 4.21767 | 3.37323 | 3.54241 | 3.51497 | 3.74260 | 3.80895 | 4.17218 |
| A7 | Piperazinedione | 135758 | 6.66624 | 5.9233 | 5.50518 | 5.90325 | 5.5103 | 6.6553 | 6.81625 | 7 | 5.95141 | 6.58163 | 5.43171 | 5.20964 | 7 | 6.69686 | 5.83454 | 5.85122 | 6.06103 | 6.45612 | 6.45977 | 6.81094 | 6.34375 | 5.60443 | 5.76300 | 6.026 | 5.76603 | 5.74202 | 5.39474 | 5.58596 | 5.57969 | 5.97107 | 5.35164 | 5.82511 | 7 | 5.65076 | 7 | 7 | 5.73717 | 6.74477 | 5.64113 | 6.51439 | 5.87597 | 7 | 7 | 5.35472 | 5.52327 | 5.75869 | 5.69416 | 5.70338 | 7 | 5.58245 | 7 | 5.88027 | 5.8834 | 7 | 5.65339 | 5.29601 | 5.97288 | 6.1368 | 5.78908 | 6.65317 |
| A7 | Pipobroman | 25154 | 4.25505 | 4.0094 | 3.9777 | 4.12989 | 4.00803 | 4.20731 | 4.19308 | 4.72880 | 4.14674 | 4.25852 | 3.96037 | 3.96456 | 4.96627 | 4.18633 | 3.95623 | 4.05345 | 4.11617 | 4.23056 | 4.31631 | 4.21333 | 4.17905 | 4.04019 | 4.06919 | 4.14746 | 4.05927 | 4.08224 | 4.06738 | 3.98742 | 4.08305 | 4.04687 | 4.00664 | 3.97933 | 4.69564 | 3.84962 | 4.82558 | 5.17532 | 3.92125 | 4.31272 | 4.07561 | 4.18972 | 4.12991 | 4.16784 | 4.52498 | 3.62829 | 4.03724 | 4.10758 | 4.04283 | 4.01337 | 4.81614 | 3.93414 | 4.25778 | 4.11144 | 3.99258 | 4.16661 | 3.92761 | 3.75667 | 4.02962 | 4.06489 | 4.11696 | 3.80927 |
| A7 | Spiromustine | 172112 | 4.0254 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 4.07204 | NA | 4.18796 | 4.24087 | 3.76483 | 3.60206 | 3.60206 | 4.11844 | 3.79921 | 4.19041 | 3.65687 | 3.60356 | 3.65626 | 4.06377 | 3.96783 | 4.09594 | 3.60206 | 3.60206 | 3.64719 | 3.68050 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 4.3745 | 3.60206 | 4.48295 | NA | 3.60206 | 3.96455 | 3.60206 | 4.38530 | 4.14102 | NA | NA | NA | 3.60206 | 3.60206 | 3.60206 | 3.60206 | 4.50751 | 3.86548 | 3.99809 | 3.60206 | NA | NA | NA | NA | NA | NA | NA | NA |
| A7 | Teroxirone | 296934 | 4.85672 | 4.48022 | 4.40309 | 4.57458 | 4.47146 | 5.09412 | 4.93876 | 5.86844 | 5.23765 | 5.20218 | 4.38643 | 4.52135 | 5.93845 | 4.80400 | 4.50809 | 4.6772 | 4.90786 | 5.29436 | 4.84648 | 5.33578 | 5.28868 | 4.76828 | 4.72267 | 4.91166 | 4.54945 | 4.86223 | 4.50582 | 4.85843 | 4.46621 | 4.59857 | 4.53667 | 4.6774 | 5.66241 | 4.59857 | 6.02224 | 5.90245 | 4.52013 | 5.37836 | 4.8516 | 5.29262 | 4.72794 | 5.12498 | 5.98724 | 4.39056 | 4.73426 | 4.5588 | 4.78155 | 4.36638 | 6.10578 | 4.84614 | 5.29699 | 4.76964 | 4.61967 | 5.05328 | 4.34599 | 4.42591 | 4.74776 | 4.5216 | 4.70398 | 4.72071 |
| A7 | Tetraplatin | 363812 | 6.03337 | 6.70863 | 5.23656 | 6.46833 | 5.88892 | 5.90933 | 5.73874 | 6.25065 | 6.39314 | 6.15128 | 4.8758 | 5.18322 | 6.40877 | 5.31156 | 5.21563 | 5.39750 | 5.24269 | 5.79523 | 5.85206 | 6.00152 | 5.85206 | 6.51737 | 6.05525 | 6.66175 | 6.74368 | 6.15942 | 5.73962 | 5.6813 | 5.54364 | 5.87978 | 6.10202 | 5.00358 | 6.56652 | 6.27094 | 6.90356 | 6.24542 | 5.63711 | 6.04875 | 5.37725 | 6.15802 | 5.61882 | 6.73523 | 6.00389 | 5.19349 | 5.54272 | 5.98384 | 6.26871 | 5.70083 | 6.49272 | 7.0142 | 6.21678 | 5.82379 | 5.9858 | 5.48543 | 4.47149 | 5.45168 | 5.98515 | 6.08781 | 5.59054 | 5.94928 |
| A7 | Thiotepa | 6396 | 4.39992 | 3.80185 | 3.6796 | 3.91724 | 3.72079 | 4.4378 | 4.13672 | 4.87388 | 3.96464 | 4.2874 | 3.55091 | 3.62366 | 5.28829 | 4.48089 | 3.81433 | 3.88064 | 3.98424 | 4.22418 | 4.42117 | 4.49834 | 4.45406 | 3.81692 | 3.87306 | 3.91479 | 3.82369 | 3.83542 | 3.7829 | 3.75652 | 3.72338 | 3.93827 | 3.77809 | 3.9016 | 5.03805 | 3.79282 | 5.16864 | 5.15960 | 3.96211 | 4.45146 | 3.86472 | 4.51067 | 3.92260 | 4.41489 | 4.82209 | 3.4815 | 3.84564 | 3.88527 | 3.80563 | 3.84482 | 5.18193 | 3.70564 | 4.46668 | 3.9995 | 3.75954 | 4.38398 | 3.58051 | 3.42727 | 3.81474 | 3.84253 | 3.80378 | 3.74131 |
| A7 | Triethylenemelamine | 9706 | 5.49618 | 4.90454 | 4.74009 | 5.17079 | 4.82588 | 5.54915 | 5.31844 | 5.72766 | 5.29688 | 5.29211 | 4.62273 | 4.71684 | 6.38258 | 5.66573 | 4.91107 | 5.09747 | 5.25337 | 5.40834 | 5.54785 | 5.55591 | 5.56919 | 4.84195 | 4.92375 | 4.99784 | 4.92339 | 4.88297 | 4.80808 | 4.75631 | 4.77103 | 5.05841 | 4.81198 | 5.03707 | 6.12676 | 4.97161 | 6.32915 | 6.33977 | 5.10147 | 5.57649 | 4.92612 | 5.63356 | 5.02676 | 5.51222 | 6.07076 | 4.54978 | 4.88865 | 4.97628 | 4.83902 | 4.93178 | 6.21912 | 4.83744 | 5.62404 | 5.22304 | 4.84497 | 5.43273 | 4.6642 | 4.60427 | 4.86355 | 4.85762 | 4.7837 | 5.09055 |
| A7 | Uracil mustard | 34462 | 4.86274 | 4.37033 | 4.03085 | 4.26535 | 4.13087 | 4.8651 | 4.69077 | 5.14307 | 4.90127 | 4.61669 | 4.02987 | 3.95266 | 5.4713 | 4.84193 | 4.59917 | 4.32490 | 4.56507 | 4.82041 | 4.86930 | 4.80155 | 4.92344 | 4.14579 | 4.13753 | 4.28475 | 4.26032 | 4.26727 | 4.0552 | 4.0572 | 4.08996 | 4.2966 | 4.0924 | 4.24961 | 5.63377 | 4.33401 | 5.77502 | 5.84347 | 4.34945 | 5.01888 | 4.11117 | 5.44485 | 4.71741 | 4.98714 | 5.50669 | 3.97048 | 4.23959 | 4.24357 | 4.16649 | 4.33344 | 5.77272 | 4.35928 | 4.75422 | 4.56649 | 4.26397 | 4.66213 | 4.04838 | 4.04807 | 4.19475 | 4.22775 | 4.2162 | 5.077 |
| A7 | Yoshi-864 | 102627 | 3.0623 | 2.76817 | 2.64116 | 2.8205 | 2.61596 | 2.89733 | 2.83765 | 3.40789 | 2.71503 | 3.12944 | 2.64843 | 2.67373 | 3.72987 | 3.16803 | 2.81749 | 2.78954 | 2.77203 | 3.00465 | 3.0804 | 3.32868 | 2.81510 | 2.73863 | 2.76935 | 2.8647 | 2.82072 | 2.72767 | 2.72305 | 2.69029 | 2.63751 | 2.71121 | 2.60495 | 2.65028 | 3.48093 | 2.71813 | 3.65626 | 3.74798 | 2.60779 | 3.22242 | 2.76758 | 3.21367 | 2.7154 | 3.04413 | 3.34247 | 2.63697 | 2.71683 | 2.65857 | 2.76391 | 2.65776 | 3.61244 | 2.82238 | 3.18345 | 2.75255 | 2.91427 | 3.15758 | 2.53782 | 2.58694 | 2.64408 | 2.60404 | 2.82446 | 2.94026 |
| T1 | Camptothecin | 94600 | 7.63805 | 6.76889 | 6.46891 | 7.52587 | 6.68512 | 7.66723 | 7.68451 | 8 | 7.74759 | 7.89902 | 6.93995 | 6.76962 | 8 | 8 | 7.21967 | 7.83587 | 7.46352 | 8 | 8 | 8 | 8 | 7.25699 | 6.68834 | 7.71354 | 7.49242 | 6.85542 | 6.88388 | 6.74523 | 6.63709 | 7.59498 | 6.68315 | 7.67597 | 8 | 7.22152 | 8 | 8 | 7.57459 | 7.94061 | 7.6173 | 8 | 7.62289 | 7.67047 | 7.93415 | 5.87847 | 7.19669 | 7.88541 | 6.57351 | 6.98894 | 8 | 7.56446 | 8 | 8 | 7.19132 | 8 | 6.02817 | 6.08842 | 7.18153 | 6.83799 | 6.93993 | 7.64661 |
| T1 | "Camptothecin,7-Cl" | 249910 | 8 | 6.51306 | 6.09356 | 8 | 6.47178 | 8 | 8 | 8 | 8 | 8 | 6.22565 | 6.68920 | 8 | 8 | 7.22206 | 8 | 7.91538 | 8 | 8 | 8 | 8 | 7.22578 | 6.28319 | 7.79635 | 7.56035 | 6.71926 | 6.6752 | 6.52188 | 6.25154 | 7.97166 | 6.49863 | 7.78959 | 8 | 7.56757 | 8 | 8 | 8 | 8 | 7.76747 | 8 | 8 | 8 | 8 | 4.96522 | 6.63235 | 8 | 6.30273 | 7.26071 | 8 | 8 | 8 | 8 | 7.66964 | 8 | 5.07994 | 5.34493 | 7.00722 | 7.16126 | 7.86697 | 8 |
| T1 | "Camptothecin,9-MeO" | 176323 | 8 | 6.91537 | 6.66713 | 7.86767 | 6.2461 | 8 | 7.39988 | 8 | 7.68033 | 7.87128 | 6.50537 | 6.70702 | 8 | 8 | 7.33473 | 8 | 7.90546 | 8 | 8 | 8 | 8 | 7.02164 | 5.41507 | 7.74369 | 7.41304 | 6.71072 | 6.73609 | 6.56594 | 6.61384 | 7.75845 | 6.66214 | 7.86172 | 8 | 7.14986 | 7.70852 | 8 | 7.98762 | 8 | 6.95571 | 8 | 7.59655 | 7.35105 | 8 | 5.82661 | 6.73912 | 7.72184 | 6.44190 | 7.08114 | 8 | 7.94542 | 6 | 5.77714 | 5.81497 | 6 | 5.22074 | 4.89413 | 6.63230 | 6 | 5.30613 | 4 |
| T1 | "Camptothecin,9-NH2 (RS)" | 629971 | 8 | 6.76238 | 6.46151 | 7.6 | 6.73353 | 8 | 8 | 8 | 8 | 7.28872 | 6.06002 | 6.88068 | 8 | 8 | 7.48317 | 8 | 7.96899 | 8 | 8 | 8 | 8 | 6.93166 | 6.50871 | 7.88036 | 7.75957 | 6.61633 | 6.52632 | 6.49236 | 6.45488 | 7.56458 | 6.42667 | 7.56538 | 8 | 7.54808 | 8 | 8 | 8 | 8 | 6.90988 | 8 | 7.53267 | 8 | 8 | 5.43343 | 6.93296 | 8 | 6.09517 | 6.97582 | 8 | 7.33109 | 8 | 7.92865 | 6.93763 | 7.95874 | 5.67744 | 5.43773 | 7.21726 | 6.74093 | 7.17536 | 7.85988 |
| T1 | "Camptothecin,9-NH2 (S)" | 603071 | 8 | 6.96265 | 6.66624 | 7.92172 | 6.7811 | 8 | 8 | 8 | 7.86124 | 7.67713 | 6.02211 | 6.91538 | 8 | 8 | 7.43433 | 8 | 8 | 8 | 8 | 8 | 8 | 7.14185 | 6.85223 | 7.81553 | 7.64732 | 6.77182 | 6.57891 | 6.80366 | 6.56221 | 7.89893 | 6.65679 | 7.91933 | 8 | 7.36796 | 8 | 8 | 7.96662 | 8 | 7.21215 | 8 | 7.34106 | 8 | 8 | 5.94495 | 7.17567 | 8 | 6.5703 | 6.74409 | 8 | 6.80103 | 8 | 8 | 7.12226 | 8 | 6.5841 | 5.3951 | 6.96619 | 6.96649 | 6.86219 | 8 |
| T1 | "Camptothecin,10-OH" | 107124 | 8.08003 | 7.24450 | 6.35385 | 7.61545 | 6.78419 | 7.92799 | NA | 8.12494 | 8.12494 | 7.21423 | 7.05299 | 6.97418 | 7.78629 | 8.12494 | 7.31171 | 8.12494 | 7.85439 | 8.12494 | 8.12494 | 7.65481 | 8.12494 | 6.80213 | 7.13059 | 7.80660 | 7.58857 | 6.6025 | 6.93271 | 7.25071 | 6.83604 | 7.96479 | 6.3009 | 7.64213 | 8.12494 | 7.22837 | 8.12494 | NA | 7.78431 | 8.04912 | 6.94298 | 8.12494 | 7.33329 | NA | NA | NA | 7.38615 | 8.0964 | 6.49621 | 7.54774 | 7.64571 | 6.59319 | 8.12494 | 7.71949 | NA | NA | NA | NA | NA | NA | NA | NA |
| T1 | "Camptothecin,11-formyl (RS)" | 606172 | 6.30135 | 5.44353 | 4.84646 | 5.69798 | 4.63039 | 5.71895 | 5.94571 | 6.39569 | 5.57015 | 5.54933 | 4.77585 | 5.09745 | 6.30268 | 6.63278 | 5.04356 | 5.51533 | 5.97095 | 6.26776 | 6.4085 | 5.49068 | 6.30275 | 5.3058 | 5.33521 | 5.8822 | 5.98799 | 5.21630 | 4.0626 | 5.29139 | 5.46068 | 5.79389 | 5.12955 | 5.68548 | 7.30815 | 5.68115 | 6.91243 | 7.88657 | 5.65811 | 6.35906 | 5.38306 | 5.76249 | 5.65781 | 6.24493 | 6.18649 | 4.37998 | 5.23595 | 5.80054 | 4.95075 | 5.33625 | 5.899 | 5.5655 | 6.72754 | 5.87629 | 5.29931 | 6.30961 | 4.71276 | 4.56866 | 5.2293 | 5.4084 | 5.34111 | 6.38462 |
| T1 | "Camptothecin,11-HOMe (RS)" | 606173 | 5.73787 | 5.34376 | 4.74361 | 5.51061 | 4.1049 | 5.68275 | 5.44451 | 6.1211 | 5.78629 | 5.21867 | 4.77513 | 5.14354 | 5.96426 | 6.24736 | 4.78764 | 5.71537 | 5.66108 | 6.15162 | 6.00161 | 5.49732 | 5.84889 | 5.02914 | 5.08347 | 5.31370 | 5.12401 | 4.80669 | 5.02928 | 5.34224 | 4.6236 | 5.58218 | 4.91237 | 5.64522 | 6.7312 | 5.36705 | 6.49218 | 7.18993 | 5.41866 | 5.81389 | 5.10691 | 5.52676 | 5.13905 | 5.70199 | 5.54446 | 4.02137 | 4.9138 | 5.79900 | 4.84682 | 5.04705 | 5.58987 | 5.14957 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| T1 | "Camptothecin,20-ester (S)" | 606497 | 7.05706 | 5.81491 | 5.57527 | 6.56913 | 5.457 | 7.24984 | 6.72736 | 7.48361 | 6.67526 | 6.76497 | 5.41617 | 5.93555 | 7.50401 | 7.34171 | 5.87812 | 6.92618 | 6.52452 | 7.2369 | 7.12126 | 7.22783 | 7.29771 | 6.08082 | 5.89576 | 6.51118 | 6.4308 | 5.73741 | 5.84033 | 5.66123 | 5.57000 | 6.58005 | 5.72675 | 6.64922 | 7.92256 | 6.22403 | 7.63741 | 8 | 6.66587 | 7.19390 | 6.2293 | 7.30118 | 6.57750 | 7.30905 | 7.37070 | 5.07408 | 6.18987 | 6.76581 | 5.80618 | 6.31238 | 7.20739 | 6.62490 | 7.15923 | 6.94336 | 6.12987 | 7.33269 | 5.17297 | 4.58769 | 5.86453 | 5.86829 | 5.97931 | 6.69283 |
| T1 | "Camptothecin,20-ester (S)" | 606985 | 8.05049 | 6.70830 | 6.30761 | 7.72766 | 6.07013 | 7.71917 | 7.74758 | 8.10411 | 7.44099 | 7.32606 | 6.7851 | 6.66242 | 8.48302 | 7.02419 | 7.01292 | 7.89422 | 7.73825 | 7.92964 | 8.16177 | 8.60464 | 7.42247 | 6.95605 | 6.7581 | 7.28471 | 7.34834 | 6.71743 | 7.65799 | 6.51113 | 6.59155 | 7.39794 | 6.87433 | 7.65033 | 8.93458 | 6.77038 | 8.85811 | 9.90406 | 7.78695 | 8.14568 | 7.89072 | 8.13109 | 6.82938 | 8.24982 | 8.32268 | 6.14218 | 7.06585 | 7.81985 | 6.55901 | 7.13794 | 8.11727 | 7.5084 | 7.60085 | 7.76082 | 6.76499 | 8.27122 | 6.18569 | 6 | 6.88497 | 6.91207 | 6.3379 | 7.37028 |
| T1 | "Camptothecin,20-ester (S)" | 610456 | 7.44302 | 6.40915 | 5.75895 | 6.90559 | 5.99675 | 7.27196 | 7.28991 | 7.79431 | 6.92586 | 7.10563 | 5.91234 | 6.33856 | 8 | 7.94865 | 5.93695 | 7.28434 | 6.94438 | 7.58824 | 7.41804 | 7.58703 | 7.52084 | 6.53830 | 6.33855 | 6.98263 | 6.85392 | 6.31309 | 6.20122 | 6.04551 | 5.84135 | 6.83254 | 6.31788 | 6.81022 | 8 | 6.45466 | 8 | 8 | 7.15340 | 7.46682 | 6.69699 | 7.55618 | 6.57078 | 7.5315 | 7.63990 | 5.45576 | 6.6314 | 7.01069 | 6.00808 | 6.47802 | 7.50393 | 6.69477 | 7.54174 | 7.41721 | 6.62155 | 7.56746 | 5.41293 | 4.83582 | 6.36242 | 5.96431 | 6.31487 | 7.18684 |
| T1 | "Camptothecin,20-ester (S)" | 618939 | 7.70292 | 6.3 | 6.03693 | 7.48416 | 6.49311 | 7.46823 | 7.26162 | 8.14668 | 6.384 | 7.37378 | 6.04881 | 6.59415 | 8.06569 | 7.63110 | 7.00106 | 7.7491 | 7.12534 | 7.91869 | 7.78302 | 7.66424 | 7.70016 | 6.91753 | 6.83902 | 7.5302 | 7.04966 | 6.66234 | 6.6958 | 6.45206 | 6.30588 | 7.33356 | 6.61580 | 7.11708 | 8.69824 | 7.11467 | 8.4563 | 8.67223 | 7.5555 | 7.48007 | 6.68921 | 7.67551 | 6.85706 | 7.58741 | 8.05857 | 5.65909 | 6.86255 | 7.34673 | 6.40423 | 6.60651 | 7.98033 | 8.33354 | 8.06861 | 7.37555 | 7.01189 | 7.88466 | 5.48489 | 5.37269 | 6.71150 | 6.76312 | 7.27092 | 7.69232 |
| T2 | Amonafide | 308847 | 5.53792 | 5.49563 | 5.35161 | 5.46522 | 5.16955 | 5.41102 | 5.42921 | 5.46724 | 5.40421 | 5.77406 | 5.19227 | 5.31782 | 6.01365 | 5.56442 | 5.44946 | 5.35181 | 5.25778 | 5.38993 | 5.21202 | 5.46699 | 5.34536 | 5.44817 | 5.44166 | 5.73826 | 5.76056 | 5.49188 | 5.31508 | 5.29804 | 5.31693 | 5.56979 | 5.39297 | 5.30132 | 5.53108 | 5.5346 | 6.09872 | 5.84838 | 5.35682 | 5.45821 | 5.44609 | 5.82335 | 5.39077 | 5.62578 | 6.11081 | 5.38390 | 5.32807 | 5.56503 | 5.6807 | 5.24817 | 5.57622 | 5.34805 | 5.81394 | 5.47144 | 5.66769 | 5.51284 | 5.28177 | 5.30798 | 5.47237 | 5.6183 | 5.369 | 5.25247 |
| T2 | Amsacrine | 249992 | 6.70327 | 6.17951 | 5.41529 | 6.44821 | 5.52492 | 6.85608 | 6.6207 | 6.62916 | 6.21282 | 7.60206 | 5.55666 | 5.40503 | 7.60206 | 7.16393 | 6.2031 | 6.48301 | 6.33704 | 6.79451 | 6.30833 | 6.96374 | 6.69288 | 5.69458 | 5.86917 | 6.07437 | 6.23195 | 6.13276 | 5.82163 | 5.51799 | 5.39687 | 6.23219 | 5.53070 | 6.34551 | 7.37940 | 6.06302 | 7.60206 | 7.60206 | 6.08606 | 6.86616 | 6.47751 | 7.11219 | 5.66316 | 6.83791 | 7.41187 | 5.52625 | 5.49759 | 6.95295 | 5.52414 | 5.73246 | 7.55821 | 6.4209 | 7.02672 | 5.32500 | 6.49842 | 7.42716 | 5.45626 | 5.56657 | 5.36164 | 5.41719 | 5.94616 | 6.10130 |
| T2 | Anthrapyrazole-derivative | 355644 | 7.00512 | 6.39169 | 5.77794 | 6.84017 | 5.77712 | 6.97037 | 6.20343 | 6.94076 | 6.97265 | 7.61349 | 5.72135 | 6.41414 | 8 | 7.67888 | 6.70774 | 7.49058 | 7.51337 | 7.84972 | 7.02696 | 7.35973 | 7.38832 | 6.27741 | 6.61012 | 6.74375 | 6.61046 | 5.65573 | 6.40696 | 5.89232 | 5.96155 | 6.67747 | 6.15499 | 6.84731 | 7.50164 | 6.4845 | 7.58526 | 7.42693 | 5.82841 | 7.44165 | 6.8157 | 7.13873 | 6.23864 | 7.09394 | 7.03535 | 5.82263 | 5.79127 | 7.66944 | 6.2529 | 5.99834 | 7.21059 | 6.95503 | 7.40892 | 4.77179 | 6.25489 | 7.19385 | 6.01368 | 6.47967 | 6.03459 | 5.93287 | 6.54426 | 6.20892 |
| T2 | Bisantrene | 337766 | 7.24278 | 6.78144 | 6.74721 | 6.57282 | 6.53067 | 6.88766 | 6.55998 | 6.94704 | 7.15786 | 7.54679 | 6.71701 | 6.91476 | 7.60206 | 7.07093 | 7.12885 | 7.09832 | 7.22888 | 7.15279 | 7.08203 | 6.34602 | 6.95166 | 7.04242 | 6.74182 | 7.15661 | 6.94830 | 4.78402 | 6.95105 | 6.78278 | 6.7455 | 6.47726 | 6.61256 | 6.76769 | 7.60206 | 7.07488 | 7.60206 | 6.93593 | 4.67023 | 7.09759 | 6.42391 | 6.10909 | 6.47606 | 7.03291 | 6.51816 | 6.04727 | 6.57706 | 7.13633 | 7.21816 | 6.45171 | 7.23251 | 7.04318 | 7.35452 | 3.94222 | 7.03885 | 7.13108 | 5.18294 | 7.11963 | 6.80945 | 6.90415 | 6.68359 | 6.61112 |
| T2 | Daunorubicin | 82151 | 7.6018 | 7.26218 | 6.58208 | 7.18791 | 6.57608 | 7.18766 | 6.77042 | 7.14954 | 7.25454 | 7.24074 | 6.1612 | 6.44532 | 8.30103 | 7.62760 | 7.13677 | 7.40551 | 7.05513 | 7.57692 | 7.10699 | 7.18522 | 7.26399 | 7.09281 | 6.73285 | 7.6139 | 7.66457 | 6.10337 | 6.85337 | 6.74790 | 6.42215 | 7.24177 | 7.02184 | 6.82967 | 8.03383 | 7.36271 | 8.30103 | 8.30103 | 6.28541 | 7.44565 | 6.78539 | 7.01730 | 6.86563 | 7.57341 | 7.49295 | 6.39489 | 6.68602 | 7.44034 | 6.79955 | 6.66503 | 8.06848 | 7.57497 | 8.30103 | 5.20733 | 7.09495 | 7.00638 | 6.65692 | 6.81452 | 6.66057 | 6.77795 | 6.72565 | 7.18364 |
| T2 | Deoxydoxorubicin | 267469 | 7.89985 | 7.33091 | 6.82201 | 7.39037 | 6.87176 | 7.42215 | 7.12442 | 7.47155 | 7.22459 | 7.98156 | 6.80166 | 6.83721 | 9 | 7.63139 | 7.48214 | 7.45451 | 7.2712 | 7.65327 | 7.30061 | 7.47685 | 7.46386 | 7.38131 | 6.99341 | 7.74648 | 7.67678 | 6.81018 | 7.05515 | 6.91739 | 7.16088 | 7.3565 | 7.33526 | 7.21312 | 7.83652 | 7.57388 | 8.64769 | 8.64382 | 6.72469 | 7.53571 | 6.86668 | 8.03908 | 6.91438 | 7.56089 | 7.80854 | 6.74148 | 6.93724 | 7.44935 | 6.96184 | 6.93196 | 7.93435 | 7.71594 | 8.27071 | 5.56212 | 7.14851 | 7.61634 | 6.63399 | 6.76007 | 6.88146 | 6.96411 | 6.97389 | 7.22919 |
| T2 | Doxorubicin | 123127 | 7.30854 | 7.14829 | 6.51598 | 7.13064 | 6.47513 | 6.94782 | 6.63148 | 7.14952 | 7.19364 | 7.03920 | 6.19914 | 6.28299 | 8.60206 | 7.22866 | 7.02657 | 7.21116 | 7.03994 | 7.27969 | 6.9707 | 6.99374 | 7.12423 | 6.67657 | 6.56379 | 7.11139 | 7.0465 | 5.84093 | 6.50431 | 6.29347 | 6.13308 | 6.81925 | 6.89075 | 6.58705 | 7.39052 | 7.02879 | 8.00555 | 7.78565 | 6.12831 | 7.02061 | 6.7949 | 6.75929 | 6.54942 | 7.22922 | 7.12049 | 6.2593 | 6.55784 | 7.30286 | 6.57343 | 6.14514 | 7.25036 | 7.26934 | 7.72946 | 4.73697 | 6.57545 | 6.90791 | 6.33764 | 6.52331 | 6.50742 | 6.52207 | 6.45805 | 6.96347 |
| T2 | Etoposide | 141540 | 5.69324 | 4.99704 | 4.83747 | 5.3915 | 4.74434 | 5.42654 | 5.99769 | 5.61028 | 5.42365 | 5.66868 | 4.72 | 4.13385 | 6.49660 | 5.88986 | 5.37714 | 5.47343 | 5.13324 | 5.7157 | 5.31629 | 5.50417 | 5.76125 | 4.76774 | 4.91635 | 4.95557 | 5.24646 | 4.78153 | 4.81435 | 4.48469 | 3.80608 | 5.18567 | 4.58669 | 5.06078 | 6.27954 | 5.11107 | 6.6539 | 6.51567 | 4.47409 | 5.49062 | 5.0291 | 5.66355 | 4.81436 | 5.94798 | 6.23688 | 5.56573 | 4.50391 | 5.61243 | 4.59834 | 4.75481 | 6.51662 | 5.73197 | 5.94109 | 4.21581 | 6.20367 | 6.05452 | 5.75726 | 6.08860 | 4.5491 | 5.94281 | 5.60674 | 6.07660 |
| T2 | Menogaril | 269148 | 6.0027 | 5.96324 | 5.63517 | 5.95207 | 5.26135 | 6.09718 | 6.00549 | 5.98946 | 5.95572 | 7.01715 | 5.1423 | 5.60673 | 7.73575 | 6.76399 | 5.98964 | 6.4099 | 6.20814 | 6.42039 | 5.99235 | 6.53014 | 5.95054 | 5.68428 | 5.64656 | 6.22147 | 6.18950 | 5.76764 | 5.73741 | 5.63180 | 5.29211 | 5.97898 | 5.67722 | 6.30021 | 6.77571 | 5.98182 | 7.92446 | 7.28982 | 5.75184 | 6.2702 | 5.90998 | 6.95871 | 5.78374 | 6.56701 | 6.96557 | 5.12728 | 4.97766 | 6.17924 | 5.66535 | 5.56774 | 6.86791 | 6.29231 | 7.03168 | 4.94986 | 6.24956 | 6.43232 | 5.60913 | 5.25112 | 5.76073 | 5.67923 | 5.71374 | 6.0452 |
| T2 | Mitoxantrone | 301739 | 7.56475 | 6.91978 | 6.38716 | 7.30392 | 6.34853 | 6.98249 | 6.95764 | 7.48027 | 7.3327 | 7.96278 | 6.85691 | 6.56788 | 8.60206 | 7.7516 | 7.51577 | 7.60924 | 7.90948 | 7.98727 | 7.4243 | 7.66295 | 8.03055 | 6.70076 | 6.63497 | 7.29866 | 7.16512 | 6.509 | 6.37426 | 6.33780 | 6.31567 | 7.38203 | 6.63765 | 7.17806 | 8.14177 | 7.00007 | 8.60206 | 8.11662 | 6.57193 | 8.29657 | 7.25984 | 8.11674 | 7.14175 | 7.69552 | 7.97673 | 6.37817 | 5.68362 | 7.57021 | 6.63234 | 6.54779 | 7.77384 | 6.57926 | 8.60206 | 5.41161 | 6.95463 | 7.46607 | 6.64297 | 7.22234 | 6.32690 | 6.50333 | 7.14945 | 7.254 |
| T2 | Oxanthrazole (piroxantrone) | 349174 | 6.05404 | 5.84068 | 5.59283 | 6.00831 | 5.39656 | 5.8978 | 5.47152 | 6.05229 | 5.88897 | 6.38671 | 5.48570 | 5.46476 | 6.81304 | 6.46943 | 6.26278 | 6.34412 | 6.12376 | 6.23615 | 5.86503 | 6.09148 | 5.98014 | 5.49089 | 5.43538 | 5.78505 | 5.95860 | 5.24613 | 5.53086 | 5.33322 | 5.41166 | 5.7831 | 5.56937 | 5.76198 | 6.28417 | 5.92331 | 6.59784 | 6.53557 | 5.15590 | 6.52635 | 5.63076 | 6.10528 | 5.55142 | 6.14093 | 6.16242 | 5.18309 | 5.2141 | 6.38202 | 5.73355 | 5.29314 | 6.2305 | 5.91928 | 6.32143 | 4.54831 | 5.40391 | 5.94533 | 5.38441 | 6.13513 | 5.51303 | 5.44589 | 6.15812 | 5.53141 |
| T2 | Teniposide | 122819 | 6.76244 | 6.18809 | 6.01051 | 6.40782 | 5.82873 | 6.33676 | 6.23591 | 6.53179 | 6.24462 | 6.80984 | 6.07452 | 5.33735 | 7.90119 | 6.85851 | 6.92574 | 6.72003 | 6.24627 | 6.78019 | 6.32487 | 6.78951 | 6.5279 | 5.84531 | 6.20376 | 6.04541 | 6.43828 | 5.76134 | 6.13460 | 5.81005 | 5.26794 | 6.21827 | 5.59930 | 6.17124 | 7.2667 | 6.15513 | 7.77599 | 8.58685 | 5.38403 | 6.48476 | 6.28733 | 7.05074 | 6.15571 | 6.59096 | 6.63749 | 5.83345 | 5.66774 | 6.09525 | 6.38913 | 5.75264 | 7.27573 | 6.83111 | 7.29338 | 4.60206 | 5.92112 | 6.45560 | 5.8649 | 6.38031 | 5.90472 | 5.98971 | 6.27722 | 6.79117 |
| T2 | Zorubicin (Rubidazone) | 164011 | 7.13103 | 6.85852 | 6.34938 | 6.5627 | 6.24076 | 6.66285 | 6.62723 | 6.60845 | 6.64895 | 6.66449 | 6.10595 | 6.00856 | 7.53109 | 6.73285 | 6.89991 | 6.79516 | 6.53110 | 6.76567 | 6.5638 | 6.75029 | 6.52836 | 6.19459 | 6.26409 | 7.06925 | 6.89671 | 5.65309 | 6.39596 | 6.26806 | 5.84822 | 6.53058 | 6.59919 | 6.30665 | 7.20051 | 6.58599 | 7.39564 | 7.90309 | 5.59281 | 6.85165 | 6.38144 | 6.80482 | 6.61140 | 7.2582 | 7.08282 | 6.28709 | 6.28564 | 6.85847 | 6.31496 | 6.15368 | 7.25364 | 6.76986 | 7.25756 | 4.70564 | 6.67800 | 6.88973 | 6.26221 | 6.45707 | 6.44057 | 6.47030 | 6.51685 | 6.7218 |
| Pi | L-Asparaginase | 109229 | -0.06403 | -1.23499 | -0.04615 | -0.82173 | 0.06238 | -0.45346 | -0.78553 | -0.52028 | -0.04036 | 0.02266 | 0.22549 | -0.13508 | -0.05195 | 0.18998 | -0.51567 | -0.64313 | -0.81817 | 0.02818 | -0.41212 | -0.03227 | -0.25229 | -0.47529 | -0.44004 | -0.50415 | -0.65746 | -0.57022 | -0.2058 | -0.99427 | -2.39794 | 0.11218 | -1.20162 | -0.22938 | 1.60206 | -0.76131 | 1.60206 | 0.47689 | -0.69544 | 0.41564 | 0.28864 | 0.01525 | 0.03518 | -0.16797 | -0.5782 | -0.67837 | -0.54362 | -0.06868 | -0.42062 | -0.05137 | 0.39936 | -0.27729 | -0.12563 | 0.50584 | -1.33751 | -0.60297 | -0.92963 | -0.86781 | -0.96131 | -0.87971 | -1.3059 | -1.07733 |
| Db | Cyanomorpholinodoxorubicin | 357704 | 10.84908 | 9.83001 | 10.1551 | 10.50587 | 9.82733 | 10.33113 | 10.10592 | 10.91147 | 10.35504 | 10.30187 | 9.46163 | 9.98104 | 11.00141 | 10.73411 | 10.03141 | 10.09409 | 10.63776 | 10.62813 | 10.21954 | 10.97752 | 10.45217 | 10.44246 | 10.08072 | 10.44093 | 10.02163 | 10.21509 | 10.26207 | 10.44516 | 10.37119 | 10.35773 | 10.0775 | 10.13344 | 10.44776 | 10.24625 | 10.56646 | 10.097 | 10.45416 | 10.46166 | 10.44393 | 10.43861 | 10.51841 | 10.59493 | 10.59654 | 9.43329 | 10.00389 | 10.57738 | 9.74499 | 10.12982 | 10.44465 | 10.43233 | 10.51639 | 10.0541 | 9.96027 | 10.23726 | 10.02469 | 10.22934 | 10.11606 | 10.07307 | 10.37642 | 10.04599 |
| Db | Hycanthone | 142982 | 5.26238 | 5.23662 | 4.82198 | 4.88368 | 4.83803 | 4.90695 | NA | 4.83492 | 5.06728 | 5.12124 | 4.79356 | 5.03142 | 5.49663 | 4.92612 | 4.99963 | 4.85796 | 4.88669 | 4.93798 | 4.99921 | 5.15378 | 5.08079 | 5.15503 | 5.02704 | 5.37369 | 5.26383 | 5.03627 | 4.94571 | 5.04955 | 5.18541 | 5.20532 | 4.86532 | 4.87649 | 5.34303 | 5.45475 | 5.50138 | NA | 5.20041 | 5.1327 | 5.21519 | 5.52113 | 5.30227 | NA | NA | NA | 5.05584 | 5.00024 | 5.378 | 4.96578 | 5.01063 | 5.00824 | 5.2543 | 5.14104 | NA | NA | NA | NA | NA | NA | NA | NA |
| Db | Morpholino-adriamycin | 354646 | 8.24484 | 7.77093 | 7.72914 | 7.80163 | 7.4387 | 7.59132 | 7.4189 | 8.01764 | 7.70333 | 8.12208 | 7.31382 | 7.92994 | 8.43911 | 7.56974 | 7.53879 | 7.59892 | 7.87992 | 7.79526 | 7.58401 | 7.80823 | 7.81615 | 7.96333 | 7.70014 | 8.51673 | 8.09443 | 7.7666 | 7.53297 | 7.62453 | 7.65615 | 8.12724 | 7.59795 | 7.36270 | 7.71078 | 8.04606 | 8.02399 | 8.30531 | 7.63912 | 7.69669 | 7.838 | 7.99702 | 7.65444 | 7.97843 | 8.32577 | 7.22451 | 7.6269 | 7.97991 | 7.82507 | 7.38298 | 7.62821 | 8.01922 | 7.53597 | 6.9612 | 7.47166 | 7.26171 | 7.33294 | 7.54171 | 7.31232 | 7.45462 | 7.44885 | 7.24325 |
| Db | N-N-Dibenzyl-daunomycin | 268242 | 5.38113 | 4.61951 | 4.30103 | 4.39983 | 4.30103 | 4.56959 | 4.32186 | 4.72551 | 4.69009 | 5.35465 | 4.30103 | 4.68248 | 6.0147 | 4.33494 | 4.30103 | 4.62847 | 4.30103 | 4.87033 | 4.8841 | 4.61000 | 4.41742 | 4.75286 | 4.30103 | 5.6963 | 5.32864 | 5.01003 | 4.71439 | 4.33242 | 4.54782 | 5.16044 | 4.92082 | 4.30103 | 5.18347 | 5.42854 | 5.90498 | 6.02506 | 4.75426 | 4.96223 | 4.30103 | 5.20853 | 4.30103 | 5.60406 | 5.66208 | 4.73931 | 4.32087 | 4.85979 | 4.62398 | 4.30103 | 4.72243 | 5.1943 | 4.84918 | 4.8828 | 4.94431 | 4.77195 | 4.72874 | 4.74604 | 5.38745 | 4.7624 | 4.56124 | 5.00782 |
| Db | Pyrazoloacridine | 366140 | 6.75499 | 6.09569 | 6.10161 | 6.3719 | 5.99227 | 6.37427 | 6.60971 | 6.27546 | 6.73938 | 6.60971 | 6.17871 | 6.52215 | 6.76886 | 6.63408 | 6.43362 | 6.47862 | 6.47436 | 6.69896 | 6.503 | 6.44360 | 6.61759 | 6.89125 | 6.53336 | 7.20412 | 6.97465 | 6.72166 | 6.53419 | 6.26628 | 6.44452 | 6.6902 | 6.51123 | 6.36887 | 6.80832 | 6.65567 | 6.72561 | 6.84932 | 6.59941 | 6.91245 | 6.15754 | 6.57082 | 6.63812 | 7.17106 | 7.20412 | 6.49480 | 5.81781 | 6.48214 | 6.88037 | 6.21964 | 6.44368 | 6.57561 | 6.5568 | 6.67980 | 7.08318 | 6.50141 | 6.57927 | 6.33357 | 6.81257 | 6.82814 | 6.01725 | 6.21635 |
| Di | 5-6-Dihydro-5-azacytidine | 264880 | 5.66928 | 4.96889 | 6.0239 | 4.30717 | 4.28634 | 4.00348 | 5.16074 | 4.75388 | 5.22352 | 4.79685 | 3.30913 | 5.02644 | 5.15567 | 3.84673 | 3.16378 | 3.81391 | 4.53367 | 4.58363 | 4.86293 | 4.37166 | 4.68442 | 4.33305 | 4.4495 | 4.82182 | 4.83114 | 5.26563 | 4.86855 | 4.39213 | 3.90438 | 3.31047 | 5.22223 | 4.03454 | 5.03536 | 5.68864 | 5.10195 | 5.34796 | 3.80171 | 3.22739 | 5.23345 | 3.95728 | 5.05743 | 5.17871 | 6.08363 | 4.93792 | 4.36199 | 5.24568 | 3.81245 | 3.89095 | 6.11027 | 5.78484 | 4.96043 | 3.13383 | 3.38299 | 3.77634 | 3.98616 | 4.61123 | 5.17813 | 5.1798 | 5.04362 | 4.93397 |
| Di | alpha-2'-Deoxythioguanosine | 71851 | 4.62203 | 3.64714 | 3.76623 | 3.50309 | 2.52703 | 3.72424 | 4.04288 | 4.25539 | 3.79296 | 3.60128 | 3.59563 | 3.41642 | 4.07296 | 3.86858 | 3.49773 | 2.78076 | 3.36282 | 3.50701 | 3.65685 | 3.94538 | 3.71921 | 3.77472 | 3.91136 | 3.93725 | 3.59710 | 3.84661 | 3.70449 | 3.94256 | 3.90514 | 3.92591 | 3.7027 | 4.25192 | 4.63924 | 4.18072 | 4.33 | 4.43824 | 3.85761 | 3.56477 | 3.668 | 3.94547 | 3.71515 | 3.92324 | 3.75264 | 4.02771 | 3.58649 | 3.39795 | 3.75874 | 3.85053 | 3.78296 | 4.55772 | 3.96448 | 4.28146 | 3.82801 | 4.09204 | 3.60261 | 3.32516 | 3.69371 | 3.72287 | 3.09968 | 3.94111 |
| Di | Azacytidine | 102816 | 6.41456 | 6.07142 | 6.60206 | 5.80718 | 5.89531 | 5.55158 | 6.33785 | 6.35093 | 6.10684 | 6.02586 | 5.53694 | 6.07498 | 6.60206 | 6.31421 | 5.54715 | 5.6732 | 5.67486 | 6.02682 | 5.88541 | 5.83877 | 6.05805 | 6.00347 | 6.16641 | 6.60206 | 6.12024 | 5.98267 | 6.07927 | 6.08507 | 6.26851 | 6.24478 | 6.16516 | 5.64937 | 6.28435 | 6.1969 | 6.01851 | 6.10766 | 6.12698 | 6.22586 | 6.02143 | 6.60141 | 6.21027 | 6.00134 | 6.36614 | 5.93294 | 5.76244 | 6.05206 | 6.17231 | 5.43025 | 6.60206 | 6.60206 | 6.06383 | 5.93718 | 6.18234 | 6.54894 | 6.37146 | 6.09298 | 6.24534 | 6.18254 | 6.14906 | 6.60206 |
| Di | beta-2'-Deoxythioguanosine | 71261 | 6.4486 | 5.91540 | 5.89644 | 5.49626 | 5.03742 | 5.94311 | 6.44944 | 6.42899 | 6.10945 | 5.42869 | 5.979 | 5.24761 | 6.2561 | 6.21888 | 5.63857 | 4.08095 | 5.41932 | 5.04798 | 6.12856 | 6.09513 | 6.17479 | 5.98005 | 5.83672 | 6.29258 | 5.79937 | 5.86085 | 5.7521 | 6.13194 | 6.16372 | 6.2782 | 5.3426 | 6.29672 | 6.55154 | 6.26302 | 6.43124 | 6.90309 | 6.12296 | 5.88874 | 5.40616 | 6.24642 | 6.19700 | 6.51394 | 6.0229 | 6.44094 | 5.35516 | 4.88543 | 5.68949 | 6.24508 | 5.6833 | 6.37419 | 6.26962 | 6.22943 | 6.15476 | 6.42230 | 6.20445 | 5.08475 | 6.31958 | 6.37929 | 5.39462 | 5.55614 |
| Di | Thioguanine | 752 | 6.71275 | 5.91548 | 6.01804 | 5.40900 | 4.98839 | 5.98033 | 6.20088 | 6.18824 | 6.10444 | 5.36219 | 5.77759 | 5.02292 | 6.14880 | 6.08288 | 6.12792 | 4.09654 | 5.90583 | 5.3366 | 5.95357 | 5.94831 | 5.97254 | 5.9297 | 6.03031 | 6.16204 | 5.84336 | 5.98433 | 5.7839 | 6.09744 | 5.90647 | 6.0991 | 5.22764 | 6.17814 | 6.86849 | 6.37991 | 6.63393 | 6.8695 | 5.91075 | 5.89938 | 5.09093 | 6.20771 | 6.08942 | 6.06665 | 5.76478 | 6.01334 | 5.7701 | 5.34066 | 5.78964 | 6.13355 | 5.99786 | 6.36694 | 6.13484 | 6.11171 | 5.7606 | 6.09612 | 5.75577 | 5.3236 | 6.04005 | 6.06217 | 5.56788 | 5.84546 |
| Df | Aminopterin | 132483 | 7.92665 | 4 | 4 | 6.34467 | 4.91942 | 6.50431 | 7.78835 | 7.29983 | 5.77764 | 5.87591 | 5.08897 | 6.26524 | 7.20681 | 6.12842 | 4.83983 | 6.65365 | 4 | 7.04764 | 6.43925 | 7.01098 | 5.22099 | 7.68178 | 6.2906 | 8 | 7.75843 | 7.36957 | 6.57485 | 5.12234 | 5.00364 | 7.13701 | 7.22724 | 4.33638 | 7.1735 | 8 | 7.12850 | 8 | 6.17708 | 6.24404 | 6.35862 | 7.50680 | 4 | 8 | 7.58153 | 5.29123 | 5.24609 | 4 | 5.33168 | 6.03285 | 4 | 4 | 6.99785 | 7.10222 | 8 | 7.23128 | 4 | 4 | 8 | 8 | 4.47797 | 4 |
| Df | Aminopterin-derivative | 134033 | 8 | 6.41623 | 4.58074 | 6.7401 | 6.25195 | 6.73604 | 7.12884 | 7.04935 | 6.31591 | 7.46148 | 5.19665 | 7.09411 | 7.48476 | 6.76668 | 4.05844 | 6.35921 | 4.6809 | 7.35682 | 7.27722 | 7.15371 | 6.58496 | 7.84631 | 6.66129 | 8 | 7.98509 | 7.7362 | 7.08352 | 6.14975 | 4 | 7.31348 | 7.24456 | 5.49349 | 7.3094 | 8 | 7.75838 | NA | 6.54305 | 6.52177 | 6.83884 | 7.05697 | 4.18119 | 8 | 7.59677 | 7.09451 | 6.58637 | 4.66532 | 6.06484 | 6.72489 | NA | 4.86861 | 7.23762 | 7.54937 | 8 | NA | 4 | 4 | 8 | 8 | 4.58779 | NA |
| Df | Aminopterin-derivative | 184692 | 8 | 6.06383 | 4 | 8 | 4.71563 | 8 | 8 | 8 | 6.24746 | 8 | 4 | 5.92405 | 8 | 6.57355 | 5.19136 | 5.69915 | 5.15123 | 7.26916 | 8 | 7.19565 | 8 | 8 | 7.38071 | 8 | 8 | 8 | 7.13303 | 4.31154 | 4 | 8 | 8 | 4 | 7.89425 | 8 | 8 | 8 | 6.38114 | 8 | 5.55282 | 8 | 4 | 8 | 8 | 4.815 | 5.30082 | 4 | 4.77665 | 5.22011 | 7.5014 | 6.60625 | 8 | 7.69863 | 8 | 7.90258 | 4 | NA | 8 | 8 | 4.59528 | 4.68818 |
| Df | an-antifol | 623017 | 8 | 4.27273 | 4 | 7.73553 | 8 | 8 | NA | 8 | 8 | 8 | 8 | NA | 8 | 7.69931 | 8 | 7.69462 | 5.84412 | 8 | 7.39793 | 8 | 8 | 8 | 8 | NA | 6 | 8 | 8 | 7.80336 | 5.11742 | 8 | 8 | 4.40306 | 7.15965 | 7.61599 | 7.7134 | NA | 6 | 7.10185 | 4 | 8 | 4 | NA | NA | NA | 6 | 4 | 6 | 6 | 8 | 8 | 8 | 6 | NA | NA | NA | NA | NA | NA | NA | NA |
| Df | an-antifol | 633713 | 9.42818 | 8.70685 | 7 | 8.23854 | 8.33382 | 8.39701 | 7.64663 | 8.89029 | 7.79661 | 8.42189 | 7.65588 | 7.64759 | 9.34686 | 8.34815 | 7.56188 | 7.6663 | 7 | 7.84328 | 8.73733 | 8.47828 | 8.46126 | 8.99248 | 8.87953 | 9.5523 | 9.0627 | 8.98023 | 8.52683 | 7.17032 | 7 | 8.82295 | 7.60361 | 7.29672 | 8.82937 | 9.41951 | 8.45191 | 9.37231 | 8.27416 | 8.64379 | 7.66624 | 8.65017 | 7.53395 | 9.26763 | 8.74189 | 7.50825 | 7.80892 | 7 | 7.11642 | 8.70682 | 9.30989 | 7 | 8.44011 | 8.56461 | 7 | 8.02032 | 7 | 7 | 8.50679 | 8.89791 | 7 | 7 |
| Df | Baker's-soluble-antifolate | 139105 | 7.33497 | 6.28173 | 4 | 8 | 5.51287 | 7.78269 | 7.0862 | 8 | 7.16591 | 8 | 4.03525 | 5.96199 | 8 | 5.65911 | 4 | 6.59973 | 6.03446 | 7.21896 | 7.45727 | 6.35302 | 7.57503 | 7.24076 | 5.375 | 7.42637 | 7.11403 | 4.43668 | 7.26421 | 4.9127 | 4.07078 | 6.02158 | 8 | 4 | 7.29323 | 8 | 7.36121 | 7.69248 | 4.00041 | 8 | 4.78390 | 4.50267 | 6.46748 | 7.38872 | 5.39983 | 4.41428 | 5.16988 | 4 | 6.25555 | 6.1617 | 7.39568 | 6.50146 | 7.56325 | 4 | 8 | 7.71198 | 4 | 4 | 7.61881 | 7.64842 | 4 | 4.87443 |
| Df | Methotrexate | 740 | 9 | 5 | 5 | 7.20081 | 5 | 7.21048 | 7.41257 | 8.21716 | 5 | 8.18042 | 5 | 6.19167 | 8.35856 | 7.92279 | 5 | 5 | 7.10671 | 7.30381 | 7.31553 | 8.05058 | 7.86997 | 7.69303 | 7.02485 | 8.73743 | 7.14711 | 8.30274 | 7.65577 | 6.16131 | 5 | 7.31300 | 7.02905 | 7.00732 | 7.82777 | 8.50103 | 7.47463 | 8.41136 | 7.21865 | 8.17561 | 5.67008 | 8.27930 | 5.48814 | 7.94671 | 7.78209 | 5 | 5 | 5 | 6.23945 | 7.72072 | 7.83323 | 7.22887 | 7.87123 | 7.40719 | 8.76296 | 7.64556 | 5 | 5 | 7.58501 | 8.05784 | 5.22826 | 5.73482 |
| Df | Methotrexate-derivative | 174121 | 9.30444 | 7 | 7 | 8.20389 | 7.08396 | 8.40302 | 8.43676 | 9.17605 | 7.16636 | 8.41607 | 7 | 7 | 9.3006 | 7.58677 | 7 | 7 | 7 | 8.22849 | 8.42881 | 8.38419 | 8.47891 | 9.00786 | 8.83944 | 9.35574 | 9.16642 | 8.81522 | 8.43389 | 7 | 7 | 8.02564 | 8.01409 | 7 | 9.37356 | 9.53297 | 8.32193 | 8.60156 | 8.34814 | 8.36548 | 7.27922 | 8.29104 | 7 | 9.15484 | 8.27356 | 7 | 7.46258 | 7 | 7.07734 | 7.73344 | 9.36061 | 8.11741 | 8.78663 | 8.4029 | 9.32014 | 8.0275 | 7 | 7.00763 | 8.60838 | 9.07879 | 7.03603 | 7 |
| Df | Trimetrexate | 352122 | 9.57802 | 9.15876 | 6 | 9.75136 | 8.54058 | 9.21564 | 9.54902 | 9.6242 | 8.44533 | 10 | 7.12288 | 7.70434 | 9.83297 | 8.92569 | 7.63232 | 7.68411 | 6.7433 | 9.28828 | 9.16115 | 9.50986 | 9.62218 | 9.70524 | 8.07956 | 9.75927 | 9.43447 | 9.35692 | 8.72695 | 7.51412 | 6.4375 | 9.16511 | 9.52762 | 8.13727 | 9.5366 | 9.93702 | 9.56955 | 9.38526 | 8.52181 | 9.38081 | 8.13974 | 8.48566 | 8.30609 | 9.09443 | 9.38537 | 8.01018 | 8.00300 | 6.58333 | 8.49672 | 7.54668 | 9.08474 | 8.37171 | 8.8261 | 7.74232 | 9.36161 | 9.1313 | 6 | 6.61976 | 9.41164 | 9.70254 | 6 | 7.10344 |
| Dr | Guanazole | 1895 | 2.42692 | 2.10760 | 2 | 2.40020 | 2 | 2.31299 | 2.48551 | 2.54983 | 2 | 2.37942 | 2 | 2 | 2.50988 | 2.30696 | 2.12437 | 2 | 2 | 2.40585 | 2.21332 | 2.71993 | 2.61408 | 2.34604 | 2.18103 | 2.18623 | 2 | 2 | 2 | 2 | 2 | 2.41223 | 2 | 2 | 2.67978 | 2.00809 | 2.49546 | 2.43929 | 2.11210 | 2.30725 | 2.34751 | 2.36494 | 2.11976 | 2.58616 | 2.72003 | 2 | 2 | 2.09265 | 2 | 2.29356 | 2.83147 | 2.4862 | 2.46959 | 2.59384 | 2.02016 | 2.24752 | 2 | 2 | 2 | 2.01818 | 2 | 2 |
| Dr | Hydroxyurea | 32065 | 3.13237 | 2.99799 | 2.60206 | 3.28275 | 2.60206 | 3.11337 | 3.25177 | 3.51307 | 3.16126 | 3.27833 | 2.60206 | 2.60206 | 3.43794 | 3.01482 | 3.04279 | 2.75592 | 3.07969 | 3.22669 | 3.28494 | 3.34084 | 3.44203 | 3.32759 | 3.06196 | 3.01565 | 2.93966 | 3.11303 | 3.05440 | 2.90703 | 2.60206 | 3.27225 | 2.86360 | 2.70457 | 4.34364 | 3.06002 | 3.74821 | 3.64461 | 3.29104 | 3.11327 | 3.10996 | 3.50609 | 2.93662 | 3.57237 | 3.9438 | 2.60206 | 2.6999 | 3.09308 | 2.70479 | 3.23689 | 4.81263 | 3.65985 | 3.41702 | 3.40762 | 3.03652 | 3.09959 | 2.60206 | 2.84771 | 2.68004 | 2.71005 | 2.75423 | 2.90398 |
| Dr | Pyrazoloimidazole | 51143 | 2.53092 | 2.55447 | 2 | 2.86021 | 2.08578 | 2.64052 | 2.73587 | 3.27825 | 2.42043 | 2.73216 | 2.519 | 2.35323 | 2.8376 | 2.42392 | 2.31896 | 2.34989 | 2.47365 | 2.79036 | 2.55127 | 3.37329 | 2.99364 | 2.61027 | 2.41211 | 2.49335 | 2.34619 | 2.39815 | 2.49816 | 2.32535 | 2.12674 | 2.77691 | 2.13616 | 2.25393 | 3.50623 | 2.42293 | 3.33369 | 3.04873 | 2.60847 | 2.66332 | 2.7241 | 3.36075 | 2.68929 | 3.02022 | 3.33539 | 2 | 2.17769 | 2.30808 | 2 | 2.43236 | 3.38347 | 2.81238 | 2.89557 | 3.11314 | 2.29612 | 2.51147 | 2 | 2 | 2.40495 | 2.36529 | 2.31468 | 2.48243 |
| Ds | Aphidicolin-glycinate | 303812 | 5.60448 | 4.22609 | 4.17397 | 4.92278 | 4.20564 | 5.39218 | 5.3408 | 6.08209 | 4.20099 | 5.75632 | 4.25742 | 4.16175 | 6.59204 | 5.51291 | 4.74585 | 4.2853 | 4.50422 | 5.67226 | 4.96995 | 6.39848 | 5.89215 | 5.11236 | 4.20774 | 5.74237 | 4.29038 | 4.27493 | 4.24192 | 4.15334 | 4.07502 | 5.61733 | 4.29384 | 4.20527 | 6.11453 | 4.72732 | 5.79659 | 5.77986 | 5.37017 | 5.06871 | 5.15817 | 6.14609 | 5.10373 | 5.7903 | 6.78618 | 4.13271 | 4.22613 | 4.93409 | 4.25164 | 4.6692 | 6.64649 | 5.53829 | 5.43828 | 5.34158 | 5.47976 | 5.8151 | 4.19479 | 4.14059 | 4.45874 | 4.24606 | 4.20240 | 4.35095 |
| Ds | Cyclocytidine | 145668 | 6.18865 | 5.74940 | 3 | 5.05939 | 5.33251 | 6.14469 | 6.56885 | 5.58418 | 3 | 6.54419 | 3 | 3 | 6.936 | 6.4417 | 4.62911 | 4.69032 | 3.03125 | 5.03438 | 5.08077 | 4.63978 | 4.48689 | 3.18939 | 3 | 6.42804 | 5.04706 | 3.53613 | 3 | 3 | 3 | 6.11788 | 3 | 3.92886 | 7 | 4.05010 | 7 | 7 | 5.31183 | 5.4426 | 4.72592 | 5.54746 | 3.51924 | 6.19033 | 6.51505 | 3 | 4.21226 | 3 | 3.3125 | 5.15468 | 5.91855 | 3.32738 | 6.22512 | 5.62113 | 5.7793 | 5.64545 | 4.13186 | 3 | 4.61338 | 5.19090 | 3 | 3 |
| Ds | Cytarabine (araC) | 63878 | 6.72091 | 5.04772 | 3.30103 | 4.97543 | 3.30103 | 6.66395 | 6.84092 | 5.90407 | 3.30103 | 6.89683 | 3.30103 | 3.30103 | 7.28399 | 6.86757 | 5.29016 | 5.50398 | 3.30103 | 5.44811 | 5.61782 | 4.92001 | 4.52392 | 3.30103 | 3.30103 | 6.79239 | 4.17941 | 3.30103 | 3.30103 | 3.30103 | 3.30103 | 6.17488 | 3.30103 | 3.30103 | 7.30103 | 3.79032 | 7.30103 | 7.07069 | 5.57136 | 5.70015 | 5.17500 | 6.01952 | 3.30103 | 6.37199 | 6.6703 | 3.30103 | 3.30103 | 3.30103 | 3.30103 | 5.04239 | 6.7785 | 3.30103 | 6.90969 | 5.9022 | 3.64191 | 5.66624 | 3.30103 | 3.30103 | 3.80586 | 5.34402 | 3.30103 | 3.30103 |
| Ds | Floxuridine (FUdR) | 27640 | 7.64789 | 5 | 5 | 6.72466 | 5.69080 | 6.50007 | 6.75048 | 7.4939 | 5.66747 | 8.01479 | 5 | 6.30618 | 9 | 7.47120 | 6.07354 | 5 | 7.27622 | 7.04903 | 7.85958 | 7.42273 | 8.51986 | 5.80968 | 9 | 7.04162 | 5 | 5.44657 | 5.00179 | 5.37468 | 5 | 6.8824 | 5.55271 | 5.71356 | 8.16918 | 6.07331 | 7.36838 | 7.47958 | 7.11399 | 6.87584 | 5.78971 | 7.35517 | 5.37615 | 7.24404 | 7.40108 | 5.34600 | 5.31585 | 5 | 5.76614 | 5.01651 | 6.72415 | 5.78958 | 8.41101 | 5.86844 | 6.56608 | 6.59263 | 5.18272 | 5 | 5.31103 | 5.87817 | 5.95868 | 6.12773 |
| Ds | Fluorouracil (5FU) | 19893 | 5.17358 | 4.76348 | 3.14811 | 4.89205 | 4.62036 | 4.96418 | 4.45553 | 4.87203 | 4.47167 | 5.71142 | 3.08975 | 4.53755 | 5.95765 | 4.91329 | 3.83138 | 3.94358 | 3.74457 | 4.31325 | 4.27906 | 4.26307 | 6.11428 | 5.14435 | 6.18083 | 5.34757 | 4.63865 | 5.19484 | 4.91658 | 4.38285 | 4.06634 | 4.80855 | 4.80629 | 3.60069 | 4.61415 | 4.79786 | 4.90571 | 5.40267 | 5.18378 | 4.6469 | 5.25616 | 5.37944 | 4.18324 | 4.90902 | 4.93894 | 3.39545 | 3.93559 | 3.56937 | 5.12169 | 3.57402 | 4.92005 | 5.35116 | 5.78298 | 4.63276 | 4.3777 | 5.11768 | 2.98539 | 3.63793 | 4.92597 | 5.01712 | 3.84829 | 4.20051 |
| Ds | Ftorafur | 148958 | 2.89280 | 2.54412 | 2.54356 | 3.45876 | 3.069 | 3.02694 | 2.75174 | 2.45055 | 2.30103 | 3.16014 | 2.30103 | 2.30103 | 3.43344 | 2.59041 | 2.30103 | 2.31467 | 2.30103 | 2.30103 | 2.47153 | 2.30103 | 3.29871 | 2.55372 | 2.74725 | 2.8318 | 2.82299 | 2.94298 | 2.73607 | 2.68514 | 2.38615 | 2.51692 | 2.61542 | 2.30103 | 3.02591 | 2.46324 | 2.30103 | 3.47247 | 3.03267 | 2.53195 | 2.30103 | 2.68492 | 2.95313 | 2.58514 | 2.48804 | 2.59725 | 2.40027 | 2.33301 | 2.89025 | 2.31524 | 2.9701 | 3.19385 | 3.24058 | 2.49039 | 2.5453 | 3.06055 | 2.30103 | 2.31318 | 2.86814 | 2.95273 | 2.3982 | 2.47403 |
| Ds | Thiopurine (6MP) | 755 | 6.50511 | 5.49234 | 5.4628 | 5.06814 | 3.12494 | 5.45534 | 6.31598 | 5.69606 | 5.71527 | 4.51592 | 3.42245 | 5.22851 | 5.28952 | 5.69637 | 5.45374 | 3.84429 | 5.05263 | 4.9104 | 5.41758 | 5.41256 | 5.59214 | 5.38249 | 5.49612 | 5.58918 | 5.23387 | 5.37636 | 5.19386 | 6.2343 | 5.32135 | 5.57177 | 5.05694 | 6.1041 | 5.85258 | 6.51100 | 5.78458 | 5.91989 | 5.37469 | 4.54161 | 4.25196 | 5.60413 | 4.71168 | 5.74014 | 5.25166 | 5.61536 | 5.21136 | 4.02661 | 5.38419 | 5.33129 | 5.60266 | 5.79485 | 5.73844 | 5.49431 | 5.40044 | 5.67505 | 5.14387 | 4.84125 | 5.72472 | 5.71686 | 3.73744 | 5.62409 |
| Rs | Acivicin | 163501 | 5.77186 | 5.53145 | 5.01723 | 5.61696 | 5.38153 | 5.36463 | 5.42935 | 5.53616 | 5.26537 | 6.06065 | 5.7643 | 5.1327 | 6.35303 | 5.73133 | 4.61560 | 5.36635 | 4.78846 | 5.6124 | 5.93384 | 5.88306 | 5.40708 | 6.05320 | 5.44780 | 6.17172 | 6.0526 | 6.09737 | 6.20903 | 5.49418 | 5.24703 | 5.62042 | 6.18311 | 4.88849 | 5.87239 | 5.54969 | 5.64261 | 6.1277 | 5.2777 | 5.33932 | 5.18978 | 5.52493 | 5.17099 | 5.43252 | 5.88543 | 5.48021 | 5.30456 | 5.20936 | 5.23901 | 5.21693 | 5.41132 | 5.41195 | 6.1825 | 5.33187 | 5.77048 | 5.64298 | 3.15132 | 5.48374 | 5.40939 | 5.41430 | 5.13073 | 5.17816 |
| Rs | Dichloroallyl-lawsone | 126771 | 5.73445 | 4.93593 | 4.47787 | 5.24437 | 4.53049 | 4.68857 | 4.53223 | 5.50025 | 4.93919 | 5.3694 | 4.32057 | 4.49998 | 5.85011 | 4.91386 | 4.38645 | 4.92362 | 4.38556 | 5.65223 | 4.65737 | 5.50286 | 4.9351 | 5.46529 | 4.52533 | 5.88475 | 4.94472 | 6.11214 | 5.16638 | 4.82572 | 4.83557 | 5.27107 | 5.15088 | 4.38942 | 5.62306 | 5.75954 | 5.76818 | 5.97673 | 4.66706 | 4.83481 | 4.42622 | 4.72057 | 4.4694 | 5.25492 | 4.91890 | 4.43224 | 4.6317 | 4.4623 | 4.58549 | 4.36643 | 5.70186 | 5.69263 | 5.04012 | 4.59653 | 5.11897 | 4.66573 | 4.89627 | 4.36419 | 4.77248 | 4.80301 | 4.74384 | 4.64153 |
| Rs | DUP785 (brequinar) | 368390 | 7.01260 | 4.7173 | 4.24016 | 6.02544 | 4.27468 | 4.33219 | 5.30897 | 6.74162 | 5.68278 | 6.57012 | 4.41729 | 4.23790 | 6.77327 | 6.61459 | 4.44199 | 5.94367 | 4.09546 | 6.65010 | 6.80305 | 6.90164 | 6.95128 | 6.42179 | 4.64532 | 7.08579 | 6.41149 | 7.30103 | 6.49457 | 5.63806 | 5.11752 | 6.66487 | 6.41194 | 4.1664 | 6.67233 | 6.96727 | 7.24419 | 6.36971 | 5.88314 | 5.82773 | 4.11638 | 6.50603 | 4.93075 | 6.94412 | 6.79082 | 4.23141 | 4.93957 | 4.57458 | 6.6854 | 4.04258 | 6.48854 | 6.56796 | 6.62721 | 5.79756 | 6.7825 | 6.45342 | 4.93628 | 4.68039 | 6.4308 | 6.53224 | 4.24132 | 4.43324 |
| Rs | L-Alanosine | 153353 | 6.50183 | 4.17836 | 3.97916 | 5.87325 | 4.55746 | 5.74004 | 4.7333 | 5.49962 | 4.55814 | 6.69606 | 4.37261 | 4.93023 | 6.21104 | 5.09236 | 3.92262 | 6.12219 | 4.13303 | 6.16836 | 5.1102 | 5.30594 | 4.99534 | 4.93298 | 4.86268 | 6.01394 | 4.76088 | 5.69211 | 6.47772 | 4.86278 | 4.70196 | 4.96919 | 6.51392 | 4.23751 | 5.02447 | 4.84449 | 4.70264 | 4.95236 | 5.79582 | 4.76705 | 5.42076 | 5.34162 | 4.5117 | 5.82158 | 5.55535 | 4.6448 | 4.27407 | 4.21586 | 4.58969 | 5.34080 | 5.05421 | 4.72634 | 5.97621 | 4.68916 | 5.40604 | 3.91701 | 3.30103 | 4.92065 | 5.21841 | 5.16233 | 5.03814 | 3.77851 |
| Rs | N-phosphonoacetyl-L-aspartic-acid | 224131 | 4.26232 | 2.43266 | 2.13720 | 4.09128 | 3.72188 | 2.40465 | 3.53903 | 4.09584 | 3.00622 | 4.35972 | 2.77004 | 2.14565 | 4.50995 | 3.53859 | 3.19879 | 4.27323 | 2.14318 | 4.41944 | 4.02261 | 4.40909 | 4.11716 | 3.788 | 2 | 4.66163 | 3.52409 | 3.79355 | 4.02574 | 3.26701 | 2.70757 | 4.06260 | 3.51502 | 2.00707 | 3.25341 | 4.14962 | 3.53773 | 3.64232 | 3.13094 | 3.14552 | 2.59499 | 3.46228 | 3.5824 | 4.35865 | 3.42173 | 3.05148 | 2.36859 | 2.53815 | 3.24 | 2 | 3.62549 | 3.59775 | 3.51706 | 3.1234 | 2.98354 | 3.06925 | 2.88859 | 2.38711 | 4.42470 | 3.89032 | 2.49313 | 2.38079 |
| Rs | Pyrazofurin | 143095 | 6.30103 | 3.32649 | 4.12461 | 4.07986 | 3.21584 | 4.90858 | 4.19091 | 5.229 | 4.10501 | 6.30103 | 5.05269 | 5.87538 | 6.30103 | 5.84099 | 4.53377 | 6.30103 | 3.99541 | 6.07484 | 5.57592 | 6.30103 | 4.85438 | 6.23666 | 4.48142 | 6.30103 | 6.30103 | 6.30103 | 5.20157 | 4.66584 | 4.29936 | 6.30103 | 6.2095 | 3.83487 | 6.30103 | 6.30103 | 6.30103 | 6.30103 | 5.49061 | 5.99359 | 4.14119 | 6.30103 | 5.26743 | 6.30103 | 6.30103 | 3.92181 | 2.77237 | 3.85711 | 5.22392 | 3.79381 | 6.30103 | 6.30103 | 6.13585 | 5.53985 | 5.76451 | 6.30103 | 5.07893 | 4.04065 | 4.77713 | 5.61102 | 3.73967 | 4.95232 |
| TU | Colchicine | 757 | 8 | 7.96804 | 8 | 8 | 8 | 7.91015 | 7.83928 | 8 | 8 | 7.36606 | 4 | 7.45196 | 7.61908 | 7.58254 | 8 | 7.49136 | 8 | 7.51822 | 7.35616 | 7.82864 | 8 | 7.59294 | 7.78318 | 7.78725 | 8 | 6.86853 | 8 | 7.80635 | 4.23888 | 7.60143 | 7.63886 | 7.71327 | 8 | 8 | 7.59855 | 7.64032 | 6.3833 | 7.28378 | 7.53718 | 7.11197 | 7.93464 | 7.34018 | 6.50809 | 4 | 4 | 7.51971 | 8 | 4.23913 | 8 | 8 | 7.94293 | 6.31205 | 7.63485 | 6.18133 | 6.46216 | NA | 8 | 8 | 7.68597 | 4.1059 |
| TU | Colchicine-derivative | 33410 | 8 | 7.69209 | 8 | 8 | 4.68783 | 8 | 8 | 8 | 8 | 8 | 4.60106 | 8 | 8 | 8 | 8 | 7.81179 | 8 | 8 | 8 | 8 | 8 | 8 | 7.85279 | 8 | 8 | 7.83213 | 8 | 8 | 4.82053 | 8 | 8 | 7.80667 | 8 | 8 | 8 | 7.61791 | 7.18312 | 8 | 8 | 7.623 | 8 | 8 | 7.35572 | 6.88196 | 7.62217 | 7.54204 | 8 | 5.41292 | 8 | 8 | 8 | 6.75706 | 7.80217 | 7.58687 | 7.96591 | 7.90031 | 8 | 8 | 6.39816 | 4.23409 |
| TU | Dolastatin-10 | 376128 | 9.46744 | 9.55623 | 9.86686 | 10.14080 | 9.40343 | 9.39299 | 9.54391 | 9.41605 | 9.88483 | 9.58517 | 9.34522 | 9.62983 | 9.91813 | 9.42366 | 8.99186 | 9.24121 | 9.53097 | 9.40405 | 9.25098 | 9.63744 | 9.57381 | 10.41775 | 9.41914 | 9.66765 | 9.71824 | 9.27939 | 10.35187 | 10.10561 | 8.93131 | 9.35249 | 8.99453 | 9.67338 | 9.61027 | 9.94006 | 9.43539 | 10.39973 | 8.1525 | 9.30591 | 9.51404 | 9.61565 | 9.50149 | 9.39105 | 9.1665 | 8.63025 | 9.61810 | 9.57971 | 9.83628 | 9.22508 | 10.18281 | 9.48221 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| TU | Halichondrin B | 609395 | 9.22689 | 9.18455 | 8.91911 | 9.60708 | 8.58832 | 8.82006 | 8.87605 | 9.33951 | 9.65686 | 8.76299 | 8.3016 | 8.85276 | 9.39354 | 8.88249 | 8 | 8.6299 | 9.41596 | 9.08609 | 8.38703 | 9.39814 | 9.21111 | 9.4252 | 8.68558 | 9.29498 | 9.31691 | 8 | 9.32385 | 9.54633 | 8.07318 | 8.61870 | 8.75539 | 8.57621 | 9.30166 | 9.34954 | 9.12667 | 9.29565 | 8.23487 | 8.46339 | 8.96882 | 9.29778 | 9.22981 | 8.74895 | 8.37139 | 8.14196 | 9.38587 | 8.62528 | 9.26606 | 8 | 9.64054 | 9.11584 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| TU | Maytansine | 153858 | 8.89226 | 7.92825 | 7.75543 | 8.67346 | 7.62191 | 8.28824 | 8.02157 | 8.1926 | 8.54702 | 8.11158 | 8.07762 | 7.85736 | 8.53303 | 8.43465 | 8.53999 | 7.96722 | 8.35101 | 8.23584 | 8.22889 | 8.42955 | 7.80326 | 7.85745 | 8.56881 | 8.05770 | 8.29415 | 8.49655 | 8.06568 | 8.38744 | 8.16592 | 8.42933 | 8.50536 | 8.51737 | 8.54954 | 8.47066 | 8.50724 | 8.56059 | 7.94022 | 8.17321 | 8.14981 | 7.91826 | 7.92195 | 7.88972 | 8.24989 | 7.65706 | 8.118 | 8.29476 | 8.0382 | 7.84928 | 7.95684 | 8.39787 | 8.41104 | 8.22242 | 8.53438 | 8.03179 | 8.22276 | 8.23925 | 8.00668 | 7.96357 | 9.67809 | 8.12274 |
| TU | Trityl-cysteine | 83265 | 6.06521 | 6.12073 | 6.38804 | 6.31625 | 4.87366 | 5.96167 | 6.50906 | 6.20064 | 6.41348 | 6.17539 | 6.22188 | 6.35204 | 6.35499 | 5.9125 | 4.87024 | 6.14242 | 6.09998 | 6.32619 | 6.01027 | 6.51686 | 6.46467 | 5.53633 | 6.29679 | 6.37742 | 6.25722 | 6.18253 | 6.19472 | 6.12371 | 5.36499 | 6.13494 | 5.84148 | 6.22957 | 6.32614 | 6.28903 | 6.11597 | 6.41318 | 4.66989 | 6.07724 | 5.93825 | 5.83873 | 6.34543 | 6.25772 | 4.78876 | 4.69146 | 6.06934 | 5.28722 | 6.31179 | 4.82797 | 6.36298 | 6.34543 | 6.33946 | 5.30845 | 6.15714 | 5.15213 | 6.4022 | 6.23198 | 6.66922 | 6.41196 | 5.93241 | 6.2413 |
| TU | Vinblastine-sulfate | 49842 | 9.60206 | 9.60206 | 9.52556 | 9.60206 | 9.15739 | 9.50469 | 9.48267 | 9.60206 | 9.60206 | 8.793 | 8.00402 | 9.14282 | 9.60206 | 9.59034 | 9.06456 | 9.15317 | 9.60206 | 9.60206 | 9.13841 | 9.60206 | 9.60206 | 9.60206 | 9.21101 | 9.60206 | 9.60206 | 7.55309 | 9.60206 | 9.60206 | 6.405 | 8.89731 | 8.9645 | 9.60206 | 9.46722 | 9.60206 | 9.54935 | 9.60206 | 6.83573 | 9.11524 | 8.6368 | 8.29125 | 9.20294 | 9.36049 | 8.03202 | 7.77269 | 9.49692 | 9.31316 | 9.60206 | 5.60395 | 9.60206 | 9.48665 | 9.60206 | 6.55900 | 9.60206 | 9.60206 | 9.26707 | 9.60206 | 9.60206 | 9.60206 | 9.60206 | 5.60206 |
| TU | Vincristine-sulfate | 67574 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 6.77781 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 6.12865 | 7 | 7 | 7 | 7 | 7 | 7 | 4.73333 | 7 | 7 | 7 | 3.97224 | 7 | 7 | 7 | 5.9849 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 3.68243 |
| TU | Taxol (Paclitaxel) | 125973 | 7.5404 | 7.31477 | 7.2204 | 7.94079 | 7.31826 | 7.46123 | 7.46684 | 7.55137 | 7.81547 | 7.40715 | 6.53323 | 7.39313 | 7.8351 | 7.2008 | 6 | 7.30643 | 8.20873 | 7.57363 | 7.53196 | 7.05661 | 7.71349 | 8.03478 | 7.55095 | 8.207 | 7.51153 | 6.28193 | 7.89692 | 7.54343 | 6 | 7.50907 | 7.45607 | 7.37271 | 7.48643 | 7.51623 | 7.47477 | 7.63082 | 6 | 7.42389 | 6.55093 | 6.2547 | 7.34341 | 7.34083 | 6.12428 | 6.62953 | 7.10235 | 7.29690 | 7.65835 | 7.43593 | 7.74642 | 8.30086 | 7.81158 | 6 | 7.40785 | 7.40306 | 7.22595 | 7.8056 | 8.3025 | 8.36492 | 7.42430 | 7.01054 |
| TU | Taxol analog | 600222 | 5.89147 | 4.93667 | NA | 5.92692 | 5.25225 | 5.77424 | 5.95925 | 5.68789 | NA | 5.57666 | 4.73063 | 5.62239 | 6.34323 | 5.71705 | 4.89772 | 5.33702 | 5.5886 | 5.75162 | 5.34978 | 5.42426 | 6.21224 | 6.45442 | 5.7164 | 6.26611 | 6.01464 | 4.4147 | 6.15099 | 5.72429 | 4.1 | 5.38306 | 6.11835 | 5.6214 | 6.12767 | 6.17340 | 5.71146 | 4.96912 | 4.07642 | 5.7222 | 7.00147 | 4.04948 | 5.59471 | 5.37237 | 4.93181 | 5.00287 | 5.37645 | 5.95165 | 5.99085 | 5.78376 | 6.44137 | 6.46094 | 6.61223 | 4 | 5.63689 | 5.58614 | 5.92441 | 5.95414 | 6.81416 | 6.56681 | NA | 6.08473 |
| TU | Taxol analog | 656178 | 6.0763 | 5.59546 | 6.43483 | 5.18157 | NA | 6.06121 | 5.58677 | 6.29385 | 6.19612 | 5.41884 | 5.25006 | 5.37564 | 5.99222 | 5.21819 | 4.64549 | 5.48141 | 6.29532 | 6.08248 | 5.40136 | 5.27445 | 6.3822 | 6.41489 | 5.7643 | 6.43118 | 6.34926 | 4.60806 | 6.25329 | 6.34279 | 4.04228 | 5.50503 | 5.72572 | 6.1152 | 6.34251 | 6.20816 | 6.11956 | 5.97461 | 4.33603 | 5.66148 | 5.23541 | 4.60529 | 4.60248 | 5.53806 | 4.29106 | 5.0701 | 6.16458 | 4 | 6.36278 | 5.40399 | 6.3868 | 6.28518 | 6.33429 | 4 | 6.05477 | 5.47463 | 5.37833 | 6.59804 | 6.74527 | 6.78302 | 5.89815 | 4 |
| TU | Taxol analog | 658831 | NA | 5.39625 | NA | 5.72202 | 5.56943 | 5.43434 | 5.63508 | 5.44698 | 6.60979 | 5.13997 | 4.18855 | NA | 6.12148 | 5.29661 | 4.60888 | 5.30856 | 6.83448 | 5.78426 | 5.63449 | 4.67309 | 6.30556 | 5.92260 | 5.79462 | 6.28665 | 4.79446 | 4 | 5.91802 | 6.15123 | 4 | 5.19700 | 5.39930 | 5.51663 | 5.80515 | 6.01454 | 5.61066 | 5.61769 | 4.11966 | 5.45114 | 4.59289 | NA | 5.70302 | 5.30719 | 4.04983 | 4.19916 | 4 | 4 | 6.17695 | 4.68452 | 6.26579 | 6.31322 | 5.99074 | 4 | 5.89119 | 5.54032 | 4.17049 | 6.70267 | 6.69468 | 7.10817 | 5.58056 | 5.75534 |
| TU | Taxol analog | 661746 | 7.10202 | 6.33597 | 6.84277 | 6.92968 | 6.44012 | 6.81908 | 6.84956 | 7.11943 | NA | 7.12352 | 5.99168 | NA | 7.45761 | 6.91077 | 5.61856 | 6.62346 | 7.01548 | 7.08537 | 6.79414 | 5 | 7.54977 | 7.55628 | 7.17515 | 7.69729 | 7.29741 | 6.53541 | 6.14788 | 6.91202 | 5.62368 | 7.18738 | 6.44209 | 6.38003 | 7.43458 | 7.44349 | 7.36928 | 6.77202 | 6.01217 | 6.84078 | 6.78584 | 6.28019 | 7.23806 | 7.06895 | 6.25587 | 6.52278 | 7.0986 | 6.0543 | 7.10321 | 6.78274 | 7.57033 | 7.62702 | 7.53775 | 5.8048 | 7.08267 | 6.57426 | 6.67724 | 7.7308 | 7.93265 | 7.87735 | 6.71268 | 6.93157 |
| TU | Taxol analog | 664402 | 7.26554 | 6.78336 | 7.13273 | 7.36189 | 6.97996 | 7.12514 | 7.00777 | 7.31398 | 7.515 | 7.09151 | 5.72811 | 6.63526 | 7.01955 | 6.66792 | 6.27155 | 5.62906 | 7.25625 | 6.86448 | 6.77508 | 6.53687 | 7.23283 | 7.383 | 7.15367 | 7.49164 | 7.33840 | 5.85094 | 7.6548 | NA | 5 | 7.17479 | 7.32195 | 7.75078 | 7.40051 | 7.28721 | 7.34341 | 7.39269 | 6.40253 | 7.09274 | NA | 5.80751 | 6.7263 | 6.49006 | 5.47907 | 6.42017 | 6.89647 | 6.36936 | 7.35268 | 6.29363 | 7.74469 | 7.51633 | 7.50852 | 5 | 7.24806 | 6.97424 | 5.22706 | 7.31383 | 7.80047 | 7.65716 | 6.46598 | 5.86679 |
| TU | Taxol analog | 664404 | 8.20825 | 7.87044 | 8.62128 | 8.59956 | 8.49755 | 8.49423 | 6.63268 | 8.3225 | 8.60832 | 8.19629 | 6.36887 | 7.51747 | 8.47619 | 7.65576 | 6.29416 | 6.21709 | 9 | 8.05593 | 8.31308 | 7.35175 | 8.69143 | 9 | 8.51807 | 8.77818 | 8.53872 | 6.26206 | NA | NA | 5 | 8.26056 | 8.54469 | 8.36438 | 8.70283 | 8.74578 | 8.82827 | 8.76639 | 5.6058 | 8.28119 | 6.60758 | 6.42333 | 7.85049 | 7.42298 | 6.80337 | 7.41728 | 7.82412 | 7.41997 | 8.75 | 6.64639 | 8.95415 | 9 | 9 | 5.0648 | 8.55116 | 7.6339 | 5 | 8.74533 | 9 | 7.04284 | 6.60457 | 8.39867 |
| TU | Taxol analog | 666608 | 7.05182 | 6.74564 | 7.44088 | 7.16436 | 6.87835 | 7.03956 | 7.3322 | 7.33370 | 7.28139 | 7.00068 | 5.27205 | NA | 7.15104 | 7.29553 | 5.64686 | 6.55464 | 7.22648 | 7.15991 | 7.62162 | 6.51730 | 7.47314 | 7.34323 | 7.3401 | 7.57632 | 7.51486 | 5.81272 | 7.29122 | 7.44055 | 6.07471 | 7.04119 | 7.33056 | 7.60493 | 7.54233 | 7.53694 | 7.57890 | 7.62073 | 5.62052 | 7.16719 | 6.33074 | 5.79757 | 6.66015 | 6.81474 | 5.82082 | 6.29625 | 7.08286 | NA | 7.10433 | 6.81380 | 7.97038 | 7.64124 | 8.01490 | 4.80387 | 7.25661 | 6.99832 | 7.32169 | 7.71814 | 8.00260 | 7.99388 | 7.09264 | 5.6651 |
| TU | Taxol analog | 671867 | 8.08787 | 6.75261 | 7.09498 | 7.96907 | 5.75130 | 7.58413 | 8.14046 | 7.88813 | 8.03712 | 7.71344 | 4.90309 | 7.81966 | 8.11822 | 7.74308 | 7.83079 | 7.48713 | 6.39574 | 7.86461 | 6.69385 | 7.5684 | 8.52614 | 8.4748 | 7.5254 | 8.42185 | 8.19831 | 6.57152 | 8.13637 | 8.90309 | 4.99058 | 7.84177 | 8.45908 | 7.82128 | 8.30223 | 8.55988 | 8.32392 | 8.26608 | 6.07123 | 7.41405 | NA | 5.73650 | 7.47976 | 7.75407 | 6.38377 | 6.82186 | 7.59763 | 7.62815 | 7.88552 | 8.13132 | 8.90309 | 8.33964 | 8.58643 | 5.51773 | 7.77608 | 7.06217 | 7.37040 | 8.2614 | 8.64641 | 8.77122 | 7.87269 | 7.16919 |
| TU | Taxol analog | 671870 | 6.19954 | 5.77948 | 5.62977 | 6.39080 | 5.80859 | 6.02285 | 6.26026 | 5.91376 | 6.25482 | 5.77012 | 5.13149 | 5.87962 | 6.09078 | 6.48730 | 5.67064 | 5.89586 | 6.11515 | 6.44204 | 5.92129 | 5.93626 | 6.3641 | 6.88481 | 6.10721 | 6.75068 | 6.45517 | 5.19526 | 6.78677 | 6.489 | 5.42250 | 5.85101 | 6.34826 | 5.99059 | 6.42486 | 6.67505 | 6.38617 | 6.86686 | 5.19049 | 5.67499 | 6.35327 | 5.27216 | 6.28041 | 5.78596 | 5.61163 | 5.56741 | 6.14448 | 5.76607 | 6.86818 | 6.07365 | 7.18058 | 7.04364 | 6.94807 | 4.60206 | 6.58941 | 5.73432 | 5.49781 | 6.65394 | 7.15514 | 7.19923 | 6.16301 | 4.60206 |
| TU | Taxol analog | 673187 | 6.89012 | 6.92287 | 7.2255 | 6.93487 | 5.74095 | 6.38539 | 6.37589 | 6.55803 | 6.50957 | 6.28553 | 5.05583 | 6.26731 | 6.78511 | 6.17019 | 5.63388 | 6.46311 | 6.87259 | 6.90302 | 6.73234 | 5.83950 | 7.44779 | 7.40575 | 6.52751 | 7.22856 | 6.83508 | 4.82067 | 7.07868 | 7.21319 | 4.64905 | 6.56354 | 6.60073 | 6.54233 | 7.30106 | 7.10776 | 6.94286 | 7.09155 | 4.73657 | 6.51212 | 5.41938 | 4.84472 | 6.16714 | 5.93725 | 5.09760 | 5.0751 | 6.37714 | 6.36841 | 6.94315 | 6.47679 | 7.64407 | 7.72437 | 7.4682 | 4.60206 | 6.9207 | 6.17039 | 5.33925 | 7.21621 | 7.78192 | 7.89842 | 5.55091 | 5.68915 |
| TU | Taxol analog | 673188 | 8.08245 | 7.89708 | 7.22394 | 7.63833 | 5.02336 | 6.90724 | 7.25259 | 7.70011 | 7.93717 | 7.08571 | 5.70049 | 7.45251 | 7.88136 | 6.90081 | 5.61381 | 7.51378 | 7.72366 | 8.06693 | 7.03164 | 6.7754 | 7.99207 | 8.16929 | 7.96902 | 8.21603 | 8.18677 | 5.83319 | 7.94643 | 8.25413 | 5.18171 | 7.74166 | 7.63272 | 7.79929 | 8.08709 | 8.06627 | 7.83586 | 7.9668 | 5.22839 | 6.27731 | 6.69486 | 5.41758 | 7.08988 | 7.0764 | 6.09594 | 6.38063 | 7.39885 | 6.96738 | 7.96556 | 7.65316 | 8.3288 | 8.22803 | 8.47625 | 5.00744 | 7.95112 | 7.40277 | 6.65979 | 8.27054 | 8.60206 | 8.60206 | 6.19446 | 8.03094 |
| P90 | Geldanamycin | 330500 | 6.49676 | 6.69570 | 5.86070 | 6.39595 | 6.54099 | 6.95659 | 5.87997 | 6.65153 | 6.77864 | 5.9742 | 5.21252 | 5.68285 | 6.62567 | 6.47161 | 6.64979 | 5.62166 | 6.29445 | 6.32852 | 5.91886 | 5.91151 | 6.47945 | 6.79676 | 5.9849 | 6.51829 | 6.94688 | 5.20503 | 6.70348 | 6.65343 | 5.27189 | 5.81579 | 6.4838 | 6.47825 | 6.76101 | 6.93756 | 6.94156 | 6.82705 | 5.08144 | 6.42042 | 5.17247 | 5.1754 | 6.50001 | 5.88336 | 5.16363 | 5.39427 | 6.48094 | 5.31349 | 7.09431 | 5.94074 | 7.12295 | 6.65539 | 6.82455 | 5.14253 | 6.63768 | 6.52111 | 6.68312 | 5.83921 | 7.00076 | 6.72567 | NA | 6.68009 |
| Uk | 3-Hydropicolinaldehyde-thiosemicarbazone | 95678 | 5.91558 | 5.58291 | 4.51154 | 5.94895 | 5.34665 | 6.26013 | 6.37079 | 6.19573 | 5.7595 | 5.51115 | 5.58851 | 5.54859 | 5.87571 | 5.91586 | 6.19273 | 5.57352 | 5.5604 | 5.65406 | 5.87705 | 6.18609 | 6.44154 | 5.62079 | 5.47385 | 5.62467 | 5.76855 | 5.75282 | 5.52069 | 5.73950 | 5.48891 | 6.07993 | 5.60530 | 5.34447 | 6.09937 | 5.65897 | 6.05118 | 6.38159 | 5.9262 | 5.96149 | 5.62905 | 6.0343 | 6.12691 | 6.48526 | 6.59117 | 5.35339 | 5.63184 | 5.46868 | 5.47619 | 5.54003 | 5.98641 | 6.02102 | 6.07347 | 6.08764 | 5.99326 | 6.31448 | 5.38168 | 4.46012 | 5.87514 | 5.77216 | 5.80064 | 5.46141 |
| Uk | 5-Hydroxypicolinaldehyde-thiosemicarbazone | 107392 | 5.33372 | 5.16952 | 4.05830 | 5.17867 | 4.67257 | 5.05151 | 5.28299 | 5.42626 | 5.39486 | 4.38844 | 4.91604 | 5.07835 | 4.6335 | 5.30254 | 5.20492 | 4.85704 | 4.77045 | 5.21116 | 5.27544 | 4.55962 | 5.50939 | 4.54834 | 4.89141 | 5.14995 | 4.87857 | 5.0115 | 5.07914 | 5.54052 | 5.08184 | 5.46327 | 4.69971 | 4.59645 | 5.70147 | 5.20901 | 5.45574 | 5.81179 | 5.01840 | 5.24693 | 4.48402 | 4.97805 | 5.09366 | 5.3308 | 5.73748 | 3.94742 | 4.66087 | 4.62997 | 4.97821 | 4.52728 | 5.40113 | 5.02751 | 5.42617 | 5.37943 | 5.13498 | 5.48967 | 4.62028 | 3.51857 | 5.05652 | 5.03262 | 4.20976 | 5.29828 |
| Uk | Inosine-glycodialdehyde | 118994 | 4.00344 | 3.49401 | 3.454 | 3.41959 | 3.41721 | 3.6028 | 3.27514 | 3.40504 | 3.83150 | 3.11142 | 3.43446 | 3.37124 | 3.17994 | 3.18566 | 3.58255 | 3.15291 | 3.21139 | 3.12068 | 3.36391 | 3.16562 | 3.16351 | 3.37335 | 3.40790 | 3.80382 | 3.85961 | 4.15802 | 3.47577 | 3.82694 | 3.47425 | 3.4298 | 3.77194 | 3.20656 | 4.10823 | 4.11276 | 3.97891 | 3.79125 | 3.36965 | 3.53049 | 3.15177 | 3.42879 | 3.54591 | 3.22636 | 3.29524 | 3.23599 | 3.42732 | 3.23693 | 3.48028 | 3.20905 | 4.47812 | 4.13468 | 4.12184 | 3.3559 | 3.40817 | 3.63009 | 3.93023 | 3.26803 | 3.62991 | 4.03794 | 3.36323 | 4.06288 |
