NLM Gateway
A service of the U.S. National Institutes of Health
Your Entrance to
Resources from the
National Library of Medicine
    Home      Term Finder      Limits/Settings      Search Details      History      My Locker        About      Help      FAQ    
Skip Navigation Side Barintended for web crawlers only
 

Report of two cases of MDR-MTB pneumonia in non-immunocompromised health care workers (HCWs) at a New York City AIDS center.

Kwan R, Chiliade P, Sharp V; International Conference on AIDS.

Int Conf AIDS. 1993 Jun 6-11; 9: 329 (abstract no. PO-B07-1162).

Spellman Center for HIV-Related Disease, St. Clare's Hospital, New York, NY.

CASE #1: 24-year old HIV(-) male, with no significant past medical history and a negative PPD on 10/1/90. Had numerous contacts with HIV(+) MDR-MTB patients. Subject in good health until 4/91 when the following symptoms appeared: malaise, occasional dry cough, left pleuritic chest pain, and weight loss. New objective findings: PPD conversion, chest x-ray--Gohn's complex left upper lobe and hilum; sputum smear (+) few AFB, culture positive for MTB complex. Sensitivity: Resistant to INH/Rif/Sm/Eth/Km. Treatment: INH/Rif for one year with resolution of symptomatology and infiltrate after two months of therapy. CASE #2: 33 year-old HIV(-) male with no significant past medical history. PPD negative in spite of two previous BCG vaccinations. Had numerous contacts with HIV(+) MDR-MTB patients. Subject in good health until 2/92 when the following symptoms appeared: mild dry cough and pleuritic chest pain; PPD(-); chest x-ray showed left upper lobe infiltrate; sputum smear negative for AFB; culture positive for MTB complex. Sensitivity: Resistant to INH/Rif/Sm/Km/Cm/Ethionamide. Treatment: INH/Rif 5/92 to 7/92; changed to Eth/PZA/Oflox/PAS 7/92 to present with resolution of symptomatology and radiographic improvement. CONCLUSION: Active disease with MDR-MTB can occur in healthy non-immunocompromised individuals. Physicians treating HCWs with pulmonary disease must be aware of the prevalence of MTB in the patient population served by these HCWs, as well as the resistance pattern of MTB in the population.

Publication Types:
  • Meeting Abstracts
Keywords:
  • Acquired Immunodeficiency Syndrome
  • HIV Infections
  • HIV Seropositivity
  • Health Personnel
  • Humans
  • Immunocompromised Host
  • Male
  • New York City
  • Pneumonia
  • Pneumonia, Pneumocystis
  • Prevalence
  • Sputum
  • immunology
  • methods
  • organization & administration
Other ID:
  • 93334687
UI: 102204061

From Meeting Abstracts




Contact Us
U.S. National Library of Medicine |  National Institutes of Health |  Health & Human Services
Privacy |  Copyright |  Accessibility |  Freedom of Information Act |  USA.gov