Testing Information

Testing Status of Agents at NTP

Prevention 4 (Melatonin + curcumin)

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http://ntp.niehs.nih.gov/go/TS-M000042

CASRN: MEL+CURCUMIN

Formula: C21 H20 O6

Synonyms/Common Names:

  • MELATONIN + CURCUMIN (PREVENTION 4)

Secondary:

  • 458-37-7 - Curcumin
  • 73-31-4 - Melatonin
  • 73-31-4 - Prevention 1 (Melatonin)
  • 73-31-4 - Prevention 2 (Melatonin)
  • 73-31-4 - Prevention 3 (Melatonin)
  • 73-31-4 - Prevention 6 (Melatonin)
  • 458-37-7 - Prevention 4 (Curcumin)
  • 73-31-4 - Prevention 4 (Melatonin)
  • 73-31-4 - Prevention 5 (Melatonin)

Known Uses:

DYEING COTTON, WOOL, SILK; COLORING OILS & WAXES; BORON INDICATOR; STAIN IN MICROSCOPY; ALKALI INDICATOR; PREPARING CURCUMA PAPER; FOOD DYE; ANALYTICAL AGENT. WILL BE USED IN SPECIAL STUDY TO INVESTIGATE THE DIETARY INTERVENTION TO PREVENT/DELAY MAMMARY CANCER.

Short-Term Toxicity

  • 26-WEEK (Dosed-Feed)  (C20010E) Completed 
    • Mice: MMTV/NEU (Tg.Nk)
    • Dose: (MEL 0.028% OR 280 PPM) + (CUR 0.50% OR 5000 PPM)