Chemical Sampling Information
	Butylamine
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: 1-Aminobutane; n-Butylamine OSHA IMIS Code Number: 0470 Chemical Abstracts Service (CAS) Registry Number: 109-73-9 NIOSH, Registry of Toxic Effects (RTECS) Identification Number: EO2975000 Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1125 132 [27 KB, PDF] NIOSH Pocket Guide to Chemical Hazards, n-Butylamine: chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 5 ppm, 15 mg/m3 Ceiling; Skin OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 5 ppm, 15 mg/m3 Ceiling; Skin OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 5 ppm, 15 mg/m3 Ceiling; Skin American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 5 ppm, 15 mg/m3 Ceiling; Skin (TLV listed under n-Butylamine) National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 5 ppm, 15 mg/m3 Ceiling; Skin (REL listed under n-Butylamine) Health Factors NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 300 ppm Potential symptoms: Eye, nose, throat irritation; cough, sore throat, shortness of breath, pulmonary edema (may be delayed); dizziness; headache; skin flush, burns, blisters, dermatitis; loss of vision; INGES. ACUTE: Burning sensation, abdominal pain, nausea, vomiting, diarrhea, shock or collapse; SKIN ABS. Health Effects: Irritation-Eye, Nose, Throat, Skin---Marked (HE14); Pulmonary edema (HE11) Affected organs: Eyes, skin, respiratory system Notes: Vapor/air mixtures of butylamine may be explosive. Butylamine is considered to be generally recognized as safe when used as a flavoring agent (Flavor and Extract Manufacturers Association number 3130; Joint FAO/WHO Expert Committee on Food Additives number 1582). In two different strains of mice, sensory irritation occurred at a lower concentration of n-butylamine (121-246 ppm) than did pulmonary irritation (300-362 ppm). Date Last Revised: 03/13/2007 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: n-Butylamine. International Chemical Safety Cards (WHO/IPCS/ILO): n-Butylamine. Pohanish, R.P. (editor): Butyl Amines. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 402-404. Vinggard, A.M., Nielsen, G.D. and Fries, A.S.: Sensory and pulmonary irritation of inhaled n-butylamine in CF-1 and NMRI mice. Lab. Anim. 23(1): 1-6, 1989. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Coated Silica Gel Tube (150/75 mg sections, 20/40 mesh); Coating is H2SO4. analytical solvent: (50:50) Methanol:Water minimum volume: 2 Liters   maximum volume: 100 Liters   maximum flow rate: 1.0 L/min (Ceiling) current analytical method: Gas Chromatography; GC/FID method reference: NIOSH Analytical Method (NIOSH 2012) [21 KB, PDF] method classification: Fully Validated note: OSHA personnel may obtain sampling tubes from SLTC. All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.