[Influence of compatibility on content of berberine in Maxingganshi decoction]
[Article in Chinese]
Guangdong Provincial Health Care Hospital for Women and Children, Guangzhou 510010, China.
OBJECTIVE: To set up the quantitative method of herberine in decoctions prepared from various combinations of Maxingganshi decotion by HPLC and to determine the change of general contents in different decoction. METHODS: The study was designed by L8 (2(7)) orthogonal and to determine the change of general contents in different decoction by HPLC. RESULTS: In full formula remove Glycyrrhiza uralensis group, the contents of L-ephedrine, d-pseudephedrine and the amygdaloside cut down significantly. In full formula remove armeniacae semen group, the content of glycyrrhetic acid cut down significantly. Four chemical composition in full formula group had higher contents. CONCLUSION: Armeniacae semen can decrease the content of L-ephedrine, D-pseudephedrine. Glycyrrhiza uralensis can help decoctum amygdaloside and armeniacae semen can help decoctum glycyrrhizic acid.
PMID: 17727071 [PubMed - indexed for MEDLINE]