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HIV protease HIVSDB Homology Searches Using Chem-BLAST NIST
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HIVSDB Homology Searches Using Chem-BLAST

NIST

This page shows all the inhibitors which have at least one chosen (Chosen) group in common. When the query has resulted in several PDBID's, additional group may be chosen by clicking another fragment | ?. PubMed abstract may be viewd if available.

Current Page :1 Result pages :|1 |2 |3 |4 |5 |6 |7 |8 |9

View Inhibitor 1B6L1B6L.
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease.

Martin JL, Begun J, Schindeler A, Wickramasinghe WA, Alewood D, Alewood PF, Bergman DA, Brinkworth RI, Abbenante G, March DR, Reid RC, Fairlie DP.


Biochemistry. 1999 Jun 22;38(25):7978-88. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1B6L. (Click another fragment to search inhibitors using an additional fragment)
tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1-methylpiperidine-2-carbaldehyde 1-methylpiperidine-2-carbaldehyde 4-[4-(2-amino-3-hydroxypropyl)phenoxy]butanal 4-[4-(2-amino-3-hydroxypropyl)phenoxy]butanal 3-amino-4-oxobutanamide 3-amino-4-oxobutanamide 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 
View Inhibitor 1C6X1C6X.
An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.

Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC.


Acta Crystallogr D Biol Crystallogr. 2000 Apr;56 ( Pt 4):381-8. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1C6X. (Click another fragment to search inhibitors using an additional fragment)
1-methylpiperazine-2-carbaldehyde 1-methylpiperazine-2-carbaldehyde 2-(2-methylphenyl)succinaldehyde 2-(2-methylphenyl)succinaldehyde 2-amino-3-methylcyclopentanol 2-amino-3-methylcyclopentanol 3 3'-chloro-4-methyl-1,2'-bipiperazine-5'-carbaldehyde tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 
View Inhibitor 1C6Y1C6Y.
An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.

Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC.


Acta Crystallogr D Biol Crystallogr. 2000 Apr;56 ( Pt 4):381-8. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1C6Y. (Click another fragment to search inhibitors using an additional fragment)
1-amino-1H-inden-2-ol 1-amino-1H-inden-2-ol 1-methyl-4-(2-pyridin-3-ylethyl)piperazine-2-carbaldehyde 1-methyl-4-(2-pyridin-3-ylethyl)piperazine-2-carbaldehyde 2-(2-methylphenyl)succinaldehyde 2-(2-methylphenyl)succinaldehyde tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 
View Inhibitor 1C6Z1C6Z.
An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.

Munshi S, Chen Z, Yan Y, Li Y, Olsen DB, Schock HB, Galvin BB, Dorsey B, Kuo LC.


Acta Crystallogr D Biol Crystallogr. 2000 Apr;56 ( Pt 4):381-8. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1C6Z. (Click another fragment to search inhibitors using an additional fragment)
2-methyldecahydroisoquinoline-3-carbaldehyde 2-methyldecahydroisoquinoline-3-carbaldehyde 3-amino-4-oxobutanamide 3-amino-4-oxobutanamide PHE PHE quinoline-2-carbaldehyde quinoline-2-carbaldehyde tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 
View Inhibitor 1C701C70. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1C70. (Click another fragment to search inhibitors using an additional fragment)
1,4-dimethylpiperazine-2-carbaldehyde 1,4-dimethylpiperazine-2-carbaldehyde 1-amino-1H-inden-2-ol 1-amino-1H-inden-2-ol 1-benzofuran 1-benzofuran 2-(2-methylphenyl)succinaldehyde 2-(2-methylphenyl)succinaldehyde tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 
View Inhibitor 1FB71FB7.
Crystal structure of an in vivo HIV-1 protease mutant in complex with saquinavir: insights into the mechanisms of drug resistance.

Hong L, Zhang XC, Hartsuck JA, Tang J.


Protein Sci. 2000 Oct;9(10):1898-904. Abstract
Related 2-D structures, Cellular data, Anti-HIV enzyme data, References
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Fragments of 1FB7. (Click another fragment to search inhibitors using an additional fragment)
2-methyldecahydroisoquinoline-3-carbaldehyde 2-methyldecahydroisoquinoline-3-carbaldehyde 3-amino-4-oxobutanamide 3-amino-4-oxobutanamide PHE PHE quinoline-2-carbaldehyde quinoline-2-carbaldehyde tert-butylamineThis residue has been selected, You may select one other residue shown in this row tert-butylamine 1. :Structure, links & more 2. :Abstract, text data & more
End of this inhibitor 

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