Taxon Scaffold Gene1 Gene2 Consecutive Sep Code Strand1 Strand2 GNScore GNWithin GNAll GNMinus CAI CAI.Alm CBI COG COGanno COGfun Annotation nCAI nCAI.Alm nCBI nCOG nCOGanno nCOGfun nAnnotation MI HK CAIdsqr CAIdxdy CAIlogpratio CAIdxdyR CAIdsqrR COGsim N1 N2 forward forwardplus sumBias same bbfGNScore bbfGNMinus bbfGNWithin bbfGNAll bbfHK bbfMI bbfCAIdxdyR bbfCAIdsqrR COGsimClass cfCOG pSame 13773 129 181994 181995 1 -3 Convergent + - 0.000000 0 0.000000 -0.07232066 1.335192 2.921130 1.0080980 2419 Uncharacterized conserved protein S conserved hypothetical protein 1.442419 3.054999 1.0304610 - - - paREP1 5.285113e-02 1 1.149767e-02 1.042750e-03 -1.155778e-03 -9.842096e-03 7.507564e-01 2 1 FALSE FALSE 1 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.8555544 0.5187177 0.4596276 U 0.4686274 0.5573725 13773 129 181995 181996 1 44 Same - - 0.000000 0 0.000000 -0.07232066 1.442419 3.054999 1.0304610 - - - paREP1 1.377219 3.027830 1.0338433 2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog E peptidase, putative 2.630109e-02 1 4.251110e-03 6.656162e-04 4.228767e-02 -7.006088e-03 3.845332e-01 1 11 TRUE FALSE 0 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.7172240 0.5194147 0.5154995 U 0.4686274 0.5573725 13773 129 181996 181997 1 243 Divergent - + 0.000000 0 0.000000 0.00000000 1.377219 3.027830 1.0338433 2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog E peptidase, putative 1.564707 3.533702 1.1559862 4938 Uncharacterized conserved protein S conserved within P. aerophilum 0.000000e+00 0 3.515206e-02 -8.405023e-03 -5.890030e-02 -4.820189e-01 1.961719e+00 11 0 TRUE FALSE -1 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4082009 0.4087037 U 0.4686274 0.6162291 13773 129 181997 181998 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.564707 3.533702 1.1559862 4938 Uncharacterized conserved protein S conserved within P. aerophilum 1.672620 3.548649 0.9656766 - - - hypothetical protein 0.000000e+00 0 1.164519e-02 2.506830e-02 4.055232e-01 7.555479e-01 2.622262e-02 0 0 FALSE FALSE 0 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7685196 0.6348800 U 0.4686274 0.6162291 13773 129 181998 181999 1 173 Convergent + - 0.000000 0 0.000000 0.00000000 1.672620 3.548649 0.9656766 - - - hypothetical protein 1.536064 3.277354 1.1431629 - - - hypothetical protein 0.000000e+00 0 1.864766e-02 1.873157e-02 1.336710e-01 6.669614e-01 6.492132e-02 0 0 FALSE FALSE 1 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7426382 0.6191240 U 0.4686274 0.6162291 13773 129 181999 182000 1 27 Same - - 0.000000 0 0.000000 0.00000000 1.536064 3.277354 1.1431629 - - - hypothetical protein 1.317406 2.858902 1.0053560 602 Organic radical activating enzymes O coenzyme PQQ synthesis protein, conjectural 0.000000e+00 0 4.781143e-02 -1.134484e-02 -8.452485e-02 -6.304743e-01 2.562948e+00 0 27 TRUE FALSE 0 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3914780 0.4029661 U 0.4686274 0.6162291 13773 129 182000 182001 1 1 Same - - 0.000000 0 0.000000 -0.07232066 1.317406 2.858902 1.0053560 602 Organic radical activating enzymes O coenzyme PQQ synthesis protein, conjectural 1.511417 3.219537 1.0516370 - - - conserved hypothetical protein 1.054642e-03 2 3.764022e-02 -8.042404e-03 -1.097376e-01 -5.162830e-01 2.173531e+00 27 2 TRUE FALSE -1 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6838149 0.4709759 0.4034779 0.4062445 U 0.4686274 0.5573725 13773 129 182001 182002 1 173 Same - - 0.000000 0 0.000000 0.00000000 1.511417 3.219537 1.0516370 - - - conserved hypothetical protein 1.429631 3.236087 1.1069659 1695 Predicted transcriptional regulators K conserved hypothetical protein 7.508473e-04 2 6.688830e-03 -1.306211e-03 -2.481713e-03 -6.898420e-02 4.802713e-01 2 2 TRUE FALSE -2 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4618072 0.5014305 0.4966064 U 0.4686274 0.6162291 13773 129 182002 182003 1 216 Same - - 0.000000 0 0.000000 0.00000000 1.429631 3.236087 1.1069659 1695 Predicted transcriptional regulators K conserved hypothetical protein 1.473642 3.148229 1.0704629 - - - hypothetical protein 0.000000e+00 0 1.936975e-03 -4.841842e-04 1.513100e-02 -3.652649e-02 1.794690e-01 2 0 TRUE FALSE -3 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5102899 0.5852468 U 0.4686274 0.6162291 13773 129 182003 182004 1 365 Same - - 0.000000 0 0.000000 0.00000000 1.473642 3.148229 1.0704629 - - - hypothetical protein 1.425040 3.500694 1.1367223 - - - hypothetical protein 0.000000e+00 0 2.362142e-03 -5.863271e-04 1.438859e-02 -5.234688e-02 2.264094e-01 0 0 TRUE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5060667 0.5722463 U 0.4686274 0.6162291 13773 129 182004 182005 1 60 Same - - 0.000000 0 0.000000 0.00000000 1.425040 3.500694 1.1367223 - - - hypothetical protein 1.514153 3.334057 1.1582241 - - - hypothetical protein 0.000000e+00 0 7.941025e-03 -1.653877e-03 9.639221e-03 -1.012481e-01 5.761078e-01 0 0 TRUE FALSE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4906905 0.4804678 U 0.4686274 0.6162291 13773 129 182005 182006 1 147 Divergent - + 0.000000 0 0.000000 0.00000000 1.514153 3.334057 1.1582241 - - - hypothetical protein 1.383252 3.176541 1.0465540 4933 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.713510e-02 -4.276537e-03 -2.747599e-02 -3.280440e-01 1.312897e+00 0 2 TRUE FALSE -6 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4337780 0.4237791 U 0.4686274 0.6162291 13773 129 182006 182007 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.383252 3.176541 1.0465540 4933 Uncharacterized conserved protein S conserved hypothetical protein 1.397745 3.047043 1.0664146 2005 N-terminal domain of molybdenum-binding protein R conserved hypothetical protein 0.000000e+00 0 2.100493e-04 3.655632e-03 5.899788e-02 2.477505e-01 1.360813e-02 2 0 FALSE FALSE -5 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5684653 0.6412444 U 0.4686274 0.6162291 13773 129 182007 182008 1 35 Divergent - + 0.000000 0 0.000000 0.00000000 1.397745 3.047043 1.0664146 2005 N-terminal domain of molybdenum-binding protein R conserved hypothetical protein 1.414741 3.210785 1.1059589 2998 ABC-type tungstate transport system, permease component H binding protein, putative 0.000000e+00 0 2.888809e-04 1.966280e-03 3.983041e-02 1.158888e-01 3.280463e-02 0 6 TRUE FALSE -6 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5212696 0.6312229 U 0.4686274 0.6162291 13773 129 182008 182009 1 -13 Same + + 10.538476 0 14.932925 14.93292497 1.414741 3.210785 1.1059589 2998 ABC-type tungstate transport system, permease component H binding protein, putative 1.424693 3.482375 1.2069153 4662 ABC-type tungstate transport system, periplasmic component H sulfate transport system, permease protein, putative 1.078599e-01 6 9.903783e-05 9.785852e-04 3.057853e-02 4.579314e-02 7.520870e-03 H 6 6 FALSE FALSE -5 TRUE 2.6653753 1.8759625 0.5480306 2.6799517 0.7537284 1.0372045 0.5185987 0.6441287 Y 1.4497162 0.9163005 13773 129 182009 182010 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.424693 3.482375 1.2069153 4662 ABC-type tungstate transport system, periplasmic component H sulfate transport system, permease protein, putative 1.300110 2.908756 0.9731358 3839 ABC-type sugar transport systems, ATPase components G sulfate transport system, ATP-binding protein, putative 0.000000e+00 0 1.552083e-02 4.039198e-03 1.242749e-01 1.654462e-01 5.937158e-01 0 6 0 FALSE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5367822 0.4775886 N 0.5492530 0.6245624 13773 129 182010 182011 1 8 Convergent + - 0.000000 0 0.000000 0.00000000 1.300110 2.908756 0.9731358 3839 ABC-type sugar transport systems, ATPase components G sulfate transport system, ATP-binding protein, putative 1.354465 3.003846 1.0204928 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 0.000000e+00 0 2.954441e-03 1.466343e-02 1.579251e-01 7.111283e-01 3.740350e-02 0 8 FALSE FALSE -3 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7576591 0.6288792 U 0.4686274 0.6162291 13773 129 182011 182012 1 34 Same - - 0.000000 0 0.000000 0.00000000 1.354465 3.003846 1.0204928 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 1.466907 3.009005 1.0500426 - - - conserved hypothetical protein 0.000000e+00 0 1.264306e-02 -1.503715e-03 -2.009154e-02 -1.806681e-01 9.847097e-01 8 0 TRUE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4700975 0.4408238 U 0.4686274 0.6162291 13773 129 182012 182013 1 103 Divergent - + 0.000000 0 0.000000 0.00000000 1.466907 3.009005 1.0500426 - - - conserved hypothetical protein 1.482881 3.262711 1.1043710 1708 Predicted nucleotidyltransferases R paREP11 0.000000e+00 0 2.551909e-04 4.885061e-04 2.835622e-02 9.254633e-02 2.103947e-02 0 0 TRUE FALSE -5 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179098 0.6370483 U 0.4686274 0.6162291 13773 129 182013 182014 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.482881 3.262711 1.1043710 1708 Predicted nucleotidyltransferases R paREP11 1.354620 2.938037 1.0101300 1530 Ribonucleases G and E J conserved hypothetical protein 0.000000e+00 0 1.645106e-02 -3.047242e-03 6.373125e-03 -2.894660e-01 1.291877e+00 0 5 FALSE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4429392 0.4242983 U 0.4686274 0.6162291 13773 129 182014 182015 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.354620 2.938037 1.0101300 1530 Ribonucleases G and E J conserved hypothetical protein 1.364532 3.083277 1.0663114 - - - hypothetical protein 0.000000e+00 0 9.824485e-05 8.405847e-03 1.143989e-01 5.253059e-01 2.723510e-03 5 0 FALSE FALSE -3 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6862988 0.6489041 U 0.4686274 0.6162291 13773 129 182015 182016 1 14 Same + + 0.000000 0 0.000000 0.00000000 1.364532 3.083277 1.0663114 - - - hypothetical protein 1.428800 3.234002 1.0423831 1487 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 4.130468e-03 1.962424e-03 2.581882e-02 9.229071e-02 3.216622e-01 0 5 FALSE FALSE -2 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178794 0.5343942 U 0.4686274 0.6162291 13773 129 182016 182017 1 -10 Convergent + - 0.000000 0 0.000000 -0.33174076 1.428800 3.234002 1.0423831 1487 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.466663 3.209332 1.0815779 83 Homoserine kinase E homoserine kinase 6.125049e-02 5 1.433575e-03 -3.449885e-04 1.599990e-02 -3.130387e-02 1.362703e-01 5 15 FALSE FALSE -1 FALSE 0.4469764 0.2502545 0.5480306 0.4469764 0.7448207 0.8869692 0.5118079 0.5967973 U 0.4686274 0.5414575 13773 129 182017 182018 1 -43 Same - - 0.000000 0 0.000000 -0.77438996 1.466663 3.209332 1.0815779 83 Homoserine kinase E homoserine kinase 1.376838 2.990896 1.0123534 1878 Predicted metal-dependent hydrolase R conserved hypothetical protein -3.027093e-02 15 8.068472e-03 -1.138448e-03 2.095011e-02 -1.454174e-01 7.230872e-01 15 29 TRUE FALSE -2 TRUE 0.4469764 0.2193655 0.5480306 0.4469764 0.7783720 0.5246684 0.4782875 0.4626259 U 0.4686274 0.5316714 13773 129 182018 182019 1 295 Same - - 0.000000 0 0.000000 -0.31560878 1.376838 2.990896 1.0123534 1878 Predicted metal-dependent hydrolase R conserved hypothetical protein 1.494937 3.618437 1.2134142 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 3.931725e-02 3 1.394740e-02 -3.246440e-03 -2.652101e-02 -2.898936e-01 1.179299e+00 29 3 TRUE FALSE -3 TRUE 0.4469764 0.2518128 0.5480306 0.4469764 0.7136133 0.8022192 0.4427597 0.4292263 U 0.4686274 0.5419504 13773 129 182019 182020 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.494937 3.618437 1.2134142 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 1.451804 3.301686 1.1585958 - - - conserved within P. aerophilum 0.000000e+00 0 1.860460e-03 1.791175e-05 1.613235e-02 4.716667e-02 1.391181e-01 3 0 TRUE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186837 0.5960694 U 0.4686274 0.6162291 13773 129 182020 182021 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.451804 3.301686 1.1585958 - - - conserved within P. aerophilum 1.425844 3.431074 1.1845175 - - - hypothetical protein 0.000000e+00 0 6.739136e-04 -1.050924e-05 2.227199e-02 -1.638582e-02 6.969924e-02 0 0 TRUE FALSE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5165375 0.6179109 U 0.4686274 0.6162291 13773 129 182021 182022 1 72 Divergent - + 0.000000 0 0.000000 0.00000000 1.425844 3.431074 1.1845175 - - - hypothetical protein 1.334789 3.008826 1.0466275 1215 Glycosyltransferases, probably involved in cell wall biogenesis M egghead homolog 0.000000e+00 0 8.291103e-03 2.979057e-03 8.844047e-02 1.407920e-01 4.802713e-01 0 0 TRUE FALSE -6 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5280253 0.4966064 U 0.4686274 0.6162291 13773 129 182022 182023 1 150 Same + + 0.000000 0 0.000000 0.00000000 1.334789 3.008826 1.0466275 1215 Glycosyltransferases, probably involved in cell wall biogenesis M egghead homolog 1.454367 3.117971 1.0428534 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 1.429901e-02 -3.468372e-04 -1.782357e-02 -1.072388e-01 9.650084e-01 0 1 FALSE FALSE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4887314 0.4419241 U 0.4686274 0.6162291 13773 129 182023 182024 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.454367 3.117971 1.0428534 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.490593 3.203013 1.0832090 1708 Predicted nucleotidyltransferases R hypothetical protein 0.000000e+00 0 1.312328e-03 1.166016e-04 2.598098e-02 5.577954e-02 1.029115e-01 1 0 FALSE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187068 0.6052131 U 0.4686274 0.6162291 13773 129 182024 182025 1 38 Same + + 0.000000 0 0.000000 0.00000000 1.490593 3.203013 1.0832090 1708 Predicted nucleotidyltransferases R hypothetical protein 1.586574 3.316826 1.0399624 - - - hypothetical protein 0.000000e+00 0 9.212265e-03 5.299175e-03 1.252015e-01 3.747153e-01 1.556100e-01 0 0 FALSE FALSE -3 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6226910 0.5912363 U 0.4686274 0.6162291 13773 129 182025 182026 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.586574 3.316826 1.0399624 - - - hypothetical protein 1.405064 3.104771 1.0671192 - - - hypothetical protein 0.000000e+00 0 3.294583e-02 -6.262774e-03 -9.344454e-02 -3.044159e-01 1.446269e+00 0 0 FALSE FALSE -2 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4392887 0.4186719 U 0.4686274 0.6162291 13773 129 182026 182027 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.405064 3.104771 1.0671192 - - - hypothetical protein 1.436330 3.108750 1.0671967 4826 Serine protease inhibitor O serine protease inhibitor (serpin) 0.000000e+00 0 9.775817e-04 6.978255e-04 2.402233e-02 1.807035e-02 9.756633e-02 0 5 FALSE FALSE -1 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178198 0.6075710 U 0.4686274 0.6162291 13773 129 182027 182028 1 -67 Same - - 0.000000 0 0.000000 0.00000000 1.436330 3.108750 1.0671967 4826 Serine protease inhibitor O serine protease inhibitor (serpin) 1.524755 3.435518 1.1404117 - - - hypothetical protein 0.000000e+00 0 7.818835e-03 -1.105008e-03 2.090895e-02 -3.227395e-02 4.856047e-01 5 0 TRUE FALSE -2 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5114782 0.4950121 U 0.4686274 0.6162291 13773 129 182028 182029 1 172 Same - - 0.000000 0 0.000000 0.00000000 1.524755 3.435518 1.1404117 - - - hypothetical protein 1.474866 3.435088 1.0800702 - - - hypothetical protein 0.000000e+00 0 2.488873e-03 1.722027e-03 2.860386e-02 2.035741e-01 1.104300e-01 0 0 TRUE FALSE -3 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5506266 0.6027963 U 0.4686274 0.6162291 13773 129 182029 182030 1 418 Same - - 0.000000 0 0.000000 0.00000000 1.474866 3.435088 1.0800702 - - - hypothetical protein 1.357922 3.044823 1.0750385 1409 Predicted phosphohydrolases R hypothetical protein 0.000000e+00 0 1.367583e-02 -2.194045e-03 1.587212e-02 -2.306208e-01 1.097429e+00 0 0 TRUE FALSE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4569294 0.4330324 U 0.4686274 0.6162291 13773 129 182030 182031 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.357922 3.044823 1.0750385 1409 Predicted phosphohydrolases R hypothetical protein 1.349385 3.101365 1.1438373 - - - hypothetical protein 0.000000e+00 0 7.288218e-05 9.534718e-03 1.364583e-01 5.731770e-01 2.412521e-03 0 0 TRUE FALSE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7095488 0.6495169 U 0.4686274 0.6162291 13773 129 182031 182032 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.349385 3.101365 1.1438373 - - - hypothetical protein 1.410312 3.187466 1.1073070 - - - conserved hypothetical protein 0.000000e+00 0 3.712105e-03 4.190542e-03 4.759537e-02 2.436752e-01 2.213258e-01 0 0 TRUE FALSE -6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5670320 0.5739549 U 0.4686274 0.6162291 13773 129 182032 182033 1 85 Divergent - + 0.000000 0 0.000000 0.00000000 1.410312 3.187466 1.1073070 - - - conserved hypothetical protein 1.338158 3.028581 1.0791584 1840 ABC-type Fe3+ transport system, periplasmic component P extracellular solute binding protein, conjectural 0.000000e+00 0 5.206242e-03 4.651764e-03 1.034037e-01 2.630449e-01 2.836809e-01 0 1 TRUE FALSE -7 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5751306 0.5496363 U 0.4686274 0.6162291 13773 129 182033 182034 1 17 Convergent + - 2.079442 0 2.079442 2.07944154 1.338158 3.028581 1.0791584 1840 ABC-type Fe3+ transport system, periplasmic component P extracellular solute binding protein, conjectural 1.309813 3.156580 1.1122759 1178 ABC-type Fe3+ transport system, permease component P molybdenum transport system permease protein, putative 2.193686e-02 1 8.034346e-04 1.603179e-02 2.265280e-01 7.800642e-01 6.370563e-03 P 1 15 FALSE FALSE -6 FALSE 2.9335626 1.6614134 0.5480306 2.9479804 0.6329203 0.6907986 0.7781878 0.6451734 Y 1.4497162 0.8895842 13773 129 182034 182035 1 -3 Same - - 4.317488 0 6.189290 5.79559002 1.309813 3.156580 1.1122759 1178 ABC-type Fe3+ transport system, permease component P molybdenum transport system permease protein, putative 1.376224 2.989944 1.0145561 3839 ABC-type sugar transport systems, ATPase components G transporter ATP-binding protein, putative 1.633838e-02 10 4.410368e-03 1.064245e-02 1.086174e-01 5.729926e-01 9.236375e-02 0 15 10 TRUE FALSE -7 TRUE 2.8518134 1.8032037 0.5480306 2.8344026 0.7739415 0.6494466 0.7091474 0.6101085 N 0.5492530 0.8678508 13773 129 182035 182036 1 84 Divergent - + 0.000000 0 0.000000 -0.08004271 1.376224 2.989944 1.0145561 3839 ABC-type sugar transport systems, ATPase components G transporter ATP-binding protein, putative 1.322230 2.897438 0.9933358 5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) J translation initiation factor aIF-2 gamma subunit, putative 2.467265e-03 10 2.915345e-03 9.709102e-03 1.622769e-01 5.515768e-01 7.256470e-02 0 10 12 TRUE FALSE -8 FALSE 0.4469764 0.2967290 0.5480306 0.4469764 0.7739415 0.5040782 0.6996520 0.6171587 N 0.5492530 0.5648358 13773 129 182036 182037 1 149 Convergent + - 0.000000 0 0.000000 0.00000000 1.322230 2.897438 0.9933358 5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) J translation initiation factor aIF-2 gamma subunit, putative 1.299173 3.337201 1.1903911 - - - hypothetical protein 0.000000e+00 0 5.316262e-04 1.966125e-02 2.670985e-01 8.423833e-01 3.313094e-03 12 0 FALSE FALSE -7 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7927256 0.6480385 U 0.4686274 0.6162291 13773 129 182037 182038 1 22 Divergent - + 0.000000 0 0.000000 0.00000000 1.299173 3.337201 1.1903911 - - - hypothetical protein 1.520479 3.641497 1.1437996 - - - hypothetical protein 0.000000e+00 0 4.897639e-02 -1.051627e-02 -1.489437e-01 -5.923576e-01 2.472835e+00 0 0 TRUE FALSE -8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3952121 0.4035865 U 0.4686274 0.6162291 13773 129 182038 182039 1 282 Convergent + - 0.000000 0 0.000000 0.00000000 1.520479 3.641497 1.1437996 - - - hypothetical protein 1.520223 3.362322 1.1049881 2254 Predicted HD superfamily hydrolase, possibly a nuclease L conserved hypothetical protein 0.000000e+00 0 6.540419e-08 4.755190e-03 7.624713e-02 3.888247e-01 1.472486e-05 0 0 FALSE FALSE -7 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6297054 0.6556702 U 0.4686274 0.6162291 13773 129 182039 182040 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.520223 3.362322 1.1049881 2254 Predicted HD superfamily hydrolase, possibly a nuclease L conserved hypothetical protein 1.529734 3.351054 1.1063138 1203 Predicted helicases R helicase, probable 0.000000e+00 0 9.046603e-05 5.392255e-03 8.734026e-02 4.198352e-01 2.886073e-03 0 3 TRUE FALSE -8 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6437776 0.6487603 U 0.4686274 0.6162291 13773 129 182040 182041 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.529734 3.351054 1.1063138 1203 Predicted helicases R helicase, probable 1.579735 3.352593 1.0594224 - - - hypothetical protein 0.000000e+00 0 2.500033e-03 1.005449e-02 1.645415e-01 5.582253e-01 2.285828e-02 3 0 TRUE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7023937 0.6363673 U 0.4686274 0.6162291 13773 129 182041 182042 1 123 Divergent - + 0.000000 0 0.000000 0.00000000 1.579735 3.352593 1.0594224 - - - hypothetical protein 1.351635 2.812378 0.9560839 - - - hypothetical protein 0.000000e+00 0 5.202940e-02 -1.280309e-02 -1.455173e-01 -6.349813e-01 2.543327e+00 0 0 TRUE FALSE -10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3910089 0.4031382 U 0.4686274 0.6162291 13773 129 182042 182043 1 213 Same + + 0.000000 0 0.000000 0.00000000 1.351635 2.812378 0.9560839 - - - hypothetical protein 1.291084 2.787502 1.0134974 - - - hypothetical protein 0.000000e+00 0 3.666421e-03 1.599203e-02 2.477113e-01 7.375688e-01 3.681215e-02 0 0 FALSE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7644228 0.6292170 U 0.4686274 0.6162291 13773 129 182043 182044 1 1176 Convergent + - 0.000000 0 0.000000 0.00000000 1.291084 2.787502 1.0134974 - - - hypothetical protein 1.356913 3.117865 1.0828814 5551 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.333466e-03 1.514591e-02 1.552340e-01 7.103060e-01 4.851488e-02 0 1 FALSE FALSE -8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7572110 0.6244084 U 0.4686274 0.6162291 13773 129 182044 182045 1 29 Divergent - + 0.000000 0 0.000000 0.00000000 1.356913 3.117865 1.0828814 5551 Uncharacterized conserved protein S conserved hypothetical protein 1.326907 3.023658 1.0162441 - - - hypothetical protein 0.000000e+00 0 9.003584e-04 1.176135e-02 1.749400e-01 6.506880e-01 1.950985e-02 1 0 TRUE FALSE -9 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7370137 0.6378952 U 0.4686274 0.6162291 13773 129 182045 182046 1 -70 Convergent + - 0.000000 0 0.000000 0.00000000 1.326907 3.023658 1.0162441 - - - hypothetical protein 1.478232 3.447429 1.0830072 - - - paREP9, associated with SRSRs 0.000000e+00 0 2.289921e-02 -3.341100e-03 -5.585199e-02 -3.098193e-01 1.517264e+00 0 0 FALSE FALSE -8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4374168 0.4167010 U 0.4686274 0.6162291 13773 129 182046 182047 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.478232 3.447429 1.0830072 - - - paREP9, associated with SRSRs 1.346565 2.927314 1.0008937 1468 RecB family exonuclease L conserved hypothetical protein 0.000000e+00 0 1.733629e-02 -2.813508e-03 1.391853e-02 -2.827845e-01 1.334087e+00 0 0 TRUE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4445399 0.4227586 U 0.4686274 0.6162291 13773 129 182047 182048 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.346565 2.927314 1.0008937 1468 RecB family exonuclease L conserved hypothetical protein 1.404625 3.118679 1.0647742 1343 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 0.000000e+00 0 3.370938e-03 4.902635e-03 5.570879e-02 2.951062e-01 1.893552e-01 L 0 0 TRUE FALSE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5908679 0.5830153 Y 1.4497162 0.7118045 13773 129 182048 182049 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.404625 3.118679 1.0647742 1343 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 1.343412 2.969981 1.0219731 1518 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 0.000000e+00 0 3.747033e-03 5.050106e-03 1.038409e-01 3.004667e-01 2.022583e-01 L 0 6 TRUE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5921148 0.5792906 Y 1.4497162 0.7118045 13773 129 182049 182050 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.343412 2.969981 1.0219731 1518 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 1.440184 3.167706 1.0901257 4343 Uncharacterized protein conserved in archaea S conserved hypothetical protein 3.502625e-03 3 9.364995e-03 1.210301e-03 5.597312e-03 7.527348e-03 6.530823e-01 6 3 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5263810 0.5191516 0.4700463 U 0.4686274 0.6162291 13773 129 182050 182051 1 1464 Divergent - + 0.000000 0 0.000000 0.00000000 1.440184 3.167706 1.0901257 4343 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.271334 2.843642 1.0427513 - - - hypothetical protein 0.000000e+00 0 2.851060e-02 2.018182e-03 1.263501e-01 9.004546e-03 9.380584e-01 3 0 TRUE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5189422 0.4437091 U 0.4686274 0.6162291 13773 129 182051 182052 1 67 Same + + 0.000000 0 0.000000 0.00000000 1.271334 2.843642 1.0427513 - - - hypothetical protein 1.244706 2.780541 0.9847719 - - - hypothetical protein 0.000000e+00 0 7.090157e-04 3.721583e-02 4.820275e-01 9.687391e-01 1.702194e-04 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8138624 0.6547351 U 0.4686274 0.6162291 13773 129 182052 182053 1 41 Same + + 0.000000 0 0.000000 0.00000000 1.244706 2.780541 0.9847719 - - - hypothetical protein 1.480587 3.495655 1.1531062 - - - hypothetical protein 0.000000e+00 0 5.563995e-02 -6.034137e-03 -1.561368e-01 -3.657484e-01 1.849433e+00 0 0 FALSE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4245530 0.4102757 U 0.4686274 0.6162291 13773 129 182053 182054 1 6 Convergent + - 0.000000 0 0.000000 0.00000000 1.480587 3.495655 1.1531062 - - - hypothetical protein 1.372961 3.028462 1.0203953 3864 Uncharacterized protein conserved in bacteria S hypothetical protein 0.000000e+00 0 1.158355e-02 -2.289801e-03 7.422306e-03 -2.359942e-01 1.016955e+00 0 0 FALSE FALSE -10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4547333 0.4380418 U 0.4686274 0.6162291 13773 129 182054 182055 1 63 Same - - 0.000000 0 0.000000 0.00000000 1.372961 3.028462 1.0203953 3864 Uncharacterized protein conserved in bacteria S hypothetical protein 1.495283 3.566515 1.1553330 - - - hypothetical protein 0.000000e+00 0 1.496282e-02 -3.442419e-03 -3.024212e-02 -3.046827e-01 1.245202e+00 0 0 TRUE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4391029 0.4262651 U 0.4686274 0.6162291 13773 129 182055 182056 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.495283 3.566515 1.1553330 - - - hypothetical protein 1.312817 2.965511 1.0004835 714 MoxR-like ATPases R conserved hypothetical protein 0.000000e+00 0 3.329375e-02 -6.082122e-03 -6.501655e-03 -4.348952e-01 1.929605e+00 0 2 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4137159 0.4092599 U 0.4686274 0.6162291 13773 129 182056 182057 1 92 Divergent - + 0.000000 0 0.000000 0.00000000 1.312817 2.965511 1.0004835 714 MoxR-like ATPases R conserved hypothetical protein 1.376946 2.978809 1.0363653 - - - hypothetical protein 0.000000e+00 0 4.112512e-03 1.031646e-02 1.066687e-01 5.581505e-01 9.050724e-02 2 0 TRUE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7020006 0.6107212 U 0.4686274 0.6162291 13773 129 182057 182058 1 667 Same + + 0.000000 0 0.000000 0.00000000 1.376946 2.978809 1.0363653 - - - hypothetical protein 1.482439 3.371336 1.1076940 - - - paREP1 0.000000e+00 0 1.112872e-02 -2.311284e-03 -1.791342e-02 -2.347143e-01 9.908117e-01 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4552081 0.4400938 U 0.4686274 0.6162291 13773 129 182058 182059 1 43 Convergent + - 0.000000 0 0.000000 0.00000000 1.482439 3.371336 1.1076940 - - - paREP1 1.642247 3.599927 1.0243453 - - - hypothetical protein 0.000000e+00 0 2.553851e-02 5.925296e-03 1.800724e-01 3.545746e-01 2.919151e-01 0 0 FALSE FALSE -11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6144979 0.5460473 U 0.4686274 0.6162291 13773 129 182059 182060 1 -22 Same - - 0.000000 0 0.000000 0.00000000 1.642247 3.599927 1.0243453 - - - hypothetical protein 1.451408 3.276754 1.1254705 4938 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 3.641934e-02 2.945562e-06 -7.173007e-02 8.864366e-02 6.857314e-01 0 0 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177538 0.4659563 U 0.4686274 0.6162291 13773 129 182060 182061 1 324 Divergent - + 0.000000 0 0.000000 0.00000000 1.451408 3.276754 1.1254705 4938 Uncharacterized conserved protein S hypothetical protein 1.494283 3.033716 1.0015901 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 0.000000e+00 0 1.838263e-03 6.619530e-07 2.541708e-02 4.483720e-02 1.379755e-01 0 0 TRUE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185535 0.5962876 U 0.4686274 0.6162291 13773 129 182061 182062 1 -25 Same + + 0.000000 0 0.000000 0.00000000 1.494283 3.033716 1.0015901 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 1.466362 3.170812 1.0578015 1848 Predicted nucleic acid-binding protein, contains PIN domain R hypothetical protein 0.000000e+00 0 7.795845e-04 6.420419e-04 2.414203e-02 1.086854e-01 5.515108e-02 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197096 0.6221915 U 0.4686274 0.6162291 13773 129 182062 182063 1 236 Same + + 0.000000 0 0.000000 0.00000000 1.466362 3.170812 1.0578015 1848 Predicted nucleic acid-binding protein, contains PIN domain R hypothetical protein 1.433997 3.104458 1.0824354 - - - hypothetical protein 0.000000e+00 0 1.047475e-03 -2.603975e-04 1.789244e-02 -1.534802e-02 8.912722e-02 0 0 FALSE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5169628 0.6113614 U 0.4686274 0.6162291 13773 129 182063 182064 1 227 Same + + 0.000000 0 0.000000 0.00000000 1.433997 3.104458 1.0824354 - - - hypothetical protein 1.595470 3.490906 1.0550015 - - - hypothetical protein 0.000000e+00 0 2.607344e-02 -2.506278e-03 4.338098e-02 -5.678259e-02 8.580759e-01 0 0 FALSE FALSE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5048385 0.4495188 U 0.4686274 0.6162291 13773 129 182064 182065 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.595470 3.490906 1.0550015 - - - hypothetical protein 1.576129 3.533128 0.9526352 - - - hypothetical protein 0.000000e+00 0 3.740715e-04 1.797169e-02 2.176646e-01 7.031798e-01 1.847086e-03 0 0 FALSE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7531957 0.6505622 U 0.4686274 0.6162291 13773 129 182065 182066 1 105 Convergent + - 0.000000 0 0.000000 0.00000000 1.576129 3.533128 0.9526352 - - - hypothetical protein 1.360192 3.081132 1.0569825 - - - hypothetical protein 0.000000e+00 0 4.662900e-02 -1.137609e-02 -1.306648e-01 -5.896423e-01 2.367772e+00 0 0 FALSE FALSE -8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3954444 0.4042444 U 0.4686274 0.6162291 13773 129 182066 182067 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.360192 3.081132 1.0569825 - - - hypothetical protein 1.397411 3.069720 1.0825219 1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) R conserved hypothetical protein 0.000000e+00 0 1.385289e-03 4.923179e-03 6.457833e-02 3.233344e-01 7.464679e-02 0 1 TRUE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6015744 0.6164920 U 0.4686274 0.6162291 13773 129 182067 182068 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.397411 3.069720 1.0825219 1353 Predicted hydrolase of the HD superfamily (permuted catalytic motifs) R conserved hypothetical protein 1.412911 3.152547 1.0912486 - - - hypothetical protein 0.000000e+00 0 2.402316e-04 2.077330e-03 4.138695e-02 1.286458e-01 2.597465e-02 1 0 TRUE FALSE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5238475 0.6350049 U 0.4686274 0.6162291 13773 129 182068 182069 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.412911 3.152547 1.0912486 - - - hypothetical protein 1.369291 3.038229 1.0231058 - - - hypothetical protein 0.000000e+00 0 1.902666e-03 3.159455e-03 7.103628e-02 1.905456e-01 1.419954e-01 0 0 TRUE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5461636 0.5953411 U 0.4686274 0.6162291 13773 129 182069 182070 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.369291 3.038229 1.0231058 - - - hypothetical protein 1.365827 3.020195 1.0301226 1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L conserved hypothetical protein 0.000000e+00 0 1.199841e-05 7.025087e-03 1.043519e-01 4.575132e-01 6.414149e-04 0 1 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6590654 0.6527891 U 0.4686274 0.6162291 13773 129 182070 182071 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.365827 3.020195 1.0301226 1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L conserved hypothetical protein 1.454863 3.097881 1.0828116 - - - hypothetical protein 0.000000e+00 0 7.927452e-03 -2.969658e-04 -1.296881e-03 -8.938697e-02 6.705636e-01 1 0 TRUE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4953497 0.4684793 U 0.4686274 0.6162291 13773 129 182071 182072 1 85 Divergent - + 0.000000 0 0.000000 0.00000000 1.454863 3.097881 1.0828116 - - - hypothetical protein 1.352588 2.931851 1.0035076 - - - hypothetical protein 0.000000e+00 0 1.046025e-02 -3.429137e-04 4.148930e-02 -9.904235e-02 7.980262e-01 0 0 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4914915 0.4555447 U 0.4686274 0.6162291 13773 129 182072 182073 1 205 Convergent + - 0.000000 0 0.000000 0.00000000 1.352588 2.931851 1.0035076 - - - hypothetical protein 1.340636 2.972672 0.9944135 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 0.000000e+00 0 1.428544e-04 1.094331e-02 1.550506e-01 6.329334e-01 4.255485e-03 0 0 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7306089 0.6470653 U 0.4686274 0.6162291 13773 129 182073 182074 1 89 Divergent - + 0.000000 0 0.000000 0.00000000 1.340636 2.972672 0.9944135 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 1.333819 2.773058 0.9955771 - - - hypothetical protein 0.000000e+00 0 4.646986e-05 1.302211e-02 1.769486e-01 7.124476e-01 9.423910e-04 0 0 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7585562 0.6519201 U 0.4686274 0.6162291 13773 129 182074 182075 1 25 Same + + 0.000000 0 0.000000 0.00000000 1.333819 2.773058 0.9955771 - - - hypothetical protein 1.376773 3.024801 1.0337349 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 0.000000e+00 0 1.845051e-03 8.773323e-03 1.023529e-01 5.277390e-01 6.031303e-02 0 0 FALSE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6881694 0.6204913 U 0.4686274 0.6162291 13773 129 182075 182076 1 4 Convergent + - 0.000000 0 0.000000 0.00000000 1.376773 3.024801 1.0337349 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 1.367267 2.910238 0.9721223 - - - hypothetical protein 0.000000e+00 0 9.036126e-05 6.277427e-03 9.796727e-02 4.188928e-01 4.665425e-03 0 0 FALSE FALSE -12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6431479 0.6465894 U 0.4686274 0.6162291 13773 129 182076 182077 1 132 Same - - 0.000000 0 0.000000 0.00000000 1.367267 2.910238 0.9721223 - - - hypothetical protein 1.497987 3.353226 1.1364624 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 0.000000e+00 0 1.708754e-02 -3.919726e-03 -3.755202e-02 -3.377323e-01 1.385996e+00 0 0 TRUE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4306337 0.4202601 U 0.4686274 0.6162291 13773 129 182077 182078 1 104 Divergent - + 0.000000 0 0.000000 0.00000000 1.497987 3.353226 1.1364624 1517 Uncharacterized protein predicted to be involved in DNA repair L hypothetical protein 1.399525 3.133001 1.0334108 - - - hypothetical protein 0.000000e+00 0 9.694636e-03 -2.416706e-03 -6.200420e-03 -2.112252e-01 8.495661e-01 0 0 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4613246 0.4506552 U 0.4686274 0.6162291 13773 129 182078 182079 1 283 Same + + 0.000000 0 0.000000 0.00000000 1.399525 3.133001 1.0334108 - - - hypothetical protein 1.417134 3.036227 1.0025047 - - - hypothetical protein 0.000000e+00 0 3.100829e-04 1.776902e-03 3.766229e-02 1.044664e-01 3.308323e-02 0 0 FALSE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192400 0.6310514 U 0.4686274 0.6162291 13773 129 182079 182080 1 11 Same + + 0.000000 0 0.000000 0.00000000 1.417134 3.036227 1.0025047 - - - hypothetical protein 1.379378 3.110083 1.0364624 4006 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.425527e-03 2.467106e-03 5.977346e-02 1.437352e-01 1.171604e-01 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5286825 0.6014840 U 0.4686274 0.6162291 13773 129 182080 182081 1 94 Same + + 0.000000 0 0.000000 0.00000000 1.379378 3.110083 1.0364624 4006 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.348021 3.026395 1.0197298 433 Predicted ATPase R conserved hypothetical protein 0.000000e+00 0 9.832856e-04 7.444288e-03 1.217448e-01 4.640981e-01 4.136213e-02 0 0 FALSE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6614252 0.6275054 U 0.4686274 0.6162291 13773 129 182081 182082 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.348021 3.026395 1.0197298 433 Predicted ATPase R conserved hypothetical protein 1.345393 3.002090 1.0065481 5551 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 6.907119e-06 1.095744e-02 1.502525e-01 6.382108e-01 2.850733e-04 0 0 FALSE FALSE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7327336 0.6540676 U 0.4686274 0.6162291 13773 129 182082 182083 1 80 Same + + 0.000000 0 0.000000 0.00000000 1.345393 3.002090 1.0065481 5551 Uncharacterized conserved protein S conserved hypothetical protein 1.258508 2.783743 1.0040306 5551 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 7.548957e-03 2.044581e-02 3.257432e-01 7.931163e-01 3.061829e-02 0 0 FALSE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7823766 0.6326945 U 0.4686274 0.6162291 13773 129 182083 182084 1 382 Convergent + - 0.000000 0 0.000000 0.00000000 1.258508 2.783743 1.0040306 5551 Uncharacterized conserved protein S hypothetical protein 1.476612 3.751579 1.1748057 - - - hypothetical protein 0.000000e+00 0 4.756947e-02 -4.864444e-03 -1.290049e-01 -3.264443e-01 1.728327e+00 0 0 FALSE FALSE -8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4343595 0.4118192 U 0.4686274 0.6162291 13773 129 182084 182085 1 -24 Same - - 0.000000 0 0.000000 0.00000000 1.476612 3.751579 1.1748057 - - - hypothetical protein 1.381519 3.284383 1.1400881 - - - hypothetical protein 0.000000e+00 0 9.042703e-03 -1.762174e-03 1.091741e-02 -1.902558e-01 8.187264e-01 0 0 TRUE FALSE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4674923 0.4531269 U 0.4686274 0.6162291 13773 129 182085 182086 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.381519 3.284383 1.1400881 - - - hypothetical protein 1.432518 3.639107 1.1441816 - - - hypothetical protein 0.000000e+00 0 2.600865e-03 1.318868e-03 2.466428e-02 4.789349e-02 2.389957e-01 0 0 TRUE FALSE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187278 0.5668045 U 0.4686274 0.6162291 13773 129 182086 182087 1 76 Same - - 0.000000 0 0.000000 0.00000000 1.432518 3.639107 1.1441816 - - - hypothetical protein 1.497924 3.521082 1.1034645 - - - hypothetical protein 0.000000e+00 0 4.277942e-03 -8.782731e-04 1.506230e-02 -4.128085e-02 3.330787e-01 0 0 TRUE FALSE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5086893 0.5302713 U 0.4686274 0.6162291 13773 129 182087 182088 1 422 Same - - 0.000000 0 0.000000 0.00000000 1.497924 3.521082 1.1034645 - - - hypothetical protein 1.629914 3.572136 1.0607534 - - - hypothetical protein 0.000000e+00 0 1.742139e-02 8.306753e-03 1.932978e-01 4.491660e-01 1.736644e-01 0 0 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6557322 0.5866463 U 0.4686274 0.6162291 13773 129 182088 182089 1 50 Divergent - + 0.000000 0 0.000000 0.00000000 1.629914 3.572136 1.0607534 - - - hypothetical protein 1.588468 3.623836 1.1431609 - - - hypothetical protein 0.000000e+00 0 1.717724e-03 2.447088e-02 2.736412e-01 7.711963e-01 3.960398e-03 0 0 TRUE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7735652 0.6473139 U 0.4686274 0.6162291 13773 129 182089 182090 1 24 Convergent + - 0.000000 0 0.000000 0.00000000 1.588468 3.623836 1.1431609 - - - hypothetical protein 1.427006 3.242178 1.0796840 - - - hypothetical protein 0.000000e+00 0 2.607023e-02 -3.342888e-03 -6.455463e-02 -1.293997e-01 1.000000e+00 0 0 FALSE FALSE -12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4818618 0.4392459 U 0.4686274 0.6162291 13773 129 182090 182091 1 9 Divergent - + 0.000000 0 0.000000 0.00000000 1.427006 3.242178 1.0796840 - - - hypothetical protein 1.550854 3.498771 1.1209918 - - - paREP5a 0.000000e+00 0 1.533833e-02 -2.425569e-03 1.598890e-02 -1.138108e-01 8.062744e-01 0 0 TRUE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4873356 0.4545258 U 0.4686274 0.6162291 13773 129 182091 182092 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.550854 3.498771 1.1209918 - - - paREP5a 1.563780 3.421659 0.9726883 - - - paREP5b 0.000000e+00 0 1.670792e-04 1.117808e-02 1.583889e-01 5.867833e-01 1.781708e-03 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7160331 0.6506613 U 0.4686274 0.6162291 13773 129 182092 182093 1 170 Convergent + - 0.000000 0 0.000000 0.00000000 1.563780 3.421659 0.9726883 - - - paREP5b 1.450557 2.956182 0.9775689 2105 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.281938e-02 -9.395069e-05 -1.243501e-02 6.889114e-02 4.898926e-01 0 3 FALSE FALSE -11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181643 0.4941753 U 0.4686274 0.6162291 13773 129 182093 182094 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.450557 2.956182 0.9775689 2105 Uncharacterized conserved protein S conserved hypothetical protein 1.341966 3.120194 1.0612757 2512 Uncharacterized membrane-associated protein/domain S conserved protein 0.000000e+00 0 1.179200e-02 9.147640e-05 5.221420e-02 -7.197983e-02 8.284772e-01 3 0 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5007676 0.4521115 U 0.4686274 0.6162291 13773 129 182094 182095 1 35 Same - - 0.000000 0 0.000000 0.00000000 1.341966 3.120194 1.0612757 2512 Uncharacterized membrane-associated protein/domain S conserved protein 1.345662 2.893263 0.9877382 - - - hypothetical protein 0.000000e+00 0 1.366161e-05 1.156979e-02 1.539954e-01 6.623407e-01 3.115780e-04 0 0 TRUE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7400339 0.6539188 U 0.4686274 0.6162291 13773 129 182095 182096 1 435 Divergent - + 0.000000 0 0.000000 0.00000000 1.345662 2.893263 0.9877382 - - - hypothetical protein 1.484898 3.511938 1.1944881 - - - hypothetical protein 0.000000e+00 0 1.938658e-02 -3.542502e-03 -4.622059e-02 -3.280811e-01 1.470366e+00 0 0 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4335835 0.4176750 U 0.4686274 0.6162291 13773 129 182096 182097 1 128 Convergent + - 0.000000 0 0.000000 0.00000000 1.484898 3.511938 1.1944881 - - - hypothetical protein 1.359217 3.035841 1.0350597 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 1.579573e-02 -3.088355e-03 3.353756e-03 -2.964927e-01 1.288391e+00 0 5 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4413122 0.4246128 U 0.4686274 0.6162291 13773 129 182097 182098 1 -16 Same - - 2.662588 0 2.662588 2.66258783 1.359217 3.035841 1.0350597 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.449629 3.131574 1.0724042 - - - conserved hypothetical protein 3.777386e-02 1 8.174411e-03 1.625682e-04 1.069606e-03 -5.807014e-02 6.518425e-01 5 1 TRUE FALSE -14 TRUE 2.9244472 1.7076796 0.5480306 2.9399224 0.6329203 0.7874252 0.5043947 0.4702527 U 0.4686274 0.8476113 13773 129 182098 182099 1 64 Same - - 0.000000 0 0.000000 0.00000000 1.449629 3.131574 1.0724042 - - - conserved hypothetical protein 1.389557 3.065134 1.0633282 1192 ATPases involved in chromosome partitioning D hypothetical protein 0.000000e+00 0 3.608706e-03 1.090586e-04 3.171529e-02 -4.030607e-02 3.419961e-01 1 0 TRUE FALSE -15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5090252 0.5271430 U 0.4686274 0.6162291 13773 129 182099 182100 1 -9 Same - - 0.000000 0 0.000000 0.00000000 1.389557 3.065134 1.0633282 1192 ATPases involved in chromosome partitioning D hypothetical protein 1.489627 3.096056 1.0527518 - - - hypothetical protein 0.000000e+00 0 1.001412e-02 -2.364270e-03 -1.290394e-02 -2.232336e-01 8.968948e-01 0 0 TRUE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4586203 0.4466307 U 0.4686274 0.6162291 13773 129 182100 182101 1 230 Divergent - + 0.000000 0 0.000000 0.00000000 1.489627 3.096056 1.0527518 - - - hypothetical protein 1.302487 2.792072 1.1098149 - - - hypothetical protein 0.000000e+00 0 3.502145e-02 -5.693325e-03 6.765660e-03 -4.162730e-01 1.914708e+00 0 0 TRUE FALSE -17 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4163181 0.4094465 U 0.4686274 0.6162291 13773 129 182101 182102 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.302487 2.792072 1.1098149 - - - hypothetical protein 1.342541 3.064550 1.0435308 - - - hypothetical protein 0.000000e+00 0 1.604327e-03 1.620865e-02 1.840353e-01 7.718395e-01 1.489037e-02 0 0 FALSE FALSE -16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7744870 0.6404563 U 0.4686274 0.6162291 13773 129 182102 182103 1 16 Same - - 0.000000 0 0.000000 0.00000000 1.342541 3.064550 1.0435308 - - - hypothetical protein 1.428632 3.320675 1.1023683 - - - hypothetical protein 0.000000e+00 0 7.411562e-03 2.477606e-03 2.093234e-02 1.100831e-01 4.696930e-01 0 0 TRUE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199426 0.4991754 U 0.4686274 0.6162291 13773 129 182103 182104 1 426 Divergent - + 0.000000 0 0.000000 0.00000000 1.428632 3.320675 1.1023683 - - - hypothetical protein 1.322051 2.914105 1.0054700 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 0.000000e+00 0 1.135941e-02 2.943986e-03 9.632816e-02 1.195659e-01 5.714571e-01 0 3 TRUE FALSE -18 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5220337 0.4812875 U 0.4686274 0.6162291 13773 129 182104 182105 1 29 Same + + 0.000000 0 0.000000 -0.28357905 1.322051 2.914105 1.0054700 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 1.319153 2.837282 0.9486403 731 Fe-S oxidoreductases C conserved hypothetical protein 7.846874e-02 3 8.399987e-06 1.710417e-02 2.226498e-01 8.014329e-01 9.954005e-05 3 12 FALSE FALSE -17 TRUE 0.4469764 0.2567499 0.5480306 0.4469764 0.7136133 0.9433797 0.7861221 0.6550803 U 0.4686274 0.5435116 13773 129 182105 182106 1 157 Same + + 0.000000 0 0.000000 0.00000000 1.319153 2.837282 0.9486403 731 Fe-S oxidoreductases C conserved hypothetical protein 1.253134 2.620533 1.1401827 - - - hypothetical protein 0.000000e+00 0 4.358472e-03 2.621776e-02 3.826929e-01 8.877942e-01 7.388346e-03 12 0 FALSE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8032236 0.6442479 U 0.4686274 0.6162291 13773 129 182106 182107 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.253134 2.620533 1.1401827 - - - hypothetical protein 1.525278 3.592011 1.1721957 2445 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 7.406215e-02 -1.464831e-02 -2.364908e-01 -6.410586e-01 2.677229e+00 0 0 FALSE FALSE -15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3905393 0.4024852 U 0.4686274 0.6162291 13773 129 182107 182108 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.525278 3.592011 1.1721957 2445 Uncharacterized conserved protein S conserved hypothetical protein 1.371823 3.081781 1.0769192 1708 Predicted nucleotidyltransferases R paREP11 0.000000e+00 0 2.354845e-02 -5.879032e-03 -4.578598e-02 -4.195566e-01 1.678248e+00 0 0 FALSE FALSE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4154541 0.4125702 U 0.4686274 0.6162291 13773 129 182108 182109 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.371823 3.081781 1.0769192 1708 Predicted nucleotidyltransferases R paREP11 1.364070 2.895042 1.0274558 1708 Predicted nucleotidyltransferases R hypothetical protein 0.000000e+00 0 6.010976e-05 6.948335e-03 1.052655e-01 4.527447e-01 3.138751e-03 0 0 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6577268 0.6484515 U 0.4686274 0.6162291 13773 129 182109 182110 1 -30 Same - - 0.000000 0 0.000000 0.00000000 1.364070 2.895042 1.0274558 1708 Predicted nucleotidyltransferases R hypothetical protein 1.346838 3.013928 1.0334238 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 2.969339e-04 9.130092e-03 1.358859e-01 5.609512e-01 9.650084e-03 0 0 TRUE FALSE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7035757 0.6430012 U 0.4686274 0.6162291 13773 129 182110 182111 1 59 Divergent - + 0.000000 0 0.000000 0.00000000 1.346838 3.013928 1.0334238 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.326828 2.963686 0.9782251 819 Putative transcription activator K conserved protein (tenA homolog) 0.000000e+00 0 4.004108e-04 1.302394e-02 1.846602e-01 7.039508e-01 6.493663e-03 0 24 TRUE FALSE -15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7540854 0.6450314 U 0.4686274 0.6162291 13773 129 182111 182112 1 -13 Same + + 0.000000 0 0.000000 -0.13150953 1.326828 2.963686 0.9782251 819 Putative transcription activator K conserved protein (tenA homolog) 1.334649 2.930500 1.0065902 - - - conserved hypothetical protein 3.122295e-02 2 6.116821e-05 1.454229e-02 1.859775e-01 7.552946e-01 4.953443e-04 24 2 FALSE FALSE -14 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.7411783 0.7680630 0.6533218 U 0.4686274 0.5537552 13773 129 182112 182113 1 56 Same + + 0.000000 0 0.000000 -0.13150953 1.334649 2.930500 1.0065902 - - - conserved hypothetical protein 1.356582 3.073122 1.0594863 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 7.877708e-02 2 4.810961e-04 1.106858e-02 1.383707e-01 6.367654e-01 1.342966e-02 2 5 FALSE FALSE -13 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.9476794 0.7318825 0.6413060 U 0.4686274 0.5537552 13773 129 182113 182114 1 15 Convergent + - 0.000000 0 0.000000 0.00000000 1.356582 3.073122 1.0594863 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.299047 2.771566 1.0215941 - - - ribosomal protein L24, conjectural 0.000000e+00 0 3.310344e-03 1.444399e-02 2.257334e-01 7.034036e-01 4.230393e-02 5 0 FALSE FALSE -12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7536403 0.6271652 U 0.4686274 0.6162291 13773 129 182114 182115 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.299047 2.771566 1.0215941 - - - ribosomal protein L24, conjectural 1.408423 3.030923 1.0419023 1635 Flavoprotein involved in thiazole biosynthesis H thiamine biosynthetic enzyme (thi1) 0.000000e+00 0 1.196324e-02 6.546215e-03 4.302651e-02 3.113307e-01 3.835820e-01 0 12 TRUE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5969203 0.5159995 U 0.4686274 0.6162291 13773 129 182115 182116 1 87 Divergent - + 0.000000 0 0.000000 -0.13150953 1.408423 3.030923 1.0419023 1635 Flavoprotein involved in thiazole biosynthesis H thiamine biosynthetic enzyme (thi1) 1.303872 3.110714 1.0452293 477 Permeases of the major facilitator superfamily GEPR metabolite transport protein 2.741822e-02 3 1.093092e-02 6.338864e-03 1.454301e-01 3.072972e-01 3.685226e-01 12 3 TRUE FALSE -14 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7136133 0.7221790 0.5946306 0.5189918 U 0.4686274 0.5537552 13773 129 182116 182117 1 92 Same + + 0.000000 0 0.000000 0.00000000 1.303872 3.110714 1.0452293 477 Permeases of the major facilitator superfamily GEPR metabolite transport protein 1.347262 3.069932 1.0038248 - - - P. aerophilum family 562 protein 0.000000e+00 0 1.882616e-03 1.536150e-02 1.726199e-01 7.459856e-01 1.908342e-02 3 0 FALSE FALSE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7662401 0.6380977 U 0.4686274 0.6162291 13773 129 182117 182118 1 121 Same + + 0.000000 0 0.000000 0.00000000 1.347262 3.069932 1.0038248 - - - P. aerophilum family 562 protein 1.332650 2.858858 0.9511731 - - - P. aerophilum family 577 protein 0.000000e+00 0 2.134954e-04 1.236485e-02 1.735809e-01 6.878489e-01 4.255485e-03 0 0 FALSE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7492107 0.6470653 U 0.4686274 0.6162291 13773 129 182118 182119 1 42 Convergent + - 0.000000 0 0.000000 0.00000000 1.332650 2.858858 0.9511731 - - - P. aerophilum family 577 protein 1.302669 3.067022 0.9890386 5551 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 8.988353e-04 1.765983e-02 2.475852e-01 8.109864e-01 6.008332e-03 0 0 FALSE FALSE -11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7889446 0.6454790 U 0.4686274 0.6162291 13773 129 182119 182120 1 5876 Same - - 0.000000 0 0.000000 0.00000000 1.302669 3.067022 0.9890386 5551 Uncharacterized conserved protein S conserved hypothetical protein 1.315799 2.785245 0.8751263 1468 RecB family exonuclease L conserved hypothetical protein 0.000000e+00 0 1.723899e-04 2.016595e-02 2.470436e-01 8.506699e-01 1.246312e-03 0 1 TRUE FALSE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7946235 0.6515199 U 0.4686274 0.6162291 13773 129 182120 182121 1 -16 Same - - 2.197225 0 2.197225 2.19722458 1.315799 2.785245 0.8751263 1468 RecB family exonuclease L conserved hypothetical protein 1.449659 3.062475 1.0453462 1343 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 4.578021e-02 1 1.791838e-02 2.351307e-04 -2.319595e-02 -7.291456e-02 9.710492e-01 L 1 3 TRUE FALSE -13 TRUE 2.9321590 1.6745314 0.5480306 2.9469979 0.6329203 0.8313457 0.5005150 0.4416178 Y 1.4497162 0.8912321 13773 129 182121 182122 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.449659 3.062475 1.0453462 1343 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 1.305472 2.923756 1.0007464 1518 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 5.631536e-04 1 2.078969e-02 2.530381e-04 7.776180e-02 -7.501727e-02 1.023156e+00 L 3 1 TRUE FALSE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.4997441 0.4376225 Y 1.4497162 0.7118045 13773 129 182122 182123 1 -19 Same - - 2.856470 0 2.856470 2.85647021 1.305472 2.923756 1.0007464 1518 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 1.397765 3.022693 1.0203698 4343 Uncharacterized protein conserved in archaea S conserved hypothetical protein 5.285113e-02 1 8.517898e-03 7.825407e-03 6.546491e-02 4.108089e-01 2.397466e-01 1 2 TRUE FALSE -15 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6329203 0.8555544 0.6390953 0.5661218 U 0.4686274 0.8518227 13773 129 182123 182124 1 79 Divergent - + 0.000000 0 0.000000 0.00000000 1.397765 3.022693 1.0203698 4343 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.619439 3.720184 1.1963161 640 Predicted transcriptional regulators K conserved hypothetical protein 3.728161e-04 1 4.913950e-02 -9.011979e-03 -2.022172e-02 -3.942140e-01 1.781190e+00 2 1 TRUE FALSE -16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.4205852 0.4110414 U 0.4686274 0.6162291 13773 129 182124 182125 1 570 Convergent + - 0.000000 0 0.000000 0.00000000 1.619439 3.720184 1.1963161 640 Predicted transcriptional regulators K conserved hypothetical protein 1.632783 3.676946 1.1125379 - - - hypothetical protein 0.000000e+00 0 1.780461e-04 3.048189e-02 3.889814e-01 8.179083e-01 4.953443e-04 1 0 FALSE FALSE -15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7894161 0.6533218 U 0.4686274 0.6162291 13773 129 182125 182126 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.632783 3.676946 1.1125379 - - - hypothetical protein 1.476107 3.301347 1.1032503 - - - conserved hypothetical protein 0.000000e+00 0 2.454724e-02 4.482902e-03 -8.851408e-03 3.014456e-01 3.437937e-01 0 0 TRUE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5923650 0.5261944 U 0.4686274 0.6162291 13773 129 182126 182127 1 -6 Same - - 0.000000 0 0.000000 0.00000000 1.476107 3.301347 1.1032503 - - - conserved hypothetical protein 1.506704 3.223569 1.0976056 2254 Predicted HD superfamily hydrolase, possibly a nuclease L conserved hypothetical protein 0.000000e+00 0 9.361976e-04 1.366980e-03 4.293898e-02 1.804125e-01 4.784107e-02 0 1 TRUE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5422309 0.6247981 U 0.4686274 0.6162291 13773 129 182127 182128 1 83 Same - - 2.079442 0 2.079442 2.07944154 1.506704 3.223569 1.0976056 2254 Predicted HD superfamily hydrolase, possibly a nuclease L conserved hypothetical protein 1.553015 3.398913 1.1434635 1203 Predicted helicases R helicase, probable 7.158483e-02 1 2.144637e-03 5.620856e-03 1.049145e-01 4.138133e-01 4.293769e-02 1 1 TRUE FALSE -18 TRUE 2.9335626 1.6614134 0.5480306 2.9479804 0.6329203 0.9205230 0.6412688 0.6268270 U 0.4686274 0.8396881 13773 129 182128 182129 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.553015 3.398913 1.1434635 1203 Predicted helicases R helicase, probable 1.509604 3.324866 1.1235690 1688 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L hypothetical protein 0.000000e+00 0 1.884446e-03 5.915561e-03 7.228396e-02 4.248252e-01 3.710724e-02 1 0 TRUE FALSE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6459945 0.6290639 U 0.4686274 0.6162291 13773 129 182129 182130 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.509604 3.324866 1.1235690 1688 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) L hypothetical protein 1.462549 3.136345 1.0732647 1857 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 0.000000e+00 0 2.214190e-03 6.494300e-04 2.004174e-02 1.148410e-01 1.284532e-01 L 0 5 TRUE FALSE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5210348 0.5984864 Y 1.4497162 0.7118045 13773 129 182130 182131 1 4 Same - - 0.000000 0 0.000000 0.00000000 1.462549 3.136345 1.0732647 1857 Uncharacterized protein predicted to be involved in DNA repair L conserved hypothetical protein 1.558314 3.351615 1.0897868 - - - conserved hypothetical protein 0.000000e+00 0 9.170905e-03 1.192853e-03 6.340083e-02 1.569859e-01 3.190559e-01 5 0 TRUE FALSE -21 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5333489 0.5354147 U 0.4686274 0.6162291 13773 129 182131 182132 1 410 Divergent - + 0.000000 0 0.000000 0.00000000 1.558314 3.351615 1.0897868 - - - conserved hypothetical protein 1.480920 3.383929 1.1112134 5551 Uncharacterized conserved protein S conserved within P. aerophilum 0.000000e+00 0 5.989849e-03 3.157074e-03 3.083312e-02 2.868238e-01 1.568233e-01 0 0 TRUE FALSE -22 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5876594 0.5907175 U 0.4686274 0.6162291 13773 129 182132 182133 1 167 Convergent + - 0.000000 0 0.000000 0.00000000 1.480920 3.383929 1.1112134 5551 Uncharacterized conserved protein S conserved within P. aerophilum 1.378884 3.002907 1.0619950 1672 Predicted ATPase (AAA+ superfamily) R hypothetical protein 0.000000e+00 0 1.041134e-02 -2.140977e-03 6.842275e-03 -2.204135e-01 9.291599e-01 0 0 FALSE FALSE -21 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4592279 0.4450104 U 0.4686274 0.6162291 13773 129 182133 182134 1 73 Same - - 0.000000 0 0.000000 0.00000000 1.378884 3.002907 1.0619950 1672 Predicted ATPase (AAA+ superfamily) R hypothetical protein 1.328012 3.170488 1.0572086 - - - hypothetical protein 0.000000e+00 0 2.587978e-03 8.946220e-03 1.506465e-01 5.165658e-01 8.019807e-02 0 0 TRUE FALSE -22 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6814941 0.6143382 U 0.4686274 0.6162291 13773 129 182134 182135 1 138 Same - - 0.000000 0 0.000000 0.00000000 1.328012 3.170488 1.0572086 - - - hypothetical protein 1.353986 2.877765 1.0122579 152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase F phosphoribosylaminoimidazole-succinocarboxamide synthase (purC) 0.000000e+00 0 6.746476e-04 1.201819e-02 1.466942e-01 6.594599e-01 1.433377e-02 0 47 TRUE FALSE -23 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7387371 0.6407068 U 0.4686274 0.6162291 13773 129 182135 182136 1 115 Divergent - + 4.969813 0 4.969813 -3.31949997 1.353986 2.877765 1.0122579 152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase F phosphoribosylaminoimidazole-succinocarboxamide synthase (purC) 1.312507 2.772512 0.9705074 151 Phosphoribosylamine-glycine ligase F phosphoribosylglycinamide synthetase (GARS) (purD) 8.766562e-02 47 1.720458e-03 1.352843e-02 2.038057e-01 6.901459e-01 2.572786e-02 F 47 60 TRUE FALSE -24 FALSE 2.8267047 0.1886879 0.5480306 2.8904122 0.7720302 0.9730339 0.7500936 0.6351292 Y 1.4497162 0.5555994 13773 129 182136 182137 1 3 Same + + 2.856470 0 5.519058 5.51905803 1.312507 2.772512 0.9705074 151 Phosphoribosylamine-glycine ligase F phosphoribosylglycinamide synthetase (GARS) (purD) 1.356936 2.951262 1.0114079 34 Glutamine phosphoribosylpyrophosphate amidotransferase F amidophosphoribosyltransferase (purF) 5.755097e-03 2 1.973930e-03 1.311864e-02 1.477971e-01 6.761043e-01 3.088746e-02 F 60 2 FALSE FALSE -23 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 0.5508290 0.7452567 0.6324772 Y 1.4497162 0.9052318 13773 129 182137 182138 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.356936 2.951262 1.0114079 34 Glutamine phosphoribosylpyrophosphate amidotransferase F amidophosphoribosyltransferase (purF) 1.365619 2.886099 0.9803308 299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN F phosphoribosylglycinamide formyltransferase 6.217154e-03 2 7.539466e-05 8.101872e-03 1.114929e-01 5.110487e-01 2.264094e-03 F 2 15 FALSE FALSE -22 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5596796 0.6778572 0.6496996 Y 1.4497162 0.7118045 13773 129 182138 182139 1 -15 Same + + 2.512306 0 2.512306 -0.08251681 1.365619 2.886099 0.9803308 299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN F phosphoribosylglycinamide formyltransferase 1.340335 2.977437 1.0280686 190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase H methylenetetrahydrofolate dehydrogenase (folD) 2.000415e-04 15 6.392917e-04 9.525816e-03 1.447546e-01 5.747307e-01 1.950985e-02 0 15 58 FALSE FALSE -21 TRUE 2.9301853 0.2963655 0.5480306 2.9452541 0.7783720 0.4439192 0.7103530 0.6378952 N 0.5492530 0.4881223 13773 129 182139 182140 1 -10 Same + + 0.000000 0 0.000000 -9.68383689 1.340335 2.977437 1.0280686 190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase H methylenetetrahydrofolate dehydrogenase (folD) 1.375830 2.975203 0.9883567 150 Phosphoribosylaminoimidazole (AIR) synthetase F phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM) 3.597802e-03 50 1.259898e-03 8.391825e-03 1.020353e-01 5.179593e-01 4.325634e-02 0 58 50 FALSE FALSE -20 TRUE 0.4469764 0.1777640 0.5480306 0.4469764 0.7714403 0.5307060 0.6833319 0.6266433 N 0.5492530 0.5272819 13773 129 182140 182141 1 -3 Convergent + - 6.684612 0 20.733018 17.45284170 1.375830 2.975203 0.9883567 150 Phosphoribosylaminoimidazole (AIR) synthetase F phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (purM) 1.324389 2.818677 0.9765146 47 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain F phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ) 3.130325e-02 44 2.646207e-03 9.596767e-03 1.594082e-01 5.514378e-01 6.848886e-02 F 50 44 FALSE FALSE -19 FALSE 2.7675554 1.8924311 0.5480306 2.5787748 0.7723149 0.7424686 0.6992622 0.6183298 Y 1.4497162 0.9169360 13773 129 182141 182142 1 -3 Same - - 10.007811 0 12.205035 12.20503511 1.324389 2.818677 0.9765146 47 Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain F phosphoribosylformylglycinamidine synthase I (FGAM synthase I) (purQ) 1.325444 2.949341 1.0550618 1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component F conserved hypothetical protein 1.163708e-02 6 1.112408e-06 1.599607e-02 2.070907e-01 7.802980e-01 9.423910e-06 F 44 6 TRUE FALSE -20 TRUE 2.6790207 1.8677692 0.5480306 2.7025421 0.7537284 0.6099148 0.7786519 0.6557762 Y 1.4497162 0.9153654 13773 129 182142 182143 1 145 Divergent - + 5.649678 0 8.312266 8.10992562 1.325444 2.949341 1.0550618 1828 Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component F conserved hypothetical protein 1.353628 2.974288 1.0474049 46 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain F phosphoribosylformylglycinamidine synthase II (FGAM synthase II) (purL) 1.283666e-02 6 7.943656e-04 1.231341e-02 1.486972e-01 6.659265e-01 1.603537e-02 F 6 43 TRUE FALSE -21 FALSE 2.7882442 1.8191823 0.5480306 2.7997445 0.7537284 0.6216452 0.7422032 0.6397376 Y 1.4497162 0.9093343 13773 129 182143 182144 1 3 Same + + 30.029553 0 55.127062 52.60789189 1.353628 2.974288 1.0474049 46 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain F phosphoribosylformylglycinamidine synthase II (FGAM synthase II) (purL) 1.353555 2.925816 0.9949158 34 Glutamine phosphoribosylpyrophosphate amidotransferase F amidophosphoribosyltransferase (purF) 1.798730e-01 43 5.344589e-09 9.565104e-03 1.326119e-01 5.708769e-01 5.889944e-07 F 43 61 FALSE FALSE -20 TRUE 2.1535475 2.0412523 0.5480306 2.1827676 0.7726613 1.1178543 0.7083459 0.6559820 Y 1.4497162 0.9350612 13773 129 182144 182145 1 39 Same + + 0.000000 0 0.000000 0.00000000 1.353555 2.925816 0.9949158 34 Glutamine phosphoribosylpyrophosphate amidotransferase F amidophosphoribosyltransferase (purF) 1.348020 3.038279 0.9862461 - - - conserved within P. aerophilum, authentic frameshift 0.000000e+00 0 3.063419e-05 1.011377e-02 1.418189e-01 5.981444e-01 1.246312e-03 61 0 FALSE FALSE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7197306 0.6515199 U 0.4686274 0.6162291 13773 129 182145 182146 1 234 Convergent + - 0.000000 0 0.000000 0.00000000 1.348020 3.038279 0.9862461 - - - conserved within P. aerophilum, authentic frameshift 1.408992 3.076923 1.1179264 - - - hypothetical protein 0.000000e+00 0 3.717519e-03 4.383134e-03 4.941523e-02 2.550464e-01 2.198840e-01 0 0 FALSE FALSE -18 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5720545 0.5744992 U 0.4686274 0.6162291 13773 129 182146 182147 1 135 Divergent - + 0.000000 0 0.000000 0.00000000 1.408992 3.076923 1.1179264 - - - hypothetical protein 1.257211 2.752588 0.9087780 - - - paREP8 0.000000e+00 0 2.303730e-02 8.233550e-03 2.081970e-01 3.173855e-01 4.386648e-01 0 1 TRUE FALSE -19 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5984605 0.5058537 U 0.4686274 0.6162291 13773 129 182147 182148 1 187 Convergent + - 0.000000 0 0.000000 -0.05918887 1.257211 2.752588 0.9087780 - - - paREP8 1.333547 2.875773 0.9267348 26 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) F phosphoribosylaminoimidazole carboxylase ATPase subunit (AIRC) (purK) 5.899547e-03 1 5.827209e-03 2.288345e-02 2.278089e-01 8.471171e-01 1.545757e-02 1 48 FALSE FALSE -18 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.5540132 0.7941485 0.6400987 U 0.4686274 0.5589164 13773 129 182148 182149 1 208 Divergent - + 0.000000 0 0.000000 0.00000000 1.333547 2.875773 0.9267348 26 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) F phosphoribosylaminoimidazole carboxylase ATPase subunit (AIRC) (purK) 1.527679 3.967124 1.1534253 - - - hypothetical protein 0.000000e+00 0 3.768705e-02 -8.989962e-03 -1.048643e-01 -5.717875e-01 2.325449e+00 48 0 TRUE FALSE -19 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3963719 0.4049762 U 0.4686274 0.6162291 13773 129 182149 182150 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.527679 3.967124 1.1534253 - - - hypothetical protein 1.588008 3.921728 1.1739482 - - - hypothetical protein 0.000000e+00 0 3.639629e-03 1.042183e-02 1.752106e-01 5.615861e-01 3.252722e-02 0 0 FALSE FALSE -18 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7039707 0.6313366 U 0.4686274 0.6162291 13773 129 182150 182151 1 585 Divergent - + 0.000000 0 0.000000 0.00000000 1.588008 3.921728 1.1739482 - - - hypothetical protein 1.336773 2.842086 0.9797082 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 6.311887e-02 -1.565876e-02 -1.763826e-01 -7.165735e-01 2.866304e+00 0 0 TRUE FALSE -19 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3858170 0.4013896 U 0.4686274 0.6162291 13773 129 182151 182152 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.336773 2.842086 0.9797082 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.299540 2.674963 1.0068584 - - - conserved within P. aerophilum 0.000000e+00 0 1.386298e-03 1.740523e-02 2.494404e-01 8.024843e-01 9.650084e-03 0 0 FALSE FALSE -18 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7870616 0.6430012 U 0.4686274 0.6162291 13773 129 182152 182153 1 295 Same + + 0.000000 0 0.000000 0.00000000 1.299540 2.674963 1.0068584 - - - conserved within P. aerophilum 1.466266 3.184901 1.1025990 1002 Type II restriction enzyme, methylase subunits V hypothetical protein 0.000000e+00 0 2.779744e-02 -2.258535e-03 -6.366689e-02 -2.193215e-01 1.387803e+00 0 0 FALSE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4595303 0.4201650 U 0.4686274 0.6162291 13773 129 182153 182154 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.466266 3.184901 1.1025990 1002 Type II restriction enzyme, methylase subunits V hypothetical protein 1.275699 2.796367 0.9475117 4930 Predicted ATP-dependent Lon-type protease O hypothetical protein 0.000000e+00 0 3.631585e-02 -2.613135e-03 6.801289e-02 -2.257250e-01 1.453662e+00 0 0 0 FALSE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4581621 0.4182159 N 0.5492530 0.6245624 13773 129 182154 182155 1 442 Convergent + - 0.000000 0 0.000000 0.00000000 1.275699 2.796367 0.9475117 4930 Predicted ATP-dependent Lon-type protease O hypothetical protein 1.410884 3.160823 1.0789136 433 Predicted ATPase R conserved hypothetical protein 0.000000e+00 0 1.827509e-02 7.117106e-03 2.972959e-02 2.989736e-01 4.447856e-01 0 2 FALSE FALSE -15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5916151 0.5049034 U 0.4686274 0.6162291 13773 129 182155 182156 1 -10 Same - - 2.662588 0 2.662588 2.66258783 1.410884 3.160823 1.0789136 433 Predicted ATPase R conserved hypothetical protein 1.413087 3.094821 1.0538033 - - - conserved hypothetical protein 5.285113e-02 1 4.852330e-06 1.551710e-03 3.843983e-02 8.740677e-02 4.953443e-04 2 1 TRUE FALSE -16 TRUE 2.9244472 1.7076796 0.5480306 2.9399224 0.6329203 0.8555544 0.5177076 0.6533218 U 0.4686274 0.8476113 13773 129 182156 182157 1 332 Same - - 0.000000 0 0.000000 0.00000000 1.413087 3.094821 1.0538033 - - - conserved hypothetical protein 1.617235 3.619928 1.1417956 - - - hypothetical protein 0.000000e+00 0 4.167646e-02 -6.352716e-03 1.257954e-02 -2.539167e-01 1.384189e+00 1 0 TRUE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4513429 0.4204509 U 0.4686274 0.6162291 13773 129 182157 182158 1 234 Same - - 0.000000 0 0.000000 0.00000000 1.617235 3.619928 1.1417956 - - - hypothetical protein 1.379935 3.032847 1.0164195 - - - hypothetical protein 0.000000e+00 0 5.631132e-02 -1.185071e-02 -1.747028e-01 -5.201527e-01 2.175795e+00 0 0 TRUE FALSE -18 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4027970 0.4061026 U 0.4686274 0.6162291 13773 129 182158 182159 1 340 Same - - 0.000000 0 0.000000 0.00000000 1.379935 3.032847 1.0164195 - - - hypothetical protein 1.288153 2.853800 0.9544612 41 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase F phosphoribosylaminoimidazole carboxylase catalytic subunit (AIRC) (purE) 0.000000e+00 0 8.423926e-03 1.166472e-02 2.118284e-01 5.644687e-01 1.478382e-01 0 36 TRUE FALSE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7043661 0.5936859 U 0.4686274 0.6162291 13773 129 182159 182160 1 72 Same - - 0.000000 0 0.000000 -1.45083288 1.288153 2.853800 0.9544612 41 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase F phosphoribosylaminoimidazole carboxylase catalytic subunit (AIRC) (purE) 1.272919 2.702613 0.9679901 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein) -1.906483e-02 8 2.320949e-04 2.913407e-02 3.746018e-01 9.447423e-01 7.126832e-05 36 8 TRUE FALSE -20 TRUE 0.4469764 0.2027982 0.5480306 0.4469764 0.7652913 0.5247025 0.8104626 0.6552829 U 0.4686274 0.5264121 13773 129 182160 182161 1 94 Divergent - + 0.000000 0 0.000000 0.00000000 1.272919 2.702613 0.9679901 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein) 1.631059 3.686788 1.1453645 - - - P. aerophilum family 562 protein, associated with P. aerophilum family 577, degenerate 0.000000e+00 0 1.282646e-01 -3.206579e-02 -3.531005e-01 -8.922983e-01 3.573057e+00 8 0 TRUE FALSE -21 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3793751 0.3994070 U 0.4686274 0.6162291 13773 129 182161 182162 1 -9 Same + + 0.000000 0 0.000000 0.00000000 1.631059 3.686788 1.1453645 - - - P. aerophilum family 562 protein, associated with P. aerophilum family 577, degenerate 1.353443 2.967067 1.0157882 - - - P. aerophilum family 577 protein, associated with P. aerophilum family 562, degenerate 0.000000e+00 0 7.707050e-02 -1.759823e-02 -2.426365e-01 -6.923729e-01 2.794003e+00 0 0 FALSE FALSE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3884200 0.4018685 U 0.4686274 0.6162291 13773 129 182162 182163 1 266 Convergent + - 0.000000 0 0.000000 0.00000000 1.353443 2.967067 1.0157882 - - - P. aerophilum family 577 protein, associated with P. aerophilum family 562, degenerate 1.559880 3.599496 1.0954440 - - - hypothetical protein 0.000000e+00 0 4.261615e-02 -1.062628e-02 -9.798341e-02 -5.894762e-01 2.358334e+00 0 0 FALSE FALSE -19 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3956764 0.4043486 U 0.4686274 0.6162291 13773 129 182163 182164 1 53 Same - - 0.000000 0 0.000000 0.00000000 1.559880 3.599496 1.0954440 - - - hypothetical protein 1.414217 3.110190 1.0697727 1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) R tryptophan synthase beta subunit (trpB), authentic frameshift 0.000000e+00 0 2.121772e-02 -4.033101e-03 -5.279743e-02 -2.090341e-01 1.095822e+00 0 13 TRUE FALSE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4620625 0.4332060 U 0.4686274 0.6162291 13773 129 182164 182165 1 240 Divergent - + 0.000000 0 0.000000 -0.63586757 1.414217 3.110190 1.0697727 1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) R tryptophan synthase beta subunit (trpB), authentic frameshift 1.372650 3.074493 1.0230932 2263 Predicted RNA methylase J methylase, conjectural 3.831673e-02 11 1.727815e-03 2.927329e-03 6.720118e-02 1.721336e-01 1.385462e-01 13 11 TRUE FALSE -21 FALSE 0.4469764 0.2282500 0.5480306 0.4469764 0.7764261 0.7937239 0.5386112 0.5961785 U 0.4686274 0.5344890 13773 129 182165 182166 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.372650 3.074493 1.0230932 2263 Predicted RNA methylase J methylase, conjectural 1.338412 2.967970 1.0435991 330 Membrane protease subunits, stomatin/prohibitin homologs O prohibitin homolog (hflK family) 0.000000e+00 0 1.172274e-03 8.896465e-03 1.414279e-01 5.385323e-01 3.981602e-02 0 11 0 FALSE FALSE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6915680 0.6280980 N 0.5492530 0.6245624 13773 129 182166 182167 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.338412 2.967970 1.0435991 330 Membrane protease subunits, stomatin/prohibitin homologs O prohibitin homolog (hflK family) 1.391668 3.294362 1.1335269 - - - hypothetical protein 0.000000e+00 0 2.836294e-03 6.747744e-03 7.627639e-02 4.101875e-01 1.240899e-01 0 0 FALSE FALSE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6384779 0.5996887 U 0.4686274 0.6162291 13773 129 182167 182168 1 41 Same + + 0.000000 0 0.000000 0.00000000 1.391668 3.294362 1.1335269 - - - hypothetical protein 1.324458 2.916216 0.9997461 681 Signal peptidase I U signal peptidase 0.000000e+00 0 4.517209e-03 7.581098e-03 1.412371e-01 4.311651e-01 1.562160e-01 0 3 FALSE FALSE -18 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6475907 0.5909581 U 0.4686274 0.6162291 13773 129 182168 182169 1 554 Same + + 0.000000 0 0.000000 0.00000000 1.324458 2.916216 0.9997461 681 Signal peptidase I U signal peptidase 1.501985 3.148664 1.0485193 - - - hypothetical protein 0.000000e+00 0 3.151562e-02 -6.421847e-03 -8.876598e-02 -4.576045e-01 1.963870e+00 3 0 FALSE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4108634 0.4085563 U 0.4686274 0.6162291 13773 129 182169 182170 1 269 Same + + 0.000000 0 0.000000 0.00000000 1.501985 3.148664 1.0485193 - - - hypothetical protein 1.420660 2.958975 1.0166375 693 Putative intracellular protease/amidase R intracellular protease 0.000000e+00 0 6.613673e-03 -1.554823e-03 -1.543111e-03 -1.097297e-01 5.326871e-01 0 33 FALSE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4881512 0.4869405 U 0.4686274 0.6162291 13773 129 182170 182171 1 149 Convergent + - 0.000000 0 0.000000 0.00000000 1.420660 2.958975 1.0166375 693 Putative intracellular protease/amidase R intracellular protease 1.425365 3.666016 1.1801157 - - - hypothetical protein 0.000000e+00 0 2.213331e-05 7.999150e-04 2.941238e-02 3.608887e-02 1.717508e-03 33 0 FALSE FALSE -15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177404 0.6507404 U 0.4686274 0.6162291 13773 129 182171 182172 1 88 Divergent - + 0.000000 0 0.000000 0.00000000 1.425365 3.666016 1.1801157 - - - hypothetical protein 1.405682 3.075150 1.0609670 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 0.000000e+00 0 3.874170e-04 1.189772e-03 3.823472e-02 6.054038e-02 3.420938e-02 0 39 TRUE FALSE -16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185284 0.6303843 U 0.4686274 0.6162291 13773 129 182172 182173 1 -3 Same + + 29.381693 0 40.241167 39.29899416 1.405682 3.075150 1.0609670 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 1.341828 3.199687 1.0975526 842 ABC-type multidrug transport system, permease component V membrane protein -4.302557e-04 34 4.077255e-03 5.008303e-03 1.044751e-01 2.928845e-01 2.198840e-01 V 39 34 FALSE FALSE -15 TRUE 2.1699775 2.0129683 0.5480306 2.2852741 0.7748967 0.5247796 0.5903711 0.5744992 Y 1.4497162 0.9327106 13773 129 182173 182174 1 28 Same + + 0.000000 0 0.000000 0.00000000 1.341828 3.199687 1.0975526 842 ABC-type multidrug transport system, permease component V membrane protein 1.348661 2.871389 0.9948434 2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases PR Rieske iron sulfur protein, putative 0.000000e+00 0 4.668110e-05 1.125578e-02 1.486599e-01 6.496596e-01 1.301089e-03 34 0 FALSE FALSE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7365839 0.6513850 U 0.4686274 0.6162291 13773 129 182174 182175 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.348661 2.871389 0.9948434 2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases PR Rieske iron sulfur protein, putative 1.468810 3.155015 1.0787608 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 1.443574e-02 -1.789261e-03 -2.621417e-02 -2.020357e-01 1.091007e+00 0 0 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4636660 0.4336700 U 0.4686274 0.6162291 13773 129 182175 182176 1 67 Divergent - + 0.000000 0 0.000000 0.00000000 1.468810 3.155015 1.0787608 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.289457 2.702952 0.8796424 605 Superoxide dismutase P superoxide dismutase (sod) 0.000000e+00 0 3.216725e-02 -2.820394e-03 5.358435e-02 -2.474790e-01 1.492785e+00 0 51 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4524862 0.4172295 U 0.4686274 0.6162291 13773 129 182176 182177 1 6 Convergent + - 0.000000 0 0.000000 0.00000000 1.289457 2.702952 0.8796424 605 Superoxide dismutase P superoxide dismutase (sod) 1.449946 3.274198 1.1307123 - - - conserved within P. aerophilum 0.000000e+00 0 2.575664e-02 2.342839e-04 -4.311152e-02 -8.002314e-02 1.099038e+00 51 0 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4979540 0.4327437 U 0.4686274 0.6162291 13773 129 182177 182178 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.449946 3.274198 1.1307123 - - - conserved within P. aerophilum 1.301833 2.960068 1.0674942 - - - hypothetical protein 0.000000e+00 0 2.193757e-02 2.163795e-04 8.006669e-02 -7.824202e-02 1.054444e+00 0 0 TRUE FALSE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4985931 0.4356615 U 0.4686274 0.6162291 13773 129 182178 182179 1 381 Convergent + - 0.000000 0 0.000000 0.00000000 1.301833 2.960068 1.0674942 - - - hypothetical protein 1.468183 3.259917 1.1217777 - - - hypothetical protein 0.000000e+00 0 2.767254e-02 -2.511192e-03 -6.471227e-02 -2.368994e-01 1.427869e+00 0 0 FALSE FALSE -13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4544155 0.4191329 U 0.4686274 0.6162291 13773 129 182179 182180 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.468183 3.259917 1.1217777 - - - hypothetical protein 1.564555 3.489860 1.1215241 - - - hypothetical protein 0.000000e+00 0 9.287418e-03 1.900044e-03 7.475750e-02 1.985718e-01 2.919151e-01 0 0 TRUE FALSE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5496485 0.5460473 U 0.4686274 0.6162291 13773 129 182180 182181 1 457 Same - - 0.000000 0 0.000000 0.00000000 1.564555 3.489860 1.1215241 - - - hypothetical protein 1.468870 3.689200 1.1531029 - - - P. aerophilum family 70 protein, 0.000000e+00 0 9.155624e-03 1.977699e-03 1.211726e-02 2.046443e-01 2.836809e-01 0 0 TRUE FALSE -15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5512857 0.5496363 U 0.4686274 0.6162291 13773 129 182181 182182 1 -28 Same - - 0.000000 0 0.000000 0.00000000 1.468870 3.689200 1.1531029 - - - P. aerophilum family 70 protein, 1.426247 3.206031 1.1410180 - - - P. aerophilum family 68 protein 0.000000e+00 0 1.816663e-03 -4.394630e-04 1.642944e-02 -4.088917e-02 1.736644e-01 0 0 TRUE FALSE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5088911 0.5866463 U 0.4686274 0.6162291 13773 129 182182 182183 1 400 Same - - 0.000000 0 0.000000 0.00000000 1.426247 3.206031 1.1410180 - - - P. aerophilum family 68 protein 1.241425 2.571199 0.8605797 2835 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.415916e-02 5.279758e-03 1.928221e-01 1.568834e-01 6.959375e-01 0 3 TRUE FALSE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5330784 0.4653071 U 0.4686274 0.6162291 13773 129 182183 182184 1 70 Same - - 0.000000 0 0.000000 0.00000000 1.241425 2.571199 0.8605797 2835 Uncharacterized conserved protein S conserved hypothetical protein 1.335959 3.045159 1.0548074 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 8.936528e-03 2.423747e-02 2.260104e-01 8.453424e-01 1.972483e-02 3 0 TRUE FALSE -18 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7931996 0.6377141 U 0.4686274 0.6162291 13773 129 182184 182185 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.335959 3.045159 1.0548074 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.663753 3.536700 1.1368364 - - - paREP2b 0.000000e+00 0 1.074492e-01 -2.451366e-02 -1.851982e-01 -8.028465e-01 3.219587e+00 0 0 TRUE FALSE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3827241 0.4003645 U 0.4686274 0.6162291 13773 129 182185 182186 1 945 Same - - 0.000000 0 0.000000 0.00000000 1.663753 3.536700 1.1368364 - - - paREP2b 1.346805 3.469529 1.1256084 - - - conserved within P. aerophilum 0.000000e+00 0 1.004563e-01 -2.221037e-02 -3.256971e-01 -7.543864e-01 3.037704e+00 0 0 TRUE FALSE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3848672 0.4009112 U 0.4686274 0.6162291 13773 129 182186 182187 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.346805 3.469529 1.1256084 - - - conserved within P. aerophilum 1.728611 3.784987 1.1057463 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein, conjectural 0.000000e+00 0 1.457764e-01 -2.899379e-02 -1.508832e-01 -7.851024e-01 3.172937e+00 0 2 TRUE FALSE -21 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3836776 0.4006378 U 0.4686274 0.6162291 13773 129 182187 182188 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.728611 3.784987 1.1057463 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein, conjectural 1.569314 3.465663 1.0367159 - - - hypothetical protein 0.000000e+00 0 2.537574e-02 3.268986e-02 2.431078e-01 7.873607e-01 3.170203e-02 2 0 TRUE FALSE -22 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7814434 0.6317872 U 0.4686274 0.6162291 13773 129 182188 182189 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.569314 3.465663 1.0367159 - - - hypothetical protein 1.797613 3.734510 1.0337825 - - - hypothetical protein 0.000000e+00 0 5.212041e-02 4.082655e-02 7.671867e-01 7.953698e-01 3.535439e-02 0 0 TRUE FALSE -23 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7837787 0.6298812 U 0.4686274 0.6162291 13773 129 182189 182190 1 31 Divergent - + 0.000000 0 0.000000 0.00000000 1.797613 3.734510 1.0337825 - - - hypothetical protein 1.518653 3.413084 1.1125429 - - - P. aerophilum family 321 protein 0.000000e+00 0 7.781833e-02 2.328691e-02 9.711295e-05 6.075530e-01 1.425743e-01 0 0 TRUE FALSE -24 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7230470 0.5949759 U 0.4686274 0.6162291 13773 129 182190 182191 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.518653 3.413084 1.1125429 - - - P. aerophilum family 321 protein 1.413417 3.353768 1.1497563 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein 0.000000e+00 0 1.107478e-02 -2.554306e-03 -1.695415e-02 -1.717714e-01 7.980262e-01 0 0 FALSE FALSE -23 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4725042 0.4555447 U 0.4686274 0.6162291 13773 129 182191 182192 1 103 Convergent + - 0.000000 0 0.000000 0.00000000 1.413417 3.353768 1.1497563 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein 1.664344 4.077084 1.2135068 - - - hypothetical protein 0.000000e+00 0 6.296445e-02 -8.087091e-03 3.768049e-02 -2.648590e-01 1.502177e+00 0 0 FALSE FALSE -22 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4488472 0.4169644 U 0.4686274 0.6162291 13773 129 182192 182193 1 414 Divergent - + 0.000000 0 0.000000 0.00000000 1.664344 4.077084 1.2135068 - - - hypothetical protein 1.576487 2.957800 1.0503235 - - - hypothetical protein 0.000000e+00 0 7.718861e-03 2.663883e-02 2.567840e-01 7.749847e-01 1.584159e-02 0 0 TRUE FALSE -23 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7749484 0.6399079 U 0.4686274 0.6162291 13773 129 182193 182194 1 140 Convergent + - 0.000000 0 0.000000 0.00000000 1.576487 2.957800 1.0503235 - - - hypothetical protein 1.526426 3.342765 1.1044466 - - - helix-turn-helix protein, conjectural 0.000000e+00 0 2.506031e-03 9.386230e-03 1.050422e-01 5.384634e-01 2.647176e-02 0 0 FALSE FALSE -22 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6911884 0.6347546 U 0.4686274 0.6162291 13773 129 182194 182195 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.526426 3.342765 1.1044466 - - - helix-turn-helix protein, conjectural 1.353259 3.048575 1.0744986 343 Queuine/archaeosine tRNA-ribosyltransferase J conserved hypothetical protein 0.000000e+00 0 2.998705e-02 -7.363352e-03 -5.519794e-02 -4.991374e-01 2.007126e+00 0 2 TRUE FALSE -23 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4055116 0.4080068 U 0.4686274 0.6162291 13773 129 182195 182196 1 116 Same - - 0.000000 0 0.000000 0.00000000 1.353259 3.048575 1.0744986 343 Queuine/archaeosine tRNA-ribosyltransferase J conserved hypothetical protein 1.474432 2.995250 1.0029450 - - - paREP2a 0.000000e+00 0 1.468287e-02 -2.260886e-03 -2.880556e-02 -2.349911e-01 1.142914e+00 2 0 TRUE FALSE -24 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4550501 0.4307435 U 0.4686274 0.6162291 13773 129 182196 182197 1 81 Divergent - + 0.000000 0 0.000000 0.00000000 1.474432 2.995250 1.0029450 - - - paREP2a 1.458822 3.134788 1.0787855 - - - paREP2b 0.000000e+00 0 2.436636e-04 1.711548e-04 2.153111e-02 5.103342e-02 2.081742e-02 0 0 TRUE FALSE -25 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187862 0.6371410 U 0.4686274 0.6162291 13773 129 182197 182198 1 228 Same + + 0.000000 0 0.000000 0.00000000 1.458822 3.134788 1.0787855 - - - paREP2b 1.422118 3.173101 1.0491304 - - - hypothetical protein 0.000000e+00 0 1.347206e-03 -2.174863e-04 2.023109e-02 -3.343132e-02 1.351395e-01 0 0 FALSE FALSE -24 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5110826 0.5970160 U 0.4686274 0.6162291 13773 129 182198 182199 1 -11 Convergent + - 0.000000 0 0.000000 0.00000000 1.422118 3.173101 1.0491304 - - - hypothetical protein 1.400321 3.124632 1.0309817 - - - paREP1 0.000000e+00 0 4.751086e-04 1.495156e-03 4.266701e-02 8.490001e-02 4.683919e-02 0 0 FALSE FALSE -23 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176820 0.6252488 U 0.4686274 0.6162291 13773 129 182199 182200 1 19 Same - - 0.000000 0 0.000000 0.00000000 1.400321 3.124632 1.0309817 - - - paREP1 1.541226 3.441231 1.1696707 - - - hypothetical protein 0.000000e+00 0 1.985431e-02 -4.587978e-03 -1.903646e-02 -3.016523e-01 1.297116e+00 0 0 TRUE FALSE -24 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4398443 0.4240379 U 0.4686274 0.6162291 13773 129 182200 182201 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.541226 3.441231 1.1696707 - - - hypothetical protein 1.396224 3.013035 1.0901031 - - - hypothetical protein 0.000000e+00 0 2.102555e-02 -4.955986e-03 -4.997359e-02 -3.287237e-01 1.384189e+00 0 0 TRUE FALSE -25 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4331939 0.4204509 U 0.4686274 0.6162291 13773 129 182201 182202 1 42 Same - - 0.000000 0 0.000000 0.00000000 1.396224 3.013035 1.0901031 - - - hypothetical protein 1.234520 2.873357 0.9860914 640 Predicted transcriptional regulators K conserved hypothetical protein 0.000000e+00 0 2.614814e-02 1.196462e-02 2.723448e-01 4.538349e-01 2.886073e-01 0 0 TRUE FALSE -26 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6580607 0.5474398 U 0.4686274 0.6162291 13773 129 182202 182203 1 216 Same - - 0.000000 0 0.000000 0.00000000 1.234520 2.873357 0.9860914 640 Predicted transcriptional regulators K conserved hypothetical protein 1.525977 3.294887 1.1599664 - - - conserved within P. aerophilum 0.000000e+00 0 8.494710e-02 -1.617527e-02 -2.737040e-01 -6.498611e-01 2.715034e+00 0 0 TRUE FALSE -27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3900692 0.4023480 U 0.4686274 0.6162291 13773 129 182203 182204 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.525977 3.294887 1.1599664 - - - conserved within P. aerophilum 1.560109 3.485877 1.1296016 - - - hypothetical protein 0.000000e+00 0 1.165007e-03 8.108515e-03 1.314330e-01 5.093506e-01 1.564899e-02 0 0 TRUE FALSE -28 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6760583 0.6400352 U 0.4686274 0.6162291 13773 129 182204 182205 1 35 Divergent - + 0.000000 0 0.000000 0.00000000 1.560109 3.485877 1.1296016 - - - hypothetical protein 1.380429 2.941854 1.0070036 402 Cytosine deaminase and related metal-dependent hydrolases FR chlorohydrolase, conjectural 0.000000e+00 0 3.228504e-02 -7.714951e-03 -8.669405e-02 -4.519590e-01 1.847346e+00 0 0 TRUE FALSE -29 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4119646 0.4103518 U 0.4686274 0.6162291 13773 129 182205 182206 1 280 Convergent + - 0.000000 0 0.000000 0.00000000 1.380429 2.941854 1.0070036 402 Cytosine deaminase and related metal-dependent hydrolases FR chlorohydrolase, conjectural 1.633383 3.486133 1.0582950 - - - hypothetical protein 0.000000e+00 0 6.398582e-02 -1.291476e-02 -5.894439e-02 -5.316640e-01 2.239651e+00 0 0 FALSE FALSE -28 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4007451 0.4053969 U 0.4686274 0.6162291 13773 129 182206 182207 1 -6 Same - - 0.000000 0 0.000000 0.00000000 1.633383 3.486133 1.0582950 - - - hypothetical protein 1.604843 3.417790 1.0921328 - - - conserved within P. aerophilum 0.000000e+00 0 8.145236e-04 2.792644e-02 3.229496e-01 7.996058e-01 1.913643e-03 0 0 TRUE FALSE -29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7856528 0.6504429 U 0.4686274 0.6162291 13773 129 182207 182208 1 119 Same - - 0.000000 0 0.000000 0.00000000 1.604843 3.417790 1.0921328 - - - conserved within P. aerophilum 1.377877 3.711398 1.1443552 - - - hypothetical protein 0.000000e+00 0 5.151374e-02 -1.128107e-02 -1.572364e-01 -5.250343e-01 2.173531e+00 0 0 TRUE FALSE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4016587 0.4062445 U 0.4686274 0.6162291 13773 129 182208 182209 1 57 Same - - 0.000000 0 0.000000 0.00000000 1.377877 3.711398 1.1443552 - - - hypothetical protein 1.473586 3.524036 1.1500775 - - - hypothetical protein 0.000000e+00 0 9.160268e-03 -1.631556e-03 -1.081319e-02 -1.814762e-01 8.159510e-01 0 0 TRUE FALSE -31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4695547 0.4534446 U 0.4686274 0.6162291 13773 129 182209 182210 1 469 Divergent - + 0.000000 0 0.000000 0.00000000 1.473586 3.524036 1.1500775 - - - hypothetical protein 1.466632 3.291776 1.1006073 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 0.000000e+00 0 4.835269e-05 3.382143e-04 2.403117e-02 7.129424e-02 4.255485e-03 0 3 TRUE FALSE -32 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180376 0.6470653 U 0.4686274 0.6162291 13773 129 182210 182211 1 -13 Same + + 2.856470 0 5.519058 5.36698852 1.466632 3.291776 1.1006073 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 1.373493 3.438268 1.1729468 842 ABC-type multidrug transport system, permease component V ABC-2 type transport system, membrane protein 1.392617e-01 3 8.675026e-03 -1.187166e-03 2.167811e-02 -1.507519e-01 7.641148e-01 V 3 4 FALSE FALSE -31 TRUE 2.8950318 1.7774688 0.5480306 2.8617306 0.7136133 1.0767792 0.4766485 0.4581595 Y 1.4497162 0.9037102 13773 129 182211 182212 1 108 Convergent + - 0.000000 0 0.000000 0.00000000 1.373493 3.438268 1.1729468 842 ABC-type multidrug transport system, permease component V ABC-2 type transport system, membrane protein 1.378311 2.964545 1.0125668 780 Enzyme related to GTP cyclohydrolase I R GTP cyclohydrolase I, conjectural 0.000000e+00 0 2.321343e-05 5.693124e-03 8.545595e-02 3.803060e-01 1.717508e-03 4 0 FALSE FALSE -30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6252960 0.6507404 U 0.4686274 0.6162291 13773 129 182212 182213 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.378311 2.964545 1.0125668 780 Enzyme related to GTP cyclohydrolase I R GTP cyclohydrolase I, conjectural 1.443530 3.111477 1.0882815 366 Glycosidases G hypothetical protein 0.000000e+00 0 4.253620e-03 5.746045e-04 1.404957e-02 -1.235651e-02 3.807354e-01 0 1 TRUE FALSE -31 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176872 0.5167658 U 0.4686274 0.6162291 13773 129 182213 182214 1 6 Same + + 0.000000 0 0.000000 0.00000000 1.443530 3.111477 1.0882815 366 Glycosidases G hypothetical protein 1.409223 3.062784 1.0747422 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 1.176981e-03 3.315558e-04 2.897329e-02 -6.631488e-03 1.161120e-01 0 1 0 FALSE FALSE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5194416 0.6016448 N 0.5492530 0.6245624 13773 129 182214 182215 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.409223 3.062784 1.0747422 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.371447 2.987636 1.0486565 44 Dihydroorotase and related cyclic amidohydrolases F dihydroorotase (pyrC) 0.000000e+00 0 1.427072e-03 3.371298e-03 7.187092e-02 2.085235e-01 1.099205e-01 0 0 56 FALSE FALSE -29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5532978 0.6030494 N 0.5492530 0.6245624 13773 129 182215 182216 1 41 Convergent + - 0.000000 0 0.000000 -0.27443685 1.371447 2.987636 1.0486565 44 Dihydroorotase and related cyclic amidohydrolases F dihydroorotase (pyrC) 1.504933 3.731539 1.2325215 370 Fe2+ transport system protein B P iron (II) transporter (feoB-2) part 1, conjectural, authentic frameshift 1.157192e-02 3 1.781856e-02 -4.280318e-03 -3.826041e-02 -3.505394e-01 1.415059e+00 0 56 3 FALSE FALSE -28 FALSE 0.4469764 0.2578620 0.5480306 0.4469764 0.7136133 0.6089544 0.4278252 0.4195054 N 0.5492530 0.5526269 13773 129 182216 182217 1 45 Same - - 0.000000 0 0.000000 0.00000000 1.504933 3.731539 1.2325215 370 Fe2+ transport system protein B P iron (II) transporter (feoB-2) part 1, conjectural, authentic frameshift 1.424185 3.131784 1.0809630 370 Fe2+ transport system protein B P iron (II) transporter (feoB-2) part 2, conjectural, authentic frameshift 0.000000e+00 0 6.520171e-03 -1.456694e-03 -1.694084e-03 -9.867953e-02 5.204355e-01 P 3 0 TRUE FALSE -29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4919440 0.4892985 Y 1.4497162 0.7118045 13773 129 182217 182218 1 270 Divergent - + 0.000000 0 0.000000 0.00000000 1.424185 3.131784 1.0809630 370 Fe2+ transport system protein B P iron (II) transporter (feoB-2) part 2, conjectural, authentic frameshift 1.501808 3.371736 1.1388806 3839 ABC-type sugar transport systems, ATPase components G thiamine transport ATP-binding protein 0.000000e+00 0 6.025308e-03 -1.371678e-03 9.274432e-03 -9.473798e-02 4.898926e-01 0 0 0 TRUE FALSE -30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4937993 0.4941753 N 0.5492530 0.6245624 13773 129 182218 182219 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.501808 3.371736 1.1388806 3839 ABC-type sugar transport systems, ATPase components G thiamine transport ATP-binding protein 1.392549 3.461761 1.2070745 1178 ABC-type Fe3+ transport system, permease component P conserved hypothetical protein 0.000000e+00 0 1.193766e-02 -2.966652e-03 -1.161046e-02 -2.473494e-01 9.908117e-01 0 0 1 FALSE FALSE -29 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4526485 0.4400938 N 0.5492530 0.6245624 13773 129 182219 182220 1 112 Same - - 0.000000 0 0.000000 0.00000000 1.392549 3.461761 1.2070745 1178 ABC-type Fe3+ transport system, permease component P conserved hypothetical protein 1.406052 3.152907 1.0675745 4143 ABC-type thiamine transport system, periplasmic component H thiamine-binding periplasmic protein 1.352502e-03 1 1.823367e-04 2.668068e-03 4.836081e-02 1.679624e-01 1.642646e-02 0 1 7 TRUE FALSE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4789292 0.5380449 0.6394805 N 0.5492530 0.6245624 13773 129 182220 182221 1 113 Same - - 0.000000 0 0.000000 -3.11918074 1.406052 3.152907 1.0675745 4143 ABC-type thiamine transport system, periplasmic component H thiamine-binding periplasmic protein 1.352298 2.940505 1.0333425 480 Translation elongation factors (GTPases) J translation elongation factor aEF-2 4.074972e-04 7 2.889475e-03 4.493076e-03 9.298873e-02 2.683629e-01 1.717508e-01 0 7 61 TRUE FALSE -31 TRUE 0.4469764 0.1892484 0.5480306 0.4469764 0.7596462 0.4531085 0.5778579 0.5873404 N 0.5492530 0.5309276 13773 129 182221 182222 1 48 Same - - 0.000000 0 0.000000 -2.96231719 1.352298 2.940505 1.0333425 480 Translation elongation factors (GTPases) J translation elongation factor aEF-2 1.371788 2.918466 1.0510956 422 Thiamine biosynthesis protein ThiC H thiamine biosynthesis protein (thiC) 3.077095e-03 28 3.798669e-04 7.888433e-03 1.041266e-01 4.944455e-01 1.415059e-02 0 61 28 TRUE FALSE -32 TRUE 0.4469764 0.1903649 0.5480306 0.4469764 0.7759129 0.5152567 0.6707372 0.6408729 N 0.5492530 0.5312819 13773 129 182222 182223 1 148 Divergent - + 0.000000 0 0.000000 0.00000000 1.371788 2.918466 1.0510956 422 Thiamine biosynthesis protein ThiC H thiamine biosynthesis protein (thiC) 1.322501 3.110858 1.0554832 - - - hypothetical protein 0.000000e+00 0 2.429214e-03 1.026041e-02 1.668017e-01 5.742907e-01 5.881463e-02 28 0 TRUE FALSE -33 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7099507 0.6209502 U 0.4686274 0.6162291 13773 129 182223 182224 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.322501 3.110858 1.0554832 - - - hypothetical protein 1.493534 3.424200 1.1112714 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 2.925215e-02 -5.431600e-03 -8.044946e-02 -4.078692e-01 1.816185e+00 0 1 TRUE TRUE -32 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4180357 0.4105042 U 0.4686274 0.6162291 13773 129 182224 182225 1 35 Same + + 0.000000 0 0.000000 0.00000000 1.493534 3.424200 1.1112714 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.476605 3.353997 1.0626622 - - - hypothetical protein 0.000000e+00 0 2.865628e-04 1.062478e-03 3.026501e-02 1.521585e-01 1.623033e-02 1 0 TRUE TRUE -31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5310658 0.6396093 U 0.4686274 0.6162291 13773 129 182225 182226 1 110 Convergent + - 0.000000 0 0.000000 0.00000000 1.476605 3.353997 1.0626622 - - - hypothetical protein 1.462036 3.265655 1.1182808 2073 Cobalamin biosynthesis protein CbiG H cobalamin biosynthesis protein G (cbiG) 0.000000e+00 0 2.122741e-04 2.683367e-04 2.254851e-02 6.666474e-02 1.702194e-02 0 5 TRUE TRUE -30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182033 0.6393080 U 0.4686274 0.6162291 13773 129 182226 182227 1 -13 Same - - 2.856470 0 5.519058 5.50103953 1.462036 3.265655 1.1182808 2073 Cobalamin biosynthesis protein CbiG H cobalamin biosynthesis protein G (cbiG) 1.517538 3.393530 1.0988521 2241 Precorrin-6B methylase 1 H cobalamin biosynthesis precorrin-6Y methylase (cbiE) 5.466718e-02 5 3.080541e-03 7.039849e-04 3.979218e-02 1.219101e-01 1.642022e-01 H 5 8 FALSE TRUE -31 TRUE 2.8950318 1.7833824 0.5480306 2.8617306 0.7448207 0.8664027 0.5224030 0.5889325 Y 1.4497162 0.9043638 13773 129 182227 182228 1 93 Divergent - + 0.000000 0 0.000000 0.00000000 1.517538 3.393530 1.0988521 2241 Precorrin-6B methylase 1 H cobalamin biosynthesis precorrin-6Y methylase (cbiE) 1.457043 3.541714 1.1477174 - - - hypothetical protein 0.000000e+00 0 3.659652e-03 3.737570e-04 1.407789e-02 9.026928e-02 2.092202e-01 8 0 FALSE TRUE -32 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178258 0.5762640 U 0.4686274 0.6162291 13773 129 182228 182229 1 41 Same + + 0.000000 0 0.000000 0.00000000 1.457043 3.541714 1.1477174 - - - hypothetical protein 1.405229 3.466357 1.1312410 - - - hypothetical protein 0.000000e+00 0 2.684742e-03 -2.608505e-04 2.301865e-02 -5.370451e-02 2.596853e-01 0 0 TRUE TRUE -31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5056379 0.5580942 U 0.4686274 0.6162291 13773 129 182229 182230 1 -12 Same + + 0.000000 0 0.000000 0.00000000 1.405229 3.466357 1.1312410 - - - hypothetical protein 1.526346 3.344988 1.1320033 2082 Precorrin isomerase H cobalamin biosynthesis putative precorrin-8X methylmutase (precorrin isomerase) 0.000000e+00 0 1.466938e-02 -3.460139e-03 -1.086428e-02 -2.366874e-01 1.034053e+00 0 2 TRUE TRUE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4545745 0.4366685 U 0.4686274 0.6162291 13773 129 182230 182231 1 -10 Same + + 2.856470 0 5.519058 5.51905803 1.526346 3.344988 1.1320033 2082 Precorrin isomerase H cobalamin biosynthesis putative precorrin-8X methylmutase (precorrin isomerase) 1.568320 3.456339 1.1454439 1010 Precorrin-3B methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 3.639057e-02 2 1.761831e-03 8.764089e-03 1.436632e-01 5.247410e-01 2.059655e-02 H 2 20 TRUE TRUE -29 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 0.7784366 0.6859261 0.6372565 Y 1.4497162 0.9052318 13773 129 182231 182232 1 -3 Same + + 11.567035 0 19.410157 19.39213844 1.568320 3.456339 1.1454439 1010 Precorrin-3B methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 1.408499 3.050689 1.0536403 1903 Cobalamin biosynthesis protein CbiD H cobalamin biosynthesis protein D (cbiD) 6.865623e-02 12 2.554284e-02 -5.015468e-03 -6.795238e-02 -2.620636e-01 1.271027e+00 H 20 12 TRUE TRUE -28 TRUE 2.6171082 1.9131714 0.5480306 2.6057102 0.7776747 0.9097341 0.4493515 0.4254077 Y 1.4497162 0.9203054 13773 129 182232 182233 1 -3 Same + + 10.650744 0 17.107572 17.04873136 1.408499 3.050689 1.0536403 1903 Cobalamin biosynthesis protein CbiD H cobalamin biosynthesis protein D (cbiD) 1.448956 3.277642 1.1292017 2242 Precorrin-6B methylase 2 H cobalamin biosynthesis precorrin-8W decarboxylase (cbiT) 9.667394e-02 12 1.636749e-03 1.045365e-04 1.730264e-02 -2.389256e-02 1.604916e-01 H 12 16 TRUE TRUE -27 TRUE 2.6560654 1.8903666 0.5480306 2.6465219 0.7776747 1.0018434 0.5141330 0.5898600 Y 1.4497162 0.9177845 13773 129 182233 182234 1 -7 Same + + 14.091162 0 23.087621 22.65837586 1.448956 3.277642 1.1292017 2242 Precorrin-6B methylase 2 H cobalamin biosynthesis precorrin-8W decarboxylase (cbiT) 1.472419 3.360879 1.1134450 2243 Precorrin-2 methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 7.274937e-02 16 5.505107e-04 -5.124210e-05 2.124615e-02 2.092697e-02 4.584791e-02 H 16 21 TRUE TRUE -26 TRUE 2.5860702 1.9319849 0.5480306 2.5391984 0.7783446 0.9280743 0.5175976 0.6256408 Y 1.4497162 0.9223220 13773 129 182234 182235 1 -15 Same + + 28.581401 0 38.247477 37.95393937 1.472419 3.360879 1.1134450 2243 Precorrin-2 methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 1.296201 2.809936 0.9893070 2875 Precorrin-4 methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 1.957413e-01 21 3.105261e-02 -3.263039e-03 4.262531e-02 -2.733723e-01 1.536230e+00 H 21 32 TRUE TRUE -25 TRUE 2.1781197 2.0108049 0.5480306 2.3077761 0.7775415 1.1384430 0.4466323 0.4159632 Y 1.4497162 0.9324739 13773 129 182235 182236 1 917 Convergent + - 0.000000 0 0.000000 0.00000000 1.296201 2.809936 0.9893070 2875 Precorrin-4 methylase H cobalamin biosynthesis precorrin-3 methylase (cbiF) 1.546247 3.560338 1.0707511 - - - hypothetical protein 0.000000e+00 0 6.252295e-02 -1.472059e-02 -1.896934e-01 -6.987806e-01 2.842963e+00 32 0 TRUE TRUE -24 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3872385 0.4015948 U 0.4686274 0.6162291 13773 129 182236 182237 1 112 Divergent - + 0.000000 0 0.000000 0.00000000 1.546247 3.560338 1.0707511 - - - hypothetical protein 1.539640 3.910282 1.1929423 - - - hypothetical protein 0.000000e+00 0 4.365476e-05 8.370610e-03 1.155370e-01 5.225370e-01 4.617716e-04 0 0 FALSE TRUE -25 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6851824 0.6534780 U 0.4686274 0.6162291 13773 129 182237 182238 1 309 Convergent + - 0.000000 0 0.000000 0.00000000 1.539640 3.910282 1.1929423 - - - hypothetical protein 1.448568 3.121507 1.0566470 5493 Uncharacterized conserved protein containing a coiled-coil domain S conserved hypothetical protein 0.000000e+00 0 8.294095e-03 -2.492845e-04 -1.933292e-03 4.864623e-02 4.146055e-01 0 0 TRUE TRUE -24 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187590 0.5098051 U 0.4686274 0.6162291 13773 129 182238 182239 1 432 Same - - 0.000000 0 0.000000 0.00000000 1.448568 3.121507 1.0566470 5493 Uncharacterized conserved protein containing a coiled-coil domain S conserved hypothetical protein 1.467752 3.194031 1.0720453 - - - P. aerophilum family 1964 protein 0.000000e+00 0 3.680404e-04 -4.621318e-05 2.085675e-02 1.677456e-02 3.142933e-02 0 0 FALSE TRUE -25 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179979 0.6319821 U 0.4686274 0.6162291 13773 129 182239 182240 1 324 Same - - 0.000000 0 0.000000 0.00000000 1.467752 3.194031 1.0720453 - - - P. aerophilum family 1964 protein 1.437078 3.203928 1.0837394 3842 ABC-type spermidine/putrescine transport systems, ATPase components E ABC transporter, ATP-binding protein 0.000000e+00 0 9.409300e-04 -2.341875e-04 1.784024e-02 -1.074326e-02 8.371319e-02 0 1 FALSE TRUE -26 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182978 0.6128672 U 0.4686274 0.6162291 13773 129 182240 182241 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.437078 3.203928 1.0837394 3842 ABC-type spermidine/putrescine transport systems, ATPase components E ABC transporter, ATP-binding protein 1.504789 3.152817 1.0542587 - - - paREP2b 0.000000e+00 0 4.584744e-03 -7.643619e-04 1.852055e-02 -2.346730e-02 3.366315e-01 1 0 FALSE TRUE -27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5142003 0.5289643 U 0.4686274 0.6162291 13773 129 182241 182242 1 111 Divergent - + 0.000000 0 0.000000 0.00000000 1.504789 3.152817 1.0542587 - - - paREP2b 1.221381 2.516647 1.0124477 - - - paREP2a 0.000000e+00 0 8.032007e-02 -1.228166e-02 4.251016e-03 -5.356309e-01 2.355978e+00 0 0 FALSE TRUE -28 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4000583 0.4044182 U 0.4686274 0.6162291 13773 129 182242 182243 1 39 Convergent + - 0.000000 0 0.000000 0.00000000 1.221381 2.516647 1.0124477 - - - paREP2a 1.463632 3.691602 1.2424555 609 ABC-type Fe3+-siderophore transport system, permease component P iron (III) dicitrate transport system, permease protein, putative 0.000000e+00 0 5.868580e-02 -2.815179e-03 -1.461521e-01 -2.099612e-01 1.461074e+00 0 40 TRUE TRUE -27 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4617680 0.4180349 U 0.4686274 0.6162291 13773 129 182243 182244 1 -3 Same - - 2.079442 0 2.079442 1.90954250 1.463632 3.691602 1.2424555 609 ABC-type Fe3+-siderophore transport system, permease component P iron (III) dicitrate transport system, permease protein, putative 1.400658 3.141147 1.0986745 614 ABC-type Fe3+-hydroxamate transport system, periplasmic component P conserved hypothetical protein 5.325482e-03 4 3.965679e-03 -6.209511e-04 1.963358e-02 -8.682484e-02 3.883499e-01 P 40 4 FALSE TRUE -28 TRUE 2.9335626 1.6511628 0.5480306 2.9479804 0.7323301 0.5465141 0.4962434 0.5144469 Y 1.4497162 0.8882948 13773 129 182244 182245 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.400658 3.141147 1.0986745 614 ABC-type Fe3+-hydroxamate transport system, periplasmic component P conserved hypothetical protein 1.378782 3.018022 1.0657840 612 Predicted Zn-dependent peptidases R protease 0.000000e+00 0 4.785895e-04 3.683877e-03 7.066320e-02 2.446306e-01 3.225098e-02 4 0 FALSE TRUE -29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5678479 0.6314500 U 0.4686274 0.6162291 13773 129 182245 182246 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.378782 3.018022 1.0657840 612 Predicted Zn-dependent peptidases R protease 1.400355 3.027440 1.0162877 1475 Predicted transcriptional regulators K paREP1 0.000000e+00 0 4.654111e-04 3.705900e-03 5.729392e-02 2.473588e-01 3.061829e-02 0 0 FALSE TRUE -30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5682590 0.6326945 U 0.4686274 0.6162291 13773 129 182246 182247 1 331 Convergent + - 0.000000 0 0.000000 0.00000000 1.400355 3.027440 1.0162877 1475 Predicted transcriptional regulators K paREP1 1.327839 2.844393 1.0072554 2109 ATP:corrinoid adenosyltransferase H cob(I)alamin adenosyltransferase 0.000000e+00 0 5.258610e-03 6.305907e-03 1.266202e-01 3.652708e-01 2.092202e-01 0 0 26 TRUE TRUE -29 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6175701 0.5762640 N 0.5492530 0.6245624 13773 129 182247 182248 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.327839 2.844393 1.0072554 2109 ATP:corrinoid adenosyltransferase H cob(I)alamin adenosyltransferase 1.345382 3.023100 1.0461985 1267 Phosphatidylglycerophosphatase A and related proteins I conserved hypothetical protein 1.190151e-02 2 3.077495e-04 1.309810e-02 1.636572e-01 7.070407e-01 4.458099e-03 0 26 2 FALSE TRUE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.6132969 0.7558692 0.6467962 N 0.5492530 0.6245624 13773 129 182248 182249 1 -10 Same - - 2.079442 0 2.079442 2.01881692 1.345382 3.023100 1.0461985 1267 Phosphatidylglycerophosphatase A and related proteins I conserved hypothetical protein 1.462729 3.282381 1.1304335 2038 NaMN:DMB phosphoribosyltransferase H conserved hypothetical protein 4.465466e-02 2 1.377038e-02 -1.201751e-03 -2.152711e-02 -1.662166e-01 1.027819e+00 0 2 15 FALSE TRUE -31 TRUE 2.9335626 1.6548846 0.5480306 2.9479804 0.6838149 0.8246830 0.4731627 0.4370851 N 0.5492530 0.8432983 13773 129 182249 182250 1 248 Divergent - + 0.000000 0 0.000000 -0.24283734 1.462729 3.282381 1.1304335 2038 NaMN:DMB phosphoribosyltransferase H conserved hypothetical protein 1.399430 3.037518 1.0139771 2102 Predicted ATPases of PP-loop superfamily R conserved hypothetical protein 4.465466e-02 2 4.006726e-03 -5.890526e-04 2.038094e-02 -8.808058e-02 4.018567e-01 15 2 FALSE TRUE -32 FALSE 0.4469764 0.2674215 0.5480306 0.4469764 0.6838149 0.8246830 0.4959484 0.5122596 U 0.4686274 0.5468830 13773 129 182250 182251 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.399430 3.037518 1.0139771 2102 Predicted ATPases of PP-loop superfamily R conserved hypothetical protein 1.431573 3.224095 1.0774819 367 Asparagine synthase (glutamine-hydrolyzing) E asparagine synthetase (asnB) 7.508473e-04 2 1.033133e-03 1.029911e-03 2.692036e-02 4.141102e-02 1.099205e-01 2 2 TRUE TRUE -31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4618072 0.5182916 0.6030494 U 0.4686274 0.6162291 13773 129 182251 182252 1 -55 Same + + 0.000000 0 0.000000 0.00000000 1.431573 3.224095 1.0774819 367 Asparagine synthase (glutamine-hydrolyzing) E asparagine synthetase (asnB) 1.471153 3.247761 1.1109617 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E cobC aminotransferase, conjectural 6.839682e-03 2 1.566623e-03 -3.916549e-04 1.615233e-02 -2.679100e-02 1.396912e-01 E 2 14 TRUE TRUE -30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5692508 0.5131308 0.5958874 Y 1.4497162 0.7118045 13773 129 182252 182253 1 -13 Same + + 0.000000 0 0.000000 -0.07410797 1.471153 3.247761 1.1109617 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E cobC aminotransferase, conjectural 1.468144 3.558645 1.2286191 368 Cobalamin-5-phosphate synthase H cobalamin (5'-phosphate) synthase (cobS) 2.290293e-02 1 9.055257e-06 3.310091e-04 2.432892e-02 6.910377e-02 7.633367e-04 0 14 1 TRUE TRUE -29 TRUE 0.4469764 0.2976889 0.5480306 0.4469764 0.6329203 0.6966823 0.5181385 0.6522016 N 0.5492530 0.5651364 13773 129 182253 182254 1 -25 Same + + 0.000000 0 0.000000 0.00000000 1.468144 3.558645 1.2286191 368 Cobalamin-5-phosphate synthase H cobalamin (5'-phosphate) synthase (cobS) 1.471274 3.561700 1.2055844 1270 Cobalamin biosynthesis protein CobD/CbiB H cobalamin biosynthesis protein B (cbiB) 0.000000e+00 0 9.797626e-06 3.330346e-04 2.492281e-02 6.929519e-02 8.063333e-04 H 1 0 TRUE TRUE -28 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181256 0.6521082 Y 1.4497162 0.7118045 13773 129 182254 182255 1 412 Same + + 0.000000 0 0.000000 0.00000000 1.471274 3.561700 1.2055844 1270 Cobalamin biosynthesis protein CobD/CbiB H cobalamin biosynthesis protein B (cbiB) 1.250126 2.673319 1.0264816 - - - paREP4 0.000000e+00 0 4.890663e-02 -4.001449e-03 7.581947e-02 -2.744090e-01 1.601594e+00 0 0 TRUE TRUE -27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4462869 0.4147331 U 0.4686274 0.6162291 13773 129 182255 182256 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.250126 2.673319 1.0264816 - - - paREP4 1.308939 2.982302 1.0537593 640 Predicted transcriptional regulators K metal ion binding transcriptional regulator, conjectural 0.000000e+00 0 3.458988e-03 2.867131e-02 3.046337e-01 9.149492e-01 3.769564e-03 0 2 TRUE TRUE -26 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8065938 0.6475210 U 0.4686274 0.6162291 13773 129 182256 182257 1 38 Convergent + - 0.000000 0 0.000000 0.00000000 1.308939 2.982302 1.0537593 640 Predicted transcriptional regulators K metal ion binding transcriptional regulator, conjectural 1.557097 3.247890 1.0242760 - - - hypothetical protein 0.000000e+00 0 6.158267e-02 -1.505804e-02 -1.784846e-01 -7.102053e-01 2.866304e+00 2 0 TRUE TRUE -25 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3862913 0.4013896 U 0.4686274 0.6162291 13773 129 182257 182258 1 53 Same - - 0.000000 0 0.000000 0.00000000 1.557097 3.247890 1.0242760 - - - hypothetical protein 1.363677 2.905040 0.9913397 2041 Sulfite oxidase and related enzymes R sulfite oxidase, conjectural 0.000000e+00 0 3.741161e-02 -9.272007e-03 -9.650896e-02 -5.401562e-01 2.164489e+00 0 11 FALSE TRUE -26 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3993701 0.4064935 U 0.4686274 0.6162291 13773 129 182258 182259 1 173 Same - - 0.000000 0 0.000000 0.00000000 1.363677 2.905040 0.9913397 2041 Sulfite oxidase and related enzymes R sulfite oxidase, conjectural 1.852573 4.134321 1.1736360 - - - paREP1, degenerate 0.000000e+00 0 2.390202e-01 -3.519006e-02 -1.530090e-03 -7.018245e-01 2.892349e+00 11 0 FALSE TRUE -27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3870019 0.4012529 U 0.4686274 0.6162291 13773 129 182259 182260 1 301 Divergent - + 0.000000 0 0.000000 0.00000000 1.852573 4.134321 1.1736360 - - - paREP1, degenerate 1.562327 3.395231 1.0694367 - - - conserved protein, degenerate 0.000000e+00 0 8.424302e-02 4.450464e-02 1.636270e-01 7.805695e-01 4.519295e-02 0 0 FALSE TRUE -28 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7791163 0.6259433 U 0.4686274 0.6162291 13773 129 182260 182261 1 -24 Same + + 0.000000 0 0.000000 0.00000000 1.562327 3.395231 1.0694367 - - - conserved protein, degenerate 1.413053 3.176271 1.0744540 - - - paREP6 0.000000e+00 0 2.228279e-02 -4.253219e-03 -5.651136e-02 -2.237071e-01 1.142914e+00 0 0 TRUE TRUE -27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4584678 0.4307435 U 0.4686274 0.6162291 13773 129 182261 182262 1 109 Same + + 0.000000 0 0.000000 0.00000000 1.413053 3.176271 1.0744540 - - - paREP6 1.371771 2.752137 0.9510669 - - - hypothetical protein 0.000000e+00 0 1.704189e-03 3.052704e-03 6.879736e-02 1.847063e-01 1.306631e-01 0 0 TRUE TRUE -26 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5438720 0.5980793 U 0.4686274 0.6162291 13773 129 182262 182263 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.371771 2.752137 0.9510669 - - - hypothetical protein 1.409269 2.989984 1.0334624 - - - hypothetical protein 0.000000e+00 0 1.406074e-03 3.354007e-03 4.836034e-02 2.065533e-01 1.073908e-01 0 0 TRUE TRUE -25 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5519505 0.6039545 U 0.4686274 0.6162291 13773 129 182263 182264 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.409269 2.989984 1.0334624 - - - hypothetical protein 1.551629 3.382767 1.0859244 - - - hypothetical protein 0.000000e+00 0 2.026641e-02 -4.222359e-03 -7.622482e-03 -2.384061e-01 1.136359e+00 0 0 TRUE TRUE -24 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4540966 0.4313682 U 0.4686274 0.6162291 13773 129 182264 182265 1 548 Same + + 0.000000 0 0.000000 0.00000000 1.551629 3.382767 1.0859244 - - - hypothetical protein 1.397574 3.405507 1.1496118 - - - conserved within P. aerophilum 0.000000e+00 0 2.373281e-02 -5.394562e-03 -6.049656e-02 -3.318200e-01 1.418713e+00 0 0 TRUE TRUE -23 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4320181 0.4194119 U 0.4686274 0.6162291 13773 129 182265 182266 1 203 Same + + 0.000000 0 0.000000 0.00000000 1.397574 3.405507 1.1496118 - - - conserved within P. aerophilum 1.659595 3.821605 1.1781356 - - - hypothetical protein 0.000000e+00 0 6.865472e-02 -1.120514e-02 -7.548848e-03 -4.170770e-01 1.912585e+00 0 0 TRUE TRUE -22 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4161024 0.4095588 U 0.4686274 0.6162291 13773 129 182266 182267 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.659595 3.821605 1.1781356 - - - hypothetical protein 1.291274 2.820649 0.9409501 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 1.356603e-01 -3.333707e-02 -4.140232e-01 -9.004252e-01 3.602130e+00 0 2 TRUE TRUE -21 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3791352 0.3993385 U 0.4686274 0.6162291 13773 129 182267 182268 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.291274 2.820649 0.9409501 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.377136 3.051858 1.0227254 - - - P. aerophilum family 1964 protein 0.000000e+00 0 7.372302e-03 1.188995e-02 1.086532e-01 5.845769e-01 1.224731e-01 2 0 TRUE TRUE -20 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7152163 0.6002255 U 0.4686274 0.6162291 13773 129 182268 182269 1 426 Same + + 0.000000 0 0.000000 0.00000000 1.377136 3.051858 1.0227254 - - - P. aerophilum family 1964 protein 1.434811 3.162538 1.0684434 - - - P. aerophilum family 1964 protein 0.000000e+00 0 3.326430e-03 1.231307e-03 2.182964e-02 3.788059e-02 2.994265e-01 0 0 TRUE TRUE -19 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179576 0.5419791 U 0.4686274 0.6162291 13773 129 182269 182270 1 182 Same + + 0.000000 0 0.000000 0.00000000 1.434811 3.162538 1.0684434 - - - P. aerophilum family 1964 protein 1.357337 2.940899 1.0208669 - - - paREP8 0.000000e+00 0 6.002262e-03 1.559609e-03 6.074067e-02 4.570479e-02 4.530127e-01 0 0 TRUE TRUE -18 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185842 0.5032088 U 0.4686274 0.6162291 13773 129 182270 182271 1 44 Convergent + - 0.000000 0 0.000000 0.00000000 1.357337 2.940899 1.0208669 - - - paREP8 1.469060 3.861273 1.1846710 - - - hypothetical protein 0.000000e+00 0 1.248200e-02 -1.661676e-03 -2.036430e-02 -1.912830e-01 9.908117e-01 0 0 TRUE TRUE -17 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4670745 0.4400938 U 0.4686274 0.6162291 13773 129 182271 182272 1 222 Divergent - + 0.000000 0 0.000000 0.00000000 1.469060 3.861273 1.1846710 - - - hypothetical protein 1.714177 3.796050 1.1143946 - - - hypothetical protein 0.000000e+00 0 6.008231e-02 4.642572e-03 2.495940e-01 2.533801e-01 5.094213e-01 0 0 FALSE TRUE -18 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5711958 0.4915849 U 0.4686274 0.6162291 13773 129 182272 182273 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.714177 3.796050 1.1143946 - - - hypothetical protein 1.515251 3.398809 1.1402124 - - - hypothetical protein 0.000000e+00 0 3.957122e-02 1.678102e-02 5.193537e-02 5.792613e-01 1.437358e-01 0 0 TRUE TRUE -17 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7123715 0.5944258 U 0.4686274 0.6162291 13773 129 182273 182274 1 18 Same + + 0.000000 0 0.000000 0.00000000 1.515251 3.398809 1.1402124 - - - hypothetical protein 1.473344 3.441782 1.1343951 - - - hypothetical protein 0.000000e+00 0 1.756271e-03 1.401746e-03 2.799499e-02 1.780236e-01 8.730370e-02 0 0 TRUE TRUE -16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5414952 0.6120657 U 0.4686274 0.6162291 13773 129 182274 182275 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.473344 3.441782 1.1343951 - - - hypothetical protein 1.389650 3.149471 1.0715611 - - - hypothetical protein 0.000000e+00 0 7.004693e-03 -1.355312e-03 1.334857e-02 -1.509180e-01 6.456610e-01 0 0 TRUE TRUE -15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4763942 0.4708055 U 0.4686274 0.6162291 13773 129 182275 182276 1 33 Convergent + - 0.000000 0 0.000000 0.00000000 1.389650 3.149471 1.0715611 - - - hypothetical protein 1.475138 3.759607 1.1642730 - - - hypothetical protein 0.000000e+00 0 7.308334e-03 -1.466126e-03 -4.653963e-03 -1.602053e-01 6.756007e-01 0 0 TRUE TRUE -14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4740776 0.4673400 U 0.4686274 0.6162291 13773 129 182276 182277 1 25 Divergent - + 0.000000 0 0.000000 0.00000000 1.475138 3.759607 1.1642730 - - - hypothetical protein 1.430996 3.253966 1.1196774 - - - paREP1 0.000000e+00 0 1.948507e-03 -4.843226e-04 1.469942e-02 -3.267505e-02 1.768774e-01 0 0 FALSE TRUE -15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5114123 0.5857870 U 0.4686274 0.6162291 13773 129 182277 182278 1 108 Same + + 0.000000 0 0.000000 0.00000000 1.430996 3.253966 1.1196774 - - - paREP1 1.360754 2.963294 1.0318633 - - - hypothetical protein 0.000000e+00 0 4.933982e-03 1.848701e-03 6.215977e-02 7.395296e-02 3.797889e-01 0 0 TRUE TRUE -14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179099 0.5171998 U 0.4686274 0.6162291 13773 129 182278 182279 1 42 Same + + 0.000000 0 0.000000 0.00000000 1.360754 2.963294 1.0318633 - - - hypothetical protein 1.295479 2.835980 0.9116684 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase, putative 0.000000e+00 0 4.260907e-03 1.413187e-02 2.268421e-01 6.865484e-01 5.551213e-02 0 0 TRUE TRUE -13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7487698 0.6218902 U 0.4686274 0.6162291 13773 129 182279 182280 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.295479 2.835980 0.9116684 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase, putative 1.505620 3.164836 1.0672619 5428 Uncharacterized conserved small protein S conserved hypothetical protein 0.000000e+00 0 4.415937e-02 -8.454764e-03 -1.323838e-01 -5.150945e-01 2.232765e+00 0 0 TRUE TRUE -12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4039311 0.4054672 U 0.4686274 0.6162291 13773 129 182280 182281 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.505620 3.164836 1.0672619 5428 Uncharacterized conserved small protein S conserved hypothetical protein 1.374988 3.153171 1.0910002 - - - paREP1 0.000000e+00 0 1.706469e-02 -4.143208e-03 -2.034854e-02 -3.399458e-01 1.367984e+00 0 0 TRUE TRUE -11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4302357 0.4212714 U 0.4686274 0.6162291 13773 129 182281 182282 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.374988 3.153171 1.0910002 - - - paREP1 1.431902 3.094387 1.0542379 - - - P. aerophilum family 1964 protein 0.000000e+00 0 3.239172e-03 1.489223e-03 2.428996e-02 5.802773e-02 2.894324e-01 0 0 TRUE TRUE -10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186413 0.5469760 U 0.4686274 0.6162291 13773 129 182282 182283 1 79 Same + + 0.000000 0 0.000000 0.00000000 1.431902 3.094387 1.0542379 - - - P. aerophilum family 1964 protein 1.479891 3.506110 1.1686165 - - - hypothetical protein 0.000000e+00 0 2.302991e-03 -5.554657e-04 1.534072e-02 -3.357268e-02 2.085187e-01 0 0 TRUE TRUE -9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5110166 0.5767479 U 0.4686274 0.6162291 13773 129 182283 182284 1 245 Same + + 0.000000 0 0.000000 0.00000000 1.479891 3.506110 1.1686165 - - - hypothetical protein 1.664680 3.449679 1.0868861 - - - hypothetical protein 0.000000e+00 0 3.414690e-02 6.078319e-03 2.052704e-01 3.449593e-01 3.384150e-01 0 0 TRUE TRUE -8 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6109214 0.5278884 U 0.4686274 0.6162291 13773 129 182284 182285 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.664680 3.449679 1.0868861 - - - hypothetical protein 1.357276 2.816641 0.9869405 5428 Uncharacterized conserved small protein S conserved hypothetical protein 0.000000e+00 0 9.449745e-02 -2.007400e-02 -3.070038e-01 -6.964547e-01 2.830038e+00 0 1 TRUE TRUE -7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3874750 0.4016632 U 0.4686274 0.6162291 13773 129 182285 182286 1 345 Same + + 0.000000 0 0.000000 -0.11778304 1.357276 2.816641 0.9869405 5428 Uncharacterized conserved small protein S conserved hypothetical protein 1.371554 2.952738 1.0379826 438 Glycosyltransferase M glycosyltransferase (type 1) 2.394346e-02 1 2.038830e-04 7.514182e-03 1.022878e-01 4.784243e-01 7.388346e-03 1 13 TRUE TRUE -6 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.6329203 0.7020387 0.6658667 0.6442479 U 0.4686274 0.5554237 13773 129 182286 182287 1 8 Same + + 0.000000 0 0.000000 0.00000000 1.371554 2.952738 1.0379826 438 Glycosyltransferase M glycosyltransferase (type 1) 1.399566 3.095248 1.0385645 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 7.846408e-04 4.137796e-03 5.975188e-02 2.763786e-01 5.056458e-02 M 13 0 TRUE TRUE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5832948 0.6236602 Y 1.4497162 0.7118045 13773 129 182287 182288 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.399566 3.095248 1.0385645 438 Glycosyltransferase M glycosyltransferase (type 1) 1.323517 3.353834 1.0672037 - - - hypothetical protein 0.000000e+00 0 5.783416e-03 6.627430e-03 1.329329e-01 3.772062e-01 2.134539e-01 0 0 TRUE TRUE -4 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6238451 0.5754016 U 0.4686274 0.6162291 13773 129 182288 182289 1 -37 Divergent - + 0.000000 0 0.000000 0.00000000 1.323517 3.353834 1.0672037 - - - hypothetical protein 1.327074 2.845907 0.9751546 - - - hypothetical protein 0.000000e+00 0 1.265180e-05 1.589738e-02 2.043363e-01 7.789239e-01 8.481519e-05 0 0 FALSE TRUE -5 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7777240 0.6551679 U 0.4686274 0.6162291 13773 129 182289 182290 1 -12 Convergent + - 0.000000 0 0.000000 0.00000000 1.327074 2.845907 0.9751546 - - - hypothetical protein 1.415749 3.428400 1.0697421 - - - hypothetical protein 0.000000e+00 0 7.863179e-03 4.431265e-03 3.652718e-02 2.250524e-01 3.864392e-01 0 0 TRUE TRUE -4 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5596744 0.5147662 U 0.4686274 0.6162291 13773 129 182290 182291 1 -18 Same - - 0.000000 0 0.000000 0.00000000 1.415749 3.428400 1.0697421 - - - hypothetical protein 1.451915 3.729576 1.1204724 - - - hypothetical protein 0.000000e+00 0 1.308032e-03 -1.862011e-05 1.729418e-02 -2.596759e-02 1.279037e-01 0 0 FALSE TRUE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5135970 0.5985607 U 0.4686274 0.6162291 13773 129 182291 182292 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.451915 3.729576 1.1204724 - - - hypothetical protein 1.363728 3.479496 1.1351885 - - - hypothetical protein 0.000000e+00 0 7.777007e-03 -4.579496e-05 3.971804e-02 -7.129424e-02 6.481300e-01 0 0 FALSE TRUE -6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5012661 0.4705979 U 0.4686274 0.6162291 13773 129 182292 182293 1 52 Divergent - + 0.000000 0 0.000000 0.00000000 1.363728 3.479496 1.1351885 - - - hypothetical protein 1.364235 3.158942 1.0515013 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 0.000000e+00 0 2.574256e-07 7.640666e-03 1.098492e-01 4.931185e-01 9.423910e-06 0 0 FALSE TRUE -7 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6700358 0.6557762 U 0.4686274 0.6162291 13773 129 182293 182294 1 72 Same + + 0.000000 0 0.000000 0.00000000 1.364235 3.158942 1.0515013 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 1.420393 3.486424 1.1907116 - - - conserved within P. aerophilum 0.000000e+00 0 3.153694e-03 2.701870e-03 3.547791e-02 1.516460e-01 2.345146e-01 0 0 TRUE TRUE -6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5309326 0.5687032 U 0.4686274 0.6162291 13773 129 182294 182295 1 317 Same + + 0.000000 0 0.000000 0.00000000 1.420393 3.486424 1.1907116 - - - conserved within P. aerophilum 1.497122 3.374596 1.0756764 463 Glycosyltransferases involved in cell wall biogenesis M dolichol-phosphate mannosyltransferase 0.000000e+00 0 5.887343e-03 -1.417597e-03 7.032825e-03 -1.053051e-01 4.941993e-01 0 1 TRUE TRUE -5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4895405 0.4931854 U 0.4686274 0.6162291 13773 129 182295 182296 1 8 Same + + 0.000000 0 0.000000 0.00000000 1.497122 3.374596 1.0756764 463 Glycosyltransferases involved in cell wall biogenesis M dolichol-phosphate mannosyltransferase 1.400555 2.998989 1.0416103 438 Glycosyltransferase M glycosyltransferase (type 1) 6.480885e-03 1 9.325203e-03 -2.324776e-03 -5.191422e-03 -2.012747e-01 8.104145e-01 M 1 28 TRUE TRUE -4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5633858 0.4640987 0.4540804 Y 1.4497162 0.7118045 13773 129 182296 182297 1 -3 Same + + 1.386294 0 1.386294 0.98504867 1.400555 2.998989 1.0416103 438 Glycosyltransferase M glycosyltransferase (type 1) 1.602482 3.541892 1.0325110 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) -2.792919e-02 9 4.077435e-02 -7.681032e-03 -1.766302e-02 -3.596912e-01 1.646583e+00 M 28 9 TRUE TRUE -3 TRUE 2.9315946 1.6381882 0.5480306 2.9462377 0.7702221 0.5246855 0.4261972 0.4134553 Y 1.4497162 0.8866684 13773 129 182297 182298 1 368 Same + + 0.000000 0 0.000000 -0.07232066 1.602482 3.541892 1.0325110 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 1.643890 3.457129 0.9462797 438 Glycosyltransferase M glycosyltransferase (type 1) 1.668113e-02 3 1.714652e-03 2.908413e-02 3.969279e-01 8.061354e-01 3.313094e-03 M 9 3 TRUE TRUE -2 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.7136133 0.6526578 0.7880025 0.6480385 Y 1.4497162 0.6595066 13773 129 182298 182299 1 35 Same + + 0.000000 0 0.000000 -0.05918887 1.643890 3.457129 0.9462797 438 Glycosyltransferase M glycosyltransferase (type 1) 1.662163 3.514107 1.0342301 500 SAM-dependent methyltransferases QR conserved protein 4.578021e-02 1 3.338974e-04 4.057259e-02 5.138370e-01 8.730169e-01 2.126270e-04 3 1 TRUE TRUE -1 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.8313457 0.7998677 0.6544230 U 0.4686274 0.5589164 13773 129 182299 182300 1 -16 Same + + 0.000000 0 0.000000 0.00000000 1.662163 3.514107 1.0342301 500 SAM-dependent methyltransferases QR conserved protein 1.633679 3.765655 1.1710826 - - - hypothetical protein 0.000000e+00 0 8.113325e-04 3.842041e-02 4.415282e-01 8.636219e-01 6.031303e-04 1 0 TRUE TRUE 0 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7974794 0.6529329 U 0.4686274 0.6162291 13773 129 182300 182301 1 52 Same + + 0.000000 0 0.000000 0.00000000 1.633679 3.765655 1.1710826 - - - hypothetical protein 1.515875 3.279334 1.0598322 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 0.000000e+00 0 1.387784e-02 1.175413e-02 8.434602e-02 5.504094e-01 1.004642e-01 0 0 TRUE TRUE 1 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6988730 0.6066151 U 0.4686274 0.6162291 13773 129 182301 182302 1 1137 Convergent + - 0.000000 0 0.000000 0.00000000 1.515875 3.279334 1.0598322 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 1.434136 3.435078 1.1246668 - - - conserved within P. aerophilum, degenerate 0.000000e+00 0 6.681146e-03 -1.112729e-03 -2.075447e-03 -3.915046e-02 4.427406e-01 0 0 TRUE TRUE 2 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5092929 0.5051964 U 0.4686274 0.6162291 13773 129 182302 182303 1 122 Divergent - + 0.000000 0 0.000000 0.00000000 1.434136 3.435078 1.1246668 - - - conserved within P. aerophilum, degenerate 1.337418 3.213385 1.1259724 - - - hypothetical protein 0.000000e+00 0 9.354455e-03 1.966805e-03 7.596683e-02 5.522117e-02 6.103890e-01 0 0 FALSE TRUE 1 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187270 0.4756240 U 0.4686274 0.6162291 13773 129 182303 182304 1 78 Same + + 0.000000 0 0.000000 0.00000000 1.337418 3.213385 1.1259724 - - - hypothetical protein 1.594369 3.506320 1.0689681 - - - hypothetical protein 0.000000e+00 0 6.602375e-02 -1.629567e-02 -1.508718e-01 -7.250215e-01 2.900185e+00 0 0 TRUE TRUE 2 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3855797 0.4011845 U 0.4686274 0.6162291 13773 129 182304 182305 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.594369 3.506320 1.0689681 - - - hypothetical protein 1.469109 3.282375 1.1226169 - - - hypothetical protein 0.000000e+00 0 1.569006e-02 2.532960e-03 -7.621540e-04 2.241454e-01 3.537648e-01 0 0 TRUE TRUE 3 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5587563 0.5241295 U 0.4686274 0.6162291 13773 129 182305 182306 1 817 Same + + 0.000000 0 0.000000 0.00000000 1.469109 3.282375 1.1226169 - - - hypothetical protein 1.521885 3.387503 1.0548577 - - - hypothetical protein 0.000000e+00 0 2.785353e-03 1.248843e-03 4.716175e-02 1.652972e-01 1.368375e-01 0 0 TRUE TRUE 4 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5366428 0.5965788 U 0.4686274 0.6162291 13773 129 182306 182307 1 34 Same + + 0.000000 0 0.000000 0.00000000 1.521885 3.387503 1.0548577 - - - hypothetical protein 1.525716 3.422661 1.1090150 - - - hypothetical protein 0.000000e+00 0 1.467738e-05 5.239247e-03 8.340536e-02 4.120310e-01 4.293769e-04 0 0 TRUE TRUE 5 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6397142 0.6535639 U 0.4686274 0.6162291 13773 129 182307 182308 1 276 Same + + 0.000000 0 0.000000 0.00000000 1.525716 3.422661 1.1090150 - - - hypothetical protein 1.572433 3.270698 1.0780297 - - - hypothetical protein 0.000000e+00 0 2.182485e-03 8.996167e-03 1.491011e-01 5.276801e-01 2.451159e-02 0 0 TRUE TRUE 6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6877943 0.6356211 U 0.4686274 0.6162291 13773 129 182308 182309 1 124 Same + + 0.000000 0 0.000000 0.00000000 1.572433 3.270698 1.0780297 - - - hypothetical protein 1.606786 3.741842 1.1611464 - - - hypothetical protein 0.000000e+00 0 1.180095e-03 1.880888e-02 2.647721e-01 7.089537e-01 4.561173e-03 0 0 TRUE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7563161 0.6466721 U 0.4686274 0.6162291 13773 129 182309 182310 1 476 Convergent + - 0.000000 0 0.000000 0.00000000 1.606786 3.741842 1.1611464 - - - hypothetical protein 1.552959 3.515751 1.0701886 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 2.897392e-03 1.578261e-02 1.701474e-01 6.605242e-01 1.507826e-02 0 0 TRUE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7396012 0.6403514 U 0.4686274 0.6162291 13773 129 182310 182311 1 121 Same - - 0.000000 0 0.000000 0.00000000 1.552959 3.515751 1.0701886 438 Glycosyltransferase M glycosyltransferase (type 1) 1.478478 3.562969 1.1431846 - - - hypothetical protein 0.000000e+00 0 5.547367e-03 2.750912e-03 2.856857e-02 2.666389e-01 1.598772e-01 0 0 FALSE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5762566 0.5899841 U 0.4686274 0.6162291 13773 129 182311 182312 1 141 Same - - 0.000000 0 0.000000 0.00000000 1.478478 3.562969 1.1431846 - - - hypothetical protein 1.341111 3.513901 1.2100912 - - - hypothetical protein 0.000000e+00 0 1.886974e-02 -2.986997e-03 1.483578e-02 -2.924340e-01 1.393233e+00 0 0 FALSE TRUE 6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4423997 0.4200228 U 0.4686274 0.6162291 13773 129 182312 182313 1 -10 Divergent - + 0.000000 0 0.000000 0.00000000 1.341111 3.513901 1.2100912 - - - hypothetical protein 1.537136 3.454660 1.0823815 - - - hypothetical protein 0.000000e+00 0 3.842600e-02 -9.455963e-03 -1.020397e-01 -5.804275e-01 2.337167e+00 0 0 FALSE TRUE 5 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3959084 0.4048015 U 0.4686274 0.6162291 13773 129 182313 182314 1 129 Same + + 0.000000 0 0.000000 0.00000000 1.537136 3.454660 1.0823815 - - - hypothetical protein 1.709547 3.756470 1.1375998 - - - hypothetical protein 0.000000e+00 0 2.972561e-02 2.213504e-02 4.301189e-01 6.822852e-01 7.256470e-02 0 0 TRUE TRUE 6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7474495 0.6171587 U 0.4686274 0.6162291 13773 129 182314 182315 1 118 Same + + 0.000000 0 0.000000 0.00000000 1.709547 3.756470 1.1375998 - - - hypothetical protein 1.629491 3.659627 1.1113919 - - - hypothetical protein 0.000000e+00 0 6.408945e-03 4.597697e-02 4.696219e-01 8.828696e-01 3.960398e-03 0 0 TRUE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8013042 0.6473139 U 0.4686274 0.6162291 13773 129 182315 182316 1 454 Convergent + - 0.000000 0 0.000000 0.00000000 1.629491 3.659627 1.1113919 - - - hypothetical protein 1.424738 3.398583 1.1701283 - - - hypothetical protein 0.000000e+00 0 4.192408e-02 -4.747232e-03 -1.135150e-01 -1.583028e-01 1.172641e+00 0 0 TRUE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4747262 0.4295614 U 0.4686274 0.6162291 13773 129 182316 182317 1 74 Same - - 0.000000 0 0.000000 0.00000000 1.424738 3.398583 1.1701283 - - - hypothetical protein 1.480989 2.998141 1.1184797 - - - hypothetical protein 0.000000e+00 0 3.164162e-03 -7.888784e-04 1.193399e-02 -6.511274e-02 3.002670e-01 0 0 FALSE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5024770 0.5413986 U 0.4686274 0.6162291 13773 129 182317 182318 1 158 Divergent - + 0.000000 0 0.000000 0.00000000 1.480989 2.998141 1.1184797 - - - hypothetical protein 1.547871 3.362495 1.0999044 - - - hypothetical protein 0.000000e+00 0 4.473218e-03 2.855343e-03 7.553650e-02 2.756535e-01 1.323329e-01 0 0 FALSE TRUE 6 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5830549 0.5978214 U 0.4686274 0.6162291 13773 129 182318 182319 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.547871 3.362495 1.0999044 - - - hypothetical protein 1.492861 3.299883 1.1405026 - - - hypothetical protein 0.000000e+00 0 3.026084e-03 4.000755e-03 4.824486e-02 3.362180e-01 7.933107e-02 0 0 TRUE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6076712 0.6149078 U 0.4686274 0.6162291 13773 129 182319 182320 1 307 Convergent + - 0.000000 0 0.000000 0.00000000 1.492861 3.299883 1.1405026 - - - hypothetical protein 1.710299 3.924378 1.1990936 - - - hypothetical protein 0.000000e+00 0 4.727943e-02 1.073635e-02 3.121329e-01 4.432760e-01 2.667726e-01 0 0 TRUE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6527700 0.5549894 U 0.4686274 0.6162291 13773 129 182320 182321 1 391 Same - - 0.000000 0 0.000000 0.00000000 1.710299 3.924378 1.1990936 - - - hypothetical protein 1.433977 3.103026 1.0073698 - - - paREP15, putative coiled-coil protein 0.000000e+00 0 7.635422e-02 -4.509179e-03 -2.014443e-01 -6.492426e-02 1.079813e+00 0 0 FALSE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5025560 0.4343694 U 0.4686274 0.6162291 13773 129 182321 182322 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.433977 3.103026 1.0073698 - - - paREP15, putative coiled-coil protein 1.791851 4.059936 1.1704599 - - - hypothetical protein 0.000000e+00 0 1.280742e-01 -5.929508e-03 2.449972e-01 -6.610284e-02 1.116809e+00 0 0 FALSE TRUE 6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5021988 0.4319393 U 0.4686274 0.6162291 13773 129 182322 182323 1 743 Divergent - + 0.000000 0 0.000000 0.00000000 1.791851 4.059936 1.1704599 - - - hypothetical protein 1.319622 2.943672 1.1463830 - - - hypothetical protein 0.000000e+00 0 2.230003e-01 -4.486246e-02 -7.540712e-01 -8.889693e-01 3.564359e+00 0 0 FALSE TRUE 5 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3796149 0.3994755 U 0.4686274 0.6162291 13773 129 182323 182324 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.319622 2.943672 1.1463830 - - - hypothetical protein 1.261941 2.891263 1.0247312 - - - paREP8 0.000000e+00 0 3.327050e-03 2.496415e-02 3.596783e-01 8.813889e-01 6.997843e-03 0 0 TRUE TRUE 6 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8008250 0.6444474 U 0.4686274 0.6162291 13773 129 182324 182325 1 540 Same + + 0.000000 0 0.000000 0.00000000 1.261941 2.891263 1.0247312 - - - paREP8 1.861645 4.477788 1.1808619 - - - hypothetical protein 0.000000e+00 0 3.596443e-01 -7.772282e-02 -5.517503e-01 -9.785677e-01 3.914506e+00 0 0 TRUE TRUE 7 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3774536 0.3988586 U 0.4686274 0.6162291 13773 129 182325 182326 1 348 Convergent + - 0.000000 0 0.000000 0.00000000 1.861645 4.477788 1.1808619 - - - hypothetical protein 1.423929 3.296565 1.1368809 - - - paREP1 0.000000e+00 0 1.915957e-01 -1.126728e-02 -5.365037e-01 -1.843900e-01 1.396859e+00 0 0 TRUE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4688720 0.4197398 U 0.4686274 0.6162291 13773 129 182326 182327 1 57 Divergent - + 0.000000 0 0.000000 0.00000000 1.423929 3.296565 1.1368809 - - - paREP1 1.428213 3.288383 1.0756787 - - - hypothetical protein 0.000000e+00 0 1.835558e-05 6.366210e-04 2.763023e-02 2.555058e-02 2.191648e-03 0 0 FALSE TRUE 7 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173896 0.6499017 U 0.4686274 0.6162291 13773 129 182327 182328 1 210 Same + + 0.000000 0 0.000000 0.00000000 1.428213 3.288383 1.0756787 - - - hypothetical protein 1.481035 3.166317 1.0053279 - - - paREP15, putative coiled-coil protein 0.000000e+00 0 2.790211e-03 -6.871117e-04 1.357069e-02 -5.173727e-02 2.628234e-01 0 0 TRUE TRUE 8 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5062794 0.5561071 U 0.4686274 0.6162291 13773 129 182328 182329 1 1138 Same + + 0.000000 0 0.000000 0.00000000 1.481035 3.166317 1.0053279 - - - paREP15, putative coiled-coil protein 1.818289 4.447277 1.1822313 - - - hypothetical protein 0.000000e+00 0 1.137402e-01 1.087573e-02 4.875192e-01 3.722209e-01 3.835820e-01 0 0 TRUE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6215428 0.5159995 U 0.4686274 0.6162291 13773 129 182329 182330 1 362 Same + + 0.000000 0 0.000000 0.00000000 1.818289 4.447277 1.1822313 - - - hypothetical protein 1.396272 3.124271 1.0483706 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 0.000000e+00 0 1.780990e-01 -2.022382e-02 -5.498599e-01 -4.523094e-01 2.099496e+00 0 1 TRUE TRUE 10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4115247 0.4071019 U 0.4686274 0.6162291 13773 129 182330 182331 1 156 Same + + 0.000000 0 0.000000 0.00000000 1.396272 3.124271 1.0483706 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 1.452165 3.109320 1.0670261 - - - hypothetical protein 0.000000e+00 0 3.124040e-03 -4.254091e-05 1.252585e-02 -4.750122e-02 3.130158e-01 1 0 TRUE TRUE 11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5071193 0.5374716 U 0.4686274 0.6162291 13773 129 182331 182332 1 136 Same + + 0.000000 0 0.000000 0.00000000 1.452165 3.109320 1.0670261 - - - hypothetical protein 1.654814 4.336860 1.1973675 - - - hypothetical protein 0.000000e+00 0 4.106676e-02 1.569940e-04 1.276571e-01 9.764585e-02 6.908251e-01 0 0 TRUE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183277 0.4655660 U 0.4686274 0.6162291 13773 129 182332 182333 1 1535 Same + + 0.000000 0 0.000000 0.00000000 1.654814 4.336860 1.1973675 - - - hypothetical protein 1.586230 3.559065 1.1245205 - - - conserved within P. aerophilum 0.000000e+00 0 4.703813e-03 2.742864e-02 2.825265e-01 7.854747e-01 9.203038e-03 0 0 TRUE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7800462 0.6433585 U 0.4686274 0.6162291 13773 129 182333 182334 1 312 Same + + 0.000000 0 0.000000 0.00000000 1.586230 3.559065 1.1245205 - - - conserved within P. aerophilum 1.484243 3.057264 1.0117106 - - - paREP15, putative coiled-coil protein 0.000000e+00 0 1.040117e-02 4.429476e-03 2.909822e-02 3.376446e-01 1.913643e-01 0 0 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6079402 0.5826327 U 0.4686274 0.6162291 13773 129 182334 182335 1 914 Same + + 0.000000 0 0.000000 0.00000000 1.484243 3.057264 1.0117106 - - - paREP15, putative coiled-coil protein 1.524529 3.372280 1.0467910 - - - hypothetical protein 0.000000e+00 0 1.622933e-03 2.402575e-03 5.967234e-02 2.592518e-01 5.881463e-02 0 0 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5733592 0.6209502 U 0.4686274 0.6162291 13773 129 182335 182336 1 333 Same + + 0.000000 0 0.000000 0.00000000 1.524529 3.372280 1.0467910 - - - hypothetical protein 1.482996 3.558958 1.1696972 - - - hypothetical protein 0.000000e+00 0 1.725000e-03 2.311339e-03 3.671525e-02 2.513357e-01 6.492132e-02 0 0 TRUE TRUE 16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5695047 0.6191240 U 0.4686274 0.6162291 13773 129 182336 182337 1 362 Convergent + - 0.000000 0 0.000000 0.00000000 1.482996 3.558958 1.1696972 - - - hypothetical protein 1.403828 3.238000 1.0917911 - - - hypothetical protein 0.000000e+00 0 6.267551e-03 -1.503195e-03 6.370931e-03 -1.475101e-01 5.901730e-01 0 0 TRUE TRUE 17 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4775341 0.4780286 U 0.4686274 0.6162291 13773 129 182337 182338 1 123 Same - - 0.000000 0 0.000000 0.00000000 1.403828 3.238000 1.0917911 - - - hypothetical protein 1.463087 3.241807 1.1117737 - - - hypothetical protein 0.000000e+00 0 3.511578e-03 -5.562158e-04 8.836145e-03 -7.927217e-02 3.455960e-01 0 0 FALSE TRUE 16 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4981380 0.5257766 U 0.4686274 0.6162291 13773 129 182338 182339 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.463087 3.241807 1.1117737 - - - hypothetical protein 1.607058 3.610275 1.1453743 - - - hypothetical protein 0.000000e+00 0 2.072764e-02 1.820326e-03 1.032104e-01 1.841108e-01 4.478619e-01 0 0 FALSE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5435713 0.5041686 U 0.4686274 0.6162291 13773 129 182339 182340 1 52 Same - - 0.000000 0 0.000000 0.00000000 1.607058 3.610275 1.1453743 - - - hypothetical protein 1.442568 3.108607 1.0680628 - - - P. aerophilum family 1964 protein 0.000000e+00 0 2.705694e-02 -1.373755e-03 -5.666310e-02 1.281357e-02 7.467719e-01 0 0 FALSE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184664 0.4598829 U 0.4686274 0.6162291 13773 129 182340 182341 1 630 Same - - 0.000000 0 0.000000 0.00000000 1.442568 3.108607 1.0680628 - - - P. aerophilum family 1964 protein 1.327670 2.866640 0.9981864 2062 Phosphohistidine phosphatase SixA T conserved hypothetical protein 0.000000e+00 0 1.320151e-02 1.091865e-03 7.217946e-02 -1.276881e-02 7.925509e-01 0 2 FALSE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174373 0.4565008 U 0.4686274 0.6162291 13773 129 182341 182342 1 451 Divergent - + 0.000000 0 0.000000 0.00000000 1.327670 2.866640 0.9981864 2062 Phosphohistidine phosphatase SixA T conserved hypothetical protein 1.531416 3.246920 1.0047362 - - - paREP15, putative coiled-coil protein 0.000000e+00 0 4.151234e-02 -9.900663e-03 -1.176346e-01 -6.008061e-01 2.439158e+00 2 0 FALSE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3940489 0.4037939 U 0.4686274 0.6162291 13773 129 182342 182343 1 552 Convergent + - 0.000000 0 0.000000 0.00000000 1.531416 3.246920 1.0047362 - - - paREP15, putative coiled-coil protein 1.324435 3.016118 1.0444235 - - - paREP1 0.000000e+00 0 4.284123e-02 -1.015957e-02 -7.338017e-02 -6.065983e-01 2.465599e+00 0 1 TRUE TRUE 13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3931159 0.4036556 U 0.4686274 0.6162291 13773 129 182343 182344 1 731 Divergent - + 0.000000 0 0.000000 0.00000000 1.324435 3.016118 1.0444235 - - - paREP1 1.526026 3.258813 1.0800914 5550 Predicted aspartyl protease O conserved within P. aerophilum 0.000000e+00 0 4.063903e-02 -9.475271e-03 -1.168375e-01 -5.787789e-01 2.367772e+00 1 0 FALSE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3961402 0.4042444 U 0.4686274 0.6162291 13773 129 182344 182345 1 17 Convergent + - 0.000000 0 0.000000 0.00000000 1.526026 3.258813 1.0800914 5550 Predicted aspartyl protease O conserved within P. aerophilum 1.691996 3.954591 1.1726342 - - - hypothetical protein 0.000000e+00 0 2.754620e-02 1.795694e-02 3.635621e-01 6.330394e-01 9.756633e-02 0 0 TRUE TRUE 13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7310330 0.6075710 U 0.4686274 0.6162291 13773 129 182345 182346 1 -6 Same - - 0.000000 0 0.000000 0.00000000 1.691996 3.954591 1.1726342 - - - hypothetical protein 1.724784 3.698313 1.0783062 - - - P. aerophilum family 1964 protein, degenerate 0.000000e+00 0 1.075028e-03 6.577881e-02 8.326394e-01 9.462195e-01 1.325237e-04 0 0 FALSE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8109474 0.6548417 U 0.4686274 0.6162291 13773 129 182346 182347 1 152 Divergent - + 0.000000 0 0.000000 0.00000000 1.724784 3.698313 1.0783062 - - - P. aerophilum family 1964 protein, degenerate 1.468102 3.469237 1.1561796 - - - hypothetical protein 0.000000e+00 0 6.588580e-02 4.568017e-03 -1.149524e-01 2.433136e-01 5.326871e-01 0 0 FALSE TRUE 11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5666272 0.4869405 U 0.4686274 0.6162291 13773 129 182347 182348 1 138 Same + + 0.000000 0 0.000000 0.00000000 1.468102 3.469237 1.1561796 - - - hypothetical protein 1.402819 3.161144 1.1237955 - - - conserved within P. aerophilum 0.000000e+00 0 4.261756e-03 -8.115998e-04 1.653091e-02 -9.675293e-02 4.067366e-01 0 0 TRUE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4931567 0.5111403 U 0.4686274 0.6162291 13773 129 182348 182349 1 242 Convergent + - 0.000000 0 0.000000 0.00000000 1.402819 3.161144 1.1237955 - - - conserved within P. aerophilum 1.578979 3.835558 1.1871667 - - - hypothetical protein 0.000000e+00 0 3.103214e-02 -6.197287e-03 -1.637576e-02 -3.201208e-01 1.468505e+00 0 0 TRUE TRUE 13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4355148 0.4178096 U 0.4686274 0.6162291 13773 129 182349 182350 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.578979 3.835558 1.1871667 - - - hypothetical protein 1.663793 3.630068 1.0717755 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 7.193455e-03 2.709931e-02 4.108189e-01 7.766245e-01 1.470366e-02 0 0 FALSE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7763347 0.6405191 U 0.4686274 0.6162291 13773 129 182350 182351 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.663793 3.630068 1.0717755 438 Glycosyltransferase M glycosyltransferase (type 1) 1.582537 3.456512 1.0611029 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 6.602531e-03 2.785509e-02 2.755367e-01 7.860425e-01 1.238361e-02 M 0 1 TRUE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7805116 0.6418162 Y 1.4497162 0.7118045 13773 129 182351 182352 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.582537 3.456512 1.0611029 438 Glycosyltransferase M glycosyltransferase (type 1) 1.601972 3.591814 1.0780973 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 3.777271e-04 1.974765e-02 2.655374e-01 7.227756e-01 1.246312e-03 M 1 0 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7612563 0.6515199 Y 1.4497162 0.7118045 13773 129 182352 182353 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.601972 3.591814 1.0780973 438 Glycosyltransferase M glycosyltransferase (type 1) 1.630283 3.519767 1.0214138 438 Glycosyltransferase M glycosyltransferase (type 1) 0.000000e+00 0 8.015111e-04 2.693724e-02 3.593830e-01 7.920555e-01 1.981377e-03 M 0 0 TRUE TRUE 15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7819098 0.6503033 Y 1.4497162 0.7118045 13773 129 182353 182354 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.630283 3.519767 1.0214138 438 Glycosyltransferase M glycosyltransferase (type 1) 1.705953 3.744206 1.0619546 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 0.000000e+00 0 5.725892e-03 4.553838e-02 6.364787e-01 8.844970e-01 3.225333e-03 M 0 1 FALSE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8017836 0.6482245 Y 1.4497162 0.7118045 13773 129 182354 182355 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.705953 3.744206 1.0619546 463 Glycosyltransferases involved in cell wall biogenesis M glycosyltransferase (type 2) 1.744695 3.714975 0.9010390 - - - hypothetical protein 0.000000e+00 0 1.500925e-03 7.466296e-02 9.476193e-01 9.536797e-01 2.126270e-04 1 0 FALSE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8114326 0.6544230 U 0.4686274 0.6162291 13773 129 182355 182356 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.744695 3.714975 0.9010390 - - - hypothetical protein 1.340482 2.883721 0.9630349 1232 Protoporphyrinogen oxidase H conserved hypothetical protein 0.000000e+00 0 1.633876e-01 -3.253023e-02 -5.468398e-01 -8.170083e-01 3.291593e+00 0 6 FALSE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3817691 0.4000228 U 0.4686274 0.6162291 13773 129 182356 182357 1 128 Same - - 0.000000 0 0.000000 0.00000000 1.340482 2.883721 0.9630349 1232 Protoporphyrinogen oxidase H conserved hypothetical protein 1.445917 3.114719 1.0011649 - - - paREP7 0.000000e+00 0 1.111650e-02 6.072987e-04 -3.324261e-03 -3.313918e-02 7.574209e-01 6 0 FALSE TRUE 11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5113463 0.4587978 U 0.4686274 0.6162291 13773 129 182357 182358 1 627 Divergent - + 0.000000 0 0.000000 0.00000000 1.445917 3.114719 1.0011649 - - - paREP7 1.488572 3.377628 1.1161137 - - - paREP7 0.000000e+00 0 1.819428e-03 -2.035776e-04 2.179161e-02 1.724340e-02 1.537988e-01 0 0 FALSE TRUE 10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178710 0.5921731 U 0.4686274 0.6162291 13773 129 182358 182359 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.488572 3.377628 1.1161137 - - - paREP7 1.484665 3.402347 1.2067307 - - - hypothetical protein 0.000000e+00 0 1.526649e-05 1.237023e-03 3.450227e-02 1.750868e-01 7.215181e-04 0 0 TRUE TRUE 11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5403307 0.6523872 U 0.4686274 0.6162291 13773 129 182359 182360 1 8 Same + + 0.000000 0 0.000000 0.00000000 1.484665 3.402347 1.2067307 - - - hypothetical protein 1.443478 2.827233 0.9997025 - - - conserved hypothetical protein 0.000000e+00 0 1.696315e-03 -2.633274e-04 1.500657e-02 8.085715e-03 1.484289e-01 0 0 TRUE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191105 0.5935741 U 0.4686274 0.6162291 13773 129 182360 182361 1 635 Same + + 0.000000 0 0.000000 0.00000000 1.443478 2.827233 0.9997025 - - - conserved hypothetical protein 1.523044 3.582634 1.1300851 - - - hypothetical protein 0.000000e+00 0 6.330719e-03 -5.670779e-04 2.698584e-02 1.272581e-02 3.816831e-01 0 0 TRUE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185310 0.5164229 U 0.4686274 0.6162291 13773 129 182361 182362 1 45 Same + + 0.000000 0 0.000000 0.00000000 1.523044 3.582634 1.1300851 - - - hypothetical protein 1.524731 3.661744 1.2089984 531 Amino acid transporters E amino acid permease 0.000000e+00 0 2.845818e-06 5.254798e-03 8.279940e-02 4.121206e-01 7.126832e-05 0 28 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6400243 0.6552829 U 0.4686274 0.6162291 13773 129 182362 182363 1 711 Same + + 0.000000 0 0.000000 0.00000000 1.524731 3.661744 1.2089984 531 Amino acid transporters E amino acid permease 1.465874 3.318462 1.0156462 - - - conserved within P. aerophilum 0.000000e+00 0 3.464145e-03 1.062041e-03 2.002914e-02 1.467963e-01 1.755887e-01 28 0 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5296058 0.5861247 U 0.4686274 0.6162291 13773 129 182363 182364 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.465874 3.318462 1.0156462 - - - conserved within P. aerophilum 1.352662 3.015860 1.0642431 - - - hypothetical protein 0.000000e+00 0 1.281706e-02 -1.429762e-03 2.824263e-02 -1.732963e-01 9.801456e-01 0 0 TRUE TRUE 16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4721070 0.4412509 U 0.4686274 0.6162291 13773 129 182364 182365 1 450 Same - - 0.000000 0 0.000000 0.00000000 1.352662 3.015860 1.0642431 - - - hypothetical protein 1.387849 2.950364 0.9935059 - - - paREP8 0.000000e+00 0 1.238122e-03 6.273775e-03 7.959191e-02 3.963567e-01 5.918746e-02 0 0 FALSE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6323925 0.6207976 U 0.4686274 0.6162291 13773 129 182365 182366 1 47 Same - - 0.000000 0 0.000000 0.00000000 1.387849 2.950364 0.9935059 - - - paREP8 1.290822 2.829749 0.9741649 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR ADP ribose hydrolase, putative (mutT/nudix family protein) 0.000000e+00 0 9.414239e-03 1.020334e-02 1.952602e-01 4.992340e-01 1.947363e-01 0 20 FALSE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6724988 0.5814495 U 0.4686274 0.6162291 13773 129 182366 182367 1 484 Divergent - + 0.000000 0 0.000000 -0.13353139 1.290822 2.829749 0.9741649 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR ADP ribose hydrolase, putative (mutT/nudix family protein) 1.397376 3.210011 1.1073654 803 ABC-type metal ion transport system, periplasmic component/surface adhesin P conserved hypothetical protein 1.793207e-02 1 1.135373e-02 8.673605e-03 6.408549e-02 4.321287e-01 2.612520e-01 20 1 FALSE TRUE 13 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.6618908 0.6485535 0.5572152 U 0.4686274 0.5517368 13773 129 182367 182368 1 53 Same + + 0.000000 0 0.000000 0.00000000 1.397376 3.210011 1.1073654 803 ABC-type metal ion transport system, periplasmic component/surface adhesin P conserved hypothetical protein 1.512789 3.551488 1.1537967 530 Ca2+/Na+ antiporter P conserved within P. aerophilum 0.000000e+00 0 1.332024e-02 -3.316448e-03 -1.587645e-02 -2.612791e-01 1.062339e+00 P 1 0 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4496862 0.4351902 Y 1.4497162 0.7118045 13773 129 182368 182369 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.512789 3.551488 1.1537967 530 Ca2+/Na+ antiporter P conserved within P. aerophilum 1.338363 3.062940 1.0026084 5625 Predicted transcription regulator containing HTH domain K conserved hypothetical protein 0.000000e+00 0 3.042429e-02 -6.939571e-03 -3.753045e-02 -4.886722e-01 2.022376e+00 0 0 0 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4068595 0.4078248 N 0.5492530 0.6245624 13773 129 182369 182370 1 -91 Convergent + - 0.000000 0 0.000000 0.00000000 1.338363 3.062940 1.0026084 5625 Predicted transcription regulator containing HTH domain K conserved hypothetical protein 1.430461 3.320145 1.1277458 53 Predicted Co/Zn/Cd cation transporters P cation efflux system protein, conjectural 0.000000e+00 0 8.481885e-03 2.365969e-03 1.707007e-02 9.231191e-02 5.349300e-01 0 0 40 TRUE TRUE 16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178943 0.4860301 N 0.5492530 0.6245624 13773 129 182370 182371 1 2 Same - - 0.000000 0 0.000000 -4.29371737 1.430461 3.320145 1.1277458 53 Predicted Co/Zn/Cd cation transporters P cation efflux system protein, conjectural 1.401303 3.083650 1.0788287 134 Indole-3-glycerol phosphate synthase E indole-3-glycerol-phosphate synthase 1.633962e-02 40 8.501452e-04 1.048491e-03 3.825576e-02 4.447143e-02 8.730370e-02 0 40 42 FALSE TRUE 15 TRUE 0.4469764 0.1835790 0.5480306 0.4469764 0.7733221 0.6505143 0.5185028 0.6120657 N 0.5492530 0.5291282 13773 129 182371 182372 1 54 Divergent - + 0.000000 0 0.000000 -0.29701340 1.401303 3.083650 1.0788287 134 Indole-3-glycerol phosphate synthase E indole-3-glycerol-phosphate synthase 1.365641 3.252753 1.1495084 1738 Uncharacterized conserved protein S conserved hypothetical protein 1.559339e-02 2 1.271786e-03 4.295264e-03 8.326148e-02 2.798901e-01 8.150740e-02 42 2 FALSE TRUE 14 FALSE 0.4469764 0.2556277 0.5480306 0.4469764 0.6838149 0.6420495 0.5842571 0.6138313 U 0.4686274 0.5431568 13773 129 182372 182373 1 -10 Convergent + - 0.000000 0 0.000000 -0.12516314 1.365641 3.252753 1.1495084 1738 Uncharacterized conserved protein S conserved hypothetical protein 1.428979 3.508798 1.1857602 1968 Uncharacterized bacitracin resistance protein V bacitracin resistence protein 1.633075e-04 2 4.011685e-03 1.922021e-03 2.581240e-02 8.799576e-02 3.173243e-01 2 33 TRUE TRUE 15 FALSE 0.4469764 0.2919799 0.5480306 0.4469764 0.6838149 0.4411893 0.5177244 0.5362123 U 0.4686274 0.5546248 13773 129 182373 182374 1 40 Divergent - + 0.000000 0 0.000000 0.00000000 1.428979 3.508798 1.1857602 1968 Uncharacterized bacitracin resistance protein V bacitracin resistence protein 1.408607 3.101819 1.0807917 - - - hypothetical protein 0.000000e+00 0 4.150100e-04 9.589881e-04 3.532350e-02 4.155356e-02 3.951033e-02 33 0 FALSE TRUE 14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183158 0.6282866 U 0.4686274 0.6162291 13773 129 182374 182375 1 234 Same + + 0.000000 0 0.000000 0.00000000 1.408607 3.101819 1.0807917 - - - hypothetical protein 1.402752 3.027119 1.0534508 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 0.000000e+00 0 3.428851e-05 2.081144e-03 4.643057e-02 1.276645e-01 4.255485e-03 0 29 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5237362 0.6470653 U 0.4686274 0.6162291 13773 129 182375 182376 1 -22 Same + + 0.000000 0 0.000000 -3.70119159 1.402752 3.027119 1.0534508 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 1.417603 3.190579 1.0968971 181 Porphobilinogen deaminase H porphobilinogen deaminase (hemC) 1.034651e-02 29 2.205674e-04 1.643574e-03 3.684589e-02 9.372079e-02 2.309094e-02 29 50 TRUE TRUE 16 TRUE 0.4469764 0.1858641 0.5480306 0.4469764 0.7756873 0.6032469 0.5179600 0.6362005 U 0.4686274 0.5210302 13773 129 182376 182377 1 4 Convergent + - 0.000000 0 0.000000 -0.38282396 1.417603 3.190579 1.0968971 181 Porphobilinogen deaminase H porphobilinogen deaminase (hemC) 1.432487 3.086492 1.0490135 1522 Transcriptional regulators K heme biosynthesis protein 2.768716e-03 5 2.215289e-04 6.388244e-04 2.621523e-02 2.039805e-02 2.379596e-02 0 50 5 TRUE TRUE 17 FALSE 0.4469764 0.2444483 0.5480306 0.4469764 0.7448207 0.5102443 0.5176370 0.6358881 N 0.5492530 0.5483979 13773 129 182377 182378 1 464 Same - - 0.000000 0 0.000000 -0.46286667 1.432487 3.086492 1.0490135 1522 Transcriptional regulators K heme biosynthesis protein 1.348758 2.882660 1.0122350 113 Delta-aminolevulinic acid dehydratase H porphobilinogen synthase (delta-aminolevulinic acid dehydratase) (hemB) 2.218276e-02 5 7.010597e-03 1.940408e-03 6.926892e-02 6.701284e-02 4.920436e-01 0 5 54 FALSE TRUE 16 TRUE 0.4469764 0.2366743 0.5480306 0.4469764 0.7448207 0.6931435 0.5181903 0.4938708 N 0.5492530 0.5459437 13773 129 182378 182379 1 -3 Same - - 4.965173 0 4.965173 4.40370356 1.348758 2.882660 1.0122350 113 Delta-aminolevulinic acid dehydratase H porphobilinogen synthase (delta-aminolevulinic acid dehydratase) (hemB) 1.428222 3.138849 1.0549033 1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) H siroheme synthesis protein, conjectural 3.159743e-02 7 6.314527e-03 2.378179e-03 2.315635e-02 1.074620e-01 4.225499e-01 H 54 7 FALSE TRUE 15 TRUE 2.8309038 1.7539654 0.5480306 2.8934512 0.7596462 0.7463571 0.5195988 0.5083822 Y 1.4497162 0.9017791 13773 129 182379 182380 1 28 Same - - 0.000000 0 0.000000 0.00000000 1.428222 3.138849 1.0549033 1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) H siroheme synthesis protein, conjectural 1.404118 3.429374 1.1115850 - - - conserved within P. aerophilum 0.000000e+00 0 5.810093e-04 1.095425e-03 3.785793e-02 5.121483e-02 5.678510e-02 7 0 FALSE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187861 0.6215275 U 0.4686274 0.6162291 13773 129 182380 182381 1 41 Same - - 0.000000 0 0.000000 0.00000000 1.404118 3.429374 1.1115850 - - - conserved within P. aerophilum 1.549005 3.440933 1.1578060 1587 Uroporphyrinogen-III synthase H hypothetical protein 0.000000e+00 0 2.099246e-02 -4.614659e-03 -1.469697e-02 -2.770780e-01 1.240924e+00 0 1 FALSE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4457664 0.4264809 U 0.4686274 0.6162291 13773 129 182381 182382 1 -18 Same - - 0.000000 0 0.000000 -0.11778304 1.549005 3.440933 1.1578060 1587 Uroporphyrinogen-III synthase H hypothetical protein 1.422070 3.201415 1.0944865 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 1.378638e-02 1 1.611249e-02 -2.862247e-03 -3.474192e-02 -1.514428e-01 8.910896e-01 H 1 27 FALSE TRUE 12 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.6329203 0.6306941 0.4761393 0.4474444 Y 1.4497162 0.6577314 13773 129 182382 182383 1 186 Divergent - + 4.762174 0 4.762174 2.33615035 1.422070 3.201415 1.0944865 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 1.431006 3.062010 1.0561681 1 Glutamate-1-semialdehyde aminotransferase H glutamate-1-semialdehyde aminotransferase (hemL) 8.676326e-02 27 7.984495e-05 5.977982e-04 2.659930e-02 2.091578e-02 1.057598e-02 H 27 51 FALSE TRUE 11 FALSE 2.8442642 1.6811206 0.5480306 2.8973705 0.7761702 0.9607049 0.5176105 0.6424418 Y 1.4497162 0.8930882 13773 129 182383 182384 1 4 Same + + 2.512306 0 2.512306 1.53622726 1.431006 3.062010 1.0561681 1 Glutamate-1-semialdehyde aminotransferase H glutamate-1-semialdehyde aminotransferase (hemL) 1.360931 3.005505 1.0628543 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 1.032030e-02 12 4.910489e-03 1.844243e-03 6.202728e-02 7.324440e-02 3.788436e-01 51 12 TRUE TRUE 12 TRUE 2.9301853 1.6437389 0.5480306 2.9452541 0.7776747 0.6023048 0.5179544 0.5175511 U 0.4686274 0.8366907 13773 129 182384 182385 1 356 Same + + 0.000000 0 0.000000 0.00000000 1.360931 3.005505 1.0628543 535 Predicted Fe-S oxidoreductases R metallo cofactor biosynthesis protein 1.430439 2.811607 0.9847340 3809 Uncharacterized protein conserved in bacteria S conserved within P. aerophilum 2.408805e-03 1 4.831315e-03 1.895554e-03 2.323441e-02 7.930221e-02 3.685226e-01 12 1 TRUE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5034409 0.5177783 0.5189918 U 0.4686274 0.6162291 13773 129 182385 182386 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.430439 2.811607 0.9847340 3809 Uncharacterized protein conserved in bacteria S conserved within P. aerophilum 1.498054 3.210510 1.0696583 - - - hypothetical protein 0.000000e+00 0 4.571830e-03 -9.777459e-04 1.371974e-02 -5.487543e-02 3.685226e-01 1 0 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5052768 0.5189918 U 0.4686274 0.6162291 13773 129 182386 182387 1 254 Same + + 0.000000 0 0.000000 0.00000000 1.498054 3.210510 1.0696583 - - - hypothetical protein 1.404375 3.340411 1.1193302 428 Predicted divalent heavy-metal cations transporter P conserved hypothetical protein 0.000000e+00 0 8.775756e-03 -2.193907e-03 -4.829217e-03 -1.840613e-01 7.520870e-01 0 2 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4691457 0.4594361 U 0.4686274 0.6162291 13773 129 182387 182388 1 -23 Convergent + - 0.000000 0 0.000000 0.00000000 1.404375 3.340411 1.1193302 428 Predicted divalent heavy-metal cations transporter P conserved hypothetical protein 1.483297 3.294665 1.1505697 373 Glutamyl-tRNA reductase H glutamyl tRNA reductase (hemA) 2.318180e-03 2 6.228703e-03 -1.500070e-03 1.693223e-04 -1.453715e-01 5.819477e-01 0 2 6 TRUE TRUE 16 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5012279 0.4785376 0.4794292 N 0.5492530 0.6245624 13773 129 182388 182389 1 128 Same - - 0.000000 0 0.000000 0.00000000 1.483297 3.294665 1.1505697 373 Glutamyl-tRNA reductase H glutamyl tRNA reductase (hemA) 1.401513 3.213102 1.2136237 - - - hypothetical protein 0.000000e+00 0 6.688581e-03 -1.591368e-03 5.864261e-03 -1.580125e-01 6.321653e-01 6 0 FALSE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4748554 0.4727649 U 0.4686274 0.6162291 13773 129 182389 182390 1 343 Divergent - + 0.000000 0 0.000000 0.00000000 1.401513 3.213102 1.2136237 - - - hypothetical protein 1.491610 3.171612 1.1014862 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved hypothetical protein 0.000000e+00 0 8.117422e-03 -2.006016e-03 -4.927947e-03 -1.824410e-01 7.322526e-01 0 9 FALSE TRUE 14 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4694186 0.4614144 U 0.4686274 0.6162291 13773 129 182390 182391 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.491610 3.171612 1.1014862 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved hypothetical protein 1.528448 3.218938 1.0943457 1141 Ferredoxin C conserved within P. aerophilum 0.000000e+00 0 1.357067e-03 3.098965e-03 6.794270e-02 3.037209e-01 4.750593e-02 9 0 TRUE TRUE 15 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5933690 0.6249782 U 0.4686274 0.6162291 13773 129 182391 182392 1 47 Same - - 0.000000 0 0.000000 0.00000000 1.528448 3.218938 1.0943457 1141 Ferredoxin C conserved within P. aerophilum 1.378206 3.077149 1.0665030 656 Aldo/keto reductases, related to diketogulonate reductase R oxidoreductase, conjectural 0.000000e+00 0 2.257278e-02 -5.639453e-03 -4.667650e-02 -4.004997e-01 1.607427e+00 0 0 FALSE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4191020 0.4145245 U 0.4686274 0.6162291 13773 129 182392 182393 1 40 Same - - 0.000000 0 0.000000 0.00000000 1.378206 3.077149 1.0665030 656 Aldo/keto reductases, related to diketogulonate reductase R oxidoreductase, conjectural 1.371067 2.930141 1.0227925 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved hypothetical protein 0.000000e+00 0 5.096682e-05 5.878792e-03 9.225733e-02 3.904185e-01 3.225333e-03 0 6 FALSE TRUE 13 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6302998 0.6482245 U 0.4686274 0.6162291 13773 129 182393 182394 1 368 Divergent - + 0.000000 0 0.000000 0.00000000 1.371067 2.930141 1.0227925 1759 ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) R conserved hypothetical protein 1.416649 2.961109 1.0071993 - - - hypothetical protein 0.000000e+00 0 2.077722e-03 2.790830e-03 4.004884e-02 1.625907e-01 1.642022e-01 6 0 FALSE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5353966 0.5889325 U 0.4686274 0.6162291 13773 129 182394 182395 1 81 Convergent + - 0.000000 0 0.000000 0.00000000 1.416649 2.961109 1.0071993 - - - hypothetical protein 1.372332 3.195823 1.1053740 - - - conserved within P. aerophilum 0.000000e+00 0 1.963956e-03 2.746862e-03 6.566255e-02 1.595374e-01 1.544013e-01 0 0 TRUE TRUE 13 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5344367 0.5918248 U 0.4686274 0.6162291 13773 129 182395 182396 1 -24 Same - - 0.000000 0 0.000000 0.00000000 1.372332 3.195823 1.1053740 - - - conserved within P. aerophilum 1.552874 3.825853 1.1942860 - - - hypothetical protein 0.000000e+00 0 3.259513e-02 -8.023113e-03 -6.279134e-02 -4.825513e-01 1.942419e+00 0 0 FALSE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4079778 0.4090739 U 0.4686274 0.6162291 13773 129 182396 182397 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.552874 3.825853 1.1942860 - - - hypothetical protein 1.367045 3.008058 1.0636739 5483 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.453243e-02 -8.559727e-03 -8.743016e-02 -5.148753e-01 2.064063e+00 0 0 FALSE TRUE 11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4041574 0.4074623 U 0.4686274 0.6162291 13773 129 182397 182398 1 -22 Convergent + - 0.000000 0 0.000000 0.00000000 1.367045 3.008058 1.0636739 5483 Uncharacterized conserved protein S conserved hypothetical protein 1.399879 3.096741 1.0813378 129 Dihydroxyacid dehydratase/phosphogluconate dehydratase EG dihydroxy-acid dehydratase (ilvD) 0.000000e+00 0 1.078092e-03 4.345107e-03 6.021331e-02 2.889607e-01 6.889114e-02 0 53 TRUE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5890110 0.6181692 U 0.4686274 0.6162291 13773 129 182398 182399 1 31 Same - - 2.662588 0 2.662588 2.33137949 1.399879 3.096741 1.0813378 129 Dihydroxyacid dehydratase/phosphogluconate dehydratase EG dihydroxy-acid dehydratase (ilvD) 1.475641 3.137983 1.0635526 2100 Predicted Fe-S oxidoreductase R metallo cofactor biosynthesis protein 2.350872e-02 5 5.739965e-03 -1.249143e-03 8.865352e-04 -1.376774e-01 5.599128e-01 53 5 FALSE TRUE 11 TRUE 2.9244472 1.6792360 0.5480306 2.9399224 0.7448207 0.6978676 0.4799031 0.4824847 U 0.4686274 0.8428711 13773 129 182399 182400 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.475641 3.137983 1.0635526 2100 Predicted Fe-S oxidoreductase R metallo cofactor biosynthesis protein 1.341579 2.917382 1.0286465 649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 C oxidoreductase, truncation 0.000000e+00 0 1.797286e-02 -2.662847e-03 1.873409e-02 -2.690968e-01 1.325237e+00 5 0 FALSE TRUE 10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4473191 0.4232149 U 0.4686274 0.6162291 13773 129 182400 182401 1 135 Same - - 0.000000 0 0.000000 0.00000000 1.341579 2.917382 1.0286465 649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 C oxidoreductase, truncation 1.453851 3.713231 1.1723590 - - - hypothetical protein 0.000000e+00 0 1.260502e-02 -2.699050e-04 -1.302714e-02 -9.814119e-02 8.910896e-01 0 0 FALSE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4922793 0.4474444 U 0.4686274 0.6162291 13773 129 182401 182402 1 208 Divergent - + 0.000000 0 0.000000 0.00000000 1.453851 3.713231 1.1723590 - - - hypothetical protein 1.343146 2.895621 1.0444749 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 0.000000e+00 0 1.225543e-02 -2.660516e-04 4.736776e-02 -9.731955e-02 8.780970e-01 0 7 FALSE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4928305 0.4482601 U 0.4686274 0.6162291 13773 129 182402 182403 1 72 Same + + 0.000000 0 0.000000 -0.07410797 1.343146 2.895621 1.0444749 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 1.473169 3.230688 1.0668696 61 Predicted sugar kinase G conserved hypothetical protein 1.398112e-05 7 1.690582e-02 -2.357170e-03 -3.537495e-02 -2.423571e-01 1.241779e+00 0 7 11 TRUE TRUE 9 TRUE 0.4469764 0.2976889 0.5480306 0.4469764 0.7596462 0.4392956 0.4531336 0.4263729 N 0.5492530 0.5651364 13773 129 182403 182404 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.473169 3.230688 1.0668696 61 Predicted sugar kinase G conserved hypothetical protein 1.364876 3.062657 1.0613008 1439 Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module R hypothetical protein 2.190835e-03 1 1.172743e-02 -1.883997e-03 1.651409e-02 -2.066628e-01 9.877583e-01 11 1 TRUE TRUE 10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4984228 0.4625024 0.4404584 U 0.4686274 0.6162291 13773 129 182404 182405 1 -12 Convergent + - 0.000000 0 0.000000 0.00000000 1.364876 3.062657 1.0613008 1439 Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module R hypothetical protein 1.396873 3.243631 1.1045625 170 Dolichol kinase I hypothetical protein 0.000000e+00 0 1.023819e-03 4.716933e-03 6.442910e-02 3.148128e-01 6.069057e-02 1 0 TRUE TRUE 11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5976890 0.6202452 U 0.4686274 0.6162291 13773 129 182405 182406 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.396873 3.243631 1.1045625 170 Dolichol kinase I hypothetical protein 1.531033 3.398201 1.0765664 2090 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.799889e-02 -4.341973e-03 -2.147158e-02 -3.085789e-01 1.288391e+00 0 3 FALSE TRUE 10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4377936 0.4246128 U 0.4686274 0.6162291 13773 129 182406 182407 1 43 Divergent - + 0.000000 0 0.000000 0.00000000 1.531033 3.398201 1.0765664 2090 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.377759 3.009526 1.0442571 162 Tyrosyl-tRNA synthetase J tyrosyl-tRNA synthetase 5.374391e-03 3 2.349271e-02 -5.864158e-03 -5.016560e-02 -4.124881e-01 1.656446e+00 3 9 FALSE TRUE 9 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5484663 0.4171786 0.4131718 U 0.4686274 0.6162291 13773 129 182407 182408 1 159 Convergent + - 0.000000 0 0.000000 -0.20479441 1.377759 3.009526 1.0442571 162 Tyrosyl-tRNA synthetase J tyrosyl-tRNA synthetase 1.397593 3.042974 1.0656609 1078 HD superfamily phosphohydrolases R conserved hypothetical protein 3.256383e-02 7 3.933606e-04 3.961493e-03 6.063814e-02 2.675849e-01 2.548225e-02 9 7 TRUE TRUE 10 FALSE 0.4469764 0.2714177 0.5480306 0.4469764 0.7596462 0.7542146 0.5771680 0.6352777 U 0.4686274 0.5481444 13773 129 182408 182409 1 39 Divergent - + 0.000000 0 0.000000 -0.05715841 1.397593 3.042974 1.0656609 1078 HD superfamily phosphohydrolases R conserved hypothetical protein 1.518119 3.493563 1.1816693 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 5.947392e-03 4 1.452652e-02 -3.589861e-03 -1.727972e-02 -2.703084e-01 1.108714e+00 7 4 FALSE TRUE 9 FALSE 0.4469764 0.3074832 0.5480306 0.4469764 0.7323301 0.5560231 0.4469763 0.4322833 U 0.4686274 0.5594987 13773 129 182409 182410 1 76 Convergent + - 0.000000 0 0.000000 0.00000000 1.518119 3.493563 1.1816693 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 1.443213 3.100106 1.0356260 - - - hypothetical protein 0.000000e+00 0 5.610819e-03 -5.457876e-04 3.219340e-03 1.122388e-02 3.492148e-01 4 0 TRUE TRUE 10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187914 0.5249480 U 0.4686274 0.6162291 13773 129 182410 182411 1 92 Divergent - + 0.000000 0 0.000000 0.00000000 1.443213 3.100106 1.0356260 - - - hypothetical protein 1.409182 3.069151 1.0552071 2521 Predicted archaeal methyltransferase R conserved hypothetical protein 0.000000e+00 0 1.158153e-03 3.452687e-04 2.912962e-02 -5.908792e-03 1.150683e-01 0 3 FALSE TRUE 9 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195420 0.6018877 U 0.4686274 0.6162291 13773 129 182411 182412 1 -3 Convergent + - 0.000000 0 0.000000 -0.11903382 1.409182 3.069151 1.0552071 2521 Predicted archaeal methyltransferase R conserved hypothetical protein 1.516385 3.278072 1.0856938 6 Xaa-Pro aminopeptidase E peptidase (possible proline dipeptidase) 4.538162e-03 3 1.149256e-02 -2.743396e-03 -5.136896e-03 -1.930205e-01 8.509815e-01 3 11 TRUE TRUE 10 FALSE 0.4469764 0.2932604 0.5480306 0.4469764 0.7136133 0.5411279 0.4665147 0.4503392 U 0.4686274 0.5550278 13773 129 182412 182413 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.516385 3.278072 1.0856938 6 Xaa-Pro aminopeptidase E peptidase (possible proline dipeptidase) 1.477688 3.117372 1.0575513 2411 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.497429e-03 1.709002e-03 3.174895e-02 2.077972e-01 6.570586e-02 11 0 FALSE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5527898 0.6189031 U 0.4686274 0.6162291 13773 129 182413 182414 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.477688 3.117372 1.0575513 2411 Uncharacterized conserved protein S conserved hypothetical protein 1.573615 3.651719 1.1527003 - - - hypothetical protein 0.000000e+00 0 9.201912e-03 3.213895e-03 9.449530e-02 2.806853e-01 2.184468e-01 0 0 FALSE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5844983 0.5748800 U 0.4686274 0.6162291 13773 129 182414 182415 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.573615 3.651719 1.1527003 - - - hypothetical protein 1.368685 3.137294 1.0344332 2512 Uncharacterized membrane-associated protein/domain S hypothetical protein 0.000000e+00 0 4.199612e-02 -1.010868e-02 -1.180201e-01 -5.445294e-01 2.198495e+00 0 0 TRUE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3991403 0.4057490 U 0.4686274 0.6162291 13773 129 182415 182416 1 -25 Convergent + - 0.000000 0 0.000000 0.00000000 1.368685 3.137294 1.0344332 2512 Uncharacterized membrane-associated protein/domain S hypothetical protein 1.546856 3.301628 1.0920836 - - - hypothetical protein 0.000000e+00 0 3.174485e-02 -7.895535e-03 -6.580746e-02 -4.925960e-01 1.974640e+00 0 0 TRUE TRUE 10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4057367 0.4084093 U 0.4686274 0.6162291 13773 129 182416 182417 1 210 Divergent - + 0.000000 0 0.000000 0.00000000 1.546856 3.301628 1.0920836 - - - hypothetical protein 1.381275 3.525813 1.1965049 - - - hypothetical protein 0.000000e+00 0 2.741721e-02 -6.693704e-03 -6.818461e-02 -4.220640e-01 1.714231e+00 0 0 FALSE TRUE 9 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4148039 0.4120551 U 0.4686274 0.6162291 13773 129 182417 182418 1 -21 Convergent + - 0.000000 0 0.000000 0.00000000 1.381275 3.525813 1.1965049 - - - hypothetical protein 1.400154 3.149003 1.0817517 - - - hypothetical protein 0.000000e+00 0 3.564307e-04 3.592750e-03 5.692677e-02 2.418717e-01 2.332477e-02 0 0 TRUE TRUE 10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5658236 0.6361047 U 0.4686274 0.6162291 13773 129 182418 182419 1 13 Divergent - + 0.000000 0 0.000000 0.00000000 1.400154 3.149003 1.0817517 - - - hypothetical protein 1.459439 3.130208 1.0571074 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 0.000000e+00 0 3.514718e-03 -4.122881e-04 9.414303e-03 -7.469568e-02 3.583442e-01 0 6 FALSE TRUE 9 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4998308 0.5224252 U 0.4686274 0.6162291 13773 129 182419 182420 1 209 Convergent + - 0.000000 0 0.000000 0.00000000 1.459439 3.130208 1.0571074 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 1.455737 3.467553 1.0883132 - - - paREP10 0.000000e+00 0 1.371048e-05 3.495100e-05 2.102984e-02 2.435433e-02 1.592641e-03 6 0 TRUE TRUE 10 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174041 0.6508783 U 0.4686274 0.6162291 13773 129 182420 182421 1 -6 Same - - 0.000000 0 0.000000 0.00000000 1.455737 3.467553 1.0883132 - - - paREP10 1.320508 2.924148 1.0120772 - - - hypothetical protein 0.000000e+00 0 1.828664e-02 -5.685181e-04 5.754616e-02 -1.230368e-01 1.067091e+00 0 0 FALSE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4842681 0.4350139 U 0.4686274 0.6162291 13773 129 182421 182422 1 73 Divergent - + 0.000000 0 0.000000 0.00000000 1.320508 2.924148 1.0120772 - - - hypothetical protein 1.381246 2.989644 1.0352873 1573 Uracil-DNA glycosylase L uracil DNA glycosylase (Pa-UDGa) 0.000000e+00 0 3.689025e-03 9.181163e-03 9.707870e-02 5.148300e-01 1.029115e-01 0 19 FALSE TRUE 8 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6800332 0.6052131 U 0.4686274 0.6162291 13773 129 182422 182423 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.381246 2.989644 1.0352873 1573 Uracil-DNA glycosylase L uracil DNA glycosylase (Pa-UDGa) 1.477034 3.252771 1.0508144 - - - hypothetical protein 0.000000e+00 0 9.175469e-03 -1.798682e-03 -1.111925e-02 -1.936678e-01 8.312737e-01 19 0 TRUE TRUE 9 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4662336 0.4519213 U 0.4686274 0.6162291 13773 129 182423 182424 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.477034 3.252771 1.0508144 - - - hypothetical protein 1.485731 3.425574 1.1641295 3356 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 7.563048e-05 8.804844e-04 3.235722e-02 1.393684e-01 5.889944e-03 0 0 TRUE TRUE 10 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5272388 0.6456836 U 0.4686274 0.6162291 13773 129 182424 182425 1 92 Same + + 0.000000 0 0.000000 0.00000000 1.485731 3.425574 1.1641295 3356 Predicted membrane protein S conserved hypothetical protein 1.461345 3.115790 1.0794130 468 RecA/RadA recombinase L DNA repair protein radA 0.000000e+00 0 5.946783e-04 3.417377e-04 2.199055e-02 7.873206e-02 4.987664e-02 0 12 TRUE TRUE 11 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177944 0.6238995 U 0.4686274 0.6162291 13773 129 182425 182426 1 -54 Convergent + - 0.000000 0 0.000000 0.00000000 1.461345 3.115790 1.0794130 468 RecA/RadA recombinase L DNA repair protein radA 1.430551 3.328777 1.1250653 - - - hypothetical protein 0.000000e+00 0 9.482911e-04 -2.074243e-04 1.916406e-02 -2.074203e-02 8.958605e-02 12 0 TRUE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5150814 0.6110830 U 0.4686274 0.6162291 13773 129 182426 182427 1 104 Divergent - + 0.000000 0 0.000000 0.00000000 1.430551 3.328777 1.1250653 - - - hypothetical protein 1.433432 3.069128 1.0843823 1032 Fe-S oxidoreductase C conserved hypothetical protein 0.000000e+00 0 8.303983e-06 3.743374e-04 2.483059e-02 7.861897e-03 1.357043e-03 0 5 FALSE TRUE 11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191311 0.6512883 U 0.4686274 0.6162291 13773 129 182427 182428 1 -32 Convergent + - 0.000000 0 0.000000 0.00000000 1.433432 3.069128 1.0843823 1032 Fe-S oxidoreductase C conserved hypothetical protein 1.540226 3.494127 1.1356829 - - - hypothetical protein 0.000000e+00 0 1.140496e-02 -1.595497e-03 2.130373e-02 -5.154526e-02 6.188122e-01 5 0 TRUE TRUE 12 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5064205 0.4748312 U 0.4686274 0.6162291 13773 129 182428 182429 1 46 Divergent - + 0.000000 0 0.000000 0.00000000 1.540226 3.494127 1.1356829 - - - hypothetical protein 1.382430 2.779540 0.9535519 - - - hypothetical protein containing 3 C2H2 zinc finger motifs 0.000000e+00 0 2.489956e-02 -6.126176e-03 -5.885406e-02 -4.041367e-01 1.638714e+00 0 0 FALSE TRUE 11 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4186761 0.4137816 U 0.4686274 0.6162291 13773 129 182429 182430 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.382430 2.779540 0.9535519 - - - hypothetical protein containing 3 C2H2 zinc finger motifs 1.435331 3.235435 1.0851104 575 CDP-diglyceride synthetase I conserved hypothetical protein 0.000000e+00 0 2.798527e-03 1.107634e-03 2.226610e-02 3.299075e-02 2.573440e-01 0 12 TRUE TRUE 12 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174985 0.5597228 U 0.4686274 0.6162291 13773 129 182430 182431 1 31 Same + + 0.000000 0 0.000000 -0.04082199 1.435331 3.235435 1.0851104 575 CDP-diglyceride synthetase I conserved hypothetical protein 1.480693 3.181112 1.0807664 1436 Archaeal/vacuolar-type H+-ATPase subunit F C H+-transporting ATP synthase subunit F (atpF) 2.507089e-02 1 2.057671e-03 -4.706015e-04 1.676034e-02 -2.162081e-02 1.840496e-01 0 12 1 TRUE TRUE 13 TRUE 0.4469764 0.3084868 0.5480306 0.4469764 0.6329203 0.7074534 0.5146053 0.5841817 N 0.5492530 0.5685144 13773 129 182431 182432 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.480693 3.181112 1.0807664 1436 Archaeal/vacuolar-type H+-ATPase subunit F C H+-transporting ATP synthase subunit F (atpF) 1.473877 3.271322 1.0912879 1390 Archaeal/vacuolar-type H+-ATPase subunit E C conserved hypothetical protein 0.000000e+00 0 4.645702e-05 6.587920e-04 2.754413e-02 1.129403e-01 4.356203e-03 C 1 0 TRUE TRUE 14 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5203215 0.6468997 Y 1.4497162 0.7118045 13773 129 182432 182433 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.473877 3.271322 1.0912879 1390 Archaeal/vacuolar-type H+-ATPase subunit E C conserved hypothetical protein 1.430018 3.137657 1.1121859 1155 Archaeal/vacuolar-type H+-ATPase subunit A C H+-transporting ATP synthase subunit A (atpA) 0.000000e+00 0 1.923657e-03 -4.806068e-04 1.499478e-02 -3.554228e-02 1.775235e-01 C 0 20 TRUE TRUE 15 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5105544 0.5856408 Y 1.4497162 0.7118045 13773 129 182433 182434 1 72 Same + + 0.000000 0 0.000000 -0.50595881 1.430018 3.137657 1.1121859 1155 Archaeal/vacuolar-type H+-ATPase subunit A C H+-transporting ATP synthase subunit A (atpA) 1.467477 3.379035 1.1349873 2012 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 K DNA-directed RNA polymerase subunit H (rpoH) 1.002631e-01 8 1.403188e-03 -3.437974e-04 1.621455e-02 -2.855916e-02 1.306631e-01 0 20 8 TRUE TRUE 16 TRUE 0.4469764 0.2345012 0.5480306 0.4469764 0.7652913 1.0147250 0.5125343 0.5980793 N 0.5492530 0.5452573 13773 129 182434 182435 1 35 Same + + 5.252855 0 5.252855 5.25285499 1.467477 3.379035 1.1349873 2012 DNA-directed RNA polymerase, subunit H, RpoH/RPB5 K DNA-directed RNA polymerase subunit H (rpoH) 1.401497 3.062589 1.1034570 85 DNA-directed RNA polymerase, beta subunit/140 kD subunit K DNA-directed RNA polymerase subunit B (rpoB) 2.159066e-02 5 4.353326e-03 -8.025189e-04 1.701982e-02 -9.882973e-02 4.205567e-01 K 8 5 TRUE TRUE 17 TRUE 2.8074821 1.7735348 0.5480306 2.8807799 0.7448207 0.6890474 0.4917185 0.5086682 Y 1.4497162 0.9042173 13773 129 182435 182436 1 81 Same + + 10.271458 0 18.468344 18.46834435 1.401497 3.062589 1.1034570 85 DNA-directed RNA polymerase, beta subunit/140 kD subunit K DNA-directed RNA polymerase subunit B (rpoB) 1.461352 3.145309 1.0931112 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A' (rpoA1) 6.125049e-02 5 3.582643e-03 -4.969292e-04 8.856990e-03 -7.745276e-02 3.546783e-01 K 5 15 TRUE TRUE 18 TRUE 2.6699663 1.9069313 0.5480306 2.6213427 0.7448207 0.8869692 0.4989522 0.5237241 Y 1.4497162 0.9192352 13773 129 182436 182437 1 -3 Same + + 18.587903 0 29.054334 29.05433401 1.461352 3.145309 1.0931112 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A' (rpoA1) 1.479372 3.300530 1.1238339 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A'' (rpoA2) 1.911116e-01 10 3.247026e-04 2.786503e-04 2.573182e-02 6.905959e-02 2.824876e-02 K 15 10 TRUE TRUE 19 TRUE 2.4427799 1.9604677 0.5480306 2.4566331 0.7739415 1.1342961 0.5181514 0.6339124 Y 1.4497162 0.9261075 13773 129 182437 182438 1 42 Same + + 18.587903 0 29.054334 29.05433401 1.479372 3.300530 1.1238339 86 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K DNA-directed RNA polymerase subunit A'' (rpoA2) 1.442267 3.166333 1.0353452 1911 Ribosomal protein L30E J ribosomal protein L30 2.824945e-01 10 1.376742e-03 -2.553247e-04 1.597588e-02 3.314861e-03 1.230109e-01 0 10 10 TRUE TRUE 20 TRUE 2.4427799 1.9604677 0.5480306 2.4566331 0.7739415 1.2156130 0.5196876 0.6000329 N 0.5492530 0.8940859 13773 129 182438 182439 1 -7 Same + + 22.613255 0 33.079686 33.07968570 1.442267 3.166333 1.0353452 1911 Ribosomal protein L30E J ribosomal protein L30 1.427963 3.018300 1.0258867 195 Transcription elongation factor K transcription termination factor NusA, putative 3.229691e-01 10 2.046084e-04 2.138117e-04 2.442023e-02 -1.279296e-03 2.193945e-02 0 10 12 TRUE TRUE 21 TRUE 2.2795894 1.9957100 0.5480306 2.3656937 0.7739415 1.2322996 0.5199861 0.6367684 N 0.5492530 0.9000975 13773 129 182439 182440 1 40 Same + + 25.178204 0 35.644635 35.57052708 1.427963 3.018300 1.0258867 195 Transcription elongation factor K transcription termination factor NusA, putative 1.517977 3.220900 1.0705886 48 Ribosomal protein S12 J ribosomal protein S12 2.494397e-01 12 8.102452e-03 -1.560045e-03 1.236182e-02 -8.454013e-02 5.587649e-01 0 12 21 TRUE TRUE 22 TRUE 2.2337636 2.0043252 0.5480306 2.3298499 0.7776747 1.1893544 0.4969205 0.4827099 N 0.5492530 0.9015855 13773 129 182440 182441 1 0 Same + + 0.000000 0 0.000000 -0.92112870 1.517977 3.220900 1.0705886 48 Ribosomal protein S12 J ribosomal protein S12 1.611317 3.524142 1.0447276 202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K DNA-directed RNA polymerase subunit D (rpoD) 1.996510e-01 10 8.712443e-03 1.064838e-02 1.989327e-01 5.399359e-01 7.761120e-02 0 21 10 TRUE TRUE 23 TRUE 0.4469764 0.2135106 0.5480306 0.4469764 0.7739415 1.1405219 0.6927097 0.6156404 N 0.5492530 0.5386183 13773 129 182441 182442 1 26 Same + + 17.903724 0 26.172931 25.93630402 1.611317 3.524142 1.0447276 202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K DNA-directed RNA polymerase subunit D (rpoD) 1.675620 3.718358 1.1107052 1727 Ribosomal protein L18E J ribosomal protein L18 2.561589e-01 10 4.134875e-03 3.585940e-02 5.027470e-01 8.470116e-01 4.561173e-03 0 10 11 TRUE TRUE 24 TRUE 2.4985447 1.9424973 0.5480306 2.5004783 0.7739415 1.1936934 0.7936739 0.6466721 N 0.5492530 0.8912296 13773 129 182442 182443 1 -3 Same + + 2.856470 0 2.856470 2.85647021 1.675620 3.718358 1.1107052 1727 Ribosomal protein L18E J ribosomal protein L18 1.559078 3.416298 1.0931771 102 Ribosomal protein L13 J ribosomal protein L13 2.013490e-03 4 1.358202e-02 2.414600e-02 2.048269e-01 7.371053e-01 3.336300e-02 J 11 4 TRUE TRUE 25 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.7323301 0.4971904 0.7639694 0.6308211 Y 1.4497162 0.8983990 13773 129 182443 182444 1 3 Same + + 9.921229 0 9.921229 9.92122923 1.559078 3.416298 1.0931771 102 Ribosomal protein L13 J ribosomal protein L13 1.481957 3.186751 1.0628071 103 Ribosomal protein S9 J ribosomal protein S9 1.076711e-02 4 5.947705e-03 3.291298e-03 3.214427e-02 2.944866e-01 1.525973e-01 J 4 61 TRUE TRUE 26 TRUE 2.6834842 1.8372876 0.5480306 2.7639756 0.7323301 0.6051389 0.5906193 0.5925944 Y 1.4497162 0.9122634 13773 129 182444 182445 1 -3 Same + + 18.327019 0 26.000242 26.00024212 1.481957 3.186751 1.0628071 103 Ribosomal protein S9 J ribosomal protein S9 1.670931 3.630324 1.1398977 1644 DNA-directed RNA polymerase, subunit N (RpoN/RPB10) K DNA-directed RNA polymerase subunit N (rpoN) 3.478049e-03 10 3.571126e-02 6.709971e-03 2.192171e-01 3.629855e-01 3.251538e-01 0 61 10 TRUE TRUE 27 TRUE 2.4649028 1.9446050 0.5480306 2.5155966 0.7739415 0.5249581 0.6164480 0.5328194 N 0.5492530 0.8918925 13773 129 182445 182446 1 51 Same + + 0.000000 0 0.000000 -0.47773506 1.670931 3.630324 1.1398977 1644 DNA-directed RNA polymerase, subunit N (RpoN/RPB10) K DNA-directed RNA polymerase subunit N (rpoN) 1.529164 3.474018 1.0997856 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 1.536325e-01 5 2.009794e-02 1.707372e-02 1.133313e-01 6.405196e-01 7.761120e-02 K 10 5 TRUE TRUE 28 TRUE 0.4469764 0.2362422 0.5480306 0.4469764 0.7448207 1.0896394 0.7335863 0.6156404 Y 1.4497162 0.6408257 13773 129 182446 182447 1 -3 Same + + 2.856470 0 5.519058 5.17283251 1.529164 3.474018 1.0997856 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 1.586811 3.346168 1.0734790 1812 Archaeal S-adenosylmethionine synthetase E S-adenosylmethionine synthetase 1.081314e-01 5 3.323241e-03 1.053164e-02 1.750868e-01 5.671698e-01 2.876708e-02 0 5 17 TRUE TRUE 29 TRUE 2.8950318 1.7696075 0.5480306 2.8617306 0.7448207 1.0410001 0.7059525 0.6337043 N 0.5492530 0.8622286 13773 129 182447 182448 1 -3 Convergent + - 2.856470 0 2.856470 2.65412978 1.586811 3.346168 1.0734790 1812 Archaeal S-adenosylmethionine synthetase E S-adenosylmethionine synthetase 1.534233 3.314624 1.0923695 2433 Uncharacterized conserved protein S conserved hypothetical protein 6.260434e-02 3 2.764466e-03 1.121813e-02 1.227607e-01 5.859246e-01 2.171269e-02 17 3 TRUE TRUE 30 FALSE 2.8950318 1.7019611 0.5480306 2.9213001 0.7136133 0.8950258 0.7156244 0.6368386 U 0.4686274 0.8471407 13773 129 182448 182449 1 4 Same - - 4.709530 0 4.709530 4.70953020 1.534233 3.314624 1.0923695 2433 Uncharacterized conserved protein S conserved hypothetical protein 1.507550 3.268900 1.0491751 478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain T conserved hypothetical protein 3.883766e-02 3 7.119725e-04 4.652117e-03 6.571287e-02 3.858137e-01 1.972483e-02 3 8 FALSE TRUE 29 TRUE 2.8468194 1.7578659 0.5480306 2.8992734 0.7136133 0.7951321 0.6279314 0.6377141 U 0.4686274 0.8568728 13773 129 182449 182450 1 32 Divergent - + 0.000000 0 0.000000 0.00000000 1.507550 3.268900 1.0491751 478 RIO-like serine/threonine protein kinase fused to N-terminal HTH domain T conserved hypothetical protein 1.603785 3.508340 1.1084712 1860 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 9.261108e-03 8.557980e-03 1.717672e-01 4.833318e-01 9.997827e-02 8 0 FALSE TRUE 28 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6675957 0.6068453 U 0.4686274 0.6162291 13773 129 182450 182451 1 153 Same + + 0.000000 0 0.000000 0.00000000 1.603785 3.508340 1.1084712 1860 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.506131 3.243251 1.0491179 615 Cytidylyltransferase MI cytidyltransferase 0.000000e+00 0 9.536330e-03 8.341662e-03 6.690375e-02 4.726356e-01 1.078944e-01 0 3 TRUE TRUE 29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6634656 0.6036927 U 0.4686274 0.6162291 13773 129 182451 182452 1 -19 Same + + 0.000000 0 0.000000 -0.26504093 1.506131 3.243251 1.0491179 615 Cytidylyltransferase MI cytidyltransferase 1.528404 3.437596 1.1448441 1515 Deoxyinosine 3'endonuclease (endonuclease V) L DNA endonuclease V, conjectural 7.475750e-02 3 4.960679e-04 4.215419e-03 7.747745e-02 3.635338e-01 1.623033e-02 3 13 TRUE TRUE 30 TRUE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.9356931 0.6167280 0.6396093 U 0.4686274 0.5447277 13773 129 182452 182453 1 -35 Convergent + - 0.000000 0 0.000000 -0.14066733 1.528404 3.437596 1.1448441 1515 Deoxyinosine 3'endonuclease (endonuclease V) L DNA endonuclease V, conjectural 1.455859 3.313309 1.1106567 589 Universal stress protein UspA and related nucleotide-binding proteins T conserved protein (probable universal stress protein homolog) 9.761268e-03 13 5.262697e-03 3.439481e-04 9.748957e-03 9.255458e-02 2.828640e-01 0 13 21 TRUE TRUE 31 FALSE 0.4469764 0.2780518 0.5480306 0.4469764 0.7781369 0.5967066 0.5179259 0.5499819 N 0.5492530 0.5589778 13773 129 182453 182454 1 9 Same - - 0.000000 0 0.000000 -0.41836851 1.455859 3.313309 1.1106567 589 Universal stress protein UspA and related nucleotide-binding proteins T conserved protein (probable universal stress protein homolog) 1.456185 3.646183 1.2198697 395 ABC-type sugar transport system, permease component G multiple sugar transport permease protein 9.566906e-07 7 1.061961e-07 2.140274e-05 2.099560e-02 1.950749e-02 9.423910e-06 0 21 7 FALSE TRUE 30 TRUE 0.4469764 0.2396649 0.5480306 0.4469764 0.7596462 0.4385512 0.5177085 0.6557762 N 0.5492530 0.5468881 13773 129 182454 182455 1 -3 Same - - 10.796698 0 10.796698 10.79669797 1.456185 3.646183 1.2198697 395 ABC-type sugar transport system, permease component G multiple sugar transport permease protein 1.534772 3.792910 1.1450516 1175 ABC-type sugar transport systems, permease components G multiple sugar transport permease protein 8.290044e-02 7 6.175893e-03 3.995617e-04 4.300596e-02 9.840447e-02 3.087367e-01 G 7 7 FALSE TRUE 29 TRUE 2.6465843 1.8555306 0.5480306 2.7405335 0.7596462 0.9554719 0.5184479 0.5390834 Y 1.4497162 0.9144646 13773 129 182455 182456 1 -3 Same - - 5.341377 0 5.341377 5.34137686 1.534772 3.792910 1.1450516 1175 ABC-type sugar transport systems, permease components G multiple sugar transport permease protein 1.448880 3.278508 1.1202205 1653 ABC-type sugar transport system, periplasmic component G multiple sugar binding protein 2.545656e-02 6 7.377397e-03 -2.095152e-04 6.492144e-04 5.027185e-02 3.902653e-01 G 7 6 FALSE TRUE 28 TRUE 2.8043759 1.7755009 0.5480306 2.8785340 0.7537284 0.7135383 0.5187825 0.5139757 Y 1.4497162 0.9044674 13773 129 182456 182457 1 351 Same - - 0.000000 0 0.000000 0.00000000 1.448880 3.278508 1.1202205 1653 ABC-type sugar transport system, periplasmic component G multiple sugar binding protein 1.304477 2.760473 0.9599884 515 Serine/threonine protein kinase RTKL hypothetical protein with partial (eukaryotic) protein kinase domain 0.000000e+00 0 2.085222e-02 3.691709e-04 7.985149e-02 -6.737978e-02 1.012317e+00 6 0 FALSE TRUE 27 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5016752 0.4385224 U 0.4686274 0.6162291 13773 129 182457 182458 1 988 Divergent - + 0.000000 0 0.000000 0.00000000 1.304477 2.760473 0.9599884 515 Serine/threonine protein kinase RTKL hypothetical protein with partial (eukaryotic) protein kinase domain 1.417163 3.172757 1.0971227 2888 Predicted Zn-ribbon RNA-binding protein with a function in translation J conserved hypothetical protein 0.000000e+00 0 1.269816e-02 5.028880e-03 2.769885e-02 2.279444e-01 4.760259e-01 0 5 FALSE TRUE 26 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5611667 0.4973638 U 0.4686274 0.6162291 13773 129 182458 182459 1 49 Same + + 8.260148 0 10.922736 10.92273592 1.417163 3.172757 1.0971227 2888 Predicted Zn-ribbon RNA-binding protein with a function in translation J conserved hypothetical protein 1.457872 3.114651 1.0767286 2092 Translation elongation factor EF-1beta J translation elongation factor aEF-1 beta subunit 1.764724e-01 4 1.657209e-03 -2.217792e-04 1.527572e-02 -3.783464e-02 1.592641e-01 J 5 4 TRUE TRUE 27 TRUE 2.7009158 1.8575661 0.5480306 2.7323856 0.7323301 1.1158155 0.5095597 0.5901897 Y 1.4497162 0.9141400 13773 129 182459 182460 1 37 Same + + 2.856470 0 5.519058 5.44109649 1.457872 3.114651 1.0767286 2092 Translation elongation factor EF-1beta J translation elongation factor aEF-1 beta subunit 1.405790 3.072276 1.0841143 464 ATPases of the AAA+ class O AAA family ATPase, possible cell division control protein cdc48 6.873549e-02 4 2.712519e-03 -2.954666e-04 2.245758e-02 -5.484834e-02 2.589037e-01 0 4 8 TRUE TRUE 28 TRUE 2.8950318 1.7794383 0.5480306 2.8617306 0.7323301 0.9113849 0.5053493 0.5586400 N 0.5492530 0.8637098 13773 129 182460 182461 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.405790 3.072276 1.0841143 464 ATPases of the AAA+ class O AAA family ATPase, possible cell division control protein cdc48 1.374202 3.030051 1.0265470 - - - hypothetical protein 0.000000e+00 0 9.978250e-04 3.520121e-03 7.174632e-02 2.248239e-01 7.933107e-02 8 0 TRUE TRUE 29 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5594899 0.6149078 U 0.4686274 0.6162291 13773 129 182461 182462 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.374202 3.030051 1.0265470 - - - hypothetical protein 1.458238 3.234157 1.1037918 258 5'-3' exonuclease (including N-terminal domain of PolI) L DNA endonuclease rad2 homolog 0.000000e+00 0 7.062111e-03 -5.283956e-04 -4.530298e-04 -9.997591e-02 6.285094e-01 0 12 TRUE TRUE 30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4911487 0.4734023 U 0.4686274 0.6162291 13773 129 182462 182463 1 100 Same + + 0.000000 0 0.000000 0.00000000 1.458238 3.234157 1.1037918 258 5'-3' exonuclease (including N-terminal domain of PolI) L DNA endonuclease rad2 homolog 1.416936 2.937037 1.0414794 - - - hypothetical protein 0.000000e+00 0 1.705894e-03 -2.358695e-04 2.087599e-02 -3.875878e-02 1.629606e-01 12 0 TRUE TRUE 31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5094264 0.5893580 U 0.4686274 0.6162291 13773 129 182463 182464 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.416936 2.937037 1.0414794 - - - hypothetical protein 1.493940 3.158960 1.0693755 2518 Protein-L-isoaspartate carboxylmethyltransferase O protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 0.000000e+00 0 5.929644e-03 -1.466050e-03 5.178214e-03 -1.145747e-01 5.061400e-01 0 25 TRUE TRUE 32 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4867505 0.4920423 U 0.4686274 0.6162291 13773 129 182464 182465 1 49 Same + + 0.000000 0 0.000000 0.00000000 1.493940 3.158960 1.0693755 2518 Protein-L-isoaspartate carboxylmethyltransferase O protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 1.588435 3.511747 1.1141816 - - - hypothetical protein 0.000000e+00 0 8.929333e-03 5.830733e-03 1.320085e-01 3.936945e-01 1.454869e-01 25 0 TRUE TRUE 33 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6314933 0.5941308 U 0.4686274 0.6162291 13773 129 182465 182466 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.588435 3.511747 1.1141816 - - - hypothetical protein 1.473173 3.170192 1.0708623 17 Aspartyl/asparaginyl-tRNA synthetases J aspartyl-tRNA synthetase 0.000000e+00 0 1.328523e-02 2.984856e-03 9.148815e-03 2.514187e-01 3.019515e-01 0 16 TRUE TRUE 34 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5697142 0.5408188 U 0.4686274 0.6162291 13773 129 182466 182467 1 29 Same - - 5.689684 0 8.352271 8.17005866 1.473173 3.170192 1.0708623 17 Aspartyl/asparaginyl-tRNA synthetases J aspartyl-tRNA synthetase 1.438518 3.297946 1.0985380 195 Transcription elongation factor K conserved hypothetical protein 8.869744e-02 4 1.201012e-03 -2.804259e-04 1.667511e-02 -8.889693e-03 1.068883e-01 0 16 4 FALSE TRUE 33 TRUE 2.7798012 1.8211872 0.5480306 2.7963516 0.7323301 0.9756975 0.5189598 0.6041306 N 0.5492530 0.8714599 13773 129 182467 182468 1 56 Divergent - + 0.000000 0 0.000000 -0.24283734 1.438518 3.297946 1.0985380 195 Transcription elongation factor K conserved hypothetical protein 1.477808 3.210964 1.1189925 1031 Uncharacterized Fe-S oxidoreductase C conserved hypothetical protein 2.516522e-02 4 1.543741e-03 -3.400998e-04 1.811219e-02 -1.038279e-02 1.419954e-01 0 4 9 FALSE TRUE 32 FALSE 0.4469764 0.2674215 0.5480306 0.4469764 0.7323301 0.7110956 0.5183971 0.5953411 N 0.5492530 0.5556362 13773 129 182468 182469 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.477808 3.210964 1.1189925 1031 Uncharacterized Fe-S oxidoreductase C conserved hypothetical protein 1.457843 3.459005 1.0962705 - - - hypothetical protein 0.000000e+00 0 3.986003e-04 1.703912e-04 2.106361e-02 5.324509e-02 3.740350e-02 9 0 TRUE TRUE 33 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187741 0.6288792 U 0.4686274 0.6162291 13773 129 182469 182470 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.457843 3.459005 1.0962705 - - - hypothetical protein 1.345140 2.997902 1.0624215 1990 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.270206e-02 -6.853789e-04 4.128867e-02 -1.242778e-01 9.276809e-01 0 12 FALSE TRUE 32 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4837903 0.4451969 U 0.4686274 0.6162291 13773 129 182470 182471 1 68 Divergent - + 0.000000 0 0.000000 -0.13353139 1.345140 2.997902 1.0624215 1990 Uncharacterized conserved protein S conserved hypothetical protein 1.377894 3.092691 1.1020822 1404 Subtilisin-like serine proteases O surface layer-associated STABLE protease, conjectural 2.507089e-02 1 1.072845e-03 7.809451e-03 9.709626e-02 4.865477e-01 4.357616e-02 12 1 FALSE TRUE 31 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7074534 0.6689872 0.6264906 U 0.4686274 0.5517368 13773 129 182471 182472 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.377894 3.092691 1.1020822 1404 Subtilisin-like serine proteases O surface layer-associated STABLE protease, conjectural 1.378067 2.960785 0.9600185 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein) 1.851224e-04 1 2.995893e-08 5.389331e-03 8.368672e-02 3.597224e-01 5.300950e-06 1 1 TRUE TRUE 32 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4421536 0.6156101 0.6558673 U 0.4686274 0.6162291 13773 129 182472 182473 1 39 Same - - 0.000000 0 0.000000 0.00000000 1.378067 2.960785 0.9600185 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR diadenosine 5'5'''-P1,P4-tetraphosphate pyrophosphohydrolase (mutT/nudix family protein) 1.556987 3.421709 1.0592727 - - - hypothetical protein 0.000000e+00 0 3.201242e-02 -7.742783e-03 -5.513105e-02 -4.580374e-01 1.859885e+00 1 0 FALSE TRUE 31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4106426 0.4101998 U 0.4686274 0.6162291 13773 129 182473 182474 1 121 Divergent - + 0.000000 0 0.000000 0.00000000 1.556987 3.421709 1.0592727 - - - hypothetical protein 1.497439 3.252468 1.1152715 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C succinate dehydrogenase flavoprotein subunit (sdhA) 0.000000e+00 0 3.546028e-03 4.862213e-03 5.465634e-02 3.746511e-01 7.591019e-02 0 53 FALSE TRUE 30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6224034 0.6161199 U 0.4686274 0.6162291 13773 129 182474 182475 1 2 Same + + 49.470850 0 126.457846 124.95876164 1.497439 3.252468 1.1152715 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C succinate dehydrogenase flavoprotein subunit (sdhA) 1.544686 3.292449 1.0205997 479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit C succinate dehydrogenase iron-sulfur subunit (sdhB) 1.894379e-01 37 2.232324e-03 4.295798e-03 8.768407e-02 3.566137e-01 5.696813e-02 C 53 37 TRUE TRUE 31 TRUE 2.0596879 2.0764720 0.5480306 2.0452694 0.7740003 1.1301638 0.6150533 0.6214366 Y 1.4497162 0.9384094 13773 129 182475 182476 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.544686 3.292449 1.0205997 479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit C succinate dehydrogenase iron-sulfur subunit (sdhB) 1.519127 3.579199 1.1084342 2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit C succinate dehydrogenase cytochrome b subunit (sdhC) 9.459415e-03 1 6.532584e-04 6.319200e-03 8.417167e-02 4.477235e-01 1.290133e-02 C 37 1 TRUE TRUE 32 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5912015 0.6550709 0.6415107 Y 1.4497162 0.7118045 13773 129 182476 182477 1 -9 Same + + 0.000000 0 0.000000 0.00000000 1.519127 3.579199 1.1084342 2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit C succinate dehydrogenase cytochrome b subunit (sdhC) 1.411995 3.150073 1.1135566 - - - succinate dehydrogenase subunit D (sdhD) 0.000000e+00 0 1.147740e-02 -2.668608e-03 -1.817380e-02 -1.802217e-01 8.242912e-01 1 0 TRUE TRUE 33 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4703678 0.4526824 U 0.4686274 0.6162291 13773 129 182477 182478 1 78 Convergent + - 0.000000 0 0.000000 0.00000000 1.411995 3.150073 1.1135566 - - - succinate dehydrogenase subunit D (sdhD) 1.461261 3.259644 1.0396403 592 DNA polymerase sliding clamp subunit (PCNA homolog) L proliferating-cell nuclear antigen homolog (PCNA) 0.000000e+00 0 2.427195e-03 -3.888017e-04 1.249720e-02 -5.534898e-02 2.322900e-01 0 0 TRUE TRUE 34 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5052041 0.5700736 U 0.4686274 0.6162291 13773 129 182478 182479 1 94 Same - - 0.000000 0 0.000000 0.00000000 1.461261 3.259644 1.0396403 592 DNA polymerase sliding clamp subunit (PCNA homolog) L proliferating-cell nuclear antigen homolog (PCNA) 1.481723 3.215559 1.0810318 2025 Electron transfer flavoprotein, alpha subunit C electron transfer flavoprotein alpha subunit (etfA) 0.000000e+00 0 4.186927e-04 2.993189e-04 2.632629e-02 7.157696e-02 3.622551e-02 0 0 27 FALSE TRUE 33 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180132 0.6294602 N 0.5492530 0.6245624 13773 129 182479 182480 1 4 Same - - 14.647654 0 20.616646 20.45999205 1.481723 3.215559 1.0810318 2025 Electron transfer flavoprotein, alpha subunit C electron transfer flavoprotein alpha subunit (etfA) 1.511412 3.362528 1.0919442 2086 Electron transfer flavoprotein, beta subunit C electron transfer flavoprotein beta subunit (etfB) 1.063920e-01 13 8.814143e-04 1.820414e-03 4.883436e-02 2.167676e-01 3.710724e-02 C 27 13 FALSE TRUE 32 TRUE 2.5807442 1.9173401 0.5480306 2.5842504 0.7781369 1.0296554 0.5558901 0.6290639 Y 1.4497162 0.9210227 13773 129 182480 182481 1 5 Same - - 7.375256 0 11.957953 11.63959703 1.511412 3.362528 1.0919442 2086 Electron transfer flavoprotein, beta subunit C electron transfer flavoprotein beta subunit (etfB) 1.563979 3.134248 1.0070269 2440 Ferredoxin-like protein C ferredoxin like protein 1.299447e-01 9 2.763312e-03 6.757341e-03 1.227884e-01 4.506485e-01 4.683919e-02 C 13 9 FALSE TRUE 31 TRUE 2.7415630 1.8636829 0.5480306 2.7069324 0.7702221 1.0660153 0.6560635 0.6252488 Y 1.4497162 0.9143559 13773 129 182481 182482 1 -3 Same - - 11.431860 0 20.776731 19.79641869 1.563979 3.134248 1.0070269 2440 Ferredoxin-like protein C ferredoxin like protein 1.468039 3.287520 1.1047414 644 Dehydrogenases (flavoproteins) C electron transfer flavoprotein-quinone oxidoreductase 3.262134e-01 9 9.204442e-03 1.874181e-03 1.116482e-02 1.953818e-01 2.919151e-01 C 9 10 FALSE TRUE 30 TRUE 2.6271063 1.9152549 0.5480306 2.5732548 0.7702221 1.2401595 0.5482041 0.5460473 Y 1.4497162 0.9204092 13773 129 182482 182483 1 227 Divergent - + 0.000000 0 0.000000 -0.13150953 1.468039 3.287520 1.1047414 644 Dehydrogenases (flavoproteins) C electron transfer flavoprotein-quinone oxidoreductase 1.566953 3.232723 1.0475742 314 Molybdopterin converting factor, large subunit H molybdenum cofactor biosynthesis protein D/E 2.239266e-02 4 9.783892e-03 1.923684e-03 7.643922e-02 1.970940e-01 2.994265e-01 0 10 4 FALSE TRUE 29 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7323301 0.6954998 0.5486826 0.5419791 N 0.5492530 0.5624819 13773 129 182483 182484 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.566953 3.232723 1.0475742 314 Molybdopterin converting factor, large subunit H molybdenum cofactor biosynthesis protein D/E 1.550522 3.342141 1.0368591 - - - hypothetical protein 0.000000e+00 0 2.699943e-04 1.145532e-02 1.457180e-01 5.912821e-01 2.643996e-03 4 0 TRUE TRUE 30 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7168517 0.6490066 U 0.4686274 0.6162291 13773 129 182484 182485 1 62 Divergent - + 0.000000 0 0.000000 0.00000000 1.550522 3.342141 1.0368591 - - - hypothetical protein 1.507934 3.300540 1.1026331 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 0.000000e+00 0 1.813724e-03 5.604816e-03 6.943478e-02 4.137833e-01 3.506637e-02 0 0 FALSE TRUE 29 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6409571 0.6299706 U 0.4686274 0.6162291 13773 129 182485 182486 1 158 Same + + 0.000000 0 0.000000 0.00000000 1.507934 3.300540 1.1026331 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 1.529822 3.510185 1.1240768 - - - hypothetical protein 0.000000e+00 0 4.790893e-04 4.434437e-03 8.008867e-02 3.762055e-01 1.433377e-02 0 0 TRUE TRUE 30 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6235560 0.6407068 U 0.4686274 0.6162291 13773 129 182486 182487 1 27 Same + + 0.000000 0 0.000000 0.00000000 1.529822 3.510185 1.1240768 - - - hypothetical protein 1.774121 3.865169 1.0810407 1321 Mn-dependent transcriptional regulator K transcriptional regulatory protein, conjectural 0.000000e+00 0 5.968212e-02 2.531123e-02 5.655616e-01 6.673106e-01 9.660981e-02 0 0 TRUE TRUE 31 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7430736 0.6082362 U 0.4686274 0.6162291 13773 129 182487 182488 1 68 Same + + 0.000000 0 0.000000 0.00000000 1.774121 3.865169 1.0810407 1321 Mn-dependent transcriptional regulator K transcriptional regulatory protein, conjectural 1.629488 3.640615 1.0838041 - - - hypothetical protein 0.000000e+00 0 2.091863e-02 5.747641e-02 5.088174e-01 8.960596e-01 6.248642e-03 0 0 TRUE TRUE 32 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8037042 0.6452751 U 0.4686274 0.6162291 13773 129 182488 182489 1 34 Same + + 0.000000 0 0.000000 0.00000000 1.629488 3.640615 1.0838041 - - - hypothetical protein 1.545998 3.281015 1.0861481 49 Ribosomal protein S7 J ribosomal protein S7 0.000000e+00 0 6.970607e-03 1.684876e-02 1.599191e-01 6.640317e-01 3.115780e-02 0 10 TRUE TRUE 33 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7409004 0.6322033 U 0.4686274 0.6162291 13773 129 182489 182490 1 31 Same + + 0.000000 0 0.000000 -0.72456721 1.545998 3.281015 1.0861481 49 Ribosomal protein S7 J ribosomal protein S7 1.446341 3.123984 1.0658057 470 ATPase involved in DNA replication L replication factor C small subunit 2.329131e-01 9 9.931611e-03 -4.779656e-04 -7.514997e-03 3.255608e-02 4.717992e-01 0 10 9 TRUE TRUE 34 TRUE 0.4469764 0.2236322 0.5480306 0.4469764 0.7702221 1.1625725 0.5174486 0.4985726 N 0.5492530 0.5418215 13773 129 182490 182491 1 0 Same + + 8.154788 0 10.817375 10.46748014 1.446341 3.123984 1.0658057 470 ATPase involved in DNA replication L replication factor C small subunit 1.491355 3.314207 1.0856591 470 ATPase involved in DNA replication L replication factor C large subunit 1.673255e-01 9 2.026267e-03 -2.018957e-04 2.236772e-02 2.001874e-02 1.642022e-01 L 9 10 TRUE TRUE 35 TRUE 2.7051684 1.8514647 0.5480306 2.7364805 0.7702221 1.1076963 0.5176648 0.5889325 Y 1.4497162 0.9134862 13773 129 182491 182492 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.491355 3.314207 1.0856591 470 ATPase involved in DNA replication L replication factor C large subunit 1.579914 3.227904 0.8328345 - - - hypothetical protein 0.000000e+00 0 7.842832e-03 5.135964e-03 1.186805e-01 3.720725e-01 1.425743e-01 10 0 TRUE TRUE 36 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6212567 0.5949759 U 0.4686274 0.6162291 13773 129 182492 182493 1 75 Same + + 0.000000 0 0.000000 0.00000000 1.579914 3.227904 0.8328345 - - - hypothetical protein 1.573594 3.504286 1.1244681 1474 Cdc6-related protein, AAA superfamily ATPase LO cell division control protein 6 (cdc6), putative 0.000000e+00 0 3.994830e-05 1.570549e-02 2.003464e-01 6.717623e-01 2.355978e-04 0 9 TRUE TRUE 37 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7439457 0.6542630 U 0.4686274 0.6162291 13773 129 182493 182494 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.573594 3.504286 1.1244681 1474 Cdc6-related protein, AAA superfamily ATPase LO cell division control protein 6 (cdc6), putative 1.676340 3.832508 1.0965121 640 Predicted transcriptional regulators K transcriptional regulatory protein (helix-turn-helix), putative 1.765169e-03 1 1.055679e-02 2.748883e-02 4.327245e-01 7.758293e-01 2.059655e-02 9 1 TRUE TRUE 38 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4899807 0.7758723 0.6372565 U 0.4686274 0.6162291 13773 129 182494 182495 1 17 Same + + 0.000000 0 0.000000 0.00000000 1.676340 3.832508 1.0965121 640 Predicted transcriptional regulators K transcriptional regulatory protein (helix-turn-helix), putative 1.583132 3.415148 1.0717436 4998 Predicted endonuclease (RecB family) L conserved hypothetical protein 0.000000e+00 0 8.687758e-03 2.963440e-02 2.828026e-01 7.978283e-01 1.451812e-02 0 1 0 TRUE TRUE 39 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7851838 0.6405817 N 0.5492530 0.6245624 13773 129 182495 182496 1 75 Same + + 0.000000 0 0.000000 0.00000000 1.583132 3.415148 1.0717436 4998 Predicted endonuclease (RecB family) L conserved hypothetical protein 1.506535 3.355479 1.1364279 182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J translation initiation factor aIF-2B alpha subunit 0.000000e+00 0 5.867113e-03 7.264386e-03 6.932295e-02 4.556272e-01 8.371319e-02 0 0 34 TRUE TRUE 40 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6587300 0.6128672 N 0.5492530 0.6245624 13773 129 182496 182497 1 106 Same + + 0.000000 0 0.000000 0.00000000 1.506535 3.355479 1.1364279 182 Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J translation initiation factor aIF-2B alpha subunit 1.669259 3.847976 1.0821173 - - - hypothetical protein 0.000000e+00 0 2.647922e-02 1.201363e-02 2.740225e-01 5.184435e-01 1.635808e-01 34 0 TRUE TRUE 41 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6837010 0.5892311 U 0.4686274 0.6162291 13773 129 182497 182498 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.669259 3.847976 1.0821173 - - - hypothetical protein 1.540553 3.353935 1.0946437 144 tRNA and rRNA cytosine-C5-methylases J RNA binding protein (fmu, PCNA P120 homolog), probable 0.000000e+00 0 1.656540e-02 1.942495e-02 1.475076e-01 6.803203e-01 5.479120e-02 0 5 TRUE TRUE 42 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7461327 0.6224019 U 0.4686274 0.6162291 13773 129 182498 182499 1 -16 Convergent + - 0.000000 0 0.000000 0.00000000 1.540553 3.353935 1.0946437 144 tRNA and rRNA cytosine-C5-methylases J RNA binding protein (fmu, PCNA P120 homolog), probable 1.432058 2.898941 0.9247452 - - - hypothetical protein 0.000000e+00 0 1.177120e-02 -1.723931e-03 -1.865737e-02 -6.484475e-02 6.506038e-01 5 0 TRUE TRUE 43 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5026348 0.4703906 U 0.4686274 0.6162291 13773 129 182499 182500 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.432058 2.898941 0.9247452 - - - hypothetical protein 1.512351 3.304625 1.0925300 2078 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 6.447011e-03 -1.178640e-03 1.544381e-02 -5.233451e-02 4.468353e-01 0 14 FALSE TRUE 42 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5061378 0.5044629 U 0.4686274 0.6162291 13773 129 182500 182501 1 106 Convergent + - 0.000000 0 0.000000 0.00000000 1.512351 3.304625 1.0925300 2078 Uncharacterized conserved protein S conserved hypothetical protein 1.533888 3.466014 1.1172152 - - - hypothetical protein 0.000000e+00 0 4.638368e-04 5.028723e-03 8.738081e-02 4.000485e-01 1.307626e-02 14 0 TRUE TRUE 43 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6357198 0.6414085 U 0.4686274 0.6162291 13773 129 182501 182502 1 139 Same - - 0.000000 0 0.000000 0.00000000 1.533888 3.466014 1.1172152 - - - hypothetical protein 1.641382 3.655480 1.0989031 - - - hypothetical protein 0.000000e+00 0 1.155511e-02 1.567317e-02 2.783765e-01 6.385901e-01 5.300950e-02 0 0 FALSE TRUE 42 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7331597 0.6228520 U 0.4686274 0.6162291 13773 129 182502 182503 1 65 Same - - 0.000000 0 0.000000 0.00000000 1.641382 3.655480 1.0989031 - - - hypothetical protein 1.495231 3.513274 1.1314811 1030 Membrane-bound serine protease (ClpP class) O conserved protein (nfeD homolog) 0.000000e+00 0 2.136035e-02 8.328715e-03 3.133346e-02 4.389422e-01 1.995065e-01 0 13 FALSE TRUE 41 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6517905 0.5802713 U 0.4686274 0.6162291 13773 129 182503 182504 1 -3 Same - - 21.836226 0 31.632499 31.63249937 1.495231 3.513274 1.1314811 1030 Membrane-bound serine protease (ClpP class) O conserved protein (nfeD homolog) 1.543997 3.438770 1.1166546 330 Membrane protease subunits, stomatin/prohibitin homologs O conserved protein (band 7 homolog) 1.631922e-01 13 2.378192e-03 4.059572e-03 8.510082e-02 3.454570e-01 6.259597e-02 O 13 20 FALSE TRUE 40 TRUE 2.3091900 1.9849804 0.5480306 2.3866357 0.7781369 1.1036584 0.6111945 0.6196253 Y 1.4497162 0.9293123 13773 129 182504 182505 1 594 Divergent - + 0.000000 0 0.000000 0.00000000 1.543997 3.438770 1.1166546 330 Membrane protease subunits, stomatin/prohibitin homologs O conserved protein (band 7 homolog) 1.368305 2.798821 0.9631346 - - - hypothetical protein 0.000000e+00 0 3.086772e-02 -7.694288e-03 -7.347221e-02 -4.903261e-01 1.963870e+00 20 0 FALSE TRUE 39 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4064110 0.4085563 U 0.4686274 0.6162291 13773 129 182505 182506 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.368305 2.798821 0.9631346 - - - hypothetical protein 1.637768 3.727488 1.1127721 1527 Archaeal/vacuolar-type H+-ATPase subunit C C H+-transporting ATP synthase subunit C (atpC) 0.000000e+00 0 7.261019e-02 -1.548547e-02 -8.964286e-02 -6.209415e-01 2.543327e+00 0 2 TRUE TRUE 40 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3924147 0.4031382 U 0.4686274 0.6162291 13773 129 182506 182507 1 2 Convergent + - 0.000000 0 0.000000 0.00000000 1.637768 3.727488 1.1127721 1527 Archaeal/vacuolar-type H+-ATPase subunit C C H+-transporting ATP synthase subunit C (atpC) 1.650310 3.966760 1.1578150 - - - H+-transporting ATP synthase subunit C (atpC) 0.000000e+00 0 1.572990e-04 3.707319e-02 4.664794e-01 8.580282e-01 1.908342e-04 2 0 TRUE TRUE 41 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7960501 0.6545960 U 0.4686274 0.6162291 13773 129 182507 182508 1 15 Same - - 0.000000 0 0.000000 0.00000000 1.650310 3.966760 1.1578150 - - - H+-transporting ATP synthase subunit C (atpC) 1.576964 3.268963 1.0634920 - - - hypothetical protein 0.000000e+00 0 5.379636e-03 2.497821e-02 2.523499e-01 7.656362e-01 1.272758e-02 0 0 FALSE TRUE 40 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7721850 0.6416331 U 0.4686274 0.6162291 13773 129 182508 182509 1 219 Same - - 0.000000 0 0.000000 0.00000000 1.576964 3.268963 1.0634920 - - - hypothetical protein 1.450868 3.187342 1.0537514 1394 Archaeal/vacuolar-type H+-ATPase subunit D C H+-transporting ATP synthase subunit D (atpD) 0.000000e+00 0 1.590013e-02 -6.588848e-05 -2.007518e-02 7.555620e-02 5.304489e-01 0 18 FALSE TRUE 39 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178581 0.4873963 U 0.4686274 0.6162291 13773 129 182509 182510 1 48 Divergent - + 0.000000 0 0.000000 -0.89864515 1.450868 3.187342 1.0537514 1394 Archaeal/vacuolar-type H+-ATPase subunit D C H+-transporting ATP synthase subunit D (atpD) 1.499951 3.312732 1.1080027 1161 Predicted GTPases R GTP binding protein, conjectural -1.549428e-02 18 2.409089e-03 -2.547879e-05 2.642688e-02 4.678972e-02 1.730254e-01 18 26 FALSE TRUE 38 FALSE 0.4469764 0.2154835 0.5480306 0.4469764 0.7781393 0.5247282 0.5186622 0.5869263 U 0.4686274 0.5304396 13773 129 182510 182511 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.499951 3.312732 1.1080027 1161 Predicted GTPases R GTP binding protein, conjectural 1.491585 3.601643 1.1213096 - - - hypothetical protein 0.000000e+00 0 6.998809e-05 1.951628e-03 4.167116e-02 2.292696e-01 3.225333e-03 26 0 TRUE TRUE 39 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5617339 0.6482245 U 0.4686274 0.6162291 13773 129 182511 182512 1 102 Convergent + - 0.000000 0 0.000000 0.00000000 1.491585 3.601643 1.1213096 - - - hypothetical protein 1.419527 3.087241 1.0290229 - - - hypothetical protein 0.000000e+00 0 5.192283e-03 -1.280739e-03 4.239303e-03 -1.007817e-01 4.550812e-01 0 0 TRUE TRUE 40 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4909197 0.5028383 U 0.4686274 0.6162291 13773 129 182512 182513 1 119 Divergent - + 0.000000 0 0.000000 0.00000000 1.419527 3.087241 1.0290229 - - - hypothetical protein 1.485878 3.193664 1.0945603 492 Thioredoxin reductase O hypothetical protein 0.000000e+00 0 4.402370e-03 -1.098877e-03 8.330621e-03 -9.255458e-02 4.067366e-01 0 0 FALSE TRUE 39 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4946359 0.5111403 U 0.4686274 0.6162291 13773 129 182513 182514 1 -18 Convergent + - 0.000000 0 0.000000 0.00000000 1.485878 3.193664 1.0945603 492 Thioredoxin reductase O hypothetical protein 1.493811 3.226773 1.0691591 1109 Phosphomannomutase G phosphomannomutase (pmm) 0.000000e+00 0 6.293533e-05 1.462771e-03 3.939013e-02 1.921064e-01 2.412521e-03 0 0 66 TRUE TRUE 40 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5469422 0.6495169 N 0.5492530 0.6245624 13773 129 182514 182515 1 114 Divergent - + 0.000000 0 0.000000 -1.06948049 1.493811 3.226773 1.0691591 1109 Phosphomannomutase G phosphomannomutase (pmm) 1.497458 3.330861 1.1050919 1415 Uncharacterized conserved protein S conserved hypothetical protein 2.790876e-04 11 1.330369e-05 1.953996e-03 4.440395e-02 2.273259e-01 7.215181e-04 66 11 FALSE TRUE 39 FALSE 0.4469764 0.2084843 0.5480306 0.4469764 0.7764261 0.4463331 0.5606037 0.6523872 U 0.4686274 0.5282179 13773 129 182515 182516 1 2 Convergent + - 0.000000 0 0.000000 -0.97359713 1.497458 3.330861 1.1050919 1415 Uncharacterized conserved protein S conserved hypothetical protein 1.644183 3.489635 1.0417960 284 Orotidine-5'-phosphate decarboxylase F orotidine-5'-monophosphate decarboxylase (pyrF) 9.712865e-02 11 2.152816e-02 8.880942e-03 2.135758e-01 4.554046e-01 1.920363e-01 11 23 TRUE TRUE 40 FALSE 0.4469764 0.2120169 0.5480306 0.4469764 0.7764261 1.0036732 0.6583952 0.5824114 U 0.4686274 0.5293394 13773 129 182516 182517 1 42 Divergent - + 2.662588 0 2.662588 -2.16516801 1.644183 3.489635 1.0417960 284 Orotidine-5'-phosphate decarboxylase F orotidine-5'-monophosphate decarboxylase (pyrF) 1.513341 3.258647 1.0469394 540 Aspartate carbamoyltransferase, catalytic chain F aspartate carbamoyltransferase catalytic subunit (pyrB) 5.494118e-02 23 1.711950e-02 1.194308e-02 7.573665e-02 5.409266e-01 1.198021e-01 F 23 64 FALSE TRUE 39 FALSE 2.9244472 0.1942280 0.5480306 2.9399224 0.7771174 0.8695312 0.6930913 0.6010459 Y 1.4497162 0.5543498 13773 129 182517 182518 1 -3 Same + + 0.000000 0 0.000000 -4.10362902 1.513341 3.258647 1.0469394 540 Aspartate carbamoyltransferase, catalytic chain F aspartate carbamoyltransferase catalytic subunit (pyrB) 1.540778 3.284618 1.0893749 456 Acetyltransferases R N-acyltransferase 3.779153e-03 22 7.527863e-04 5.537309e-03 9.602588e-02 4.179887e-01 1.824469e-02 64 22 TRUE TRUE 40 TRUE 0.4469764 0.1847245 0.5480306 0.4469764 0.7773546 0.5329002 0.6425199 0.6385209 U 0.4686274 0.5206679 13773 129 182518 182519 1 44 Same + + 0.000000 0 0.000000 0.00000000 1.540778 3.284618 1.0893749 456 Acetyltransferases R N-acyltransferase 1.437661 3.416257 1.1756233 2064 Flp pilus assembly protein TadC NU hypothetical protein 0.000000e+00 0 1.063328e-02 -1.227466e-03 -1.342540e-02 -2.918762e-02 5.749434e-01 22 0 TRUE TRUE 41 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5124020 0.4806166 U 0.4686274 0.6162291 13773 129 182519 182520 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.437661 3.416257 1.1756233 2064 Flp pilus assembly protein TadC NU hypothetical protein 1.455918 3.138264 1.0758581 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU conserved protein (possible type II secretion, gsp) 0.000000e+00 0 3.333421e-04 -6.214394e-05 1.958420e-02 -5.681440e-03 3.252722e-02 0 0 TRUE TRUE 42 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195653 0.6313366 U 0.4686274 0.6162291 13773 129 182520 182521 1 187 Same + + 0.000000 0 0.000000 0.00000000 1.455918 3.138264 1.0758581 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU conserved protein (possible type II secretion, gsp) 1.524230 3.523480 1.1428227 - - - hypothetical protein 0.000000e+00 0 4.666486e-03 3.296167e-04 3.801236e-02 8.972387e-02 2.526933e-01 0 0 TRUE TRUE 43 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178025 0.5615344 U 0.4686274 0.6162291 13773 129 182521 182522 1 34 Same + + 0.000000 0 0.000000 0.00000000 1.524230 3.523480 1.1428227 - - - hypothetical protein 1.487196 3.289940 1.1119503 343 Queuine/archaeosine tRNA-ribosyltransferase J queuine tRNA-ribosyltransferase 0.000000e+00 0 1.371477e-03 2.607831e-03 4.101187e-02 2.741015e-01 4.650759e-02 0 18 TRUE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5820979 0.6254296 U 0.4686274 0.6162291 13773 129 182522 182523 1 61 Convergent + - 2.662588 0 2.662588 2.52905643 1.487196 3.289940 1.1119503 343 Queuine/archaeosine tRNA-ribosyltransferase J queuine tRNA-ribosyltransferase 1.451376 3.120207 1.0852209 1938 Archaeal enzymes of ATP-grasp superfamily R conserved hypothetical protein 3.939979e-02 2 1.283124e-03 -6.122688e-07 1.747514e-02 4.060763e-02 1.099205e-01 18 2 TRUE TRUE 45 FALSE 2.9244472 1.6915159 0.5480306 2.9399224 0.6838149 0.8036459 0.5182413 0.6030494 U 0.4686274 0.8449322 13773 129 182523 182524 1 -3 Same - - 2.662588 0 2.662588 2.52905643 1.451376 3.120207 1.0852209 1938 Archaeal enzymes of ATP-grasp superfamily R conserved hypothetical protein 1.498892 3.209235 1.0064163 1675 Transcription initiation factor IIE, alpha subunit K conserved hypothetical protein 7.264158e-02 2 2.257823e-03 -8.122765e-07 2.645783e-02 4.761902e-02 1.642022e-01 2 6 FALSE TRUE 44 TRUE 2.9244472 1.6915159 0.5480306 2.9399224 0.6838149 0.9255497 0.5187029 0.5889325 U 0.4686274 0.8449322 13773 129 182524 182525 1 71 Same - - 2.079442 0 2.079442 1.87710112 1.498892 3.209235 1.0064163 1675 Transcription initiation factor IIE, alpha subunit K conserved hypothetical protein 1.485916 3.294559 1.1002488 2262 GTPases R conserved protein (possible hflX) 1.751301e-02 6 1.683775e-04 1.639844e-03 3.720832e-02 2.081412e-01 7.126832e-03 6 16 FALSE TRUE 43 TRUE 2.9335626 1.6493044 0.5480306 2.9479804 0.7537284 0.6569779 0.5531281 0.6443475 U 0.4686274 0.8376004 13773 129 182525 182526 1 -10 Same - - 5.689684 0 5.689684 5.46932462 1.485916 3.294559 1.1002488 2262 GTPases R conserved protein (possible hflX) 1.560335 3.393884 1.0718031 1813 Predicted transcription factor, homolog of eukaryotic MBF1 K conserved helix-turn-helix protein 3.156801e-02 10 5.538119e-03 3.761049e-03 9.182596e-02 3.243427e-01 1.323329e-01 16 10 FALSE TRUE 42 TRUE 2.7798012 1.7814095 0.5480306 2.8373132 0.7739415 0.7450579 0.6018359 0.5978214 U 0.4686274 0.8615068 13773 129 182526 182527 1 9 Divergent - + 0.000000 0 0.000000 -0.26296505 1.560335 3.393884 1.0718031 1813 Predicted transcription factor, homolog of eukaryotic MBF1 K conserved helix-turn-helix protein 1.537354 3.247715 1.0802860 1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit O conserved protein with predicted RNA binding PUA domain 8.710900e-02 3 5.281137e-04 9.364786e-03 1.188589e-01 5.487496e-01 5.772734e-03 0 10 3 FALSE TRUE 41 FALSE 0.4469764 0.2618532 0.5480306 0.4469764 0.7136133 0.9694943 0.6984841 0.6458271 N 0.5492530 0.5538839 13773 129 182527 182528 1 231 Convergent + - 0.000000 0 0.000000 0.00000000 1.537354 3.247715 1.0802860 1370 Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit O conserved protein with predicted RNA binding PUA domain 1.440953 3.135697 1.0550906 1676 tRNA splicing endonuclease J hypothetical protein 0.000000e+00 0 9.293125e-03 -8.974024e-04 -8.243501e-03 -2.160431e-03 4.996092e-01 0 3 0 TRUE TRUE 42 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199370 0.4925758 N 0.5492530 0.6245624 13773 129 182528 182529 1 209 Divergent - + 0.000000 0 0.000000 0.00000000 1.440953 3.135697 1.0550906 1676 tRNA splicing endonuclease J hypothetical protein 1.515501 3.360396 1.0818766 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 0.000000e+00 0 5.557444e-03 -6.692698e-04 2.307281e-02 -1.830595e-03 3.592636e-01 0 0 7 FALSE TRUE 41 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199618 0.5214465 N 0.5492530 0.6245624 13773 129 182529 182530 1 218 Same + + 0.000000 0 0.000000 -0.19540680 1.515501 3.360396 1.0818766 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 1.552381 3.931696 1.2241389 2095 Multiple antibiotic transporter U conserved hypothetical protein 2.005552e-02 6 1.360107e-03 6.474221e-03 1.118984e-01 4.471227e-01 2.355978e-02 0 7 6 TRUE TRUE 42 TRUE 0.4469764 0.2725548 0.5480306 0.4469764 0.7537284 0.6803870 0.6544113 0.6360567 N 0.5492530 0.5572505 13773 129 182530 182531 1 13 Same + + 0.000000 0 0.000000 -0.19540680 1.552381 3.931696 1.2241389 2095 Multiple antibiotic transporter U conserved hypothetical protein 1.503811 3.366408 1.1282142 489 ATPases involved in chromosome partitioning D conserved protein (possible ATP binding) 1.391474e-02 6 2.359009e-03 5.293667e-03 6.371106e-02 3.976342e-01 4.817739e-02 0 6 9 TRUE TRUE 43 TRUE 0.4469764 0.2725548 0.5480306 0.4469764 0.7537284 0.6317129 0.6332952 0.6245582 N 0.5492530 0.5572505 13773 129 182531 182532 1 -6 Convergent + - 0.000000 0 0.000000 -0.13353139 1.503811 3.366408 1.1282142 489 ATPases involved in chromosome partitioning D conserved protein (possible ATP binding) 1.422680 3.096117 1.0720129 295 Cytidine deaminase F cytidine deaminase 3.365329e-02 9 6.582377e-03 -1.505107e-03 -1.744595e-03 -1.045977e-01 5.293316e-01 0 9 32 TRUE TRUE 44 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.7702221 0.7635181 0.4897711 0.4876243 N 0.5492530 0.5604716 13773 129 182532 182533 1 38 Divergent - + 0.000000 0 0.000000 0.00000000 1.422680 3.096117 1.0720129 295 Cytidine deaminase F cytidine deaminase 1.531106 3.305982 1.0607563 - - - hypothetical protein 0.000000e+00 0 1.175618e-02 -2.288808e-03 8.018948e-03 -1.351748e-01 7.789451e-01 32 0 FALSE TRUE 43 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4807639 0.4575852 U 0.4686274 0.6162291 13773 129 182533 182534 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.531106 3.305982 1.0607563 - - - hypothetical protein 1.550767 3.563190 1.1586727 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 0.000000e+00 0 3.865655e-04 7.921371e-03 1.222984e-01 5.101928e-01 3.492148e-03 0 36 TRUE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6774964 0.6477695 U 0.4686274 0.6162291 13773 129 182534 182535 1 -11 Convergent + - 0.000000 0 0.000000 -7.02201546 1.550767 3.563190 1.1586727 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 1.491213 3.161209 1.0556459 112 Glycine/serine hydroxymethyltransferase E serine hydroxymethyltransferase 1.970137e-02 36 3.546621e-03 3.957119e-03 4.595413e-02 3.336535e-01 8.775781e-02 36 68 TRUE TRUE 45 FALSE 0.4469764 0.1801076 0.5480306 0.4469764 0.7743490 0.6747016 0.6055310 0.6119106 U 0.4686274 0.5191996 13773 129 182535 182536 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.491213 3.161209 1.0556459 112 Glycine/serine hydroxymethyltransferase E serine hydroxymethyltransferase 1.480207 3.215264 1.0717304 315 Molybdenum cofactor biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaC) 0.000000e+00 0 1.211305e-04 1.147409e-03 3.223519e-02 1.640750e-01 6.743397e-03 0 68 0 FALSE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5360872 0.6447284 N 0.5492530 0.6245624 13773 129 182536 182537 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.480207 3.215264 1.0717304 315 Molybdenum cofactor biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaC) 1.585448 3.414269 0.9758900 - - - hypothetical protein 0.000000e+00 0 1.107550e-02 3.862726e-03 1.094300e-01 3.065168e-01 2.220485e-01 0 0 FALSE TRUE 43 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5943777 0.5735582 U 0.4686274 0.6162291 13773 129 182537 182538 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.585448 3.414269 0.9758900 - - - hypothetical protein 1.477482 3.238811 1.1013507 1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases C conserved protein (possible oxidoreductase) 0.000000e+00 0 1.165662e-02 3.497345e-03 1.772141e-02 2.865964e-01 2.450364e-01 0 32 FALSE TRUE 42 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5874146 0.5644275 U 0.4686274 0.6162291 13773 129 182538 182539 1 0 Same - - 0.000000 0 0.000000 -1.48359756 1.477482 3.238811 1.1013507 1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases C conserved protein (possible oxidoreductase) 1.587510 3.318279 1.0406920 90 Ribosomal protein L2 J ribosomal protein L2 6.836120e-02 17 1.210628e-02 3.551159e-03 1.075823e-01 2.889607e-01 2.519223e-01 0 32 17 FALSE TRUE 41 TRUE 0.4469764 0.2022731 0.5480306 0.4469764 0.7782882 0.9080867 0.5890110 0.5619549 N 0.5492530 0.5350582 13773 129 182539 182540 1 131 Divergent - + 0.000000 0 0.000000 -0.90561490 1.587510 3.318279 1.0406920 90 Ribosomal protein L2 J ribosomal protein L2 1.583317 3.336390 1.0640766 1383 Ribosomal protein S17E J ribosomal protein S17 2.403925e-01 10 1.758774e-05 1.795712e-02 2.278427e-01 7.055564e-01 7.126832e-05 J 17 10 FALSE TRUE 40 FALSE 0.4469764 0.2140058 0.5480306 0.4469764 0.7739415 1.1774989 0.7554227 0.6552829 Y 1.4497162 0.6342789 13773 129 182540 182541 1 3 Same + + 0.000000 0 0.000000 -0.72495596 1.583317 3.336390 1.0640766 1383 Ribosomal protein S17E J ribosomal protein S17 1.435934 3.103154 1.0567906 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O FKBP-type peptidyl-prolyl cis-trans isomerases 2.081423e-01 10 2.172168e-02 -2.039419e-03 -4.669814e-02 -4.361621e-02 7.884568e-01 0 10 10 TRUE TRUE 41 TRUE 0.4469764 0.2231634 0.5480306 0.4469764 0.7739415 1.1467808 0.5080803 0.4570748 N 0.5492530 0.5416732 13773 129 182541 182542 1 36 Same + + 2.833213 0 2.833213 2.48134488 1.435934 3.103154 1.0567906 1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 O FKBP-type peptidyl-prolyl cis-trans isomerases 1.453995 3.165476 1.0281217 638 20S proteasome, alpha and beta subunits O proteasome beta subunit 1.313252e-01 8 3.262058e-04 -4.022592e-05 1.967765e-02 -6.248053e-03 2.955338e-02 O 10 8 TRUE TRUE 42 TRUE 2.9141387 1.6886759 0.5480306 2.9300754 0.7652913 1.0689402 0.5194678 0.6332836 Y 1.4497162 0.8931801 13773 129 182542 182543 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.453995 3.165476 1.0281217 638 20S proteasome, alpha and beta subunits O proteasome beta subunit 1.534006 3.756878 1.1244229 - - - hypothetical protein 0.000000e+00 0 6.401818e-03 2.149677e-04 4.056606e-02 8.315423e-02 3.304264e-01 8 0 TRUE TRUE 43 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176981 0.5311515 U 0.4686274 0.6162291 13773 129 182543 182544 1 40 Same - - 0.000000 0 0.000000 0.00000000 1.534006 3.756878 1.1244229 - - - hypothetical protein 1.499482 3.647066 1.1301344 - - - hypothetical protein 0.000000e+00 0 1.191935e-03 3.972802e-03 5.572946e-02 3.507403e-01 3.593396e-02 0 0 FALSE TRUE 42 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6128399 0.6295510 U 0.4686274 0.6162291 13773 129 182544 182545 1 150 Same - - 0.000000 0 0.000000 0.00000000 1.499482 3.647066 1.1301344 - - - hypothetical protein 1.509771 2.970430 0.9679292 1051 ADP-ribose pyrophosphatase F mutT/nudix family protein 0.000000e+00 0 1.058597e-04 2.807336e-03 5.634367e-02 2.844678e-01 3.402032e-03 0 1 FALSE TRUE 41 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5861947 0.6479144 U 0.4686274 0.6162291 13773 129 182545 182546 1 -14 Divergent - + 0.000000 0 0.000000 0.00000000 1.509771 2.970430 0.9679292 1051 ADP-ribose pyrophosphatase F mutT/nudix family protein 1.565516 3.273674 1.0636836 - - - hypothetical protein 0.000000e+00 0 3.107506e-03 6.662249e-03 1.230546e-01 4.474532e-01 5.336348e-02 1 0 FALSE TRUE 40 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6547409 0.6227021 U 0.4686274 0.6162291 13773 129 182546 182547 1 135 Same + + 0.000000 0 0.000000 0.00000000 1.565516 3.273674 1.0636836 - - - hypothetical protein 1.465128 3.124450 1.0733994 148 Enolase G enolase 0.000000e+00 0 1.007778e-02 1.567449e-03 6.469158e-03 1.767867e-01 3.269066e-01 0 72 TRUE TRUE 41 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5409111 0.5320384 U 0.4686274 0.6162291 13773 129 182547 182548 1 31 Same + + 0.000000 0 0.000000 -0.24929257 1.465128 3.124450 1.0733994 148 Enolase G enolase 1.446528 3.075336 1.0341624 2005 N-terminal domain of molybdenum-binding protein R molybdenum-pterin-binding protein, conjectural 1.134242e-03 3 3.459264e-04 -6.681062e-05 1.953755e-02 1.076093e-02 3.035029e-02 72 3 TRUE TRUE 42 TRUE 0.4469764 0.2655387 0.5480306 0.4469764 0.7136133 0.4743646 0.5188347 0.6329638 U 0.4686274 0.5462885 13773 129 182548 182549 1 -15 Convergent + - 0.000000 0 0.000000 -0.24929257 1.446528 3.075336 1.0341624 2005 N-terminal domain of molybdenum-binding protein R molybdenum-pterin-binding protein, conjectural 1.453060 3.282593 1.0830607 2896 Molybdenum cofactor biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 1.979252e-02 3 4.266377e-05 -8.110820e-06 2.058983e-02 5.603104e-03 4.561173e-03 3 46 TRUE TRUE 43 FALSE 0.4469764 0.2655387 0.5480306 0.4469764 0.7136133 0.6769674 0.5194054 0.6466721 U 0.4686274 0.5462885 13773 129 182549 182550 1 417 Divergent - + 0.000000 0 0.000000 0.00000000 1.453060 3.282593 1.0830607 2896 Molybdenum cofactor biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 1.539114 3.490453 1.1355176 515 Serine/threonine protein kinase RTKL serine/threonine protein kinase, putative 1.328577e-02 1 7.405284e-03 1.462666e-04 4.198244e-02 8.217886e-02 3.519412e-01 46 1 FALSE TRUE 42 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.6266456 0.5177197 0.5245375 U 0.4686274 0.6162291 13773 129 182550 182551 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.539114 3.490453 1.1355176 515 Serine/threonine protein kinase RTKL serine/threonine protein kinase, putative 1.405822 3.066275 1.0521206 1716 FOG: FHA domain T conserved protein with Forkhead-associated (FHA) domain 0.000000e+00 0 1.776688e-02 -3.997559e-03 -4.027065e-02 -2.503462e-01 1.128193e+00 1 0 TRUE TRUE 43 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4519979 0.4315963 U 0.4686274 0.6162291 13773 129 182551 182552 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.405822 3.066275 1.0521206 1716 FOG: FHA domain T conserved protein with Forkhead-associated (FHA) domain 1.449734 3.148717 1.0133307 52 Ribosomal protein S2 J ribosomal protein S2 0.000000e+00 0 1.928317e-03 7.557962e-05 1.635451e-02 -2.871937e-02 1.886879e-01 0 0 24 TRUE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5124682 0.5831776 N 0.5492530 0.6245624 13773 129 182552 182553 1 0 Same + + 11.478023 0 19.747230 19.09335264 1.449734 3.148717 1.0133307 52 Ribosomal protein S2 J ribosomal protein S2 1.473521 3.146803 1.0158347 1355 Predicted dioxygenase R conserved hypothetical protein 1.080117e-01 14 5.657866e-04 -3.669888e-05 2.154505e-02 2.447390e-02 4.817739e-02 24 14 TRUE TRUE 45 TRUE 2.6221289 1.9090096 0.5480306 2.6004115 0.7782928 1.0391005 0.5173998 0.6245582 U 0.4686274 0.8818418 13773 129 182553 182554 1 -3 Convergent + - 0.000000 0 0.000000 -0.99153234 1.473521 3.146803 1.0158347 1355 Predicted dioxygenase R conserved hypothetical protein 1.478206 3.359414 1.1499565 469 Pyruvate kinase G pyruvate kinase 2.250070e-04 14 2.195637e-05 5.933237e-04 2.825738e-02 1.057457e-01 2.565660e-03 14 46 TRUE TRUE 46 FALSE 0.4469764 0.2110144 0.5480306 0.4469764 0.7782928 0.4447162 0.5193883 0.6491703 U 0.4686274 0.5290211 13773 129 182554 182555 1 70 Same - - 0.000000 0 0.000000 -1.22906110 1.478206 3.359414 1.1499565 469 Pyruvate kinase G pyruvate kinase 1.459370 3.097435 1.0818092 1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH d R mRNA 3'-end processing factor, conjectural 4.129487e-04 17 3.548021e-04 2.139007e-04 2.157447e-02 6.096563e-02 3.170203e-02 46 17 FALSE TRUE 45 TRUE 0.4469764 0.2054034 0.5480306 0.4469764 0.7782882 0.4535485 0.5184704 0.6317872 U 0.4686274 0.5272395 13773 129 182555 182556 1 43 Divergent - + 0.000000 0 0.000000 -1.59857000 1.459370 3.097435 1.0818092 1782 Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH d R mRNA 3'-end processing factor, conjectural 1.427379 2.958822 1.0306013 215 Cysteinyl-tRNA synthetase J cysteinyl-tRNA synthetase 1.026729e-02 17 1.023456e-03 -1.915691e-04 1.980068e-02 -2.529142e-02 1.019290e-01 17 67 FALSE TRUE 44 FALSE 0.4469764 0.2006892 0.5480306 0.4469764 0.7782882 0.6013653 0.5137307 0.6058668 U 0.4686274 0.5257421 13773 129 182556 182557 1 -15 Convergent + - 0.000000 0 0.000000 0.00000000 1.427379 2.958822 1.0306013 215 Cysteinyl-tRNA synthetase J cysteinyl-tRNA synthetase 1.534494 3.377874 1.1157814 - - - paREP1 0.000000e+00 0 1.147379e-02 -1.995616e-03 1.347746e-02 -1.015014e-01 7.088012e-01 67 0 TRUE TRUE 45 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4905758 0.4637726 U 0.4686274 0.6162291 13773 129 182557 182558 1 101 Same - - 0.000000 0 0.000000 0.00000000 1.534494 3.377874 1.1157814 - - - paREP1 1.493703 3.239560 1.0849401 - - - P. aerophilum family 1964 protein 0.000000e+00 0 1.663927e-03 3.516062e-03 4.885707e-02 3.210650e-01 5.515108e-02 0 0 FALSE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6000118 0.6221915 U 0.4686274 0.6162291 13773 129 182558 182559 1 38 Same - - 0.000000 0 0.000000 0.00000000 1.493703 3.239560 1.0849401 - - - P. aerophilum family 1964 protein 1.486127 3.329788 1.1688817 - - - hypothetical protein 0.000000e+00 0 5.740027e-05 1.469612e-03 3.643847e-02 1.925682e-01 1.913643e-03 0 0 FALSE TRUE 43 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5470988 0.6504429 U 0.4686274 0.6162291 13773 129 182559 182560 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.486127 3.329788 1.1688817 - - - hypothetical protein 1.441863 3.256038 1.1299402 - - - hypothetical protein 0.000000e+00 0 1.959297e-03 -3.310110e-04 1.403424e-02 2.563304e-03 1.692157e-01 0 0 FALSE TRUE 42 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197693 0.5878822 U 0.4686274 0.6162291 13773 129 182560 182561 1 42 Same + + 0.000000 0 0.000000 0.00000000 1.441863 3.256038 1.1299402 - - - hypothetical protein 1.391891 3.129297 1.1043846 - - - hypothetical protein 0.000000e+00 0 2.497164e-03 5.670409e-04 3.612801e-02 -2.973244e-03 2.404988e-01 0 0 TRUE TRUE 43 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198601 0.5658265 U 0.4686274 0.6162291 13773 129 182561 182562 1 60 Same + + 0.000000 0 0.000000 0.00000000 1.391891 3.129297 1.1043846 - - - hypothetical protein 1.510709 3.415478 1.0846840 2078 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.411768e-02 -3.529412e-03 -2.058505e-02 -2.742817e-01 1.103870e+00 0 0 TRUE TRUE 44 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4464598 0.4325133 U 0.4686274 0.6162291 13773 129 182562 182563 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.510709 3.415478 1.0846840 2078 Uncharacterized conserved protein S conserved hypothetical protein 1.503360 3.364273 1.0714091 5373 Predicted membrane protein S hypothetical protein 0.000000e+00 0 5.400358e-05 3.082532e-03 5.470273e-02 2.981890e-01 1.592641e-03 0 0 TRUE TRUE 45 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5913657 0.6508783 U 0.4686274 0.6162291 13773 129 182563 182564 1 -19 Same + + 0.000000 0 0.000000 0.00000000 1.503360 3.364273 1.0714091 5373 Predicted membrane protein S hypothetical protein 1.426583 3.117886 0.9977260 1437 Adenylate cyclase, class 2 (thermophilic) F adenylate cyclase 0.000000e+00 0 5.894842e-03 -1.289329e-03 3.673888e-04 -8.161813e-02 4.644480e-01 0 8 TRUE TRUE 46 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4973948 0.5005273 U 0.4686274 0.6162291 13773 129 182564 182565 1 8 Same + + 0.000000 0 0.000000 -0.64121939 1.426583 3.117886 0.9977260 1437 Adenylate cyclase, class 2 (thermophilic) F adenylate cyclase 1.363420 3.000304 1.0377123 1793 ATP-dependent DNA ligase L DNA ligase 1.009977e-01 8 3.989529e-03 2.182628e-03 6.434827e-02 1.093397e-01 3.027955e-01 0 8 23 TRUE TRUE 47 TRUE 0.4469764 0.2277940 0.5480306 0.4469764 0.7652913 1.0184367 0.5198242 0.5404711 N 0.5492530 0.5431375 13773 129 182565 182566 1 -12 Convergent + - 0.000000 0 0.000000 0.00000000 1.363420 3.000304 1.0377123 1793 ATP-dependent DNA ligase L DNA ligase 1.353158 2.858480 1.0113100 - - - hypothetical protein 0.000000e+00 0 1.053108e-04 8.642026e-03 1.266354e-01 5.364143e-01 3.053347e-03 23 0 TRUE TRUE 48 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6900526 0.6486369 U 0.4686274 0.6162291 13773 129 182566 182567 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.353158 2.858480 1.0113100 - - - hypothetical protein 1.481347 3.252315 1.1060134 524 Sugar kinases, ribokinase family G sugar kinase, possible phosphofructokinase 0.000000e+00 0 1.643252e-02 -2.942565e-03 -3.589558e-02 -2.860098e-01 1.291877e+00 0 48 FALSE TRUE 47 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4436539 0.4242983 U 0.4686274 0.6162291 13773 129 182567 182568 1 20 Same + + 0.000000 0 0.000000 0.00000000 1.481347 3.252315 1.1060134 524 Sugar kinases, ribokinase family G sugar kinase, possible phosphofructokinase 1.279916 2.668448 0.9278247 - - - conserved hypothetical protein 0.000000e+00 0 4.057463e-02 -5.136482e-03 3.307466e-02 -3.650882e-01 1.814117e+00 48 0 TRUE TRUE 48 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4247594 0.4105806 U 0.4686274 0.6162291 13773 129 182568 182569 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.279916 2.668448 0.9278247 - - - conserved hypothetical protein 1.506127 3.432370 1.1171862 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase 0.000000e+00 0 5.117175e-02 -9.385734e-03 -1.560676e-01 -5.252799e-01 2.285828e+00 0 0 TRUE TRUE 49 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4012022 0.4051863 U 0.4686274 0.6162291 13773 129 182569 182570 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.506127 3.432370 1.1171862 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase 1.433042 3.179839 1.0745698 - - - hypothetical protein 0.000000e+00 0 5.341497e-03 -1.004431e-03 2.240736e-03 -4.069362e-02 3.797889e-01 0 0 TRUE TRUE 50 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5089582 0.5171998 U 0.4686274 0.6162291 13773 129 182570 182571 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.433042 3.179839 1.0745698 - - - hypothetical protein 1.394041 2.996007 1.0562057 - - - hypothetical protein 0.000000e+00 0 1.521079e-03 1.052462e-03 4.054125e-02 3.509464e-02 1.531974e-01 0 0 TRUE TRUE 51 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175935 0.5924418 U 0.4686274 0.6162291 13773 129 182571 182572 1 -31 Convergent + - 0.000000 0 0.000000 0.00000000 1.394041 2.996007 1.0562057 - - - hypothetical protein 1.574368 3.557632 1.1554942 1585 Membrane protein implicated in regulation of membrane protease activity OU conserved hypothetical protein 0.000000e+00 0 3.251784e-02 -7.052861e-03 -3.167474e-02 -3.799532e-01 1.640680e+00 0 0 TRUE TRUE 52 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4228929 0.4136182 U 0.4686274 0.6162291 13773 129 182572 182573 1 27 Divergent - + 0.000000 0 0.000000 0.00000000 1.574368 3.557632 1.1554942 1585 Membrane protein implicated in regulation of membrane protease activity OU conserved hypothetical protein 1.422092 3.092617 1.0807382 1341 Predicted GTPase or GTP-binding protein R conserved hypothetical protein 0.000000e+00 0 2.318784e-02 -3.603226e-03 -5.761670e-02 -1.656046e-01 1.035615e+00 0 0 FALSE TRUE 51 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4735558 0.4363716 U 0.4686274 0.6162291 13773 129 182573 182574 1 464 Same + + 0.000000 0 0.000000 0.00000000 1.422092 3.092617 1.0807382 1341 Predicted GTPase or GTP-binding protein R conserved hypothetical protein 1.496691 3.264346 1.0897555 - - - paREP1 0.000000e+00 0 5.564931e-03 -1.327252e-03 8.249717e-03 -9.817653e-02 4.707455e-01 0 0 TRUE TRUE 52 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4921679 0.4989495 U 0.4686274 0.6162291 13773 129 182574 182575 1 153 Same + + 0.000000 0 0.000000 0.00000000 1.496691 3.264346 1.0897555 - - - paREP1 1.539562 3.271036 1.1252582 - - - paREP2a 0.000000e+00 0 1.837956e-03 3.993899e-03 8.196638e-02 3.430621e-01 5.195461e-02 0 0 TRUE TRUE 53 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6101043 0.6232413 U 0.4686274 0.6162291 13773 129 182575 182576 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.539562 3.271036 1.1252582 - - - paREP2a 1.520816 3.409530 1.1258872 - - - paREP2a 0.000000e+00 0 3.514403e-04 6.120955e-03 8.480304e-02 4.466898e-01 6.743397e-03 0 0 TRUE TRUE 54 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6540822 0.6447284 U 0.4686274 0.6162291 13773 129 182576 182577 1 589 Same + + 0.000000 0 0.000000 0.00000000 1.520816 3.409530 1.1258872 - - - paREP2a 1.447233 3.132004 1.1125610 - - - paREP2b 0.000000e+00 0 5.414354e-03 -2.887725e-04 5.166042e-03 3.569659e-02 3.269066e-01 0 0 TRUE TRUE 55 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176804 0.5320384 U 0.4686274 0.6162291 13773 129 182577 182578 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.447233 3.132004 1.1125610 - - - paREP2b 1.315118 3.082837 1.0683350 - - - paREP2b 0.000000e+00 0 1.745438e-02 5.668520e-04 7.448220e-02 -5.156175e-02 9.306400e-01 0 0 TRUE TRUE 56 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5063500 0.4448241 U 0.4686274 0.6162291 13773 129 182578 182579 1 281 Convergent + - 0.000000 0 0.000000 0.00000000 1.315118 3.082837 1.0683350 - - - paREP2b 1.520230 3.007831 0.9799636 - - - hypothetical protein 0.000000e+00 0 4.207099e-02 -9.380805e-03 -1.240723e-01 -5.650889e-01 2.341863e+00 0 0 TRUE TRUE 57 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3972970 0.4046271 U 0.4686274 0.6162291 13773 129 182579 182580 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.520230 3.007831 0.9799636 - - - hypothetical protein 1.514707 3.339650 1.1079437 1145 Ferredoxin C hypothetical protein 0.000000e+00 0 3.050757e-05 4.358386e-03 6.984352e-02 3.687647e-01 8.958605e-04 0 0 FALSE TRUE 56 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6195476 0.6519767 U 0.4686274 0.6162291 13773 129 182580 182581 1 13 Same - - 0.000000 0 0.000000 0.00000000 1.514707 3.339650 1.1079437 1145 Ferredoxin C hypothetical protein 1.376923 2.959327 1.0256184 727 Predicted Fe-S-cluster oxidoreductase R conserved hypothetical protein 0.000000e+00 0 1.898455e-02 -4.715022e-03 -3.048807e-02 -3.628535e-01 1.451812e+00 0 0 FALSE TRUE 55 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4253771 0.4183522 U 0.4686274 0.6162291 13773 129 182581 182582 1 391 Divergent - + 0.000000 0 0.000000 0.00000000 1.376923 2.959327 1.0256184 727 Predicted Fe-S-cluster oxidoreductase R conserved hypothetical protein 1.530738 3.089687 1.0322092 2163 Ribosomal protein L14E/L6E/L27E J ribosomal protein L14 0.000000e+00 0 2.365912e-02 -5.908840e-03 -4.644602e-02 -4.178456e-01 1.676260e+00 0 6 FALSE TRUE 54 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4156704 0.4127699 U 0.4686274 0.6162291 13773 129 182582 182583 1 -3 Same + + 0.000000 0 0.000000 -0.39438724 1.530738 3.089687 1.0322092 2163 Ribosomal protein L14E/L6E/L27E J ribosomal protein L14 1.553793 3.395572 1.0946606 130 Pseudouridine synthase J tRNA pseudouridine synthase B 5.817335e-03 6 5.315223e-04 8.124896e-03 1.263770e-01 5.157618e-01 5.428172e-03 J 6 36 TRUE TRUE 55 TRUE 0.4469764 0.2425956 0.5480306 0.4469764 0.7537284 0.5520185 0.6807626 0.6460943 Y 1.4497162 0.6426867 13773 129 182583 182584 1 73 Same + + 0.000000 0 0.000000 0.00000000 1.553793 3.395572 1.0946606 130 Pseudouridine synthase J tRNA pseudouridine synthase B 1.656478 3.372302 1.1238781 1888 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.054428e-02 2.100065e-02 3.464661e-01 7.089549e-01 3.308323e-02 36 0 TRUE TRUE 56 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7567634 0.6310514 U 0.4686274 0.6162291 13773 129 182584 182585 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.656478 3.372302 1.1238781 1888 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.410424 3.472098 1.1644774 1814 Uncharacterized membrane protein S conserved hypothetical protein 0.000000e+00 0 6.054233e-02 -8.402017e-03 -1.800501e-01 -2.914992e-01 1.559144e+00 0 0 TRUE TRUE 57 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4425799 0.4154925 U 0.4686274 0.6162291 13773 129 182585 182586 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.410424 3.472098 1.1644774 1814 Uncharacterized membrane protein S conserved hypothetical protein 1.507787 3.218375 1.0704351 - - - hypothetical protein 0.000000e+00 0 9.479384e-03 -2.310362e-03 -2.461786e-03 -1.727049e-01 7.507564e-01 0 0 TRUE TRUE 58 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4722396 0.4596276 U 0.4686274 0.6162291 13773 129 182586 182587 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.507787 3.218375 1.0704351 - - - hypothetical protein 1.386871 3.012888 1.0581280 673 Predicted dehydrogenases and related proteins R conserved NAD/P oxidoreductase 0.000000e+00 0 1.462047e-02 -3.638603e-03 -1.931011e-02 -2.959438e-01 1.184305e+00 0 19 TRUE TRUE 59 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4416760 0.4290592 U 0.4686274 0.6162291 13773 129 182587 182588 1 60 Same + + 0.000000 0 0.000000 0.00000000 1.386871 3.012888 1.0581280 673 Predicted dehydrogenases and related proteins R conserved NAD/P oxidoreductase 1.409456 3.117503 1.0507727 - - - hypothetical protein 0.000000e+00 0 5.100510e-04 2.705847e-03 4.626948e-02 1.684100e-01 4.683919e-02 19 0 TRUE TRUE 60 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5381862 0.6252488 U 0.4686274 0.6162291 13773 129 182588 182589 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.409456 3.117503 1.0507727 - - - hypothetical protein 1.465711 3.583837 1.1803597 1266 Predicted metal-dependent membrane protease R conserved hypothetical protein 0.000000e+00 0 3.164689e-03 -6.004734e-04 9.771131e-03 -7.134371e-02 2.935760e-01 0 1 TRUE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5011836 0.5445363 U 0.4686274 0.6162291 13773 129 182589 182590 1 29 Divergent - + 0.000000 0 0.000000 0.00000000 1.465711 3.583837 1.1803597 1266 Predicted metal-dependent membrane protease R conserved hypothetical protein 1.452901 3.035021 1.0316017 - - - hypothetical protein 0.000000e+00 0 1.640975e-04 2.159730e-05 2.047535e-02 2.597465e-02 1.221339e-02 1 0 FALSE TRUE 60 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173871 0.6419378 U 0.4686274 0.6162291 13773 129 182590 182591 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.452901 3.035021 1.0316017 - - - hypothetical protein 1.425474 3.133749 1.0918115 1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA R competence damage protein, conjectural 0.000000e+00 0 7.522447e-04 -3.909473e-05 2.198080e-02 -1.926012e-02 7.976398e-02 0 13 TRUE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5156999 0.6145887 U 0.4686274 0.6162291 13773 129 182591 182592 1 11 Same - - 0.000000 0 0.000000 -0.38282396 1.425474 3.133749 1.0918115 1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA R competence damage protein, conjectural 1.470485 3.684082 1.2323363 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 3.459085e-02 8 2.026005e-03 -4.948518e-04 1.417146e-02 -4.596748e-02 1.954142e-01 13 8 FALSE TRUE 60 TRUE 0.4469764 0.2444483 0.5480306 0.4469764 0.7652913 0.7675504 0.5076707 0.5811598 U 0.4686274 0.5396202 13773 129 182592 182593 1 41 Divergent - + 0.000000 0 0.000000 -0.43209501 1.470485 3.684082 1.2323363 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.446824 3.145806 1.0665260 1225 Peroxiredoxin O antioxidant protein, putative 1.896643e-02 8 5.598349e-04 -8.722161e-05 1.884516e-02 1.454934e-02 4.919340e-02 8 18 FALSE TRUE 59 FALSE 0.4469764 0.2392413 0.5480306 0.4469764 0.7652913 0.6713241 0.5181939 0.6240491 U 0.4686274 0.5379716 13773 129 182593 182594 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.446824 3.145806 1.0665260 1225 Peroxiredoxin O antioxidant protein, putative 1.488847 3.313913 1.1255926 - - - hypothetical protein 0.000000e+00 0 1.765856e-03 -1.711029e-04 2.224648e-02 2.300259e-02 1.454869e-01 18 0 TRUE TRUE 60 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174613 0.5941308 U 0.4686274 0.6162291 13773 129 182594 182595 1 -31 Convergent + - 0.000000 0 0.000000 0.00000000 1.488847 3.313913 1.1255926 - - - hypothetical protein 1.408977 3.268247 1.1057475 2044 Predicted peroxiredoxins R conserved hypothetical protein 0.000000e+00 0 6.379114e-03 -1.588623e-03 3.169488e-03 -1.403491e-01 5.737801e-01 0 2 TRUE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4795323 0.4809145 U 0.4686274 0.6162291 13773 129 182595 182596 1 52 Same - - 0.000000 0 0.000000 -0.13150953 1.408977 3.268247 1.1057475 2044 Predicted peroxiredoxins R conserved hypothetical protein 1.451336 3.243689 1.1011245 177 Predicted EndoIII-related endonuclease L DNA-(apurinic or apyrimidinic site) lyase (endonuclease III, PaNth) 6.687249e-03 2 1.794260e-03 2.415338e-06 1.619714e-02 -3.049990e-02 1.743046e-01 2 58 FALSE TRUE 60 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.5679838 0.5118739 0.5863631 U 0.4686274 0.5537552 13773 129 182596 182597 1 46 Divergent - + 0.000000 0 0.000000 -0.07232066 1.451336 3.243689 1.1011245 177 Predicted EndoIII-related endonuclease L DNA-(apurinic or apyrimidinic site) lyase (endonuclease III, PaNth) 1.360445 2.857612 1.0272008 - - - conserved hypothetical protein 3.317640e-03 1 8.261101e-03 5.178962e-06 4.180367e-02 -6.802709e-02 6.642938e-01 58 1 FALSE TRUE 59 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.5238969 0.5015123 0.4695664 U 0.4686274 0.5573725 13773 129 182597 182598 1 45 Same + + 0.000000 0 0.000000 0.00000000 1.360445 2.857612 1.0272008 - - - conserved hypothetical protein 1.437552 3.195152 1.0902979 - - - hypothetical protein 0.000000e+00 0 5.945421e-03 1.258804e-03 1.493704e-02 2.986555e-02 4.613151e-01 1 0 TRUE TRUE 60 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173858 0.5017230 U 0.4686274 0.6162291 13773 129 182598 182599 1 374 Same + + 0.000000 0 0.000000 0.00000000 1.437552 3.195152 1.0902979 - - - hypothetical protein 1.455734 3.115681 1.0798994 2317 Zn-dependent carboxypeptidase E thermostable carboxypeptidase 0.000000e+00 0 3.305775e-04 -6.008103e-05 1.959656e-02 -5.661414e-03 3.170203e-02 0 17 TRUE TRUE 61 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195879 0.6317872 U 0.4686274 0.6162291 13773 129 182599 182600 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.455734 3.115681 1.0798994 2317 Zn-dependent carboxypeptidase E thermostable carboxypeptidase 1.469651 3.264140 1.1324701 - - - hypothetical protein 0.000000e+00 0 1.936848e-04 7.925391e-05 2.246304e-02 3.679919e-02 1.762801e-02 17 0 TRUE TRUE 62 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178299 0.6389823 U 0.4686274 0.6162291 13773 129 182600 182601 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.469651 3.264140 1.1324701 - - - hypothetical protein 1.290259 2.920433 1.0092300 1019 Predicted nucleotidyltransferase R conserved protein (possible cytidylyltransferase) 0.000000e+00 0 3.218129e-02 -2.941957e-03 5.142884e-02 -2.594550e-01 1.519156e+00 0 8 FALSE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4506836 0.4165262 U 0.4686274 0.6162291 13773 129 182601 182602 1 -29 Convergent + - 0.000000 0 0.000000 0.00000000 1.290259 2.920433 1.0092300 1019 Predicted nucleotidyltransferase R conserved protein (possible cytidylyltransferase) 1.427958 3.110262 1.0780717 4882 Predicted aminopeptidase, Iap family R conserved hypothetical protein 1.557260e-03 1 1.896106e-02 3.776072e-03 3.473306e-04 1.345322e-01 6.781263e-01 8 1 TRUE TRUE 62 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.5263238 0.4669420 U 0.4686274 0.6162291 13773 129 182602 182603 1 17 Same - - 0.000000 0 0.000000 0.00000000 1.427958 3.110262 1.0780717 4882 Predicted aminopeptidase, Iap family R conserved hypothetical protein 1.395690 3.176819 1.0359613 - - - hypothetical protein 0.000000e+00 0 1.041274e-03 1.305373e-03 4.248555e-02 6.453258e-02 1.038986e-01 1 0 FALSE TRUE 61 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183075 0.6047112 U 0.4686274 0.6162291 13773 129 182603 182604 1 120 Divergent - + 0.000000 0 0.000000 0.00000000 1.395690 3.176819 1.0359613 - - - hypothetical protein 1.367194 3.001789 1.0632445 1254 Acylphosphatases C conserved hypothetical protein 0.000000e+00 0 8.120184e-04 4.690162e-03 8.570051e-02 3.155714e-01 4.885355e-02 0 0 FALSE TRUE 60 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5982030 0.6242586 U 0.4686274 0.6162291 13773 129 182604 182605 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.367194 3.001789 1.0632445 1254 Acylphosphatases C conserved hypothetical protein 1.499050 3.257809 1.1115424 123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein BQ hypothetical protein 0.000000e+00 0 1.738609e-02 -4.012693e-03 -3.841593e-02 -3.423059e-01 1.402307e+00 0 0 TRUE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4290352 0.4195990 U 0.4686274 0.6162291 13773 129 182605 182606 1 105 Divergent - + 0.000000 0 0.000000 0.00000000 1.499050 3.257809 1.1115424 123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein BQ hypothetical protein 1.512006 3.262629 1.0978213 77 Prephenate dehydratase E chorismate mutase/prephenate dehydratase (P-protein) 0.000000e+00 0 1.678447e-04 2.888628e-03 5.807448e-02 2.884600e-01 5.541848e-03 0 46 FALSE TRUE 60 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5881499 0.6460120 U 0.4686274 0.6162291 13773 129 182606 182607 1 -10 Convergent + - 0.000000 0 0.000000 -0.53138184 1.512006 3.262629 1.0978213 77 Prephenate dehydratase E chorismate mutase/prephenate dehydratase (P-protein) 1.400468 3.126320 1.1163000 1204 Superfamily II helicase R ATP-dependent, DNA binding helicase 2.115434e-03 11 1.244068e-02 -3.086708e-03 -1.809697e-02 -2.394262e-01 9.831872e-01 46 11 TRUE TRUE 61 FALSE 0.4469764 0.2336233 0.5480306 0.4469764 0.7764261 0.4978055 0.4539367 0.4410068 U 0.4686274 0.5361920 13773 129 182607 182608 1 34 Same - - 0.000000 0 0.000000 0.00000000 1.400468 3.126320 1.1163000 1204 Superfamily II helicase R ATP-dependent, DNA binding helicase 1.669197 3.827928 1.1692134 - - - hypothetical protein 0.000000e+00 0 7.221541e-02 -1.109170e-02 4.935327e-03 -3.948937e-01 1.864074e+00 11 0 FALSE TRUE 60 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4203740 0.4101240 U 0.4686274 0.6162291 13773 129 182608 182609 1 483 Divergent - + 0.000000 0 0.000000 0.00000000 1.669197 3.827928 1.1692134 - - - hypothetical protein 1.317147 2.896654 1.0176715 1241 Predicted ATPase involved in replication control, Cdc46/Mcm family L DNA replication licensing factor (mcm) 0.000000e+00 0 1.239392e-01 -2.923931e-02 -3.958404e-01 -8.568172e-01 3.429461e+00 0 10 FALSE TRUE 59 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3803337 0.3996808 U 0.4686274 0.6162291 13773 129 182609 182610 1 56 Same + + 0.000000 0 0.000000 0.00000000 1.317147 2.896654 1.0176715 1241 Predicted ATPase involved in replication control, Cdc46/Mcm family L DNA replication licensing factor (mcm) 1.432233 3.080251 0.9973433 - - - paREP8 0.000000e+00 0 1.324483e-02 2.572114e-03 5.976864e-03 7.827029e-02 6.655454e-01 10 0 TRUE TRUE 60 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178028 0.4693615 U 0.4686274 0.6162291 13773 129 182610 182611 1 399 Same + + 0.000000 0 0.000000 0.00000000 1.432233 3.080251 0.9973433 - - - paREP8 1.614890 3.544759 1.0553635 - - - hypothetical protein 0.000000e+00 0 3.336351e-02 -3.132558e-03 5.106307e-02 -7.707227e-02 9.514857e-01 0 0 TRUE TRUE 61 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4990412 0.4425379 U 0.4686274 0.6162291 13773 129 182611 182612 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.614890 3.544759 1.0553635 - - - hypothetical protein 1.450176 3.186206 1.0696120 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 2.713065e-02 -1.989351e-04 -4.946892e-02 7.639022e-02 6.444282e-01 0 4 TRUE TRUE 62 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178388 0.4709442 U 0.4686274 0.6162291 13773 129 182612 182613 1 -21 Same + + 2.813411 0 2.813411 2.75278609 1.450176 3.186206 1.0696120 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.405885 3.088764 1.0044692 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 6.136219e-02 3 1.961704e-03 5.537170e-05 2.664059e-02 -3.027902e-02 1.920363e-01 4 3 TRUE TRUE 63 TRUE 2.9158527 1.7134129 0.5480306 2.9317243 0.7136133 0.8901821 0.5119398 0.5824114 U 0.4686274 0.8486894 13773 129 182613 182614 1 40 Same + + 0.000000 0 0.000000 0.00000000 1.405885 3.088764 1.0044692 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.413613 2.805570 0.9759612 - - - paREP7 0.000000e+00 0 5.972353e-05 1.719277e-03 3.920539e-02 9.678474e-02 6.008332e-03 3 0 TRUE TRUE 64 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181938 0.6454790 U 0.4686274 0.6162291 13773 129 182614 182615 1 244 Convergent + - 0.000000 0 0.000000 0.00000000 1.413613 2.805570 0.9759612 - - - paREP7 1.466235 3.526198 1.0785862 - - - hypothetical protein 0.000000e+00 0 2.769037e-03 -5.607222e-04 1.111630e-02 -6.325800e-02 2.550134e-01 0 0 TRUE TRUE 65 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5030259 0.5607931 U 0.4686274 0.6162291 13773 129 182615 182616 1 86 Divergent - + 0.000000 0 0.000000 0.00000000 1.466235 3.526198 1.0785862 - - - hypothetical protein 1.401141 3.326478 1.1905569 - - - hypothetical protein 0.000000e+00 0 4.237151e-03 -7.458264e-04 1.787068e-02 -9.382681e-02 4.067366e-01 0 0 FALSE TRUE 64 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4942204 0.5111403 U 0.4686274 0.6162291 13773 129 182616 182617 1 103 Same + + 0.000000 0 0.000000 0.00000000 1.401141 3.326478 1.1905569 - - - hypothetical protein 1.736141 4.077092 1.0654721 - - - conserved within P. aerophilum 0.000000e+00 0 1.122247e-01 -1.430902e-02 5.292676e-02 -4.000150e-01 1.929605e+00 0 0 TRUE TRUE 65 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4193145 0.4092599 U 0.4686274 0.6162291 13773 129 182617 182618 1 696 Same + + 0.000000 0 0.000000 0.00000000 1.736141 4.077092 1.0654721 - - - conserved within P. aerophilum 1.432814 3.490229 1.1112725 4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase O hypothetical protein 0.000000e+00 0 9.200709e-02 -5.290252e-03 -2.461479e-01 -7.608571e-02 1.121681e+00 0 0 TRUE TRUE 66 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4992186 0.4317105 U 0.4686274 0.6162291 13773 129 182618 182619 1 16 Same + + 0.000000 0 0.000000 0.00000000 1.432814 3.490229 1.1112725 4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase O hypothetical protein 1.390180 3.166037 1.0456348 - - - hypothetical protein 0.000000e+00 0 1.817693e-03 1.137261e-03 4.267397e-02 3.884595e-02 1.794690e-01 0 0 TRUE TRUE 67 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180728 0.5852468 U 0.4686274 0.6162291 13773 129 182619 182620 1 -25 Same + + 0.000000 0 0.000000 0.00000000 1.390180 3.166037 1.0456348 - - - hypothetical protein 1.497664 3.478799 1.0788891 - - - hypothetical protein 0.000000e+00 0 1.155280e-02 -2.832383e-03 -1.645792e-02 -2.465372e-01 9.862334e-01 0 0 TRUE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4528104 0.4407019 U 0.4686274 0.6162291 13773 129 182620 182621 1 83 Same + + 0.000000 0 0.000000 0.00000000 1.497664 3.478799 1.0788891 - - - hypothetical protein 1.475008 3.347439 1.1696371 - - - hypothetical protein 0.000000e+00 0 5.132900e-04 1.092683e-03 2.949278e-02 1.555487e-01 3.088746e-02 0 0 TRUE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5326737 0.6324772 U 0.4686274 0.6162291 13773 129 182621 182622 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.475008 3.347439 1.1696371 - - - hypothetical protein 1.465331 3.277503 1.0865923 - - - P. aerophilum family 1964 protein part 1, authentic frameshift 0.000000e+00 0 9.363579e-05 3.291540e-04 2.366343e-02 7.085838e-02 8.481519e-03 0 0 TRUE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180623 0.6437931 U 0.4686274 0.6162291 13773 129 182622 182623 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.465331 3.277503 1.0865923 - - - P. aerophilum family 1964 protein part 1, authentic frameshift 1.609334 3.442157 1.0704173 - - - P. aerophilum family 1964 protein part 2, authentic frameshift 0.000000e+00 0 2.073672e-02 2.201440e-03 1.093330e-01 1.977843e-01 4.335965e-01 0 0 TRUE TRUE 71 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5494867 0.5065808 U 0.4686274 0.6162291 13773 129 182623 182624 1 -28 Convergent + - 0.000000 0 0.000000 0.00000000 1.609334 3.442157 1.0704173 - - - P. aerophilum family 1964 protein part 2, authentic frameshift 1.366715 3.056843 1.0457874 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E histidinol-phosphate aminotransferase (hisC) 0.000000e+00 0 5.886388e-02 -1.337411e-02 -1.807758e-01 -6.062225e-01 2.463189e+00 0 41 TRUE TRUE 72 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3933493 0.4037247 U 0.4686274 0.6162291 13773 129 182624 182625 1 14 Same - - 0.000000 0 0.000000 0.00000000 1.366715 3.056843 1.0457874 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E histidinol-phosphate aminotransferase (hisC) 1.349076 2.887138 0.9626965 - - - paREP15, putative coiled-coil protein 0.000000e+00 0 3.111460e-04 8.664014e-03 1.304163e-01 5.382201e-01 9.350875e-03 41 0 FALSE TRUE 71 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6908093 0.6432396 U 0.4686274 0.6162291 13773 129 182625 182626 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.349076 2.887138 0.9626965 - - - paREP15, putative coiled-coil protein 1.386220 2.979124 1.0475468 1243 Histone acetyltransferase KB conserved hypothetical protein 0.000000e+00 0 1.379745e-03 6.668256e-03 8.290554e-02 4.215557e-01 6.031303e-02 0 11 FALSE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6447252 0.6204913 U 0.4686274 0.6162291 13773 129 182626 182627 1 147 Divergent - + 0.000000 0 0.000000 0.00000000 1.386220 2.979124 1.0475468 1243 Histone acetyltransferase KB conserved hypothetical protein 1.437285 3.065015 1.0790153 - - - hypothetical protein 0.000000e+00 0 2.607541e-03 9.194683e-04 2.120744e-02 2.270868e-02 2.457968e-01 11 0 FALSE TRUE 69 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174969 0.5639198 U 0.4686274 0.6162291 13773 129 182627 182628 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.437285 3.065015 1.0790153 - - - hypothetical protein 1.528117 3.354155 1.1179660 - - - conserved hypothetical protein 0.000000e+00 0 8.250507e-03 -1.082443e-03 2.252501e-02 -2.815099e-02 5.028693e-01 0 1 TRUE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5127328 0.4922710 U 0.4686274 0.6162291 13773 129 182628 182629 1 -12 Same + + 0.000000 0 0.000000 0.00000000 1.528117 3.354155 1.1179660 - - - conserved hypothetical protein 1.585681 3.723899 1.1653564 - - - hypothetical protein 0.000000e+00 0 3.313572e-03 1.030309e-02 1.720507e-01 5.589251e-01 2.929010e-02 1 0 TRUE TRUE 71 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7027872 0.6334684 U 0.4686274 0.6162291 13773 129 182629 182630 1 -21 Same + + 0.000000 0 0.000000 0.00000000 1.585681 3.723899 1.1653564 - - - hypothetical protein 1.458876 3.133471 1.0541428 500 SAM-dependent methyltransferases QR conserved hypothetical protein 0.000000e+00 0 1.607946e-02 1.004856e-03 -1.316648e-02 1.389273e-01 4.519802e-01 0 0 TRUE TRUE 72 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5269771 0.5034307 U 0.4686274 0.6162291 13773 129 182630 182631 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.458876 3.133471 1.0541428 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.557299 3.405976 1.0778474 - - - hypothetical protein 0.000000e+00 0 9.687242e-03 7.924843e-04 5.834513e-02 1.272228e-01 3.620289e-01 0 0 TRUE TRUE 73 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5235175 0.5204865 U 0.4686274 0.6162291 13773 129 182631 182632 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.557299 3.405976 1.0778474 - - - hypothetical protein 1.491024 3.438312 1.1452904 - - - hypothetical protein 0.000000e+00 0 4.392412e-03 4.197225e-03 4.531780e-02 3.427947e-01 1.029115e-01 0 0 FALSE TRUE 72 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6098326 0.6052131 U 0.4686274 0.6162291 13773 129 182632 182633 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.491024 3.438312 1.1452904 - - - hypothetical protein 1.506545 3.433118 1.1483105 - - - hypothetical protein 0.000000e+00 0 2.408961e-04 2.185757e-03 5.003009e-02 2.440699e-01 9.954005e-03 0 0 FALSE TRUE 71 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5674389 0.6428219 U 0.4686274 0.6162291 13773 129 182633 182634 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.506545 3.433118 1.1483105 - - - hypothetical protein 1.513387 3.615644 1.1669097 - - - hypothetical protein 0.000000e+00 0 4.680888e-05 3.419099e-03 6.275012e-02 3.187167e-01 1.357043e-03 0 0 FALSE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5989764 0.6512883 U 0.4686274 0.6162291 13773 129 182634 182635 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.513387 3.615644 1.1669097 - - - hypothetical protein 1.486326 3.294613 1.1368289 - - - hypothetical protein 0.000000e+00 0 7.323021e-04 2.165621e-03 3.939776e-02 2.439615e-01 2.722627e-02 0 0 FALSE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5672352 0.6344003 U 0.4686274 0.6162291 13773 129 182635 182636 1 109 Divergent - + 0.000000 0 0.000000 0.00000000 1.486326 3.294613 1.1368289 - - - hypothetical protein 1.453178 3.209656 1.0907752 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O conserved hypothetical protein 0.000000e+00 0 1.098772e-03 6.235783e-05 1.837592e-02 4.879230e-02 9.096960e-02 0 4 FALSE TRUE 68 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187680 0.6104368 U 0.4686274 0.6162291 13773 129 182636 182637 1 -3 Convergent + - 0.000000 0 0.000000 -0.24987868 1.453178 3.209656 1.0907752 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O conserved hypothetical protein 1.365079 2.973028 1.0308492 1571 Predicted DNA-binding protein containing a Zn-ribbon domain R conserved hypothetical protein 6.304986e-02 4 7.761460e-03 -1.540774e-04 3.784773e-02 -8.111160e-02 6.592991e-01 4 9 TRUE TRUE 69 FALSE 0.4469764 0.2646721 0.5480306 0.4469764 0.7323301 0.8982713 0.4976757 0.4697032 U 0.4686274 0.5460148 13773 129 182637 182638 1 -3 Same - - 0.000000 0 0.000000 -0.27068181 1.365079 2.973028 1.0308492 1571 Predicted DNA-binding protein containing a Zn-ribbon domain R conserved hypothetical protein 1.425728 3.134281 1.0920087 614 ABC-type Fe3+-hydroxamate transport system, periplasmic component P conserved hypothetical protein 6.304986e-02 4 3.678275e-03 2.215276e-03 2.939246e-02 1.152638e-01 2.804202e-01 9 4 FALSE TRUE 68 TRUE 0.4469764 0.2582304 0.5480306 0.4469764 0.7323301 0.8982713 0.5211902 0.5510159 U 0.4686274 0.5439795 13773 129 182638 182639 1 315 Same - - 0.000000 0 0.000000 0.00000000 1.425728 3.134281 1.0920087 614 ABC-type Fe3+-hydroxamate transport system, periplasmic component P conserved hypothetical protein 1.357147 3.327950 1.0897331 - - - conserved hypothetical protein 0.000000e+00 0 4.703279e-03 2.418844e-03 6.990328e-02 1.222611e-01 3.269066e-01 4 0 FALSE TRUE 67 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5224983 0.5320384 U 0.4686274 0.6162291 13773 129 182639 182640 1 268 Divergent - + 0.000000 0 0.000000 0.00000000 1.357147 3.327950 1.0897331 - - - conserved hypothetical protein 1.464238 3.241085 1.0725587 - - - hypothetical protein 0.000000e+00 0 1.146849e-02 -1.210614e-03 -1.555471e-02 -1.573546e-01 9.041777e-01 0 0 FALSE TRUE 66 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4751134 0.4460064 U 0.4686274 0.6162291 13773 129 182640 182641 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.464238 3.241085 1.0725587 - - - hypothetical protein 1.461349 3.153058 1.0630435 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 0.000000e+00 0 8.349897e-06 1.278836e-04 2.206562e-02 4.077137e-02 4.953443e-04 0 0 TRUE TRUE 67 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182668 0.6533218 U 0.4686274 0.6162291 13773 129 182641 182642 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.461349 3.153058 1.0630435 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 1.435906 3.088495 1.0889707 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 0.000000e+00 0 6.473150e-04 -1.541807e-04 1.929233e-02 -1.026617e-02 5.993666e-02 C 0 0 FALSE TRUE 66 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185396 0.6206752 Y 1.4497162 0.7118045 13773 129 182642 182643 1 114 Same - - 0.000000 0 0.000000 0.00000000 1.435906 3.088495 1.0889707 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 1.562464 3.520473 1.0390130 - - - hypothetical protein 0.000000e+00 0 1.601700e-02 -1.720133e-03 3.134600e-02 -4.213666e-02 7.023546e-01 0 0 FALSE TRUE 65 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5084870 0.4645365 U 0.4686274 0.6162291 13773 129 182643 182644 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.562464 3.520473 1.0390130 - - - hypothetical protein 1.459442 3.702968 1.1911268 2095 Multiple antibiotic transporter U conserved hypothetical protein part 2, authentic frameshift 0.000000e+00 0 1.061355e-02 8.940692e-04 2.628400e-05 1.396529e-01 3.675914e-01 0 0 FALSE TRUE 64 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5273697 0.5196393 U 0.4686274 0.6162291 13773 129 182644 182645 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.459442 3.702968 1.1911268 2095 Multiple antibiotic transporter U conserved hypothetical protein part 2, authentic frameshift 1.608405 3.878638 1.1177668 2095 Multiple antibiotic transporter U conserved hypothetical protein part 1, authentic frameshift 0.000000e+00 0 2.218994e-02 1.263869e-03 9.795687e-02 1.567338e-01 4.931208e-01 U 0 0 FALSE TRUE 63 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5329434 0.4934901 Y 1.4497162 0.7118045 13773 129 182645 182646 1 235 Same - - 0.000000 0 0.000000 0.00000000 1.608405 3.878638 1.1177668 2095 Multiple antibiotic transporter U conserved hypothetical protein part 1, authentic frameshift 1.339448 2.794488 1.0130874 1980 Archaeal fructose 1,6-bisphosphatase G conserved hypothetical protein 0.000000e+00 0 7.233788e-02 -1.757670e-02 -2.155561e-01 -7.350273e-01 2.942160e+00 0 0 13 FALSE TRUE 62 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3853423 0.4011162 N 0.5492530 0.6245624 13773 129 182646 182647 1 7 Divergent - + 0.000000 0 0.000000 0.00000000 1.339448 2.794488 1.0130874 1980 Archaeal fructose 1,6-bisphosphatase G conserved hypothetical protein 1.506580 3.217210 1.0081269 454 Histone acetyltransferase HPA2 and related acetyltransferases KR conserved hypothetical protein 0.000000e+00 0 2.793309e-02 -6.177924e-03 -7.558603e-02 -4.569089e-01 1.910463e+00 13 0 FALSE TRUE 61 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4110840 0.4096714 U 0.4686274 0.6162291 13773 129 182647 182648 1 66 Same + + 0.000000 0 0.000000 0.00000000 1.506580 3.217210 1.0081269 454 Histone acetyltransferase HPA2 and related acetyltransferases KR conserved hypothetical protein 1.416679 3.087727 1.0477793 505 Carbamoylphosphate synthase small subunit EF carbamoyl-phosphate synthase small subunit 0.000000e+00 0 8.082281e-03 -1.915783e-03 -6.336311e-03 -1.356448e-01 6.321653e-01 0 62 TRUE TRUE 62 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4805186 0.4727649 U 0.4686274 0.6162291 13773 129 182648 182649 1 -10 Same + + 67.140257 0 171.302008 169.13232703 1.416679 3.087727 1.0477793 505 Carbamoylphosphate synthase small subunit EF carbamoyl-phosphate synthase small subunit 1.375613 2.993771 1.0833492 458 Carbamoylphosphate synthase large subunit (split gene in MJ) EF carbamoyl-phosphate synthase large subunit 2.613429e-01 54 1.686368e-03 2.630629e-03 6.301869e-02 1.548596e-01 1.419954e-01 62 54 TRUE TRUE 63 TRUE 2.0240781 2.0809063 0.5480306 2.0271885 0.7712119 1.1980473 0.5321358 0.5953411 U 0.4686274 0.9091377 13773 129 182649 182650 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.375613 2.993771 1.0833492 458 Carbamoylphosphate synthase large subunit (split gene in MJ) EF carbamoyl-phosphate synthase large subunit 1.386683 3.038612 1.0565477 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 0.000000e+00 0 1.225476e-04 4.903660e-03 7.412313e-02 3.332118e-01 8.340750e-03 54 0 TRUE TRUE 64 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6052650 0.6438916 U 0.4686274 0.6162291 13773 129 182650 182651 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.386683 3.038612 1.0565477 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 1.468860 3.304613 1.1208190 309 Hydrogenase maturation factor O hydrogenase expression/formation protein HypE 0.000000e+00 0 6.752968e-03 -1.130278e-03 -2.336776e-03 -1.371326e-01 6.248642e-01 0 18 TRUE TRUE 65 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4801497 0.4739005 U 0.4686274 0.6162291 13773 129 182651 182652 1 27 Divergent - + 0.000000 0 0.000000 0.00000000 1.468860 3.304613 1.1208190 309 Hydrogenase maturation factor O hydrogenase expression/formation protein HypE 1.390032 3.050840 1.0617509 1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR KE aminotransferase, conjectural 0.000000e+00 0 6.213868e-03 -1.071792e-03 1.699294e-02 -1.294374e-01 5.784402e-01 18 0 FALSE TRUE 64 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4817403 0.4799478 U 0.4686274 0.6162291 13773 129 182652 182653 1 14 Same + + 0.000000 0 0.000000 0.00000000 1.390032 3.050840 1.0617509 1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR KE aminotransferase, conjectural 1.514504 3.254372 1.0717942 1628 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.549345e-02 -3.872596e-03 -2.398849e-02 -2.967401e-01 1.194349e+00 0 2 TRUE TRUE 65 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4411298 0.4283385 U 0.4686274 0.6162291 13773 129 182653 182654 1 -6 Same + + 0.000000 0 0.000000 0.00000000 1.514504 3.254372 1.0717942 1628 Uncharacterized conserved protein S conserved hypothetical protein 1.366875 2.909193 1.0267602 687 Spermidine/putrescine-binding periplasmic protein E putrescine/spermidine binding protein, conjectural 1.430590e-02 2 2.179448e-02 -5.334061e-03 -3.360423e-02 -4.039465e-01 1.624989e+00 2 30 TRUE TRUE 66 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.6337586 0.4188892 0.4139867 U 0.4686274 0.6162291 13773 129 182654 182655 1 173 Convergent + - 0.000000 0 0.000000 0.00000000 1.366875 2.909193 1.0267602 687 Spermidine/putrescine-binding periplasmic protein E putrescine/spermidine binding protein, conjectural 1.466248 3.059054 1.0496699 - - - paREP2b 0.000000e+00 0 9.875050e-03 -1.255540e-03 -1.152246e-02 -1.583176e-01 8.396916e-01 30 0 TRUE TRUE 67 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4745968 0.4516044 U 0.4686274 0.6162291 13773 129 182655 182656 1 3 Divergent - + 0.000000 0 0.000000 0.00000000 1.466248 3.059054 1.0496699 - - - paREP2b 1.644157 3.489375 1.1271705 - - - paREP2a 0.000000e+00 0 3.165170e-02 2.863574e-03 1.480225e-01 2.143404e-01 4.856047e-01 0 0 FALSE TRUE 66 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5550161 0.4950121 U 0.4686274 0.6162291 13773 129 182656 182657 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.644157 3.489375 1.1271705 - - - paREP2a 1.454602 3.067897 1.0447487 118 Glutamine amidotransferase E amidotransferase (hisH) 0.000000e+00 0 3.593134e-02 6.185602e-04 -6.636728e-02 1.174955e-01 6.419662e-01 0 52 TRUE TRUE 67 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5216828 0.4710831 U 0.4686274 0.6162291 13773 129 182657 182658 1 -20 Convergent + - 6.112575 0 9.082990 8.86124587 1.454602 3.067897 1.0447487 118 Glutamine amidotransferase E amidotransferase (hisH) 1.296632 2.881735 0.9748761 139 Phosphoribosyl-AMP cyclohydrolase E phosphoribosyl-AMP cyclohydrolase 4.085506e-02 8 2.495434e-02 -4.966095e-04 7.572838e-02 -1.204111e-01 1.161035e+00 E 52 8 TRUE TRUE 68 FALSE 2.7711050 1.8252021 0.5480306 2.7823725 0.7652913 0.8065087 0.4851003 0.4302352 Y 1.4497162 0.9101386 13773 129 182658 182659 1 101 Divergent - + 0.000000 0 0.000000 -0.01801851 1.296632 2.881735 0.9748761 139 Phosphoribosyl-AMP cyclohydrolase E phosphoribosyl-AMP cyclohydrolase 1.420531 3.108098 1.0825802 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E histidinol-phosphate aminotransferase (hisC) 1.780802e-03 8 1.535084e-02 4.776226e-03 1.817812e-02 2.036042e-01 5.428172e-01 E 8 14 FALSE TRUE 67 FALSE 0.4469764 0.3087842 0.5480306 0.4469764 0.7652913 0.4905695 0.5507909 0.4845925 Y 1.4497162 0.6618114 13773 129 182659 182660 1 42 Same + + 0.000000 0 0.000000 0.00000000 1.420531 3.108098 1.0825802 79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase E histidinol-phosphate aminotransferase (hisC) 1.466604 3.447424 1.1544730 - - - paREP1, degenerate 0.000000e+00 0 2.122722e-03 -4.694415e-04 1.341763e-02 -5.044914e-02 2.022583e-01 14 0 TRUE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5067014 0.5792906 U 0.4686274 0.6162291 13773 129 182660 182661 1 359 Same + + 0.000000 0 0.000000 0.00000000 1.466604 3.447424 1.1544730 - - - paREP1, degenerate 1.390198 3.180899 1.1232359 40 ATP phosphoribosyltransferase E ATP phosphoribosyltransferase (hisG) 0.000000e+00 0 5.837921e-03 -9.308400e-04 1.877660e-02 -1.178955e-01 5.416870e-01 0 21 TRUE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4856918 0.4848191 U 0.4686274 0.6162291 13773 129 182661 182662 1 503 Same + + 0.000000 0 0.000000 -5.24074230 1.390198 3.180899 1.1232359 40 ATP phosphoribosyltransferase E ATP phosphoribosyltransferase (hisG) 1.387480 2.980088 1.0448866 125 Thymidylate kinase F thymidylate kinase (tmk) 2.897276e-03 21 7.387617e-06 3.911197e-03 6.733206e-02 2.619046e-01 5.300950e-04 0 21 60 TRUE TRUE 70 TRUE 0.4469764 0.1824277 0.5480306 0.4469764 0.7775415 0.5125675 0.5749072 0.6531640 N 0.5492530 0.5287628 13773 129 182662 182663 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.387480 2.980088 1.0448866 125 Thymidylate kinase F thymidylate kinase (tmk) 1.420478 3.229922 1.0867249 - - - hypothetical protein 0.000000e+00 0 1.088876e-03 1.975895e-03 3.589386e-02 1.124744e-01 9.518385e-02 60 0 TRUE TRUE 71 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5201912 0.6086719 U 0.4686274 0.6162291 13773 129 182663 182664 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.420478 3.229922 1.0867249 - - - hypothetical protein 1.447961 3.442078 1.1399522 1266 Predicted metal-dependent membrane protease R conserved hypothetical protein 0.000000e+00 0 7.553258e-04 1.061017e-04 1.958104e-02 -1.335839e-02 7.675834e-02 0 0 FALSE TRUE 70 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173066 0.6159494 U 0.4686274 0.6162291 13773 129 182664 182665 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.447961 3.442078 1.1399522 1266 Predicted metal-dependent membrane protease R conserved hypothetical protein 1.663790 3.501288 1.0719524 1611 Predicted Rossmann fold nucleotide-binding protein R conserved hypothetical protein 0.000000e+00 0 4.658244e-02 -7.289534e-04 1.267489e-01 5.863380e-02 7.762381e-01 0 3 TRUE TRUE 71 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186320 0.4577766 U 0.4686274 0.6162291 13773 129 182665 182666 1 -3 Same - - 0.000000 0 0.000000 -0.31372225 1.663790 3.501288 1.0719524 1611 Predicted Rossmann fold nucleotide-binding protein R conserved hypothetical protein 1.386358 3.029650 1.0020071 521 Molybdopterin biosynthesis enzymes H molybdenum cofactor biosynthesis protein (moaB) 3.253907e-02 3 7.696879e-02 -1.381325e-02 -2.445940e-01 -5.059880e-01 2.189401e+00 3 34 FALSE TRUE 70 TRUE 0.4469764 0.2527773 0.5480306 0.4469764 0.7136133 0.7528976 0.4050609 0.4058902 U 0.4686274 0.5422555 13773 129 182666 182667 1 17 Same - - 0.000000 0 0.000000 0.00000000 1.386358 3.029650 1.0020071 521 Molybdopterin biosynthesis enzymes H molybdenum cofactor biosynthesis protein (moaB) 1.494421 3.339597 1.0525629 3255 Putative sterol carrier protein I conserved hypothetical protein 0.000000e+00 0 1.167753e-02 -2.798304e-03 -1.802019e-02 -2.511413e-01 1.009231e+00 0 34 0 FALSE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4518346 0.4388235 N 0.5492530 0.6245624 13773 129 182667 182668 1 31 Divergent - + 0.000000 0 0.000000 0.00000000 1.494421 3.339597 1.0525629 3255 Putative sterol carrier protein I conserved hypothetical protein 1.431435 3.023164 1.0401514 4996 Predicted phosphatase R conserved hypothetical protein 0.000000e+00 0 3.967138e-03 -8.587249e-04 7.007110e-03 -4.598868e-02 3.207923e-01 0 3 FALSE TRUE 68 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5075334 0.5347337 U 0.4686274 0.6162291 13773 129 182668 182669 1 -8 Convergent + - 0.000000 0 0.000000 -0.13150953 1.431435 3.023164 1.0401514 4996 Predicted phosphatase R conserved hypothetical protein 1.376480 3.024022 1.0766245 15 Adenylosuccinate lyase F adenylosuccinate lyase (purB) 1.178361e-03 3 3.020112e-03 1.495074e-03 5.145865e-02 6.061459e-02 2.691563e-01 3 57 TRUE TRUE 69 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7136133 0.4775709 0.5185170 0.5538632 U 0.4686274 0.5537552 13773 129 182669 182670 1 6 Same - - 0.000000 0 0.000000 -0.07232066 1.376480 3.024022 1.0766245 15 Adenylosuccinate lyase F adenylosuccinate lyase (purB) 1.493159 3.251390 1.0517638 - - - paREP1 3.554731e-03 1 1.361393e-02 -3.128796e-03 -2.566683e-02 -2.827102e-01 1.156079e+00 57 1 FALSE TRUE 68 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.5281729 0.4447161 0.4303479 U 0.4686274 0.5573725 13773 129 182670 182671 1 21 Same - - 0.000000 0 0.000000 -0.07232066 1.493159 3.251390 1.0517638 - - - paREP1 1.404958 3.043681 1.0660468 104 Adenylosuccinate synthase F adenylosuccinate synthetase (purA) 3.317640e-03 1 7.779405e-03 -1.939400e-03 -8.924127e-04 -1.666725e-01 6.756007e-01 1 58 FALSE TRUE 67 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.5238969 0.4728998 0.4673400 U 0.4686274 0.5573725 13773 129 182671 182672 1 331 Divergent - + 0.000000 0 0.000000 0.00000000 1.404958 3.043681 1.0660468 104 Adenylosuccinate synthase F adenylosuccinate synthetase (purA) 1.390835 3.141533 1.0753401 2886 Uncharacterized small protein S hypothetical protein 0.000000e+00 0 1.994503e-04 2.812020e-03 5.745389e-02 1.809108e-01 1.783239e-02 58 0 FALSE TRUE 66 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5423788 0.6388731 U 0.4686274 0.6162291 13773 129 182672 182673 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.390835 3.141533 1.0753401 2886 Uncharacterized small protein S hypothetical protein 1.567405 3.727032 1.1397007 - - - hypothetical protein 0.000000e+00 0 3.117687e-02 -7.025433e-03 -3.654009e-02 -3.965534e-01 1.676260e+00 0 0 TRUE TRUE 67 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4199509 0.4127699 U 0.4686274 0.6162291 13773 129 182673 182674 1 83 Same + + 0.000000 0 0.000000 0.00000000 1.567405 3.727032 1.1397007 - - - hypothetical protein 1.560821 3.559673 1.1465521 - - - hypothetical protein 0.000000e+00 0 4.334797e-05 1.269493e-02 1.654011e-01 6.229806e-01 2.597465e-04 0 0 TRUE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7276519 0.6541658 U 0.4686274 0.6162291 13773 129 182674 182675 1 75 Same + + 0.000000 0 0.000000 0.00000000 1.560821 3.559673 1.1465521 - - - hypothetical protein 1.422157 3.082070 1.0080655 - - - paREP1 0.000000e+00 0 1.922765e-02 -3.199221e-03 -4.490716e-02 -1.576938e-01 9.665168e-01 0 1 TRUE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4749845 0.4418015 U 0.4686274 0.6162291 13773 129 182675 182676 1 256 Same + + 0.000000 0 0.000000 -0.07232066 1.422157 3.082070 1.0080655 - - - paREP1 1.325053 2.947385 1.0237643 2509 Uncharacterized FAD-dependent dehydrogenases R conserved hypothetical protein 1.599790e-02 1 9.429170e-03 3.693655e-03 1.022893e-01 1.781414e-01 4.634025e-01 1 23 TRUE TRUE 70 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.6457313 0.5416419 0.5009016 U 0.4686274 0.5573725 13773 129 182676 182677 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.325053 2.947385 1.0237643 2509 Uncharacterized FAD-dependent dehydrogenases R conserved hypothetical protein 1.593140 3.670237 1.1353504 - - - P. aerophilum family 70 protein 0.000000e+00 0 7.187037e-02 -1.790825e-02 -1.781614e-01 -7.545607e-01 3.019006e+00 23 0 TRUE TRUE 71 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3846295 0.4010478 U 0.4686274 0.6162291 13773 129 182677 182678 1 -30 Same - - 0.000000 0 0.000000 0.00000000 1.593140 3.670237 1.1353504 - - - P. aerophilum family 70 protein 1.530368 3.332320 1.1476396 - - - P. aerophilum family 68 protein 0.000000e+00 0 3.940298e-03 1.119443e-02 1.164410e-01 5.819960e-01 3.035029e-02 0 0 FALSE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7139944 0.6329638 U 0.4686274 0.6162291 13773 129 182678 182679 1 71 Same - - 0.000000 0 0.000000 0.00000000 1.530368 3.332320 1.1476396 - - - P. aerophilum family 68 protein 1.444005 3.275801 1.1260071 140 Phosphoribosyl-ATP pyrophosphohydrolase E phosphoribosyl-ATP pyrophosphohydrolase 0.000000e+00 0 7.458501e-03 -5.834435e-04 -1.784500e-03 1.724046e-02 4.295630e-01 0 0 FALSE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178886 0.5075206 U 0.4686274 0.6162291 13773 129 182679 182680 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.444005 3.275801 1.1260071 140 Phosphoribosyl-ATP pyrophosphohydrolase E phosphoribosyl-ATP pyrophosphohydrolase 1.410435 3.134864 1.0727137 141 Histidinol dehydrogenase E histidinol dehydrogenase (hisD) 0.000000e+00 0 1.126987e-03 3.025882e-04 2.839728e-02 -7.852473e-03 1.124797e-01 E 0 39 FALSE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192694 0.6023797 Y 1.4497162 0.7118045 13773 129 182680 182681 1 -3 Same - - 27.665484 0 74.495563 72.15469778 1.410435 3.134864 1.0727137 141 Histidinol dehydrogenase E histidinol dehydrogenase (hisD) 1.446348 3.093873 1.0354113 107 Imidazoleglycerol-phosphate synthase E histidine biosynthesis protein (hisF,cyclase) 2.781752e-01 39 1.289786e-03 2.066243e-04 1.895798e-02 -1.403927e-02 1.262621e-01 E 39 53 FALSE TRUE 67 TRUE 2.2022561 2.0566053 0.5480306 2.1155991 0.7736367 1.2068002 0.5171033 0.5992342 Y 1.4497162 0.9358775 13773 129 182681 182682 1 58 Divergent - + 37.020747 0 82.487098 81.30900550 1.446348 3.093873 1.0354113 107 Imidazoleglycerol-phosphate synthase E histidine biosynthesis protein (hisF,cyclase) 1.340967 2.960476 1.0360942 131 Imidazoleglycerol-phosphate dehydratase E imidazoleglycerol-phosphate dehydratase 4.479544e-01 49 1.110514e-02 5.570690e-04 5.815279e-02 -3.746122e-02 7.614337e-01 E 53 49 FALSE TRUE 66 FALSE 2.1285374 2.0654173 0.5480306 2.0895980 0.7715903 1.2560189 0.5096928 0.4584148 Y 1.4497162 0.9370890 13773 129 182682 182683 1 -3 Same + + 35.357409 0 57.105356 56.92724193 1.340967 2.960476 1.0360942 131 Imidazoleglycerol-phosphate dehydratase E imidazoleglycerol-phosphate dehydratase 1.416831 3.047639 1.0442810 106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase E phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA) 2.329949e-01 30 5.755339e-03 3.816498e-03 3.742840e-02 2.044494e-01 3.366315e-01 E 49 30 TRUE TRUE 67 TRUE 2.1369229 2.0456300 0.5480306 2.1745431 0.7754515 1.1678826 0.5511204 0.5289643 Y 1.4497162 0.9355235 13773 129 182683 182684 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.416831 3.047639 1.0442810 106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase E phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (hisA) 1.642053 3.602602 1.1115853 - - - hypothetical protein 0.000000e+00 0 5.072494e-02 -6.589543e-03 3.297198e-02 -2.281564e-01 1.369780e+00 30 0 TRUE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4575477 0.4210285 U 0.4686274 0.6162291 13773 129 182684 182685 1 291 Same + + 0.000000 0 0.000000 0.00000000 1.642053 3.602602 1.1115853 - - - hypothetical protein 1.513423 3.425232 1.1098669 5550 Predicted aspartyl protease O conserved within P. aerophilum 0.000000e+00 0 1.654560e-02 1.182677e-02 7.647654e-02 5.392144e-01 1.150683e-01 0 0 TRUE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6923287 0.6018877 U 0.4686274 0.6162291 13773 129 182685 182686 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.513423 3.425232 1.1098669 5550 Predicted aspartyl protease O conserved within P. aerophilum 1.622375 3.415117 1.0672559 - - - hypothetical protein 0.000000e+00 0 1.187039e-02 1.060611e-02 2.092179e-01 5.253194e-01 9.949352e-02 0 0 TRUE TRUE 70 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6866719 0.6070283 U 0.4686274 0.6162291 13773 129 182686 182687 1 22 Same - - 0.000000 0 0.000000 0.00000000 1.622375 3.415117 1.0672559 - - - hypothetical protein 1.512460 3.214004 1.0064744 - - - hypothetical protein 0.000000e+00 0 1.208118e-02 1.044144e-02 7.805032e-02 5.211776e-01 1.024196e-01 0 0 FALSE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6848113 0.6055846 U 0.4686274 0.6162291 13773 129 182687 182688 1 172 Same - - 0.000000 0 0.000000 0.00000000 1.512460 3.214004 1.0064744 - - - hypothetical protein 1.315458 2.745554 0.9626081 1690 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.881001e-02 -8.301216e-03 -3.886700e-02 -5.251798e-01 2.207608e+00 0 30 FALSE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4014305 0.4056432 U 0.4686274 0.6162291 13773 129 182688 182689 1 242 Divergent - + 0.000000 0 0.000000 0.00000000 1.315458 2.745554 0.9626081 1690 Uncharacterized conserved protein S conserved hypothetical protein 1.463640 3.280045 1.1364583 - - - P. aerophilum family 59 protein 0.000000e+00 0 2.195792e-02 -1.664796e-03 -4.527258e-02 -1.912907e-01 1.248630e+00 30 0 FALSE TRUE 67 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4669349 0.4260499 U 0.4686274 0.6162291 13773 129 182689 182690 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.463640 3.280045 1.1364583 - - - P. aerophilum family 59 protein 1.421901 3.382272 1.1026995 - - - P. aerophilum family 3 protein 0.000000e+00 0 1.742158e-03 -3.611905e-04 1.834249e-02 -4.373283e-02 1.749461e-01 0 0 TRUE TRUE 68 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5079782 0.5862680 U 0.4686274 0.6162291 13773 129 182690 182691 1 141 Same + + 0.000000 0 0.000000 0.00000000 1.421901 3.382272 1.1026995 - - - P. aerophilum family 3 protein 1.454681 3.286754 1.0352762 - - - conserved within P. aerophilum 0.000000e+00 0 1.074530e-03 -9.696579e-05 1.742256e-02 -2.639873e-02 1.119655e-01 0 0 TRUE TRUE 69 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5131973 0.6025456 U 0.4686274 0.6162291 13773 129 182691 182692 1 27 Same + + 0.000000 0 0.000000 0.00000000 1.454681 3.286754 1.0352762 - - - conserved within P. aerophilum 1.420623 3.102787 1.0536346 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E acylamino-acid-releasing enzyme, conjectural 0.000000e+00 0 1.159956e-03 -1.011680e-04 2.193179e-02 -2.708314e-02 1.155896e-01 0 15 TRUE TRUE 70 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5129980 0.6017256 U 0.4686274 0.6162291 13773 129 182692 182693 1 -7 Same + + 0.000000 0 0.000000 -1.73042047 1.420623 3.102787 1.0536346 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E acylamino-acid-releasing enzyme, conjectural 1.312403 2.917719 1.0312545 252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D EJ asparaginase (asnA) 6.227658e-02 15 1.171144e-02 4.276752e-03 1.173968e-01 1.948028e-01 4.952789e-01 15 31 TRUE TRUE 71 TRUE 0.4469764 0.1996263 0.5480306 0.4469764 0.7783720 0.8934079 0.5478867 0.4929568 U 0.4686274 0.5254044 13773 129 182693 182694 1 -3 Same + + 0.000000 0 0.000000 -0.31372225 1.312403 2.917719 1.0312545 252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D EJ asparaginase (asnA) 1.382970 2.975164 0.9960716 1896 Predicted hydrolases of HD superfamily R conserved hypothetical protein 3.646849e-02 3 4.979749e-03 9.510002e-03 9.476174e-02 5.140826e-01 1.262621e-01 31 3 TRUE TRUE 72 TRUE 0.4469764 0.2527773 0.5480306 0.4469764 0.7136133 0.7811886 0.6793058 0.5992342 U 0.4686274 0.5422555 13773 129 182694 182695 1 1576 Convergent + - 0.000000 0 0.000000 -0.31372225 1.382970 2.975164 0.9960716 1896 Predicted hydrolases of HD superfamily R conserved hypothetical protein 1.359250 2.988814 1.0025213 1779 C4-type Zn-finger protein R conserved hypothetical protein 8.710900e-02 3 5.626774e-04 6.304654e-03 1.041258e-01 4.077355e-01 2.748012e-02 3 10 TRUE TRUE 73 FALSE 0.4469764 0.2527773 0.5480306 0.4469764 0.7136133 0.9694943 0.6375549 0.6342472 U 0.4686274 0.5422555 13773 129 182695 182696 1 17 Divergent - + 0.000000 0 0.000000 0.00000000 1.359250 2.988814 1.0025213 1779 C4-type Zn-finger protein R conserved hypothetical protein 1.290763 3.298811 1.1691488 - - - hypothetical protein 0.000000e+00 0 4.690379e-03 1.480091e-02 2.377568e-01 6.994532e-01 5.551213e-02 10 0 FALSE TRUE 72 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7514208 0.6218902 U 0.4686274 0.6162291 13773 129 182696 182697 1 39 Same + + 0.000000 0 0.000000 0.00000000 1.290763 3.298811 1.1691488 - - - hypothetical protein 1.372265 3.123377 1.0681178 - - - hypothetical protein 0.000000e+00 0 6.642500e-03 1.271029e-02 1.197264e-01 6.189459e-01 1.019290e-01 0 0 TRUE TRUE 73 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7259714 0.6058668 U 0.4686274 0.6162291 13773 129 182697 182698 1 -38 Convergent + - 0.000000 0 0.000000 0.00000000 1.372265 3.123377 1.0681178 - - - hypothetical protein 1.400388 3.093652 1.0581459 1608 Predicted archaeal kinase R conserved hypothetical protein 0.000000e+00 0 7.909327e-04 4.035880e-03 5.863228e-02 2.680125e-01 5.125724e-02 0 11 TRUE TRUE 74 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5773974 0.6234508 U 0.4686274 0.6162291 13773 129 182698 182699 1 0 Same - - 18.262480 0 18.262480 17.91017974 1.400388 3.093652 1.0581459 1608 Predicted archaeal kinase R conserved hypothetical protein 1.340160 2.875683 1.0205043 142 Geranylgeranyl pyrophosphate synthase H polyprenyl synthetase 2.367901e-02 11 3.627497e-03 5.673388e-03 1.118870e-01 3.466892e-01 1.723875e-01 11 51 FALSE TRUE 73 TRUE 2.4772945 1.8965654 0.5480306 2.6365810 0.7764261 0.6990558 0.6114678 0.5871112 U 0.4686274 0.8820605 13773 129 182699 182700 1 295 Divergent - + 0.000000 0 0.000000 0.00000000 1.340160 2.875683 1.0205043 142 Geranylgeranyl pyrophosphate synthase H polyprenyl synthetase 1.631280 3.540304 1.1284556 - - - conserved within P. aerophilum 0.000000e+00 0 8.475087e-02 -2.000939e-02 -1.624618e-01 -7.610562e-01 3.051095e+00 51 0 FALSE TRUE 72 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3843917 0.4008428 U 0.4686274 0.6162291 13773 129 182700 182701 1 71 Same + + 0.000000 0 0.000000 0.00000000 1.631280 3.540304 1.1284556 - - - conserved within P. aerophilum 1.446830 3.429444 1.1177457 1836 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 3.402159e-02 -8.207481e-04 -7.098255e-02 4.914569e-02 7.414756e-01 0 0 TRUE TRUE 73 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187718 0.4605849 U 0.4686274 0.6162291 13773 129 182701 182702 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.446830 3.429444 1.1177457 1836 Predicted membrane protein S conserved hypothetical protein 1.562573 3.282928 1.0658807 432 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.339630e-02 -5.072668e-04 4.614447e-02 4.217789e-02 5.349300e-01 0 27 TRUE TRUE 74 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184055 0.4860301 U 0.4686274 0.6162291 13773 129 182702 182703 1 98 Same + + 0.000000 0 0.000000 0.00000000 1.562573 3.282928 1.0658807 432 Uncharacterized conserved protein S conserved hypothetical protein 1.394990 3.216163 1.0786175 - - - hypothetical protein 0.000000e+00 0 2.808397e-02 -6.270866e-03 -7.589487e-02 -3.645375e-01 1.561061e+00 27 0 TRUE TRUE 75 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4251715 0.4153650 U 0.4686274 0.6162291 13773 129 182703 182704 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.394990 3.216163 1.0786175 - - - hypothetical protein 1.562783 3.386144 1.0898658 - - - hypothetical protein 0.000000e+00 0 2.815445e-02 -6.282718e-03 -2.929100e-02 -3.648938e-01 1.562980e+00 0 0 TRUE TRUE 76 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4249656 0.4152379 U 0.4686274 0.6162291 13773 129 182704 182705 1 14 Divergent - + 0.000000 0 0.000000 0.00000000 1.562783 3.386144 1.0898658 - - - hypothetical protein 1.704333 3.833656 1.1369093 - - - hypothetical protein 0.000000e+00 0 2.003646e-02 2.817499e-02 4.811326e-01 7.611504e-01 3.336300e-02 0 0 FALSE TRUE 75 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7717256 0.6308211 U 0.4686274 0.6162291 13773 129 182705 182706 1 180 Same + + 0.000000 0 0.000000 0.00000000 1.704333 3.833656 1.1369093 - - - hypothetical protein 1.502367 3.411414 1.1061128 611 Thiamine monophosphate kinase H thiamine-monophosphate kinase part 2, authentic frameshift 0.000000e+00 0 4.079036e-02 1.289335e-02 1.561435e-02 5.039648e-01 2.008801e-01 0 0 TRUE TRUE 76 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6739167 0.5797853 U 0.4686274 0.6162291 13773 129 182706 182707 1 -21 Same + + 0.000000 0 0.000000 0.00000000 1.502367 3.411414 1.1061128 611 Thiamine monophosphate kinase H thiamine-monophosphate kinase part 2, authentic frameshift 1.381357 2.894604 1.0187750 - - - thiamine-monophosphate kinase part 1, authentic frameshift 0.000000e+00 0 1.464340e-02 -3.570010e-03 -1.514598e-02 -2.983056e-01 1.196027e+00 0 0 TRUE TRUE 77 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4407641 0.4281178 U 0.4686274 0.6162291 13773 129 182707 182708 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.381357 2.894604 1.0187750 - - - thiamine-monophosphate kinase part 1, authentic frameshift 1.405412 3.259606 1.1195855 - - - hypothetical protein 0.000000e+00 0 5.786685e-04 3.220288e-03 5.130284e-02 2.059101e-01 4.584791e-02 0 0 TRUE TRUE 78 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5517838 0.6256408 U 0.4686274 0.6162291 13773 129 182708 182709 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.405412 3.259606 1.1195855 - - - hypothetical protein 1.454341 3.190910 1.0896713 120 Ribose 5-phosphate isomerase G ribose 5-phosphate isomerase 0.000000e+00 0 2.394031e-03 -1.355674e-04 1.380564e-02 -4.437955e-02 2.330303e-01 0 47 TRUE TRUE 79 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5077392 0.5695312 U 0.4686274 0.6162291 13773 129 182709 182710 1 21 Same - - 0.000000 0 0.000000 -0.65730196 1.454341 3.190910 1.0896713 120 Ribose 5-phosphate isomerase G ribose 5-phosphate isomerase 1.460523 3.128197 1.0150979 517 FOG: CBS domain R conserved protein with 2 CBS domains 3.631628e-03 8 3.821733e-05 2.691976e-05 2.124207e-02 2.294840e-02 3.864392e-03 47 8 FALSE TRUE 78 TRUE 0.4469764 0.2268782 0.5480306 0.4469764 0.7652913 0.5314351 0.5174784 0.6474175 U 0.4686274 0.5340541 13773 129 182710 182711 1 97 Divergent - + 0.000000 0 0.000000 0.00000000 1.460523 3.128197 1.0150979 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.349174 2.866050 1.0095203 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 3.137307e-03 2 1.239863e-02 -9.332967e-04 3.614812e-02 -1.453874e-01 9.380584e-01 8 2 FALSE TRUE 77 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5183257 0.4784126 0.4437091 U 0.4686274 0.6162291 13773 129 182711 182712 1 944 Same + + 0.000000 0 0.000000 0.00000000 1.349174 2.866050 1.0095203 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 1.565279 3.517519 1.0823076 - - - conserved within P. aerophilum 0.000000e+00 0 4.670113e-02 -1.164125e-02 -1.089723e-01 -6.212006e-01 2.484918e+00 2 0 TRUE TRUE 78 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3921807 0.4034139 U 0.4686274 0.6162291 13773 129 182712 182713 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.565279 3.517519 1.0823076 - - - conserved within P. aerophilum 1.514512 3.424481 1.1040097 - - - conserved within P. aerophilum part 1, authentic frameshift 0.000000e+00 0 2.577288e-03 7.188319e-03 8.196554e-02 4.683365e-01 4.136213e-02 0 0 TRUE TRUE 79 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6631244 0.6275054 U 0.4686274 0.6162291 13773 129 182713 182714 1 -16 Same + + 0.000000 0 0.000000 0.00000000 1.514512 3.424481 1.1040097 - - - conserved within P. aerophilum part 1, authentic frameshift 1.369124 2.969132 1.0044779 - - - conserved within P. aerophilum part 2, authentic frameshift 0.000000e+00 0 2.113767e-02 -5.192731e-03 -3.290651e-02 -3.931491e-01 1.578369e+00 0 0 TRUE TRUE 80 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4207962 0.4149007 U 0.4686274 0.6162291 13773 129 182714 182715 1 3 Convergent + - 0.000000 0 0.000000 0.00000000 1.369124 2.969132 1.0044779 - - - conserved within P. aerophilum part 2, authentic frameshift 1.498859 3.122022 1.0387892 1433 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 1.683129e-02 -3.905007e-03 -3.638713e-02 -3.328219e-01 1.359023e+00 0 0 TRUE TRUE 81 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4314264 0.4219096 U 0.4686274 0.6162291 13773 129 182715 182716 1 40 Divergent - + 0.000000 0 0.000000 0.00000000 1.498859 3.122022 1.0387892 1433 Uncharacterized conserved protein S hypothetical protein 1.606924 3.638847 1.1331859 - - - conserved within P. aerophilum 0.000000e+00 0 1.167795e-02 7.382448e-03 1.627640e-01 4.386500e-01 1.431545e-01 0 0 FALSE TRUE 80 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6511397 0.5946095 U 0.4686274 0.6162291 13773 129 182716 182717 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.606924 3.638847 1.1331859 - - - conserved within P. aerophilum 1.530341 3.485590 1.1496562 - - - conserved within P. aerophilum 0.000000e+00 0 5.864819e-03 1.227894e-02 1.187047e-01 5.969953e-01 3.920582e-02 0 0 TRUE TRUE 81 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7193180 0.6283810 U 0.4686274 0.6162291 13773 129 182717 182718 1 133 Convergent + - 0.000000 0 0.000000 0.00000000 1.530341 3.485590 1.1496562 - - - conserved within P. aerophilum 1.706809 3.556574 1.1178929 1433 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 3.114076e-02 2.016475e-02 4.063521e-01 6.596172e-01 8.415788e-02 0 0 TRUE TRUE 82 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7391690 0.6127540 U 0.4686274 0.6162291 13773 129 182718 182719 1 28 Same - - 0.000000 0 0.000000 0.00000000 1.706809 3.556574 1.1178929 1433 Uncharacterized conserved protein S hypothetical protein 1.409154 3.095665 1.0528530 1052 Lactate dehydrogenase and related dehydrogenases CHR D-3-phosphoglycerate dehydrogenase (serA) 0.000000e+00 0 8.859864e-02 -1.078856e-02 -2.665452e-01 -3.119409e-01 1.668320e+00 0 26 FALSE TRUE 81 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4368493 0.4129302 U 0.4686274 0.6162291 13773 129 182719 182720 1 91 Divergent - + 0.000000 0 0.000000 -0.51148869 1.409154 3.095665 1.0528530 1052 Lactate dehydrogenase and related dehydrogenases CHR D-3-phosphoglycerate dehydrogenase (serA) 1.473242 3.278669 1.0770033 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C pyruvate ferredoxin oxidoreductase gamma subunit (porG) 1.755773e-02 16 4.107274e-03 -9.228779e-04 6.628586e-03 -9.600079e-02 3.845332e-01 26 16 FALSE TRUE 80 FALSE 0.4469764 0.2340629 0.5480306 0.4469764 0.7783446 0.6580649 0.4934796 0.5154995 U 0.4686274 0.5363313 13773 129 182720 182721 1 -3 Same + + 19.048712 0 29.442822 29.44282200 1.473242 3.278669 1.0770033 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C pyruvate ferredoxin oxidoreductase gamma subunit (porG) 1.491217 3.106869 0.9472652 1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit C pyruvate ferredoxin oxidoreductase delta subunit (porD) 1.926718e-01 8 3.231233e-04 8.701211e-04 3.372674e-02 1.340345e-01 2.262681e-02 C 16 8 TRUE TRUE 81 TRUE 2.4102042 1.9689678 0.5480306 2.4371546 0.7652913 1.1363677 0.5258020 0.6365095 Y 1.4497162 0.9271186 13773 129 182721 182722 1 0 Same + + 19.048712 0 29.442822 29.44282200 1.491217 3.106869 0.9472652 1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit C pyruvate ferredoxin oxidoreductase delta subunit (porD) 1.397423 2.985232 1.0640363 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C pyruvate ferredoxin oxidoreductase alpha subunit (porA) 2.749196e-01 8 8.797427e-03 -2.149332e-03 -1.023540e-03 -2.008795e-01 8.035203e-01 C 8 10 TRUE TRUE 82 TRUE 2.4102042 1.9689678 0.5480306 2.4371546 0.7652913 1.2035108 0.4642425 0.4550988 Y 1.4497162 0.9271186 13773 129 182722 182723 1 -3 Same + + 21.014824 0 29.511815 29.51181487 1.397423 2.985232 1.0640363 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C pyruvate ferredoxin oxidoreductase alpha subunit (porA) 1.398827 3.019774 1.0637480 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C pyruvate ferredoxin oxidoreductase beta subunit (porB) 2.561589e-01 10 1.973248e-06 2.836957e-03 5.352814e-02 1.933250e-01 2.355978e-04 C 10 11 TRUE TRUE 83 TRUE 2.3380363 1.9721625 0.5480306 2.4272596 0.7739415 1.1936934 0.5474130 0.6542630 Y 1.4497162 0.9279933 13773 129 182723 182724 1 94 Same + + 0.000000 0 0.000000 0.00000000 1.398827 3.019774 1.0637480 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C pyruvate ferredoxin oxidoreductase beta subunit (porB) 1.356625 2.994717 1.0638980 - - - hypothetical protein 0.000000e+00 0 1.781018e-03 4.981487e-03 9.477268e-02 3.199977e-01 9.518385e-02 11 0 TRUE TRUE 84 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5994935 0.6086719 U 0.4686274 0.6162291 13773 129 182724 182725 1 47 Same + + 0.000000 0 0.000000 0.00000000 1.356625 2.994717 1.0638980 - - - hypothetical protein 1.446952 2.887522 1.0325492 - - - hypothetical protein 0.000000e+00 0 8.158888e-03 4.208542e-04 2.901508e-03 -4.092333e-02 6.333863e-01 0 0 TRUE TRUE 85 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5088239 0.4724827 U 0.4686274 0.6162291 13773 129 182725 182726 1 183 Same + + 0.000000 0 0.000000 0.00000000 1.446952 2.887522 1.0325492 - - - hypothetical protein 1.369313 2.976423 1.0386061 1449 Alpha-amylase/alpha-mannosidase G hypothetical protein 0.000000e+00 0 6.027848e-03 3.645108e-04 4.205862e-02 -3.664016e-02 5.160156e-01 0 0 TRUE TRUE 86 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5101574 0.4905939 U 0.4686274 0.6162291 13773 129 182726 182727 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.369313 2.976423 1.0386061 1449 Alpha-amylase/alpha-mannosidase G hypothetical protein 1.404792 3.418913 1.1918067 477 Permeases of the major facilitator superfamily GEPR hypothetical protein 0.000000e+00 0 1.258749e-03 3.825039e-03 5.386707e-02 2.417233e-01 8.912722e-02 0 0 TRUE TRUE 87 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5656240 0.6113614 U 0.4686274 0.6162291 13773 129 182727 182728 1 226 Same + + 0.000000 0 0.000000 0.00000000 1.404792 3.418913 1.1918067 477 Permeases of the major facilitator superfamily GEPR hypothetical protein 1.386069 3.066625 1.0697039 31 Cysteine synthase E cysteine synthase 0.000000e+00 0 3.505408e-04 3.044183e-03 6.165279e-02 1.972395e-01 3.115780e-02 0 40 TRUE TRUE 88 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5488427 0.6322033 U 0.4686274 0.6162291 13773 129 182728 182729 1 243 Convergent + - 0.000000 0 0.000000 0.00000000 1.386069 3.066625 1.0697039 31 Cysteine synthase E cysteine synthase 1.403003 3.211531 1.0905413 - - - hypothetical protein 0.000000e+00 0 2.867620e-04 3.161027e-03 5.280713e-02 2.092815e-01 2.379596e-02 40 0 TRUE TRUE 89 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5536384 0.6358881 U 0.4686274 0.6162291 13773 129 182729 182730 1 39 Same - - 0.000000 0 0.000000 0.00000000 1.403003 3.211531 1.0905413 - - - hypothetical protein 1.400545 3.089340 1.0271518 476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 H thiF/moeB/hesA family protein 0.000000e+00 0 6.039088e-06 2.460505e-03 5.012592e-02 1.603007e-01 7.633367e-04 0 26 FALSE TRUE 88 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5348472 0.6522016 U 0.4686274 0.6162291 13773 129 182730 182731 1 196 Divergent - + 0.000000 0 0.000000 -2.88741881 1.400545 3.089340 1.0271518 476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 H thiF/moeB/hesA family protein 1.420262 3.060212 1.0600504 584 Glycerophosphoryl diester phosphodiesterase C glycerophosphoryl diester phosphodiesterase 2.662582e-04 26 3.887540e-04 1.582910e-03 3.514078e-02 9.032818e-02 3.860034e-02 0 26 33 FALSE TRUE 87 FALSE 0.4469764 0.1920291 0.5480306 0.4469764 0.7764129 0.4459260 0.5178383 0.6286000 N 0.5492530 0.5318098 13773 129 182731 182732 1 652 Same + + 0.000000 0 0.000000 0.00000000 1.420262 3.060212 1.0600504 584 Glycerophosphoryl diester phosphodiesterase C glycerophosphoryl diester phosphodiesterase 1.605405 3.720598 1.1115991 1195 Recombinational DNA repair ATPase (RecF pathway) L partial recF homolog 0.000000e+00 0 3.427793e-02 -4.794496e-03 2.245475e-02 -1.905256e-01 1.192672e+00 0 33 0 TRUE TRUE 88 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4672140 0.4285596 N 0.5492530 0.6245624 13773 129 182732 182733 1 643 Same + + 0.000000 0 0.000000 0.00000000 1.605405 3.720598 1.1115991 1195 Recombinational DNA repair ATPase (RecF pathway) L partial recF homolog 1.401837 3.362028 1.1693107 4986 ABC-type anion transport system, duplicated permease component P sulfonate transport permease protein, putative 0.000000e+00 0 4.143998e-02 -7.632194e-03 -1.225003e-01 -3.495205e-01 1.623033e+00 0 0 0 TRUE TRUE 89 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4280275 0.4140690 N 0.5492530 0.6245624 13773 129 182733 182734 1 -39 Same + + 0.000000 0 0.000000 0.00000000 1.401837 3.362028 1.1693107 4986 ABC-type anion transport system, duplicated permease component P sulfonate transport permease protein, putative 1.350582 3.007226 1.0209557 1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component P taurine(sulfate) transport ATP-binding protein, putative 0.000000e+00 0 2.627054e-03 4.995736e-03 9.872120e-02 3.093210e-01 1.396912e-01 P 0 38 TRUE TRUE 90 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5958996 0.5958874 Y 1.4497162 0.7118045 13773 129 182734 182735 1 58 Same + + 0.000000 0 0.000000 0.00000000 1.350582 3.007226 1.0209557 1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component P taurine(sulfate) transport ATP-binding protein, putative 1.497088 3.358887 1.1544612 - - - P. aerophilum family 59 protein 0.000000e+00 0 2.146386e-02 -4.606534e-03 -5.362903e-02 -3.752224e-01 1.584159e+00 38 0 TRUE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4241395 0.4148168 U 0.4686274 0.6162291 13773 129 182735 182736 1 -19 Same + + 0.000000 0 0.000000 0.00000000 1.497088 3.358887 1.1544612 - - - P. aerophilum family 59 protein 1.542961 3.620894 1.1577112 - - - P. aerophilum family 3 protein 0.000000e+00 0 2.104363e-03 4.184212e-03 8.565126e-02 3.510265e-01 5.696813e-02 0 0 TRUE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6131154 0.6214366 U 0.4686274 0.6162291 13773 129 182736 182737 1 66 Convergent + - 0.000000 0 0.000000 0.00000000 1.542961 3.620894 1.1577112 - - - P. aerophilum family 3 protein 1.429811 3.103309 1.0366692 4754 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 1.280290e-02 -1.976189e-03 -2.247882e-02 -8.664579e-02 7.113880e-01 0 2 TRUE TRUE 93 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4963411 0.4636452 U 0.4686274 0.6162291 13773 129 182737 182738 1 76 Same - - 0.000000 0 0.000000 0.00000000 1.429811 3.103309 1.0366692 4754 Uncharacterized conserved protein S hypothetical protein 1.476399 3.068366 1.0652576 361 Translation initiation factor 1 (IF-1) J translation initiation factor aIF-1A 2.318180e-03 2 2.170426e-03 -5.396745e-04 1.483284e-02 -3.950974e-02 2.022583e-01 2 6 FALSE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5012279 0.5092261 0.5792906 U 0.4686274 0.6162291 13773 129 182738 182739 1 51 Same - - 0.000000 0 0.000000 0.00000000 1.476399 3.068366 1.0652576 361 Translation initiation factor 1 (IF-1) J translation initiation factor aIF-1A 1.549524 3.379409 1.1006363 - - - hypothetical protein 0.000000e+00 0 5.347184e-03 2.453881e-03 7.229570e-02 2.444032e-01 1.685849e-01 6 0 FALSE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5676432 0.5880602 U 0.4686274 0.6162291 13773 129 182739 182740 1 -49 Same - - 0.000000 0 0.000000 0.00000000 1.549524 3.379409 1.1006363 - - - hypothetical protein 1.552175 3.276414 1.0706485 - - - hypothetical protein 0.000000e+00 0 7.031621e-06 9.889848e-03 1.377121e-01 5.547385e-01 7.126832e-05 0 0 FALSE TRUE 90 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7012158 0.6552829 U 0.4686274 0.6162291 13773 129 182740 182741 1 176 Divergent - + 0.000000 0 0.000000 0.00000000 1.552175 3.276414 1.0706485 - - - hypothetical protein 1.439088 3.033542 1.0392420 - - - paREP2b 0.000000e+00 0 1.278865e-02 -1.240076e-03 -1.917118e-02 -1.667090e-02 5.948991e-01 0 0 FALSE TRUE 89 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5163968 0.4773691 U 0.4686274 0.6162291 13773 129 182741 182742 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.439088 3.033542 1.0392420 - - - paREP2b 1.348284 2.953619 1.0169013 675 Transposase and inactivated derivatives L hypothetical protein 0.000000e+00 0 8.245482e-03 1.268705e-03 6.218603e-02 1.755910e-02 5.878170e-01 0 0 TRUE TRUE 90 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178366 0.4784697 U 0.4686274 0.6162291 13773 129 182742 182743 1 168 Same + + 0.000000 0 0.000000 0.00000000 1.348284 2.953619 1.0169013 675 Transposase and inactivated derivatives L hypothetical protein 1.492964 3.322962 1.1520251 - - - P. aerophilum family 66 protein 0.000000e+00 0 2.093227e-02 -4.286326e-03 -5.198940e-02 -3.602643e-01 1.551487e+00 0 0 TRUE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4259926 0.4155777 U 0.4686274 0.6162291 13773 129 182743 182744 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.492964 3.322962 1.1520251 - - - P. aerophilum family 66 protein 1.604045 3.866662 1.1900898 - - - P. aerophilum family 79 protein 0.000000e+00 0 1.233914e-02 6.345880e-03 1.497245e-01 3.981131e-01 1.723875e-01 0 0 TRUE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6338990 0.5871112 U 0.4686274 0.6162291 13773 129 182744 182745 1 33 Same + + 0.000000 0 0.000000 0.00000000 1.604045 3.866662 1.1900898 - - - P. aerophilum family 79 protein 1.408824 3.210589 1.1297077 - - - P. aerophilum family 68 protein 0.000000e+00 0 3.811136e-02 -6.498239e-03 -1.098173e-01 -2.823592e-01 1.429704e+00 0 0 TRUE TRUE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4448920 0.4190403 U 0.4686274 0.6162291 13773 129 182745 182746 1 80 Same + + 0.000000 0 0.000000 0.00000000 1.408824 3.210589 1.1297077 - - - P. aerophilum family 68 protein 1.423295 3.498138 1.1029672 - - - P. aerophilum family 70 protein 0.000000e+00 0 2.094213e-04 1.196076e-03 3.212555e-02 6.164180e-02 1.783239e-02 0 0 TRUE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184341 0.6388731 U 0.4686274 0.6162291 13773 129 182746 182747 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.423295 3.498138 1.1029672 - - - P. aerophilum family 70 protein 1.423804 3.164891 1.0578578 1533 DNA repair photolyase L conserved hypothetical protein 0.000000e+00 0 2.584281e-07 7.751834e-04 2.972946e-02 3.549516e-02 1.472486e-05 0 7 TRUE TRUE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176096 0.6556702 U 0.4686274 0.6162291 13773 129 182747 182748 1 10 Same - - 0.000000 0 0.000000 0.00000000 1.423804 3.164891 1.0578578 1533 DNA repair photolyase L conserved hypothetical protein 1.408704 3.043933 1.0620728 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 0.000000e+00 0 2.280066e-04 1.177750e-03 3.720318e-02 6.068527e-02 1.929605e-02 0 7 0 FALSE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185056 0.6380078 N 0.5492530 0.6245624 13773 129 182748 182749 1 -30 Same - - 0.000000 0 0.000000 0.00000000 1.408704 3.043933 1.0620728 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 1.486801 3.266287 1.0613737 - - - hypothetical protein 0.000000e+00 0 6.099198e-03 -1.511548e-03 1.620295e-03 -1.378530e-01 5.610619e-01 0 0 FALSE TRUE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4797797 0.4821849 U 0.4686274 0.6162291 13773 129 182749 182750 1 133 Same - - 0.000000 0 0.000000 0.00000000 1.486801 3.266287 1.0613737 - - - hypothetical protein 1.411744 3.067827 1.0781635 2129 Predicted phosphoesterases, related to the Icc protein R conserved hypothetical protein 0.000000e+00 0 5.633568e-03 -1.403897e-03 5.131177e-03 -1.258233e-01 5.193287e-01 0 7 FALSE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4831907 0.4896794 U 0.4686274 0.6162291 13773 129 182750 182751 1 248 Divergent - + 0.000000 0 0.000000 0.00000000 1.411744 3.067827 1.0781635 2129 Predicted phosphoesterases, related to the Icc protein R conserved hypothetical protein 1.485897 3.336971 1.1473931 - - - P. aerophilum family 59 protein 0.000000e+00 0 5.498714e-03 -1.368063e-03 3.773209e-03 -1.233160e-01 5.072326e-01 7 0 FALSE TRUE 91 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4840294 0.4918136 U 0.4686274 0.6162291 13773 129 182751 182752 1 -22 Same + + 0.000000 0 0.000000 0.00000000 1.485897 3.336971 1.1473931 - - - P. aerophilum family 59 protein 1.437743 3.585480 1.1131465 - - - P. aerophilum family 3 protein 0.000000e+00 0 2.318828e-03 -4.709744e-04 1.268061e-02 -1.625094e-02 2.064213e-01 0 0 TRUE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5166788 0.5777522 U 0.4686274 0.6162291 13773 129 182752 182753 1 603 Same + + 0.000000 0 0.000000 0.00000000 1.437743 3.585480 1.1131465 - - - P. aerophilum family 3 protein 1.521212 3.489115 1.1866354 - - - P. aerophilum family 66 protein 0.000000e+00 0 6.967056e-03 -9.530059e-04 2.150116e-02 -2.466178e-02 4.478619e-01 0 0 TRUE TRUE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5139987 0.5041686 U 0.4686274 0.6162291 13773 129 182753 182754 1 17 Same + + 0.000000 0 0.000000 0.00000000 1.521212 3.489115 1.1866354 - - - P. aerophilum family 66 protein 1.446668 3.597825 1.1322625 - - - P. aerophilum family 79 protein 0.000000e+00 0 5.556887e-03 -3.299137e-04 4.557523e-03 3.143169e-02 3.366315e-01 0 0 TRUE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174075 0.5289643 U 0.4686274 0.6162291 13773 129 182754 182755 1 901 Same + + 0.000000 0 0.000000 0.00000000 1.446668 3.597825 1.1322625 - - - P. aerophilum family 79 protein 1.489166 3.324757 1.0970174 705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) R integral membrane protein (rhomboid related), putative 0.000000e+00 0 1.806119e-03 -1.784880e-04 2.221747e-02 2.178396e-02 1.496140e-01 0 26 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175495 0.5933123 U 0.4686274 0.6162291 13773 129 182755 182756 1 96 Same + + 0.000000 0 0.000000 0.00000000 1.489166 3.324757 1.0970174 705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) R integral membrane protein (rhomboid related), putative 1.526451 3.313851 1.0703465 - - - hypothetical protein 0.000000e+00 0 1.390138e-03 2.835173e-03 6.457067e-02 2.875482e-01 4.919340e-02 26 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5879045 0.6240491 U 0.4686274 0.6162291 13773 129 182756 182757 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.526451 3.313851 1.0703465 - - - hypothetical protein 1.650153 3.914203 1.1667642 - - - hypothetical protein 0.000000e+00 0 1.530236e-02 1.491852e-02 2.811875e-01 6.140090e-01 7.506675e-02 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7242977 0.6163909 U 0.4686274 0.6162291 13773 129 182757 182758 1 80 Convergent + - 0.000000 0 0.000000 0.00000000 1.650153 3.914203 1.1667642 - - - hypothetical protein 1.468636 3.217772 1.0480771 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 3.294867e-02 3.427182e-03 -3.876083e-02 2.375886e-01 4.592325e-01 0 0 TRUE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5638495 0.5023186 U 0.4686274 0.6162291 13773 129 182758 182759 1 165 Divergent - + 0.000000 0 0.000000 0.00000000 1.468636 3.217772 1.0480771 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.428216 3.248849 1.1078638 1585 Membrane protein implicated in regulation of membrane protease activity OU conserved hypothetical protein 0.000000e+00 0 1.633782e-03 -3.996409e-04 1.667414e-02 -3.500276e-02 1.537988e-01 0 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5106866 0.5921731 U 0.4686274 0.6162291 13773 129 182759 182760 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.428216 3.248849 1.1078638 1585 Membrane protein implicated in regulation of membrane protease activity OU conserved hypothetical protein 1.530134 3.545377 1.1779607 500 SAM-dependent methyltransferases QR conserved hypothetical protein 0.000000e+00 0 1.038740e-02 -1.825011e-03 1.378042e-02 -9.320012e-02 6.655454e-01 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4944289 0.4693615 U 0.4686274 0.6162291 13773 129 182760 182761 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.530134 3.545377 1.1779607 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.374226 2.914265 1.0411916 495 Leucyl-tRNA synthetase J leucyl-tRNA synthetase 0.000000e+00 0 2.430736e-02 -6.076219e-03 -5.093056e-02 -4.305950e-01 1.724293e+00 0 12 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4141517 0.4118977 U 0.4686274 0.6162291 13773 129 182761 182762 1 2 Convergent + - 0.000000 0 0.000000 -0.56248240 1.374226 2.914265 1.0411916 495 Leucyl-tRNA synthetase J leucyl-tRNA synthetase 1.415167 3.134178 1.1263163 1110 Reverse gyrase L reverse gyrase 9.541988e-02 9 1.676146e-03 2.795452e-03 4.163350e-02 1.646392e-01 1.408409e-01 0 12 9 TRUE TRUE 100 FALSE 0.4469764 0.2322970 0.5480306 0.4469764 0.7702221 0.9963746 0.5362258 0.5955598 N 0.5492530 0.5445608 13773 129 182762 182763 1 438 Divergent - + 0.000000 0 0.000000 0.00000000 1.415167 3.134178 1.1263163 1110 Reverse gyrase L reverse gyrase 1.308759 2.716740 0.9035618 - - - hypothetical protein 0.000000e+00 0 1.132271e-02 5.167082e-03 1.294851e-01 2.404888e-01 4.458099e-01 9 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5650280 0.5046098 U 0.4686274 0.6162291 13773 129 182763 182764 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.308759 2.716740 0.9035618 - - - hypothetical protein 1.448597 3.097677 1.0341256 2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 R conserved hypothetical protein 0.000000e+00 0 1.955486e-02 3.987504e-04 -2.624532e-02 -6.403547e-02 9.923401e-01 0 23 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5027918 0.4398511 U 0.4686274 0.6162291 13773 129 182764 182765 1 131 Divergent - + 0.000000 0 0.000000 -0.27723266 1.448597 3.097677 1.0341256 2110 Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 R conserved hypothetical protein 1.400700 3.060366 1.0513164 1032 Fe-S oxidoreductase C hypothetical protein 3.242514e-02 2 2.294107e-03 1.417165e-04 2.890067e-02 -2.846610e-02 2.315508e-01 23 2 FALSE TRUE 99 FALSE 0.4469764 0.2571217 0.5480306 0.4469764 0.6838149 0.7502724 0.5126666 0.5704308 U 0.4686274 0.5436291 13773 129 182765 182766 1 82 Same + + 0.000000 0 0.000000 0.00000000 1.400700 3.060366 1.0513164 1032 Fe-S oxidoreductase C hypothetical protein 1.382614 2.994419 1.0212858 417 DNA polymerase elongation subunit (family B) L possible DNA-directed DNA polymerase (B2) 0.000000e+00 0 3.271033e-04 3.486548e-03 6.699063e-02 2.324731e-01 2.309094e-02 0 2 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5621143 0.6362005 N 0.5492530 0.6245624 13773 129 182766 182767 1 39 Same + + 0.000000 0 0.000000 0.00000000 1.382614 2.994419 1.0212858 417 DNA polymerase elongation subunit (family B) L possible DNA-directed DNA polymerase (B2) 1.464245 3.366553 1.0934311 - - - hypothetical protein 0.000000e+00 0 6.663477e-03 -8.839185e-04 -1.190976e-03 -1.207821e-01 6.056017e-01 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4847443 0.4761308 U 0.4686274 0.6162291 13773 129 182767 182768 1 -23 Convergent + - 0.000000 0 0.000000 0.00000000 1.464245 3.366553 1.0934311 - - - hypothetical protein 1.252314 2.896666 1.1504068 - - - hypothetical protein 0.000000e+00 0 4.491471e-02 -2.558502e-03 9.105072e-02 -2.113277e-01 1.442580e+00 0 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4611764 0.4187637 U 0.4686274 0.6162291 13773 129 182768 182769 1 45 Same - - 0.000000 0 0.000000 0.00000000 1.252314 2.896666 1.1504068 - - - hypothetical protein 1.402844 3.000575 0.9637167 - - - paREP1, authentic frameshift 0.000000e+00 0 2.265932e-02 9.665121e-03 3.908346e-02 3.832681e-01 3.583442e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6264635 0.5224252 U 0.4686274 0.6162291 13773 129 182769 182770 1 73 Same - - 0.000000 0 0.000000 0.00000000 1.402844 3.000575 0.9637167 - - - paREP1, authentic frameshift 1.378027 3.063042 1.0616944 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 0.000000e+00 0 6.158838e-04 3.561860e-03 7.006742e-02 2.327623e-01 4.454270e-02 0 2 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5623052 0.6261253 U 0.4686274 0.6162291 13773 129 182770 182771 1 485 Divergent - + 0.000000 0 0.000000 0.00000000 1.378027 3.063042 1.0616944 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.499093 3.332686 1.1280361 705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) R integral membrane protein (rhomboid related), putative 0.000000e+00 0 1.465705e-02 -3.499576e-03 -2.807130e-02 -3.013030e-01 1.214563e+00 2 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4402131 0.4277879 U 0.4686274 0.6162291 13773 129 182771 182772 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.499093 3.332686 1.1280361 705 Uncharacterized membrane protein (homolog of Drosophila rhomboid) R integral membrane protein (rhomboid related), putative 1.381853 3.091054 1.0379766 - - - hypothetical protein 0.000000e+00 0 1.374527e-02 -3.317072e-03 -1.154400e-02 -2.870288e-01 1.152780e+00 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4432972 0.4304608 U 0.4686274 0.6162291 13773 129 182772 182773 1 133 Same + + 0.000000 0 0.000000 0.00000000 1.381853 3.091054 1.0379766 - - - hypothetical protein 1.472582 3.280016 1.1227029 667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) C conserved hypothetical protein 0.000000e+00 0 8.231700e-03 -1.473461e-03 -7.630897e-03 -1.656441e-01 7.414756e-01 0 4 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4734249 0.4605849 U 0.4686274 0.6162291 13773 129 182773 182774 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.472582 3.280016 1.1227029 667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) C conserved hypothetical protein 1.452862 3.339382 1.1627268 2245 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 3.888459e-04 3.113661e-05 1.996709e-02 3.295070e-02 3.115780e-02 4 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174873 0.6322033 U 0.4686274 0.6162291 13773 129 182774 182775 1 25 Same - - 0.000000 0 0.000000 0.00000000 1.452862 3.339382 1.1627268 2245 Predicted membrane protein S conserved hypothetical protein 1.381880 3.087929 1.0385853 - - - hypothetical protein 0.000000e+00 0 5.038425e-03 -1.021480e-04 3.180869e-02 -6.476818e-02 4.675915e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5027134 0.4996268 U 0.4686274 0.6162291 13773 129 182775 182776 1 73 Divergent - + 0.000000 0 0.000000 0.00000000 1.381880 3.087929 1.0385853 - - - hypothetical protein 1.355417 2.908650 1.0147385 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 0.000000e+00 0 7.002936e-04 6.671480e-03 1.098638e-01 4.266823e-01 3.170203e-02 0 1 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6463129 0.6317872 U 0.4686274 0.6162291 13773 129 182776 182777 1 344 Convergent + - 0.000000 0 0.000000 0.00000000 1.355417 2.908650 1.0147385 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 1.384111 3.325076 1.1348392 - - - hypothetical protein 0.000000e+00 0 8.233017e-04 6.457438e-03 8.434382e-02 4.157711e-01 3.710724e-02 1 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6418935 0.6290639 U 0.4686274 0.6162291 13773 129 182777 182778 1 390 Same - - 0.000000 0 0.000000 0.00000000 1.384111 3.325076 1.1348392 - - - hypothetical protein 1.434671 3.251517 1.1101294 1798 Diphthamide biosynthesis methyltransferase J diphthine synthase (dph5) 0.000000e+00 0 2.556319e-03 1.125102e-03 2.310674e-02 3.582028e-02 2.412521e-01 0 12 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176997 0.5655296 U 0.4686274 0.6162291 13773 129 182778 182779 1 43 Divergent - + 0.000000 0 0.000000 0.00000000 1.434671 3.251517 1.1101294 1798 Diphthamide biosynthesis methyltransferase J diphthine synthase (dph5) 1.530303 3.419668 1.0994041 - - - hypothetical protein 0.000000e+00 0 9.145594e-03 -1.319552e-03 2.041217e-02 -4.378584e-02 5.530428e-01 12 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5078759 0.4833863 U 0.4686274 0.6162291 13773 129 182779 182780 1 1 Convergent + - 0.000000 0 0.000000 0.00000000 1.530303 3.419668 1.0994041 - - - hypothetical protein 1.400296 3.024883 1.0344918 - - - hypothetical protein 0.000000e+00 0 1.690194e-02 -4.032088e-03 -3.558937e-02 -2.851292e-01 1.207806e+00 0 0 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4438318 0.4278978 U 0.4686274 0.6162291 13773 129 182780 182781 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.400296 3.024883 1.0344918 - - - hypothetical protein 1.487798 3.312719 1.1020946 101 Pseudouridylate synthase J tRNA pseudouridine synthase A 0.000000e+00 0 7.656713e-03 -1.860219e-03 -4.277137e-03 -1.804208e-01 7.217826e-01 0 57 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4702327 0.4627534 U 0.4686274 0.6162291 13773 129 182781 182782 1 27 Divergent - + 0.000000 0 0.000000 0.00000000 1.487798 3.312719 1.1020946 101 Pseudouridylate synthase J tRNA pseudouridine synthase A 1.501038 3.332284 1.1261665 454 Histone acetyltransferase HPA2 and related acetyltransferases KR conserved protein (acetyltransferase) 0.000000e+00 0 1.752808e-04 1.807359e-03 4.476299e-02 2.203310e-01 6.870031e-03 57 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5571308 0.6445676 U 0.4686274 0.6162291 13773 129 182782 182783 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.501038 3.332284 1.1261665 454 Histone acetyltransferase HPA2 and related acetyltransferases KR conserved protein (acetyltransferase) 1.550055 3.115371 1.0309009 - - - hypothetical protein 0.000000e+00 0 2.402676e-03 4.898082e-03 9.646861e-02 3.800710e-01 5.230506e-02 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6250051 0.6231515 U 0.4686274 0.6162291 13773 129 182783 182784 1 111 Convergent + - 0.000000 0 0.000000 0.00000000 1.550055 3.115371 1.0309009 - - - hypothetical protein 1.460413 3.292077 1.1529629 2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases I conserved protein (3-hydroxyisobutyrate dehydrogenase family) 0.000000e+00 0 8.035761e-03 8.899032e-04 6.629171e-03 1.371214e-01 3.095902e-01 0 40 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5268464 0.5385067 U 0.4686274 0.6162291 13773 129 182784 182785 1 45 Divergent - + 0.000000 0 0.000000 -3.80211706 1.460413 3.292077 1.1529629 2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases I conserved protein (3-hydroxyisobutyrate dehydrogenase family) 1.398518 3.052253 1.0454617 1156 Archaeal/vacuolar-type H+-ATPase subunit B C H+-transporting ATP synthase subunit B (atpB) 1.171292e-03 40 3.830901e-03 -4.769130e-04 2.205464e-02 -8.034237e-02 3.835820e-01 0 40 46 FALSE TRUE 99 FALSE 0.4469764 0.1852950 0.5480306 0.4469764 0.7733221 0.4770312 0.4978615 0.5159995 N 0.5492530 0.5296729 13773 129 182785 182786 1 202 Same + + 0.000000 0 0.000000 -0.13150953 1.398518 3.052253 1.0454617 1156 Archaeal/vacuolar-type H+-ATPase subunit B C H+-transporting ATP synthase subunit B (atpB) 1.450152 2.893411 0.9949132 - - - conserved hypothetical protein 1.307697e-02 2 2.666045e-03 6.560696e-05 1.440894e-02 -3.667079e-02 2.691563e-01 46 2 TRUE TRUE 100 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.6236374 0.5100912 0.5538632 U 0.4686274 0.5537552 13773 129 182786 182787 1 295 Same + + 0.000000 0 0.000000 0.00000000 1.450152 2.893411 0.9949132 - - - conserved hypothetical protein 1.439250 3.257969 1.0375586 - - - hypothetical protein 0.000000e+00 0 1.188651e-04 1.506749e-05 2.128443e-02 -1.360577e-03 1.010773e-02 2 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199831 0.6427221 U 0.4686274 0.6162291 13773 129 182787 182788 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.439250 3.257969 1.0375586 - - - hypothetical protein 1.572674 3.455932 1.1343620 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 1.780196e-02 -1.472751e-03 4.049703e-02 -1.306154e-02 6.831917e-01 0 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173725 0.4664146 U 0.4686274 0.6162291 13773 129 182788 182789 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.572674 3.455932 1.1343620 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.407165 3.121759 1.0520501 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 2.739300e-02 -5.363958e-03 -7.436535e-02 -2.724264e-01 1.314657e+00 0 2 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4468044 0.4236245 U 0.4686274 0.6162291 13773 129 182789 182790 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.407165 3.121759 1.0520501 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.371745 2.928486 0.9696957 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 7.508473e-04 2 1.254597e-03 3.522641e-03 7.306802e-02 2.177347e-01 9.708748e-02 2 2 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4618072 0.5564194 0.6079718 U 0.4686274 0.6162291 13773 129 182790 182791 1 417 Divergent - + 0.000000 0 0.000000 -0.07232066 1.371745 2.928486 0.9696957 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 1.424476 3.225836 1.1062907 11 Uncharacterized conserved protein S conserved hypothetical protein 9.573095e-03 2 2.780560e-03 2.143876e-03 3.153430e-02 1.138385e-01 2.227724e-01 2 11 FALSE TRUE 99 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6838149 0.5921126 0.5206651 0.5732362 U 0.4686274 0.5573725 13773 129 182791 182792 1 75 Convergent + - 0.000000 0 0.000000 0.00000000 1.424476 3.225836 1.1062907 11 Uncharacterized conserved protein S conserved hypothetical protein 1.314289 2.779749 0.9469888 1694 Predicted pyrophosphatase R hypothetical protein 0.000000e+00 0 1.214120e-02 3.690417e-03 1.097836e-01 1.598325e-01 5.383032e-01 11 0 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5345734 0.4854242 U 0.4686274 0.6162291 13773 129 182792 182793 1 79 Divergent - + 0.000000 0 0.000000 0.00000000 1.314289 2.779749 0.9469888 1694 Predicted pyrophosphatase R hypothetical protein 1.428753 2.994897 1.0735770 1716 FOG: FHA domain T hypothetical protein with conserved Forkhead-associated (FHA) domain 0.000000e+00 0 1.310193e-02 3.104081e-03 1.059674e-02 1.207468e-01 6.032151e-01 0 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5221243 0.4767123 U 0.4686274 0.6162291 13773 129 182793 182794 1 20 Same + + 0.000000 0 0.000000 0.00000000 1.428753 2.994897 1.0735770 1716 FOG: FHA domain T hypothetical protein with conserved Forkhead-associated (FHA) domain 1.257718 2.850538 1.0465743 - - - hypothetical protein 0.000000e+00 0 2.925296e-02 4.384874e-03 1.659624e-01 1.306307e-01 7.243930e-01 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5243052 0.4624347 U 0.4686274 0.6162291 13773 129 182794 182795 1 -14 Convergent + - 0.000000 0 0.000000 0.00000000 1.257718 2.850538 1.0465743 - - - hypothetical protein 1.304664 2.806678 0.9725268 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR conserved hypothetical protein 0.000000e+00 0 2.204001e-03 2.841769e-02 3.124217e-01 9.181904e-01 2.565660e-03 0 11 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8070764 0.6491703 U 0.4686274 0.6162291 13773 129 182795 182796 1 67 Divergent - + 9.112948 0 11.703215 10.34996264 1.304664 2.806678 0.9725268 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR conserved hypothetical protein 1.417315 3.009727 1.0459547 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR conserved hypothetical protein 1.046714e-01 11 1.269011e-02 5.000233e-03 2.747726e-02 2.256084e-01 4.781462e-01 11 22 FALSE TRUE 100 FALSE 2.6966212 1.8474056 0.5480306 2.7112802 0.7764261 1.0240303 0.5600448 0.4970610 U 0.4686274 0.8723904 13773 129 182796 182797 1 50 Same + + 0.000000 0 0.000000 0.00000000 1.417315 3.009727 1.0459547 1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes HR conserved hypothetical protein 1.405502 3.173813 1.0920509 500 SAM-dependent methyltransferases QR hypothetical protein 0.000000e+00 0 1.395413e-04 1.563876e-03 4.142193e-02 8.627296e-02 1.325237e-02 22 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176892 0.6413470 U 0.4686274 0.6162291 13773 129 182797 182798 1 143 Same + + 0.000000 0 0.000000 0.00000000 1.405502 3.173813 1.0920509 500 SAM-dependent methyltransferases QR hypothetical protein 1.419142 3.113290 1.0236291 1427 Predicted periplasmic solute-binding protein R conserved hypothetical protein 0.000000e+00 0 1.860395e-04 1.480039e-03 3.533604e-02 8.161695e-02 1.642646e-02 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177307 0.6394805 U 0.4686274 0.6162291 13773 129 182798 182799 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.419142 3.113290 1.0236291 1427 Predicted periplasmic solute-binding protein R conserved hypothetical protein 1.365321 2.997813 1.0577525 1131 ABC-type multidrug transport system, ATPase component V ABC transporter ATP-binding protein, putative 0.000000e+00 0 2.896690e-03 2.775936e-03 6.936701e-02 1.586704e-01 2.162999e-01 0 5 TRUE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5340277 0.5752540 U 0.4686274 0.6162291 13773 129 182799 182800 1 59 Same - - 2.793208 0 2.793208 2.79320801 1.365321 2.997813 1.0577525 1131 ABC-type multidrug transport system, ATPase component V ABC transporter ATP-binding protein, putative 1.387205 3.404527 1.1617673 1668 ABC-type Na+ efflux pump, permease component CP conserved hypothetical protein 3.777386e-02 1 4.789434e-04 5.524749e-03 7.698369e-02 3.668587e-01 2.722627e-02 5 1 FALSE TRUE 102 TRUE 2.9180123 1.7201207 0.5480306 2.9337967 0.6329203 0.7874252 0.6184155 0.6344003 U 0.4686274 0.8497495 13773 129 182800 182801 1 30 Divergent - + 0.000000 0 0.000000 0.00000000 1.387205 3.404527 1.1617673 1668 ABC-type Na+ efflux pump, permease component CP conserved hypothetical protein 1.402212 3.119285 1.0767721 2407 L-fucose isomerase and related proteins G conserved hypothetical protein 1.851224e-04 1 2.252037e-04 3.156775e-03 5.332715e-02 2.089958e-01 1.783239e-02 1 1 FALSE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4421536 0.5534679 0.6388731 U 0.4686274 0.6162291 13773 129 182801 182802 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.402212 3.119285 1.0767721 2407 L-fucose isomerase and related proteins G conserved hypothetical protein 1.419928 3.045347 1.0387963 1052 Lactate dehydrogenase and related dehydrogenases CHR 2-hydroxyacid dehydrogenase 5.631536e-04 1 3.138638e-04 1.547439e-03 3.520252e-02 8.705632e-02 3.061829e-02 1 3 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.5177030 0.6326945 U 0.4686274 0.6162291 13773 129 182802 182803 1 16 Same + + 0.000000 0 0.000000 0.00000000 1.419928 3.045347 1.0387963 1052 Lactate dehydrogenase and related dehydrogenases CHR 2-hydroxyacid dehydrogenase 1.565059 3.314279 1.0318607 - - - hypothetical protein 0.000000e+00 0 2.106284e-02 -3.576433e-03 9.217251e-03 -1.746198e-01 1.026264e+00 3 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4717083 0.4372640 U 0.4686274 0.6162291 13773 129 182803 182804 1 49 Same + + 0.000000 0 0.000000 0.00000000 1.565059 3.314279 1.0318607 - - - hypothetical protein 1.377660 2.936415 1.0150841 - - - hypothetical protein 0.000000e+00 0 3.511837e-02 -8.380931e-03 -9.625870e-02 -4.788354e-01 1.950985e+00 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4086466 0.4088885 U 0.4686274 0.6162291 13773 129 182804 182805 1 61 Convergent + - 0.000000 0 0.000000 0.00000000 1.377660 2.936415 1.0150841 - - - hypothetical protein 1.601342 3.553170 1.0856328 - - - paREP2b 0.000000e+00 0 5.003381e-02 -1.105622e-02 -6.524041e-02 -5.233351e-01 2.162231e+00 0 0 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4021145 0.4066005 U 0.4686274 0.6162291 13773 129 182805 182806 1 52 Same - - 0.000000 0 0.000000 0.00000000 1.601342 3.553170 1.0856328 - - - paREP2b 1.491157 3.216056 1.1141749 - - - paREP2b 0.000000e+00 0 1.214081e-02 5.962604e-03 3.736912e-02 3.876802e-01 1.755887e-01 0 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6291125 0.5861247 U 0.4686274 0.6162291 13773 129 182806 182807 1 83 Divergent - + 0.000000 0 0.000000 0.00000000 1.491157 3.216056 1.1141749 - - - paREP2b 1.493726 3.062904 1.0194836 - - - paREP2a 0.000000e+00 0 6.600226e-06 1.683341e-03 4.095541e-02 2.067170e-01 2.126270e-04 0 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5521176 0.6544230 U 0.4686274 0.6162291 13773 129 182807 182808 1 -16 Same + + 0.000000 0 0.000000 0.00000000 1.493726 3.062904 1.0194836 - - - paREP2a 1.484045 3.207988 1.0702653 98 Ribosomal protein S5 J ribosomal protein S5 0.000000e+00 0 9.372800e-05 1.382258e-03 3.505587e-02 1.850880e-01 3.769564e-03 0 12 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5440228 0.6475210 U 0.4686274 0.6162291 13773 129 182808 182809 1 -3 Same + + 27.817261 0 40.873960 40.87395955 1.484045 3.207988 1.0702653 98 Ribosomal protein S5 J ribosomal protein S5 1.425823 3.177959 1.0860799 1841 Ribosomal protein L30/L7E J ribosomal protein L30 4.432379e-01 12 3.389789e-03 -8.349091e-04 9.928613e-03 -6.610284e-02 3.199235e-01 J 12 12 TRUE TRUE 105 TRUE 2.1902422 2.0205540 0.5480306 2.2661939 0.7776747 1.2514686 0.5021988 0.5350739 Y 1.4497162 0.9331582 13773 129 182809 182810 1 -20 Convergent + - 0.000000 0 0.000000 -0.32267774 1.425823 3.177959 1.0860799 1841 Ribosomal protein L30/L7E J ribosomal protein L30 1.390654 2.992150 1.0346879 1085 Galactose-1-phosphate uridylyltransferase C galactose-1-phosphate uridylyltransferase 6.983762e-03 11 1.236855e-03 1.553097e-03 4.660536e-02 8.218533e-02 1.109406e-01 0 12 11 TRUE TRUE 106 FALSE 0.4469764 0.2510360 0.5480306 0.4469764 0.7764261 0.5700986 0.5177147 0.6027125 N 0.5492530 0.5504758 13773 129 182810 182811 1 -10 Same - - 15.458584 0 42.294002 41.63722285 1.390654 2.992150 1.0346879 1085 Galactose-1-phosphate uridylyltransferase C galactose-1-phosphate uridylyltransferase 1.466104 3.272252 1.1306714 153 Galactokinase G galactokinase 7.598513e-02 11 5.692719e-03 -8.935391e-04 1.470958e-03 -1.139127e-01 5.282155e-01 0 11 21 FALSE TRUE 105 TRUE 2.5645024 2.0281612 0.5480306 2.2231598 0.7764261 0.9382478 0.4872188 0.4879284 N 0.5492530 0.9006378 13773 129 182811 182812 1 -15 Same - - 0.000000 0 0.000000 -0.05715841 1.466104 3.272252 1.1306714 153 Galactokinase G galactokinase 1.413562 3.345486 1.1513305 1994 Zn-dependent proteases R conserved hypothetical protein 3.280771e-03 6 2.760645e-03 -5.565326e-04 1.731541e-02 -6.336284e-02 2.557891e-01 21 6 FALSE TRUE 104 TRUE 0.4469764 0.3074832 0.5480306 0.4469764 0.7537284 0.5207449 0.5028700 0.5602596 U 0.4686274 0.5594987 13773 129 182812 182813 1 134 Same - - 0.000000 0 0.000000 0.00000000 1.413562 3.345486 1.1513305 1994 Zn-dependent proteases R conserved hypothetical protein 1.601691 3.475305 1.1220411 - - - hypothetical protein 0.000000e+00 0 3.539229e-02 -5.685868e-03 7.988441e-03 -2.402685e-01 1.309382e+00 6 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4537766 0.4239342 U 0.4686274 0.6162291 13773 129 182813 182814 1 96 Divergent - + 0.000000 0 0.000000 0.00000000 1.601691 3.475305 1.1220411 - - - hypothetical protein 1.377923 2.979093 1.0568863 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E acylamino-acid-releasing enzyme, conjectural 0.000000e+00 0 5.007199e-02 -1.104237e-02 -1.520309e-01 -5.204708e-01 2.153213e+00 0 6 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4025696 0.4066719 U 0.4686274 0.6162291 13773 129 182814 182815 1 59 Convergent + - 0.000000 0 0.000000 0.00000000 1.377923 2.979093 1.0568863 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E acylamino-acid-releasing enzyme, conjectural 1.486488 3.046647 1.0083925 - - - paREP2b 0.000000e+00 0 1.178646e-02 -2.578461e-03 -1.999040e-02 -2.524053e-01 1.041872e+00 6 0 TRUE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4515071 0.4362530 U 0.4686274 0.6162291 13773 129 182815 182816 1 129 Same - - 0.000000 0 0.000000 0.00000000 1.486488 3.046647 1.0083925 - - - paREP2b 1.451080 3.032765 1.1478676 - - - hypothetical protein 0.000000e+00 0 1.253779e-03 -1.099627e-05 1.748148e-02 3.905504e-02 1.073908e-01 0 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181603 0.6039545 U 0.4686274 0.6162291 13773 129 182816 182817 1 16 Same - - 0.000000 0 0.000000 0.00000000 1.451080 3.032765 1.1478676 - - - hypothetical protein 1.384275 3.002852 1.0065992 - - - hypothetical protein 0.000000e+00 0 4.462800e-03 2.102960e-05 3.242321e-02 -5.145573e-02 4.185683e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5064909 0.5090246 U 0.4686274 0.6162291 13773 129 182817 182818 1 -14 Divergent - + 0.000000 0 0.000000 0.00000000 1.384275 3.002852 1.0065992 - - - hypothetical protein 1.582620 3.488935 1.1201260 - - - hypothetical protein 0.000000e+00 0 3.934049e-02 -8.807620e-03 -4.995177e-02 -4.618258e-01 1.925343e+00 0 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4102004 0.4093718 U 0.4686274 0.6162291 13773 129 182818 182819 1 244 Convergent + - 0.000000 0 0.000000 0.00000000 1.582620 3.488935 1.1201260 - - - hypothetical protein 1.499079 3.707818 1.1788590 - - - hypothetical protein 0.000000e+00 0 6.979014e-03 6.257730e-03 5.594806e-02 4.183297e-01 1.099205e-01 0 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6428337 0.6030494 U 0.4686274 0.6162291 13773 129 182819 182820 1 123 Same - - 0.000000 0 0.000000 0.00000000 1.499079 3.707818 1.1788590 - - - hypothetical protein 1.501093 3.327202 0.9703552 1131 ABC-type multidrug transport system, ATPase component V ABC transporter ATP-binding protein, putative 0.000000e+00 0 4.054951e-06 2.370014e-03 4.894657e-02 2.577004e-01 1.325237e-04 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5727043 0.6548417 U 0.4686274 0.6162291 13773 129 182820 182821 1 277 Same - - 0.000000 0 0.000000 0.00000000 1.501093 3.327202 0.9703552 1131 ABC-type multidrug transport system, ATPase component V ABC transporter ATP-binding protein, putative 1.686433 3.946479 1.1374778 - - - hypothetical protein 0.000000e+00 0 3.435095e-02 1.168151e-02 2.913406e-01 4.945168e-01 2.022583e-01 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6710886 0.5792906 U 0.4686274 0.6162291 13773 129 182821 182822 1 152 Divergent - + 0.000000 0 0.000000 0.00000000 1.686433 3.946479 1.1374778 - - - hypothetical protein 1.452005 2.922482 0.9963554 - - - paREP2a 0.000000e+00 0 5.495629e-02 1.439755e-04 -1.178702e-01 9.831200e-02 7.414756e-01 0 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184167 0.4605849 U 0.4686274 0.6162291 13773 129 182822 182823 1 108 Same + + 0.000000 0 0.000000 0.00000000 1.452005 2.922482 0.9963554 - - - paREP2a 1.459606 3.141127 1.0533924 421 Spermidine synthase E spermidine synthase 0.000000e+00 0 5.776959e-05 5.031047e-06 2.096687e-02 1.833068e-02 6.008332e-03 0 20 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177706 0.6454790 U 0.4686274 0.6162291 13773 129 182823 182824 1 -7 Same + + 0.000000 0 0.000000 -3.52911976 1.459606 3.141127 1.0533924 421 Spermidine synthase E spermidine synthase 1.406568 3.152744 1.1108221 452 Phosphopantothenoylcysteine synthetase/decarboxylase H pantothenate metabolism flavoprotein (dfp) 3.533918e-02 20 2.813014e-03 -3.681535e-04 2.136434e-02 -6.202111e-02 2.755646e-01 0 20 53 TRUE TRUE 100 TRUE 0.4469764 0.1869980 0.5480306 0.4469764 0.7777535 0.7743315 0.5032581 0.5521597 N 0.5492530 0.5302134 13773 129 182824 182825 1 -44 Convergent + - 0.000000 0 0.000000 0.00000000 1.406568 3.152744 1.1108221 452 Phosphopantothenoylcysteine synthetase/decarboxylase H pantothenate metabolism flavoprotein (dfp) 1.403235 3.185696 1.0495781 2522 Predicted transcriptional regulator R hypothetical protein 0.000000e+00 0 1.110871e-05 2.158650e-03 4.676425e-02 1.325237e-01 1.472486e-03 53 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5250308 0.6510547 U 0.4686274 0.6162291 13773 129 182825 182826 1 420 Divergent - + 0.000000 0 0.000000 0.00000000 1.403235 3.185696 1.0495781 2522 Predicted transcriptional regulator R hypothetical protein 1.357923 2.861993 1.0017964 - - - hypothetical protein 0.000000e+00 0 2.053184e-03 4.501281e-03 8.966505e-02 2.809503e-01 1.214012e-01 0 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5847398 0.6004968 U 0.4686274 0.6162291 13773 129 182826 182827 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.357923 2.861993 1.0017964 - - - hypothetical protein 1.390064 2.960891 1.0337706 1640 4-alpha-glucanotransferase G 4-alpha-glucanotransferase (malQ) 0.000000e+00 0 1.033037e-03 5.732389e-03 7.512741e-02 3.680449e-01 5.265669e-02 0 14 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6189808 0.6230318 U 0.4686274 0.6162291 13773 129 182827 182828 1 127 Convergent + - 0.000000 0 0.000000 0.00000000 1.390064 2.960891 1.0337706 1640 4-alpha-glucanotransferase G 4-alpha-glucanotransferase (malQ) 1.337847 2.824243 0.9652678 - - - paREP2a 0.000000e+00 0 2.726652e-03 6.963655e-03 1.253482e-01 4.247563e-01 1.171604e-01 14 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6456766 0.6014840 U 0.4686274 0.6162291 13773 129 182828 182829 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.337847 2.824243 0.9652678 - - - paREP2a 1.430078 2.895921 0.9853456 - - - paREP2a 0.000000e+00 0 8.506528e-03 2.420276e-03 1.744883e-02 9.694818e-02 5.332474e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182720 0.4866369 U 0.4686274 0.6162291 13773 129 182829 182830 1 158 Divergent - + 0.000000 0 0.000000 0.00000000 1.430078 2.895921 0.9853456 - - - paREP2a 1.452624 3.138590 1.0325003 - - - paREP2b 0.000000e+00 0 5.083390e-04 -2.623983e-05 1.928092e-02 -1.276793e-02 5.108363e-02 0 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175012 0.6235106 U 0.4686274 0.6162291 13773 129 182830 182831 1 44 Same + + 0.000000 0 0.000000 0.00000000 1.452624 3.138590 1.0325003 - - - paREP2b 1.475963 3.167777 1.0968401 - - - paREP2b 0.000000e+00 0 5.446925e-04 3.024601e-05 2.262051e-02 3.655299e-02 4.717197e-02 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177838 0.6250684 U 0.4686274 0.6162291 13773 129 182831 182832 1 33 Convergent + - 0.000000 0 0.000000 0.00000000 1.475963 3.167777 1.0968401 - - - paREP2b 1.580579 3.370731 1.1207539 164 Ribonuclease HII L ribonuclease HII (rnhB) 0.000000e+00 0 1.094456e-02 3.174057e-03 9.869853e-02 2.720047e-01 2.496164e-01 0 24 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5811452 0.5628925 U 0.4686274 0.6162291 13773 129 182832 182833 1 196 Same - - 0.000000 0 0.000000 -0.05715841 1.580579 3.370731 1.1207539 164 Ribonuclease HII L ribonuclease HII (rnhB) 1.343516 3.027064 1.0518192 1695 Predicted transcriptional regulators K conserved hypothetical protein 1.541017e-02 1 5.619894e-02 -1.393622e-02 -1.550369e-01 -6.761986e-01 2.704927e+00 0 24 1 FALSE TRUE 101 TRUE 0.4469764 0.3074832 0.5480306 0.4469764 0.6329203 0.6399605 0.3891275 0.4024166 N 0.5492530 0.5682007 13773 129 182833 182834 1 -7 Same - - 0.000000 0 0.000000 -0.05715841 1.343516 3.027064 1.0518192 1695 Predicted transcriptional regulators K conserved hypothetical protein 1.475173 3.261157 1.1012299 171 NAD synthase H NH(3)-dependent NAD(+) synthetase 1.793207e-02 1 1.733367e-02 -2.565339e-03 -3.737441e-02 -2.607031e-01 1.290133e+00 0 1 20 FALSE TRUE 100 TRUE 0.4469764 0.3074832 0.5480306 0.4469764 0.6329203 0.6618908 0.4498531 0.4244553 N 0.5492530 0.5682007 13773 129 182834 182835 1 20 Same - - 0.000000 0 0.000000 -1.76552940 1.475173 3.261157 1.1012299 171 NAD synthase H NH(3)-dependent NAD(+) synthetase 1.338908 2.943581 1.0263930 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acetyltransferase 6.100492e-03 20 1.856827e-02 -2.674919e-03 2.015793e-02 -2.678087e-01 1.341188e+00 0 20 40 FALSE TRUE 99 TRUE 0.4469764 0.1990928 0.5480306 0.4469764 0.7777535 0.5576421 0.4476607 0.4226076 N 0.5492530 0.5340501 13773 129 182835 182836 1 44 Same - - 0.000000 0 0.000000 -0.21333955 1.338908 2.943581 1.0263930 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acetyltransferase 1.384633 3.028202 1.0584629 3839 ABC-type sugar transport systems, ATPase components G ABC transporter ATP-binding protein, putative 7.675236e-03 6 2.090774e-03 7.509545e-03 8.772758e-02 4.615837e-01 8.326967e-02 0 40 6 FALSE TRUE 98 TRUE 0.4469764 0.2707622 0.5480306 0.4469764 0.7537284 0.5752379 0.6604111 0.6130924 N 0.5492530 0.5566869 13773 129 182836 182837 1 57 Divergent - + 0.000000 0 0.000000 0.00000000 1.384633 3.028202 1.0584629 3839 ABC-type sugar transport systems, ATPase components G ABC transporter ATP-binding protein, putative 1.414242 3.107038 1.0880720 - - - hypothetical protein 0.000000e+00 0 8.767104e-04 2.480208e-03 4.192358e-02 1.473858e-01 7.976398e-02 6 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5300028 0.6145887 U 0.4686274 0.6162291 13773 129 182837 182838 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.414242 3.107038 1.0880720 - - - hypothetical protein 1.484955 3.264946 1.0781863 500 SAM-dependent methyltransferases QR conserved hypothetical protein 0.000000e+00 0 5.000297e-03 -1.246854e-03 5.514600e-03 -1.095630e-01 4.581929e-01 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4882674 0.5025415 U 0.4686274 0.6162291 13773 129 182838 182839 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.484955 3.264946 1.0781863 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.427781 3.156202 1.0978912 1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes I DNA endonuclease, conjectural 0.000000e+00 0 3.268833e-03 -7.924579e-04 1.002739e-02 -5.744993e-02 3.019515e-01 0 1 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5047650 0.5408188 U 0.4686274 0.6162291 13773 129 182839 182840 1 16 Same + + 0.000000 0 0.000000 0.00000000 1.427781 3.156202 1.0978912 1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes I DNA endonuclease, conjectural 1.390972 3.188911 1.1032540 1846 Transcriptional regulators K conserved hypothetical protein 0.000000e+00 0 1.354930e-03 1.426661e-03 4.527384e-02 6.962974e-02 1.262621e-01 0 1 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181001 0.5992342 N 0.5492530 0.6245624 13773 129 182840 182841 1 393 Convergent + - 0.000000 0 0.000000 0.00000000 1.390972 3.188911 1.1032540 1846 Transcriptional regulators K conserved hypothetical protein 1.493025 3.245094 1.1139339 274 Deoxyribose-phosphate aldolase F deoxyribose-phosphate aldolase 0.000000e+00 0 1.041494e-02 -2.515480e-03 -1.354346e-02 -2.267723e-01 9.085616e-01 0 0 40 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4580089 0.4456325 N 0.5492530 0.6245624 13773 129 182841 182842 1 56 Divergent - + 0.000000 0 0.000000 -1.39475454 1.493025 3.245094 1.1139339 274 Deoxyribose-phosphate aldolase F deoxyribose-phosphate aldolase 1.481928 2.974131 1.0259355 1254 Acylphosphatases C acylphosphatase, putative 1.223137e-03 20 1.231515e-04 1.271244e-03 3.356762e-02 1.741162e-01 5.889944e-03 0 40 20 FALSE TRUE 100 FALSE 0.4469764 0.2033220 0.5480306 0.4469764 0.7777535 0.4781126 0.5397540 0.6456836 N 0.5492530 0.5353907 13773 129 182842 182843 1 87 Convergent + - 0.000000 0 0.000000 0.00000000 1.481928 2.974131 1.0259355 1254 Acylphosphatases C acylphosphatase, putative 1.402811 2.888818 0.9919772 4353 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 6.259526e-03 -1.483456e-03 7.018717e-03 -1.484077e-01 5.937158e-01 20 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4772818 0.4775886 U 0.4686274 0.6162291 13773 129 182843 182844 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.402811 2.888818 0.9919772 4353 Uncharacterized conserved protein S conserved hypothetical protein 1.396851 3.178993 1.0752143 - - - conserved within P. aerophilum 0.000000e+00 0 3.552245e-05 2.649781e-03 5.328052e-02 1.762342e-01 3.864392e-03 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5407656 0.6474175 U 0.4686274 0.6162291 13773 129 182844 182845 1 51 Same - - 0.000000 0 0.000000 0.00000000 1.396851 3.178993 1.0752143 - - - conserved within P. aerophilum 1.349679 3.598118 1.1970994 - - - hypothetical protein 0.000000e+00 0 2.225133e-03 5.547686e-03 1.043210e-01 3.521215e-01 1.068883e-01 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6136673 0.6041306 U 0.4686274 0.6162291 13773 129 182845 182846 1 49 Divergent - + 0.000000 0 0.000000 0.00000000 1.349679 3.598118 1.1970994 - - - hypothetical protein 1.312713 2.839039 1.0713307 - - - hypothetical protein 0.000000e+00 0 1.366470e-03 1.410557e-02 2.082309e-01 7.114169e-01 1.803795e-02 0 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7581074 0.6386975 U 0.4686274 0.6162291 13773 129 182846 182847 1 150 Same + + 0.000000 0 0.000000 0.00000000 1.312713 2.839039 1.0713307 - - - hypothetical protein 1.398479 3.032677 1.0728404 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 0.000000e+00 0 7.355730e-03 7.338052e-03 6.480681e-02 3.974122e-01 2.286058e-01 0 9 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6329939 0.5712214 U 0.4686274 0.6162291 13773 129 182847 182848 1 1 Convergent + - 0.000000 0 0.000000 -0.05918887 1.398479 3.032677 1.0728404 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 1.353485 2.840380 0.9390975 4911 Uncharacterized conserved protein S conserved hypothetical protein 1.200565e-02 2 2.024427e-03 5.180655e-03 9.854445e-02 3.292844e-01 1.034044e-01 9 2 TRUE TRUE 100 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6838149 0.6157324 0.6034118 0.6048471 U 0.4686274 0.5589164 13773 129 182848 182849 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.353485 2.840380 0.9390975 4911 Uncharacterized conserved protein S conserved hypothetical protein 1.474496 3.085388 0.9937239 - - - hypothetical protein 0.000000e+00 0 1.464346e-02 -2.261928e-03 -2.869737e-02 -2.346224e-01 1.137996e+00 2 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4555234 0.4312543 U 0.4686274 0.6162291 13773 129 182849 182850 1 16 Same - - 0.000000 0 0.000000 0.00000000 1.474496 3.085388 0.9937239 - - - hypothetical protein 1.443715 3.311255 1.1535380 1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J translation initiation factor aIF-2B subunit, conjectural 0.000000e+00 0 9.474208e-04 -1.773707e-04 1.745808e-02 7.138612e-03 8.238618e-02 0 1 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192124 0.6134641 U 0.4686274 0.6162291 13773 129 182850 182851 1 110 Divergent - + 0.000000 0 0.000000 -0.13353139 1.443715 3.311255 1.1535380 1184 Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family J translation initiation factor aIF-2B subunit, conjectural 1.439033 3.191393 1.0813904 1121 ABC-type Mn/Zn transport systems, ATPase component P manganese ABC transporter ATP-binding protein 1.599790e-02 1 2.192484e-05 9.489272e-05 2.208547e-02 -5.477648e-04 2.191648e-03 0 1 23 FALSE TRUE 97 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.6457313 0.5199850 0.6499017 N 0.5492530 0.5604716 13773 129 182851 182852 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.439033 3.191393 1.0813904 1121 ABC-type Mn/Zn transport systems, ATPase component P manganese ABC transporter ATP-binding protein 1.420349 3.611848 1.2522089 1108 ABC-type Mn2+/Zn2+ transport systems, permease components P manganese transport permease protein 0.000000e+00 0 3.491052e-04 3.837030e-04 2.728354e-02 5.167248e-03 3.740350e-02 P 23 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5194599 0.6288792 Y 1.4497162 0.7118045 13773 129 182852 182853 1 279 Same + + 0.000000 0 0.000000 0.00000000 1.420349 3.611848 1.2522089 1108 ABC-type Mn2+/Zn2+ transport systems, permease components P manganese transport permease protein 1.333520 3.039993 1.0566649 1196 Chromosome segregation ATPases D hypothetical protein 0.000000e+00 0 7.539160e-03 3.659264e-03 9.635919e-02 1.870210e-01 4.146055e-01 0 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5447810 0.5098051 N 0.5492530 0.6245624 13773 129 182853 182854 1 170 Same + + 0.000000 0 0.000000 0.00000000 1.333520 3.039993 1.0566649 1196 Chromosome segregation ATPases D hypothetical protein 1.433360 3.095911 1.0620565 535 Predicted Fe-S oxidoreductases R conserved hypothetical protein 0.000000e+00 0 9.968000e-03 2.125561e-03 1.113234e-02 6.278091e-02 6.212295e-01 0 4 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183843 0.4744725 U 0.4686274 0.6162291 13773 129 182854 182855 1 409 Same + + 0.000000 0 0.000000 0.00000000 1.433360 3.095911 1.0620565 535 Predicted Fe-S oxidoreductases R conserved hypothetical protein 1.466817 3.198333 1.0631201 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, degenerate 0.000000e+00 0 1.119361e-03 -2.781392e-04 1.726398e-02 -1.745779e-02 9.756633e-02 4 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5161167 0.6075710 U 0.4686274 0.6162291 13773 129 182855 182856 1 295 Same + + 0.000000 0 0.000000 0.00000000 1.466817 3.198333 1.0631201 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, degenerate 1.459377 3.412024 1.1278763 4904 Uncharacterized protein conserved in archaea S hypothetical protein 0.000000e+00 0 5.535143e-05 1.231511e-04 2.173534e-02 4.171494e-02 4.255485e-03 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183620 0.6470653 U 0.4686274 0.6162291 13773 129 182856 182857 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.459377 3.412024 1.1278763 4904 Uncharacterized protein conserved in archaea S hypothetical protein 1.559105 3.529696 1.0060428 - - - conserved hypothetical protein 0.000000e+00 0 9.945700e-03 8.600082e-04 6.009456e-02 1.346376e-01 3.583442e-01 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5264544 0.5224252 U 0.4686274 0.6162291 13773 129 182857 182858 1 75 Same + + 0.000000 0 0.000000 0.00000000 1.559105 3.529696 1.0060428 - - - conserved hypothetical protein 1.502113 3.201764 1.0095846 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 0.000000e+00 0 3.248171e-03 5.463142e-03 6.168383e-02 4.009473e-01 6.453082e-02 0 13 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6363299 0.6192498 U 0.4686274 0.6162291 13773 129 182858 182859 1 -3 Same + + 4.276666 0 4.276666 4.27666612 1.502113 3.201764 1.0095846 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 1.474926 3.568496 1.1748748 4881 Predicted membrane protein S conserved hypothetical protein 4.882923e-02 2 7.391297e-04 1.193574e-03 2.956680e-02 1.636438e-01 4.136213e-02 13 2 TRUE TRUE 105 TRUE 2.8554574 1.7490992 0.5480306 2.9038657 0.6838149 0.8388236 0.5358104 0.6275054 U 0.4686274 0.8553650 13773 129 182859 182860 1 -7 Same + + 4.276666 0 4.276666 4.27666612 1.474926 3.568496 1.1748748 4881 Predicted membrane protein S conserved hypothetical protein 1.474340 3.094147 1.0730744 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit 1.242508e-01 2 3.432845e-07 5.400028e-04 2.698240e-02 9.683068e-02 7.126832e-05 2 2 TRUE TRUE 106 TRUE 2.8554574 1.7490992 0.5480306 2.9038657 0.6838149 1.0601895 0.5182452 0.6552829 U 0.4686274 0.8553650 13773 129 182860 182861 1 50 Same + + 0.000000 0 0.000000 0.00000000 1.474340 3.094147 1.0730744 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit 1.378926 3.395241 1.1641569 1280 Putative threonine efflux protein E conserved hypothetical protein 3.137307e-03 2 9.103849e-03 -1.662895e-03 1.329369e-02 -1.811747e-01 8.048968e-01 0 2 8 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5183257 0.4698265 0.4547804 N 0.5492530 0.6245624 13773 129 182861 182862 1 69 Convergent + - 0.000000 0 0.000000 -0.14642863 1.378926 3.395241 1.1641569 1280 Putative threonine efflux protein E conserved hypothetical protein 1.401648 3.145457 1.0955937 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein -1.607957e-02 8 5.163226e-04 3.604847e-03 5.583439e-02 2.368859e-01 3.564359e-02 8 15 TRUE TRUE 108 FALSE 0.4469764 0.2777460 0.5480306 0.4469764 0.7652913 0.5247196 0.5636548 0.6297015 U 0.4686274 0.5501407 13773 129 182862 182863 1 243 Divergent - + 0.000000 0 0.000000 -0.53301223 1.401648 3.145457 1.0955937 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.455075 3.257397 1.1345188 1602 Uncharacterized conserved protein S conserved hypothetical protein 7.346311e-02 9 2.854446e-03 -1.831846e-04 1.234623e-02 -5.298358e-02 2.844990e-01 15 9 FALSE TRUE 107 FALSE 0.4469764 0.2331824 0.5480306 0.4469764 0.7702221 0.9331460 0.5059243 0.5488286 U 0.4686274 0.5360523 13773 129 182863 182864 1 6 Convergent + - 0.000000 0 0.000000 -0.13715041 1.455075 3.257397 1.1345188 1602 Uncharacterized conserved protein S conserved hypothetical protein 1.511184 3.444027 1.1142023 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 5.982711e-02 2 3.148197e-03 2.201820e-04 3.235643e-02 7.516982e-02 1.913643e-01 9 2 TRUE TRUE 108 FALSE 0.4469764 0.2786603 0.5480306 0.4469764 0.6838149 0.8821744 0.5178681 0.5826327 U 0.4686274 0.5504290 13773 129 182864 182865 1 316 Same - - 0.000000 0 0.000000 0.00000000 1.511184 3.444027 1.1142023 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 1.483721 3.206512 1.0963511 - - - P. aerophilum family 1964 protein 0.000000e+00 0 7.542289e-04 1.932938e-03 3.691345e-02 2.259465e-01 2.981784e-02 2 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5602307 0.6331508 U 0.4686274 0.6162291 13773 129 182865 182866 1 454 Divergent - + 0.000000 0 0.000000 0.00000000 1.483721 3.206512 1.0963511 - - - P. aerophilum family 1964 protein 1.559834 3.415216 1.1339858 380 Trehalose-6-phosphate synthase G trehalose-6-phosphate synthase 0.000000e+00 0 5.793262e-03 3.505707e-03 8.893689e-02 3.081642e-01 1.443184e-01 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5951373 0.5943153 U 0.4686274 0.6162291 13773 129 182866 182867 1 -9 Convergent + - 0.000000 0 0.000000 0.00000000 1.559834 3.415216 1.1339858 380 Trehalose-6-phosphate synthase G trehalose-6-phosphate synthase 1.554615 3.416736 1.1282744 438 Glycosyltransferase M glycosyl transferase, conjectural 0.000000e+00 0 2.724588e-05 1.119353e-02 1.488099e-01 5.906978e-01 2.597465e-04 0 0 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7164421 0.6541658 N 0.5492530 0.6245624 13773 129 182867 182868 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.554615 3.416736 1.1282744 438 Glycosyltransferase M glycosyl transferase, conjectural 1.708339 3.923443 1.0941710 - - - conserved within P. aerophilum 0.000000e+00 0 2.363110e-02 2.652242e-02 4.714489e-01 7.383722e-01 4.421934e-02 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7648766 0.6262469 U 0.4686274 0.6162291 13773 129 182868 182869 1 331 Divergent - + 0.000000 0 0.000000 0.00000000 1.708339 3.923443 1.0941710 - - - conserved within P. aerophilum 1.590809 3.450597 1.0931708 - - - conserved hypothetical protein 0.000000e+00 0 1.381316e-02 3.582250e-02 3.212834e-01 8.262914e-01 1.433377e-02 0 2 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7903601 0.6407068 U 0.4686274 0.6162291 13773 129 182869 182870 1 -3 Same + + 2.856470 0 5.519058 5.51905803 1.590809 3.450597 1.0931708 - - - conserved hypothetical protein 1.543334 3.287048 1.0703486 438 Glycosyltransferase M trehalose synthase 8.678342e-02 2 2.253880e-03 1.281816e-02 1.427179e-01 6.166159e-01 1.603537e-02 2 4 TRUE TRUE 106 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 0.9642105 0.7255524 0.6397376 U 0.4686274 0.8613043 13773 129 182870 182871 1 897 Same + + 0.000000 0 0.000000 0.00000000 1.543334 3.287048 1.0703486 438 Glycosyltransferase M trehalose synthase 1.493534 3.218844 1.0895765 561 Predicted hydrolases of the HAD superfamily R hypothetical protein 0.000000e+00 0 2.480070e-03 3.874522e-03 4.908248e-02 3.330504e-01 7.010506e-02 4 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6049993 0.6177812 U 0.4686274 0.6162291 13773 129 182871 182872 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.493534 3.218844 1.0895765 561 Predicted hydrolases of the HAD superfamily R hypothetical protein 1.449813 3.230616 1.0966563 247 Fe-S oxidoreductase C conserved hypothetical protein 0.000000e+00 0 1.911502e-03 -6.656435e-05 1.545588e-02 3.775042e-02 1.425743e-01 0 1 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179044 0.5949759 U 0.4686274 0.6162291 13773 129 182872 182873 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.449813 3.230616 1.0966563 247 Fe-S oxidoreductase C conserved hypothetical protein 1.411396 3.019494 0.9870938 247 Fe-S oxidoreductase C glycolate oxidase subunit, putative 1.851224e-04 1 1.475868e-03 6.317686e-05 2.553256e-02 -2.464176e-02 1.460730e-01 C 1 1 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4421536 0.5140658 0.5939828 Y 1.4497162 0.7118045 13773 129 182873 182874 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.411396 3.019494 0.9870938 247 Fe-S oxidoreductase C glycolate oxidase subunit, putative 1.422079 3.138954 1.0967730 247 Fe-S oxidoreductase C glycolate oxidase subunit glcF 4.292035e-03 1 1.141179e-04 1.172460e-03 3.256612e-02 6.125895e-02 9.203038e-03 C 1 20 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5388554 0.5184584 0.6433585 Y 1.4497162 0.7118045 13773 129 182874 182875 1 -3 Same - - 2.856470 0 2.856470 2.85647021 1.422079 3.138954 1.0967730 247 Fe-S oxidoreductase C glycolate oxidase subunit glcF 1.401111 3.106620 1.0161523 277 FAD/FMN-containing dehydrogenases C glycolate oxidase subunit glcE 3.305270e-03 2 4.396421e-04 1.473956e-03 4.220986e-02 8.334978e-02 4.167489e-02 C 20 2 FALSE TRUE 109 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6838149 0.5221400 0.5176893 0.6273196 Y 1.4497162 0.8983990 13773 129 182875 182876 1 -3 Same - - 5.629059 0 5.629059 5.62905893 1.401111 3.106620 1.0161523 277 FAD/FMN-containing dehydrogenases C glycolate oxidase subunit glcE 1.361342 2.931105 1.0323028 277 FAD/FMN-containing dehydrogenases C glycolate oxidase subunit glcD 1.836843e-02 2 1.581559e-03 4.527885e-03 8.785159e-02 2.920376e-01 9.423910e-02 C 2 38 FALSE TRUE 108 TRUE 2.7915509 1.7992260 0.5480306 2.8430153 0.6838149 0.6646445 0.5901232 0.6091015 Y 1.4497162 0.9071815 13773 129 182876 182877 1 57 Divergent - + 0.000000 0 0.000000 -0.05918887 1.361342 2.931105 1.0323028 277 FAD/FMN-containing dehydrogenases C glycolate oxidase subunit glcD 1.356614 2.920369 1.0402020 2225 Malate synthase C malate synthase (glcB) 9.094140e-03 1 2.235989e-05 8.534901e-03 1.227496e-01 5.302787e-01 6.808775e-04 C 38 1 FALSE TRUE 107 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.5875828 0.6885450 0.6526075 Y 1.4497162 0.6609110 13773 129 182877 182878 1 30 Same + + 0.000000 0 0.000000 -0.05918887 1.356614 2.920369 1.0402020 2225 Malate synthase C malate synthase (glcB) 1.431606 3.225571 1.0906848 247 Fe-S oxidoreductase C conserved hypothetical protein 4.118834e-02 1 5.623888e-03 1.875346e-03 2.084640e-02 7.112107e-02 4.165846e-01 C 1 4 TRUE TRUE 108 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.8108260 0.5180499 0.5093800 Y 1.4497162 0.6609110 13773 129 182878 182879 1 -3 Same + + 5.495528 0 10.748383 10.74838253 1.431606 3.225571 1.0906848 247 Fe-S oxidoreductase C conserved hypothetical protein 1.533988 3.230891 1.1061735 1139 Uncharacterized conserved protein containing a ferredoxin-like domain C conserved hypothetical protein 5.812567e-02 4 1.048190e-02 -1.634259e-03 1.795946e-02 -6.655637e-02 6.236514e-01 C 4 10 TRUE TRUE 109 TRUE 2.7996416 1.8534968 0.5480306 2.7445446 0.7323301 0.8774089 0.5019985 0.4741862 Y 1.4497162 0.9127625 13773 129 182879 182880 1 4 Convergent + - 0.000000 0 0.000000 0.00000000 1.533988 3.230891 1.1061735 1139 Uncharacterized conserved protein containing a ferredoxin-like domain C conserved hypothetical protein 1.679688 3.979781 1.1341565 530 Ca2+/Na+ antiporter P conserved within P. aerophilum part 2, authentic frameshift 0.000000e+00 0 2.122858e-02 1.885594e-02 3.562381e-01 6.639663e-01 6.929460e-02 0 10 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7404670 0.6180080 N 0.5492530 0.6245624 13773 129 182880 182881 1 76 Same - - 0.000000 0 0.000000 0.00000000 1.679688 3.979781 1.1341565 530 Ca2+/Na+ antiporter P conserved within P. aerophilum part 2, authentic frameshift 1.629435 4.022992 1.1861902 - - - conserved within P. aerophilum part 1, authentic frameshift 0.000000e+00 0 2.525331e-03 4.064615e-02 4.441283e-01 8.681507e-01 2.488501e-03 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7984338 0.6493745 U 0.4686274 0.6162291 13773 129 182881 182882 1 201 Divergent - + 0.000000 0 0.000000 0.00000000 1.629435 4.022992 1.1861902 - - - conserved within P. aerophilum part 1, authentic frameshift 1.642961 3.834153 1.1587509 - - - conserved hypothetical protein 0.000000e+00 0 1.829471e-04 3.410722e-02 4.322245e-01 8.389106e-01 3.115780e-04 0 1 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7922519 0.6539188 U 0.4686274 0.6162291 13773 129 182882 182883 1 2 Convergent + - 0.000000 0 0.000000 -0.13353139 1.642961 3.834153 1.1587509 - - - conserved hypothetical protein 1.430960 3.076855 1.0554650 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R conserved hypothetical protein 7.158483e-02 1 4.494429e-02 -3.914235e-03 -1.171642e-01 -9.723414e-02 1.060758e+00 1 1 TRUE TRUE 109 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.9205230 0.4929396 0.4353079 U 0.4686274 0.5517368 13773 129 182883 182884 1 27 Same - - 0.000000 0 0.000000 -0.13353139 1.430960 3.076855 1.0554650 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R conserved hypothetical protein 1.399543 3.141057 1.1132168 4608 ABC-type oligopeptide transport system, ATPase component E dipeptide transport ATP-binding protein 8.738481e-03 1 9.870296e-04 1.059423e-03 3.889172e-02 4.478419e-02 1.029115e-01 1 39 FALSE TRUE 108 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.5857888 0.5185372 0.6052131 U 0.4686274 0.5517368 13773 129 182884 182885 1 -3 Same - - 41.985143 0 85.843905 82.21114082 1.399543 3.141057 1.1132168 4608 ABC-type oligopeptide transport system, ATPase component E dipeptide transport ATP-binding protein 1.431131 3.096743 1.0554192 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP dipeptide transport ATP-binding protein 2.472563e-01 39 9.977809e-04 1.050575e-03 2.723672e-02 4.314973e-02 1.053882e-01 39 48 FALSE TRUE 107 TRUE 2.0858754 2.0698338 0.5480306 2.0720159 0.7736367 1.1850303 0.5184263 0.6043969 U 0.4686274 0.9073233 13773 129 182885 182886 1 -3 Same - - 22.160864 0 38.838210 34.27766989 1.431131 3.096743 1.0554192 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP dipeptide transport ATP-binding protein 1.629159 3.790344 1.1728653 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide ABC transporter, permease protein 9.526239e-02 25 3.921530e-02 -3.601900e-03 5.783158e-02 -9.181952e-02 1.015408e+00 48 25 FALSE TRUE 106 TRUE 2.2944843 1.9978612 0.5480306 2.2928225 0.7766777 0.9945586 0.4947389 0.4382819 U 0.4686274 0.8969529 13773 129 182886 182887 1 2 Same - - 15.901920 0 23.012616 20.92360490 1.629159 3.790344 1.1728653 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide ABC transporter, permease protein 1.608239 3.754390 1.0941066 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide ABC transporter, permease protein 3.885395e-02 25 4.376508e-04 2.788206e-02 3.289656e-01 7.971603e-01 7.215181e-04 25 36 FALSE TRUE 105 TRUE 2.5308252 1.9256982 0.5480306 2.5449863 0.7766777 0.7965433 0.7842467 0.6523872 U 0.4686274 0.8851948 13773 129 182887 182888 1 7 Same - - 0.000000 0 0.000000 0.00000000 1.608239 3.754390 1.0941066 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide ABC transporter, permease protein 1.619210 3.519007 1.0644511 747 ABC-type dipeptide transport system, periplasmic component E dipeptide binding protein 0.000000e+00 0 1.203509e-04 2.632149e-02 3.375409e-01 7.850106e-01 1.702194e-04 36 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7795811 0.6547351 U 0.4686274 0.6162291 13773 129 182888 182889 1 91 Same - - 0.000000 0 0.000000 0.00000000 1.619210 3.519007 1.0644511 747 ABC-type dipeptide transport system, periplasmic component E dipeptide binding protein 1.398456 2.965563 1.0571576 4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system S tricorn protease 0.000000e+00 0 4.873212e-02 -8.883657e-03 -1.475351e-01 -3.890803e-01 1.764840e+00 0 6 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4216377 0.4111186 U 0.4686274 0.6162291 13773 129 182889 182890 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.398456 2.965563 1.0571576 4946 Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system S tricorn protease 1.376435 3.368019 1.1511502 4243 Predicted membrane protein S hypothetical protein 0.000000e+00 0 4.849558e-04 3.968038e-03 7.428555e-02 2.693118e-01 3.308323e-02 6 0 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5786696 0.6310514 U 0.4686274 0.6162291 13773 129 182890 182891 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.376435 3.368019 1.1511502 4243 Predicted membrane protein S hypothetical protein 1.442563 3.131736 1.0590987 3427 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.372918e-03 6.619024e-04 1.440599e-02 -8.534529e-03 3.989430e-01 0 5 TRUE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191052 0.5128399 U 0.4686274 0.6162291 13773 129 182891 182892 1 107 Same - - 0.000000 0 0.000000 -0.07232066 1.442563 3.131736 1.0590987 3427 Uncharacterized conserved protein S conserved hypothetical protein 1.398103 3.182914 1.1020869 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 3.777386e-02 1 1.976667e-03 4.705653e-04 3.325342e-02 -6.064286e-03 2.050290e-01 5 1 FALSE TRUE 102 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.7874252 0.5195057 0.5780796 U 0.4686274 0.5573725 13773 129 182892 182893 1 50 Same - - 0.000000 0 0.000000 0.00000000 1.398103 3.182914 1.1020869 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.486751 3.148604 1.0675211 - - - hypothetical protein 0.000000e+00 0 7.858494e-03 -1.884236e-03 -5.330191e-03 -1.856345e-01 7.427979e-01 1 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4685976 0.4602020 U 0.4686274 0.6162291 13773 129 182893 182894 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.486751 3.148604 1.0675211 - - - hypothetical protein 1.411740 3.162937 1.0927483 2379 Putative glycerate kinase G conserved hypothetical protein 0.000000e+00 0 5.626631e-03 -1.402047e-03 5.162643e-03 -1.259199e-01 5.193287e-01 0 17 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4830705 0.4896794 U 0.4686274 0.6162291 13773 129 182894 182895 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.411740 3.162937 1.0927483 2379 Putative glycerate kinase G conserved hypothetical protein 1.472392 3.198898 1.0176870 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 3.678673e-03 -8.326812e-04 8.128634e-03 -8.524163e-02 3.410990e-01 17 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4966322 0.5274616 U 0.4686274 0.6162291 13773 129 182895 182896 1 -27 Same + + 0.000000 0 0.000000 0.00000000 1.472392 3.198898 1.0176870 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.386444 2.940861 1.0805537 1708 Predicted nucleotidyltransferases R conserved within P. aerophilum part 1, authentic frameshift 0.000000e+00 0 7.387100e-03 -1.363884e-03 1.438348e-02 -1.533470e-01 6.756007e-01 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4758837 0.4673400 U 0.4686274 0.6162291 13773 129 182896 182897 1 9 Same + + 0.000000 0 0.000000 0.00000000 1.386444 2.940861 1.0805537 1708 Predicted nucleotidyltransferases R conserved within P. aerophilum part 1, authentic frameshift 1.348857 2.938817 1.1404714 1708 Predicted nucleotidyltransferases R conserved within P. aerophilum part 2, authentic frameshift 0.000000e+00 0 1.412802e-03 6.659610e-03 1.145907e-01 4.205738e-01 6.221253e-02 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6444089 0.6197187 U 0.4686274 0.6162291 13773 129 182897 182898 1 42 Same + + 0.000000 0 0.000000 0.00000000 1.348857 2.938817 1.1404714 1708 Predicted nucleotidyltransferases R conserved within P. aerophilum part 2, authentic frameshift 1.484954 3.265165 1.0856873 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 1.852246e-02 -3.441225e-03 -4.333725e-02 -3.205520e-01 1.424203e+00 0 1 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4351308 0.4192722 U 0.4686274 0.6162291 13773 129 182898 182899 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.484954 3.265165 1.0856873 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.415386 3.650212 1.1290516 - - - conserved hypothetical protein 0.000000e+00 0 4.839762e-03 -1.208444e-03 7.040392e-03 -1.055973e-01 4.447856e-01 1 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4894252 0.5049034 U 0.4686274 0.6162291 13773 129 182899 182900 1 -11 Convergent + - 0.000000 0 0.000000 0.00000000 1.415386 3.650212 1.1290516 - - - conserved hypothetical protein 1.509167 3.836491 1.1630198 - - - hypothetical protein 0.000000e+00 0 8.794883e-03 -2.080277e-03 1.598354e-03 -1.452955e-01 6.730798e-01 0 0 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4786624 0.4678741 U 0.4686274 0.6162291 13773 129 182900 182901 1 255 Divergent - + 0.000000 0 0.000000 0.00000000 1.509167 3.836491 1.1630198 - - - hypothetical protein 1.600329 3.510829 1.1083420 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein, authentic frameshift 0.000000e+00 0 8.310673e-03 8.604623e-03 1.692007e-01 4.858992e-01 9.189785e-02 0 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6682905 0.6102320 U 0.4686274 0.6162291 13773 129 182901 182902 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.600329 3.510829 1.1083420 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein, authentic frameshift 1.438339 2.906134 1.0157369 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 2.624106e-02 -1.944266e-03 -5.789413e-02 -2.854326e-02 8.062744e-01 0 2 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5126004 0.4545258 U 0.4686274 0.6162291 13773 129 182902 182903 1 33 Convergent + - 0.000000 0 0.000000 -0.13150953 1.438339 2.906134 1.0157369 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.456405 3.180730 1.0716579 3839 ABC-type sugar transport systems, ATPase components G multiple sugar-binding transport ATP-binding 1.190151e-02 2 3.264017e-04 -6.543182e-05 1.960367e-02 -4.786758e-03 3.170203e-02 2 48 TRUE TRUE 105 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.6132969 0.5196908 0.6317872 U 0.4686274 0.5537552 13773 129 182903 182904 1 -3 Same - - 6.915723 0 6.915723 2.64431804 1.456405 3.180730 1.0716579 3839 ABC-type sugar transport systems, ATPase components G multiple sugar-binding transport ATP-binding 1.526762 3.676200 1.1594203 395 ABC-type sugar transport system, permease component G multiple sugar transport permease 1.905451e-01 25 4.950037e-03 3.777689e-04 3.951643e-02 9.573515e-02 2.651894e-01 G 48 25 FALSE TRUE 104 TRUE 2.7566619 1.7000583 0.5480306 2.8254320 0.7766777 1.1322281 0.5180563 0.5552137 Y 1.4497162 0.8963834 13773 129 182904 182905 1 -3 Same - - 19.372710 0 22.263082 20.55980194 1.526762 3.676200 1.1594203 395 ABC-type sugar transport system, permease component G multiple sugar transport permease 1.598461 3.594768 1.1379881 1175 ABC-type sugar transport systems, permease components G multiple sugar transport permease 1.207017e-01 25 5.140868e-03 1.108438e-02 1.908413e-01 5.693456e-01 4.105055e-02 G 25 26 FALSE TRUE 103 TRUE 2.3934852 1.9215157 0.5480306 2.5507294 0.7766777 1.0543956 0.7075462 0.6277229 Y 1.4497162 0.9230737 13773 129 182905 182906 1 -3 Same - - 6.769770 0 6.769770 6.51845511 1.598461 3.594768 1.1379881 1175 ABC-type sugar transport systems, permease components G multiple sugar transport permease 1.536019 3.368125 1.0768305 1653 ABC-type sugar transport system, periplasmic component G multiple sugar binding protein 5.944019e-02 4 3.899099e-03 1.244581e-02 1.295168e-01 6.024470e-01 2.697359e-02 G 26 4 FALSE TRUE 102 TRUE 2.7639651 1.8071882 0.5480306 2.8314523 0.7323301 0.8805827 0.7205571 0.6345527 Y 1.4497162 0.9083174 13773 129 182906 182907 1 -24 Same - - 0.000000 0 0.000000 0.00000000 1.536019 3.368125 1.0768305 1653 ABC-type sugar transport system, periplasmic component G multiple sugar binding protein 1.523049 3.656721 1.1222440 - - - hypothetical protein 0.000000e+00 0 1.682044e-04 6.063991e-03 8.649229e-02 4.459394e-01 3.583442e-03 4 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6537535 0.6476453 U 0.4686274 0.6162291 13773 129 182907 182908 1 428 Divergent - + 0.000000 0 0.000000 0.00000000 1.523049 3.656721 1.1222440 - - - hypothetical protein 1.983408 4.378442 1.1172547 - - - hypothetical protein 0.000000e+00 0 2.119303e-01 3.812235e-02 1.172219e+00 6.375464e-01 1.295558e-01 0 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7323078 0.5982270 U 0.4686274 0.6162291 13773 129 182908 182909 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.983408 4.378442 1.1172547 - - - hypothetical protein 1.426052 3.197203 1.1057617 1573 Uracil-DNA glycosylase L uracil-DNA glycosylase (Pa-UDGb) 0.000000e+00 0 3.106458e-01 -1.348165e-02 -8.540464e-01 -1.632180e-01 1.350091e+00 0 11 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4739474 0.4223570 U 0.4686274 0.6162291 13773 129 182909 182910 1 -3 Same + + 0.000000 0 0.000000 -0.43963558 1.426052 3.197203 1.1057617 1573 Uracil-DNA glycosylase L uracil-DNA glycosylase (Pa-UDGb) 1.364975 3.490128 1.1842578 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.896396e-02 11 3.730456e-03 2.189899e-03 6.367716e-02 1.139139e-01 2.844990e-01 11 18 TRUE TRUE 102 TRUE 0.4469764 0.2375349 0.5480306 0.4469764 0.7764261 0.6702039 0.5207369 0.5488286 U 0.4686274 0.5374312 13773 129 182910 182911 1 14 Same + + 0.000000 0 0.000000 -0.53435612 1.364975 3.490128 1.1842578 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.427123 3.102506 1.0658297 2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism Q conserved hypothetical protein 2.110696e-02 5 3.862456e-03 2.097328e-03 2.779072e-02 1.048222e-01 2.985872e-01 18 5 TRUE TRUE 103 TRUE 0.4469764 0.2327403 0.5480306 0.4469764 0.7448207 0.6849861 0.5192886 0.5425599 U 0.4686274 0.5359122 13773 129 182911 182912 1 51 Same + + 0.000000 0 0.000000 -0.13150953 1.427123 3.102506 1.0658297 2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism Q conserved hypothetical protein 1.303558 2.828731 0.9815809 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) 2.262946e-03 5 1.526830e-02 3.587872e-03 1.166934e-01 1.409558e-01 6.188122e-01 0 5 21 TRUE TRUE 104 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.7448207 0.4996640 0.5281566 0.4748312 N 0.5492530 0.5624819 13773 129 182912 182913 1 11 Convergent + - 0.000000 0 0.000000 0.00000000 1.303558 2.828731 0.9815809 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) 1.591944 3.354662 1.0058994 247 Fe-S oxidoreductase C conserved iron-sulfur protein 2.884300e-03 2 8.316627e-02 -2.077831e-02 -2.275421e-01 -7.989892e-01 3.203084e+00 0 21 2 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5119009 0.3834394 0.4005012 N 0.5492530 0.6245624 13773 129 182913 182914 1 341 Same - - 0.000000 0 0.000000 0.00000000 1.591944 3.354662 1.0058994 247 Fe-S oxidoreductase C conserved iron-sulfur protein 1.455056 3.227308 1.0982611 2847 Uncharacterized protein conserved in bacteria S conserved hypothetical protein 0.000000e+00 0 1.873837e-02 5.148354e-04 -2.337569e-02 1.112434e-01 5.215434e-01 2 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5201276 0.4890700 U 0.4686274 0.6162291 13773 129 182914 182915 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.455056 3.227308 1.0982611 2847 Uncharacterized protein conserved in bacteria S conserved hypothetical protein 1.385291 3.394437 1.1477610 109 Polyprenyltransferase (cytochrome oxidase assembly factor) O cytochrome C oxidase assembly factor 0.000000e+00 0 4.867158e-03 -2.421302e-04 2.896890e-02 -7.159227e-02 4.613151e-01 0 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5009347 0.5017230 U 0.4686274 0.6162291 13773 129 182915 182916 1 36 Same - - 0.000000 0 0.000000 0.00000000 1.385291 3.394437 1.1477610 109 Polyprenyltransferase (cytochrome oxidase assembly factor) O cytochrome C oxidase assembly factor 1.452395 3.695954 1.2043972 - - - possible respiratory chain protein 0.000000e+00 0 4.502909e-03 -6.621277e-05 8.869725e-03 -5.853721e-02 4.295630e-01 0 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5042454 0.5075206 U 0.4686274 0.6162291 13773 129 182916 182917 1 -40 Same - - 0.000000 0 0.000000 0.00000000 1.452395 3.695954 1.2043972 - - - possible respiratory chain protein 1.508304 3.492688 1.1595154 - - - possible respiratory chain protein 0.000000e+00 0 3.125891e-03 5.700667e-05 2.962690e-02 5.943778e-02 2.029492e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185825 0.5787234 U 0.4686274 0.6162291 13773 129 182917 182918 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.508304 3.492688 1.1595154 - - - possible respiratory chain protein 1.361189 3.163014 1.1108114 843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 C cytochrome C oxidase subunit I /III 0.000000e+00 0 2.164293e-02 -5.133632e-03 -2.684801e-02 -3.989601e-01 1.621078e+00 0 4 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4197390 0.4141928 U 0.4686274 0.6162291 13773 129 182918 182919 1 0 Same - - 2.856470 0 2.856470 2.85647021 1.361189 3.163014 1.1108114 843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 C cytochrome C oxidase subunit I /III 1.441651 3.071612 1.0249051 1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 C cytochrome C oxidase subunit II 4.118834e-02 1 6.474143e-03 8.787630e-04 1.059006e-02 -3.297191e-03 5.193287e-01 C 4 1 FALSE TRUE 99 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6329203 0.8108260 0.5198349 0.4896794 Y 1.4497162 0.8983990 13773 129 182919 182920 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.441651 3.071612 1.0249051 1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 C cytochrome C oxidase subunit II 1.393567 3.213829 1.0912597 - - - respiratory chain protein (soxI homolog) 0.000000e+00 0 2.312093e-03 5.633397e-04 3.557518e-02 -2.162787e-03 2.249511e-01 1 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199294 0.5726631 U 0.4686274 0.6162291 13773 129 182920 182921 1 172 Divergent - + 0.000000 0 0.000000 0.00000000 1.393567 3.213829 1.0912597 - - - respiratory chain protein (soxI homolog) 1.432538 3.531128 1.1582748 - - - possible respiratory chain protein 0.000000e+00 0 1.518789e-03 1.090285e-03 2.589661e-02 3.820924e-02 1.508038e-01 0 1 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180429 0.5929737 U 0.4686274 0.6162291 13773 129 182921 182922 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.432538 3.531128 1.1582748 - - - possible respiratory chain protein 1.412896 3.361749 1.1813085 - - - hypothetical protein 0.000000e+00 0 3.858217e-04 7.258404e-04 3.208522e-02 2.341253e-02 4.262022e-02 1 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174254 0.6270113 U 0.4686274 0.6162291 13773 129 182922 182923 1 105 Same + + 0.000000 0 0.000000 0.00000000 1.412896 3.361749 1.1813085 - - - hypothetical protein 1.432216 3.347600 1.1294959 - - - conserved within P. aerophilum 0.000000e+00 0 3.732511e-04 7.382610e-04 2.654001e-02 2.517951e-02 4.012289e-02 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173926 0.6279101 U 0.4686274 0.6162291 13773 129 182923 182924 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.432216 3.347600 1.1294959 - - - conserved within P. aerophilum 1.375360 2.952954 1.0134064 723 Rieske Fe-S protein C Rieske iron sulfur protein (parR) 0.000000e+00 0 3.232554e-03 1.458092e-03 5.153301e-02 5.499205e-02 2.927449e-01 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187446 0.5451177 U 0.4686274 0.6162291 13773 129 182924 182925 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.375360 2.952954 1.0134064 723 Rieske Fe-S protein C Rieske iron sulfur protein (parR) 1.335048 3.132888 1.0867688 1290 Cytochrome b subunit of the bc complex C cytochrome b/b6 0.000000e+00 0 1.625066e-03 8.846014e-03 1.438620e-01 5.378609e-01 5.160533e-02 C 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6904307 0.6233610 Y 1.4497162 0.7118045 13773 129 182925 182926 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.335048 3.132888 1.0867688 1290 Cytochrome b subunit of the bc complex C cytochrome b/b6 1.386462 3.231335 1.1013340 - - - hypothetical protein 0.000000e+00 0 2.643442e-03 7.554318e-03 8.539627e-02 4.577399e-01 1.029115e-01 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6594011 0.6052131 U 0.4686274 0.6162291 13773 129 182926 182927 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.386462 3.231335 1.1013340 - - - hypothetical protein 1.350646 3.208476 1.1066600 - - - hypothetical protein 0.000000e+00 0 1.282799e-03 6.541518e-03 1.122922e-01 4.134028e-01 5.660236e-02 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6406458 0.6215881 U 0.4686274 0.6162291 13773 129 182927 182928 1 311 Same + + 0.000000 0 0.000000 0.00000000 1.350646 3.208476 1.1066600 - - - hypothetical protein 1.428910 2.997891 1.0396511 1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 C cytochrome C oxidase subunit II 0.000000e+00 0 6.125227e-03 2.265062e-03 2.272939e-02 9.905060e-02 4.155945e-01 0 5 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185461 0.5095219 U 0.4686274 0.6162291 13773 129 182928 182929 1 46 Same + + 0.000000 0 0.000000 -0.13353139 1.428910 2.997891 1.0396511 1622 Heme/copper-type cytochrome/quinol oxidases, subunit 2 C cytochrome C oxidase subunit II 1.367730 3.235138 1.1409101 843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 C cytochrome C oxidase subunit I 3.777386e-02 1 3.742969e-03 1.880966e-03 5.922192e-02 8.705043e-02 3.036408e-01 C 5 1 TRUE TRUE 105 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7874252 0.5176988 0.5402395 Y 1.4497162 0.6543650 13773 129 182929 182930 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.367730 3.235138 1.1409101 843 Heme/copper-type cytochrome/quinol oxidases, subunit 1 C cytochrome C oxidase subunit I 1.413556 3.175243 1.0861823 1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic sys R senC homolog 7.562104e-04 1 2.099959e-03 3.165563e-03 4.361095e-02 1.892174e-01 1.604916e-01 1 4 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5458543 0.5898600 U 0.4686274 0.6162291 13773 129 182930 182931 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.413556 3.175243 1.0861823 1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic sys R senC homolog 1.409303 3.363871 1.1611669 - - - hypothetical protein 0.000000e+00 0 1.808343e-05 1.592560e-03 4.022150e-02 8.872906e-02 1.592641e-03 4 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177624 0.6508783 U 0.4686274 0.6162291 13773 129 182931 182932 1 70 Same + + 0.000000 0 0.000000 0.00000000 1.409303 3.363871 1.1611669 - - - hypothetical protein 1.337693 2.888852 1.0060334 - - - hypothetical protein 0.000000e+00 0 5.127968e-03 4.785584e-03 1.050230e-01 2.693648e-01 2.779871e-01 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5790197 0.5515886 U 0.4686274 0.6162291 13773 129 182932 182933 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.337693 2.888852 1.0060334 - - - hypothetical protein 1.467222 3.121196 1.0701447 - - - hypothetical protein 0.000000e+00 0 1.677765e-02 -1.799751e-03 -3.249894e-02 -2.051067e-01 1.184305e+00 0 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4627947 0.4290592 U 0.4686274 0.6162291 13773 129 182933 182934 1 -46 Same + + 0.000000 0 0.000000 0.00000000 1.467222 3.121196 1.0701447 - - - hypothetical protein 1.427155 3.204283 1.1183158 3420 Nitrous oxidase accessory protein P nosD homolog 0.000000e+00 0 1.605319e-03 -3.836544e-04 1.710745e-02 -3.629384e-02 1.537988e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5104222 0.5921731 U 0.4686274 0.6162291 13773 129 182934 182935 1 -15 Same + + 0.000000 0 0.000000 0.00000000 1.427155 3.204283 1.1183158 3420 Nitrous oxidase accessory protein P nosD homolog 1.451652 3.371354 1.1500161 3842 ABC-type spermidine/putrescine transport systems, ATPase components E branched-chain amino acid ABC transporter, ATP-binding protein, putative 0.000000e+00 0 6.000631e-04 -6.271446e-06 1.917269e-02 -1.458645e-02 6.106930e-02 0 0 0 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5170335 0.6200599 N 0.5492530 0.6245624 13773 129 182935 182936 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.451652 3.371354 1.1500161 3842 ABC-type spermidine/putrescine transport systems, ATPase components E branched-chain amino acid ABC transporter, ATP-binding protein, putative 1.413348 3.635179 1.1932787 - - - hypothetical protein 0.000000e+00 0 1.467197e-03 -9.844225e-06 2.429821e-02 -2.737764e-02 1.431545e-01 0 0 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5129317 0.5946095 U 0.4686274 0.6162291 13773 129 182936 182937 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.413348 3.635179 1.1932787 - - - hypothetical protein 1.382711 3.481358 1.1454906 - - - hypothetical protein 0.000000e+00 0 9.386067e-04 2.613022e-03 5.959348e-02 1.582298e-01 7.976398e-02 0 0 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5338917 0.6145887 U 0.4686274 0.6162291 13773 129 182937 182938 1 140 Same + + 0.000000 0 0.000000 0.00000000 1.382711 3.481358 1.1454906 - - - hypothetical protein 1.409383 3.156166 1.0822115 1846 Transcriptional regulators K conserved hypothetical protein 0.000000e+00 0 7.113775e-04 2.885347e-03 4.697647e-02 1.785489e-01 6.069057e-02 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5417888 0.6202452 U 0.4686274 0.6162291 13773 129 182938 182939 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.409383 3.156166 1.0822115 1846 Transcriptional regulators K conserved hypothetical protein 1.518532 3.892045 1.2385101 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein part 1, authentic frameshift 0.000000e+00 0 1.191358e-02 -2.820530e-03 -5.275404e-03 -1.941172e-01 8.637727e-01 0 0 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4659516 0.4489519 U 0.4686274 0.6162291 13773 129 182939 182940 1 -21 Same + + 0.000000 0 0.000000 0.00000000 1.518532 3.892045 1.2385101 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein part 1, authentic frameshift 1.352978 3.289958 1.1136585 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein part 2, authentic frameshift 0.000000e+00 0 2.740819e-02 -6.607500e-03 -4.336976e-02 -4.662574e-01 1.887197e+00 0 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4095356 0.4097465 U 0.4686274 0.6162291 13773 129 182940 182941 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.352978 3.289958 1.1136585 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein part 2, authentic frameshift 1.452016 3.165479 1.0802208 2107 Predicted periplasmic solute-binding protein R conserved hypothetical protein 0.000000e+00 0 9.808645e-03 -6.135801e-05 -4.575256e-03 -7.829385e-02 7.467719e-01 0 16 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4985027 0.4598829 U 0.4686274 0.6162291 13773 129 182941 182942 1 189 Same + + 0.000000 0 0.000000 -0.38282396 1.452016 3.165479 1.0802208 2107 Predicted periplasmic solute-binding protein R conserved hypothetical protein 1.365143 2.959612 1.0604748 1444 Predicted P-loop ATPase fused to an acetyltransferase R conserved hypothetical protein 3.190737e-02 7 7.546900e-03 -5.377316e-05 3.899929e-02 -7.142735e-02 6.358318e-01 16 7 TRUE TRUE 118 TRUE 0.4469764 0.2444483 0.5480306 0.4469764 0.7596462 0.7476592 0.5011009 0.4717106 U 0.4686274 0.5396202 13773 129 182942 182943 1 -60 Convergent + - 0.000000 0 0.000000 0.00000000 1.365143 2.959612 1.0604748 1444 Predicted P-loop ATPase fused to an acetyltransferase R conserved hypothetical protein 1.458813 3.771380 1.2529012 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 0.000000e+00 0 8.773994e-03 -6.399850e-04 -5.496690e-03 -1.140705e-01 7.375158e-01 7 0 TRUE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4871018 0.4611592 U 0.4686274 0.6162291 13773 129 182943 182944 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.458813 3.771380 1.2529012 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.340019 2.837302 0.9883096 1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain J translation initiation factor aIF-2B beta subunit 0.000000e+00 0 1.411210e-02 -8.264148e-04 4.243580e-02 -1.367586e-01 9.938697e-01 0 9 FALSE TRUE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4803958 0.4397299 U 0.4686274 0.6162291 13773 129 182944 182945 1 34 Same - - 0.000000 0 0.000000 -0.38282396 1.340019 2.837302 0.9883096 1601 Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain J translation initiation factor aIF-2B beta subunit 1.414694 3.099063 1.0454646 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 9.393202e-02 5 5.576469e-03 4.087258e-03 4.044661e-02 2.185582e-01 3.251538e-01 9 5 FALSE TRUE 117 TRUE 0.4469764 0.2444483 0.5480306 0.4469764 0.7448207 0.9882295 0.5565966 0.5328194 U 0.4686274 0.5396202 13773 129 182945 182946 1 2 Same - - 9.772194 0 15.025049 15.02504865 1.414694 3.099063 1.0454646 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.465716 3.131943 1.0716464 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 9.932338e-02 5 2.603200e-03 -5.256363e-04 1.169264e-02 -5.942365e-02 2.389957e-01 5 19 FALSE TRUE 116 TRUE 2.6879054 1.8780151 0.5480306 2.6753053 0.7448207 1.0110272 0.5040202 0.5668045 U 0.4686274 0.8767862 13773 129 182946 182947 1 54 Same - - 2.856470 0 5.519058 3.82588142 1.465716 3.131943 1.0716464 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.347525 2.799513 0.9551740 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 6.022921e-02 19 1.396918e-02 -1.487717e-03 3.021964e-02 -1.800085e-01 1.043440e+00 I 19 33 FALSE TRUE 115 TRUE 2.8950318 1.7442434 0.5480306 2.8617306 0.7779521 0.8837695 0.4705026 0.4361345 Y 1.4497162 0.8999629 13773 129 182947 182948 1 105 Divergent - + 0.000000 0 0.000000 -4.84252779 1.347525 2.799513 0.9551740 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 1.429292 3.043048 1.0713997 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ long-chain-fatty-acid--CoA ligase 1.591294e-01 33 6.685893e-03 2.295576e-03 2.142089e-02 9.885211e-02 4.499187e-01 33 38 FALSE TRUE 114 FALSE 0.4469764 0.1830041 0.5480306 0.4469764 0.7751042 1.0956259 0.5185126 0.5038000 U 0.4686274 0.5201208 13773 129 182948 182949 1 23 Same + + 0.000000 0 0.000000 -0.13353139 1.429292 3.043048 1.0713997 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ long-chain-fatty-acid--CoA ligase 1.499708 3.306845 1.1252015 656 Aldo/keto reductases, related to diketogulonate reductase R aldo-keto reductase family protein 9.094140e-03 1 4.958352e-03 -1.067797e-03 1.294030e-02 -6.307070e-02 3.989430e-01 38 1 TRUE TRUE 115 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.5875828 0.5031035 0.5128399 U 0.4686274 0.5517368 13773 129 182949 182950 1 55 Same + + 0.000000 0 0.000000 -0.13353139 1.499708 3.306845 1.1252015 656 Aldo/keto reductases, related to diketogulonate reductase R aldo-keto reductase family protein 1.364370 2.922893 1.0479052 1024 Enoyl-CoA hydratase/carnithine racemase I 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase 3.085292e-02 1 1.831635e-02 -4.204500e-03 -1.511871e-02 -3.550647e-01 1.457366e+00 1 8 TRUE TRUE 116 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7379657 0.4272166 0.4181253 U 0.4686274 0.5517368 13773 129 182950 182951 1 32 Same + + 0.000000 0 0.000000 -0.95176903 1.364370 2.922893 1.0479052 1024 Enoyl-CoA hydratase/carnithine racemase I 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase 1.436753 3.045656 1.0646880 1363 Cellulase M and related proteins G aminopeptidase from family M42 2.342197e-04 8 5.239421e-03 1.273964e-03 1.694568e-02 3.222977e-02 4.275534e-01 0 8 30 TRUE TRUE 117 TRUE 0.4469764 0.2130140 0.5480306 0.4469764 0.7652913 0.4451176 0.5174327 0.5078084 N 0.5492530 0.5384611 13773 129 182951 182952 1 1 Convergent + - 0.000000 0 0.000000 -1.99129640 1.436753 3.045656 1.0646880 1363 Cellulase M and related proteins G aminopeptidase from family M42 1.493771 3.227166 1.0558005 704 Phosphate uptake regulator P phosphate transport system regulator, conjectural 4.511578e-02 18 3.251040e-03 -6.203946e-04 1.750042e-02 -2.130982e-02 2.589037e-01 0 30 18 TRUE TRUE 118 FALSE 0.4469764 0.1964042 0.5480306 0.4469764 0.7781393 0.8268968 0.5149450 0.5586400 N 0.5492530 0.5331976 13773 129 182952 182953 1 81 Same - - 0.000000 0 0.000000 0.00000000 1.493771 3.227166 1.0558005 704 Phosphate uptake regulator P phosphate transport system regulator, conjectural 1.404020 3.081816 1.0616715 - - - paREP1 0.000000e+00 0 8.055341e-03 -2.007599e-03 -1.597352e-03 -1.743853e-01 7.049297e-01 18 0 FALSE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4719743 0.4643453 U 0.4686274 0.6162291 13773 129 182953 182954 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.404020 3.081816 1.0616715 - - - paREP1 1.427601 3.341945 1.1546994 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 0.000000e+00 0 5.560577e-04 1.127106e-03 2.965448e-02 5.436890e-02 5.407499e-02 0 41 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187547 0.6225521 U 0.4686274 0.6162291 13773 129 182954 182955 1 -9 Same - - 22.613200 0 43.215236 42.43697819 1.427601 3.341945 1.1546994 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.450591 3.193094 1.0693310 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 9.059973e-02 24 5.285628e-04 1.907292e-05 1.952480e-02 -1.273406e-02 5.407499e-02 E 41 24 FALSE TRUE 115 TRUE 2.2870605 2.0325179 0.5480306 2.2151785 0.7769228 0.9801540 0.5175642 0.6225521 Y 1.4497162 0.9333600 13773 129 182955 182956 1 -12 Same - - 10.199138 0 10.199138 10.19913779 1.450591 3.193094 1.0693310 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.410890 3.317730 1.1690383 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 1.015478e-02 8 1.576151e-03 3.246868e-05 2.528162e-02 -2.695827e-02 1.550051e-01 E 24 8 FALSE TRUE 114 TRUE 2.6745147 1.8413297 0.5480306 2.7563279 0.7652913 0.5985623 0.5130644 0.5915122 Y 1.4497162 0.9127634 13773 129 182956 182957 1 -3 Same - - 11.403111 0 11.403111 11.40311060 1.410890 3.317730 1.1690383 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 1.487714 3.610289 1.1972632 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 3.340200e-02 8 5.901799e-03 -1.471078e-03 2.721615e-03 -1.310407e-01 5.394299e-01 E 8 26 FALSE TRUE 113 TRUE 2.6320404 1.8616422 0.5480306 2.7155857 0.7652913 0.7621800 0.4813751 0.4851972 Y 1.4497162 0.9152118 13773 129 182957 182958 1 0 Same - - 0.000000 0 0.000000 -0.21357410 1.487714 3.610289 1.1972632 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 1.375830 3.065874 1.0892543 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 2.896808e-02 2 1.251791e-02 -2.744494e-03 -2.019222e-04 -2.670200e-01 1.105484e+00 E 26 2 FALSE TRUE 112 TRUE 0.4469764 0.2704329 0.5480306 0.4469764 0.6838149 0.7259260 0.4478311 0.4323983 Y 1.4497162 0.6507898 13773 129 182958 182959 1 122 Same - - 0.000000 0 0.000000 -0.30058548 1.375830 3.065874 1.0892543 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 1.432209 3.229342 1.0977193 1117 ABC-type phosphate transport system, ATPase component P phosphate ABC transporter, ATP-binding protein 6.217154e-03 2 3.178543e-03 1.449605e-03 2.412161e-02 5.541024e-02 2.844990e-01 0 2 59 FALSE TRUE 111 TRUE 0.4469764 0.2544953 0.5480306 0.4469764 0.6838149 0.5596796 0.5187138 0.5488286 N 0.5492530 0.5515662 13773 129 182959 182960 1 39 Same - - 47.019214 0 87.522171 86.27552270 1.432209 3.229342 1.0977193 1117 ABC-type phosphate transport system, ATPase component P phosphate ABC transporter, ATP-binding protein 1.330439 3.072935 1.0753204 581 ABC-type phosphate transport system, permease component P phosphate ABC transporter, permease protein 1.012596e-01 26 1.035718e-02 2.320404e-03 8.408679e-02 7.734203e-02 6.079930e-01 P 59 26 FALSE TRUE 110 TRUE 2.0684664 2.0720448 0.5480306 2.0631503 0.7764129 1.0202977 0.5178295 0.4757686 Y 1.4497162 0.9380194 13773 129 182960 182961 1 -3 Same - - 18.095690 0 40.248561 40.24856069 1.330439 3.072935 1.0753204 581 ABC-type phosphate transport system, permease component P phosphate ABC transporter, permease protein 1.396074 3.447193 1.1804258 573 ABC-type phosphate transport system, permease component P phosphate ABC transporter, permease protein 2.017586e-02 10 4.308002e-03 6.691070e-03 6.959004e-02 3.973780e-01 1.692157e-01 P 26 10 FALSE TRUE 109 TRUE 2.4895052 2.0151334 0.5480306 2.2776779 0.7739415 0.6826809 0.6326930 0.5878822 Y 1.4497162 0.9303602 13773 129 182961 182962 1 23 Same - - 19.705128 0 43.850429 43.85042877 1.396074 3.447193 1.1804258 573 ABC-type phosphate transport system, permease component P phosphate ABC transporter, permease protein 1.400915 3.042005 1.0869453 226 ABC-type phosphate transport system, periplasmic component P phosphate-binding periplasmic protein, putative 6.972357e-02 10 2.343611e-05 2.792385e-03 5.208637e-02 1.874557e-01 2.264094e-03 P 10 19 FALSE TRUE 108 TRUE 2.3867167 2.0346988 0.5480306 2.2071487 0.7739415 0.9130389 0.5450862 0.6496996 Y 1.4497162 0.9327618 13773 129 182962 182963 1 146 Divergent - + 0.000000 0 0.000000 0.00000000 1.400915 3.042005 1.0869453 226 ABC-type phosphate transport system, periplasmic component P phosphate-binding periplasmic protein, putative 1.401285 3.003545 1.0640064 - - - hypothetical protein 0.000000e+00 0 1.370616e-07 2.529329e-03 5.021675e-02 1.663827e-01 1.472486e-05 19 0 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5372013 0.6556702 U 0.4686274 0.6162291 13773 129 182963 182964 1 369 Same + + 0.000000 0 0.000000 0.00000000 1.401285 3.003545 1.0640064 - - - hypothetical protein 1.298024 2.625571 0.9152419 - - - conserved hypothetical protein 0.000000e+00 0 1.066289e-02 7.684959e-03 1.639506e-01 3.851105e-01 2.944083e-01 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6276371 0.5440712 U 0.4686274 0.6162291 13773 129 182964 182965 1 161 Same + + 0.000000 0 0.000000 0.00000000 1.298024 2.625571 0.9152419 - - - conserved hypothetical protein 1.406619 2.983106 1.0009545 - - - hypothetical protein 0.000000e+00 0 1.179290e-02 6.866909e-03 4.638405e-02 3.268707e-01 3.648049e-01 0 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6026224 0.5200138 U 0.4686274 0.6162291 13773 129 182965 182966 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.406619 2.983106 1.0009545 - - - hypothetical protein 1.350831 2.882962 1.0283434 - - - conserved within P. aerophilum 0.000000e+00 0 3.112354e-03 4.502555e-03 9.397336e-02 2.657808e-01 1.820794e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5760302 0.5845929 U 0.4686274 0.6162291 13773 129 182966 182967 1 121 Same + + 0.000000 0 0.000000 0.00000000 1.350831 2.882962 1.0283434 - - - conserved within P. aerophilum 1.427344 3.179429 1.0575409 - - - hypothetical protein 0.000000e+00 0 5.854330e-03 2.418390e-03 2.480140e-02 1.130604e-01 3.902653e-01 0 0 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5203882 0.5139757 U 0.4686274 0.6162291 13773 129 182967 182968 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.427344 3.179429 1.0575409 - - - hypothetical protein 1.429364 3.487701 1.1304809 - - - hypothetical protein 0.000000e+00 0 4.079856e-06 5.297638e-04 2.669548e-02 1.811217e-02 5.300950e-04 0 0 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177867 0.6531640 U 0.4686274 0.6162291 13773 129 182968 182969 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.429364 3.487701 1.1304809 - - - hypothetical protein 1.470264 3.542717 1.1559670 - - - hypothetical protein 0.000000e+00 0 1.672809e-03 -4.157095e-04 1.554913e-02 -3.366398e-02 1.568233e-01 0 0 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5108846 0.5907175 U 0.4686274 0.6162291 13773 129 182969 182970 1 815 Convergent + - 0.000000 0 0.000000 0.00000000 1.470264 3.542717 1.1559670 - - - hypothetical protein 1.676700 3.451697 1.1080663 - - - paREP6, authentic frameshift 0.000000e+00 0 4.261576e-02 4.251808e-03 1.984604e-01 2.605299e-01 4.675915e-01 0 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5740192 0.4996268 U 0.4686274 0.6162291 13773 129 182970 182971 1 241 Divergent - + 0.000000 0 0.000000 0.00000000 1.676700 3.451697 1.1080663 - - - paREP6, authentic frameshift 1.469320 3.619400 1.1930264 - - - hypothetical protein 0.000000e+00 0 4.300655e-02 4.039038e-03 -6.013437e-02 2.531910e-01 4.781462e-01 0 0 FALSE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5707698 0.4970610 U 0.4686274 0.6162291 13773 129 182971 182972 1 215 Same + + 0.000000 0 0.000000 0.00000000 1.469320 3.619400 1.1930264 - - - hypothetical protein 1.546951 3.549690 1.0811025 - - - hypothetical protein 0.000000e+00 0 6.026644e-03 1.713056e-03 6.314033e-02 1.948717e-01 2.220485e-01 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5480452 0.5735582 U 0.4686274 0.6162291 13773 129 182972 182973 1 282 Convergent + - 0.000000 0 0.000000 0.00000000 1.546951 3.549690 1.0811025 - - - hypothetical protein 1.611163 3.273207 0.9280749 - - - hypothetical protein 0.000000e+00 0 4.123161e-03 1.526736e-02 2.408834e-01 6.518319e-01 2.239651e-02 0 0 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7374439 0.6365803 U 0.4686274 0.6162291 13773 129 182973 182974 1 -25 Same - - 0.000000 0 0.000000 0.00000000 1.611163 3.273207 0.9280749 - - - hypothetical protein 1.690921 3.648498 1.0978687 - - - hypothetical protein 0.000000e+00 0 6.361282e-03 3.826938e-02 5.490699e-01 8.557417e-01 6.493663e-03 0 0 FALSE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7955742 0.6450314 U 0.4686274 0.6162291 13773 129 182974 182975 1 185 Divergent - + 0.000000 0 0.000000 0.00000000 1.690921 3.648498 1.0978687 - - - hypothetical protein 1.520748 3.685754 1.1641223 - - - hypothetical protein 0.000000e+00 0 2.895883e-02 1.661241e-02 8.148920e-02 6.065830e-01 1.145482e-01 0 0 FALSE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7226309 0.6020917 U 0.4686274 0.6162291 13773 129 182975 182976 1 -19 Same + + 0.000000 0 0.000000 0.00000000 1.520748 3.685754 1.1641223 - - - hypothetical protein 1.481775 3.394757 1.0675836 - - - hypothetical protein 0.000000e+00 0 1.518904e-03 2.107118e-03 3.550352e-02 2.384897e-01 6.144920e-02 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5640447 0.6199051 U 0.4686274 0.6162291 13773 129 182976 182977 1 -26 Convergent + - 0.000000 0 0.000000 0.00000000 1.481775 3.394757 1.0675836 - - - hypothetical protein 1.515789 3.621809 1.2193998 1966 Carbon starvation protein, predicted membrane protein T carbon starvation protein A homolog 0.000000e+00 0 1.156960e-03 1.956455e-03 5.179991e-02 2.277023e-01 4.817739e-02 0 10 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5609786 0.6245582 U 0.4686274 0.6162291 13773 129 182977 182978 1 74 Divergent - + 0.000000 0 0.000000 0.00000000 1.515789 3.621809 1.2193998 1966 Carbon starvation protein, predicted membrane protein T carbon starvation protein A homolog 1.391368 3.039794 1.0241503 - - - hypothetical protein 0.000000e+00 0 1.548051e-02 -3.865352e-03 -2.583816e-02 -2.939430e-01 1.187648e+00 10 0 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4422193 0.4288368 U 0.4686274 0.6162291 13773 129 182978 182979 1 223 Same + + 0.000000 0 0.000000 0.00000000 1.391368 3.039794 1.0241503 - - - hypothetical protein 1.671911 3.754420 1.1116133 3 Oxyanion-translocating ATPase P arsenical pump-driving ATPase 0.000000e+00 0 7.870438e-02 -1.323657e-02 -1.968602e-02 -4.670720e-01 2.081742e+00 0 7 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4093136 0.4073179 U 0.4686274 0.6162291 13773 129 182979 182980 1 275 Convergent + - 0.000000 0 0.000000 0.00000000 1.671911 3.754420 1.1116133 3 Oxyanion-translocating ATPase P arsenical pump-driving ATPase 1.475642 3.051429 1.1456119 - - - hypothetical protein 0.000000e+00 0 3.852161e-02 5.347319e-03 -3.873855e-02 3.113813e-01 3.912248e-01 7 0 TRUE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5971763 0.5136669 U 0.4686274 0.6162291 13773 129 182980 182981 1 296 Same - - 0.000000 0 0.000000 0.00000000 1.475642 3.051429 1.1456119 - - - hypothetical protein 1.372301 3.366729 1.0768025 - - - conserved within P. aerophilum 0.000000e+00 0 1.067941e-02 -1.917901e-03 1.270594e-02 -2.100130e-01 9.395456e-01 0 0 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4616204 0.4435238 U 0.4686274 0.6162291 13773 129 182981 182982 1 164 Divergent - + 0.000000 0 0.000000 0.00000000 1.372301 3.366729 1.0768025 - - - conserved within P. aerophilum 1.712325 3.897075 1.1201774 - - - P. aerophilum family 321 protein 0.000000e+00 0 1.156165e-01 -2.063771e-02 -6.354674e-02 -6.251092e-01 2.609849e+00 0 0 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3919466 0.4027255 U 0.4686274 0.6162291 13773 129 182982 182983 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.712325 3.897075 1.1201774 - - - P. aerophilum family 321 protein 1.471451 3.511123 1.1837908 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 1, authentic frameshift 0.000000e+00 0 5.802032e-02 5.233718e-03 -8.995011e-02 2.718515e-01 4.813357e-01 0 0 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5809077 0.4963031 U 0.4686274 0.6162291 13773 129 182983 182984 1 43 Same + + 0.000000 0 0.000000 0.00000000 1.471451 3.511123 1.1837908 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 1, authentic frameshift 1.432841 3.414053 1.1321474 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 2, authentic frameshift 0.000000e+00 0 1.490714e-03 -3.721115e-04 1.623921e-02 -2.143940e-02 1.268081e-01 0 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5148089 0.5988589 U 0.4686274 0.6162291 13773 129 182984 182985 1 229 Convergent + - 0.000000 0 0.000000 0.00000000 1.432841 3.414053 1.1321474 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 2, authentic frameshift 1.310032 2.893772 0.9805899 - - - hypothetical protein 0.000000e+00 0 1.508192e-02 2.622514e-03 1.012733e-01 7.079713e-02 7.152772e-01 0 0 TRUE TRUE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180874 0.4631357 U 0.4686274 0.6162291 13773 129 182985 182986 1 22 Same - - 0.000000 0 0.000000 0.00000000 1.310032 2.893772 0.9805899 - - - hypothetical protein 1.606539 3.507720 1.1069389 - - - paREP10 0.000000e+00 0 8.791635e-02 -2.193157e-02 -2.253118e-01 -8.077952e-01 3.233373e+00 0 0 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3824855 0.4002962 U 0.4686274 0.6162291 13773 129 182986 182987 1 147 Divergent - + 0.000000 0 0.000000 0.00000000 1.606539 3.507720 1.1069389 - - - paREP10 1.601012 3.599903 1.0870614 - - - hypothetical protein 0.000000e+00 0 3.055611e-05 2.321282e-02 2.878702e-01 7.580641e-01 9.954005e-05 0 0 FALSE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7698915 0.6550803 U 0.4686274 0.6162291 13773 129 182987 182988 1 506 Convergent + - 0.000000 0 0.000000 0.00000000 1.601012 3.599903 1.0870614 - - - hypothetical protein 1.439780 3.114049 1.0629517 1056 Nicotinamide mononucleotide adenylyltransferase H cytidylyltransferase 0.000000e+00 0 2.599576e-02 -1.737567e-03 -5.608477e-02 -9.965785e-03 7.694912e-01 0 10 TRUE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186744 0.4579043 U 0.4686274 0.6162291 13773 129 182988 182989 1 415 Same - - 0.000000 0 0.000000 -0.90107974 1.439780 3.114049 1.0629517 1056 Nicotinamide mononucleotide adenylyltransferase H cytidylyltransferase 1.413560 3.048733 1.0834067 16 Phenylalanyl-tRNA synthetase alpha subunit J phenylalanyl-tRNA synthetase alpha subunit 1.890957e-01 10 6.874424e-04 4.393591e-04 2.916708e-02 3.198240e-03 7.092023e-02 0 10 11 FALSE TRUE 115 TRUE 0.4469764 0.2149923 0.5480306 0.4469764 0.7739415 1.1270741 0.5197020 0.6175203 N 0.5492530 0.5390874 13773 129 182989 182990 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.413560 3.048733 1.0834067 16 Phenylalanyl-tRNA synthetase alpha subunit J phenylalanyl-tRNA synthetase alpha subunit 1.344734 2.959863 1.0258603 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 0.000000e+00 0 4.737134e-03 4.035178e-03 9.317329e-02 2.253693e-01 2.844990e-01 0 11 0 FALSE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5598594 0.5488286 N 0.5492530 0.6245624 13773 129 182990 182991 1 25 Same - - 0.000000 0 0.000000 0.00000000 1.344734 2.959863 1.0258603 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 1.360988 2.969464 0.9967276 - - - hypothetical protein 0.000000e+00 0 2.642154e-04 9.642482e-03 1.253457e-01 5.814777e-01 8.910896e-03 0 0 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7135880 0.6435760 U 0.4686274 0.6162291 13773 129 182991 182992 1 37 Same - - 0.000000 0 0.000000 0.00000000 1.360988 2.969464 0.9967276 - - - hypothetical protein 1.293059 2.833885 1.0068171 4046 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 4.614367e-03 1.431409e-02 2.310110e-01 6.860006e-01 5.770319e-02 0 5 FALSE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7483293 0.6211938 U 0.4686274 0.6162291 13773 129 182992 182993 1 110 Same - - 0.000000 0 0.000000 0.00000000 1.293059 2.833885 1.0068171 4046 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.431678 3.162982 1.0867045 - - - hypothetical protein 0.000000e+00 0 1.921512e-02 3.121562e-03 -5.441423e-03 9.107503e-02 7.427979e-01 5 0 FALSE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178515 0.4602020 U 0.4686274 0.6162291 13773 129 182993 182994 1 62 Divergent - + 0.000000 0 0.000000 0.00000000 1.431678 3.162982 1.0867045 - - - hypothetical protein 1.385930 3.491610 1.1477299 - - - hypothetical protein 0.000000e+00 0 2.092863e-03 1.290607e-03 4.572355e-02 5.163596e-02 2.001927e-01 0 0 FALSE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187846 0.5800294 U 0.4686274 0.6162291 13773 129 182994 182995 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.385930 3.491610 1.1477299 - - - hypothetical protein 1.363081 3.046021 1.0742640 1196 Chromosome segregation ATPases D hypothetical protein 0.000000e+00 0 5.220864e-04 5.781167e-03 9.725563e-02 3.831055e-01 2.672209e-02 0 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6261711 0.6346538 U 0.4686274 0.6162291 13773 129 182995 182996 1 36 Same - - 0.000000 0 0.000000 0.00000000 1.363081 3.046021 1.0742640 1196 Chromosome segregation ATPases D hypothetical protein 1.398737 3.041175 1.0351818 - - - hypothetical protein 0.000000e+00 0 1.271367e-03 4.650152e-03 6.234402e-02 3.056174e-01 7.464679e-02 0 0 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5938727 0.6164920 U 0.4686274 0.6162291 13773 129 182996 182997 1 121 Same - - 0.000000 0 0.000000 0.00000000 1.398737 3.041175 1.0351818 - - - hypothetical protein 1.273536 2.621002 1.0311313 - - - paREP2a 0.000000e+00 0 1.567516e-02 9.365185e-03 2.035289e-01 4.222171e-01 2.944083e-01 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6453590 0.5440712 U 0.4686274 0.6162291 13773 129 182997 182998 1 147 Same - - 0.000000 0 0.000000 0.00000000 1.273536 2.621002 1.0311313 - - - paREP2a 1.809876 3.811674 1.1584036 - - - paREP2a 0.000000e+00 0 2.876600e-01 -6.375850e-02 -4.787240e-01 -9.679552e-01 3.872106e+00 0 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3776941 0.3989272 U 0.4686274 0.6162291 13773 129 182998 182999 1 250 Same - - 0.000000 0 0.000000 0.00000000 1.809876 3.811674 1.1584036 - - - paREP2a 1.399627 3.098597 1.0950888 - - - paREP9, associated with SRSRs, authentic frameshift 0.000000e+00 0 1.683043e-01 -1.855725e-02 -5.157863e-01 -4.211481e-01 2.007126e+00 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4150208 0.4080068 U 0.4686274 0.6162291 13773 129 182999 183000 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.399627 3.098597 1.0950888 - - - paREP9, associated with SRSRs, authentic frameshift 1.612936 3.774628 1.1628738 - - - hypothetical protein 0.000000e+00 0 4.550064e-02 -8.362427e-03 -1.757214e-02 -3.768510e-01 1.722279e+00 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4235173 0.4119763 U 0.4686274 0.6162291 13773 129 183000 183001 1 152 Divergent - + 0.000000 0 0.000000 0.00000000 1.612936 3.774628 1.1628738 - - - hypothetical protein 1.407081 3.020865 1.0636785 - - - hypothetical protein 0.000000e+00 0 4.237629e-02 -7.158324e-03 -1.242441e-01 -2.991638e-01 1.500296e+00 0 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4405807 0.4170968 U 0.4686274 0.6162291 13773 129 183001 183002 1 119 Same + + 0.000000 0 0.000000 0.00000000 1.407081 3.020865 1.0636785 - - - hypothetical protein 1.226436 2.658435 0.9939651 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein, part 1 authentic frameshift 0.000000e+00 0 3.263230e-02 9.968323e-03 2.608164e-01 3.358805e-01 4.356203e-01 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6074025 0.5060722 U 0.4686274 0.6162291 13773 129 183002 183003 1 64 Same + + 0.000000 0 0.000000 0.00000000 1.226436 2.658435 0.9939651 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein, part 1 authentic frameshift 1.345639 2.905036 1.0418545 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein, part 2 authentic frameshift 0.000000e+00 0 1.420922e-02 2.379002e-02 1.987861e-01 8.033589e-01 3.651824e-02 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7875319 0.6293389 U 0.4686274 0.6162291 13773 129 183003 183004 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.345639 2.905036 1.0418545 1673 Uncharacterized protein conserved in archaea S conserved hypothetical protein, part 2 authentic frameshift 1.340534 2.727959 1.0288098 - - - conserved within P. aerophilum 0.000000e+00 0 2.605781e-05 1.172373e-02 1.606229e-01 6.685381e-01 5.660236e-04 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7435095 0.6530578 U 0.4686274 0.6162291 13773 129 183004 183005 1 821 Same + + 0.000000 0 0.000000 0.00000000 1.340534 2.727959 1.0288098 - - - conserved within P. aerophilum 1.468181 3.058219 1.0625454 110 Acetyltransferase (isoleucine patch superfamily) R acetyl/acyl transferase related protein 0.000000e+00 0 1.629382e-02 -1.861163e-03 -3.151740e-02 -2.075652e-01 1.166002e+00 0 2 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4622093 0.4298977 U 0.4686274 0.6162291 13773 129 183005 183006 1 41 Convergent + - 0.000000 0 0.000000 0.00000000 1.468181 3.058219 1.0625454 110 Acetyltransferase (isoleucine patch superfamily) R acetyl/acyl transferase related protein 1.335638 2.842147 1.0012132 1363 Cellulase M and related proteins G aminopeptidase from family M42 1.134242e-03 2 1.756769e-02 -1.943359e-03 3.132677e-02 -2.133255e-01 1.216255e+00 2 3 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4743646 0.4605811 0.4276782 U 0.4686274 0.6162291 13773 129 183006 183007 1 61 Divergent - + 0.000000 0 0.000000 -0.13353139 1.335638 2.842147 1.0012132 1363 Cellulase M and related proteins G aminopeptidase from family M42 1.353422 2.925661 1.0272395 2820 Uridine phosphorylase F purine nucleoside phosphorylase 1.545090e-03 3 3.162515e-04 1.134059e-02 1.436830e-01 6.471747e-01 8.766593e-03 0 3 16 FALSE TRUE 109 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.7136133 0.4847788 0.7357254 0.6436550 N 0.5492530 0.5604716 13773 129 183007 183008 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.353422 2.925661 1.0272395 2820 Uridine phosphorylase F purine nucleoside phosphorylase 1.523015 3.348962 1.1204094 - - - hypothetical protein 0.000000e+00 0 2.876185e-02 -7.016897e-03 -7.265388e-02 -4.834878e-01 1.948842e+00 16 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4073074 0.4089996 U 0.4686274 0.6162291 13773 129 183008 183009 1 533 Divergent - + 0.000000 0 0.000000 0.00000000 1.523015 3.348962 1.1204094 - - - hypothetical protein 1.467411 3.678664 1.2303769 2431 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 3.091854e-03 1.147221e-03 2.177588e-02 1.554592e-01 1.544013e-01 0 0 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5325390 0.5918248 U 0.4686274 0.6162291 13773 129 183009 183010 1 47 Same + + 0.000000 0 0.000000 0.00000000 1.467411 3.678664 1.2303769 2431 Predicted membrane protein S conserved hypothetical protein 1.765850 3.983333 1.1951509 - - - paREP10 0.000000e+00 0 8.906602e-02 5.036876e-03 3.300935e-01 2.404935e-01 5.496237e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5652262 0.4836874 U 0.4686274 0.6162291 13773 129 183010 183011 1 10 Convergent + - 0.000000 0 0.000000 0.00000000 1.765850 3.983333 1.1951509 - - - paREP10 1.414557 3.216284 1.1227371 163 3-polyprenyl-4-hydroxybenzoate decarboxylase H phenylacrylic acid decarboxylase homolog 0.000000e+00 0 1.234068e-01 -1.158336e-02 -3.623671e-01 -2.601565e-01 1.561061e+00 0 38 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4501861 0.4153650 U 0.4686274 0.6162291 13773 129 183011 183012 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.414557 3.216284 1.1227371 163 3-polyprenyl-4-hydroxybenzoate decarboxylase H phenylacrylic acid decarboxylase homolog 1.404644 3.162329 1.0777213 - - - hypothetical protein 0.000000e+00 0 9.825768e-05 1.722033e-03 4.297625e-02 9.664691e-02 1.041872e-02 38 0 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181452 0.6425621 U 0.4686274 0.6162291 13773 129 183012 183013 1 35 Divergent - + 0.000000 0 0.000000 0.00000000 1.404644 3.162329 1.0777213 - - - hypothetical protein 1.434698 3.216302 1.0906587 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 0.000000e+00 0 9.032322e-04 7.804554e-04 2.502088e-02 2.331888e-02 9.143314e-02 0 0 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174318 0.6103141 U 0.4686274 0.6162291 13773 129 183013 183014 1 211 Same + + 0.000000 0 0.000000 0.00000000 1.434698 3.216302 1.0906587 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 1.430316 3.009829 1.0243015 2520 Predicted methyltransferase R conserved hypothetical protein 0.000000e+00 0 1.920021e-05 3.518676e-04 2.527213e-02 7.088548e-03 2.264094e-03 0 8 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192324 0.6496996 U 0.4686274 0.6162291 13773 129 183014 183015 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.430316 3.009829 1.0243015 2520 Predicted methyltransferase R conserved hypothetical protein 1.460312 3.212488 1.0856403 4755 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 8.997287e-04 -1.879802e-04 1.761368e-02 -2.041160e-02 8.685076e-02 8 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5152867 0.6122969 U 0.4686274 0.6162291 13773 129 183015 183016 1 80 Same - - 0.000000 0 0.000000 0.00000000 1.460312 3.212488 1.0856403 4755 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.395455 3.081282 1.0667224 794 Predicted sugar phosphate isomerase involved in capsule formation M conserved protein with sugar isomerase (SIS) domain 0.000000e+00 0 4.206436e-03 -4.989080e-04 2.264861e-02 -8.488411e-02 4.175758e-01 0 13 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4968247 0.5092380 U 0.4686274 0.6162291 13773 129 183016 183017 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.395455 3.081282 1.0667224 794 Predicted sugar phosphate isomerase involved in capsule formation M conserved protein with sugar isomerase (SIS) domain 1.438415 3.034388 1.0252955 1586 S-adenosylmethionine decarboxylase E conserved hypothetical protein 1.640963e-02 6 1.845542e-03 7.259842e-04 2.170754e-02 1.456171e-02 1.860303e-01 0 13 6 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7537284 0.6515847 0.5181737 0.5838164 N 0.5492530 0.6245624 13773 129 183017 183018 1 1083 Divergent - + 0.000000 0 0.000000 0.00000000 1.438415 3.034388 1.0252955 1586 S-adenosylmethionine decarboxylase E conserved hypothetical protein 1.470452 3.237298 1.0863996 - - - hypothetical protein 0.000000e+00 0 1.026378e-03 -2.473516e-04 1.834028e-02 -8.621111e-03 9.329907e-02 6 0 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190700 0.6097348 U 0.4686274 0.6162291 13773 129 183018 183019 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.470452 3.237298 1.0863996 - - - hypothetical protein 1.504103 3.097679 1.1198189 - - - hypothetical protein 0.000000e+00 0 1.132443e-03 1.004600e-03 3.861710e-02 1.459281e-01 6.689151e-02 0 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5293416 0.6185855 U 0.4686274 0.6162291 13773 129 183019 183020 1 48 Same + + 0.000000 0 0.000000 0.00000000 1.504103 3.097679 1.1198189 - - - hypothetical protein 1.388114 3.020473 1.0858427 1048 Aconitase A C aconitate hydratase 0.000000e+00 0 1.345353e-02 -3.335462e-03 -1.514854e-02 -2.746881e-01 1.099038e+00 0 39 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4461137 0.4327437 U 0.4686274 0.6162291 13773 129 183020 183021 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.388114 3.020473 1.0858427 1048 Aconitase A C aconitate hydratase 1.497322 3.924759 1.1983406 - - - conserved hypothetical protein 0.000000e+00 0 1.192641e-02 -2.906353e-03 -1.805581e-02 -2.521273e-01 1.009231e+00 39 0 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4516710 0.4388235 U 0.4686274 0.6162291 13773 129 183021 183022 1 43 Same + + 0.000000 0 0.000000 0.00000000 1.497322 3.924759 1.1983406 - - - conserved hypothetical protein 1.486456 3.297070 1.1269694 149 Triosephosphate isomerase G triosephosphate isomerase (tpiA) 0.000000e+00 0 1.180676e-04 1.610441e-03 3.733250e-02 2.048534e-01 4.877463e-03 0 13 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5514514 0.6464448 U 0.4686274 0.6162291 13773 129 183022 183023 1 55 Convergent + - 0.000000 0 0.000000 0.00000000 1.486456 3.297070 1.1269694 149 Triosephosphate isomerase G triosephosphate isomerase (tpiA) 1.477523 3.066349 1.0655464 - - - hypothetical protein 0.000000e+00 0 7.980786e-05 9.162050e-04 3.006194e-02 1.437512e-01 5.772734e-03 13 0 TRUE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5288141 0.6458271 U 0.4686274 0.6162291 13773 129 183023 183024 1 68 Divergent - + 0.000000 0 0.000000 0.00000000 1.477523 3.066349 1.0655464 - - - hypothetical protein 1.385536 3.115018 1.0482836 - - - hypothetical protein 0.000000e+00 0 8.461538e-03 -1.720830e-03 9.897470e-03 -1.877190e-01 7.925509e-01 0 0 FALSE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4679083 0.4565008 U 0.4686274 0.6162291 13773 129 183024 183025 1 657 Same + + 0.000000 0 0.000000 0.00000000 1.385536 3.115018 1.0482836 - - - hypothetical protein 1.358907 2.926221 1.0076296 2125 Ribosomal protein S6E (S10) J ribosomal protein S6 0.000000e+00 0 7.090929e-04 6.090790e-03 1.026607e-01 3.997953e-01 3.364395e-02 0 9 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6354153 0.6306472 U 0.4686274 0.6162291 13773 129 183025 183026 1 1 Convergent + - 0.000000 0 0.000000 -0.26225543 1.358907 2.926221 1.0076296 2125 Ribosomal protein S6E (S10) J ribosomal protein S6 1.378641 3.000680 1.0354653 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family 7.713639e-03 8 3.894334e-04 6.728453e-03 9.112782e-02 4.339993e-01 1.866170e-02 0 9 8 TRUE TRUE 114 FALSE 0.4469764 0.2625645 0.5480306 0.4469764 0.7652913 0.5769711 0.6491974 0.6383656 N 0.5492530 0.5541078 13773 129 183026 183027 1 74 Divergent - + 0.000000 0 0.000000 0.00000000 1.378641 3.000680 1.0354653 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family 1.494498 3.365521 1.1385007 - - - hypothetical protein 0.000000e+00 0 1.342277e-02 -3.135967e-03 -2.465140e-02 -2.785437e-01 1.129824e+00 8 0 FALSE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4454176 0.4314822 U 0.4686274 0.6162291 13773 129 183027 183028 1 91 Same + + 0.000000 0 0.000000 0.00000000 1.494498 3.365521 1.1385007 - - - hypothetical protein 1.483719 3.323961 1.1293493 - - - hypothetical protein 0.000000e+00 0 1.161884e-04 1.393427e-03 3.496520e-02 1.856958e-01 5.315674e-03 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5444769 0.6461561 U 0.4686274 0.6162291 13773 129 183028 183029 1 45 Same + + 0.000000 0 0.000000 0.00000000 1.483719 3.323961 1.1293493 - - - hypothetical protein 1.660699 3.660183 1.1088979 - - - hypothetical protein 0.000000e+00 0 3.132198e-02 6.766071e-03 2.084485e-01 3.719994e-01 2.952417e-01 0 0 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6209710 0.5436061 U 0.4686274 0.6162291 13773 129 183029 183030 1 537 Convergent + - 0.000000 0 0.000000 0.00000000 1.660699 3.660183 1.1088979 - - - hypothetical protein 1.378714 2.987713 1.0637360 532 Translation initiation factor 2 (IF-2; GTPase) J translation initiation factor IF-2 (infB), putative 0.000000e+00 0 7.951537e-02 -1.521204e-02 -2.549654e-01 -5.572782e-01 2.348915e+00 0 30 TRUE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3982199 0.4045574 U 0.4686274 0.6162291 13773 129 183030 183031 1 140 Same - - 0.000000 0 0.000000 0.00000000 1.378714 2.987713 1.0637360 532 Translation initiation factor 2 (IF-2; GTPase) J translation initiation factor IF-2 (infB), putative 1.449526 3.099691 1.0047854 - - - paREP2b 0.000000e+00 0 5.014267e-03 1.356811e-04 8.918909e-03 -4.598456e-02 4.499187e-01 30 0 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5076021 0.5038000 U 0.4686274 0.6162291 13773 129 183031 183032 1 139 Divergent - + 0.000000 0 0.000000 0.00000000 1.449526 3.099691 1.0047854 - - - paREP2b 1.400748 3.093083 1.0732087 - - - paREP8 0.000000e+00 0 2.379307e-03 9.454767e-05 2.834795e-02 -3.188580e-02 2.389957e-01 0 1 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5116101 0.5668045 U 0.4686274 0.6162291 13773 129 183032 183033 1 97 Same + + 0.000000 0 0.000000 0.00000000 1.400748 3.093083 1.0732087 - - - paREP8 1.403610 3.026879 1.1113284 - - - hypothetical protein 0.000000e+00 0 8.191606e-06 2.419966e-03 4.831721e-02 1.569034e-01 8.958605e-04 1 0 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5332136 0.6519767 U 0.4686274 0.6162291 13773 129 183033 183034 1 -11 Convergent + - 0.000000 0 0.000000 0.00000000 1.403610 3.026879 1.1113284 - - - hypothetical protein 1.387498 3.182457 1.0739115 - - - hypothetical protein 0.000000e+00 0 2.596046e-04 3.053097e-03 6.100491e-02 1.993493e-01 1.994099e-02 0 0 TRUE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5498106 0.6374861 U 0.4686274 0.6162291 13773 129 183034 183035 1 57 Divergent - + 0.000000 0 0.000000 0.00000000 1.387498 3.182457 1.0739115 - - - hypothetical protein 1.474565 3.169312 1.0811271 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 7.580732e-03 -1.480594e-03 -5.578011e-03 -1.632498e-01 6.972186e-01 0 0 FALSE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4738170 0.4651780 U 0.4686274 0.6162291 13773 129 183035 183036 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.474565 3.169312 1.0811271 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.401243 3.023381 1.0379035 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 0.000000e+00 0 5.376108e-03 -1.162081e-03 1.217357e-02 -1.270520e-01 5.171188e-01 0 2 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4825884 0.4904415 U 0.4686274 0.6162291 13773 129 183036 183037 1 79 Convergent + - 0.000000 0 0.000000 0.00000000 1.401243 3.023381 1.0379035 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 1.480009 3.593074 1.1829549 - - - hypothetical protein 0.000000e+00 0 6.204081e-03 -1.435098e-03 -3.491467e-04 -1.485915e-01 5.960835e-01 2 0 TRUE TRUE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4771554 0.4771498 U 0.4686274 0.6162291 13773 129 183037 183038 1 72 Divergent - + 0.000000 0 0.000000 0.00000000 1.480009 3.593074 1.1829549 - - - hypothetical protein 1.402013 3.480707 1.1993508 - - - hypothetical protein 0.000000e+00 0 6.083397e-03 -1.413068e-03 8.328387e-03 -1.449468e-01 5.807773e-01 0 0 FALSE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4789116 0.4797254 U 0.4686274 0.6162291 13773 129 183038 183039 1 145 Same + + 0.000000 0 0.000000 0.00000000 1.402013 3.480707 1.1993508 - - - hypothetical protein 1.405091 3.037649 1.0338757 2178 Predicted RNA-binding protein of the translin family J conserved hypothetical protein 0.000000e+00 0 9.474719e-06 2.286374e-03 4.672268e-02 1.434243e-01 1.246312e-03 0 5 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5285509 0.6515199 U 0.4686274 0.6162291 13773 129 183039 183040 1 127 Same + + 0.000000 0 0.000000 -0.27466109 1.405091 3.037649 1.0338757 2178 Predicted RNA-binding protein of the translin family J conserved hypothetical protein 1.412092 3.076504 1.0906672 154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases J Glu-tRNA(Gln) amidotransferase subunit A (gatA) 1.907648e-04 5 4.900948e-05 1.819709e-03 4.049236e-02 1.056956e-01 4.770855e-03 J 5 47 TRUE TRUE 118 TRUE 0.4469764 0.2574924 0.5480306 0.4469764 0.7448207 0.4435235 0.5193380 0.6465274 Y 1.4497162 0.6470335 13773 129 183040 183041 1 -18 Convergent + - 0.000000 0 0.000000 -0.24929257 1.412092 3.076504 1.0906672 154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases J Glu-tRNA(Gln) amidotransferase subunit A (gatA) 1.489381 3.325145 1.1264828 491 Zn-dependent hydrolases, including glyoxylases R conserved hypothetical protein 1.889125e-02 3 5.973648e-03 -1.492981e-03 3.023668e-03 -1.288095e-01 5.371776e-01 47 3 TRUE TRUE 119 FALSE 0.4469764 0.2655387 0.5480306 0.4469764 0.7136133 0.6690864 0.4822256 0.4855756 U 0.4686274 0.5462885 13773 129 183041 183042 1 290 Divergent - + 0.000000 0 0.000000 0.00000000 1.489381 3.325145 1.1264828 491 Zn-dependent hydrolases, including glyoxylases R conserved hypothetical protein 1.588313 3.547071 1.1872648 - - - hypothetical protein 0.000000e+00 0 9.787574e-03 5.201377e-03 1.254976e-01 3.725672e-01 1.642022e-01 3 0 FALSE TRUE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6221162 0.5889325 U 0.4686274 0.6162291 13773 129 183042 183043 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.588313 3.547071 1.1872648 - - - hypothetical protein 1.537602 3.509450 1.1113181 - - - conserved within P. aerophilum, partially with both neighbors 0.000000e+00 0 2.571618e-03 1.180383e-02 1.300164e-01 5.958479e-01 1.994099e-02 0 0 TRUE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7189058 0.6374861 U 0.4686274 0.6162291 13773 129 183043 183044 1 33 Same + + 0.000000 0 0.000000 0.00000000 1.537602 3.509450 1.1113181 - - - conserved within P. aerophilum, partially with both neighbors 1.570903 3.975249 1.1624089 - - - conserved within P. aerophilum 0.000000e+00 0 1.108933e-03 1.030288e-02 1.585990e-01 5.682724e-01 1.041872e-02 0 0 TRUE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7067484 0.6425621 U 0.4686274 0.6162291 13773 129 183044 183045 1 560 Convergent + - 0.000000 0 0.000000 0.00000000 1.570903 3.975249 1.1624089 - - - conserved within P. aerophilum 1.450757 3.200797 1.0913033 - - - hypothetical protein 0.000000e+00 0 1.443493e-02 -7.594382e-05 -1.642013e-02 7.304591e-02 5.127131e-01 0 0 TRUE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179659 0.4912800 U 0.4686274 0.6162291 13773 129 183045 183046 1 79 Same - - 0.000000 0 0.000000 0.00000000 1.450757 3.200797 1.0913033 - - - hypothetical protein 1.462853 3.198318 1.0717831 2453 Predicted protein-tyrosine phosphatase T conserved protein (possible dual specificity phosphatase) 0.000000e+00 0 1.462985e-04 -7.282327e-06 2.098503e-02 1.883486e-02 1.378777e-02 0 3 FALSE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177390 0.6411621 U 0.4686274 0.6162291 13773 129 183046 183047 1 272 Same - - 0.000000 0 0.000000 0.00000000 1.462853 3.198318 1.0717831 2453 Predicted protein-tyrosine phosphatase T conserved protein (possible dual specificity phosphatase) 1.395874 3.314260 1.1549272 785 Cytochrome c biogenesis protein O hypothetical protein 5.631536e-04 1 4.486127e-03 -6.362396e-04 2.079266e-02 -9.545126e-02 4.447856e-01 0 3 1 FALSE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.4935866 0.5049034 N 0.5492530 0.6245624 13773 129 183047 183048 1 16 Divergent - + 0.000000 0 0.000000 0.00000000 1.395874 3.314260 1.1549272 785 Cytochrome c biogenesis protein O hypothetical protein 1.441085 3.112797 1.0582827 491 Zn-dependent hydrolases, including glyoxylases R conserved protein (possibly metallo-beta-lactamase superfamily) 6.187090e-03 1 2.044037e-03 5.722639e-04 1.987100e-02 1.056656e-03 2.085187e-01 1 47 FALSE TRUE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5584552 0.5198799 0.5767479 U 0.4686274 0.6162291 13773 129 183048 183049 1 20 Same + + 0.000000 0 0.000000 0.00000000 1.441085 3.112797 1.0582827 491 Zn-dependent hydrolases, including glyoxylases R conserved protein (possibly metallo-beta-lactamase superfamily) 1.336052 3.093302 1.0972261 - - - hypothetical protein 0.000000e+00 0 1.103189e-02 1.188883e-03 6.815275e-02 1.959584e-03 7.204792e-01 47 0 TRUE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198176 0.4629446 U 0.4686274 0.6162291 13773 129 183049 183050 1 25 Same + + 0.000000 0 0.000000 0.00000000 1.336052 3.093302 1.0972261 - - - hypothetical protein 1.502566 3.240328 1.1128651 665 Glycine/D-amino acid oxidases (deaminating) E conserved hypothetical protein 0.000000e+00 0 2.772670e-02 -5.902309e-03 -7.540775e-02 -4.441725e-01 1.885089e+00 0 1 TRUE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4126228 0.4098218 U 0.4686274 0.6162291 13773 129 183050 183051 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.502566 3.240328 1.1128651 665 Glycine/D-amino acid oxidases (deaminating) E conserved hypothetical protein 1.687020 3.769189 1.1585417 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 0.000000e+00 0 3.402318e-02 1.205771e-02 2.960631e-01 5.030483e-01 1.954142e-01 0 1 0 TRUE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6735615 0.5811598 N 0.5492530 0.6245624 13773 129 183051 183052 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.687020 3.769189 1.1585417 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 1.448122 3.552377 1.2030935 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 0.000000e+00 0 5.707224e-02 -7.707982e-04 -1.292409e-01 6.288104e-02 8.076533e-01 0 2 TRUE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183717 0.4542712 U 0.4686274 0.6162291 13773 129 183052 183053 1 36 Convergent + - 0.000000 0 0.000000 0.00000000 1.448122 3.552377 1.2030935 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.594577 3.459242 1.0468884 1826 Sec-independent protein secretion pathway components U conserved hypothetical protein 7.508473e-04 2 2.144907e-02 -4.683925e-04 6.729789e-02 5.597214e-02 6.285094e-01 2 2 TRUE TRUE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4618072 0.5186995 0.4734023 U 0.4686274 0.6162291 13773 129 183053 183054 1 67 Divergent - + 0.000000 0 0.000000 0.00000000 1.594577 3.459242 1.0468884 1826 Sec-independent protein secretion pathway components U conserved hypothetical protein 1.571135 3.666243 1.1471694 805 Sec-independent protein secretion pathway component TatC U membrane protein (mttB family) 6.687249e-03 2 5.494982e-04 1.714516e-02 2.055518e-01 6.927375e-01 2.565660e-03 U 2 16 FALSE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5679838 0.7505356 0.6491703 Y 1.4497162 0.7118045 13773 129 183054 183055 1 -15 Convergent + - 0.000000 0 0.000000 0.00000000 1.571135 3.666243 1.1471694 805 Sec-independent protein secretion pathway component TatC U membrane protein (mttB family) 1.472165 3.388388 1.1256048 - - - hypothetical protein 0.000000e+00 0 9.795042e-03 2.487343e-03 1.450412e-02 2.286406e-01 2.747594e-01 16 0 TRUE TRUE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5615444 0.5525016 U 0.4686274 0.6162291 13773 129 183055 183056 1 31 Divergent - + 0.000000 0 0.000000 0.00000000 1.472165 3.388388 1.1256048 - - - hypothetical protein 1.432892 3.172379 1.0707892 - - - hypothetical protein 0.000000e+00 0 1.542398e-03 -3.843096e-04 1.601768e-02 -2.151655e-02 1.290039e-01 0 0 FALSE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5147410 0.5983751 U 0.4686274 0.6162291 13773 129 183056 183057 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.432892 3.172379 1.0707892 - - - hypothetical protein 1.430229 3.527537 1.2028116 477 Permeases of the major facilitator superfamily GEPR transport protein, conjectural 0.000000e+00 0 7.090989e-06 3.915500e-04 2.558403e-02 8.513325e-03 1.301089e-03 0 4 TRUE TRUE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190480 0.6513850 U 0.4686274 0.6162291 13773 129 183057 183058 1 21 Same + + 0.000000 0 0.000000 -0.19699536 1.430229 3.527537 1.2028116 477 Permeases of the major facilitator superfamily GEPR transport protein, conjectural 1.432779 3.044840 1.0717709 549 Carbamate kinase E carbamate kinase 4.435849e-03 4 6.502123e-06 3.939408e-04 2.508617e-02 8.857298e-03 1.089051e-03 4 23 TRUE TRUE 124 TRUE 0.4469764 0.2720690 0.5480306 0.4469764 0.7323301 0.5403680 0.5189635 0.6517684 U 0.4686274 0.5483499 13773 129 183058 183059 1 -3 Convergent + - 0.000000 0 0.000000 -7.48438896 1.432779 3.044840 1.0717709 549 Carbamate kinase E carbamate kinase 1.444085 3.059771 1.0708534 124 Histidyl-tRNA synthetase J histidyl-tRNA synthetase 1.547415e-02 23 1.278253e-04 1.360285e-04 2.158392e-02 -2.123325e-03 1.121681e-02 0 23 71 TRUE TRUE 125 FALSE 0.4469764 0.1789388 0.5480306 0.4469764 0.7771174 0.6410036 0.5199440 0.6422810 N 0.5492530 0.5276550 13773 129 183059 183060 1 -3 Same - - 0.000000 0 0.000000 -0.63258440 1.444085 3.059771 1.0708534 124 Histidyl-tRNA synthetase J histidyl-tRNA synthetase 1.458357 3.193408 1.0838417 1748 Saccharopine dehydrogenase and related proteins E saccharopine dehydrogenase, conjectural 3.502625e-03 6 2.037016e-04 -5.089593e-05 2.013015e-02 4.267264e-03 1.742481e-02 0 71 6 FALSE TRUE 124 TRUE 0.4469764 0.2291582 0.5480306 0.4469764 0.7537284 0.5256684 0.5195959 0.6390912 N 0.5492530 0.5435688 13773 129 183060 183061 1 29 Same - - 0.000000 0 0.000000 -0.25386871 1.458357 3.193408 1.0838417 1748 Saccharopine dehydrogenase and related proteins E saccharopine dehydrogenase, conjectural 1.413774 3.226923 1.1297677 463 Glycosyltransferases involved in cell wall biogenesis M dolichol-phosphate mannosyltransferase 8.364826e-02 4 1.987680e-03 -2.619970e-04 2.114504e-02 -4.328225e-02 1.860303e-01 0 6 4 FALSE TRUE 123 TRUE 0.4469764 0.2629185 0.5480306 0.4469764 0.7323301 0.9572128 0.5082162 0.5838164 N 0.5492530 0.5542192 13773 129 183061 183062 1 88 Divergent - + 0.000000 0 0.000000 0.00000000 1.413774 3.226923 1.1297677 463 Glycosyltransferases involved in cell wall biogenesis M dolichol-phosphate mannosyltransferase 1.425623 3.050311 1.0448407 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 1.404111e-04 9.694155e-04 3.016489e-02 4.537318e-02 1.121681e-02 0 4 0 FALSE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185692 0.6422810 N 0.5492530 0.6245624 13773 129 183062 183063 1 -14 Convergent + - 0.000000 0 0.000000 0.00000000 1.425623 3.050311 1.0448407 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.359101 2.964259 1.0505633 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 0.000000e+00 0 4.425208e-03 2.378297e-03 6.848990e-02 1.215490e-01 3.173243e-01 0 0 20 TRUE TRUE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5223089 0.5362123 N 0.5492530 0.6245624 13773 129 183063 183064 1 -3 Same - - 25.441114 0 41.338438 41.33843843 1.359101 2.964259 1.0505633 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 1.454800 3.167643 1.1210495 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 2.249681e-01 19 9.158329e-03 -3.144880e-04 -4.540788e-03 -9.410246e-02 7.375158e-01 C 20 19 FALSE TRUE 122 TRUE 2.2181059 2.0238116 0.5480306 2.2546018 0.7779521 1.1530726 0.4940106 0.4611592 Y 1.4497162 0.9332016 13773 129 183064 183065 1 98 Divergent - + 0.000000 0 0.000000 0.00000000 1.454800 3.167643 1.1210495 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 1.467931 3.300798 1.0829511 - - - hypothetical protein 0.000000e+00 0 1.724163e-04 5.635499e-05 2.206171e-02 3.186224e-02 1.396859e-02 19 0 FALSE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174130 0.6410384 U 0.4686274 0.6162291 13773 129 183065 183066 1 27 Convergent + - 0.000000 0 0.000000 0.00000000 1.467931 3.300798 1.0829511 - - - hypothetical protein 1.583361 3.479786 1.1043228 105 Nucleoside diphosphate kinase F nucleoside diphosphate kinase (ndk) 0.000000e+00 0 1.332412e-02 2.182532e-03 8.978911e-02 2.067253e-01 3.474030e-01 0 60 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5522851 0.5254647 U 0.4686274 0.6162291 13773 129 183066 183067 1 -12 Same - - 0.000000 0 0.000000 0.00000000 1.583361 3.479786 1.1043228 105 Nucleoside diphosphate kinase F nucleoside diphosphate kinase (ndk) 1.535758 3.300807 1.1270602 - - - paREP2a 0.000000e+00 0 2.266110e-03 1.113348e-02 1.247610e-01 5.835815e-01 1.929605e-02 60 0 FALSE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7148085 0.6380078 U 0.4686274 0.6162291 13773 129 183067 183068 1 7 Same - - 0.000000 0 0.000000 0.00000000 1.535758 3.300807 1.1270602 - - - paREP2a 1.433623 2.869128 0.9411958 - - - paREP2a 0.000000e+00 0 1.043155e-02 -1.499181e-03 -1.406395e-02 -4.925642e-02 5.901730e-01 0 0 FALSE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5068411 0.4780286 U 0.4686274 0.6162291 13773 129 183068 183069 1 225 Divergent - + 0.000000 0 0.000000 0.00000000 1.433623 2.869128 0.9411958 - - - paREP2a 1.456494 3.103662 1.1009442 - - - paREP2b 0.000000e+00 0 5.230813e-04 -9.064139e-05 1.894203e-02 -1.029562e-02 4.683919e-02 0 0 FALSE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184930 0.6252488 U 0.4686274 0.6162291 13773 129 183069 183070 1 204 Convergent + - 0.000000 0 0.000000 0.00000000 1.456494 3.103662 1.1009442 - - - paREP2b 1.434990 3.680323 1.2489176 1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N) C NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 4.624125e-04 -8.366769e-05 2.037663e-02 -8.952715e-03 4.293769e-02 0 0 TRUE TRUE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5189215 0.6268270 U 0.4686274 0.6162291 13773 129 183070 183071 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.434990 3.680323 1.2489176 1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N) C NADH-ubiquinone oxidoreductase subunit 1.430693 3.391675 1.1771712 1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit CP NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 1.846116e-05 3.395376e-04 2.511250e-02 6.643857e-03 2.191648e-03 0 23 FALSE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193109 0.6499017 U 0.4686274 0.6162291 13773 129 183071 183072 1 36 Same - - 0.000000 0 0.000000 0.00000000 1.430693 3.391675 1.1771712 1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit CP NADH-ubiquinone oxidoreductase subunit 1.376700 3.144082 1.1274206 - - - paREP2a 0.000000e+00 0 2.915238e-03 1.546113e-03 5.189505e-02 6.660467e-02 2.573440e-01 23 0 FALSE TRUE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182164 0.5597228 U 0.4686274 0.6162291 13773 129 183072 183073 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.376700 3.144082 1.1274206 - - - paREP2a 1.357659 2.868411 0.9714042 - - - paREP2a 0.000000e+00 0 3.625719e-04 7.001234e-03 1.107424e-01 4.515891e-01 1.396859e-02 0 0 FALSE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6567275 0.6410384 U 0.4686274 0.6162291 13773 129 183073 183074 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.357659 2.868411 0.9714042 - - - paREP2a 1.504300 3.147225 1.0096176 - - - paREP2a 0.000000e+00 0 2.150369e-02 -4.959222e-03 -5.245060e-02 -3.924658e-01 1.609374e+00 0 0 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4210069 0.4143998 U 0.4686274 0.6162291 13773 129 183074 183075 1 10 Divergent - + 0.000000 0 0.000000 0.00000000 1.504300 3.147225 1.0096176 - - - paREP2a 1.442461 3.027432 1.0387628 - - - paREP2b 0.000000e+00 0 3.824137e-03 -4.725786e-04 8.306197e-03 6.568466e-03 2.731526e-01 0 0 FALSE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193302 0.5527293 U 0.4686274 0.6162291 13773 129 183075 183076 1 43 Convergent + - 0.000000 0 0.000000 0.00000000 1.442461 3.027432 1.0387628 - - - paREP2b 1.359956 3.201628 1.1015924 651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit CP NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 6.807021e-03 8.167302e-04 5.131658e-02 -8.877324e-03 5.405579e-01 0 7 TRUE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5189974 0.4849703 U 0.4686274 0.6162291 13773 129 183076 183077 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.359956 3.201628 1.1015924 651 Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit CP NADH-ubiquinone oxidoreductase subunit 1.472374 3.691760 1.1604614 - - - NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 1.263787e-02 -1.918474e-03 -2.180777e-02 -2.063978e-01 1.016955e+00 7 0 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4626487 0.4380418 U 0.4686274 0.6162291 13773 129 183077 183078 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.472374 3.691760 1.1604614 - - - NADH-ubiquinone oxidoreductase subunit 1.422490 3.490697 1.1242073 - - - NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 2.488435e-03 -6.064217e-04 1.465073e-02 -5.652933e-02 2.337719e-01 0 0 FALSE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5049120 0.5690733 U 0.4686274 0.6162291 13773 129 183078 183079 1 101 Same - - 0.000000 0 0.000000 0.00000000 1.422490 3.490697 1.1242073 - - - NADH-ubiquinone oxidoreductase subunit 1.411342 2.894303 0.9999562 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C NADH-ubiquinone oxidoreductase subunit 0.000000e+00 0 1.242758e-04 1.157578e-03 3.622451e-02 5.972050e-02 1.073442e-02 0 16 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185614 0.6423615 U 0.4686274 0.6162291 13773 129 183079 183080 1 -3 Same - - 18.405656 0 41.934534 41.80937081 1.411342 2.894303 0.9999562 1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) C NADH-ubiquinone oxidoreductase subunit 1.449389 3.556734 1.1987109 1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H) C NADH-ubiquinone oxidoreductase subunit 1.158520e-01 16 1.447579e-03 8.024772e-05 1.761264e-02 -2.291601e-02 1.425743e-01 C 16 38 FALSE TRUE 112 TRUE 2.4586389 2.0303387 0.5480306 2.2389773 0.7783446 1.0505506 0.5144025 0.5949759 Y 1.4497162 0.9318485 13773 129 183080 183081 1 10 Same - - 52.004183 0 81.277326 80.28149061 1.449389 3.556734 1.1987109 1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H) C NADH-ubiquinone oxidoreductase subunit 1.420219 3.090201 1.0880497 649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 C NADH-ubiquinone oxidoreductase subunit 3.234946e-01 37 8.509079e-04 6.246183e-05 2.392575e-02 -1.661848e-02 8.685076e-02 C 38 37 FALSE TRUE 111 TRUE 2.0508598 2.0632116 0.5480306 2.0983145 0.7740003 1.2379091 0.5164671 0.6122969 Y 1.4497162 0.9374898 13773 129 183081 183082 1 65 Same - - 0.000000 0 0.000000 0.00000000 1.420219 3.090201 1.0880497 649 NADH:ubiquinone oxidoreductase 49 kD subunit 7 C NADH-ubiquinone oxidoreductase subunit 1.936089 4.390122 1.2374460 - - - paREP2a 0.000000e+00 0 2.661218e-01 -1.510990e-02 4.382078e-01 -2.182224e-01 1.479686e+00 37 0 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4596811 0.4174963 U 0.4686274 0.6162291 13773 129 183082 183083 1 92 Divergent - + 0.000000 0 0.000000 0.00000000 1.936089 4.390122 1.2374460 - - - paREP2a 1.475139 3.319046 1.1356706 - - - conserved within P. aerophilum 0.000000e+00 0 2.124745e-01 1.150977e-02 -4.398621e-01 3.177625e-01 4.613151e-01 0 0 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5987183 0.5017230 U 0.4686274 0.6162291 13773 129 183083 183084 1 64 Same + + 0.000000 0 0.000000 0.00000000 1.475139 3.319046 1.1356706 - - - conserved within P. aerophilum 1.392875 3.147388 0.9880515 - - - paREP10, authentic frameshift 0.000000e+00 0 6.767322e-03 -1.389575e-03 1.175438e-02 -1.510594e-01 6.285094e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4762668 0.4734023 U 0.4686274 0.6162291 13773 129 183084 183085 1 155 Same + + 0.000000 0 0.000000 0.00000000 1.392875 3.147388 0.9880515 - - - paREP10, authentic frameshift 1.441403 3.139725 1.0359430 302 GTP cyclohydrolase I H GTP cyclohydrolase I 0.000000e+00 0 2.354901e-03 5.845906e-04 1.913034e-02 -3.639985e-04 2.256797e-01 0 37 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199812 0.5724137 U 0.4686274 0.6162291 13773 129 183085 183086 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.441403 3.139725 1.0359430 302 GTP cyclohydrolase I H GTP cyclohydrolase I 1.433682 3.267609 1.1084531 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR 3-oxoacyl-(acyl carrier protein) reductase 0.000000e+00 0 5.960422e-05 1.769277e-04 2.334947e-02 -5.359849e-05 4.985249e-03 37 0 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199683 0.6463622 U 0.4686274 0.6162291 13773 129 183086 183087 1 -52 Convergent + - 0.000000 0 0.000000 0.00000000 1.433682 3.267609 1.1084531 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR 3-oxoacyl-(acyl carrier protein) reductase 1.502762 3.409973 1.1472071 - - - hypothetical protein 0.000000e+00 0 4.771993e-03 -9.097698e-04 1.600511e-02 -3.650057e-02 3.510312e-01 0 0 TRUE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5103561 0.5247424 U 0.4686274 0.6162291 13773 129 183087 183088 1 205 Divergent - + 0.000000 0 0.000000 0.00000000 1.502762 3.409973 1.1472071 - - - hypothetical protein 1.411838 3.109882 1.0281633 1522 Transcriptional regulators K transcriptional regulatory protein, conjectural 0.000000e+00 0 8.267240e-03 -2.031917e-03 -5.747953e-03 -1.544255e-01 6.693073e-01 0 1 FALSE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4756276 0.4688853 U 0.4686274 0.6162291 13773 129 183088 183089 1 24 Convergent + - 0.000000 0 0.000000 0.00000000 1.411838 3.109882 1.0281633 1522 Transcriptional regulators K transcriptional regulatory protein, conjectural 1.486562 3.209049 1.0785602 - - - hypothetical protein 0.000000e+00 0 5.583780e-03 -1.391137e-03 3.639896e-03 -1.244928e-01 5.138128e-01 1 0 TRUE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4836706 0.4908988 U 0.4686274 0.6162291 13773 129 183089 183090 1 72 Divergent - + 0.000000 0 0.000000 0.00000000 1.486562 3.209049 1.0785602 - - - hypothetical protein 1.466193 3.053890 1.0747932 308 Aminopeptidase N E aminopeptidase 0.000000e+00 0 4.149258e-04 5.205022e-04 2.423868e-02 9.668402e-02 3.681215e-02 0 3 FALSE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181692 0.6292170 U 0.4686274 0.6162291 13773 129 183090 183091 1 6 Same + + 0.000000 0 0.000000 -0.11352903 1.466193 3.053890 1.0747932 308 Aminopeptidase N E aminopeptidase 1.487560 3.237043 1.0389386 35 Uracil phosphoribosyltransferase F uracil phosphoribosyltransferase 1.232289e-02 3 4.565696e-04 5.352689e-04 2.976183e-02 9.826900e-02 3.951033e-02 0 3 55 TRUE TRUE 113 TRUE 0.4469764 0.2958778 0.5480306 0.4469764 0.7136133 0.6176927 0.5183863 0.6282866 N 0.5492530 0.5645692 13773 129 183091 183092 1 -35 Convergent + - 0.000000 0 0.000000 0.00000000 1.487560 3.237043 1.0389386 35 Uracil phosphoribosyltransferase F uracil phosphoribosyltransferase 1.495062 3.418521 1.1678290 - - - hypothetical protein 0.000000e+00 0 5.627639e-05 1.579392e-03 4.072532e-02 2.031112e-01 2.120380e-03 55 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5504627 0.6501030 U 0.4686274 0.6162291 13773 129 183092 183093 1 81 Same - - 0.000000 0 0.000000 0.00000000 1.495062 3.418521 1.1678290 - - - hypothetical protein 1.459086 3.190362 1.0471715 - - - paREP2b 0.000000e+00 0 1.294264e-03 3.359538e-04 1.997325e-02 8.044368e-02 9.283082e-02 0 0 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177562 0.6099430 U 0.4686274 0.6162291 13773 129 183093 183094 1 7 Same - - 0.000000 0 0.000000 0.00000000 1.459086 3.190362 1.0471715 - - - paREP2b 1.334838 2.781674 1.0233875 - - - paREP2b 0.000000e+00 0 1.543748e-02 -8.966746e-04 4.460232e-02 -1.452672e-01 1.052868e+00 0 0 FALSE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4787871 0.4357796 U 0.4686274 0.6162291 13773 129 183094 183095 1 -24 Same - - 0.000000 0 0.000000 0.00000000 1.334838 2.781674 1.0233875 - - - paREP2b 1.440615 3.346248 1.1144424 - - - paREP2b 0.000000e+00 0 1.118879e-02 1.256157e-03 1.220901e-03 3.943907e-03 7.257000e-01 0 0 FALSE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196275 0.4622435 U 0.4686274 0.6162291 13773 129 183095 183096 1 54 Same - - 0.000000 0 0.000000 0.00000000 1.440615 3.346248 1.1144424 - - - paREP2b 1.490294 3.573741 1.1327745 - - - paREP2b 0.000000e+00 0 2.467989e-03 -4.192573e-04 1.938374e-02 -2.049701e-03 2.022583e-01 0 0 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199505 0.5792906 U 0.4686274 0.6162291 13773 129 183096 183097 1 22 Same - - 0.000000 0 0.000000 0.00000000 1.490294 3.573741 1.1327745 - - - paREP2b 1.412634 2.889943 1.1134940 - - - paREP2b 0.000000e+00 0 6.031089e-03 -1.507767e-03 3.080293e-03 -1.287895e-01 5.394299e-01 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4823466 0.4851972 U 0.4686274 0.6162291 13773 129 183097 183098 1 46 Divergent - + 0.000000 0 0.000000 0.00000000 1.412634 2.889943 1.1134940 - - - paREP2b 1.640972 3.672313 1.2105126 - - - paREP2a 0.000000e+00 0 5.213807e-02 -7.347825e-03 2.228035e-02 -2.666831e-01 1.466646e+00 0 0 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4481710 0.4179446 U 0.4686274 0.6162291 13773 129 183098 183099 1 93 Same + + 0.000000 0 0.000000 0.00000000 1.640972 3.672313 1.2105126 - - - paREP2a 1.567396 3.315651 1.0246091 - - - paREP2a 0.000000e+00 0 5.413449e-03 2.199170e-02 2.207737e-01 7.342628e-01 1.564899e-02 0 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7635163 0.6400352 U 0.4686274 0.6162291 13773 129 183099 183100 1 182 Convergent + - 0.000000 0 0.000000 0.00000000 1.567396 3.315651 1.0246091 - - - paREP2a 1.447676 3.159342 1.0709606 166 Glucose-6-phosphate isomerase G glucose-6-phosphate isomerase, conjectural 0.000000e+00 0 1.433283e-02 -4.311808e-04 -1.844201e-02 4.768734e-02 5.428172e-01 0 4 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187117 0.4845925 U 0.4686274 0.6162291 13773 129 183100 183101 1 17 Divergent - + 0.000000 0 0.000000 0.00000000 1.447676 3.159342 1.0709606 166 Glucose-6-phosphate isomerase G glucose-6-phosphate isomerase, conjectural 1.514859 3.326402 1.1465614 1061 DNA or RNA helicases of superfamily II KL helicase, possible DNA repair rad25 0.000000e+00 0 4.513577e-03 -2.359028e-04 2.817339e-02 3.551283e-02 2.844990e-01 4 0 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176437 0.5488286 U 0.4686274 0.6162291 13773 129 183101 183102 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.514859 3.326402 1.1465614 1061 DNA or RNA helicases of superfamily II KL helicase, possible DNA repair rad25 1.410860 3.031554 1.0303875 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 1.081585e-02 -2.572481e-03 -1.539727e-02 -1.830277e-01 8.131804e-01 0 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4692822 0.4538896 U 0.4686274 0.6162291 13773 129 183102 183103 1 117 Divergent - + 0.000000 0 0.000000 0.00000000 1.410860 3.031554 1.0303875 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.645711 3.556183 1.0468309 - - - hypothetical protein 0.000000e+00 0 5.515525e-02 -7.876330e-03 2.036418e-02 -2.869722e-01 1.534328e+00 0 0 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4434757 0.4161356 U 0.4686274 0.6162291 13773 129 183103 183104 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.645711 3.556183 1.0468309 - - - hypothetical protein 1.478024 3.038258 0.9557459 - - - hypothetical protein 0.000000e+00 0 2.811914e-02 5.174859e-03 -1.284637e-02 3.255207e-01 3.366315e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6020978 0.5289643 U 0.4686274 0.6162291 13773 129 183104 183105 1 334 Convergent + - 0.000000 0 0.000000 0.00000000 1.478024 3.038258 0.9557459 - - - hypothetical protein 1.368074 3.154333 1.0325238 - - - hypothetical protein 0.000000e+00 0 1.208902e-02 -2.218861e-03 1.062266e-02 -2.371574e-01 1.056020e+00 0 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4542561 0.4355435 U 0.4686274 0.6162291 13773 129 183105 183106 1 190 Divergent - + 0.000000 0 0.000000 0.00000000 1.368074 3.154333 1.0325238 - - - hypothetical protein 1.453609 3.067618 1.0749943 60 Isoleucyl-tRNA synthetase J isoleucyl-tRNA synthetase 0.000000e+00 0 7.316346e-03 -1.846662e-04 9.614672e-04 -7.957255e-02 6.321653e-01 0 71 FALSE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4980461 0.4727649 U 0.4686274 0.6162291 13773 129 183106 183107 1 7 Convergent + - 0.000000 0 0.000000 0.00000000 1.453609 3.067618 1.0749943 60 Isoleucyl-tRNA synthetase J isoleucyl-tRNA synthetase 1.572817 3.265605 1.0591749 - - - paREP2a 0.000000e+00 0 1.421039e-02 2.691196e-04 6.131364e-02 9.525276e-02 4.813357e-01 71 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180158 0.4963031 U 0.4686274 0.6162291 13773 129 183107 183108 1 110 Divergent - + 0.000000 0 0.000000 0.00000000 1.572817 3.265605 1.0591749 - - - paREP2a 1.430185 3.019390 1.0217671 - - - paREP2b 0.000000e+00 0 2.034383e-02 -2.575165e-03 -4.567144e-02 -9.151736e-02 8.538157e-01 0 0 FALSE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4949439 0.4498973 U 0.4686274 0.6162291 13773 129 183108 183109 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.430185 3.019390 1.0217671 - - - paREP2b 1.407460 3.041852 1.0418444 - - - paREP2b 0.000000e+00 0 5.164010e-04 9.317255e-04 3.539089e-02 3.766325e-02 4.885355e-02 0 0 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178788 0.6242586 U 0.4686274 0.6162291 13773 129 183109 183110 1 366 Same + + 0.000000 0 0.000000 0.00000000 1.407460 3.041852 1.0418444 - - - paREP2b 1.410305 3.281698 1.1471241 4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase O hypothetical protein 0.000000e+00 0 8.093535e-06 1.805085e-03 4.122900e-02 1.042785e-01 4.617716e-04 0 3 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191924 0.6534780 U 0.4686274 0.6162291 13773 129 183110 183111 1 -16 Convergent + - 0.000000 0 0.000000 -0.13150953 1.410305 3.281698 1.1471241 4346 Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase O hypothetical protein 1.489336 3.385011 1.0827097 1645 Uncharacterized Zn-finger containing protein R conserved hypothetical protein 7.283192e-02 3 6.245867e-03 -1.558995e-03 1.878392e-03 -1.371203e-01 5.645164e-01 3 3 TRUE TRUE 113 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7136133 0.9306064 0.4802728 0.4819602 U 0.4686274 0.5537552 13773 129 183111 183112 1 20 Divergent - + 0.000000 0 0.000000 -0.06317890 1.489336 3.385011 1.0827097 1645 Uncharacterized Zn-finger containing protein R conserved hypothetical protein 1.504212 3.367551 1.0832202 2112 Predicted Ser/Thr protein kinase T conserved hypothetical protein 4.578021e-02 1 2.213055e-04 2.004139e-03 4.759953e-02 2.341488e-01 8.910896e-03 3 1 FALSE TRUE 112 FALSE 0.4469764 0.3037120 0.5480306 0.4469764 0.6329203 0.8313457 0.5632668 0.6435760 U 0.4686274 0.5583141 13773 129 183112 183113 1 83 Convergent + - 0.000000 0 0.000000 -0.06317890 1.504212 3.367551 1.0832202 2112 Predicted Ser/Thr protein kinase T conserved hypothetical protein 1.459045 3.221731 1.0523798 2016 Predicted RNA-binding protein (contains PUA domain) J conserved protein with predicted RNA binding PUA domain 3.279005e-02 1 2.040054e-03 4.042032e-04 1.852749e-02 8.964789e-02 1.334520e-01 0 1 7 TRUE TRUE 113 FALSE 0.4469764 0.3037120 0.5480306 0.4469764 0.6329203 0.7581838 0.5177916 0.5974546 N 0.5492530 0.5670214 13773 129 183113 183114 1 134 Divergent - + 0.000000 0 0.000000 0.00000000 1.459045 3.221731 1.0523798 2016 Predicted RNA-binding protein (contains PUA domain) J conserved protein with predicted RNA binding PUA domain 1.410174 3.137232 1.0713799 1395 Predicted transcriptional regulator K hypothetical protein 0.000000e+00 0 2.388439e-03 -3.154309e-04 2.121553e-02 -5.275682e-02 2.322900e-01 0 7 0 FALSE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5059956 0.5700736 N 0.5492530 0.6245624 13773 129 183114 183115 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.410174 3.137232 1.0713799 1395 Predicted transcriptional regulator K hypothetical protein 1.503243 3.227130 1.1168623 1867 N2,N2-dimethylguanosine tRNA methyltransferase J N2,N2-dimethylguonasine tRNA methyltransferase 0.000000e+00 0 8.661863e-03 -2.137212e-03 -1.738582e-03 -1.650156e-01 7.049297e-01 0 0 13 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4736865 0.4643453 N 0.5492530 0.6245624 13773 129 183115 183116 1 -3 Same + + 0.000000 0 0.000000 -1.00117141 1.503243 3.227130 1.1168623 1867 N2,N2-dimethylguanosine tRNA methyltransferase J N2,N2-dimethylguonasine tRNA methyltransferase 1.522231 3.456674 1.1157389 237 Dephospho-CoA kinase H adenylate kinase, conjectural 2.704009e-01 13 3.605498e-04 3.672959e-03 6.959905e-02 3.328555e-01 1.154429e-02 0 13 13 TRUE TRUE 114 TRUE 0.4469764 0.2105111 0.5480306 0.4469764 0.7781369 1.2002299 0.6047339 0.6421803 N 0.5492530 0.5376684 13773 129 183116 183117 1 62 Same + + 0.000000 0 0.000000 0.00000000 1.522231 3.456674 1.1157389 237 Dephospho-CoA kinase H adenylate kinase, conjectural 1.433689 3.189965 1.1058927 - - - paREP2b 0.000000e+00 0 7.839618e-03 -1.254080e-03 -5.872824e-03 -4.373283e-02 4.931208e-01 13 0 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5079782 0.4934901 U 0.4686274 0.6162291 13773 129 183117 183118 1 40 Same + + 0.000000 0 0.000000 0.00000000 1.433689 3.189965 1.1058927 - - - paREP2b 1.552638 3.315227 1.0822815 1931 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.414884e-02 -1.792395e-03 2.501619e-02 -5.184329e-02 6.718212e-01 0 9 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5062086 0.4681425 U 0.4686274 0.6162291 13773 129 183118 183119 1 165 Convergent + - 0.000000 0 0.000000 0.00000000 1.552638 3.315227 1.0822815 1931 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.511983 3.330909 1.0984484 1041 Predicted DNA modification methylase L hypothetical protein 0.000000e+00 0 1.652873e-03 6.134453e-03 7.575472e-02 4.314514e-01 3.088746e-02 9 0 TRUE TRUE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6479112 0.6324772 U 0.4686274 0.6162291 13773 129 183119 183120 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.511983 3.330909 1.0984484 1041 Predicted DNA modification methylase L hypothetical protein 1.495022 3.366815 1.1306385 2237 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 2.876621e-04 2.643496e-03 4.715730e-02 2.721938e-01 1.026264e-02 0 1 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5813830 0.6426621 U 0.4686274 0.6162291 13773 129 183120 183121 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.495022 3.366815 1.1306385 2237 Predicted membrane protein S conserved hypothetical protein 1.416246 3.056409 0.9947379 1340 Uncharacterized archaeal coiled-coil protein S conserved hypothetical protein 3.728161e-04 1 6.205739e-03 -1.533448e-03 1.111308e-03 -1.191983e-01 5.259867e-01 1 2 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.4854555 0.4884610 U 0.4686274 0.6162291 13773 129 183121 183122 1 105 Divergent - + 0.000000 0 0.000000 -0.23662690 1.416246 3.056409 0.9947379 1340 Uncharacterized archaeal coiled-coil protein S conserved hypothetical protein 1.556902 3.530238 1.1403943 1709 Predicted transcriptional regulator K conserved hypothetical protein 5.377067e-02 2 1.978420e-02 -3.708351e-03 2.511747e-03 -1.924174e-01 1.032493e+00 2 11 FALSE TRUE 114 FALSE 0.4469764 0.2691051 0.5480306 0.4469764 0.6838149 0.8640648 0.4667950 0.4369659 U 0.4686274 0.5474145 13773 129 183122 183123 1 1 Convergent + - 0.000000 0 0.000000 0.00000000 1.556902 3.530238 1.1403943 1709 Predicted transcriptional regulator K conserved hypothetical protein 1.458279 3.278367 1.1008043 4352 Ribosomal protein L13E J ribosomal protein L13 0.000000e+00 0 9.726539e-03 7.265247e-04 1.082580e-03 1.208475e-01 3.675914e-01 0 11 0 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5222160 0.5196393 N 0.5492530 0.6245624 13773 129 183123 183124 1 76 Divergent - + 0.000000 0 0.000000 0.00000000 1.458279 3.278367 1.1008043 4352 Ribosomal protein L13E J ribosomal protein L13 1.414442 3.609273 1.1025289 - - - hypothetical protein 0.000000e+00 0 1.921680e-03 -2.544412e-04 2.110968e-02 -4.210250e-02 1.801198e-01 0 0 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5085545 0.5850474 U 0.4686274 0.6162291 13773 129 183124 183125 1 2 Convergent + - 0.000000 0 0.000000 0.00000000 1.414442 3.609273 1.1025289 - - - hypothetical protein 1.598972 3.432873 0.9186114 - - - hypothetical protein 0.000000e+00 0 3.405151e-02 -5.453218e-03 8.819455e-03 -2.299287e-01 1.276224e+00 0 0 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4570843 0.4252479 U 0.4686274 0.6162291 13773 129 183125 183126 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.598972 3.432873 0.9186114 - - - hypothetical protein 1.529494 3.181646 1.0569364 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR hypothetical protein 0.000000e+00 0 4.827219e-03 1.152614e-02 1.156853e-01 5.824418e-01 3.564359e-02 0 0 FALSE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7144012 0.6297015 U 0.4686274 0.6162291 13773 129 183126 183127 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.529494 3.181646 1.0569364 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR hypothetical protein 1.483815 3.283800 1.1043371 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB (TFIIB) 0.000000e+00 0 2.086577e-03 2.532213e-03 3.752405e-02 2.681821e-01 7.675834e-02 0 11 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5776273 0.6159494 U 0.4686274 0.6162291 13773 129 183127 183128 1 68 Same - - 0.000000 0 0.000000 0.00000000 1.483815 3.283800 1.1043371 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB (TFIIB) 1.442574 3.118717 1.0709417 470 ATPase involved in DNA replication L replication factor C small subunit 0.000000e+00 0 1.700858e-03 -2.859402e-04 1.492239e-02 6.101982e-03 1.460730e-01 0 11 0 FALSE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193682 0.5939828 N 0.5492530 0.6245624 13773 129 183128 183129 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.442574 3.118717 1.0709417 470 ATPase involved in DNA replication L replication factor C small subunit 1.529081 3.461236 1.1373277 - - - hypothetical protein 0.000000e+00 0 7.483496e-03 -6.851514e-04 2.785617e-02 1.031918e-02 4.315774e-01 0 0 FALSE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5188779 0.5072321 U 0.4686274 0.6162291 13773 129 183129 183130 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.529081 3.461236 1.1373277 - - - hypothetical protein 1.472715 3.254302 1.0936074 1163 Predicted GTPase R GTP-binding protein 0.000000e+00 0 3.177125e-03 1.656457e-03 2.593299e-02 1.960645e-01 1.449020e-01 0 11 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5483632 0.5942416 U 0.4686274 0.6162291 13773 129 183130 183131 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.472715 3.254302 1.0936074 1163 Predicted GTPase R GTP-binding protein 1.582085 3.497829 1.0664632 1024 Enoyl-CoA hydratase/carnithine racemase I enoyl-CoA hydratase, probable 0.000000e+00 0 1.196192e-02 2.786617e-03 9.554122e-02 2.423948e-01 2.910863e-01 11 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5660237 0.5467439 U 0.4686274 0.6162291 13773 129 183131 183132 1 26 Divergent - + 0.000000 0 0.000000 0.00000000 1.582085 3.497829 1.0664632 1024 Enoyl-CoA hydratase/carnithine racemase I enoyl-CoA hydratase, probable 1.502175 3.086425 1.0720690 538 Isocitrate dehydrogenases C isocitrate dehydrogenase 0.000000e+00 0 6.385741e-03 6.636781e-03 6.150947e-02 4.318454e-01 9.708748e-02 0 0 31 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6482321 0.6079718 N 0.5492530 0.6245624 13773 129 183132 183133 1 3 Convergent + - 0.000000 0 0.000000 -1.81914412 1.502175 3.086425 1.0720690 538 Isocitrate dehydrogenases C isocitrate dehydrogenase 1.404368 3.036356 1.0346258 454 Histone acetyltransferase HPA2 and related acetyltransferases KR N-acyltransferase 1.359634e-01 14 9.566029e-03 -2.387978e-03 -8.116438e-03 -1.929946e-01 7.939179e-01 31 14 TRUE TRUE 109 FALSE 0.4469764 0.1985579 0.5480306 0.4469764 0.7782928 1.0718732 0.4666550 0.4559908 U 0.4686274 0.5250650 13773 129 183133 183134 1 144 Same - - 0.000000 0 0.000000 -0.40136208 1.404368 3.036356 1.0346258 454 Histone acetyltransferase HPA2 and related acetyltransferases KR N-acyltransferase 1.513294 3.226635 1.0262213 1499 NMD protein affecting ribosome stability and mRNA decay J conserved hypothetical protein 3.889664e-02 7 1.186489e-02 -2.910889e-03 -9.181921e-03 -2.160856e-01 9.085616e-01 14 7 FALSE TRUE 108 TRUE 0.4469764 0.2421805 0.5480306 0.4469764 0.7596462 0.7986660 0.4601321 0.4456325 U 0.4686274 0.5389023 13773 129 183134 183135 1 54 Same - - 0.000000 0 0.000000 0.00000000 1.513294 3.226635 1.0262213 1499 NMD protein affecting ribosome stability and mRNA decay J conserved hypothetical protein 1.439142 3.086956 1.0725699 - - - paREP2b 0.000000e+00 0 5.498632e-03 -7.583638e-04 2.520914e-03 -1.160790e-02 3.620289e-01 7 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181422 0.5204865 U 0.4686274 0.6162291 13773 129 183135 183136 1 128 Same - - 0.000000 0 0.000000 0.00000000 1.439142 3.086956 1.0725699 - - - paREP2b 1.445380 3.125551 1.0271900 - - - paREP2b 0.000000e+00 0 3.891381e-05 7.366607e-05 2.130968e-02 -7.350650e-04 3.225333e-03 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199871 0.6482245 U 0.4686274 0.6162291 13773 129 183136 183137 1 101 Divergent - + 0.000000 0 0.000000 0.00000000 1.445380 3.125551 1.0271900 - - - paREP2b 1.392735 2.845533 0.9146989 - - - paREP2a 0.000000e+00 0 2.771428e-03 3.527076e-04 3.350748e-02 -1.752847e-02 2.628234e-01 0 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5160470 0.5561071 U 0.4686274 0.6162291 13773 129 183137 183138 1 86 Convergent + - 0.000000 0 0.000000 0.00000000 1.392735 2.845533 0.9146989 - - - paREP2a 1.457590 3.075389 1.0465259 270 Site-specific DNA methylase L C-5 cytosine-specific DNA methylase 0.000000e+00 0 4.206076e-03 -3.634939e-04 7.847483e-03 -7.157460e-02 3.921855e-01 0 16 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5010179 0.5135141 U 0.4686274 0.6162291 13773 129 183138 183139 1 249 Divergent - + 0.000000 0 0.000000 0.00000000 1.457590 3.075389 1.0465259 270 Site-specific DNA methylase L C-5 cytosine-specific DNA methylase 1.450697 3.158206 1.0254788 - - - hypothetical protein 0.000000e+00 0 4.751447e-05 -4.314120e-06 2.059096e-02 1.350682e-02 3.675914e-03 16 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183599 0.6475832 U 0.4686274 0.6162291 13773 129 183139 183140 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.450697 3.158206 1.0254788 - - - hypothetical protein 1.478875 3.057307 1.0179630 - - - hypothetical protein 0.000000e+00 0 7.940322e-04 -1.913253e-05 2.243080e-02 3.204424e-02 7.132958e-02 0 0 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174190 0.6173892 U 0.4686274 0.6162291 13773 129 183140 183141 1 53 Same - - 0.000000 0 0.000000 0.00000000 1.478875 3.057307 1.0179630 - - - hypothetical protein 1.558655 3.259558 1.1154707 - - - paREP2b 0.000000e+00 0 6.364765e-03 2.947814e-03 8.250365e-02 2.747040e-01 1.704809e-01 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5823368 0.5875676 U 0.4686274 0.6162291 13773 129 183141 183142 1 98 Divergent - + 0.000000 0 0.000000 0.00000000 1.558655 3.259558 1.1154707 - - - paREP2b 1.384430 2.960673 1.0565433 - - - paREP2a 0.000000e+00 0 3.035425e-02 -7.182559e-03 -8.107292e-02 -4.241667e-01 1.744508e+00 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4145867 0.4116236 U 0.4686274 0.6162291 13773 129 183142 183143 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.384430 2.960673 1.0565433 - - - paREP2a 1.519337 3.278958 1.0930615 - - - paREP2a 0.000000e+00 0 1.820001e-02 -4.549761e-03 -3.212305e-02 -3.400100e-01 1.364396e+00 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4300363 0.4215157 U 0.4686274 0.6162291 13773 129 183143 183144 1 14 Same + + 0.000000 0 0.000000 0.00000000 1.519337 3.278958 1.0930615 - - - paREP2a 1.450647 3.134390 1.0993020 72 Phenylalanyl-tRNA synthetase beta subunit J phenylalanyl-tRNA synthetase beta subunit 0.000000e+00 0 4.718432e-03 -5.070477e-05 8.422694e-03 5.493197e-02 2.787970e-01 0 14 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187498 0.5513597 U 0.4686274 0.6162291 13773 129 183144 183145 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.450647 3.134390 1.0993020 72 Phenylalanyl-tRNA synthetase beta subunit J phenylalanyl-tRNA synthetase beta subunit 1.377312 3.081946 1.0727553 - - - hypothetical protein 0.000000e+00 0 5.377916e-03 5.528383e-05 3.531931e-02 -5.404377e-02 4.845357e-01 14 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5054939 0.4953921 U 0.4686274 0.6162291 13773 129 183145 183146 1 202 Convergent + - 0.000000 0 0.000000 0.00000000 1.377312 3.081946 1.0727553 - - - hypothetical protein 1.479178 3.109151 1.0582535 - - - paREP2b 0.000000e+00 0 1.037670e-02 -2.058368e-03 -1.530537e-02 -2.175728e-01 9.321213e-01 0 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4598317 0.4446379 U 0.4686274 0.6162291 13773 129 183146 183147 1 146 Divergent - + 0.000000 0 0.000000 0.00000000 1.479178 3.109151 1.0582535 - - - paREP2b 1.545728 3.048947 1.1444039 - - - paREP2a 0.000000e+00 0 4.428870e-03 2.621158e-03 7.202388e-02 2.613074e-01 1.374059e-01 0 0 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5744620 0.5963968 U 0.4686274 0.6162291 13773 129 183147 183148 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.545728 3.048947 1.1444039 - - - paREP2a 1.446163 2.994457 0.9756445 - - - paREP2a 0.000000e+00 0 9.913305e-03 -4.933997e-04 -7.561279e-03 3.077496e-02 4.717992e-01 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173910 0.4985726 U 0.4686274 0.6162291 13773 129 183148 183149 1 126 Convergent + - 0.000000 0 0.000000 0.00000000 1.446163 2.994457 0.9756445 - - - paREP2a 1.620192 3.568533 1.0900456 - - - hypothetical protein 0.000000e+00 0 3.028621e-02 -8.828657e-04 8.270405e-02 3.783700e-02 7.296280e-01 0 0 TRUE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179306 0.4617333 U 0.4686274 0.6162291 13773 129 183149 183150 1 182 Same - - 0.000000 0 0.000000 0.00000000 1.620192 3.568533 1.0900456 - - - hypothetical protein 1.446741 3.067687 1.0365488 - - - hypothetical protein 0.000000e+00 0 3.008537e-02 -7.853035e-04 -6.074787e-02 4.678029e-02 7.126832e-01 0 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186507 0.4634542 U 0.4686274 0.6162291 13773 129 183150 183151 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.446741 3.067687 1.0365488 - - - hypothetical protein 1.422980 3.089350 1.0153016 2606 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 5.645782e-04 1.321864e-04 2.427845e-02 -1.009301e-02 6.031303e-02 0 9 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186303 0.6204913 U 0.4686274 0.6162291 13773 129 183151 183152 1 -3 Same - - 0.000000 0 0.000000 -0.13353139 1.422980 3.089350 1.0153016 2606 Uncharacterized conserved protein S conserved hypothetical protein 1.391851 2.901656 1.0248625 1371 Uncharacterized conserved protein S conserved hypothetical protein 1.445005e-03 9 9.689946e-04 1.691771e-03 4.747133e-02 9.380560e-02 8.505079e-02 9 12 FALSE TRUE 106 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.7702221 0.4814074 0.5179779 0.6126404 U 0.4686274 0.5517368 13773 129 183152 183153 1 46 Divergent - + 0.000000 0 0.000000 -0.13150953 1.391851 2.901656 1.0248625 1371 Uncharacterized conserved protein S conserved hypothetical protein 1.468918 3.246681 1.0862841 269 3-hexulose-6-phosphate synthase and related proteins G D-arabino 3-hexulose 6-phosphate formaldehyde lyase, conjectural 1.474155e-03 12 5.939250e-03 -1.043453e-03 3.141279e-04 -1.258186e-01 5.541848e-01 12 16 FALSE TRUE 105 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7776747 0.4825226 0.4833109 0.4831606 U 0.4686274 0.5537552 13773 129 183153 183154 1 12 Same + + 0.000000 0 0.000000 -0.13150953 1.468918 3.246681 1.0862841 269 3-hexulose-6-phosphate synthase and related proteins G D-arabino 3-hexulose 6-phosphate formaldehyde lyase, conjectural 1.472303 3.056318 1.0099632 2019 Archaeal adenylate kinase F adenylate kinase 6.289505e-03 5 1.146417e-05 3.664516e-04 2.535283e-02 7.385872e-02 6.414149e-04 0 16 5 TRUE TRUE 106 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.7448207 0.5613206 0.5179207 0.6527891 N 0.5492530 0.5624819 13773 129 183154 183155 1 206 Same + + 0.000000 0 0.000000 0.00000000 1.472303 3.056318 1.0099632 2019 Archaeal adenylate kinase F adenylate kinase 1.379918 3.014306 1.0443015 693 Putative intracellular protease/amidase R hypothetical protein 0.000000e+00 0 8.535130e-03 -1.494588e-03 1.512575e-02 -1.662914e-01 7.547516e-01 5 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4730313 0.4590531 U 0.4686274 0.6162291 13773 129 183155 183156 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.379918 3.014306 1.0443015 693 Putative intracellular protease/amidase R hypothetical protein 1.489607 3.385091 1.1652723 371 Glycerol dehydrogenase and related enzymes C glycerol dehydrogenase (gldA) 0.000000e+00 0 1.203179e-02 -2.731376e-03 -2.046339e-02 -2.577292e-01 1.051294e+00 0 22 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4510138 0.4359569 U 0.4686274 0.6162291 13773 129 183156 183157 1 546 Convergent + - 0.000000 0 0.000000 0.00000000 1.489607 3.385091 1.1652723 371 Glycerol dehydrogenase and related enzymes C glycerol dehydrogenase (gldA) 1.402809 2.960775 0.9790061 - - - hypothetical protein 0.000000e+00 0 7.533899e-03 -1.856594e-03 1.315544e-03 -1.723839e-01 6.921014e-01 22 0 TRUE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4723720 0.4654364 U 0.4686274 0.6162291 13773 129 183157 183158 1 42 Divergent - + 0.000000 0 0.000000 0.00000000 1.402809 2.960775 0.9790061 - - - hypothetical protein 1.440337 3.061804 1.0513678 281 Malic enzyme C malate oxidoreductase (mae) 0.000000e+00 0 1.408343e-03 5.371325e-04 2.133420e-02 2.698183e-03 1.472486e-01 0 34 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197433 0.5937974 U 0.4686274 0.6162291 13773 129 183158 183159 1 5 Convergent + - 0.000000 0 0.000000 -4.26782265 1.440337 3.061804 1.0513678 281 Malic enzyme C malate oxidoreductase (mae) 1.411544 3.000134 1.0372611 372 Citrate synthase C citrate synthase 4.401145e-02 34 8.290458e-04 4.405628e-04 2.961106e-02 2.067370e-03 8.549902e-02 C 34 50 TRUE TRUE 109 FALSE 0.4469764 0.1841525 0.5480306 0.4469764 0.7748967 0.8224763 0.5198060 0.6125263 Y 1.4497162 0.6254113 13773 129 183159 183160 1 128 Same - - 0.000000 0 0.000000 0.00000000 1.411544 3.000134 1.0372611 372 Citrate synthase C citrate synthase 1.419591 3.186390 1.0767873 - - - conserved hypothetical protein 5.342190e-03 1 6.476121e-05 1.267258e-03 3.409054e-02 6.638556e-02 6.008332e-03 50 1 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5472932 0.5182294 0.6454790 U 0.4686274 0.6162291 13773 129 183160 183161 1 39 Divergent - + 0.000000 0 0.000000 -0.12505431 1.419591 3.186390 1.0767873 - - - conserved hypothetical protein 1.435666 3.039781 1.0640687 1224 DNA helicase TIP49, TBP-interacting protein K TBP-interacting protein TIP49 3.505284e-02 1 2.583952e-04 5.001383e-04 2.464525e-02 1.225580e-02 2.773516e-02 1 6 FALSE TRUE 107 FALSE 0.4469764 0.2924948 0.5480306 0.4469764 0.6329203 0.7716100 0.5186177 0.6341446 U 0.4686274 0.5547868 13773 129 183161 183162 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.435666 3.039781 1.0640687 1224 DNA helicase TIP49, TBP-interacting protein K TBP-interacting protein TIP49 1.465010 3.401674 1.0887309 - - - hypothetical protein 0.000000e+00 0 8.610879e-04 -2.141596e-04 1.807648e-02 -1.217098e-02 7.591019e-02 6 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178065 0.6161199 U 0.4686274 0.6162291 13773 129 183162 183163 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.465010 3.401674 1.0887309 - - - hypothetical protein 1.529945 3.305609 1.0731580 - - - paREP2b 0.000000e+00 0 4.216568e-03 1.069685e-03 4.844388e-02 1.492636e-01 2.092202e-01 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5302680 0.5762640 U 0.4686274 0.6162291 13773 129 183163 183164 1 -22 Same - - 0.000000 0 0.000000 0.00000000 1.529945 3.305609 1.0731580 - - - paREP2b 1.425116 3.130633 1.0330164 - - - paREP2b 0.000000e+00 0 1.098920e-02 -2.064111e-03 -1.731306e-02 -1.159783e-01 7.204792e-01 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4863984 0.4629446 U 0.4686274 0.6162291 13773 129 183164 183165 1 72 Divergent - + 0.000000 0 0.000000 0.00000000 1.425116 3.130633 1.0330164 - - - paREP2b 1.515671 3.196324 1.0075708 - - - paREP2a 0.000000e+00 0 8.200250e-03 -1.689032e-03 9.728125e-03 -1.023183e-01 5.913527e-01 0 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4901164 0.4778085 U 0.4686274 0.6162291 13773 129 183165 183166 1 165 Convergent + - 0.000000 0 0.000000 0.00000000 1.515671 3.196324 1.0075708 - - - paREP2a 1.456376 3.314142 1.1451607 750 Predicted membrane-associated Zn-dependent proteases 1 M conserved hypothetical protein 0.000000e+00 0 3.515893e-03 3.203284e-04 1.405360e-02 8.625941e-02 2.057246e-01 0 0 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176869 0.5778836 U 0.4686274 0.6162291 13773 129 183166 183167 1 39 Same - - 0.000000 0 0.000000 0.00000000 1.456376 3.314142 1.1451607 750 Predicted membrane-associated Zn-dependent proteases 1 M conserved hypothetical protein 1.474235 3.192644 1.0574795 - - - hypothetical protein 0.000000e+00 0 3.189245e-04 1.138316e-04 2.333057e-02 4.418165e-02 2.622262e-02 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184658 0.6348800 U 0.4686274 0.6162291 13773 129 183167 183168 1 255 Same - - 0.000000 0 0.000000 0.00000000 1.474235 3.192644 1.0574795 - - - hypothetical protein 1.250073 2.757908 1.0916697 - - - hypothetical protein containing C2H2 zinc finger motifs, degenerate 0.000000e+00 0 5.024861e-02 -4.598536e-03 6.857109e-02 -3.029263e-01 1.678248e+00 0 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4396594 0.4125702 U 0.4686274 0.6162291 13773 129 183168 183169 1 141 Same - - 0.000000 0 0.000000 0.00000000 1.250073 2.757908 1.0916697 - - - hypothetical protein containing C2H2 zinc finger motifs, degenerate 1.520102 3.218596 1.1019734 - - - paREP2b 0.000000e+00 0 7.291568e-02 -1.383249e-02 -2.319326e-01 -6.142040e-01 2.592520e+00 0 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3928823 0.4028286 U 0.4686274 0.6162291 13773 129 183169 183170 1 0 Divergent - + 0.000000 0 0.000000 0.00000000 1.520102 3.218596 1.1019734 - - - paREP2b 1.397485 2.853156 1.1505392 - - - paREP2a 0.000000e+00 0 1.503484e-02 -3.703942e-03 -2.717872e-02 -2.770827e-01 1.138815e+00 0 0 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4455922 0.4311406 U 0.4686274 0.6162291 13773 129 183170 183171 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.397485 2.853156 1.1505392 - - - paREP2a 1.309091 2.603651 1.0216741 - - - paREP2a 0.000000e+00 0 7.813550e-03 7.671180e-03 1.544761e-01 4.130553e-01 2.297080e-01 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6403349 0.5710473 U 0.4686274 0.6162291 13773 129 183171 183172 1 -46 Same + + 0.000000 0 0.000000 0.00000000 1.309091 2.603651 1.0216741 - - - paREP2a 1.615891 3.578015 1.1002276 - - - paREP2a 0.000000e+00 0 9.412651e-02 -2.340846e-02 -2.356669e-01 -8.239796e-01 3.297165e+00 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3812910 0.3999544 U 0.4686274 0.6162291 13773 129 183172 183173 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.615891 3.578015 1.1002276 - - - paREP2a 1.502789 3.465189 1.0943058 4920 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 1.279202e-02 8.454660e-03 5.758191e-02 4.659653e-01 1.345758e-01 0 2 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6624433 0.5971986 U 0.4686274 0.6162291 13773 129 183173 183174 1 -11 Convergent + - 0.000000 0 0.000000 0.00000000 1.502789 3.465189 1.0943058 4920 Predicted membrane protein S conserved hypothetical protein 1.391136 2.971396 1.0262325 2058 Ribosomal protein L12E/L44/L45/RPP1/RPP2 J ribosomal protein L12 0.000000e+00 0 1.246646e-02 -3.096989e-03 -1.296095e-02 -2.582894e-01 1.034053e+00 2 0 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4508488 0.4366685 U 0.4686274 0.6162291 13773 129 183174 183175 1 44 Same - - 0.000000 0 0.000000 0.00000000 1.391136 2.971396 1.0262325 2058 Ribosomal protein L12E/L44/L45/RPP1/RPP2 J ribosomal protein L12 1.388107 3.074229 1.0528057 - - - ribosomal protein L38 0.000000e+00 0 9.174978e-06 3.813388e-03 6.627521e-02 2.548808e-01 5.300950e-04 0 1 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5718390 0.6531640 U 0.4686274 0.6162291 13773 129 183175 183176 1 144 Same - - 0.000000 0 0.000000 0.00000000 1.388107 3.074229 1.0528057 - - - ribosomal protein L38 1.229171 2.833892 0.8804654 2096 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 2.526085e-02 1.406350e-02 3.004091e-01 5.145184e-01 2.300759e-01 1 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6796692 0.5708723 U 0.4686274 0.6162291 13773 129 183176 183177 1 112 Divergent - + 0.000000 0 0.000000 0.00000000 1.229171 2.833892 0.8804654 2096 Uncharacterized conserved protein S conserved hypothetical protein 1.521323 3.268754 1.1064235 2513 PEP phosphonomutase and related enzymes G carboxyphosphonoenolpyruvate phosphonomutase (prpB) 0.000000e+00 0 8.535295e-02 -1.553999e-02 -2.739496e-01 -6.284311e-01 2.647176e+00 0 21 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3917124 0.4025539 U 0.4686274 0.6162291 13773 129 183177 183178 1 -7 Same + + 18.212026 0 41.704659 40.79703583 1.521323 3.268754 1.1064235 2513 PEP phosphonomutase and related enzymes G carboxyphosphonoenolpyruvate phosphonomutase (prpB) 1.349814 2.902727 1.0204621 2079 Uncharacterized protein involved in propionate catabolism R propionate catabolism protein prpD 2.292201e-01 18 2.941534e-02 -7.103419e-03 -4.853273e-02 -4.909315e-01 1.985439e+00 21 18 TRUE TRUE 104 TRUE 2.4834224 2.0173004 0.5480306 2.2468137 0.7781393 1.1572856 0.4061864 0.4081529 U 0.4686274 0.8970770 13773 129 183178 183179 1 81 Convergent + - 0.000000 0 0.000000 0.00000000 1.349814 2.902727 1.0204621 2079 Uncharacterized protein involved in propionate catabolism R propionate catabolism protein prpD 1.411358 2.805520 1.1154238 - - - hypothetical protein 0.000000e+00 0 3.787753e-03 4.066653e-03 4.615289e-02 2.341182e-01 2.278725e-01 18 0 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5630735 0.5715668 U 0.4686274 0.6162291 13773 129 183179 183180 1 435 Divergent - + 0.000000 0 0.000000 0.00000000 1.411358 2.805520 1.1154238 - - - hypothetical protein 1.481355 3.279863 1.1353706 - - - P. aerophilum family 66 protein 0.000000e+00 0 4.899530e-03 -1.199521e-03 4.922175e-03 -1.133649e-01 4.592325e-01 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4874524 0.5023186 U 0.4686274 0.6162291 13773 129 183180 183181 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.481355 3.279863 1.1353706 - - - P. aerophilum family 66 protein 1.431463 3.770927 1.2165506 - - - P. aerophilum family 550 protein 0.000000e+00 0 2.489241e-03 -5.971485e-04 1.248455e-02 -3.672792e-02 2.249511e-01 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5099585 0.5726631 U 0.4686274 0.6162291 13773 129 183181 183182 1 393 Same + + 0.000000 0 0.000000 0.00000000 1.431463 3.770927 1.2165506 - - - P. aerophilum family 550 protein 1.625192 3.630217 1.1619830 - - - hypothetical protein 0.000000e+00 0 3.753101e-02 -3.463819e-03 5.593788e-02 -8.819190e-02 1.004610e+00 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4958495 0.4390044 U 0.4686274 0.6162291 13773 129 183182 183183 1 -9 Same + + 0.000000 0 0.000000 0.00000000 1.625192 3.630217 1.1619830 - - - hypothetical protein 1.486705 3.294128 1.1109944 - - - hypothetical protein 0.000000e+00 0 1.917874e-02 6.137179e-03 1.895305e-02 3.819334e-01 2.330303e-01 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6258790 0.5695312 U 0.4686274 0.6162291 13773 129 183183 183184 1 355 Same + + 0.000000 0 0.000000 0.00000000 1.486705 3.294128 1.1109944 - - - hypothetical protein 1.528329 3.403955 1.0545389 - - - conserved within P. aerophilum, authentic frameshift 0.000000e+00 0 1.732594e-03 2.716767e-03 6.436816e-02 2.821578e-01 6.069057e-02 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5852237 0.6202452 U 0.4686274 0.6162291 13773 129 183184 183185 1 361 Same + + 0.000000 0 0.000000 0.00000000 1.528329 3.403955 1.0545389 - - - conserved within P. aerophilum, authentic frameshift 1.347290 2.874330 1.0218892 492 Thioredoxin reductase O thioredoxin reductase (trxB) 0.000000e+00 0 3.277521e-02 -8.009297e-03 -6.041938e-02 -5.325087e-01 2.146461e+00 0 17 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4002874 0.4067434 U 0.4686274 0.6162291 13773 129 183185 183186 1 20 Convergent + - 0.000000 0 0.000000 0.00000000 1.347290 2.874330 1.0218892 492 Thioredoxin reductase O thioredoxin reductase (trxB) 1.440747 3.185132 1.1020370 - - - conserved within P. aerophilum 0.000000e+00 0 8.734167e-03 1.108297e-03 6.462313e-03 3.056881e-03 6.285094e-01 17 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197298 0.4734023 U 0.4686274 0.6162291 13773 129 183186 183187 1 4 Same - - 0.000000 0 0.000000 0.00000000 1.440747 3.185132 1.1020370 - - - conserved within P. aerophilum 1.497607 3.255431 1.0733271 - - - protease, conjectural 0.000000e+00 0 3.233106e-03 -4.920045e-04 2.012098e-02 -1.884782e-03 2.450364e-01 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199564 0.5644275 U 0.4686274 0.6162291 13773 129 183187 183188 1 116 Divergent - + 0.000000 0 0.000000 0.00000000 1.497607 3.255431 1.0733271 - - - protease, conjectural 1.396632 3.079775 1.0801974 185 Ribosomal protein S19 J ribosomal protein S19 0.000000e+00 0 1.019598e-02 -2.530733e-03 -6.660760e-03 -2.231582e-01 8.939898e-01 0 12 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4587726 0.4470060 U 0.4686274 0.6162291 13773 129 183188 183189 1 2 Same + + 0.000000 0 0.000000 -0.01801851 1.396632 3.079775 1.0801974 185 Ribosomal protein S19 J ribosomal protein S19 1.382895 2.909552 1.0171432 186 Ribosomal protein S17 J ribosomal protein S17 2.507089e-02 1 1.886935e-04 3.750982e-03 6.889499e-02 2.552372e-01 1.154429e-02 J 12 1 TRUE TRUE 109 TRUE 0.4469764 0.3087842 0.5480306 0.4469764 0.6329203 0.7074534 0.5722705 0.6421803 Y 1.4497162 0.6618114 13773 129 183189 183190 1 12 Convergent + - 0.000000 0 0.000000 0.00000000 1.382895 2.909552 1.0171432 186 Ribosomal protein S17 J ribosomal protein S17 1.396673 2.878209 1.0506675 - - - paREP2a 0.000000e+00 0 1.898314e-04 3.748149e-03 6.025084e-02 2.548060e-01 1.170980e-02 1 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5716240 0.6420996 U 0.4686274 0.6162291 13773 129 183190 183191 1 13 Same - - 0.000000 0 0.000000 0.00000000 1.396673 2.878209 1.0506675 - - - paREP2a 1.397485 2.853156 1.1505392 - - - paREP2a 0.000000e+00 0 6.590126e-07 2.949806e-03 5.500371e-02 2.024176e-01 5.315674e-05 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5502992 0.6554796 U 0.4686274 0.6162291 13773 129 183191 183192 1 0 Divergent - + 0.000000 0 0.000000 0.00000000 1.397485 2.853156 1.1505392 - - - paREP2a 1.469938 3.112077 1.0631428 - - - paREP2b 0.000000e+00 0 5.249438e-03 -9.997336e-04 2.542006e-03 -1.205601e-01 5.132628e-01 0 0 FALSE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4849817 0.4910513 U 0.4686274 0.6162291 13773 129 183192 183193 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.469938 3.112077 1.0631428 - - - paREP2b 1.441607 3.251895 1.0541867 1948 ERCC4-type nuclease L conserved hypothetical protein 0.000000e+00 0 8.026595e-04 -1.814836e-04 1.798552e-02 1.036630e-03 7.092023e-02 0 3 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198891 0.6175203 U 0.4686274 0.6162291 13773 129 183193 183194 1 56 Convergent + - 0.000000 0 0.000000 -0.13150953 1.441607 3.251895 1.0541867 1948 ERCC4-type nuclease L conserved hypothetical protein 1.441300 3.121957 1.0637401 2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase G beta-glucosidase 4.761494e-02 3 9.433595e-08 9.877100e-05 2.190805e-02 -2.944972e-06 2.120380e-05 0 3 6 TRUE TRUE 110 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7136133 0.8358229 0.5199640 0.6555893 N 0.5492530 0.5624819 13773 129 183194 183195 1 140 Same - - 0.000000 0 0.000000 -0.13150953 1.441300 3.121957 1.0637401 2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase G beta-glucosidase 1.404148 3.142602 1.0553345 589 Universal stress protein UspA and related nucleotide-binding proteins T conserved hypothetical protein 7.264158e-02 2 1.380260e-03 4.768490e-04 3.172284e-02 2.862513e-04 1.385462e-01 0 6 2 FALSE TRUE 109 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.9255497 0.5199359 0.5961785 N 0.5492530 0.5624819 13773 129 183195 183196 1 -7 Same - - 2.856470 0 5.519058 5.51905803 1.404148 3.142602 1.0553345 589 Universal stress protein UspA and related nucleotide-binding proteins T conserved hypothetical protein 1.413744 2.959651 1.0095900 57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase G glyceraldehyde-3-phosphate dehydrogenase 5.118686e-02 2 9.208016e-05 1.778731e-03 3.946636e-02 1.019055e-01 9.954005e-03 0 2 12 FALSE TRUE 108 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 0.8456214 0.5190107 0.6428219 N 0.5492530 0.8654777 13773 129 183196 183197 1 -3 Same - - 4.935912 0 7.598500 6.74458605 1.413744 2.959651 1.0095900 57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase G glyceraldehyde-3-phosphate dehydrogenase 1.425031 3.117098 1.0671041 126 3-phosphoglycerate kinase G phosphoglycerate kinase 1.241971e-02 12 1.274080e-04 9.924914e-04 3.050733e-02 4.738813e-02 9.954005e-03 G 12 69 FALSE TRUE 107 TRUE 2.8363652 1.8091830 0.5480306 2.8096798 0.7776747 0.6196637 0.5186936 0.6428219 Y 1.4497162 0.9077802 13773 129 183197 183198 1 88 Divergent - + 0.000000 0 0.000000 -0.26504093 1.425031 3.117098 1.0671041 126 3-phosphoglycerate kinase G phosphoglycerate kinase 1.361549 2.840454 1.0042868 4914 Predicted nucleotidyltransferase R conserved hypothetical protein 2.897430e-03 3 4.030044e-03 2.368438e-03 6.716423e-02 1.237948e-01 2.919151e-01 69 3 FALSE TRUE 106 FALSE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.5139075 0.5227417 0.5460473 U 0.4686274 0.5447277 13773 129 183198 183199 1 84 Same + + 0.000000 0 0.000000 0.00000000 1.361549 2.840454 1.0042868 4914 Predicted nucleotidyltransferase R conserved hypothetical protein 1.419111 2.987602 1.0608596 441 Threonyl-tRNA synthetase J threonyl-tRNA synthetase 4.116993e-03 3 3.313467e-03 2.900308e-03 3.679644e-02 1.637817e-01 2.345146e-01 3 7 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5373524 0.5359487 0.5687032 U 0.4686274 0.6162291 13773 129 183199 183200 1 62 Same + + 0.000000 0 0.000000 0.00000000 1.419111 2.987602 1.0608596 441 Threonyl-tRNA synthetase J threonyl-tRNA synthetase 1.499984 3.164379 0.9939917 1586 S-adenosylmethionine decarboxylase E conserved hypothetical protein 5.530165e-03 4 6.540312e-03 -1.568581e-03 5.746908e-03 -1.167605e-01 5.450813e-01 0 7 4 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.5496449 0.4859277 0.4841397 N 0.5492530 0.6245624 13773 129 183200 183201 1 159 Same + + 0.000000 0 0.000000 0.00000000 1.499984 3.164379 0.9939917 1586 S-adenosylmethionine decarboxylase E conserved hypothetical protein 1.525072 3.334262 1.1159301 - - - hypothetical protein 0.000000e+00 0 6.294434e-04 3.580132e-03 7.038779e-02 3.295848e-01 1.929605e-02 4 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6036756 0.6380078 U 0.4686274 0.6162291 13773 129 183201 183202 1 526 Convergent + - 0.000000 0 0.000000 0.00000000 1.525072 3.334262 1.1159301 - - - hypothetical protein 1.559429 3.874599 1.1940270 - - - P. aerophilum family 550 protein 0.000000e+00 0 1.180409e-03 7.960062e-03 1.296637e-01 5.015853e-01 1.603537e-02 0 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6732068 0.6397376 U 0.4686274 0.6162291 13773 129 183202 183203 1 8 Same - - 0.000000 0 0.000000 0.00000000 1.559429 3.874599 1.1940270 - - - P. aerophilum family 550 protein 1.494215 3.332750 1.1460650 - - - P. aerophilum family 66 protein 0.000000e+00 0 4.252943e-03 4.626325e-03 4.984587e-02 3.607373e-01 9.518385e-02 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6158891 0.6086719 U 0.4686274 0.6162291 13773 129 183203 183204 1 253 Same - - 0.000000 0 0.000000 0.00000000 1.494215 3.332750 1.1460650 - - - P. aerophilum family 66 protein 1.428247 2.885688 0.9472884 1763 Molybdopterin-guanine dinucleotide biosynthesis protein H molybdopterin-guanine dinucleotide biosynthesis protein B, conjectural 0.000000e+00 0 4.351690e-03 -9.911321e-04 5.852809e-03 -6.328097e-02 3.620289e-01 0 3 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5029481 0.5204865 U 0.4686274 0.6162291 13773 129 183204 183205 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.428247 2.885688 0.9472884 1763 Molybdopterin-guanine dinucleotide biosynthesis protein H molybdopterin-guanine dinucleotide biosynthesis protein B, conjectural 1.356451 3.049854 1.0422265 1695 Predicted transcriptional regulators K conserved hypothetical protein 0.000000e+00 0 5.154680e-03 2.197466e-03 6.796151e-02 1.010202e-01 3.694550e-01 0 3 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5188426 0.5185356 N 0.5492530 0.6245624 13773 129 183205 183206 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.356451 3.049854 1.0422265 1695 Predicted transcriptional regulators K conserved hypothetical protein 1.377329 2.969532 1.0448032 1260 Myo-inositol-1-phosphate synthase I myo-inositol-1-phosphate synthase, conjectural 0.000000e+00 0 4.358846e-04 7.031724e-03 9.399400e-02 4.508811e-01 1.887197e-02 0 0 15 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6563953 0.6382319 N 0.5492530 0.6245624 13773 129 183206 183207 1 58 Same - - 0.000000 0 0.000000 0.00000000 1.377329 2.969532 1.0448032 1260 Myo-inositol-1-phosphate synthase I myo-inositol-1-phosphate synthase, conjectural 1.409955 3.058969 1.0702515 247 Fe-S oxidoreductase C iron-sulfur binding reductase, probable 0.000000e+00 0 1.064425e-03 3.069065e-03 4.705241e-02 1.907753e-01 8.505079e-02 0 15 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5463187 0.6126404 N 0.5492530 0.6245624 13773 129 183207 183208 1 200 Same - - 0.000000 0 0.000000 0.00000000 1.409955 3.058969 1.0702515 247 Fe-S oxidoreductase C iron-sulfur binding reductase, probable 1.418238 3.029034 1.0412114 1468 RecB family exonuclease L conserved hypothetical protein 0.000000e+00 0 6.861188e-05 1.373881e-03 3.523240e-02 7.365375e-02 6.493663e-03 0 0 4 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179430 0.6450314 N 0.5492530 0.6245624 13773 129 183208 183209 1 -19 Same - - 0.000000 0 0.000000 -0.10001087 1.418238 3.029034 1.0412114 1468 RecB family exonuclease L conserved hypothetical protein 1.435345 3.229831 1.1299722 5258 GTPase R GTP-binding protein 4.247656e-02 4 2.926443e-04 5.320741e-04 2.482132e-02 1.347325e-02 3.115780e-02 4 5 FALSE TRUE 103 TRUE 0.4469764 0.2961221 0.5480306 0.4469764 0.7323301 0.8166262 0.5184023 0.6322033 U 0.4686274 0.5559281 13773 129 183209 183210 1 207 Same - - 0.000000 0 0.000000 0.00000000 1.435345 3.229831 1.1299722 5258 GTPase R GTP-binding protein 1.464531 3.670289 1.2207221 - - - hypothetical protein 0.000000e+00 0 8.518646e-04 -2.108499e-04 1.805672e-02 -1.250141e-02 7.548788e-02 5 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176262 0.6162896 U 0.4686274 0.6162291 13773 129 183210 183211 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.464531 3.670289 1.2207221 - - - hypothetical protein 1.480549 3.275692 1.1263432 - - - paREP2a 0.000000e+00 0 2.565614e-04 3.830715e-04 2.693708e-02 8.000900e-02 2.285828e-02 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177633 0.6363673 U 0.4686274 0.6162291 13773 129 183211 183212 1 -27 Same - - 0.000000 0 0.000000 0.00000000 1.480549 3.275692 1.1263432 - - - paREP2a 1.621306 3.578548 1.0859136 - - - paREP2a 0.000000e+00 0 1.981246e-02 4.954006e-03 1.498191e-01 3.310620e-01 2.812336e-01 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6042041 0.5506717 U 0.4686274 0.6162291 13773 129 183212 183213 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.621306 3.578548 1.0859136 - - - paREP2a 1.369367 2.788862 0.9714794 - - - paREP2a 0.000000e+00 0 6.347299e-02 -1.393720e-02 -1.984503e-01 -5.952218e-01 2.436762e+00 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3945146 0.4038977 U 0.4686274 0.6162291 13773 129 183213 183214 1 161 Divergent - + 0.000000 0 0.000000 0.00000000 1.369367 2.788862 0.9714794 - - - paREP2a 1.474356 3.217678 1.1034773 - - - paREP2b 0.000000e+00 0 1.102274e-02 -1.883606e-03 -1.703311e-02 -2.043375e-01 9.425236e-01 0 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4630860 0.4432769 U 0.4686274 0.6162291 13773 129 183214 183215 1 -14 Convergent + - 0.000000 0 0.000000 0.00000000 1.474356 3.217678 1.1034773 - - - paREP2b 1.500976 3.527819 1.2180493 3808 Inorganic pyrophosphatase C vacuolar-type H+-pyrophosphatase 0.000000e+00 0 7.086041e-04 1.138612e-03 3.895489e-02 1.579294e-01 4.136213e-02 0 20 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5337558 0.6275054 U 0.4686274 0.6162291 13773 129 183215 183216 1 99 Divergent - + 0.000000 0 0.000000 0.00000000 1.500976 3.527819 1.2180493 3808 Inorganic pyrophosphatase C vacuolar-type H+-pyrophosphatase 1.508446 3.243134 1.1051663 - - - paREP2a 0.000000e+00 0 5.580178e-05 2.828890e-03 5.583679e-02 2.856087e-01 2.120380e-03 20 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5866818 0.6501030 U 0.4686274 0.6162291 13773 129 183216 183217 1 104 Same + + 0.000000 0 0.000000 0.00000000 1.508446 3.243134 1.1051663 - - - paREP2a 1.382426 3.110270 1.1028439 1269 Archaeal/vacuolar-type H+-ATPase subunit I C H+-transporting ATP synthase subunit I (atpI), conjectural 0.000000e+00 0 1.588108e-02 -3.934788e-03 -2.145627e-02 -3.160108e-01 1.264115e+00 0 1 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4358975 0.4257281 U 0.4686274 0.6162291 13773 129 183217 183218 1 0 Same + + 0.000000 0 0.000000 -0.07232066 1.382426 3.110270 1.1028439 1269 Archaeal/vacuolar-type H+-ATPase subunit I C H+-transporting ATP synthase subunit I (atpI), conjectural 1.410175 3.233160 1.0941575 685 5,10-methylenetetrahydrofolate reductase E conserved hypothetical protein 4.578021e-02 1 7.700140e-04 2.842657e-03 4.621021e-02 1.773486e-01 6.414149e-02 0 1 3 TRUE TRUE 100 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.8313457 0.5410568 0.6193126 N 0.5492530 0.5660839 13773 129 183218 183219 1 40 Same + + 0.000000 0 0.000000 0.00000000 1.410175 3.233160 1.0941575 685 5,10-methylenetetrahydrofolate reductase E conserved hypothetical protein 1.406889 3.154444 1.0793532 1192 ATPases involved in chromosome partitioning D conserved hypothetical protein 5.631536e-04 1 1.080102e-05 1.834362e-03 4.290101e-02 1.064572e-01 7.215181e-04 0 3 1 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.5195448 0.6523872 N 0.5492530 0.6245624 13773 129 183219 183220 1 -46 Convergent + - 0.000000 0 0.000000 0.00000000 1.406889 3.154444 1.0793532 1192 ATPases involved in chromosome partitioning D conserved hypothetical protein 1.452413 3.284988 1.0943351 - - - hypothetical protein 0.000000e+00 0 2.072448e-03 -4.539153e-05 1.517979e-02 -3.652943e-02 2.001927e-01 1 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5102237 0.5800294 U 0.4686274 0.6162291 13773 129 183220 183221 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.452413 3.284988 1.0943351 - - - hypothetical protein 1.407706 3.016095 1.0349985 - - - conserved protein 0.000000e+00 0 1.998739e-03 -4.455834e-05 2.506092e-02 -3.570484e-02 1.933839e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5104883 0.5820196 U 0.4686274 0.6162291 13773 129 183221 183222 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.407706 3.016095 1.0349985 - - - conserved protein 1.514443 3.366660 1.0815500 255 Ribosomal protein L29 J ribosomal protein L29 0.000000e+00 0 1.139292e-02 -2.754498e-03 -6.220125e-03 -1.953565e-01 8.467389e-01 0 1 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4655272 0.4508449 U 0.4686274 0.6162291 13773 129 183222 183223 1 39 Same - - 0.000000 0 0.000000 0.00000000 1.514443 3.366660 1.0815500 255 Ribosomal protein L29 J ribosomal protein L29 1.387399 2.953274 1.0392706 92 Ribosomal protein S3 J ribosomal protein S3 1.557260e-03 1 1.614026e-02 -4.034842e-03 -2.613434e-02 -3.086001e-01 1.238361e+00 J 1 8 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.4376053 0.4265891 Y 1.4497162 0.7118045 13773 129 183223 183224 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.387399 2.953274 1.0392706 92 Ribosomal protein S3 J ribosomal protein S3 1.608678 3.479212 1.1502067 - - - conserved protein part 2, authentic frameshift 0.000000e+00 0 4.896445e-02 -1.006531e-02 -4.452468e-02 -4.624973e-01 1.976797e+00 8 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4099790 0.4082992 U 0.4686274 0.6162291 13773 129 183224 183225 1 -48 Same - - 0.000000 0 0.000000 0.00000000 1.608678 3.479212 1.1502067 - - - conserved protein part 2, authentic frameshift 1.395806 3.069681 1.0449615 - - - conserved protein part 1, authentic frameshift 0.000000e+00 0 4.531438e-02 -8.742950e-03 -1.364645e-01 -4.050232e-01 1.797616e+00 0 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4184629 0.4108104 U 0.4686274 0.6162291 13773 129 183225 183226 1 366 Same - - 0.000000 0 0.000000 0.00000000 1.395806 3.069681 1.0449615 - - - conserved protein part 1, authentic frameshift 1.339556 2.838446 1.0054300 91 Ribosomal protein L22 J ribosomal protein L22 0.000000e+00 0 3.164113e-03 6.216649e-03 1.173407e-01 3.835019e-01 1.402655e-01 0 13 FALSE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6270495 0.5956690 U 0.4686274 0.6162291 13773 129 183226 183227 1 100 Same - - 0.000000 0 0.000000 0.00000000 1.339556 2.838446 1.0054300 91 Ribosomal protein L22 J ribosomal protein L22 1.518476 3.303035 1.1391530 - - - hypothetical protein 0.000000e+00 0 3.201238e-02 -7.502363e-03 -8.731693e-02 -5.102688e-01 2.090610e+00 13 0 FALSE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4043835 0.4072458 U 0.4686274 0.6162291 13773 129 183227 183228 1 71 Divergent - + 0.000000 0 0.000000 0.00000000 1.518476 3.303035 1.1391530 - - - hypothetical protein 1.411016 3.406518 1.1534596 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H conserved hypothetical protein 0.000000e+00 0 1.154767e-02 -2.708617e-03 -1.822013e-02 -1.858937e-01 8.382857e-01 0 1 FALSE TRUE 94 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4684601 0.4517945 U 0.4686274 0.6162291 13773 129 183228 183229 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.411016 3.406518 1.1534596 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H conserved hypothetical protein 1.435928 3.131608 1.0806831 1011 Predicted hydrolase (HAD superfamily) R conserved hypothetical protein 7.562104e-04 1 6.206287e-04 6.244208e-04 2.450574e-02 1.609368e-02 6.298058e-02 1 4 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5180940 0.6195629 U 0.4686274 0.6162291 13773 129 183229 183230 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.435928 3.131608 1.0806831 1011 Predicted hydrolase (HAD superfamily) R conserved hypothetical protein 1.468698 3.154253 1.0507944 - - - hypothetical protein 0.000000e+00 0 1.073884e-03 -2.676239e-04 1.776174e-02 -1.353332e-02 9.518385e-02 4 0 TRUE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5172398 0.6086719 U 0.4686274 0.6162291 13773 129 183230 183231 1 53 Same - - 0.000000 0 0.000000 0.00000000 1.468698 3.154253 1.0507944 - - - hypothetical protein 1.554319 3.605177 1.1744064 - - - conserved within P. aerophilum 0.000000e+00 0 7.330846e-03 1.781178e-03 6.770605e-02 1.939777e-01 2.534655e-01 0 1 FALSE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5475706 0.5613233 U 0.4686274 0.6162291 13773 129 183231 183232 1 439 Divergent - + 0.000000 0 0.000000 -0.05918887 1.554319 3.605177 1.1744064 - - - conserved within P. aerophilum 1.423033 3.179251 1.1123817 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 2.915931e-02 1 1.723598e-02 -2.918980e-03 -3.825220e-02 -1.456289e-01 9.041777e-01 1 9 FALSE TRUE 94 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.7296993 0.4779114 0.4460064 U 0.4686274 0.5589164 13773 129 183232 183233 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.423033 3.179251 1.1123817 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.409373 3.139282 1.1094765 - - - hypothetical protein 0.000000e+00 0 1.865822e-04 1.191676e-03 3.711246e-02 6.096092e-02 1.584159e-02 9 0 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184822 0.6399079 U 0.4686274 0.6162291 13773 129 183233 183234 1 9 Convergent + - 0.000000 0 0.000000 0.00000000 1.409373 3.139282 1.1094765 - - - hypothetical protein 1.295717 2.806953 0.9200014 328 Ribonuclease HI L hypothetical protein 0.000000e+00 0 1.291769e-02 6.541418e-03 1.542826e-01 3.028539e-01 4.038051e-01 0 0 TRUE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5931175 0.5117668 U 0.4686274 0.6162291 13773 129 183234 183235 1 783 Same - - 0.000000 0 0.000000 0.00000000 1.295717 2.806953 0.9200014 328 Ribonuclease HI L hypothetical protein 1.347503 2.912829 1.0014635 4978 Transcriptional regulator, effector-binding domain/component KT hypothetical protein 0.000000e+00 0 2.681810e-03 1.617304e-02 1.757016e-01 7.585977e-01 2.475249e-02 0 0 FALSE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7703495 0.6354990 U 0.4686274 0.6162291 13773 129 183235 183236 1 44 Divergent - + 0.000000 0 0.000000 0.00000000 1.347503 2.912829 1.0014635 4978 Transcriptional regulator, effector-binding domain/component KT hypothetical protein 1.572506 3.406962 1.1022781 1637 Predicted nuclease of the RecB family L conserved hypothetical protein 0.000000e+00 0 5.062620e-02 -1.258238e-02 -1.165374e-01 -6.443805e-01 2.577713e+00 0 14 FALSE TRUE 94 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3903043 0.4028974 U 0.4686274 0.6162291 13773 129 183236 183237 1 197 Same + + 0.000000 0 0.000000 0.00000000 1.572506 3.406962 1.1022781 1637 Predicted nuclease of the RecB family L conserved hypothetical protein 1.368134 2.798863 1.0216147 - - - conserved within P. aerophilum 0.000000e+00 0 4.176776e-02 -1.008369e-02 -1.168105e-01 -5.474438e-01 2.207608e+00 14 0 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3989104 0.4056432 U 0.4686274 0.6162291 13773 129 183237 183238 1 -17 Convergent + - 0.000000 0 0.000000 0.00000000 1.368134 2.798863 1.0216147 - - - conserved within P. aerophilum 1.353436 2.908806 1.0250222 160 4-aminobutyrate aminotransferase and related aminotransferases E 4-aminobutyrate aminotransferase 0.000000e+00 0 2.160410e-04 8.155714e-03 1.228607e-01 5.126772e-01 6.743397e-03 0 44 TRUE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6785805 0.6447284 U 0.4686274 0.6162291 13773 129 183238 183239 1 896 Divergent - + 0.000000 0 0.000000 0.00000000 1.353436 2.908806 1.0250222 160 4-aminobutyrate aminotransferase and related aminotransferases E 4-aminobutyrate aminotransferase 1.422413 3.177433 1.1218406 - - - P. aerophilum family 59 protein 0.000000e+00 0 4.757790e-03 2.838781e-03 3.169439e-02 1.513009e-01 3.121576e-01 44 0 FALSE TRUE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5307995 0.5377013 U 0.4686274 0.6162291 13773 129 183239 183240 1 -22 Same + + 0.000000 0 0.000000 0.00000000 1.422413 3.177433 1.1218406 - - - P. aerophilum family 59 protein 1.430001 3.566885 1.1948037 - - - hypothetical protein 0.000000e+00 0 5.758354e-05 6.199269e-04 2.701535e-02 2.343020e-02 6.743397e-03 0 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174195 0.6447284 U 0.4686274 0.6162291 13773 129 183240 183241 1 61 Same + + 0.000000 0 0.000000 0.00000000 1.430001 3.566885 1.1948037 - - - hypothetical protein 1.647826 3.565597 1.0726948 - - - hypothetical protein 0.000000e+00 0 4.744773e-02 -4.202020e-03 6.843413e-02 -1.093109e-01 1.099038e+00 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4883835 0.4327437 U 0.4686274 0.6162291 13773 129 183241 183242 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.647826 3.565597 1.0726948 - - - hypothetical protein 1.388061 2.982339 1.0012146 - - - hypothetical protein 0.000000e+00 0 6.747820e-02 -1.244057e-02 -2.125248e-01 -4.815394e-01 2.097273e+00 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4084238 0.4071738 U 0.4686274 0.6162291 13773 129 183242 183243 1 1 Same + + 0.000000 0 0.000000 0.00000000 1.388061 2.982339 1.0012146 - - - hypothetical protein 1.462467 3.088877 1.0718748 - - - hypothetical protein 0.000000e+00 0 5.536337e-03 -7.013615e-04 2.662718e-03 -1.048033e-01 5.182232e-01 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4896558 0.4901366 U 0.4686274 0.6162291 13773 129 183243 183244 1 332 Convergent + - 0.000000 0 0.000000 0.00000000 1.462467 3.088877 1.0718748 - - - hypothetical protein 1.472821 3.662889 1.1531945 - - - conserved within P. aerophilum 0.000000e+00 0 1.072049e-04 2.373038e-04 2.436694e-02 5.939891e-02 8.201158e-03 0 0 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185928 0.6439704 U 0.4686274 0.6162291 13773 129 183244 183245 1 40 Same - - 0.000000 0 0.000000 0.00000000 1.472821 3.662889 1.1531945 - - - conserved within P. aerophilum 1.374909 3.035140 1.0549031 396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component O ABC transporter, putative 0.000000e+00 0 9.586831e-03 -1.638923e-03 1.526452e-02 -1.849466e-01 8.538157e-01 0 55 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4687349 0.4498973 U 0.4686274 0.6162291 13773 129 183245 183246 1 44 Same - - 0.000000 0 0.000000 0.00000000 1.374909 3.035140 1.0549031 396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component O ABC transporter, putative 1.213085 2.834179 1.1626772 - - - paREP2a 0.000000e+00 0 2.618695e-02 1.822676e-02 3.632147e-01 6.303677e-01 1.357043e-01 55 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7293391 0.5968702 U 0.4686274 0.6162291 13773 129 183246 183247 1 52 Same - - 0.000000 0 0.000000 0.00000000 1.213085 2.834179 1.1626772 - - - paREP2a 1.315401 2.674295 1.0956591 - - - paREP2a 0.000000e+00 0 1.046858e-02 3.240792e-02 3.024049e-01 9.064412e-01 8.481519e-03 0 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8061115 0.6437931 U 0.4686274 0.6162291 13773 129 183247 183248 1 199 Divergent - + 0.000000 0 0.000000 0.00000000 1.315401 2.674295 1.0956591 - - - paREP2a 1.362978 3.062382 1.1148174 - - - paREP2b 0.000000e+00 0 2.263554e-03 1.202371e-02 1.342090e-01 6.418885e-01 3.981602e-02 0 0 FALSE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7340133 0.6280980 U 0.4686274 0.6162291 13773 129 183248 183249 1 69 Same + + 0.000000 0 0.000000 0.00000000 1.362978 3.062382 1.1148174 - - - paREP2b 1.323758 2.843331 1.0042994 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O ABC transporter subunit, putative 0.000000e+00 0 1.538226e-03 1.128486e-02 1.742021e-01 6.272260e-01 3.197592e-02 0 50 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7280731 0.6315628 U 0.4686274 0.6162291 13773 129 183249 183250 1 52 Same + + 0.000000 0 0.000000 0.00000000 1.323758 2.843331 1.0042994 719 ABC-type transport system involved in Fe-S cluster assembly, permease component O ABC transporter subunit, putative 1.650916 3.421171 1.0768283 - - - hypothetical protein 0.000000e+00 0 1.070327e-01 -2.546620e-02 -2.172940e-01 -8.279111e-01 3.313909e+00 50 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3808126 0.3998176 U 0.4686274 0.6162291 13773 129 183250 183251 1 302 Same + + 0.000000 0 0.000000 0.00000000 1.650916 3.421171 1.0768283 - - - hypothetical protein 1.319585 2.848840 0.9910110 - - - hypothetical protein 0.000000e+00 0 1.097804e-01 -2.629876e-02 -3.437319e-01 -8.400969e-01 3.361580e+00 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3805732 0.3997492 U 0.4686274 0.6162291 13773 129 183251 183252 1 161 Same + + 0.000000 0 0.000000 0.00000000 1.319585 2.848840 0.9910110 - - - hypothetical protein 1.477350 3.192715 1.0777050 - - - hypothetical protein 0.000000e+00 0 2.488974e-02 -3.421325e-03 -6.167411e-02 -3.051132e-01 1.534328e+00 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4389167 0.4161356 U 0.4686274 0.6162291 13773 129 183252 183253 1 136 Same + + 0.000000 0 0.000000 0.00000000 1.477350 3.192715 1.0777050 - - - hypothetical protein 1.339046 2.782547 0.9952111 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 0.000000e+00 0 1.912797e-02 -2.916180e-03 1.698318e-02 -2.840261e-01 1.384189e+00 0 1 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4443634 0.4204509 U 0.4686274 0.6162291 13773 129 183253 183254 1 88 Same + + 0.000000 0 0.000000 0.00000000 1.339046 2.782547 0.9952111 189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) HJ ribosomal protein S6 modification protein (rimK) 1.512583 3.320114 1.1141327 - - - hypothetical protein 0.000000e+00 0 3.011526e-02 -6.874566e-03 -8.218636e-02 -4.858002e-01 2.009301e+00 1 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4070836 0.4078976 U 0.4686274 0.6162291 13773 129 183254 183255 1 -31 Same + + 0.000000 0 0.000000 0.00000000 1.512583 3.320114 1.1141327 - - - hypothetical protein 1.507498 3.467639 1.1493302 - - - hypothetical protein 0.000000e+00 0 2.586499e-05 3.433073e-03 5.936323e-02 3.214920e-01 6.808775e-04 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6002714 0.6526075 U 0.4686274 0.6162291 13773 129 183255 183256 1 261 Convergent + - 0.000000 0 0.000000 0.00000000 1.507498 3.467639 1.1493302 - - - hypothetical protein 1.233927 2.735081 1.0263236 - - - conserved within P. aerophilum part 2, authentic frameshift 0.000000e+00 0 7.484069e-02 -1.220084e-02 -9.815062e-03 -5.511291e-01 2.398576e+00 0 0 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3984502 0.4040709 U 0.4686274 0.6162291 13773 129 183256 183257 1 118 Same - - 0.000000 0 0.000000 0.00000000 1.233927 2.735081 1.0263236 - - - conserved within P. aerophilum part 2, authentic frameshift 1.437745 3.219245 1.0745759 - - - conserved within P. aerophilum part 1, authentic frameshift 0.000000e+00 0 4.154169e-02 2.967921e-03 -6.418413e-02 3.816684e-02 9.144232e-01 0 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180137 0.4453835 U 0.4686274 0.6162291 13773 129 183257 183258 1 20 Same - - 0.000000 0 0.000000 0.00000000 1.437745 3.219245 1.0745759 - - - conserved within P. aerophilum part 1, authentic frameshift 1.504044 3.176954 1.0347545 - - - hypothetical protein 0.000000e+00 0 4.395558e-03 -7.185721e-04 1.890283e-02 -2.037921e-02 3.242791e-01 0 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5153553 0.5331555 U 0.4686274 0.6162291 13773 129 183258 183259 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.504044 3.176954 1.0347545 - - - hypothetical protein 1.550475 3.346463 1.0405616 - - - hypothetical protein 0.000000e+00 0 2.155822e-03 5.216792e-03 9.962498e-02 3.945414e-01 4.486724e-02 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6317926 0.6260343 U 0.4686274 0.6162291 13773 129 183259 183260 1 508 Divergent - + 0.000000 0 0.000000 0.00000000 1.550475 3.346463 1.0405616 - - - hypothetical protein 1.536280 3.347254 1.1226469 675 Transposase and inactivated derivatives L paREP12 0.000000e+00 0 2.014921e-04 8.410804e-03 1.124475e-01 5.205438e-01 1.781708e-03 0 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6844407 0.6506613 U 0.4686274 0.6162291 13773 129 183260 183261 1 181 Same + + 0.000000 0 0.000000 0.00000000 1.536280 3.347254 1.1226469 675 Transposase and inactivated derivatives L paREP12 1.741531 3.988302 1.1717687 - - - paREP13 0.000000e+00 0 4.212793e-02 2.462903e-02 5.041842e-01 6.883224e-01 7.933107e-02 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7496520 0.6149078 U 0.4686274 0.6162291 13773 129 183261 183262 1 -55 Convergent + - 0.000000 0 0.000000 0.00000000 1.741531 3.988302 1.1717687 - - - paREP13 1.311343 2.909454 1.0539343 - - - hypothetical protein 0.000000e+00 0 1.850620e-01 -4.063391e-02 -6.183315e-01 -9.039415e-01 3.619630e+00 0 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3788952 0.3992700 U 0.4686274 0.6162291 13773 129 183262 183263 1 35 Same - - 0.000000 0 0.000000 0.00000000 1.311343 2.909454 1.0539343 - - - hypothetical protein 1.392666 3.166673 1.1007181 - - - hypothetical protein 0.000000e+00 0 6.613482e-03 8.224711e-03 7.585161e-02 4.385529e-01 1.967736e-01 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6508149 0.5806302 U 0.4686274 0.6162291 13773 129 183263 183264 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.392666 3.166673 1.1007181 - - - hypothetical protein 1.369438 2.890527 0.9973726 1325 Predicted exosome subunit J conserved protein 0.000000e+00 0 5.395176e-04 4.812926e-03 8.531006e-02 3.152899e-01 3.420938e-02 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5979459 0.6303843 U 0.4686274 0.6162291 13773 129 183264 183265 1 69 Divergent - + 0.000000 0 0.000000 0.00000000 1.369438 2.890527 0.9973726 1325 Predicted exosome subunit J conserved protein 1.319619 2.829927 0.9873312 1632 Ribosomal protein L15E J ribosomal protein L15 0.000000e+00 0 2.481981e-03 1.079945e-02 1.740481e-01 5.945321e-01 5.623777e-02 J 0 6 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7184941 0.6216788 Y 1.4497162 0.7118045 13773 129 183265 183266 1 99 Convergent + - 0.000000 0 0.000000 0.00000000 1.319619 2.829927 0.9873312 1632 Ribosomal protein L15E J ribosomal protein L15 1.374352 3.011704 1.0764663 - - - hypothetical protein 0.000000e+00 0 2.995753e-03 1.015191e-02 1.104123e-01 5.690128e-01 7.051205e-02 6 0 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7071471 0.6176510 U 0.4686274 0.6162291 13773 129 183266 183267 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.374352 3.011704 1.0764663 - - - hypothetical protein 1.321866 2.859727 0.9120978 1351 Predicted alternative thymidylate synthase F conserved hypothetical protein 0.000000e+00 0 2.754847e-03 9.978816e-03 1.649462e-01 5.646395e-01 6.689151e-02 0 2 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7047620 0.6185855 U 0.4686274 0.6162291 13773 129 183267 183268 1 106 Divergent - + 0.000000 0 0.000000 0.00000000 1.321866 2.859727 0.9120978 1351 Predicted alternative thymidylate synthase F conserved hypothetical protein 1.331535 3.129939 1.0796021 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase, putative 0.000000e+00 0 9.348480e-05 1.552489e-02 1.961357e-01 7.713318e-01 7.215181e-04 0 2 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7740259 0.6523872 N 0.5492530 0.6245624 13773 129 183268 183269 1 -31 Convergent + - 0.000000 0 0.000000 0.00000000 1.331535 3.129939 1.0796021 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase, putative 1.345210 2.867779 0.9944973 1190 Lysyl-tRNA synthetase (class II) J lysyl-tRNA synthetase 0.000000e+00 0 1.870189e-04 1.272689e-02 1.616939e-01 6.996417e-01 3.138751e-03 0 0 54 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7518639 0.6484515 N 0.5492530 0.6245624 13773 129 183269 183270 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.345210 2.867779 0.9944973 1190 Lysyl-tRNA synthetase (class II) J lysyl-tRNA synthetase 1.432723 3.228347 1.0942396 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R conserved hypothetical protein 0.000000e+00 0 7.658519e-03 1.982415e-03 1.616940e-02 6.456321e-02 5.315674e-01 54 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182946 0.4872443 U 0.4686274 0.6162291 13773 129 183270 183271 1 28 Same - - 0.000000 0 0.000000 0.00000000 1.432723 3.228347 1.0942396 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R conserved hypothetical protein 1.432499 3.244769 1.0844549 - - - hypothetical protein 0.000000e+00 0 5.000399e-08 3.527376e-04 2.488333e-02 6.738096e-03 2.120380e-05 0 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192915 0.6555893 U 0.4686274 0.6162291 13773 129 183271 183272 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.432499 3.244769 1.0844549 - - - hypothetical protein 1.336623 2.941711 0.9439039 43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases H conserved hypothetical protein 0.000000e+00 0 9.192376e-03 2.168408e-03 7.863580e-02 7.172185e-02 5.854657e-01 0 26 FALSE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180012 0.4789857 U 0.4686274 0.6162291 13773 129 183272 183273 1 200 Same - - 0.000000 0 0.000000 -0.28560091 1.336623 2.941711 0.9439039 43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases H conserved hypothetical protein 1.350479 3.068674 1.0357223 1814 Uncharacterized membrane protein S conserved hypothetical protein 3.696649e-04 5 1.920115e-04 1.158188e-02 1.485664e-01 6.578850e-01 5.656702e-03 26 5 FALSE TRUE 95 TRUE 0.4469764 0.2563770 0.5480306 0.4469764 0.7448207 0.4467420 0.7378746 0.6459298 U 0.4686274 0.5433937 13773 129 183273 183274 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.350479 3.068674 1.0357223 1814 Uncharacterized membrane protein S conserved hypothetical protein 1.399679 3.175925 1.0053583 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 2.420587e-03 5.218646e-03 6.268589e-02 3.280510e-01 1.230109e-01 5 0 FALSE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6028852 0.6000329 U 0.4686274 0.6162291 13773 129 183274 183275 1 643 Divergent - + 0.000000 0 0.000000 0.00000000 1.399679 3.175925 1.0053583 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.560392 3.280478 1.0679301 - - - rRNA intron-encoded homing endonuclease, possible 0.000000e+00 0 2.582859e-02 -5.636764e-03 -2.178926e-02 -3.306520e-01 1.449963e+00 0 0 FALSE TRUE 93 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4324111 0.4184889 U 0.4686274 0.6162291 13773 129 183275 183276 1 4592 Same + + 0.000000 0 0.000000 0.00000000 1.560392 3.280478 1.0679301 - - - rRNA intron-encoded homing endonuclease, possible 1.443150 3.233012 1.1058876 - - - hypothetical protein 0.000000e+00 0 1.374550e-02 -8.984190e-04 -1.976554e-02 1.377717e-02 5.819477e-01 0 0 TRUE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183178 0.4794292 U 0.4686274 0.6162291 13773 129 183276 183277 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.443150 3.233012 1.1058876 - - - hypothetical protein 1.470511 3.230770 1.0760869 - - - conserved within P. aerophilum 0.000000e+00 0 7.486306e-04 -1.575849e-04 1.965088e-02 4.863327e-03 6.649511e-02 0 0 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5194953 0.6186810 U 0.4686274 0.6162291 13773 129 183277 183278 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.470511 3.230770 1.0760869 - - - conserved within P. aerophilum 1.552939 3.295793 1.1039582 - - - conserved within P. aerophilum 0.000000e+00 0 6.794355e-03 1.941432e-03 6.869585e-02 2.074315e-01 2.278725e-01 0 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5526212 0.5715668 U 0.4686274 0.6162291 13773 129 183278 183279 1 346 Convergent + - 0.000000 0 0.000000 0.00000000 1.552939 3.295793 1.1039582 - - - conserved within P. aerophilum 1.477559 3.227649 1.0835072 666 FOG: Ankyrin repeat R hypothetical protein with 4 ankyrin repeats 0.000000e+00 0 5.682166e-03 2.657104e-03 2.735740e-02 2.588560e-01 1.673268e-01 0 3 TRUE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5731403 0.5882371 U 0.4686274 0.6162291 13773 129 183279 183280 1 152 Divergent - + 0.000000 0 0.000000 0.00000000 1.477559 3.227649 1.0835072 666 FOG: Ankyrin repeat R hypothetical protein with 4 ankyrin repeats 1.483605 3.268526 1.1161055 - - - conserved within P. aerophilum 0.000000e+00 0 3.654781e-05 8.428674e-04 3.148899e-02 1.356289e-01 2.565660e-03 3 0 FALSE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5265850 0.6491703 U 0.4686274 0.6162291 13773 129 183280 183281 1 14 Same + + 0.000000 0 0.000000 0.00000000 1.483605 3.268526 1.1161055 - - - conserved within P. aerophilum 1.690258 3.818338 1.1169228 - - - hypothetical protein 0.000000e+00 0 4.270542e-02 7.694276e-03 2.529615e-01 3.808508e-01 3.260296e-01 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6255873 0.5324841 U 0.4686274 0.6162291 13773 129 183281 183282 1 287 Same + + 0.000000 0 0.000000 0.00000000 1.690258 3.818338 1.1169228 - - - hypothetical protein 1.688799 3.676240 1.1046154 - - - paREP7 0.000000e+00 0 2.126835e-06 5.670802e-02 6.820198e-01 9.313804e-01 5.889944e-07 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8080425 0.6559820 U 0.4686274 0.6162291 13773 129 183282 183283 1 -103 Same + + 0.000000 0 0.000000 0.00000000 1.688799 3.676240 1.1046154 - - - paREP7 1.457895 3.017247 1.0219153 - - - paREP7 0.000000e+00 0 5.331689e-02 1.543588e-03 -1.042382e-01 1.502943e-01 6.543233e-01 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5305335 0.4698403 U 0.4686274 0.6162291 13773 129 183283 183284 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.457895 3.017247 1.0219153 - - - paREP7 1.356548 3.138884 1.0855686 - - - paREP7 0.000000e+00 0 1.027108e-02 -6.166675e-04 3.626417e-02 -1.157398e-01 8.076533e-01 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4865159 0.4542712 U 0.4686274 0.6162291 13773 129 183284 183285 1 526 Convergent + - 0.000000 0 0.000000 0.00000000 1.356548 3.138884 1.0855686 - - - paREP7 1.485522 3.227949 0.9503101 2445 Uncharacterized conserved protein S paREP11 0.000000e+00 0 1.663424e-02 -3.236979e-03 -3.699601e-02 -3.061687e-01 1.334087e+00 0 1 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4385436 0.4227586 U 0.4686274 0.6162291 13773 129 183285 183286 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.485522 3.227949 0.9503101 2445 Uncharacterized conserved protein S paREP11 1.488832 3.163130 1.0609744 - - - conserved within P. aerophilum 0.000000e+00 0 1.095596e-05 1.277780e-03 3.627943e-02 1.787038e-01 4.617716e-04 1 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5420833 0.6534780 U 0.4686274 0.6162291 13773 129 183286 183287 1 1162 Divergent - + 0.000000 0 0.000000 0.00000000 1.488832 3.163130 1.0609744 - - - conserved within P. aerophilum 1.474347 3.080635 1.0466614 2513 PEP phosphonomutase and related enzymes G isocitrate lyase 0.000000e+00 0 2.098104e-04 8.594007e-04 2.856450e-02 1.334455e-01 1.584159e-02 0 12 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5255413 0.6399079 U 0.4686274 0.6162291 13773 129 183287 183288 1 -3 Same + + 0.000000 0 0.000000 -0.37949617 1.474347 3.080635 1.0466614 2513 PEP phosphonomutase and related enzymes G isocitrate lyase 1.515150 3.202444 1.0555293 517 FOG: CBS domain R conserved protein with 2 CBS domains 2.142647e-02 7 1.664826e-03 1.463504e-03 4.683422e-02 1.828085e-01 8.194620e-02 12 7 TRUE TRUE 100 TRUE 0.4469764 0.2454672 0.5480306 0.4469764 0.7596462 0.6873026 0.5431221 0.6136849 U 0.4686274 0.5399427 13773 129 183288 183289 1 12 Same + + 0.000000 0 0.000000 0.00000000 1.515150 3.202444 1.0555293 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.495120 3.115176 0.9935961 - - - paREP7 0.000000e+00 0 4.011798e-04 2.787912e-03 4.786756e-02 2.821908e-01 1.415059e-02 7 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5854660 0.6408729 U 0.4686274 0.6162291 13773 129 183289 183290 1 133 Same + + 0.000000 0 0.000000 0.00000000 1.495120 3.115176 0.9935961 - - - paREP7 1.365786 3.052105 1.0584864 - - - conserved within P. aerophilum 0.000000e+00 0 1.672726e-02 -3.743347e-03 -9.275530e-03 -3.277642e-01 1.357234e+00 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4339721 0.4220582 U 0.4686274 0.6162291 13773 129 183290 183291 1 195 Same + + 0.000000 0 0.000000 0.00000000 1.365786 3.052105 1.0584864 - - - conserved within P. aerophilum 1.352580 3.249953 1.0959051 1132 ABC-type multidrug transport system, ATPase and permease components V ATP binding protein, degenerate 0.000000e+00 0 1.744011e-04 8.459023e-03 1.258278e-01 5.273879e-01 5.541848e-03 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6874196 0.6460120 U 0.4686274 0.6162291 13773 129 183291 183292 1 970 Same + + 0.000000 0 0.000000 0.00000000 1.352580 3.249953 1.0959051 1132 ABC-type multidrug transport system, ATPase and permease components V ATP binding protein, degenerate 1.582283 3.631991 1.0936747 - - - hypothetical protein 0.000000e+00 0 5.276341e-02 -1.293361e-02 -1.117739e-01 -6.359161e-01 2.548225e+00 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3907742 0.4030349 U 0.4686274 0.6162291 13773 129 183292 183293 1 25 Convergent + - 0.000000 0 0.000000 0.00000000 1.582283 3.631991 1.0936747 - - - hypothetical protein 1.339170 2.837672 0.9811342 5493 Uncharacterized conserved protein containing a coiled-coil domain S conserved hypothetical protein 0.000000e+00 0 5.910378e-02 -1.468882e-02 -1.625333e-01 -6.952938e-01 2.781190e+00 0 2 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3879478 0.4020739 U 0.4686274 0.6162291 13773 129 183293 183294 1 185 Same - - 0.000000 0 0.000000 0.00000000 1.339170 2.837672 0.9811342 5493 Uncharacterized conserved protein containing a coiled-coil domain S conserved hypothetical protein 1.441432 3.635180 1.2324555 306 Phosphate/sulphate permeases P phosphate permease, conjectural 3.728161e-04 1 1.045749e-02 1.117812e-03 2.077101e-03 -1.282830e-03 7.010688e-01 2 1 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.5199848 0.4647282 U 0.4686274 0.6162291 13773 129 183294 183295 1 401 Same - - 0.000000 0 0.000000 0.00000000 1.441432 3.635180 1.2324555 306 Phosphate/sulphate permeases P phosphate permease, conjectural 1.426771 3.099066 1.0692916 2132 Putative multicopper oxidases Q multicopper oxidase 3.554731e-03 1 2.149383e-04 2.452462e-04 2.489271e-02 -2.355978e-04 2.403333e-02 0 1 17 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5281729 0.5199757 0.6357428 N 0.5492530 0.6245624 13773 129 183295 183296 1 295 Divergent - + 0.000000 0 0.000000 0.00000000 1.426771 3.099066 1.0692916 2132 Putative multicopper oxidases Q multicopper oxidase 1.482933 3.181296 1.0168500 - - - paREP6 0.000000e+00 0 3.154167e-03 -7.765735e-04 1.264460e-02 -5.948843e-02 2.927449e-01 17 0 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5039448 0.5451177 U 0.4686274 0.6162291 13773 129 183296 183297 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.482933 3.181296 1.0168500 - - - paREP6 1.428808 3.189057 1.0793402 - - - conserved hypothetical protein 0.000000e+00 0 2.929519e-03 -7.123272e-04 1.117795e-02 -5.086261e-02 2.691563e-01 0 2 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5065612 0.5538632 U 0.4686274 0.6162291 13773 129 183297 183298 1 -52 Same + + 0.000000 0 0.000000 0.00000000 1.428808 3.189057 1.0793402 - - - conserved hypothetical protein 1.424470 3.063779 1.0645230 - - - paREP6 0.000000e+00 0 1.882497e-05 6.080489e-04 2.839266e-02 2.316515e-02 2.050290e-03 2 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174458 0.6502033 U 0.4686274 0.6162291 13773 129 183298 183299 1 133 Convergent + - 0.000000 0 0.000000 0.00000000 1.424470 3.063779 1.0645230 - - - paREP6 1.431733 3.151837 1.0564965 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 5.275852e-05 5.293055e-04 2.606722e-02 1.666265e-02 6.743397e-03 0 0 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180168 0.6447284 U 0.4686274 0.6162291 13773 129 183299 183300 1 -31 Same - - 0.000000 0 0.000000 0.00000000 1.431733 3.151837 1.0564965 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.472807 3.225096 1.0511393 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 1.687093e-03 -4.210036e-04 1.599823e-02 -2.760204e-02 1.496140e-01 0 1 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5128654 0.5933123 U 0.4686274 0.6162291 13773 129 183300 183301 1 960 Divergent - + 0.000000 0 0.000000 0.00000000 1.472807 3.225096 1.0511393 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.411238 3.425581 1.1864999 - - - hypothetical protein 0.000000e+00 0 3.790838e-03 -8.599047e-04 1.361371e-02 -8.841631e-02 3.537648e-01 1 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4957502 0.5241295 U 0.4686274 0.6162291 13773 129 183301 183302 1 85 Same + + 0.000000 0 0.000000 0.00000000 1.411238 3.425581 1.1864999 - - - hypothetical protein 1.523486 3.772369 1.2038313 - - - hypothetical protein 0.000000e+00 0 1.259973e-02 -2.894925e-03 -4.006496e-03 -1.933091e-01 8.867482e-01 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4663742 0.4480717 U 0.4686274 0.6162291 13773 129 183302 183303 1 252 Same + + 0.000000 0 0.000000 0.00000000 1.523486 3.772369 1.2038313 - - - hypothetical protein 1.302226 3.320308 1.1540364 - - - hypothetical protein 0.000000e+00 0 4.895620e-02 -1.075395e-02 -6.169306e-02 -6.029871e-01 2.504312e+00 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3938159 0.4032760 U 0.4686274 0.6162291 13773 129 183303 183304 1 87 Same + + 0.000000 0 0.000000 0.00000000 1.302226 3.320308 1.1540364 - - - hypothetical protein 1.429608 3.136181 1.0841201 - - - paREP2b 0.000000e+00 0 1.622622e-02 3.249630e-03 3.432184e-03 1.143721e-01 6.756007e-01 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5208838 0.4673400 U 0.4686274 0.6162291 13773 129 183304 183305 1 10 Convergent + - 0.000000 0 0.000000 0.00000000 1.429608 3.136181 1.0841201 - - - paREP2b 1.444929 3.237374 1.0567404 - - - paREP8 0.000000e+00 0 2.347324e-04 1.408225e-04 2.128511e-02 -4.094689e-03 2.403333e-02 0 1 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198073 0.6357428 U 0.4686274 0.6162291 13773 129 183305 183306 1 98 Divergent - + 0.000000 0 0.000000 -0.07232066 1.444929 3.237374 1.0567404 - - - paREP8 1.487045 3.168946 1.0695525 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 5.285113e-02 1 1.773779e-03 -2.304607e-04 2.116486e-02 1.438324e-02 1.537988e-01 1 2 FALSE TRUE 106 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.8555544 0.5182143 0.5921731 U 0.4686274 0.5573725 13773 129 183306 183307 1 -24 Same + + 2.856470 0 2.856470 2.78414954 1.487045 3.168946 1.0695525 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.312332 3.025208 1.0115766 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.242508e-01 2 3.052472e-02 -4.957821e-03 8.650586e-03 -3.909627e-01 1.805857e+00 2 2 TRUE TRUE 107 TRUE 2.8950318 1.7172435 0.5480306 2.9213001 0.6838149 1.0601895 0.4214277 0.4107337 U 0.4686274 0.8496451 13773 129 183307 183308 1 60 Convergent + - 0.000000 0 0.000000 0.00000000 1.312332 3.025208 1.0115766 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.393908 3.267075 1.1003879 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 2, authentic frameshift 0.000000e+00 0 6.654642e-03 7.993952e-03 7.348810e-02 4.290023e-01 2.029492e-01 2 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6472706 0.5787234 U 0.4686274 0.6162291 13773 129 183308 183309 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.393908 3.267075 1.1003879 1266 Predicted metal-dependent membrane protease R P. aerophilum family 322 protein part 2, authentic frameshift 1.455060 3.583202 1.1749226 - - - P. aerophilum family 322 protein part 1, authentic frameshift 0.000000e+00 0 3.739657e-03 -2.108313e-04 9.914832e-03 -6.133729e-02 3.583442e-01 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5034887 0.5224252 U 0.4686274 0.6162291 13773 129 183309 183310 1 45 Same - - 0.000000 0 0.000000 0.00000000 1.455060 3.583202 1.1749226 - - - P. aerophilum family 322 protein part 1, authentic frameshift 1.527472 3.552802 1.1477327 - - - conserved within P. aerophilum 0.000000e+00 0 5.243441e-03 2.790264e-04 3.866477e-02 8.691967e-02 2.820482e-01 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176951 0.5503270 U 0.4686274 0.6162291 13773 129 183310 183311 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.527472 3.552802 1.1477327 - - - conserved within P. aerophilum 1.441876 3.510945 1.1687858 - - - hypothetical protein 0.000000e+00 0 7.326644e-03 -7.240177e-04 -2.196519e-03 4.574720e-03 4.295630e-01 0 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195633 0.5075206 U 0.4686274 0.6162291 13773 129 183311 183312 1 25 Same + + 0.000000 0 0.000000 0.00000000 1.441876 3.510945 1.1687858 - - - hypothetical protein 1.440212 3.557289 1.1562086 - - - hypothetical protein 0.000000e+00 0 2.770790e-06 1.064074e-04 2.206933e-02 -5.831045e-05 2.355978e-04 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199722 0.6542630 U 0.4686274 0.6162291 13773 129 183312 183313 1 39 Convergent + - 0.000000 0 0.000000 0.00000000 1.440212 3.557289 1.1562086 - - - hypothetical protein 1.325868 2.868447 0.9780792 82 Chorismate synthase E chorismate synthase (aroC) 0.000000e+00 0 1.307440e-02 1.403515e-03 7.684404e-02 7.437821e-03 7.614337e-01 0 65 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191720 0.4584148 U 0.4686274 0.6162291 13773 129 183313 183314 1 -3 Same - - 4.935912 0 7.598500 4.51827306 1.325868 2.868447 0.9780792 82 Chorismate synthase E chorismate synthase (aroC) 1.384375 2.940641 1.0313219 169 Shikimate 5-dehydrogenase E shikimate 5-dehydrogenase (aroE) 4.384482e-02 21 3.422988e-03 8.412431e-03 9.049071e-02 4.861630e-01 1.083991e-01 E 65 21 FALSE TRUE 106 TRUE 2.8363652 1.7559148 0.5480306 2.8096798 0.7775415 0.8210091 0.6686386 0.6034335 Y 1.4497162 0.9019390 13773 129 183314 183315 1 114 Divergent - + 0.000000 0 0.000000 0.00000000 1.384375 2.940641 1.0313219 169 Shikimate 5-dehydrogenase E shikimate 5-dehydrogenase (aroE) 1.586007 3.523259 1.1270987 - - - hypothetical protein 0.000000e+00 0 4.065550e-02 -9.021582e-03 -5.013306e-02 -4.628713e-01 1.933871e+00 21 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4097574 0.4091482 U 0.4686274 0.6162291 13773 129 183315 183316 1 122 Same + + 0.000000 0 0.000000 0.00000000 1.586007 3.523259 1.1270987 - - - hypothetical protein 1.344161 2.963945 1.0641007 - - - hypothetical protein 0.000000e+00 0 5.848940e-02 -1.443491e-02 -1.648564e-01 -6.817534e-01 2.727694e+00 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3888918 0.4022109 U 0.4686274 0.6162291 13773 129 183316 183317 1 44 Same + + 0.000000 0 0.000000 0.00000000 1.344161 2.963945 1.0641007 - - - hypothetical protein 1.330441 3.159844 1.0971658 345 Pyrroline-5-carboxylate reductase E pyrroline-5-carboxylate reductase 0.000000e+00 0 1.882413e-04 1.296993e-02 1.803362e-01 7.054557e-01 3.053347e-03 0 43 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7549766 0.6486369 U 0.4686274 0.6162291 13773 129 183317 183318 1 -17 Convergent + - 0.000000 0 0.000000 -1.03979529 1.330441 3.159844 1.0971658 345 Pyrroline-5-carboxylate reductase E pyrroline-5-carboxylate reductase 1.447485 3.143884 1.0753571 1051 ADP-ribose pyrophosphatase F mutT/nudix family protein 1.875385e-04 15 1.369931e-02 4.726822e-04 -1.084829e-02 -5.062760e-02 8.580759e-01 0 43 15 TRUE TRUE 108 FALSE 0.4469764 0.2095004 0.5480306 0.4469764 0.7783720 0.4431298 0.5066314 0.4495188 N 0.5492530 0.5373483 13773 129 183318 183319 1 48 Divergent - + 0.000000 0 0.000000 -0.07232066 1.447485 3.143884 1.0753571 1051 ADP-ribose pyrophosphatase F mutT/nudix family protein 1.389154 2.965462 1.0363386 1702 Phosphate starvation-inducible protein PhoH, predicted ATPase T phoH like protein 1.976565e-03 3 3.402456e-03 2.432292e-04 3.337996e-02 -2.958872e-02 3.199235e-01 0 15 3 FALSE TRUE 107 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.7136133 0.4959669 0.5122039 0.5350739 N 0.5492530 0.5660839 13773 129 183319 183320 1 28 Same + + 0.000000 0 0.000000 -0.07232066 1.389154 2.965462 1.0363386 1702 Phosphate starvation-inducible protein PhoH, predicted ATPase T phoH like protein 1.452895 3.158771 1.0731076 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 6.538236e-03 3 4.062892e-03 -9.349689e-05 9.813080e-03 -5.800947e-02 3.864392e-01 3 9 TRUE TRUE 108 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.7136133 0.5642163 0.5044691 0.5147662 U 0.4686274 0.5573725 13773 129 183320 183321 1 58 Convergent + - 0.000000 0 0.000000 -1.48741960 1.452895 3.158771 1.0731076 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.461498 3.167838 1.0859591 451 Nucleoside-diphosphate-sugar epimerases MG UDP-glucose 4-epimerase (galE-1) 1.489667e-02 9 7.400377e-05 1.517974e-05 2.116875e-02 2.229108e-02 6.493663e-03 9 66 TRUE TRUE 109 FALSE 0.4469764 0.2017465 0.5480306 0.4469764 0.7702221 0.6378824 0.5175274 0.6450314 U 0.4686274 0.5260780 13773 129 183321 183322 1 30 Same - - 0.000000 0 0.000000 -12.82859013 1.461498 3.167838 1.0859591 451 Nucleoside-diphosphate-sugar epimerases MG UDP-glucose 4-epimerase (galE-1) 1.454212 3.244911 1.1226307 128 5-enolpyruvylshikimate-3-phosphate synthase E 3-phosphoshikimate 1-carboxyvinyltransferase (aroA) 1.107425e-01 62 5.307847e-05 2.848820e-05 2.083167e-02 2.378713e-02 5.315674e-03 66 62 FALSE TRUE 108 TRUE 0.4469764 0.1765834 0.5480306 0.4469764 0.7708228 1.0467198 0.5174139 0.6461561 U 0.4686274 0.5180786 13773 129 183322 183323 1 -28 Same - - 18.759390 0 27.701125 22.85576950 1.454212 3.244911 1.1226307 128 5-enolpyruvylshikimate-3-phosphate synthase E 3-phosphoshikimate 1-carboxyvinyltransferase (aroA) 1.433181 3.246241 1.1211314 337 3-dehydroquinate synthetase E 3-dehydroquinate synthase 1.814968e-02 27 4.423270e-04 -5.134555e-05 2.095948e-02 -8.990411e-03 3.829936e-02 E 62 27 FALSE TRUE 107 TRUE 2.4200974 1.9340839 0.5480306 2.4850761 0.7761702 0.6635409 0.5188824 0.6286933 Y 1.4497162 0.9239716 13773 129 183323 183324 1 -3 Same - - 7.826284 0 13.302282 12.05565452 1.433181 3.246241 1.1211314 337 3-dehydroquinate synthetase E 3-dehydroquinate synthase 1.349504 2.998439 1.0755541 3958 Transketolase, C-terminal subunit G transketolase (C terminal section) -4.409222e-03 18 7.001834e-03 1.855637e-03 6.795570e-02 5.744816e-02 4.985249e-01 0 27 18 FALSE TRUE 106 TRUE 2.7135479 1.8657252 0.5480306 2.6845552 0.7781393 0.5247710 0.5186591 0.4927282 N 0.5492530 0.8785628 13773 129 183324 183325 1 -6 Same - - 34.423181 0 57.942201 57.82050377 1.349504 2.998439 1.0755541 3958 Transketolase, C-terminal subunit G transketolase (C terminal section) 1.424300 3.079848 1.0708898 3959 Transketolase, N-terminal subunit G transketolase (N terminal section) 4.008490e-01 18 5.594518e-03 2.760459e-03 2.851409e-02 1.406283e-01 3.592636e-01 G 18 19 FALSE TRUE 105 TRUE 2.1452595 2.0478216 0.5480306 2.1662697 0.7781393 1.2469336 0.5278940 0.5214465 Y 1.4497162 0.9356295 13773 129 183325 183326 1 101 Divergent - + 0.000000 0 0.000000 -0.66063515 1.424300 3.079848 1.0708898 3959 Transketolase, N-terminal subunit G transketolase (N terminal section) 1.343986 2.905214 1.0120604 162 Tyrosyl-tRNA synthetase J tyrosyl-tRNA synthetase 2.698094e-02 12 6.450324e-03 2.909941e-03 8.219375e-02 1.467185e-01 4.008843e-01 0 19 12 FALSE TRUE 104 FALSE 0.4469764 0.2264183 0.5480306 0.4469764 0.7776747 0.7209359 0.5294737 0.5124751 N 0.5492530 0.5427026 13773 129 183326 183327 1 171 Same + + 0.000000 0 0.000000 -0.78703061 1.343986 2.905214 1.0120604 162 Tyrosyl-tRNA synthetase J tyrosyl-tRNA synthetase 1.447341 3.192308 1.0972553 2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase E phospho-2-dehydro-3-deoxyheptonate aldolase -2.980329e-02 12 1.068228e-02 4.351603e-04 -3.428864e-03 -4.682506e-02 7.587573e-01 0 12 37 TRUE TRUE 105 TRUE 0.4469764 0.2188849 0.5480306 0.4469764 0.7776747 0.5246769 0.5073958 0.4586701 N 0.5492530 0.5403195 13773 129 183327 183328 1 -3 Convergent + - 0.000000 0 0.000000 -1.26849823 1.447341 3.192308 1.0972553 2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase E phospho-2-dehydro-3-deoxyheptonate aldolase 1.417484 3.280191 1.1335238 2068 Uncharacterized MobA-related protein R conserved protein 9.633797e-03 14 8.914718e-04 1.373832e-04 2.522231e-02 -1.382664e-02 8.866957e-02 37 14 TRUE TRUE 106 FALSE 0.4469764 0.2043655 0.5480306 0.4469764 0.7782928 0.5939425 0.5171720 0.6116373 U 0.4686274 0.5269099 13773 129 183328 183329 1 -18 Same - - 16.314705 0 20.303689 19.28814048 1.417484 3.280191 1.1335238 2068 Uncharacterized MobA-related protein R conserved protein 1.421992 3.084915 1.0955774 1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs C carbon monoxide dehydrogenase large subunit, conjectural 2.057461e-01 14 2.032315e-05 9.969574e-04 3.166960e-02 4.959156e-02 1.140293e-03 14 23 FALSE TRUE 105 TRUE 2.5133856 1.9110896 0.5480306 2.5950686 0.7782928 1.1446908 0.5187781 0.6516922 U 0.4686274 0.8835124 13773 129 183329 183330 1 -3 Same - - 9.173573 0 10.677650 10.31729894 1.421992 3.084915 1.0955774 1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs C carbon monoxide dehydrogenase large subunit, conjectural 1.452800 3.111643 1.0640898 2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs C carbon monoxide dehydrogenase small subunit, conjectural 7.906027e-02 10 9.491624e-04 -4.138338e-05 1.806367e-02 -2.313217e-02 1.014396e-01 C 23 10 FALSE TRUE 104 TRUE 2.6922844 1.8453786 0.5480306 2.7485140 0.7739415 0.9520001 0.5143350 0.6061495 Y 1.4497162 0.9129984 13773 129 183330 183331 1 -3 Same - - 13.915602 0 15.419679 15.36049054 1.452800 3.111643 1.0640898 2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs C carbon monoxide dehydrogenase small subunit, conjectural 1.462820 3.303553 1.1190646 1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs C carbon monoxide dehydrogenase medium subunit, conjectural 1.076066e-01 10 1.003898e-04 1.608415e-05 2.125232e-02 2.321816e-02 9.056378e-03 C 10 14 FALSE TRUE 103 TRUE 2.5913523 1.8800694 0.5480306 2.6706159 0.7739415 1.0353119 0.5174386 0.6434772 Y 1.4497162 0.9173991 13773 129 183331 183332 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.462820 3.303553 1.1190646 1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs C carbon monoxide dehydrogenase medium subunit, conjectural 1.316153 2.924738 1.0230458 287 Prephenate dehydrogenase E chorismate mutase, conjectural 0.000000e+00 0 2.151112e-02 -1.545387e-03 4.878402e-02 -1.871765e-01 1.233242e+00 0 14 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4680465 0.4271864 N 0.5492530 0.6245624 13773 129 183332 183333 1 68 Same - - 0.000000 0 0.000000 0.00000000 1.316153 2.924738 1.0230458 287 Prephenate dehydrogenase E chorismate mutase, conjectural 1.368881 2.950179 1.0056356 - - - paREP5 0.000000e+00 0 2.780171e-03 1.115894e-02 1.220538e-01 6.038176e-01 5.515108e-02 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7209710 0.6221915 U 0.4686274 0.6162291 13773 129 183333 183334 1 47 Same - - 0.000000 0 0.000000 0.00000000 1.368881 2.950179 1.0056356 - - - paREP5 1.473587 3.230653 1.0736542 - - - hypothetical protein 0.000000e+00 0 1.096353e-02 -1.831324e-03 -1.671341e-02 -2.021276e-01 9.425236e-01 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4635213 0.4432769 U 0.4686274 0.6162291 13773 129 183334 183335 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.473587 3.230653 1.0736542 - - - hypothetical protein 1.403994 3.144571 1.1070971 - - - hypothetical protein 0.000000e+00 0 4.843274e-03 -1.052001e-03 1.289189e-02 -1.141754e-01 4.623583e-01 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4869848 0.5012753 U 0.4686274 0.6162291 13773 129 183335 183336 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.403994 3.144571 1.1070971 - - - hypothetical protein 1.342092 3.070925 1.0454422 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 3.831832e-03 5.180762e-03 1.059459e-01 3.097804e-01 1.960933e-01 0 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5961544 0.5808669 U 0.4686274 0.6162291 13773 129 183336 183337 1 63 Same - - 0.000000 0 0.000000 0.00000000 1.342092 3.070925 1.0454422 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.466755 3.429259 1.1229906 2445 Uncharacterized conserved protein S paREP11 0.000000e+00 0 1.554092e-02 -1.679117e-03 -2.863439e-02 -1.951869e-01 1.120056e+00 0 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4658104 0.4318248 U 0.4686274 0.6162291 13773 129 183337 183338 1 114 Same - - 0.000000 0 0.000000 0.00000000 1.466755 3.429259 1.1229906 2445 Uncharacterized conserved protein S paREP11 1.378838 3.049121 1.0213795 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 7.729512e-03 -1.114619e-03 2.047459e-02 -1.407756e-01 6.882759e-01 0 0 FALSE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4794084 0.4656959 U 0.4686274 0.6162291 13773 129 183338 183339 1 13 Same - - 0.000000 0 0.000000 0.00000000 1.378838 3.049121 1.0213795 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.293448 3.092088 1.0480252 - - - hypothetical protein 0.000000e+00 0 7.291336e-03 1.145972e-02 2.047112e-01 5.658269e-01 1.328919e-01 0 0 FALSE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7055552 0.5976378 U 0.4686274 0.6162291 13773 129 183339 183340 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.293448 3.092088 1.0480252 - - - hypothetical protein 1.387150 3.304277 1.0836107 - - - hypothetical protein 0.000000e+00 0 8.779990e-03 1.014684e-02 8.650650e-02 5.071159e-01 1.814250e-01 0 0 FALSE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6753423 0.5847453 U 0.4686274 0.6162291 13773 129 183340 183341 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.387150 3.304277 1.0836107 - - - hypothetical protein 1.412275 3.209849 1.1254023 - - - hypothetical protein 0.000000e+00 0 6.312652e-04 2.513061e-03 4.352614e-02 1.542512e-01 5.733507e-02 0 0 FALSE TRUE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5318676 0.6213153 U 0.4686274 0.6162291 13773 129 183341 183342 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.412275 3.209849 1.1254023 - - - hypothetical protein 1.377640 3.011469 1.0774165 - - - hypothetical protein 0.000000e+00 0 1.199590e-03 2.885078e-03 6.439854e-02 1.759044e-01 9.852757e-02 0 0 FALSE TRUE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5406204 0.6071648 U 0.4686274 0.6162291 13773 129 183342 183343 1 67 Divergent - + 0.000000 0 0.000000 0.00000000 1.377640 3.011469 1.0774165 - - - hypothetical protein 1.355697 3.092286 1.0266367 1100 GTPase SAR1 and related small G proteins R conserved within P. aerophilum 0.000000e+00 0 4.814905e-04 7.057883e-03 1.127028e-01 4.515961e-01 2.015833e-02 0 0 FALSE TRUE 91 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6570601 0.6373715 U 0.4686274 0.6162291 13773 129 183343 183344 1 64 Convergent + - 0.000000 0 0.000000 0.00000000 1.355697 3.092286 1.0266367 1100 GTPase SAR1 and related small G proteins R conserved within P. aerophilum 1.347803 2.998141 1.0292774 1605 Chorismate mutase E 3-dehydroquinate dehydratase (aroD) / possible chorismate mutase (multidomain protein) 0.000000e+00 0 6.231609e-05 9.913160e-03 1.406402e-01 5.925767e-01 2.191648e-03 0 0 TRUE TRUE 92 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7172616 0.6499017 U 0.4686274 0.6162291 13773 129 183344 183345 1 12 Same - - 0.000000 0 0.000000 0.00000000 1.347803 2.998141 1.0292774 1605 Chorismate mutase E 3-dehydroquinate dehydratase (aroD) / possible chorismate mutase (multidomain protein) 1.387474 2.977815 1.0316833 - - - hypothetical protein 0.000000e+00 0 1.573843e-03 6.621312e-03 8.128001e-02 4.159608e-01 7.256470e-02 0 0 FALSE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6422065 0.6171587 U 0.4686274 0.6162291 13773 129 183345 183346 1 14 Divergent - + 0.000000 0 0.000000 0.00000000 1.387474 2.977815 1.0316833 - - - hypothetical protein 1.385555 2.995631 1.0307750 436 Aspartate/tyrosine/aromatic aminotransferase E aspartate aminotransferase (aspC), conjectural 0.000000e+00 0 3.684698e-06 4.208256e-03 7.057433e-02 2.864256e-01 4.953443e-04 0 1 FALSE TRUE 90 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5871701 0.6533218 U 0.4686274 0.6162291 13773 129 183346 183347 1 18 Convergent + - 0.000000 0 0.000000 0.00000000 1.385555 2.995631 1.0307750 436 Aspartate/tyrosine/aromatic aminotransferase E aspartate aminotransferase (aspC), conjectural 1.269091 2.483239 1.1433151 - - - hypothetical protein 0.000000e+00 0 1.356383e-02 1.200238e-02 2.344629e-01 5.351085e-01 1.873568e-01 1 0 TRUE TRUE 91 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6889212 0.5834990 U 0.4686274 0.6162291 13773 129 183347 183348 1 367 Divergent - + 0.000000 0 0.000000 0.00000000 1.269091 2.483239 1.1433151 - - - hypothetical protein 1.417608 3.177083 1.0871699 1685 Archaeal shikimate kinase EH conserved hypothetical protein 0.000000e+00 0 2.205717e-02 6.159113e-03 1.125256e-02 2.337342e-01 5.484863e-01 0 6 FALSE TRUE 90 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5628807 0.4839135 U 0.4686274 0.6162291 13773 129 183348 183349 1 -21 Convergent + - 0.000000 0 0.000000 -0.13150953 1.417608 3.177083 1.0871699 1685 Archaeal shikimate kinase EH conserved hypothetical protein 1.391332 3.007257 1.0597570 1501 Alpha-glucosidases, family 31 of glycosyl hydrolases G alpha-glucosidase 9.602737e-03 6 6.903805e-04 2.029154e-03 5.072506e-02 1.172334e-01 6.375334e-02 6 11 TRUE TRUE 91 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7537284 0.5930262 0.5215979 0.6194066 U 0.4686274 0.5537552 13773 129 183349 183350 1 19 Same - - 0.000000 0 0.000000 0.00000000 1.391332 3.007257 1.0597570 1501 Alpha-glucosidases, family 31 of glycosyl hydrolases G alpha-glucosidase 1.321463 2.835618 0.9666847 4847 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 4.881693e-03 7.803609e-03 1.456902e-01 4.387773e-01 1.617237e-01 11 0 FALSE TRUE 90 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6514649 0.5896102 U 0.4686274 0.6162291 13773 129 183350 183351 1 71 Divergent - + 0.000000 0 0.000000 0.00000000 1.321463 2.835618 0.9666847 4847 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.461788 3.235904 1.1007424 87 Ribosomal protein L3 J ribosomal protein L3 0.000000e+00 0 1.969113e-02 -1.350698e-03 -3.765175e-02 -1.782533e-01 1.194349e+00 0 12 FALSE TRUE 89 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4711743 0.4283385 U 0.4686274 0.6162291 13773 129 183351 183352 1 20 Same + + 27.817261 0 40.873960 40.87395955 1.461788 3.235904 1.1007424 87 Ribosomal protein L3 J ribosomal protein L3 1.392356 3.059263 1.0425174 88 Ribosomal protein L4 J ribosomal protein L4 4.432379e-01 12 4.820836e-03 -6.137226e-04 2.213844e-02 -9.617101e-02 4.644480e-01 J 12 12 TRUE TRUE 90 TRUE 2.1902422 2.0205540 0.5480306 2.2661939 0.7776747 1.2514686 0.4933724 0.5005273 Y 1.4497162 0.9331582 13773 129 183352 183353 1 -3 Same + + 24.598385 0 37.655084 37.65508372 1.392356 3.059263 1.0425174 88 Ribosomal protein L4 J ribosomal protein L4 1.407059 3.059095 1.0607815 89 Ribosomal protein L23 J ribosomal protein L23 2.129022e-01 12 2.161582e-04 2.617347e-03 4.748092e-02 1.627509e-01 2.081742e-02 J 12 18 TRUE TRUE 91 TRUE 2.2492296 2.0086432 0.5480306 2.3151815 0.7776747 1.1509717 0.5355344 0.6371410 Y 1.4497162 0.9317417 13773 129 183353 183354 1 716 Convergent + - 0.000000 0 0.000000 0.00000000 1.407059 3.059095 1.0607815 89 Ribosomal protein L23 J ribosomal protein L23 1.355131 2.946430 1.0129842 - - - hypothetical protein 0.000000e+00 0 2.696487e-03 4.267708e-03 8.917749e-02 2.531969e-01 1.698477e-01 18 0 TRUE TRUE 92 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5709825 0.5877478 U 0.4686274 0.6162291 13773 129 183354 183355 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.355131 2.946430 1.0129842 - - - hypothetical protein 1.442374 3.079690 1.0519854 1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) J conserved protein (RNA polymerase related?) 0.000000e+00 0 7.611380e-03 8.681660e-04 7.563052e-03 -8.056265e-03 5.784402e-01 0 4 FALSE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191732 0.4799478 U 0.4686274 0.6162291 13773 129 183355 183356 1 57 Divergent - + 0.000000 0 0.000000 0.00000000 1.442374 3.079690 1.0519854 1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) J conserved protein (RNA polymerase related?) 1.572427 3.594624 1.1483798 3286 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.691385e-02 -1.091583e-03 4.497017e-02 8.682956e-03 6.358318e-01 4 0 FALSE TRUE 90 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190059 0.4717106 U 0.4686274 0.6162291 13773 129 183356 183357 1 103 Same + + 0.000000 0 0.000000 0.00000000 1.572427 3.594624 1.1483798 3286 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.628920 3.608032 1.0894302 1761 DNA-directed RNA polymerase, subunit L K DNA-directed RNA polymerase subunit L (rpoL) 0.000000e+00 0 3.191382e-03 2.148686e-02 3.148005e-01 7.318491e-01 9.499891e-03 0 3 TRUE TRUE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7621592 0.6431205 U 0.4686274 0.6162291 13773 129 183357 183358 1 -3 Same + + 0.000000 0 0.000000 -0.37231642 1.628920 3.608032 1.0894302 1761 DNA-directed RNA polymerase, subunit L K DNA-directed RNA polymerase subunit L (rpoL) 1.459890 3.271505 1.0598707 1756 Uncharacterized conserved protein S conserved hypothetical protein 9.813788e-02 3 2.857090e-02 1.508537e-03 -4.147526e-02 1.647182e-01 5.237627e-01 3 8 TRUE TRUE 92 TRUE 0.4469764 0.2462769 0.5480306 0.4469764 0.7136133 1.0055065 0.5363646 0.4888416 U 0.4686274 0.5401990 13773 129 183358 183359 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.459890 3.271505 1.0598707 1756 Uncharacterized conserved protein S conserved hypothetical protein 1.520250 3.311515 1.1189637 - - - hypothetical protein 0.000000e+00 0 3.643301e-03 5.851158e-04 3.943629e-02 1.133484e-01 1.947363e-01 8 0 TRUE TRUE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5204559 0.5814495 U 0.4686274 0.6162291 13773 129 183359 183360 1 41 Same + + 0.000000 0 0.000000 0.00000000 1.520250 3.311515 1.1189637 - - - hypothetical protein 1.489281 3.132496 1.0144296 1404 Subtilisin-like serine proteases O aerolysin, part 1, authentic frameshift 0.000000e+00 0 9.590984e-04 2.608862e-03 4.284606e-02 2.726102e-01 3.449387e-02 0 0 TRUE TRUE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5816210 0.6302077 U 0.4686274 0.6162291 13773 129 183360 183361 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.489281 3.132496 1.0144296 1404 Subtilisin-like serine proteases O aerolysin, part 1, authentic frameshift 1.473424 3.340580 1.1124382 1404 Subtilisin-like serine proteases O aerolysin, part 2, authentic frameshift 0.000000e+00 0 2.514311e-04 8.347243e-04 2.808469e-02 1.312692e-01 1.887197e-02 O 0 0 TRUE TRUE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5246621 0.6382319 Y 1.4497162 0.7118045 13773 129 183361 183362 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.473424 3.340580 1.1124382 1404 Subtilisin-like serine proteases O aerolysin, part 2, authentic frameshift 1.432431 3.044025 1.0582203 65 3-isopropylmalate dehydratase large subunit E 3-isopropylmalate dehydratase large subunit (leuC) 0.000000e+00 0 1.680441e-03 -4.177546e-04 1.553363e-02 -2.579324e-02 1.490209e-01 0 0 43 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5136638 0.5934994 N 0.5492530 0.6245624 13773 129 183362 183363 1 10 Convergent + - 0.000000 0 0.000000 -7.08527530 1.432431 3.044025 1.0582203 65 3-isopropylmalate dehydratase large subunit E 3-isopropylmalate dehydratase large subunit (leuC) 1.396797 3.062799 1.0847578 78 Ornithine carbamoyltransferase E ornithine carbamoyltransferase (argF) 1.099180e-01 43 1.269777e-03 1.035233e-03 3.949834e-02 3.892075e-02 1.345758e-01 E 43 59 TRUE TRUE 97 FALSE 0.4469764 0.1795239 0.5480306 0.4469764 0.7726613 1.0448097 0.5181027 0.5971986 Y 1.4497162 0.6240288 13773 129 183363 183364 1 46 Same - - 0.000000 0 0.000000 -0.29856362 1.396797 3.062799 1.0847578 78 Ornithine carbamoyltransferase E ornithine carbamoyltransferase (argF) 1.418096 3.020204 1.0333797 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) with possible unusual start codon 9.399069e-03 3 4.536417e-04 1.817867e-03 3.723870e-02 1.063370e-01 4.750593e-02 E 59 3 FALSE TRUE 96 TRUE 0.4469764 0.2552514 0.5480306 0.4469764 0.7136133 0.5898397 0.5194917 0.6249782 Y 1.4497162 0.6463811 13773 129 183364 183365 1 155 Divergent - + 0.000000 0 0.000000 0.00000000 1.418096 3.020204 1.0333797 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) with possible unusual start codon 1.458473 3.153247 1.0850293 5270 PUA domain (predicted RNA-binding domain) J conserved hypothetical protein 2.301138e-03 3 1.630269e-03 -2.357328e-04 1.529322e-02 -3.766855e-02 1.562160e-01 0 3 4 FALSE TRUE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5002879 0.5096263 0.5909581 N 0.5492530 0.6245624 13773 129 183365 183366 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.458473 3.153247 1.0850293 5270 PUA domain (predicted RNA-binding domain) J conserved hypothetical protein 1.446318 3.195453 1.0635771 1913 Predicted Zn-dependent proteases R conserved hypothetical protein 0.000000e+00 0 1.477301e-04 -3.592748e-05 2.025573e-02 7.016690e-03 1.360813e-02 4 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192720 0.6412444 U 0.4686274 0.6162291 13773 129 183366 183367 1 -17 Convergent + - 0.000000 0 0.000000 0.00000000 1.446318 3.195453 1.0635771 1913 Predicted Zn-dependent proteases R conserved hypothetical protein 1.483172 3.264785 1.0878269 66 3-isopropylmalate dehydratase small subunit E 3-isopropylmalate dehydratase small subunit (leuD) 0.000000e+00 0 1.358207e-03 -1.612696e-04 2.135137e-02 1.712207e-02 1.208670e-01 0 14 TRUE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179242 0.6007310 U 0.4686274 0.6162291 13773 129 183367 183368 1 149 Divergent - + 1.504077 0 1.504077 1.30802934 1.483172 3.264785 1.0878269 66 3-isopropylmalate dehydratase small subunit E 3-isopropylmalate dehydratase small subunit (leuD) 1.408013 3.027470 1.0769523 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) with possible unusual start codon 3.889664e-02 7 5.648848e-03 -1.378569e-03 6.833218e-03 -1.291665e-01 5.204355e-01 E 14 7 FALSE TRUE 96 FALSE 2.9322497 1.6400368 0.5480306 2.9467151 0.7596462 0.7986660 0.4819832 0.4892985 Y 1.4497162 0.8868967 13773 129 183368 183369 1 94 Same + + 2.197225 0 2.197225 1.87601338 1.408013 3.027470 1.0769523 119 Isopropylmalate/homocitrate/citramalate synthases E 2-isopropylmalate synthase (leuA) with possible unusual start codon 1.475207 3.088807 1.0779513 473 Isocitrate/isopropylmalate dehydrogenase CE 3-isopropylmalate dehydrogenase (leuB) 2.013797e-02 7 4.514969e-03 -1.033037e-03 5.320451e-03 -1.056126e-01 4.225499e-01 7 42 TRUE TRUE 97 TRUE 2.9321590 1.6474476 0.5480306 2.9469979 0.7596462 0.6815325 0.4893097 0.5083822 U 0.4686274 0.8373020 13773 129 183369 183370 1 54 Same + + 0.000000 0 0.000000 -1.36015756 1.475207 3.088807 1.0779513 473 Isocitrate/isopropylmalate dehydrogenase CE 3-isopropylmalate dehydrogenase (leuB) 1.419463 3.043843 1.0649524 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 3.954409e-03 12 3.107391e-03 -7.603794e-04 1.299608e-02 -7.220954e-02 2.977490e-01 42 12 TRUE TRUE 98 TRUE 0.4469764 0.2038444 0.5480306 0.4469764 0.7776747 0.5351157 0.5006836 0.5430248 U 0.4686274 0.5267444 13773 129 183370 183371 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.419463 3.043843 1.0649524 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 1.419355 3.099195 1.0019751 - - - hypothetical protein 0.000000e+00 0 1.168540e-08 1.022984e-03 3.271626e-02 5.125665e-02 2.355978e-06 12 0 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187855 0.6559187 U 0.4686274 0.6162291 13773 129 183371 183372 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.419355 3.099195 1.0019751 - - - hypothetical protein 1.397746 2.983806 1.0393278 4900 Predicted metallopeptidase R conserved hypothetical protein 0.000000e+00 0 4.669537e-04 1.718764e-03 4.553609e-02 1.004212e-01 4.617716e-02 0 1 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187636 0.6255200 U 0.4686274 0.6162291 13773 129 183372 183373 1 59 Divergent - + 0.000000 0 0.000000 0.00000000 1.397746 2.983806 1.0393278 4900 Predicted metallopeptidase R conserved hypothetical protein 1.405389 3.234286 1.0995264 765 ABC-type amino acid transport system, permease component E glutamine transport system permease protein, putative 5.071901e-03 1 5.841659e-05 2.468005e-03 4.766009e-02 1.591133e-01 6.743397e-03 1 23 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5434219 0.5342321 0.6447284 U 0.4686274 0.6162291 13773 129 183373 183374 1 3 Same + + 20.495439 0 35.357325 33.07915474 1.405389 3.234286 1.0995264 765 ABC-type amino acid transport system, permease component E glutamine transport system permease protein, putative 1.444836 3.275088 1.1419804 1126 ABC-type polar amino acid transport system, ATPase component E glutamine transport ATP-binding 1.453558e-01 23 1.556131e-03 3.016236e-04 1.899893e-02 -1.187825e-02 1.544013e-01 E 23 51 TRUE TRUE 98 TRUE 2.3730407 1.9935606 0.5480306 2.3371131 0.7771174 1.0856663 0.5180339 0.5918248 Y 1.4497162 0.9295102 13773 129 183374 183375 1 23 Same + + 0.000000 0 0.000000 -1.53043985 1.444836 3.275088 1.1419804 1126 ABC-type polar amino acid transport system, ATPase component E glutamine transport ATP-binding 1.389002 2.968571 1.0495022 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase 7.758740e-03 15 3.117525e-03 4.090637e-04 3.529687e-02 -1.676631e-02 2.927449e-01 0 51 15 TRUE TRUE 99 TRUE 0.4469764 0.2012185 0.5480306 0.4469764 0.7783720 0.5778415 0.5163266 0.5451177 N 0.5492530 0.5347240 13773 129 183375 183376 1 28 Same + + 0.000000 0 0.000000 -0.95890868 1.389002 2.968571 1.0495022 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase 1.406020 2.958161 1.0205356 84 Mg-dependent DNase L conserved hypothetical protein -4.410233e-02 15 2.896148e-04 2.830887e-03 4.917990e-02 1.785807e-01 2.451159e-02 0 15 51 TRUE TRUE 100 TRUE 0.4469764 0.2125161 0.5480306 0.4469764 0.7783720 0.5246345 0.5419359 0.6356211 N 0.5492530 0.5383034 13773 129 183376 183377 1 -12 Same + + 0.000000 0 0.000000 -0.34959831 1.406020 2.958161 1.0205356 84 Mg-dependent DNase L conserved hypothetical protein 1.375240 2.974991 1.0365255 639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases T serine/threonine specific protein phosphatase 2.241257e-03 5 9.473774e-04 3.455287e-03 7.063691e-02 2.212027e-01 7.718418e-02 0 51 5 TRUE TRUE 101 TRUE 0.4469764 0.2482804 0.5480306 0.4469764 0.7448207 0.4990423 0.5578490 0.6158124 N 0.5492530 0.5496068 13773 129 183377 183378 1 226 Same + + 0.000000 0 0.000000 0.00000000 1.375240 2.974991 1.0365255 639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases T serine/threonine specific protein phosphatase 1.458630 3.303181 1.1568755 - - - P. aerophilum family 59 protein 0.000000e+00 0 6.953781e-03 -5.510922e-04 -3.000305e-04 -1.019078e-01 6.260781e-01 5 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4903462 0.4737580 U 0.4686274 0.6162291 13773 129 183378 183379 1 1 Same + + 0.000000 0 0.000000 0.00000000 1.458630 3.303181 1.1568755 - - - P. aerophilum family 59 protein 1.514704 3.665746 1.1543802 - - - P. aerophilum family 3 protein 0.000000e+00 0 3.144362e-03 4.581633e-04 3.614083e-02 9.581820e-02 1.847086e-01 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180994 0.5840258 U 0.4686274 0.6162291 13773 129 183379 183380 1 38 Convergent + - 0.000000 0 0.000000 0.00000000 1.514704 3.665746 1.1543802 - - - P. aerophilum family 3 protein 1.383919 3.010483 1.0000735 717 Deoxycytidine deaminase F deoxycytidine triphosphate deaminase 0.000000e+00 0 1.710483e-02 -4.271875e-03 -2.782765e-02 -3.292331e-01 1.318179e+00 0 31 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4328030 0.4234192 U 0.4686274 0.6162291 13773 129 183380 183381 1 93 Divergent - + 0.000000 0 0.000000 0.00000000 1.383919 3.010483 1.0000735 717 Deoxycytidine deaminase F deoxycytidine triphosphate deaminase 1.338977 3.047865 1.0755187 - - - hypothetical protein 0.000000e+00 0 2.019749e-03 7.585157e-03 1.299562e-01 4.663069e-01 7.933107e-02 31 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6627836 0.6149078 U 0.4686274 0.6162291 13773 129 183381 183382 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.338977 3.047865 1.0755187 - - - hypothetical protein 1.559866 3.593062 1.1452187 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 0.000000e+00 0 4.879208e-02 -1.219413e-02 -1.240509e-01 -6.515433e-01 2.609849e+00 0 1 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3898340 0.4027255 U 0.4686274 0.6162291 13773 129 183382 183383 1 43 Divergent - + 0.000000 0 0.000000 0.00000000 1.559866 3.593062 1.1452187 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 1.347212 3.054050 1.0514460 350 Methylated DNA-protein cysteine methyltransferase L methylated-DNA--[protein]-cysteine S-methyltransferase (ogt) 0.000000e+00 0 4.522204e-02 -1.130090e-02 -1.137137e-01 -6.205174e-01 2.482499e+00 0 1 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3926486 0.4035174 N 0.5492530 0.6245624 13773 129 183383 183384 1 37 Same + + 0.000000 0 0.000000 0.00000000 1.347212 3.054050 1.0514460 350 Methylated DNA-protein cysteine methyltransferase L methylated-DNA--[protein]-cysteine S-methyltransferase (ogt) 1.356222 2.723797 0.9973212 1141 Ferredoxin C ferredoxin 0.000000e+00 0 8.119344e-05 9.914976e-03 1.321046e-01 5.941776e-01 2.886073e-03 0 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7180828 0.6487603 N 0.5492530 0.6245624 13773 129 183384 183385 1 197 Same + + 0.000000 0 0.000000 0.00000000 1.356222 2.723797 0.9973212 1141 Ferredoxin C ferredoxin 1.404118 3.429374 1.1115850 - - - conserved within P. aerophilum 0.000000e+00 0 2.293946e-03 4.499215e-03 5.601806e-02 2.790921e-01 1.365538e-01 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5840161 0.5967244 U 0.4686274 0.6162291 13773 129 183385 183386 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.404118 3.429374 1.1115850 - - - conserved within P. aerophilum 1.368379 3.034855 1.0418102 560 Phosphoserine phosphatase E phosphoserine phosphatase (serB) 0.000000e+00 0 1.277270e-03 3.924525e-03 7.844932e-02 2.526215e-01 8.935649e-02 0 4 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5703459 0.6112026 U 0.4686274 0.6162291 13773 129 183386 183387 1 82 Same + + 0.000000 0 0.000000 0.00000000 1.368379 3.034855 1.0418102 560 Phosphoserine phosphatase E phosphoserine phosphatase (serB) 1.386117 2.965008 1.0348200 704 Phosphate uptake regulator P conserved hypothetical protein 0.000000e+00 0 3.146414e-04 5.418846e-03 7.741645e-02 3.635474e-01 1.803795e-02 0 4 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6170084 0.6386975 N 0.5492530 0.6245624 13773 129 183387 183388 1 -15 Same + + 0.000000 0 0.000000 0.00000000 1.386117 2.965008 1.0348200 704 Phosphate uptake regulator P conserved hypothetical protein 1.443578 3.473261 1.1574482 4089 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 3.301758e-03 5.101445e-04 1.603678e-02 -1.200783e-02 3.155973e-01 0 4 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179784 0.5371275 U 0.4686274 0.6162291 13773 129 183388 183389 1 238 Convergent + - 0.000000 0 0.000000 -0.24929257 1.443578 3.473261 1.1574482 4089 Predicted membrane protein S conserved hypothetical protein 1.463064 3.166614 1.0485768 1731 Archaeal riboflavin synthase H conserved hypothetical protein 6.304986e-02 4 3.797261e-04 -9.121395e-05 1.986202e-02 4.645988e-03 3.477953e-02 4 9 TRUE TRUE 109 FALSE 0.4469764 0.2655387 0.5480306 0.4469764 0.7323301 0.8982713 0.5195297 0.6300598 U 0.4686274 0.5462885 13773 129 183389 183390 1 46 Divergent - + 0.000000 0 0.000000 -0.35132529 1.463064 3.166614 1.0485768 1731 Archaeal riboflavin synthase H conserved hypothetical protein 1.406282 3.024056 1.0717720 864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-bin K conserved (helix-turn-helix protein, copG family) 9.393202e-02 5 3.224224e-03 -5.265062e-04 1.940357e-02 -7.257353e-02 3.095902e-01 0 9 5 FALSE TRUE 108 FALSE 0.4469764 0.2478821 0.5480306 0.4469764 0.7448207 0.9882295 0.5005995 0.5385067 N 0.5492530 0.5494812 13773 129 183390 183391 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.406282 3.024056 1.0717720 864 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-bin K conserved (helix-turn-helix protein, copG family) 1.370992 2.920691 0.9731549 1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily R conserved hypothetical protein 9.520652e-04 1 1.245368e-03 3.626942e-03 7.439309e-02 2.275927e-01 9.423910e-02 5 1 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.5607909 0.6091015 U 0.4686274 0.6162291 13773 129 183391 183392 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.370992 2.920691 0.9731549 1310 Predicted metal-dependent protease of the PAD1/JAB1 superfamily R conserved hypothetical protein 1.435646 3.057442 1.0886317 6 Xaa-Pro aminopeptidase E xaa-Pro dipeptidase, putative 3.796057e-03 1 4.180082e-03 1.266076e-03 1.975467e-02 3.667609e-02 3.583442e-01 1 18 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5336363 0.5178065 0.5224252 U 0.4686274 0.6162291 13773 129 183392 183393 1 1 Convergent + - 0.000000 0 0.000000 0.00000000 1.435646 3.057442 1.0886317 6 Xaa-Pro aminopeptidase E xaa-Pro dipeptidase, putative 1.721545 3.899473 1.0741477 - - - paREP10, authentic frameshift 0.000000e+00 0 8.173846e-02 -4.254111e-03 1.557068e-01 -5.477766e-02 1.068677e+00 18 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5054217 0.4347792 U 0.4686274 0.6162291 13773 129 183393 183394 1 206 Same - - 0.000000 0 0.000000 0.00000000 1.721545 3.899473 1.0741477 - - - paREP10, authentic frameshift 1.406225 2.998161 1.0544583 146 N-methylhydantoinase B/acetone carboxylase, alpha subunit EQ N-methylhydantoinase B (hyuB) 0.000000e+00 0 9.942673e-02 -1.220217e-02 -3.020917e-01 -3.406720e-01 1.758728e+00 0 9 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4296366 0.4112734 U 0.4686274 0.6162291 13773 129 183394 183395 1 -3 Same - - 15.017267 0 17.679854 17.56793642 1.406225 2.998161 1.0544583 146 N-methylhydantoinase B/acetone carboxylase, alpha subunit EQ N-methylhydantoinase B (hyuB) 1.413974 3.118541 1.1080036 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ N-methylhydantoinase A (hyuA) 2.468383e-01 9 6.004228e-05 1.690134e-03 3.887407e-02 9.439342e-02 6.008332e-03 9 14 FALSE TRUE 109 TRUE 2.5699604 1.8944974 0.5480306 2.6415732 0.7702221 1.1828738 0.5179966 0.6454790 U 0.4686274 0.8805833 13773 129 183395 183396 1 166 Divergent - + 0.000000 0 0.000000 -0.05129329 1.413974 3.118541 1.1080036 145 N-methylhydantoinase A/acetone carboxylase, beta subunit EQ N-methylhydantoinase A (hyuA) 1.541617 3.346999 1.0358618 4274 Uncharacterized conserved protein S conserved hypothetical protein 6.432019e-04 4 1.629271e-02 -3.376091e-03 -1.619811e-03 -1.952322e-01 9.831872e-01 14 4 FALSE TRUE 108 FALSE 0.4469764 0.3080876 0.5480306 0.4469764 0.7323301 0.4592152 0.4656689 0.4410068 U 0.4686274 0.5596885 13773 129 183396 183397 1 184 Convergent + - 0.000000 0 0.000000 0.00000000 1.541617 3.346999 1.0358618 4274 Uncharacterized conserved protein S conserved hypothetical protein 1.464333 3.346039 1.0930764 2445 Uncharacterized conserved protein S paREP11 7.562104e-04 1 5.972818e-03 1.167483e-03 1.414096e-02 1.554115e-01 2.550134e-01 4 1 TRUE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5324045 0.5607931 U 0.4686274 0.6162291 13773 129 183397 183398 1 154 Same - - 0.000000 0 0.000000 0.00000000 1.464333 3.346039 1.0930764 2445 Uncharacterized conserved protein S paREP11 1.545768 3.705843 1.1271366 1708 Predicted nucleotidyltransferases R hypothetical protein 0.000000e+00 0 6.631723e-03 1.221201e-03 5.720971e-02 1.573976e-01 2.643996e-01 1 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5334844 0.5555494 U 0.4686274 0.6162291 13773 129 183398 183399 1 267 Divergent - + 0.000000 0 0.000000 0.00000000 1.545768 3.705843 1.1271366 1708 Predicted nucleotidyltransferases R hypothetical protein 1.392746 3.094628 1.0854128 277 FAD/FMN-containing dehydrogenases C D-lactate dehydrogenase 0.000000e+00 0 2.341571e-02 -5.534795e-03 -5.786082e-02 -3.467227e-01 1.451812e+00 0 16 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4286329 0.4183522 U 0.4686274 0.6162291 13773 129 183399 183400 1 -22 Convergent + - 0.000000 0 0.000000 0.00000000 1.392746 3.094628 1.0854128 277 FAD/FMN-containing dehydrogenases C D-lactate dehydrogenase 1.497786 3.932899 1.2853988 - - - hypothetical protein 0.000000e+00 0 1.103338e-02 -2.720809e-03 -1.434338e-02 -2.340652e-01 9.365724e-01 16 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4559943 0.4438946 U 0.4686274 0.6162291 13773 129 183400 183401 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.497786 3.932899 1.2853988 - - - hypothetical protein 1.417115 3.198279 1.0976221 1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) R hypothetical protein 0.000000e+00 0 6.507864e-03 -1.590272e-03 -3.381876e-04 -1.210030e-01 5.450813e-01 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4846254 0.4841397 U 0.4686274 0.6162291 13773 129 183401 183402 1 38 Divergent - + 0.000000 0 0.000000 0.00000000 1.417115 3.198279 1.0976221 1721 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) R hypothetical protein 1.357269 2.975451 1.0518900 714 MoxR-like ATPases R moxR related protein 0.000000e+00 0 3.581461e-03 3.226372e-03 7.797550e-02 1.809391e-01 2.412521e-01 0 34 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5425270 0.5655296 U 0.4686274 0.6162291 13773 129 183402 183403 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.357269 2.975451 1.0518900 714 MoxR-like ATPases R moxR related protein 1.436563 3.395023 1.1588006 - - - hypothetical protein 0.000000e+00 0 6.287420e-03 1.395865e-03 1.511900e-02 3.449151e-02 4.760259e-01 34 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175355 0.4973638 U 0.4686274 0.6162291 13773 129 183403 183404 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.436563 3.395023 1.1588006 - - - hypothetical protein 1.420402 3.236499 1.1068495 1305 Transglutaminase-like enzymes, putative cysteine proteases E hypothetical protein 0.000000e+00 0 2.611708e-04 4.596005e-04 2.799199e-02 1.009595e-02 2.850733e-02 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5188994 0.6338085 U 0.4686274 0.6162291 13773 129 183404 183405 1 329 Same - - 0.000000 0 0.000000 0.00000000 1.420402 3.236499 1.1068495 1305 Transglutaminase-like enzymes, putative cysteine proteases E hypothetical protein 1.258337 2.829338 0.9616667 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 2.626501e-02 5.982979e-03 1.829022e-01 2.120150e-01 5.889944e-01 0 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5539805 0.4782490 N 0.5492530 0.6245624 13773 129 183405 183406 1 43 Same - - 0.000000 0 0.000000 0.00000000 1.258337 2.829338 0.9616667 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.271709 2.844343 0.9772384 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 1.788000e-04 3.468906e-02 4.136747e-01 9.604808e-01 3.769564e-05 0 0 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8133759 0.6555210 N 0.5492530 0.6245624 13773 129 183406 183407 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.271709 2.844343 0.9772384 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.379731 3.038713 1.0029933 - - - P. aerophilum family 453 0.000000e+00 0 1.166888e-02 1.287645e-02 1.023425e-01 5.720897e-01 1.531974e-01 0 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7087464 0.5924418 U 0.4686274 0.6162291 13773 129 183407 183408 1 199 Divergent - + 0.000000 0 0.000000 0.00000000 1.379731 3.038713 1.0029933 - - - P. aerophilum family 453 1.476817 3.223918 1.0423908 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 9.425664e-03 -1.821945e-03 -1.196482e-02 -1.954902e-01 8.453271e-01 0 0 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4653853 0.4510979 U 0.4686274 0.6162291 13773 129 183408 183409 1 251 Same + + 0.000000 0 0.000000 0.00000000 1.476817 3.223918 1.0423908 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.403713 2.967773 1.0008978 1831 Predicted metal-dependent hydrolase (urease superfamily) R conserved hypothetical protein 0.000000e+00 0 5.344226e-03 -1.212228e-03 1.069571e-02 -1.268252e-01 5.094213e-01 0 10 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4828296 0.4915849 U 0.4686274 0.6162291 13773 129 183409 183410 1 829 Convergent + - 0.000000 0 0.000000 -0.13353139 1.403713 2.967773 1.0008978 1831 Predicted metal-dependent hydrolase (urease superfamily) R conserved hypothetical protein 1.783896 3.804624 1.0039692 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 2.713081e-03 4 1.445393e-01 -1.585373e-02 1.103625e-01 -3.752277e-01 1.870366e+00 10 4 TRUE TRUE 104 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.7323301 0.5086020 0.4239323 0.4100105 U 0.4686274 0.5517368 13773 129 183410 183411 1 83 Divergent - + 0.000000 0 0.000000 -0.13353139 1.783896 3.804624 1.0039692 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.414478 3.100956 1.0668300 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 4.118834e-02 1 1.364697e-01 -1.227424e-02 -4.000799e-01 -2.622804e-01 1.570665e+00 4 1 FALSE TRUE 103 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.8108260 0.4490156 0.4150690 U 0.4686274 0.5517368 13773 129 183411 183412 1 -11 Convergent + - 0.000000 0 0.000000 0.00000000 1.414478 3.100956 1.0668300 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 1.307951 2.848233 1.0106608 399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogen M pleiotropic regulatory protein, conjectural 9.094140e-03 1 1.134811e-02 5.295114e-03 1.314411e-01 2.465884e-01 4.396820e-01 0 1 36 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5875828 0.5680532 0.5054889 N 0.5492530 0.6245624 13773 129 183412 183413 1 30 Divergent - + 0.000000 0 0.000000 0.00000000 1.307951 2.848233 1.0106608 399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogen M pleiotropic regulatory protein, conjectural 1.295257 3.118622 1.0797144 - - - hypothetical protein 0.000000e+00 0 1.611412e-04 2.239653e-02 2.922616e-01 8.872906e-01 7.215181e-04 36 0 FALSE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8022633 0.6523872 U 0.4686274 0.6162291 13773 129 183413 183414 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.295257 3.118622 1.0797144 - - - hypothetical protein 1.387198 2.847961 0.9837337 2151 Predicted metal-sulfur cluster biosynthetic enzyme R conserved hypothetical protein 0.000000e+00 0 8.453174e-03 1.002319e-02 8.648751e-02 5.059756e-01 1.814250e-01 0 12 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6746285 0.5847453 U 0.4686274 0.6162291 13773 129 183414 183415 1 80 Divergent - + 0.000000 0 0.000000 -0.07232066 1.387198 2.847961 0.9837337 2151 Predicted metal-sulfur cluster biosynthetic enzyme R conserved hypothetical protein 1.285413 2.779966 1.0089518 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 2.507089e-02 1 1.036016e-02 1.065511e-02 2.048168e-01 5.128845e-01 1.927095e-01 12 1 FALSE TRUE 103 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.7074534 0.6789429 0.5822442 U 0.4686274 0.5573725 13773 129 183415 183416 1 1 Convergent + - 0.000000 0 0.000000 0.00000000 1.285413 2.779966 1.0089518 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 1.359422 2.927227 1.1222951 - - - paREP6 part 2, authentic frameshift 0.000000e+00 0 5.477295e-03 1.526540e-02 1.507441e-01 7.024288e-01 5.918746e-02 1 0 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7527514 0.6207976 U 0.4686274 0.6162291 13773 129 183416 183417 1 22 Same - - 0.000000 0 0.000000 0.00000000 1.359422 2.927227 1.1222951 - - - paREP6 part 2, authentic frameshift 1.459142 2.758232 1.0981252 - - - paREP6 part 1, authentic frameshift 0.000000e+00 0 9.944109e-03 -7.126732e-04 -8.923590e-03 -1.241217e-01 8.035203e-01 0 0 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4839099 0.4550988 U 0.4686274 0.6162291 13773 129 183417 183418 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.459142 2.758232 1.0981252 - - - paREP6 part 1, authentic frameshift 1.314007 2.782452 0.9558664 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R conserved hypothetical protein 0.000000e+00 0 2.106404e-02 -1.064583e-03 5.607059e-02 -1.557761e-01 1.169319e+00 0 3 FALSE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4754993 0.4297294 U 0.4686274 0.6162291 13773 129 183418 183419 1 -62 Convergent + - 0.000000 0 0.000000 0.00000000 1.314007 2.782452 0.9558664 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R conserved hypothetical protein 1.426612 3.165999 1.0999589 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R conserved hypothetical protein 0.000000e+00 0 1.267975e-02 3.404597e-03 1.417194e-02 1.404080e-01 5.714571e-01 3 0 TRUE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5276318 0.4812875 U 0.4686274 0.6162291 13773 129 183419 183420 1 57 Same - - 0.000000 0 0.000000 0.00000000 1.426612 3.165999 1.0999589 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R conserved hypothetical protein 1.368517 2.886911 1.0034480 - - - conserved within P. aerophilum, part 2, authentic frameshift 0.000000e+00 0 3.375019e-03 2.053781e-03 6.063406e-02 1.037078e-01 2.683606e-01 0 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191457 0.5545399 U 0.4686274 0.6162291 13773 129 183420 183421 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.368517 2.886911 1.0034480 - - - conserved within P. aerophilum, part 2, authentic frameshift 1.483660 3.510503 1.0974938 - - - conserved within P. aerophilum, part 1, authentic frameshift 0.000000e+00 0 1.325798e-02 -2.674175e-03 -2.532800e-02 -2.657189e-01 1.139634e+00 0 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4485097 0.4309702 U 0.4686274 0.6162291 13773 129 183421 183422 1 574 Same - - 0.000000 0 0.000000 0.00000000 1.483660 3.510503 1.0974938 - - - conserved within P. aerophilum, part 1, authentic frameshift 1.407760 3.095806 1.0538532 - - - paREP2b 0.000000e+00 0 5.760843e-03 -1.407914e-03 6.466758e-03 -1.310395e-01 5.282155e-01 0 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4814969 0.4879284 U 0.4686274 0.6162291 13773 129 183422 183423 1 34 Same - - 0.000000 0 0.000000 0.00000000 1.407760 3.095806 1.0538532 - - - paREP2b 1.568171 3.543249 1.1725686 - - - paREP2b 0.000000e+00 0 2.573167e-02 -5.095382e-03 -9.042345e-03 -2.648779e-01 1.277958e+00 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4486786 0.4250355 U 0.4686274 0.6162291 13773 129 183423 183424 1 559 Same - - 0.000000 0 0.000000 0.00000000 1.568171 3.543249 1.1725686 - - - paREP2b 1.329349 2.912124 0.9841845 - - - hypothetical protein 0.000000e+00 0 5.703588e-02 -1.425204e-02 -1.427072e-01 -6.953044e-01 2.786312e+00 0 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3877115 0.4020054 U 0.4686274 0.6162291 13773 129 183424 183425 1 26 Divergent - + 0.000000 0 0.000000 0.00000000 1.329349 2.912124 0.9841845 - - - hypothetical protein 1.311254 2.900915 0.9977396 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 0.000000e+00 0 3.274112e-04 1.710307e-02 2.327592e-01 8.015036e-01 2.565660e-03 0 3 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7865917 0.6491703 U 0.4686274 0.6162291 13773 129 183425 183426 1 48 Same + + 0.000000 0 0.000000 -0.13353139 1.311254 2.900915 0.9977396 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 1.378930 3.087426 1.0837209 503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins F phosphoribosyl transferase 1.351416e-02 3 4.579999e-03 1.015484e-02 1.029326e-01 5.428172e-01 1.099205e-01 0 3 5 TRUE TRUE 98 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.7136133 0.6296779 0.6942389 0.6030494 N 0.5492530 0.5604716 13773 129 183426 183427 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.378930 3.087426 1.0837209 503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins F phosphoribosyl transferase 1.404683 3.191561 1.0883552 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 6.632393e-04 3.384698e-03 5.251854e-02 2.153175e-01 5.022002e-02 5 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5555393 0.6237799 U 0.4686274 0.6162291 13773 129 183427 183428 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.404683 3.191561 1.0883552 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.415991 3.070358 1.0357811 603 Predicted PP-loop superfamily ATPase R conserved hypothetical protein 0.000000e+00 0 1.278589e-04 1.653605e-03 3.771424e-02 9.279960e-02 1.238361e-02 0 40 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179426 0.6418162 U 0.4686274 0.6162291 13773 129 183428 183429 1 93 Convergent + - 0.000000 0 0.000000 -2.64698379 1.415991 3.070358 1.0357811 603 Predicted PP-loop superfamily ATPase R conserved hypothetical protein 1.391570 3.135923 1.0795049 388 Predicted amidohydrolase R nitrilase, conjectural -1.750951e-02 35 5.964006e-04 2.117860e-03 5.140600e-02 1.243827e-01 5.551213e-02 40 35 TRUE TRUE 101 FALSE 0.4469764 0.1925809 0.5480306 0.4469764 0.7746280 0.5247111 0.5228914 0.6218902 U 0.4686274 0.5231656 13773 129 183429 183430 1 165 Divergent - + 0.000000 0 0.000000 -0.34620364 1.391570 3.135923 1.0795049 388 Predicted amidohydrolase R nitrilase, conjectural 1.382381 3.325655 1.1313695 1280 Putative threonine efflux protein E conserved hypothetical protein 2.349122e-03 5 8.442681e-05 4.128504e-03 7.201555e-02 2.777003e-01 6.008332e-03 35 5 FALSE TRUE 100 FALSE 0.4469764 0.2486776 0.5480306 0.4469764 0.7448207 0.5028058 0.5835349 0.6454790 U 0.4686274 0.5409586 13773 129 183430 183431 1 -20 Convergent + - 0.000000 0 0.000000 -0.37419068 1.382381 3.325655 1.1313695 1280 Putative threonine efflux protein E conserved hypothetical protein 1.359300 3.043313 1.0440068 1801 Uncharacterized conserved protein S conserved hypothetical protein 1.432829e-02 5 5.327380e-04 6.355478e-03 1.044908e-01 4.117625e-01 2.523782e-02 5 22 TRUE TRUE 101 FALSE 0.4469764 0.2458726 0.5480306 0.4469764 0.7448207 0.6347855 0.6394046 0.6353762 U 0.4686274 0.5400710 13773 129 183431 183432 1 77 Divergent - + 0.000000 0 0.000000 0.00000000 1.359300 3.043313 1.0440068 1801 Uncharacterized conserved protein S conserved hypothetical protein 1.321102 2.915464 1.0112770 - - - hypothetical protein 0.000000e+00 0 1.459119e-03 1.199888e-02 1.826044e-01 6.491248e-01 2.824876e-02 22 0 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7361544 0.6339124 U 0.4686274 0.6162291 13773 129 183432 183433 1 309 Convergent + - 0.000000 0 0.000000 0.00000000 1.321102 2.915464 1.0112770 - - - hypothetical protein 1.426095 3.176603 1.0590192 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 0.000000e+00 0 1.102353e-02 3.296134e-03 1.779211e-02 1.447837e-01 5.360532e-01 0 8 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5290777 0.4857270 U 0.4686274 0.6162291 13773 129 183433 183434 1 -3 Same - - 2.079442 0 2.079442 2.07944154 1.426095 3.176603 1.0590192 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.389548 3.175174 1.0926329 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.389961e-03 6 1.335620e-03 1.564551e-03 4.711850e-02 8.189908e-02 1.182135e-01 E 8 6 FALSE TRUE 100 TRUE 2.9335626 1.6614134 0.5480306 2.9479804 0.7537284 0.4808530 0.5177251 0.6012841 Y 1.4497162 0.8895842 13773 129 183434 183435 1 -28 Same - - 0.000000 0 0.000000 0.00000000 1.389548 3.175174 1.0926329 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.371071 3.057321 1.0761615 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 1.150801e-03 1 3.414139e-04 4.967446e-03 8.548939e-02 3.303134e-01 2.171269e-02 E 6 1 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4759583 0.6039397 0.6368386 Y 1.4497162 0.7118045 13773 129 183435 183436 1 60 Divergent - + 2.197225 0 2.197225 2.19722458 1.371071 3.057321 1.0761615 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 1.456333 3.507683 1.1829865 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 3.777386e-02 1 7.269628e-03 -3.968193e-04 -2.239006e-04 -9.373080e-02 6.346085e-01 E 1 5 FALSE TRUE 98 FALSE 2.9321590 1.6745314 0.5480306 2.9469979 0.6329203 0.7874252 0.4943248 0.4721311 Y 1.4497162 0.8912321 13773 129 183436 183437 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.456333 3.507683 1.1829865 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 1.501158 3.463431 1.1958408 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 1.917743e-03 2 2.009289e-03 2.458600e-04 2.983972e-02 7.379511e-02 1.374059e-01 E 5 2 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4923490 0.5179318 0.5963968 Y 1.4497162 0.7118045 13773 129 183437 183438 1 111 Same + + 0.000000 0 0.000000 -0.05918887 1.501158 3.463431 1.1958408 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 1.350416 2.859633 0.9730803 450 Peroxiredoxin O peroxiredoxin, probable 3.702577e-04 2 2.272323e-02 -5.025157e-03 -1.841358e-02 -3.989671e-01 1.664357e+00 0 2 31 TRUE TRUE 100 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.6838149 0.4473591 0.4195269 0.4130106 N 0.5492530 0.5676209 13773 129 183438 183439 1 -78 Convergent + - 0.000000 0 0.000000 0.00000000 1.350416 2.859633 0.9730803 450 Peroxiredoxin O peroxiredoxin, probable 1.413653 3.046322 1.0685605 - - - hypothetical protein 0.000000e+00 0 3.998887e-03 3.810868e-03 4.301885e-02 2.125840e-01 2.519223e-01 31 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5543241 0.5619549 U 0.4686274 0.6162291 13773 129 183439 183440 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.413653 3.046322 1.0685605 - - - hypothetical protein 1.479886 3.210999 1.1261210 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase family 0.000000e+00 0 4.386811e-03 -1.075326e-03 6.609330e-03 -9.966846e-02 4.067366e-01 0 40 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4913774 0.5111403 U 0.4686274 0.6162291 13773 129 183440 183441 1 27 Divergent - + 0.000000 0 0.000000 0.00000000 1.479886 3.210999 1.1261210 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase family 1.460910 3.366644 1.1181029 2410 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.600687e-04 2.711814e-04 2.207676e-02 6.812074e-02 3.115780e-02 40 0 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181773 0.6322033 U 0.4686274 0.6162291 13773 129 183441 183442 1 668 Convergent + - 0.000000 0 0.000000 0.00000000 1.460910 3.366644 1.1181029 2410 Uncharacterized conserved protein S conserved hypothetical protein 1.448045 3.094767 1.0820209 665 Glycine/D-amino acid oxidases (deaminating) E conserved within P. aerophilum 0.000000e+00 0 1.655157e-04 -3.186269e-05 2.016357e-02 1.192831e-02 1.526732e-02 0 2 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186394 0.6402042 U 0.4686274 0.6162291 13773 129 183442 183443 1 37 Divergent - + 0.000000 0 0.000000 0.00000000 1.448045 3.094767 1.0820209 665 Glycine/D-amino acid oxidases (deaminating) E conserved within P. aerophilum 1.349439 3.010427 1.0522078 834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain ET bacterial extracellular solute-binding proteins, family 3 8.653935e-03 2 9.723129e-03 3.413212e-04 5.109714e-02 -4.971761e-02 7.126832e-01 2 20 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5848956 0.5067713 0.4634542 U 0.4686274 0.6162291 13773 129 183443 183444 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.349439 3.010427 1.0522078 834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain ET bacterial extracellular solute-binding proteins, family 3 1.256819 2.703019 1.0485542 199 Ribosomal protein S14 J ribosomal protein S14 3.643202e-02 8 8.578552e-03 1.983757e-02 3.224306e-01 7.691254e-01 4.198882e-02 20 8 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7652913 0.7798111 0.7726447 0.6272578 U 0.4686274 0.6162291 13773 129 183444 183445 1 35 Same + + 20.542782 0 31.402255 31.40225541 1.256819 2.703019 1.0485542 199 Ribosomal protein S14 J ribosomal protein S14 1.405787 2.995680 1.0002291 96 Ribosomal protein S8 J ribosomal protein S8 3.428670e-02 8 2.219151e-02 8.873765e-03 3.363061e-02 3.493962e-01 3.979741e-01 J 8 55 TRUE TRUE 101 TRUE 2.3591789 1.9828398 0.5480306 2.3935227 0.7652913 0.7662033 0.6125648 0.5130622 Y 1.4497162 0.9287237 13773 129 183445 183446 1 33 Same + + 0.000000 0 0.000000 0.00000000 1.405787 2.995680 1.0002291 96 Ribosomal protein S8 J ribosomal protein S8 1.335587 2.905044 1.0004998 1717 Ribosomal protein L32E J ribosomal protein L32 0.000000e+00 0 4.927981e-03 5.281440e-03 1.112650e-01 3.025923e-01 2.488501e-01 J 55 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5926156 0.5634081 Y 1.4497162 0.7118045 13773 129 183446 183447 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.335587 2.905044 1.0004998 1717 Ribosomal protein L32E J ribosomal protein L32 1.410885 2.949979 1.0294990 2147 Ribosomal protein L19E J ribosomal protein L19 0.000000e+00 0 5.669718e-03 4.691069e-03 4.569686e-02 2.613297e-01 2.994265e-01 J 0 11 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5746843 0.5419791 Y 1.4497162 0.7118045 13773 129 183447 183448 1 2 Same + + 25.178204 0 32.982047 32.98204723 1.410885 2.949979 1.0294990 2147 Ribosomal protein L19E J ribosomal protein L19 1.421178 2.985636 1.0521063 256 Ribosomal protein L18 J ribosomal protein L18 3.056801e-01 11 1.059481e-04 1.223953e-03 3.319983e-02 6.415739e-02 9.350875e-03 J 11 11 TRUE TRUE 104 TRUE 2.2337636 1.9903398 0.5480306 2.3762174 0.7764261 1.2244861 0.5183205 0.6432396 Y 1.4497162 0.9303678 13773 129 183448 183449 1 349 Same + + 0.000000 0 0.000000 0.00000000 1.421178 2.985636 1.0521063 256 Ribosomal protein L18 J ribosomal protein L18 1.469440 3.876357 1.1725641 - - - hypothetical protein 0.000000e+00 0 2.329263e-03 -5.453033e-04 1.287056e-02 -5.595682e-02 2.271404e-01 11 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5050583 0.5719932 U 0.4686274 0.6162291 13773 129 183449 183450 1 277 Convergent + - 0.000000 0 0.000000 0.00000000 1.469440 3.876357 1.1725641 - - - hypothetical protein 1.474824 3.172342 0.9978604 - - - paREP2b 0.000000e+00 0 2.897991e-05 4.228645e-04 2.624899e-02 8.362778e-02 2.120380e-03 0 0 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176871 0.6501030 U 0.4686274 0.6162291 13773 129 183450 183451 1 125 Divergent - + 0.000000 0 0.000000 0.00000000 1.474824 3.172342 0.9978604 - - - paREP2b 1.452525 3.134514 1.0815667 - - - paREP2a 0.000000e+00 0 4.972486e-04 2.651560e-05 1.965678e-02 3.460460e-02 4.105055e-02 0 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175491 0.6277229 U 0.4686274 0.6162291 13773 129 183451 183452 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.452525 3.134514 1.0815667 - - - paREP2a 1.304342 2.670667 0.9358192 - - - paREP2a 0.000000e+00 0 2.195811e-02 -1.664116e-04 7.370306e-02 -1.033049e-01 1.092611e+00 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4900013 0.4334958 U 0.4686274 0.6162291 13773 129 183452 183453 1 60 Same + + 0.000000 0 0.000000 0.00000000 1.304342 2.670667 0.9358192 - - - paREP2a 1.385977 2.956623 1.0323009 417 DNA polymerase elongation subunit (family B) L DNA-directed DNA polymerase (B3) 0.000000e+00 0 6.664224e-03 9.619536e-03 8.916497e-02 5.064810e-01 1.544013e-01 0 14 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6749852 0.5918248 U 0.4686274 0.6162291 13773 129 183453 183454 1 52 Convergent + - 0.000000 0 0.000000 0.00000000 1.385977 2.956623 1.0323009 417 DNA polymerase elongation subunit (family B) L DNA-directed DNA polymerase (B3) 1.616774 3.441170 1.1624721 - - - hypothetical protein 0.000000e+00 0 5.326729e-02 -1.081860e-02 -4.716614e-02 -4.827787e-01 2.053051e+00 14 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4077545 0.4075347 U 0.4686274 0.6162291 13773 129 183454 183455 1 58 Divergent - + 0.000000 0 0.000000 0.00000000 1.616774 3.441170 1.1624721 - - - hypothetical protein 1.420553 3.078443 1.0565160 - - - paREP2a 0.000000e+00 0 3.850253e-02 -5.100320e-03 -1.059389e-01 -1.901027e-01 1.219643e+00 0 0 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4676311 0.4275687 U 0.4686274 0.6162291 13773 129 183455 183456 1 167 Convergent + - 0.000000 0 0.000000 0.00000000 1.420553 3.078443 1.0565160 - - - paREP2a 1.387864 2.954143 1.0206573 358 DNA primase (bacterial type) L conserved protein (toprim domain) 0.000000e+00 0 1.068569e-03 1.959221e-03 5.147937e-02 1.106885e-01 9.329907e-02 0 9 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5200650 0.6097348 U 0.4686274 0.6162291 13773 129 183456 183457 1 226 Divergent - + 0.000000 0 0.000000 -0.85598940 1.387864 2.954143 1.0206573 358 DNA primase (bacterial type) L conserved protein (toprim domain) 1.411909 3.047102 1.0656380 24 Methionine aminopeptidase J methionine aminopeptidase 1.690142e-01 9 5.781534e-04 2.508374e-03 4.377613e-02 1.528935e-01 5.022002e-02 0 9 22 FALSE TRUE 107 FALSE 0.4469764 0.2169492 0.5480306 0.4469764 0.7702221 1.1137802 0.5314662 0.6237799 N 0.5492530 0.5397069 13773 129 183457 183458 1 41 Same + + 0.000000 0 0.000000 -3.04336657 1.411909 3.047102 1.0656380 24 Methionine aminopeptidase J methionine aminopeptidase 1.352791 2.914834 1.0256696 459 Chaperonin GroEL (HSP60 family) O thermosome (chaperonin) alpha subunit 3.313658e-02 22 3.494892e-03 3.893189e-03 8.698871e-02 2.245906e-01 2.184468e-01 0 22 51 TRUE TRUE 108 TRUE 0.4469764 0.1898074 0.5480306 0.4469764 0.7773546 0.7608449 0.5593058 0.5748800 N 0.5492530 0.5311050 13773 129 183458 183459 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.352791 2.914834 1.0256696 459 Chaperonin GroEL (HSP60 family) O thermosome (chaperonin) alpha subunit 1.423448 3.372534 1.1474444 - - - hypothetical protein 0.000000e+00 0 4.992328e-03 2.755445e-03 3.024849e-02 1.444632e-01 3.277848e-01 51 0 TRUE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5289459 0.5314834 U 0.4686274 0.6162291 13773 129 183459 183460 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.423448 3.372534 1.1474444 - - - hypothetical protein 1.473181 3.248711 1.0908342 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU conjugal transfer protein, conjectural 0.000000e+00 0 2.473440e-03 -6.088836e-04 1.284086e-02 -5.644687e-02 2.374973e-01 0 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5049852 0.5677637 U 0.4686274 0.6162291 13773 129 183460 183461 1 -28 Same - - 0.000000 0 0.000000 0.00000000 1.473181 3.248711 1.0908342 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU conjugal transfer protein, conjectural 1.570763 3.441985 1.0233026 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB, conjectural 0.000000e+00 0 9.522134e-03 2.600887e-03 8.612828e-02 2.399563e-01 2.581233e-01 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5648304 0.5591829 U 0.4686274 0.6162291 13773 129 183461 183462 1 128 Divergent - + 0.000000 0 0.000000 0.00000000 1.570763 3.441985 1.0233026 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB, conjectural 1.461541 3.201038 1.0570635 - - - hypothetical protein 0.000000e+00 0 1.192934e-02 1.211409e-03 -1.022533e-03 1.577033e-01 3.722592e-01 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5336200 0.5179953 U 0.4686274 0.6162291 13773 129 183462 183463 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.461541 3.201038 1.0570635 - - - hypothetical protein 1.419632 2.970655 0.9944742 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 0.000000e+00 0 1.756410e-03 -3.223240e-04 1.926923e-02 -4.325575e-02 1.736644e-01 0 2 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5082840 0.5866463 U 0.4686274 0.6162291 13773 129 183463 183464 1 230 Convergent + - 0.000000 0 0.000000 0.00000000 1.419632 2.970655 0.9944742 1958 Small nuclear ribonucleoprotein (snRNP) homolog K small nuclear ribonucleoprotein homolog (Sm-like) 1.455468 3.020050 1.0105462 - - - paREP2a 0.000000e+00 0 1.284263e-03 -1.294403e-04 1.670463e-02 -2.968532e-02 1.262621e-01 2 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5121378 0.5992342 U 0.4686274 0.6162291 13773 129 183464 183465 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.455468 3.020050 1.0105462 - - - paREP2a 1.430078 2.895921 0.9853456 - - - paREP2a 0.000000e+00 0 6.446910e-04 -8.686904e-05 2.083362e-02 -1.540957e-02 6.202126e-02 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5168916 0.6198120 U 0.4686274 0.6162291 13773 129 183465 183466 1 158 Divergent - + 0.000000 0 0.000000 0.00000000 1.430078 2.895921 0.9853456 - - - paREP2a 1.445845 3.126557 1.0264346 - - - paREP2b 0.000000e+00 0 2.486105e-04 1.182566e-04 2.104473e-02 -4.490788e-03 2.367772e-02 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197446 0.6360087 U 0.4686274 0.6162291 13773 129 183466 183467 1 44 Same + + 0.000000 0 0.000000 0.00000000 1.445845 3.126557 1.0264346 - - - paREP2b 1.484311 3.185995 1.1049887 - - - paREP2b 0.000000e+00 0 1.479671e-03 -1.826306e-04 2.127604e-02 1.580036e-02 1.328919e-01 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181336 0.5976378 U 0.4686274 0.6162291 13773 129 183467 183468 1 33 Convergent + - 0.000000 0 0.000000 0.00000000 1.484311 3.185995 1.1049887 - - - paREP2b 1.461445 3.254641 1.1284559 1201 Lhr-like helicases R ATP-dependent helicase, putative 0.000000e+00 0 5.228585e-04 3.309115e-04 2.211153e-02 7.807239e-02 4.421934e-02 0 5 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178204 0.6262469 U 0.4686274 0.6162291 13773 129 183468 183469 1 162 Same - - 0.000000 0 0.000000 -0.24283734 1.461445 3.254641 1.1284559 1201 Lhr-like helicases R ATP-dependent helicase, putative 1.374847 2.960799 1.0438097 1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain C fumarate hydratase class I beta subunit 7.445728e-03 5 7.499337e-03 -7.694765e-04 2.636396e-02 -1.221551e-01 6.806567e-01 5 15 FALSE TRUE 107 TRUE 0.4469764 0.2674215 0.5480306 0.4469764 0.7448207 0.5726570 0.4845064 0.4667437 U 0.4686274 0.5468830 13773 129 183469 183470 1 106 Divergent - + 21.432712 0 47.882868 47.82402712 1.374847 2.960799 1.0438097 1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain C fumarate hydratase class I beta subunit 1.537623 3.315732 1.0704778 1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain C fumarate hydratase class I alpha subunit 5.041264e-01 15 2.649601e-02 -6.600560e-03 -5.243507e-02 -4.454783e-01 1.787341e+00 C 15 15 FALSE TRUE 106 FALSE 2.3308952 2.0390660 0.5480306 2.1909433 0.7783720 1.2594416 0.4124036 0.4109643 Y 1.4497162 0.9335406 13773 129 183470 183471 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.537623 3.315732 1.0704778 1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain C fumarate hydratase class I alpha subunit 1.388803 3.127042 1.0963674 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 0.000000e+00 0 2.214715e-02 -5.397072e-03 -5.130066e-02 -3.588725e-01 1.474090e+00 0 15 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4266057 0.4175856 N 0.5492530 0.6245624 13773 129 183471 183472 1 30 Divergent - + 0.000000 0 0.000000 0.00000000 1.388803 3.127042 1.0963674 3609 Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain K conserved hypothetical protein 1.422988 2.979057 1.0054856 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R hypothetical protein 0.000000e+00 0 1.168602e-03 1.777835e-03 3.362519e-02 9.801633e-02 9.997827e-02 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183566 0.6068453 U 0.4686274 0.6162291 13773 129 183472 183473 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.422988 2.979057 1.0054856 1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family R hypothetical protein 1.393848 3.105576 1.0364820 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 0.000000e+00 0 8.491336e-04 1.634535e-03 4.620947e-02 9.018093e-02 7.591019e-02 0 5 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178139 0.6161199 U 0.4686274 0.6162291 13773 129 183473 183474 1 146 Divergent - + 0.000000 0 0.000000 0.00000000 1.393848 3.105576 1.0364820 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 1.401546 3.068322 1.0982005 - - - paREP2a 0.000000e+00 0 5.924927e-05 2.868438e-03 5.217702e-02 1.882662e-01 4.356203e-03 5 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5455462 0.6468997 U 0.4686274 0.6162291 13773 129 183474 183475 1 171 Convergent + - 0.000000 0 0.000000 0.00000000 1.401546 3.068322 1.0982005 - - - paREP2a 1.509941 3.254298 1.0638795 720 6-pyruvoyl-tetrahydropterin synthase H hypothetical protein 0.000000e+00 0 1.174949e-02 -2.918448e-03 -1.099060e-02 -2.268453e-01 9.336038e-01 0 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4578554 0.4442659 U 0.4686274 0.6162291 13773 129 183475 183476 1 104 Divergent - + 0.000000 0 0.000000 0.00000000 1.509941 3.254298 1.0638795 720 6-pyruvoyl-tetrahydropterin synthase H hypothetical protein 1.385731 2.989898 1.0324793 177 Predicted EndoIII-related endonuclease L conserved hypothetical protein 0.000000e+00 0 1.542812e-02 -3.844376e-03 -2.196777e-02 -3.077996e-01 1.231538e+00 0 0 1 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4381692 0.4273500 N 0.5492530 0.6245624 13773 129 183476 183477 1 168 Convergent + - 0.000000 0 0.000000 0.00000000 1.385731 2.989898 1.0324793 177 Predicted EndoIII-related endonuclease L conserved hypothetical protein 1.742999 3.897371 1.0961157 - - - hypothetical protein 0.000000e+00 0 1.276407e-01 -1.914748e-02 1.855965e-03 -5.364508e-01 2.337167e+00 1 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3998290 0.4048015 U 0.4686274 0.6162291 13773 129 183477 183478 1 634 Divergent - + 0.000000 0 0.000000 0.00000000 1.742999 3.897371 1.0961157 - - - hypothetical protein 1.475479 3.421772 1.1130212 - - - hypothetical protein 0.000000e+00 0 7.156683e-02 7.023763e-03 -1.116103e-01 3.191543e-01 4.335965e-01 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5992348 0.5065808 U 0.4686274 0.6162291 13773 129 183478 183479 1 256 Same + + 0.000000 0 0.000000 0.00000000 1.475479 3.421772 1.1130212 - - - hypothetical protein 1.379814 2.845305 1.0041004 - - - hypothetical protein 0.000000e+00 0 9.151858e-03 -1.724082e-03 1.211719e-02 -1.898482e-01 8.270807e-01 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4677698 0.4523017 U 0.4686274 0.6162291 13773 129 183479 183480 1 317 Convergent + - 0.000000 0 0.000000 0.00000000 1.379814 2.845305 1.0041004 - - - hypothetical protein 1.719035 3.592622 1.0798422 - - - conserved within P. aerophilum 0.000000e+00 0 1.150711e-01 -1.915755e-02 -3.435765e-02 -5.708911e-01 2.436762e+00 0 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3966034 0.4038977 U 0.4686274 0.6162291 13773 129 183480 183481 1 271 Same - - 0.000000 0 0.000000 0.00000000 1.719035 3.592622 1.0798422 - - - conserved within P. aerophilum 1.555352 3.241795 1.0717990 - - - conserved hypothetical protein part 2, authentic frameshift 0.000000e+00 0 2.679237e-02 2.782376e-02 1.915951e-01 7.454549e-01 4.519295e-02 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7657852 0.6259433 U 0.4686274 0.6162291 13773 129 183481 183482 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.555352 3.241795 1.0717990 - - - conserved hypothetical protein part 2, authentic frameshift 1.683114 3.735403 1.0706577 535 Predicted Fe-S oxidoreductases R conserved hypothetical protein part 1, authentic frameshift 0.000000e+00 0 1.632335e-02 2.408947e-02 4.113117e-01 7.337339e-01 3.890249e-02 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7630636 0.6284750 U 0.4686274 0.6162291 13773 129 183482 183483 1 6 Same - - 0.000000 0 0.000000 0.00000000 1.683114 3.735403 1.0706577 535 Predicted Fe-S oxidoreductases R conserved hypothetical protein part 1, authentic frameshift 1.654863 3.395133 1.0351028 - - - hypothetical protein 0.000000e+00 0 7.981208e-04 4.714851e-02 5.407890e-01 8.996536e-01 6.031303e-04 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8046663 0.6529329 U 0.4686274 0.6162291 13773 129 183483 183484 1 255 Divergent - + 0.000000 0 0.000000 0.00000000 1.654863 3.395133 1.0351028 - - - hypothetical protein 1.406416 3.174674 1.0543200 - - - hypothetical protein 0.000000e+00 0 6.172630e-02 -9.151544e-03 -1.862638e-01 -3.247951e-01 1.646583e+00 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4345528 0.4134553 U 0.4686274 0.6162291 13773 129 183484 183485 1 45 Same + + 0.000000 0 0.000000 0.00000000 1.406416 3.174674 1.0543200 - - - hypothetical protein 1.471567 3.222173 1.0877802 2848 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.244696e-03 -9.073750e-04 6.024667e-03 -9.743852e-02 3.941103e-01 0 1 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4927210 0.5133624 U 0.4686274 0.6162291 13773 129 183485 183486 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.471567 3.222173 1.0877802 2848 Uncharacterized conserved protein S conserved hypothetical protein 1.561607 3.459527 1.1090311 2411 Uncharacterized conserved protein S conserved hypothetical protein 7.562104e-04 1 8.107146e-03 2.223463e-03 7.654909e-02 2.198834e-01 2.519223e-01 1 4 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5569523 0.5619549 U 0.4686274 0.6162291 13773 129 183486 183487 1 -34 Same + + 0.000000 0 0.000000 -0.13353139 1.561607 3.459527 1.1090311 2411 Uncharacterized conserved protein S conserved hypothetical protein 1.522550 3.319016 1.1295770 1533 DNA repair photolyase L conserved hypothetical protein 4.118834e-02 1 1.525384e-03 7.842549e-03 9.444593e-02 4.962396e-01 2.216739e-02 4 1 TRUE TRUE 107 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.8108260 0.6717928 0.6366745 U 0.4686274 0.5517368 13773 129 183487 183488 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.522550 3.319016 1.1295770 1533 DNA repair photolyase L conserved hypothetical protein 1.471518 3.335881 1.1448183 - - - hypothetical protein 0.000000e+00 0 2.604283e-03 1.432078e-03 2.565196e-02 1.775759e-01 1.251737e-01 1 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5412027 0.5995746 U 0.4686274 0.6162291 13773 129 183488 183489 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.471518 3.335881 1.1448183 - - - hypothetical protein 1.431830 3.150398 1.0979931 433 Predicted ATPase R conserved within P. aerophilum 0.000000e+00 0 1.575170e-03 -3.937135e-04 1.607759e-02 -2.622792e-02 1.396912e-01 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5133970 0.5958874 U 0.4686274 0.6162291 13773 129 183489 183490 1 19 Same - - 0.000000 0 0.000000 0.00000000 1.431830 3.150398 1.0979931 433 Predicted ATPase R conserved within P. aerophilum 1.443341 3.216731 1.0884292 1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon KH conserved hypothetical protein 0.000000e+00 0 1.325042e-04 1.575200e-04 2.177221e-02 -1.796433e-03 1.272758e-02 0 5 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199667 0.6416331 U 0.4686274 0.6162291 13773 129 183490 183491 1 -24 Same - - 0.000000 0 0.000000 -0.23681685 1.443341 3.216731 1.0884292 1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon KH conserved hypothetical protein 1.468542 3.333280 1.1268670 235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases G fuculose-1-phosphate aldolase (fucA) 3.568164e-03 5 6.350834e-04 -1.380821e-04 1.970538e-02 4.859204e-03 5.479120e-02 5 19 FALSE TRUE 105 TRUE 0.4469764 0.2687705 0.5480306 0.4469764 0.7448207 0.5299793 0.5195126 0.6224019 U 0.4686274 0.5473089 13773 129 183491 183492 1 36 Same - - 0.000000 0 0.000000 -0.13353139 1.468542 3.333280 1.1268670 235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases G fuculose-1-phosphate aldolase (fucA) 1.338453 2.943446 1.0323767 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 6.872859e-06 4 1.692309e-02 -1.936797e-03 2.973777e-02 -2.126388e-01 1.194349e+00 0 19 4 FALSE TRUE 104 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.7323301 0.4389225 0.4610279 0.4283385 N 0.5492530 0.5604716 13773 129 183492 183493 1 33 Same - - 0.000000 0 0.000000 -0.34508363 1.338453 2.943446 1.0323767 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 1.439150 3.089705 1.0509776 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R conserved hypothetical protein 5.306036e-02 4 1.013993e-02 1.382680e-03 4.892520e-03 1.610900e-02 6.730798e-01 4 29 FALSE TRUE 103 TRUE 0.4469764 0.2490736 0.5480306 0.4469764 0.7323301 0.8617341 0.5180745 0.4678741 U 0.4686274 0.5410839 13773 129 183493 183494 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.439150 3.089705 1.0509776 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R conserved hypothetical protein 1.378112 3.028547 1.0430548 - - - hypothetical protein 0.000000e+00 0 3.725724e-03 8.971558e-04 4.448441e-02 1.147067e-02 3.348527e-01 29 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187480 0.5297247 U 0.4686274 0.6162291 13773 129 183494 183495 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.378112 3.028547 1.0430548 - - - hypothetical protein 1.518654 3.205375 1.0442966 1591 Holliday junction resolvase - archaeal type L Holliday Junction Resolvase 0.000000e+00 0 1.975222e-02 -4.928994e-03 -3.904211e-02 -3.670613e-01 1.468505e+00 0 3 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4243464 0.4178096 U 0.4686274 0.6162291 13773 129 183495 183496 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.518654 3.205375 1.0442966 1591 Holliday junction resolvase - archaeal type L Holliday Junction Resolvase 1.417715 3.166719 1.0499350 - - - hypothetical protein 0.000000e+00 0 1.018879e-02 -2.265243e-03 -1.435672e-02 -1.455994e-01 7.243930e-01 3 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4780369 0.4624347 U 0.4686274 0.6162291 13773 129 183496 183497 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.417715 3.166719 1.0499350 - - - hypothetical protein 1.383164 3.010882 1.0469656 2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB K transcription initiation factor TFIID (TATA-binding) 0.000000e+00 0 1.193747e-03 2.297833e-03 5.654611e-02 1.328595e-01 1.043940e-01 0 11 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5252833 0.6046210 U 0.4686274 0.6162291 13773 129 183497 183498 1 95 Same - - 2.890372 0 8.496990 7.63256942 1.383164 3.010882 1.0469656 2101 TATA-box binding protein (TBP), component of TFIID and TFIIIB K transcription initiation factor TFIID (TATA-binding) 1.458463 3.056240 1.0817038 442 Prolyl-tRNA synthetase J prolyl-tRNA synthetase 1.886248e-01 11 5.669969e-03 -4.823968e-04 3.402429e-03 -8.943291e-02 5.182232e-01 0 11 25 FALSE TRUE 98 TRUE 2.8691690 1.8171790 0.5480306 2.7894437 0.7764261 1.1239927 0.4952488 0.4901366 N 0.5492530 0.8696358 13773 129 183498 183499 1 483 Same - - 0.000000 0 0.000000 -0.70391989 1.458463 3.056240 1.0817038 442 Prolyl-tRNA synthetase J prolyl-tRNA synthetase 1.507491 3.318972 1.0940527 2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferases J beta-aspartate methyltransferase (pimT), conjectural 1.137211e-02 17 2.403733e-03 3.966289e-04 3.324008e-02 8.833031e-02 1.550051e-01 J 25 17 FALSE TRUE 97 TRUE 0.4469764 0.2240998 0.5480306 0.4469764 0.7782882 0.6070414 0.5177380 0.5915122 Y 1.4497162 0.6372571 13773 129 183499 183500 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.507491 3.318972 1.0940527 2519 tRNA(1-methyladenosine) methyltransferase and related methyltransferases J beta-aspartate methyltransferase (pimT), conjectural 1.522746 3.603032 1.1515391 - - - hypothetical protein 0.000000e+00 0 2.327269e-04 4.002802e-03 7.247720e-02 3.520473e-01 6.870031e-03 17 0 FALSE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6133912 0.6445676 U 0.4686274 0.6162291 13773 129 183500 183501 1 390 Divergent - + 0.000000 0 0.000000 0.00000000 1.522746 3.603032 1.1515391 - - - hypothetical protein 1.405493 2.958180 0.9913773 4830 Ribosomal protein S26 J ribosomal protein S26 0.000000e+00 0 1.374844e-02 -3.275143e-03 -2.513536e-02 -2.275368e-01 9.877583e-01 0 1 FALSE TRUE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4577017 0.4404584 U 0.4686274 0.6162291 13773 129 183501 183502 1 598 Same + + 0.000000 0 0.000000 0.00000000 1.405493 2.958180 0.9913773 4830 Ribosomal protein S26 J ribosomal protein S26 1.475379 3.269243 1.0758280 - - - paREP2b, degenerate 0.000000e+00 0 4.884121e-03 -1.100975e-03 3.975553e-03 -1.152780e-01 4.623583e-01 1 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4866333 0.5012753 U 0.4686274 0.6162291 13773 129 183502 183503 1 -70 Same + + 0.000000 0 0.000000 0.00000000 1.475379 3.269243 1.0758280 - - - paREP2b, degenerate 1.430815 3.170735 1.0149498 - - - paREP2b, degenerate 0.000000e+00 0 1.985986e-03 -4.935927e-04 1.458076e-02 -3.413812e-02 1.833917e-01 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5108186 0.5843367 U 0.4686274 0.6162291 13773 129 183503 183504 1 547 Same + + 0.000000 0 0.000000 0.00000000 1.430815 3.170735 1.0149498 - - - paREP2b, degenerate 1.539685 3.484837 1.1195828 1901 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 1.185284e-02 -1.816898e-03 1.821560e-02 -7.551026e-02 6.705636e-01 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4995700 0.4684793 U 0.4686274 0.6162291 13773 129 183504 183505 1 37 Same + + 0.000000 0 0.000000 0.00000000 1.539685 3.484837 1.1195828 1901 Uncharacterized conserved protein S hypothetical protein 1.484164 3.488904 1.1327288 558 Phosphatidylglycerophosphate synthase I CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) 0.000000e+00 0 3.082604e-03 2.893475e-03 3.749939e-02 2.861729e-01 9.708748e-02 0 5 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5869258 0.6079718 U 0.4686274 0.6162291 13773 129 183505 183506 1 49 Same + + 2.856470 0 2.856470 2.85647021 1.484164 3.488904 1.1327288 558 Phosphatidylglycerophosphate synthase I CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (pgsA) 1.456859 3.123121 1.0381684 5399 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.980709e-02 2 7.455806e-04 1.791319e-04 2.018068e-02 5.883642e-02 6.492132e-02 5 2 TRUE TRUE 100 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6838149 0.6786740 0.5186225 0.6191240 U 0.4686274 0.8518227 13773 129 183506 183507 1 503 Same + + 0.000000 0 0.000000 0.00000000 1.456859 3.123121 1.0381684 5399 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.530790 3.331979 1.0675976 - - - conserved hypothetical protein 3.728161e-04 1 5.465853e-03 4.339947e-04 4.174517e-02 1.001232e-01 2.877833e-01 2 1 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.5186879 0.5479032 U 0.4686274 0.6162291 13773 129 183507 183508 1 375 Convergent + - 0.000000 0 0.000000 0.00000000 1.530790 3.331979 1.0675976 - - - conserved hypothetical protein 1.430142 3.067958 1.0800197 417 DNA polymerase elongation subunit (family B) L DNA-directed DNA polymerase (B1) 5.631536e-04 1 1.013007e-02 -1.687256e-03 -1.385233e-02 -7.758234e-02 6.346085e-01 1 3 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.4986833 0.4721311 U 0.4686274 0.6162291 13773 129 183508 183509 1 90 Divergent - + 0.000000 0 0.000000 0.00000000 1.430142 3.067958 1.0800197 417 DNA polymerase elongation subunit (family B) L DNA-directed DNA polymerase (B1) 1.527662 3.242069 1.0621785 - - - hypothetical protein 0.000000e+00 0 9.510102e-03 -1.620773e-03 1.541255e-02 -7.540306e-02 6.044078e-01 3 0 FALSE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4996572 0.4764940 U 0.4686274 0.6162291 13773 129 183509 183510 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.527662 3.242069 1.0621785 - - - hypothetical protein 1.478027 3.222044 1.1138417 1257 Hydroxymethylglutaryl-CoA reductase I 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) 0.000000e+00 0 2.463586e-03 2.031385e-03 3.151851e-02 2.328324e-01 9.804636e-02 0 18 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5624966 0.6073008 U 0.4686274 0.6162291 13773 129 183510 183511 1 29 Divergent - + 2.856470 0 2.856470 2.85647021 1.478027 3.222044 1.1138417 1257 Hydroxymethylglutaryl-CoA reductase I 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) 1.506781 3.322542 1.1219784 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.939477e-02 1 8.267676e-04 1.475232e-03 4.397579e-02 1.929952e-01 3.981602e-02 I 18 1 FALSE TRUE 101 FALSE 2.8950318 1.7307027 0.5480306 2.9213001 0.6329203 0.6735730 0.5472558 0.6280980 Y 1.4497162 0.8983990 13773 129 183511 183512 1 34 Same + + 2.856470 0 2.856470 2.85647021 1.506781 3.322542 1.1219784 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.419243 3.037429 1.0387677 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 2.630109e-02 1 7.662816e-03 -1.780696e-03 -5.248697e-03 -1.254258e-01 6.056017e-01 1 11 TRUE TRUE 102 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6329203 0.7172240 0.4834309 0.4761308 U 0.4686274 0.8518227 13773 129 183512 183513 1 -3 Same + + 22.033436 0 35.090134 35.04931237 1.419243 3.037429 1.0387677 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.427752 3.061948 1.0587624 3425 3-hydroxy-3-methylglutaryl CoA synthase I 3-oxoacyl-[acyl-carrier-protein] synthase 7.121140e-02 11 7.240270e-05 7.600290e-04 2.841862e-02 3.218737e-02 7.520870e-03 11 48 TRUE TRUE 103 TRUE 2.3018608 2.0021688 0.5480306 2.3443289 0.7764261 0.9163569 0.5174256 0.6441287 U 0.4686274 0.8973748 13773 129 183513 183514 1 85 Same + + 0.000000 0 0.000000 0.00000000 1.427752 3.061948 1.0587624 3425 3-hydroxy-3-methylglutaryl CoA synthase I 3-oxoacyl-[acyl-carrier-protein] synthase 1.440411 3.165054 1.0470502 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 1.602343e-04 2.596226e-04 2.266029e-02 7.586248e-04 1.845261e-02 0 48 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199142 0.6384101 N 0.5492530 0.6245624 13773 129 183514 183515 1 28 Same + + 0.000000 0 0.000000 0.00000000 1.440411 3.165054 1.0470502 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.461451 3.276051 1.0497168 - - - hypothetical protein 0.000000e+00 0 4.426810e-04 -1.104567e-04 1.939682e-02 -1.043109e-03 3.981602e-02 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199868 0.6280980 U 0.4686274 0.6162291 13773 129 183515 183516 1 170 Same + + 0.000000 0 0.000000 0.00000000 1.461451 3.276051 1.0497168 - - - hypothetical protein 1.399734 2.968368 1.0225589 4901 Ribosomal protein S25 J conserved hypothetical protein 0.000000e+00 0 3.808995e-03 -5.195813e-04 2.118282e-02 -8.210759e-02 3.807354e-01 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4973005 0.5167658 U 0.4686274 0.6162291 13773 129 183516 183517 1 156 Same + + 0.000000 0 0.000000 0.00000000 1.399734 2.968368 1.0225589 4901 Ribosomal protein S25 J conserved hypothetical protein 1.455861 3.285130 1.1216696 - - - hypothetical protein 0.000000e+00 0 3.150277e-03 -2.308206e-04 1.131246e-02 -5.874100e-02 3.155973e-01 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5041705 0.5371275 U 0.4686274 0.6162291 13773 129 183517 183518 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.455861 3.285130 1.1216696 - - - hypothetical protein 1.524382 3.261773 1.0734373 1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins R pyruvate formate-lyase activating enzyme homolog 0.000000e+00 0 4.695187e-03 3.261278e-04 3.802935e-02 8.944410e-02 2.550134e-01 0 9 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177814 0.5607931 U 0.4686274 0.6162291 13773 129 183518 183519 1 69 Divergent - + 0.000000 0 0.000000 -0.31193905 1.524382 3.261773 1.0734373 1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins R pyruvate formate-lyase activating enzyme homolog 1.533788 3.268822 1.0696210 3642 Mn2+-dependent serine/threonine protein kinase T conserved hypothetical protein 4.919271e-02 5 8.846569e-05 6.013990e-03 9.476642e-02 4.452438e-01 2.264094e-03 9 5 FALSE TRUE 107 FALSE 0.4469764 0.2541155 0.5480306 0.4469764 0.7448207 0.8403286 0.6534252 0.6496996 U 0.4686274 0.5426787 13773 129 183519 183520 1 906 Same + + 0.000000 0 0.000000 0.00000000 1.533788 3.268822 1.0696210 3642 Mn2+-dependent serine/threonine protein kinase T conserved hypothetical protein 1.392606 3.041064 1.0665767 - - - hypothetical protein 0.000000e+00 0 1.993228e-02 -4.843728e-03 -4.436101e-02 -3.300854e-01 1.366190e+00 5 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4326072 0.4214178 U 0.4686274 0.6162291 13773 129 183520 183521 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.392606 3.041064 1.0665767 - - - hypothetical protein 1.567364 3.537567 1.1348843 618 Exopolyphosphatase-related proteins R predicted phosphoesterase 0.000000e+00 0 3.054025e-02 -6.817543e-03 -3.359647e-02 -3.799096e-01 1.621078e+00 0 5 TRUE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4231013 0.4141928 U 0.4686274 0.6162291 13773 129 183521 183522 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.567364 3.537567 1.1348843 618 Exopolyphosphatase-related proteins R predicted phosphoesterase 1.529873 3.148709 1.0606181 - - - hypothetical protein 0.000000e+00 0 1.405579e-03 9.101430e-03 1.086407e-01 5.387143e-01 1.415059e-02 5 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6919481 0.6408729 U 0.4686274 0.6162291 13773 129 183522 183523 1 5 Same - - 0.000000 0 0.000000 0.00000000 1.529873 3.148709 1.0606181 - - - hypothetical protein 1.447009 3.179800 1.0755337 1382 Prefoldin, chaperonin cofactor O conserved hypothetical protein 0.000000e+00 0 6.866453e-03 -3.440533e-04 1.122569e-03 3.792299e-02 3.854856e-01 0 4 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179853 0.5151711 U 0.4686274 0.6162291 13773 129 183523 183524 1 34 Same - - 0.000000 0 0.000000 0.00000000 1.447009 3.179800 1.0755337 1382 Prefoldin, chaperonin cofactor O conserved hypothetical protein 1.755887 3.932062 1.1468031 - - - hypothetical protein 0.000000e+00 0 9.540578e-02 -1.334889e-03 2.405361e-01 5.516463e-02 8.623467e-01 4 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187332 0.4491407 U 0.4686274 0.6162291 13773 129 183524 183525 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.755887 3.932062 1.1468031 - - - hypothetical protein 1.554759 3.503838 1.0851596 2136 Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 dom JA conserved hypothetical protein 0.000000e+00 0 4.045250e-02 3.147443e-02 1.804240e-01 7.496344e-01 4.987664e-02 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7671508 0.6238995 U 0.4686274 0.6162291 13773 129 183525 183526 1 -21 Same - - 0.000000 0 0.000000 0.00000000 1.554759 3.503838 1.0851596 2136 Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 dom JA conserved hypothetical protein 1.511385 3.202758 1.0643516 1997 Ribosomal protein L37AE/L43A J ribosomal protein L37 0.000000e+00 0 1.881272e-03 6.201208e-03 7.525035e-02 4.347061e-01 3.622551e-02 0 1 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6498431 0.6294602 U 0.4686274 0.6162291 13773 129 183526 183527 1 602 Same - - 0.000000 0 0.000000 0.00000000 1.511385 3.202758 1.0643516 1997 Ribosomal protein L37AE/L43A J ribosomal protein L37 1.378492 3.019106 1.0555087 2123 RNase PH-related exoribonuclease J 3' exoribonuclease family protein 1.976326e-03 1 1.766069e-02 -4.373517e-03 -2.604233e-02 -3.400524e-01 1.360813e+00 J 1 10 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4947521 0.4298366 0.4217615 Y 1.4497162 0.7118045 13773 129 183527 183528 1 2 Same - - 18.714655 0 29.574128 29.57412830 1.378492 3.019106 1.0555087 2123 RNase PH-related exoribonuclease J 3' exoribonuclease family protein 1.444196 3.225866 1.1169212 689 RNase PH J 3' exoribonuclease family protein 2.329131e-01 9 4.317069e-03 5.246347e-04 1.350705e-02 -1.691121e-02 3.893070e-01 J 10 9 FALSE TRUE 102 TRUE 2.4266354 1.9742945 0.5480306 2.4206051 0.7702221 1.1625725 0.5162565 0.5142888 Y 1.4497162 0.9274388 13773 129 183528 183529 1 -3 Same - - 15.495779 0 26.355252 26.35525248 1.444196 3.225866 1.1169212 689 RNase PH J 3' exoribonuclease family protein 1.484707 3.216043 1.0452348 1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) J conserved hypothetical protein 1.850254e-01 9 1.641114e-03 -2.397465e-04 2.062141e-02 1.152839e-02 1.425743e-01 J 9 9 FALSE TRUE 101 TRUE 2.5590003 1.9509384 0.5480306 2.4912711 0.7702221 1.1198968 0.5187263 0.5949759 Y 1.4497162 0.9242699 13773 129 183529 183530 1 0 Same - - 15.928643 0 28.985341 28.85180974 1.484707 3.216043 1.0452348 1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) J conserved hypothetical protein 1.368006 2.920201 1.0094143 1500 Predicted exosome subunit J conserved hypothetical protein 2.789541e-01 9 1.361918e-02 -2.777969e-03 3.096726e-03 -2.754350e-01 1.175968e+00 J 9 12 FALSE TRUE 100 TRUE 2.5250567 1.9551693 0.5480306 2.4662171 0.7702221 1.2100979 0.4459402 0.4294496 Y 1.4497162 0.9249390 13773 129 183530 183531 1 103 Same - - 0.000000 0 0.000000 -0.26871065 1.368006 2.920201 1.0094143 1500 Predicted exosome subunit J conserved hypothetical protein 1.477312 3.336431 1.1204701 1992 Uncharacterized conserved protein S conserved hypothetical protein 1.070649e-01 4 1.194794e-02 -2.161352e-03 -2.048561e-02 -2.296159e-01 1.034053e+00 12 4 FALSE TRUE 99 TRUE 0.4469764 0.2589639 0.5480306 0.4469764 0.7323301 1.0334229 0.4572390 0.4366685 U 0.4686274 0.5442113 13773 129 183531 183532 1 39 Divergent - + 0.000000 0 0.000000 0.00000000 1.477312 3.336431 1.1204701 1992 Uncharacterized conserved protein S conserved hypothetical protein 1.475476 3.411381 1.1629252 - - - hypothetical protein 0.000000e+00 0 3.371271e-06 6.242291e-04 2.780320e-02 1.096130e-01 2.126270e-04 4 0 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198829 0.6544230 U 0.4686274 0.6162291 13773 129 183532 183533 1 16 Convergent + - 0.000000 0 0.000000 0.00000000 1.475476 3.411381 1.1629252 - - - hypothetical protein 1.637399 3.271365 1.0710190 - - - hypothetical protein 0.000000e+00 0 2.621907e-02 4.479665e-03 1.595052e-01 2.975211e-01 3.537648e-01 0 0 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5911167 0.5241295 U 0.4686274 0.6162291 13773 129 183533 183534 1 15 Same - - 0.000000 0 0.000000 0.00000000 1.637399 3.271365 1.0710190 - - - hypothetical protein 1.439032 3.234411 1.0621691 1325 Predicted exosome subunit J conserved hypothetical protein 0.000000e+00 0 3.934940e-02 -2.299111e-03 -9.361911e-02 -2.256084e-02 8.896413e-01 0 7 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5145376 0.4477579 U 0.4686274 0.6162291 13773 129 183534 183535 1 49 Divergent - + 0.000000 0 0.000000 0.00000000 1.439032 3.234411 1.0621691 1325 Predicted exosome subunit J conserved hypothetical protein 1.527485 3.332945 1.0386432 - - - hypothetical protein 0.000000e+00 0 7.823808e-03 -9.405252e-04 2.405653e-02 -1.628452e-02 4.728541e-01 7 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5166081 0.4980443 U 0.4686274 0.6162291 13773 129 183535 183536 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.527485 3.332945 1.0386432 - - - hypothetical protein 1.434792 3.135912 1.0711758 638 20S proteasome, alpha and beta subunits O proteasome alpha subunit 0.000000e+00 0 8.591957e-03 -1.263194e-03 -8.035769e-03 -4.172908e-02 5.271005e-01 0 11 TRUE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5086220 0.4881566 U 0.4686274 0.6162291 13773 129 183536 183537 1 368 Divergent - + 0.000000 0 0.000000 -0.86882372 1.434792 3.135912 1.0711758 638 20S proteasome, alpha and beta subunits O proteasome alpha subunit 1.474510 3.206163 1.1167005 1389 DNA topoisomerase VI, subunit B L DNA topoisomerase VI (type II ) subunit b 2.996634e-01 9 1.577508e-03 -3.837622e-04 1.690787e-02 -1.956050e-02 1.396912e-01 0 11 9 FALSE TRUE 97 FALSE 0.4469764 0.2164619 0.5480306 0.4469764 0.7702221 1.2189334 0.5156308 0.5958874 N 0.5492530 0.5395526 13773 129 183537 183538 1 36 Same + + 13.557465 0 24.023896 23.84548843 1.474510 3.206163 1.1167005 1389 DNA topoisomerase VI, subunit B L DNA topoisomerase VI (type II ) subunit b 1.412962 3.074278 1.0542795 1697 DNA topoisomerase VI, subunit A L DNA topoisomerase VI (type II ) subunit a 2.996634e-01 9 3.788157e-03 -8.884089e-04 1.274378e-02 -8.897644e-02 3.565089e-01 L 9 11 TRUE TRUE 98 TRUE 2.5965907 1.9382871 0.5480306 2.5274876 0.7702221 1.2189334 0.4956506 0.5232211 Y 1.4497162 0.9228025 13773 129 183538 183539 1 72 Same + + 0.000000 0 0.000000 -0.69505644 1.412962 3.074278 1.0542795 1697 DNA topoisomerase VI, subunit A L DNA topoisomerase VI (type II ) subunit a 1.508590 3.348814 1.1351602 704 Phosphate uptake regulator P conserved hypothetical protein 1.412268e-01 7 9.144723e-03 -2.198141e-03 -4.063058e-04 -1.599379e-01 7.139796e-01 0 11 7 TRUE TRUE 99 TRUE 0.4469764 0.2254948 0.5480306 0.4469764 0.7596462 1.0817075 0.4742076 0.4632631 N 0.5492530 0.5424105 13773 129 183539 183540 1 228 Convergent + - 0.000000 0 0.000000 0.00000000 1.508590 3.348814 1.1351602 704 Phosphate uptake regulator P conserved hypothetical protein 1.448785 3.174827 1.1267683 - - - hypothetical protein 0.000000e+00 0 3.576650e-03 -1.491757e-04 1.070276e-02 3.901970e-02 2.389957e-01 7 0 TRUE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181319 0.5668045 U 0.4686274 0.6162291 13773 129 183540 183541 1 104 Same - - 0.000000 0 0.000000 0.00000000 1.448785 3.174827 1.1267683 - - - hypothetical protein 1.629950 3.323632 1.1159333 - - - hypothetical protein 0.000000e+00 0 3.282100e-02 -4.656967e-04 9.624202e-02 6.362141e-02 7.075095e-01 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183462 0.4639635 U 0.4686274 0.6162291 13773 129 183541 183542 1 241 Same - - 0.000000 0 0.000000 0.00000000 1.629950 3.323632 1.1159333 - - - hypothetical protein 1.530463 3.339661 1.0301056 2890 Methylase of polypeptide chain release factors J conserved hypothetical protein 0.000000e+00 0 9.897660e-03 1.411865e-02 1.207276e-01 6.208331e-01 5.265669e-02 0 2 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7268108 0.6230318 U 0.4686274 0.6162291 13773 129 183542 183543 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.530463 3.339661 1.0301056 2890 Methylase of polypeptide chain release factors J conserved hypothetical protein 1.452246 3.794556 1.2327908 4742 Predicted transcriptional regulator K conserved protein (possible helix-turn-helix) 0.000000e+00 0 6.117908e-03 6.748828e-05 5.651225e-03 7.217773e-02 3.313094e-01 0 2 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179893 0.5307106 N 0.5492530 0.6245624 13773 129 183543 183544 1 50 Divergent - + 0.000000 0 0.000000 0.00000000 1.452246 3.794556 1.2327908 4742 Predicted transcriptional regulator K conserved protein (possible helix-turn-helix) 1.581806 3.511249 1.0887380 1581 Archaeal DNA-binding protein K conserved hypothetical protein 0.000000e+00 0 1.678563e-02 1.113099e-04 6.522806e-02 8.786501e-02 5.237627e-01 K 0 9 FALSE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177183 0.4888416 Y 1.4497162 0.7118045 13773 129 183544 183545 1 146 Convergent + - 0.000000 0 0.000000 0.00000000 1.581806 3.511249 1.0887380 1581 Archaeal DNA-binding protein K conserved hypothetical protein 1.548791 3.267592 1.0389904 - - - paREP2a 0.000000e+00 0 1.089969e-03 1.270198e-02 1.501529e-01 6.125082e-01 8.340750e-03 9 0 TRUE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7238804 0.6438916 U 0.4686274 0.6162291 13773 129 183545 183546 1 73 Divergent - + 0.000000 0 0.000000 0.00000000 1.548791 3.267592 1.0389904 - - - paREP2a 1.499232 3.125958 1.0376264 - - - paREP2b 0.000000e+00 0 2.456064e-03 4.659483e-03 5.693881e-02 3.716979e-01 5.515108e-02 0 0 FALSE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6206856 0.6221915 U 0.4686274 0.6162291 13773 129 183546 183547 1 -24 Same + + 0.000000 0 0.000000 0.00000000 1.499232 3.125958 1.0376264 - - - paREP2b 1.377255 3.051847 1.0936951 - - - paREP2b 0.000000e+00 0 1.487840e-02 -3.546704e-03 -1.258524e-02 -3.060132e-01 1.234947e+00 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4387303 0.4269687 U 0.4686274 0.6162291 13773 129 183547 183548 1 37 Same + + 0.000000 0 0.000000 0.00000000 1.377255 3.051847 1.0936951 - - - paREP2b 1.515402 3.357184 1.1447169 43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases H conserved hypothetical protein 0.000000e+00 0 1.908439e-02 -4.745449e-03 -3.830086e-02 -3.619912e-01 1.448116e+00 0 10 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4255825 0.4185803 U 0.4686274 0.6162291 13773 129 183548 183549 1 29 Same + + 4.591747 0 6.788972 6.36951087 1.515402 3.357184 1.1447169 43 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases H conserved hypothetical protein 1.531467 3.374079 1.1343954 1679 Uncharacterized conserved protein S conserved hypothetical protein 2.329131e-01 9 2.580930e-04 5.125432e-03 8.654395e-02 4.095255e-01 8.481519e-03 10 9 TRUE TRUE 99 TRUE 2.8493358 1.8051951 0.5480306 2.8284621 0.7702221 1.1625725 0.6378622 0.6437931 U 0.4686274 0.8640739 13773 129 183549 183550 1 -7 Same + + 4.969813 0 4.969813 4.92899131 1.531467 3.374079 1.1343954 1679 Uncharacterized conserved protein S conserved hypothetical protein 1.483113 3.391754 1.1223304 1786 Uncharacterized conserved protein S conserved hypothetical protein 9.224434e-02 3 2.338096e-03 2.539956e-03 3.670781e-02 2.686191e-01 8.821310e-02 9 3 TRUE TRUE 100 TRUE 2.8267047 1.7617730 0.5480306 2.8904122 0.7136133 0.9819426 0.5780890 0.6118328 U 0.4686274 0.8577867 13773 129 183550 183551 1 231 Convergent + - 0.000000 0 0.000000 -0.19068981 1.483113 3.391754 1.1223304 1786 Uncharacterized conserved protein S conserved hypothetical protein 1.531943 3.379310 1.1098096 4047 Uncharacterized protein conserved in archaea S conserved hypothetical protein 7.283192e-02 3 2.384357e-03 2.555056e-03 6.453405e-02 2.689189e-01 8.866957e-02 3 3 TRUE TRUE 101 FALSE 0.4469764 0.2733593 0.5480306 0.4469764 0.7136133 0.9306064 0.5783208 0.6116373 U 0.4686274 0.5487570 13773 129 183551 183552 1 -34 Same - - 0.000000 0 0.000000 0.00000000 1.531943 3.379310 1.1098096 4047 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.522117 3.331698 1.0908898 2219 Eukaryotic-type DNA primase, large subunit L conserved protein (possible primase) 0.000000e+00 0 9.654513e-05 5.696839e-03 8.357205e-02 4.353423e-01 3.138751e-03 3 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6501666 0.6484515 U 0.4686274 0.6162291 13773 129 183552 183553 1 131 Same - - 0.000000 0 0.000000 0.00000000 1.522117 3.331698 1.0908898 2219 Eukaryotic-type DNA primase, large subunit L conserved protein (possible primase) 1.524334 3.465516 1.1165919 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R hypothetical protein 0.000000e+00 0 4.913905e-06 5.158698e-03 8.186338e-02 4.067077e-01 1.154429e-04 0 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6369416 0.6549470 U 0.4686274 0.6162291 13773 129 183553 183554 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.524334 3.465516 1.1165919 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R hypothetical protein 1.570402 3.508786 1.1009637 714 MoxR-like ATPases R conserved hypothetical protein 0.000000e+00 0 2.122254e-03 8.680629e-03 1.446902e-01 5.177626e-01 2.622262e-02 0 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6825953 0.6348800 U 0.4686274 0.6162291 13773 129 183554 183555 1 86 Divergent - + 0.000000 0 0.000000 0.00000000 1.570402 3.508786 1.1009637 714 MoxR-like ATPases R conserved hypothetical protein 1.541078 3.355534 1.1088260 1341 Predicted GTPase or GTP-binding protein R conserved hypothetical protein 0.000000e+00 0 8.599108e-04 1.067328e-02 1.299914e-01 5.789303e-01 7.388346e-03 0 1 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7119669 0.6442479 U 0.4686274 0.6162291 13773 129 183555 183556 1 91 Convergent + - 0.000000 0 0.000000 0.00000000 1.541078 3.355534 1.1088260 1341 Predicted GTPase or GTP-binding protein R conserved hypothetical protein 1.501669 3.290419 1.1069571 1407 Predicted ICC-like phosphoesterases R conserved hypothetical protein 1.557260e-03 1 1.553009e-03 4.509028e-03 5.945154e-02 3.708686e-01 4.136213e-02 1 8 TRUE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.6204005 0.6275054 U 0.4686274 0.6162291 13773 129 183556 183557 1 -48 Same - - 0.000000 0 0.000000 0.00000000 1.501669 3.290419 1.1069571 1407 Predicted ICC-like phosphoesterases R conserved hypothetical protein 1.514350 3.281024 1.0839918 - - - hypothetical protein 0.000000e+00 0 1.608122e-04 3.165286e-03 6.139369e-02 3.027902e-01 5.094213e-03 8 0 FALSE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5928664 0.6463003 U 0.4686274 0.6162291 13773 129 183557 183558 1 322 Divergent - + 0.000000 0 0.000000 0.00000000 1.514350 3.281024 1.0839918 - - - hypothetical protein 1.497112 3.218905 1.0747143 456 Acetyltransferases R N-acetyltransferase 0.000000e+00 0 2.971616e-04 2.878376e-03 4.963492e-02 2.852176e-01 1.026264e-02 0 18 FALSE TRUE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5864381 0.6426621 U 0.4686274 0.6162291 13773 129 183558 183559 1 86 Same + + 0.000000 0 0.000000 0.00000000 1.497112 3.218905 1.0747143 456 Acetyltransferases R N-acetyltransferase 1.470772 3.192989 1.1082247 - - - hypothetical protein 0.000000e+00 0 6.938162e-04 8.859871e-04 2.674238e-02 1.342200e-01 4.389716e-02 18 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5260628 0.6263686 U 0.4686274 0.6162291 13773 129 183559 183560 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.470772 3.192989 1.1082247 - - - hypothetical protein 1.509160 3.330507 1.0776493 - - - hypothetical protein 0.000000e+00 0 1.473687e-03 1.119468e-03 4.134769e-02 1.549998e-01 8.106978e-02 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5322701 0.6140495 U 0.4686274 0.6162291 13773 129 183560 183561 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.509160 3.330507 1.0776493 - - - hypothetical protein 1.545973 3.497432 1.1421371 - - - hypothetical protein 0.000000e+00 0 1.355145e-03 5.463636e-03 9.886226e-02 4.098883e-01 2.876708e-02 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6381698 0.6337043 U 0.4686274 0.6162291 13773 129 183561 183562 1 209 Same + + 0.000000 0 0.000000 0.00000000 1.545973 3.497432 1.1421371 - - - hypothetical protein 1.458699 3.203241 1.1033667 436 Aspartate/tyrosine/aromatic aminotransferase E aspartate aminotransferase (aspC), conjectural 0.000000e+00 0 7.616633e-03 6.910426e-04 6.236367e-03 1.194339e-01 3.216622e-01 0 63 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5219442 0.5343942 U 0.4686274 0.6162291 13773 129 183562 183563 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.458699 3.203241 1.1033667 436 Aspartate/tyrosine/aromatic aminotransferase E aspartate aminotransferase (aspC), conjectural 1.484566 3.179728 1.0578117 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 0.000000e+00 0 6.690807e-04 2.423773e-04 2.623067e-02 6.611521e-02 5.807249e-02 63 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182425 0.6210721 U 0.4686274 0.6162291 13773 129 183563 183564 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.484566 3.179728 1.0578117 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 1.493816 3.161875 1.0542496 - - - hypothetical protein 0.000000e+00 0 8.556781e-05 1.407311e-03 3.896822e-02 1.877920e-01 3.583442e-03 0 0 TRUE TRUE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5453926 0.6476453 U 0.4686274 0.6162291 13773 129 183564 183565 1 74 Divergent - + 0.000000 0 0.000000 0.00000000 1.493816 3.161875 1.0542496 - - - hypothetical protein 1.424337 3.040662 1.0438322 2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme R conserved hypothetical protein 0.000000e+00 0 4.827415e-03 -1.147817e-03 4.605664e-03 -8.338394e-02 4.146055e-01 0 6 FALSE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4971111 0.5098051 U 0.4686274 0.6162291 13773 129 183565 183566 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.424337 3.040662 1.0438322 2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme R conserved hypothetical protein 1.542874 3.834192 1.1274085 - - - hypothetical protein 0.000000e+00 0 1.405117e-02 -2.475144e-03 1.119133e-02 -1.298309e-01 8.145651e-01 6 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4816187 0.4536353 U 0.4686274 0.6162291 13773 129 183566 183567 1 333 Convergent + - 0.000000 0 0.000000 0.00000000 1.542874 3.834192 1.1274085 - - - hypothetical protein 1.831579 3.960037 1.1558647 - - - hypothetical protein 0.000000e+00 0 8.335066e-02 3.477997e-02 7.732073e-01 7.190632e-01 7.381042e-02 0 0 TRUE TRUE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7603548 0.6167268 U 0.4686274 0.6162291 13773 129 183567 183568 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.831579 3.960037 1.1558647 - - - hypothetical protein 1.457857 3.083695 1.0890576 1996 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) K DNA-directed RNA polymerase subunit 0.000000e+00 0 1.396687e-01 2.457436e-03 -3.174883e-01 1.534307e-01 7.062190e-01 0 3 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5315999 0.4641545 U 0.4686274 0.6162291 13773 129 183568 183569 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.457857 3.083695 1.0890576 1996 DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) K DNA-directed RNA polymerase subunit 1.443126 3.036764 1.0349715 1056 Nicotinamide mononucleotide adenylyltransferase H conserved protein (possible cytidylyltransferase) 0.000000e+00 0 2.169798e-04 -5.343251e-05 2.018038e-02 2.604533e-03 1.887197e-02 0 3 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197564 0.6382319 N 0.5492530 0.6245624 13773 129 183569 183570 1 251 Same - - 0.000000 0 0.000000 0.00000000 1.443126 3.036764 1.0349715 1056 Nicotinamide mononucleotide adenylyltransferase H conserved protein (possible cytidylyltransferase) 1.358050 2.946942 1.0246342 10 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family E agmatinase (speB) 0.000000e+00 0 7.238025e-03 7.716174e-04 5.171267e-02 -1.234886e-02 5.599128e-01 0 0 34 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177473 0.4824847 N 0.5492530 0.6245624 13773 129 183570 183571 1 -7 Same - - 0.000000 0 0.000000 -0.05918887 1.358050 2.946942 1.0246342 10 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family E agmatinase (speB) 1.466530 3.501772 1.1750842 53 Predicted Co/Zn/Cd cation transporters P cation efflux system protein, conjectural 1.061851e-02 1 1.176795e-02 -1.412947e-03 -1.732755e-02 -1.717614e-01 9.336038e-01 0 34 1 FALSE TRUE 99 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.6041916 0.4726362 0.4442659 N 0.5492530 0.5676209 13773 129 183571 183572 1 79 Same - - 0.000000 0 0.000000 0.00000000 1.466530 3.501772 1.1750842 53 Predicted Co/Zn/Cd cation transporters P cation efflux system protein, conjectural 1.520904 3.173844 1.0511137 - - - paREP2b 0.000000e+00 0 2.956534e-03 1.052200e-03 4.472883e-02 1.477905e-01 1.556100e-01 1 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5301354 0.5912363 U 0.4686274 0.6162291 13773 129 183572 183573 1 32 Divergent - + 0.000000 0 0.000000 0.00000000 1.520904 3.173844 1.0511137 - - - paREP2b 1.573679 3.179268 1.0382725 - - - paREP2a 0.000000e+00 0 2.785232e-03 8.500273e-03 1.458306e-01 5.119539e-01 3.392608e-02 0 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6782186 0.6305306 U 0.4686274 0.6162291 13773 129 183573 183574 1 13 Same + + 0.000000 0 0.000000 0.00000000 1.573679 3.179268 1.0382725 - - - paREP2a 1.454347 3.090628 1.0749583 423 Glycyl-tRNA synthetase (class II) J glycyl-tRNA synthetase 0.000000e+00 0 1.424010e-02 3.613040e-04 -1.299143e-02 1.011421e-01 4.749674e-01 0 14 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5189250 0.4975908 U 0.4686274 0.6162291 13773 129 183574 183575 1 57 Same + + 0.000000 0 0.000000 0.00000000 1.454347 3.090628 1.0749583 423 Glycyl-tRNA synthetase (class II) J glycyl-tRNA synthetase 1.444292 3.034543 0.9962578 - - - conserved protein 0.000000e+00 0 1.011206e-04 -2.098131e-05 2.059827e-02 3.625850e-03 9.056378e-03 14 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196581 0.6434772 U 0.4686274 0.6162291 13773 129 183575 183576 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.444292 3.034543 0.9962578 - - - conserved protein 1.489159 3.218574 1.0835706 1676 tRNA splicing endonuclease J tRNA intron endonuclease 0.000000e+00 0 2.013086e-03 -2.681888e-04 2.109594e-02 1.271286e-02 1.654485e-01 0 5 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185526 0.5885871 U 0.4686274 0.6162291 13773 129 183576 183577 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.489159 3.218574 1.0835706 1676 tRNA splicing endonuclease J tRNA intron endonuclease 1.519750 3.143469 1.0637652 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 1.917743e-03 2 9.358338e-04 2.581599e-03 5.916691e-02 2.693118e-01 3.308323e-02 0 5 2 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4923490 0.5786696 0.6310514 N 0.5492530 0.6245624 13773 129 183577 183578 1 100 Same - - 0.000000 0 0.000000 0.00000000 1.519750 3.143469 1.0637652 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 1.446602 2.897523 0.9791087 - - - hypothetical protein 0.000000e+00 0 5.350673e-03 -3.274850e-04 5.100434e-03 3.034499e-02 3.234056e-01 2 0 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173882 0.5336048 U 0.4686274 0.6162291 13773 129 183578 183579 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.446602 2.897523 0.9791087 - - - hypothetical protein 1.552699 3.394277 1.0672359 778 Nitroreductase C reductase, putative 0.000000e+00 0 1.125664e-02 -4.853361e-04 4.106774e-02 3.690403e-02 4.931208e-01 0 8 FALSE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178540 0.4934901 U 0.4686274 0.6162291 13773 129 183579 183580 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.552699 3.394277 1.0672359 778 Nitroreductase C reductase, putative 1.428682 3.064406 0.9928041 - - - hypothetical protein 0.000000e+00 0 1.538038e-02 -2.300784e-03 -3.091688e-02 -1.003328e-01 7.830145e-01 8 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4910342 0.4572662 U 0.4686274 0.6162291 13773 129 183580 183581 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.428682 3.064406 0.9928041 - - - hypothetical protein 1.440157 3.141433 1.0591549 5277 Actin and related proteins Z hypothetical protein 0.000000e+00 0 1.316807e-04 2.551793e-04 2.273205e-02 1.332305e-03 1.526732e-02 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198606 0.6402042 U 0.4686274 0.6162291 13773 129 183581 183582 1 14 Same + + 0.000000 0 0.000000 0.00000000 1.440157 3.141433 1.0591549 5277 Actin and related proteins Z hypothetical protein 1.472478 3.204149 1.0572845 - - - actin-like protein 0.000000e+00 0 1.044623e-03 -2.369058e-04 1.877610e-02 -2.871348e-03 8.866957e-02 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198828 0.6116373 U 0.4686274 0.6162291 13773 129 183582 183583 1 185 Same + + 0.000000 0 0.000000 0.00000000 1.472478 3.204149 1.0572845 - - - actin-like protein 1.461616 3.187874 1.1168131 419 ATPase involved in DNA repair L conserved hypothetical protein 0.000000e+00 0 1.179837e-04 2.155435e-04 2.239429e-02 5.698521e-02 8.062744e-03 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186761 0.6440495 U 0.4686274 0.6162291 13773 129 183583 183584 1 71 Convergent + - 0.000000 0 0.000000 0.00000000 1.461616 3.187874 1.1168131 419 ATPase involved in DNA repair L conserved hypothetical protein 1.558823 3.472804 1.1418756 1378 Predicted transcriptional regulators K conserved hypothetical protein 0.000000e+00 0 9.449373e-03 1.098233e-03 6.262247e-02 1.525684e-01 3.277848e-01 0 0 2 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5313326 0.5314834 N 0.5492530 0.6245624 13773 129 183584 183585 1 81 Divergent - + 0.000000 0 0.000000 -0.13150953 1.558823 3.472804 1.1418756 1378 Predicted transcriptional regulators K conserved hypothetical protein 1.372980 2.893449 1.0343302 1964 Predicted Fe-S oxidoreductases R molybdenum cofactor biosynthesis protein (moaA) 5.662889e-02 2 3.453784e-02 -8.423955e-03 -9.145246e-02 -4.920035e-01 1.985439e+00 2 10 FALSE TRUE 103 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.6838149 0.8734599 0.4059617 0.4081529 U 0.4686274 0.5537552 13773 129 183585 183586 1 17 Convergent + - 0.000000 0 0.000000 0.00000000 1.372980 2.893449 1.0343302 1964 Predicted Fe-S oxidoreductases R molybdenum cofactor biosynthesis protein (moaA) 1.440407 3.406955 1.1725425 - - - hypothetical protein 0.000000e+00 0 4.546452e-03 8.614138e-04 1.550164e-02 3.920347e-03 3.999131e-01 10 0 TRUE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196429 0.5126202 U 0.4686274 0.6162291 13773 129 183586 183587 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.440407 3.406955 1.1725425 - - - hypothetical protein 1.543396 3.521652 1.1519021 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter ATP-binding protein, putative 0.000000e+00 0 1.060672e-02 -1.010712e-03 3.010964e-02 -4.452798e-03 5.349300e-01 0 23 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197613 0.4860301 U 0.4686274 0.6162291 13773 129 183587 183588 1 -9 Same - - 0.000000 0 0.000000 0.00000000 1.543396 3.521652 1.1519021 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter ATP-binding protein, putative 1.455687 3.403186 1.1554707 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 0.000000e+00 0 7.692869e-03 3.950918e-04 3.908088e-03 9.851815e-02 3.474030e-01 V 23 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184799 0.5254647 Y 1.4497162 0.7118045 13773 129 183588 183589 1 58 Divergent - + 0.000000 0 0.000000 0.00000000 1.455687 3.403186 1.1554707 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 1.450820 3.367132 1.1652594 2409 Predicted drug exporters of the RND superfamily R membrane protein, putative 0.000000e+00 0 2.369147e-05 -2.460935e-06 2.066292e-02 1.240599e-02 1.981377e-03 0 0 FALSE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185960 0.6503033 U 0.4686274 0.6162291 13773 129 183589 183590 1 17 Same + + 0.000000 0 0.000000 0.00000000 1.450820 3.367132 1.1652594 2409 Predicted drug exporters of the RND superfamily R membrane protein, putative 1.442063 3.324462 1.1736143 - - - hypothetical protein 0.000000e+00 0 7.667249e-05 5.346345e-06 2.102040e-02 7.009033e-04 6.997843e-03 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199219 0.6444474 U 0.4686274 0.6162291 13773 129 183590 183591 1 27 Same + + 0.000000 0 0.000000 0.00000000 1.442063 3.324462 1.1736143 - - - hypothetical protein 1.367476 3.066169 1.0379086 1011 Predicted hydrolase (HAD superfamily) R hypothetical protein 0.000000e+00 0 5.563272e-03 7.828882e-04 4.755366e-02 -5.218490e-03 4.728541e-01 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196311 0.4980443 U 0.4686274 0.6162291 13773 129 183591 183592 1 113 Same + + 0.000000 0 0.000000 0.00000000 1.367476 3.066169 1.0379086 1011 Predicted hydrolase (HAD superfamily) R hypothetical protein 1.360815 2.688609 1.0134886 - - - hypothetical protein 0.000000e+00 0 4.436820e-05 7.600976e-03 1.125621e-01 4.884507e-01 1.472486e-03 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6693363 0.6510547 U 0.4686274 0.6162291 13773 129 183592 183593 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.360815 2.688609 1.0134886 - - - hypothetical protein 1.362462 2.989842 1.0318120 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved hypothetical protein 0.000000e+00 0 2.711127e-06 8.055168e-03 1.141704e-01 5.099514e-01 7.126832e-05 0 17 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6771361 0.6552829 U 0.4686274 0.6162291 13773 129 183593 183594 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.362462 2.989842 1.0318120 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved hypothetical protein 1.439665 3.134106 1.0695088 - - - hypothetical protein 0.000000e+00 0 5.960375e-03 1.042950e-03 1.319712e-02 9.261937e-03 4.856047e-01 17 0 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5189208 0.4950121 U 0.4686274 0.6162291 13773 129 183594 183595 1 98 Divergent - + 0.000000 0 0.000000 0.00000000 1.439665 3.134106 1.0695088 - - - hypothetical protein 1.424424 3.013785 1.0760761 525 Valyl-tRNA synthetase J valyl-tRNA synthetase 0.000000e+00 0 2.322808e-04 3.162750e-04 2.593336e-02 2.312981e-03 2.697359e-02 0 69 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197941 0.6345527 U 0.4686274 0.6162291 13773 129 183595 183596 1 -3 Convergent + - 0.000000 0 0.000000 -1.88443240 1.424424 3.013785 1.0760761 525 Valyl-tRNA synthetase J valyl-tRNA synthetase 1.396073 3.036413 1.0866118 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R ATP-dependent helicase 1.591753e-02 15 8.037975e-04 1.491883e-03 4.410582e-02 8.122645e-02 7.889933e-02 69 15 TRUE TRUE 106 FALSE 0.4469764 0.1974839 0.5480306 0.4469764 0.7783720 0.6430980 0.5177366 0.6150837 U 0.4686274 0.5247237 13773 129 183596 183597 1 84 Divergent - + 0.000000 0 0.000000 0.00000000 1.396073 3.036413 1.0866118 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R ATP-dependent helicase 1.341847 2.911209 0.9959901 - - - conserved within P. aerophilum 0.000000e+00 0 2.940426e-03 6.060019e-03 1.142962e-01 3.772986e-01 1.334520e-01 15 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6241345 0.5974546 U 0.4686274 0.6162291 13773 129 183597 183598 1 88 Same + + 0.000000 0 0.000000 0.00000000 1.341847 2.911209 0.9959901 - - - conserved within P. aerophilum 1.506234 3.441775 1.1481316 1132 ABC-type multidrug transport system, ATPase and permease components V ABC transporter ATP-binding component, degenerate 0.000000e+00 0 2.702310e-02 -6.007650e-03 -7.234220e-02 -4.480816e-01 1.870366e+00 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4121842 0.4100105 U 0.4686274 0.6162291 13773 129 183598 183599 1 1030 Convergent + - 0.000000 0 0.000000 0.00000000 1.506234 3.441775 1.1481316 1132 ABC-type multidrug transport system, ATPase and permease components V ABC transporter ATP-binding component, degenerate 1.400924 3.412381 1.1917795 477 Permeases of the major facilitator superfamily GEPR resistance protein, conjectural 0.000000e+00 0 1.109039e-02 -2.767819e-03 -1.279376e-02 -2.225792e-01 9.085616e-01 0 3 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4590764 0.4456325 U 0.4686274 0.6162291 13773 129 183599 183600 1 -3 Same - - 0.000000 0 0.000000 -0.11903382 1.400924 3.412381 1.1917795 477 Permeases of the major facilitator superfamily GEPR resistance protein, conjectural 1.386908 2.880587 1.0006783 1839 Uncharacterized conserved protein S conserved hypothetical protein 3.747475e-03 3 1.964472e-04 3.254524e-03 6.288215e-02 2.175563e-01 1.507826e-02 3 12 FALSE TRUE 106 TRUE 0.4469764 0.2932604 0.5480306 0.4469764 0.7136133 0.5321665 0.5562425 0.6403514 U 0.4686274 0.5550278 13773 129 183600 183601 1 85 Divergent - + 0.000000 0 0.000000 -0.62878219 1.386908 2.880587 1.0006783 1839 Uncharacterized conserved protein S conserved hypothetical protein 1.365410 2.931775 1.0257456 735 Fe2+/Zn2+ uptake regulation proteins P ferric uptake regulator, putative 3.489358e-02 12 4.621285e-04 5.544597e-03 9.378105e-02 3.681722e-01 2.572786e-02 12 17 FALSE TRUE 105 FALSE 0.4469764 0.2296104 0.5480306 0.4469764 0.7776747 0.7689006 0.6192641 0.6351292 U 0.4686274 0.5349202 13773 129 183601 183602 1 107 Same + + 0.000000 0 0.000000 -0.26682824 1.365410 2.931775 1.0257456 735 Fe2+/Zn2+ uptake regulation proteins P ferric uptake regulator, putative 1.464285 3.092577 1.0915864 665 Glycine/D-amino acid oxidases (deaminating) E proline dehydrogenase -8.914191e-03 8 9.776092e-03 -1.108460e-03 -1.057521e-02 -1.487564e-01 8.228982e-01 0 17 8 TRUE TRUE 106 TRUE 0.4469764 0.2593289 0.5480306 0.4469764 0.7652913 0.5247582 0.4770289 0.4528094 N 0.5492530 0.5530890 13773 129 183602 183603 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.464285 3.092577 1.0915864 665 Glycine/D-amino acid oxidases (deaminating) E proline dehydrogenase 1.469237 3.167382 1.1064025 - - - hypothetical protein 0.000000e+00 0 2.452817e-05 2.300434e-04 2.381399e-02 5.673194e-02 2.412521e-03 8 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186841 0.6495169 U 0.4686274 0.6162291 13773 129 183603 183604 1 53 Same + + 0.000000 0 0.000000 0.00000000 1.469237 3.167382 1.1064025 - - - hypothetical protein 1.367392 2.897779 1.0294116 45 Succinyl-CoA synthetase, beta subunit C succinyl-CoA synthetase beta subunit (sucC) 0.000000e+00 0 1.037235e-02 -1.498929e-03 2.032214e-02 -1.797187e-01 8.925391e-01 0 44 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4707718 0.4471312 U 0.4686274 0.6162291 13773 129 183604 183605 1 -3 Same + + 65.606532 0 161.442917 160.82331113 1.367392 2.897779 1.0294116 45 Succinyl-CoA synthetase, beta subunit C succinyl-CoA synthetase beta subunit (sucC) 1.469391 3.179686 1.1051900 74 Succinyl-CoA synthetase, alpha subunit C succinyl-CoA synthetase alpha subunit (sucD) 6.103390e-01 44 1.040374e-02 -1.511861e-03 -1.403574e-02 -1.807636e-01 8.954417e-01 C 44 45 TRUE TRUE 109 TRUE 2.0330550 2.0786883 0.5480306 2.0362540 0.7723149 1.2651653 0.4699621 0.4468809 Y 1.4497162 0.9387625 13773 129 183605 183606 1 302 Same + + 0.000000 0 0.000000 -3.59739026 1.469391 3.179686 1.1051900 74 Succinyl-CoA synthetase, alpha subunit C succinyl-CoA synthetase alpha subunit (sucD) 1.424130 3.127407 1.0910040 1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR KE aminotransferase, class I 2.652383e-02 28 2.048530e-03 -4.906761e-04 1.606539e-02 -4.891010e-02 2.022583e-01 45 28 TRUE TRUE 110 TRUE 0.4469764 0.1864318 0.5480306 0.4469764 0.7759129 0.7196957 0.5069108 0.5792906 U 0.4686274 0.5212107 13773 129 183606 183607 1 -3 Same + + 0.000000 0 0.000000 -1.08208674 1.424130 3.127407 1.0910040 1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR KE aminotransferase, class I 1.536165 3.333554 1.1172852 1171 Threonine dehydratase E threonine dehydratase (ilvA) 5.157557e-03 22 1.255182e-02 -2.311104e-03 1.007799e-02 -1.289191e-01 7.816568e-01 28 22 TRUE TRUE 111 TRUE 0.4469764 0.2079743 0.5480306 0.4469764 0.7773546 0.5441913 0.4821044 0.4573938 U 0.4686274 0.5280559 13773 129 183607 183608 1 29 Same + + 0.000000 0 0.000000 -0.50412182 1.536165 3.333554 1.1172852 1171 Threonine dehydratase E threonine dehydratase (ilvA) 1.482018 2.993575 1.0027465 2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain R alanyl-tRNA synthetase related protein 1.948322e-03 14 2.931950e-03 2.596153e-03 3.522457e-02 2.675071e-01 1.009513e-01 22 14 TRUE TRUE 112 TRUE 0.4469764 0.2349383 0.5480306 0.4469764 0.7782928 0.4935462 0.5769393 0.6063831 U 0.4686274 0.5366086 13773 129 183608 183609 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.482018 2.993575 1.0027465 2872 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain R alanyl-tRNA synthetase related protein 1.465080 3.586566 1.2112046 475 Kef-type K+ transport systems, membrane components P hypothetical protein 0.000000e+00 0 2.868846e-04 4.191728e-04 2.373276e-02 8.476925e-02 2.572786e-02 14 0 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176818 0.6351292 U 0.4686274 0.6162291 13773 129 183609 183610 1 615 Same + + 0.000000 0 0.000000 0.00000000 1.465080 3.586566 1.2112046 475 Kef-type K+ transport systems, membrane components P hypothetical protein 1.407812 3.125693 1.0494119 - - - hypothetical protein 0.000000e+00 0 3.279629e-03 -5.965025e-04 1.811070e-02 -7.336455e-02 3.053347e-01 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5004304 0.5400080 U 0.4686274 0.6162291 13773 129 183610 183611 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.407812 3.125693 1.0494119 - - - hypothetical protein 1.401978 3.009330 1.0210472 3294 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.403748e-05 2.153539e-03 4.729529e-02 1.314977e-01 4.458099e-03 0 3 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5249066 0.6467962 U 0.4686274 0.6162291 13773 129 183611 183612 1 120 Divergent - + 2.079442 0 2.079442 2.07944154 1.401978 3.009330 1.0210472 3294 Uncharacterized conserved protein S conserved hypothetical protein 1.625129 3.445891 1.0678782 1324 Uncharacterized protein involved in tolerance to divalent cations P divalent cation tolerance protein, conjectural 1.286114e-04 3 4.979624e-02 -8.585139e-03 -9.190362e-03 -3.594067e-01 1.694193e+00 3 22 FALSE TRUE 114 FALSE 2.9335626 1.6614134 0.5480306 2.9479804 0.7136133 0.4408068 0.4264016 0.4122525 U 0.4686274 0.8396881 13773 129 183612 183613 1 -7 Same + + 0.000000 0 0.000000 -1.10596666 1.625129 3.445891 1.0678782 1324 Uncharacterized protein involved in tolerance to divalent cations P divalent cation tolerance protein, conjectural 1.483333 3.222690 1.0785096 3635 Predicted phosphoglycerate mutase, AP superfamily G phosphonopyruvate decarboxylase, conjectural 1.116692e-01 17 2.010590e-02 5.549212e-03 1.155857e-02 3.552437e-01 2.612520e-01 0 22 17 TRUE TRUE 115 TRUE 0.4469764 0.2069500 0.5480306 0.4469764 0.7782882 1.0486335 0.6147754 0.5572152 N 0.5492530 0.5365404 13773 129 183613 183614 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.483333 3.222690 1.0785096 3635 Predicted phosphoglycerate mutase, AP superfamily G phosphonopyruvate decarboxylase, conjectural 1.482257 3.275173 1.0596085 - - - hypothetical protein 0.000000e+00 0 1.158335e-06 9.858205e-04 3.209252e-02 1.504810e-01 9.954005e-05 17 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5306664 0.6550803 U 0.4686274 0.6162291 13773 129 183614 183615 1 -44 Convergent + - 0.000000 0 0.000000 0.00000000 1.482257 3.275173 1.0596085 - - - hypothetical protein 1.512158 3.211057 1.0419126 1634 Uncharacterized Rossmann fold enzyme R conserved hypothetical protein 0.000000e+00 0 8.940924e-04 1.875486e-03 4.962430e-02 2.210190e-01 3.770094e-02 0 0 TRUE TRUE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5576688 0.6287554 U 0.4686274 0.6162291 13773 129 183615 183616 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.512158 3.211057 1.0419126 1634 Uncharacterized Rossmann fold enzyme R conserved hypothetical protein 1.482887 3.643801 1.2136475 477 Permeases of the major facilitator superfamily GEPR sugar transporter, conjectural 0.000000e+00 0 8.567950e-04 1.913788e-03 3.625615e-02 2.227907e-01 3.651824e-02 0 27 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5583920 0.6293389 U 0.4686274 0.6162291 13773 129 183616 183617 1 254 Same - - 0.000000 0 0.000000 -0.15028220 1.482887 3.643801 1.2136475 477 Permeases of the major facilitator superfamily GEPR sugar transporter, conjectural 1.477978 3.235548 1.0852840 1650 Uncharacterized protein conserved in archaea S conserved hypothetical protein 7.917166e-03 3 2.410317e-05 8.372858e-04 2.980335e-02 1.345039e-01 1.414176e-03 27 3 FALSE TRUE 115 TRUE 0.4469764 0.2771315 0.5480306 0.4469764 0.7136133 0.5787144 0.5261933 0.6511912 U 0.4686274 0.5499469 13773 129 183617 183618 1 13 Same - - 0.000000 0 0.000000 -0.20585205 1.477978 3.235548 1.0852840 1650 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.511422 3.291047 1.1093933 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.841759e-02 3 1.118498e-03 1.595876e-03 4.675336e-02 1.997504e-01 5.056458e-02 3 17 FALSE TRUE 114 TRUE 0.4469764 0.2710905 0.5480306 0.4469764 0.7136133 0.6663050 0.5499731 0.6236602 U 0.4686274 0.5480411 13773 129 183618 183619 1 -3 Same - - 2.856470 0 5.519058 4.35916876 1.511422 3.291047 1.1093933 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.496062 3.245016 1.0706130 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ medium-chain acyl-CoA ligase 1.116560e-03 17 2.359304e-04 2.681436e-03 4.800585e-02 2.749868e-01 8.766593e-03 17 24 FALSE TRUE 113 TRUE 2.8950318 1.7520176 0.5480306 2.8617306 0.7782882 0.4733125 0.5825759 0.6436550 U 0.4686274 0.8552180 13773 129 183619 183620 1 87 Divergent - + 0.000000 0 0.000000 -2.05010507 1.496062 3.245016 1.0706130 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ medium-chain acyl-CoA ligase 1.475558 3.096341 1.0450955 624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases E possible succinyl-diaminopimelate desuccinylase 6.763448e-02 24 4.204270e-04 1.079412e-03 2.977425e-02 1.560835e-01 2.379596e-02 24 43 FALSE TRUE 112 FALSE 0.4469764 0.1958623 0.5480306 0.4469764 0.7769228 0.9064426 0.5328084 0.6358881 U 0.4686274 0.5242084 13773 129 183620 183621 1 -10 Convergent + - 0.000000 0 0.000000 -0.04255961 1.475558 3.096341 1.0450955 624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases E possible succinyl-diaminopimelate desuccinylase 1.517349 3.382219 1.1362221 778 Nitroreductase C conserved hypothetical protein 3.702577e-04 2 1.746513e-03 1.593805e-03 4.893736e-02 1.967901e-01 7.803940e-02 0 43 2 TRUE TRUE 113 FALSE 0.4469764 0.3082875 0.5480306 0.4469764 0.6838149 0.4473591 0.5485227 0.6154327 N 0.5492530 0.5684521 13773 129 183621 183622 1 6 Divergent - + 0.000000 0 0.000000 0.00000000 1.517349 3.382219 1.1362221 778 Nitroreductase C conserved hypothetical protein 1.427334 3.503229 1.1485988 - - - hypothetical protein 0.000000e+00 0 8.102656e-03 -1.586820e-03 -7.393273e-03 -8.911250e-02 5.656702e-01 2 0 FALSE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4955506 0.4818106 U 0.4686274 0.6162291 13773 129 183622 183623 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.427334 3.503229 1.1485988 - - - hypothetical protein 1.473164 3.222187 1.0513741 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H ubiquinone/menaquinone biosynthesis methyltransferase (ubiE), conjectural 0.000000e+00 0 2.100358e-03 -5.237808e-04 1.434722e-02 -4.353847e-02 1.960933e-01 0 13 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5081483 0.5808669 U 0.4686274 0.6162291 13773 129 183623 183624 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.473164 3.222187 1.0513741 2226 Methylase involved in ubiquinone/menaquinone biosynthesis H ubiquinone/menaquinone biosynthesis methyltransferase (ubiE), conjectural 1.430711 3.100423 1.0737814 - - - P. aerophilum family 577 protein 0.000000e+00 0 1.802271e-03 -4.502715e-04 1.535563e-02 -3.174680e-02 1.623416e-01 13 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5116760 0.5894844 U 0.4686274 0.6162291 13773 129 183624 183625 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.430711 3.100423 1.0737814 - - - P. aerophilum family 577 protein 1.369161 3.048681 1.0740449 - - - P. aerophilum family 562 protein 0.000000e+00 0 3.788379e-03 1.700747e-03 5.670946e-02 7.149214e-02 3.113006e-01 0 0 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180253 0.5379312 U 0.4686274 0.6162291 13773 129 183625 183626 1 42 Same - - 0.000000 0 0.000000 0.00000000 1.369161 3.048681 1.0740449 - - - P. aerophilum family 562 protein 1.592004 3.489508 1.0977187 - - - hypothetical protein 0.000000e+00 0 4.965892e-02 -1.156271e-02 -8.141966e-02 -5.678519e-01 2.306762e+00 0 0 FALSE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3970660 0.4050462 U 0.4686274 0.6162291 13773 129 183626 183627 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.592004 3.489508 1.0977187 - - - hypothetical protein 1.468302 3.287342 1.0594303 - - - hypothetical protein 0.000000e+00 0 1.530216e-02 2.377564e-03 -9.466787e-04 2.148275e-01 3.620289e-01 0 0 FALSE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5553645 0.5204865 U 0.4686274 0.6162291 13773 129 183627 183628 1 200 Divergent - + 0.000000 0 0.000000 0.00000000 1.468302 3.287342 1.0594303 - - - hypothetical protein 1.494562 3.356862 1.1028924 - - - hypothetical protein 0.000000e+00 0 6.896281e-04 7.299481e-04 3.327905e-02 1.184256e-01 4.784107e-02 0 0 FALSE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5217688 0.6247981 U 0.4686274 0.6162291 13773 129 183628 183629 1 -29 Convergent + - 0.000000 0 0.000000 0.00000000 1.494562 3.356862 1.1028924 - - - hypothetical protein 1.562935 3.640498 1.1831172 2860 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 4.674834e-03 4.815241e-03 1.039020e-01 3.700799e-01 9.997827e-02 0 2 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6198316 0.6068453 U 0.4686274 0.6162291 13773 129 183629 183630 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.562935 3.640498 1.1831172 2860 Predicted membrane protein S conserved hypothetical protein 1.429972 3.154705 1.0329476 - - - hypothetical protein 0.000000e+00 0 1.767935e-02 -2.389386e-03 -3.763017e-02 -9.297277e-02 8.187264e-01 2 0 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4945325 0.4531269 U 0.4686274 0.6162291 13773 129 183630 183631 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.429972 3.154705 1.0329476 - - - hypothetical protein 1.472577 3.369668 1.1166873 - - - conserved hypothetical protein 0.000000e+00 0 1.815200e-03 -4.537858e-04 1.540620e-02 -3.419584e-02 1.660735e-01 0 0 FALSE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5107526 0.5884564 U 0.4686274 0.6162291 13773 129 183631 183632 1 62 Same - - 0.000000 0 0.000000 0.00000000 1.472577 3.369668 1.1166873 - - - conserved hypothetical protein 1.438154 3.095842 1.0848479 1245 Predicted ATPase, RNase L inhibitor (RLI) homolog R RNase L inhibitor homolog 0.000000e+00 0 1.184899e-03 -2.804429e-04 1.676413e-02 -1.021434e-02 1.053882e-01 0 12 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185854 0.6043969 U 0.4686274 0.6162291 13773 129 183632 183633 1 124 Same - - 0.000000 0 0.000000 0.00000000 1.438154 3.095842 1.0848479 1245 Predicted ATPase, RNase L inhibitor (RLI) homolog R RNase L inhibitor homolog 1.374307 3.463428 1.1698463 - - - hypothetical protein 0.000000e+00 0 4.076533e-03 1.020509e-03 4.731520e-02 2.237943e-02 3.583442e-01 12 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175169 0.5224252 U 0.4686274 0.6162291 13773 129 183633 183634 1 -9 Same - - 0.000000 0 0.000000 0.00000000 1.374307 3.463428 1.1698463 - - - hypothetical protein 1.515689 3.423986 1.1618010 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase 0.000000e+00 0 1.998901e-02 -4.956356e-03 -4.180558e-02 -3.794773e-01 1.519156e+00 0 3 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4233094 0.4165262 U 0.4686274 0.6162291 13773 129 183634 183635 1 132 Divergent - + 0.000000 0 0.000000 0.00000000 1.515689 3.423986 1.1618010 1215 Glycosyltransferases, probably involved in cell wall biogenesis M glycosyl transferase 1.491588 3.207671 1.0700211 - - - hypothetical protein 0.000000e+00 0 5.808735e-04 2.584381e-03 4.455956e-02 2.705958e-01 2.148710e-02 3 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5797242 0.6369087 U 0.4686274 0.6162291 13773 129 183635 183636 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.491588 3.207671 1.0700211 - - - hypothetical protein 1.466773 3.075976 0.9839308 - - - hypothetical protein 0.000000e+00 0 6.157638e-04 6.182107e-04 2.446381e-02 1.078914e-01 4.551984e-02 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196537 0.6257919 U 0.4686274 0.6162291 13773 129 183636 183637 1 -12 Convergent + - 0.000000 0 0.000000 0.00000000 1.466773 3.075976 0.9839308 - - - hypothetical protein 1.519315 3.344217 1.0823030 - - - hypothetical protein 0.000000e+00 0 2.760661e-03 1.044667e-03 4.406737e-02 1.470913e-01 1.425743e-01 0 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5298704 0.5949759 U 0.4686274 0.6162291 13773 129 183637 183638 1 40 Divergent - + 0.000000 0 0.000000 0.00000000 1.519315 3.344217 1.0823030 - - - hypothetical protein 1.458476 3.205468 1.0436440 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar phospate transferase 0.000000e+00 0 3.701385e-03 4.811145e-04 1.477456e-02 9.932213e-02 2.071193e-01 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185803 0.5774877 U 0.4686274 0.6162291 13773 129 183638 183639 1 -23 Convergent + - 0.000000 0 0.000000 0.00000000 1.458476 3.205468 1.0436440 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar phospate transferase 1.439600 3.186784 1.1265130 1201 Lhr-like helicases R ATP-dependent helicase 0.000000e+00 0 3.563003e-04 -8.353068e-05 1.998677e-02 -2.226399e-03 3.061829e-02 0 13 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199212 0.6326945 U 0.4686274 0.6162291 13773 129 183639 183640 1 60 Divergent - + 0.000000 0 0.000000 0.00000000 1.439600 3.186784 1.1265130 1201 Lhr-like helicases R ATP-dependent helicase 1.517611 3.528935 1.1186482 - - - hypothetical protein 0.000000e+00 0 6.085733e-03 -7.808890e-04 2.238962e-02 -8.386102e-03 3.854856e-01 13 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191396 0.5151711 U 0.4686274 0.6162291 13773 129 183640 183641 1 -26 Convergent + - 0.000000 0 0.000000 0.00000000 1.517611 3.528935 1.1186482 - - - hypothetical protein 1.469492 3.151542 1.0612632 517 FOG: CBS domain R conserved protein with 4 CBS domains 0.000000e+00 0 2.315482e-03 1.198491e-03 2.444720e-02 1.630631e-01 1.145482e-01 0 9 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5356723 0.6020917 U 0.4686274 0.6162291 13773 129 183641 183642 1 17 Same - - 0.000000 0 0.000000 -0.70116330 1.469492 3.151542 1.0612632 517 FOG: CBS domain R conserved protein with 4 CBS domains 1.512155 3.145248 1.0474880 127 Xanthosine triphosphate pyrophosphatase F nucleoside-triphosphatase (NTPase) 3.891653e-02 9 1.820131e-03 1.099734e-03 4.214014e-02 1.548172e-01 9.471089e-02 9 55 FALSE TRUE 106 TRUE 0.4469764 0.2250311 0.5480306 0.4469764 0.7702221 0.8007956 0.5320016 0.6088875 U 0.4686274 0.5334684 13773 129 183642 183643 1 0 Same - - 0.000000 0 0.000000 -0.77117342 1.512155 3.145248 1.0474880 127 Xanthosine triphosphate pyrophosphatase F nucleoside-triphosphatase (NTPase) 1.424281 3.010410 1.0664221 526 Thiol-disulfide isomerase and thioredoxins OC glutaredoxin-like protein 2.973966e-02 7 7.721849e-03 -1.647382e-03 -6.033190e-03 -1.043910e-01 5.737801e-01 55 7 FALSE TRUE 105 TRUE 0.4469764 0.2198448 0.5480306 0.4469764 0.7596462 0.7322295 0.4898862 0.4809145 U 0.4686274 0.5318235 13773 129 183643 183644 1 25 Same - - 0.000000 0 0.000000 0.00000000 1.424281 3.010410 1.0664221 526 Thiol-disulfide isomerase and thioredoxins OC glutaredoxin-like protein 1.376081 2.841700 0.9758487 - - - hypothetical protein 0.000000e+00 0 2.323203e-03 2.041851e-03 5.714858e-02 1.125922e-01 1.940595e-01 7 0 FALSE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5202559 0.5817361 U 0.4686274 0.6162291 13773 129 183644 183645 1 28 Same - - 0.000000 0 0.000000 0.00000000 1.376081 2.841700 0.9758487 - - - hypothetical protein 1.432814 3.220111 1.0798073 39 Malate/lactate dehydrogenases C malate dehydrogenase 0.000000e+00 0 3.218583e-03 1.399221e-03 2.357068e-02 4.866272e-02 2.952417e-01 0 54 FALSE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187637 0.5436061 U 0.4686274 0.6162291 13773 129 183645 183646 1 68 Same - - 1.791759 0 11.184421 2.15314922 1.432814 3.220111 1.0798073 39 Malate/lactate dehydrogenases C malate dehydrogenase 1.516560 3.245041 1.1284345 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R NADH oxidase (nox) 5.869990e-02 39 7.013403e-03 -1.210743e-03 1.648937e-02 -4.716078e-02 4.634025e-01 54 39 FALSE TRUE 102 TRUE 2.9327734 1.6698372 0.5480306 2.7240699 0.7736367 0.8789942 0.5072577 0.5009016 U 0.4686274 0.8411407 13773 129 183646 183647 1 329 Same - - 0.000000 0 0.000000 0.00000000 1.516560 3.245041 1.1284345 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R NADH oxidase (nox) 1.305292 2.920667 1.1052237 - - - hypothetical protein 0.000000e+00 0 4.463402e-02 -9.520939e-03 -4.716157e-02 -5.613058e-01 2.353622e+00 39 0 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3979894 0.4044878 U 0.4686274 0.6162291 13773 129 183647 183648 1 73 Divergent - + 0.000000 0 0.000000 0.00000000 1.305292 2.920667 1.1052237 - - - hypothetical protein 1.425093 3.322647 1.1375384 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H 4-hydroxybenzoate octaprenyltransferase (ubiA) 0.000000e+00 0 1.435214e-02 3.842485e-03 1.321485e-02 1.601688e-01 5.772734e-01 0 7 FALSE TRUE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5347102 0.4802448 U 0.4686274 0.6162291 13773 129 183648 183649 1 -61 Convergent + - 0.000000 0 0.000000 0.00000000 1.425093 3.322647 1.1375384 382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases H 4-hydroxybenzoate octaprenyltransferase (ubiA) 1.555036 3.779359 1.2331522 477 Permeases of the major facilitator superfamily GEPR drug resistance protein, conjectural 0.000000e+00 0 1.688535e-02 -2.725848e-03 1.438900e-02 -1.311431e-01 8.737873e-01 7 0 TRUE TRUE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4812531 0.4485115 U 0.4686274 0.6162291 13773 129 183649 183650 1 -40 Same - - 0.000000 0 0.000000 0.00000000 1.555036 3.779359 1.2331522 477 Permeases of the major facilitator superfamily GEPR drug resistance protein, conjectural 1.514465 3.182476 1.0378620 97 Ribosomal protein L6P/L9E J ribosomal protein L6 0.000000e+00 0 1.646060e-03 6.536965e-03 7.999271e-02 4.490482e-01 3.035029e-02 0 52 FALSE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6554013 0.6329638 U 0.4686274 0.6162291 13773 129 183650 183651 1 67 Same - - 0.000000 0 0.000000 0.00000000 1.514465 3.182476 1.0378620 97 Ribosomal protein L6P/L9E J ribosomal protein L6 1.479216 3.428924 1.1334820 2096 Uncharacterized conserved protein S conserved within P. aerophilum 0.000000e+00 0 1.242427e-03 1.754885e-03 3.312000e-02 2.114231e-01 5.265669e-02 52 0 FALSE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5538092 0.6230318 U 0.4686274 0.6162291 13773 129 183651 183652 1 16 Same - - 0.000000 0 0.000000 0.00000000 1.479216 3.428924 1.1334820 2096 Uncharacterized conserved protein S conserved within P. aerophilum 1.695917 3.869801 1.1710040 - - - hypothetical protein 0.000000e+00 0 4.695931e-02 6.803565e-03 2.501640e-01 3.475939e-01 3.703885e-01 0 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6117416 0.5182644 U 0.4686274 0.6162291 13773 129 183652 183653 1 267 Divergent - + 0.000000 0 0.000000 0.00000000 1.695917 3.869801 1.1710040 - - - hypothetical protein 1.771508 3.741201 1.0540512 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 5.713971e-03 7.827610e-02 1.044354e+00 9.543977e-01 3.392608e-04 0 2 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8124037 0.6537679 U 0.4686274 0.6162291 13773 129 183653 183654 1 29 Same + + 0.000000 0 0.000000 -0.07232066 1.771508 3.741201 1.0540512 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.459084 3.298383 1.0691251 589 Universal stress protein UspA and related nucleotide-binding proteins T universal stress protein family 9.161747e-05 2 9.760885e-02 2.462095e-03 -2.105579e-01 1.665087e-01 6.680522e-01 2 34 TRUE TRUE 98 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6838149 0.4402366 0.5373414 0.4691571 U 0.4686274 0.5573725 13773 129 183654 183655 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.459084 3.298383 1.0691251 589 Universal stress protein UspA and related nucleotide-binding proteins T universal stress protein family 1.569391 3.823999 1.1999919 477 Permeases of the major facilitator superfamily GEPR transport protein part 2, authentic frameshift 0.000000e+00 0 1.216766e-02 9.075581e-04 6.655806e-02 1.356690e-01 4.028304e-01 34 0 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5267157 0.5119762 U 0.4686274 0.6162291 13773 129 183655 183656 1 -69 Same - - 0.000000 0 0.000000 0.00000000 1.569391 3.823999 1.1999919 477 Permeases of the major facilitator superfamily GEPR transport protein part 2, authentic frameshift 1.459393 3.597965 1.1903404 477 Permeases of the major facilitator superfamily GEPR transport protein part 1, authentic frameshift 0.000000e+00 0 1.209965e-02 9.439869e-04 -3.421594e-03 1.406024e-01 3.950745e-01 0 0 FALSE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5277629 0.5132117 U 0.4686274 0.6162291 13773 129 183656 183657 1 78 Divergent - + 0.000000 0 0.000000 0.00000000 1.459393 3.597965 1.1903404 477 Permeases of the major facilitator superfamily GEPR transport protein part 1, authentic frameshift 1.472557 3.348191 1.1226351 - - - hypothetical protein 0.000000e+00 0 1.732824e-04 1.693093e-04 2.369222e-02 5.049331e-02 1.290133e-02 0 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187852 0.6415107 U 0.4686274 0.6162291 13773 129 183657 183658 1 -32 Convergent + - 0.000000 0 0.000000 0.00000000 1.472557 3.348191 1.1226351 - - - hypothetical protein 1.470000 3.677709 1.1989149 730 Predicted permeases R hypothetical protein 0.000000e+00 0 6.535574e-06 3.937966e-04 2.508387e-02 7.817605e-02 3.115780e-04 0 0 TRUE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178115 0.6539188 U 0.4686274 0.6162291 13773 129 183658 183659 1 106 Divergent - + 0.000000 0 0.000000 0.00000000 1.470000 3.677709 1.1989149 730 Predicted permeases R hypothetical protein 1.370935 3.273790 1.1055506 4023 Preprotein translocase subunit Sec61beta U hypothetical protein 0.000000e+00 0 9.813947e-03 -1.497101e-03 1.879347e-02 -1.775594e-01 8.580759e-01 0 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4713080 0.4495188 U 0.4686274 0.6162291 13773 129 183659 183660 1 177 Same + + 0.000000 0 0.000000 0.00000000 1.370935 3.273790 1.1055506 4023 Preprotein translocase subunit Sec61beta U hypothetical protein 1.346098 3.066685 1.0732087 747 ABC-type dipeptide transport system, periplasmic component E dipeptide binding protein 0.000000e+00 0 6.168577e-04 8.471827e-03 1.315086e-01 5.271453e-01 2.216739e-02 0 0 50 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6870455 0.6366745 N 0.5492530 0.6245624 13773 129 183660 183661 1 -3 Convergent + - 14.897927 0 31.003127 29.06991464 1.346098 3.066685 1.0732087 747 ABC-type dipeptide transport system, periplasmic component E dipeptide binding protein 1.421756 3.425595 1.1676432 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide transport permease 2.388100e-02 19 5.724136e-03 3.120597e-03 3.129962e-02 1.672791e-01 3.555930e-01 50 19 TRUE TRUE 99 FALSE 2.5753743 1.9636520 0.5480306 2.4003631 0.7779521 0.7002468 0.5376222 0.5235224 U 0.4686274 0.8894766 13773 129 183661 183662 1 0 Same - - 23.483782 0 33.179630 31.36760758 1.421756 3.425595 1.1676432 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide transport permease 1.451773 3.475871 1.1937884 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide transport permease 3.274588e-02 19 9.010343e-04 -1.127570e-05 1.837567e-02 -2.059066e-02 9.423910e-02 19 43 FALSE TRUE 98 TRUE 2.2720708 1.9807008 0.5480306 2.3586192 0.7779521 0.7555347 0.5152182 0.6091015 U 0.4686274 0.8951754 13773 129 183662 183663 1 528 Divergent - + 0.000000 0 0.000000 0.00000000 1.451773 3.475871 1.1937884 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP dipeptide transport permease 1.525744 3.272221 1.0555162 - - - hypothetical protein 0.000000e+00 0 5.471736e-03 2.828805e-05 3.510690e-02 6.465922e-02 3.070334e-01 43 0 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182816 0.5396610 U 0.4686274 0.6162291 13773 129 183663 183664 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.525744 3.272221 1.0555162 - - - hypothetical protein 1.478384 3.214759 1.0623518 - - - hypothetical protein 0.000000e+00 0 2.243004e-03 2.006846e-03 3.201358e-02 2.305677e-01 9.004605e-02 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5619239 0.6109629 U 0.4686274 0.6162291 13773 129 183664 183665 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.478384 3.214759 1.0623518 - - - hypothetical protein 1.419556 3.190131 1.0407502 - - - hypothetical protein 0.000000e+00 0 3.460706e-03 -8.593075e-04 1.141427e-02 -7.857185e-02 3.313094e-01 0 0 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4984120 0.5307106 U 0.4686274 0.6162291 13773 129 183665 183666 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.419556 3.190131 1.0407502 - - - hypothetical protein 1.429069 3.141549 1.0353367 455 ATPases involved in chromosome partitioning D hypothetical protein 0.000000e+00 0 9.049389e-05 7.107066e-04 2.773907e-02 2.818338e-02 9.203038e-03 0 0 TRUE TRUE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173819 0.6433585 U 0.4686274 0.6162291 13773 129 183666 183667 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.429069 3.141549 1.0353367 455 ATPases involved in chromosome partitioning D hypothetical protein 1.343783 3.005146 1.0545143 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU type II secretion system protein, conjectural 0.000000e+00 0 7.273687e-03 2.402239e-03 7.696684e-02 1.032095e-01 4.739102e-01 0 0 TRUE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190548 0.4977420 U 0.4686274 0.6162291 13773 129 183667 183668 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.343783 3.005146 1.0545143 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU type II secretion system protein, conjectural 1.350746 3.159619 1.0787493 - - - hypothetical protein 0.000000e+00 0 4.848377e-05 1.083053e-02 1.436888e-01 6.292651e-01 1.847086e-03 0 0 TRUE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7284947 0.6505622 U 0.4686274 0.6162291 13773 129 183668 183669 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.350746 3.159619 1.0787493 - - - hypothetical protein 1.361390 3.100535 1.1110331 - - - hypothetical protein 0.000000e+00 0 1.132842e-04 9.058494e-03 1.214990e-01 5.516439e-01 3.313094e-03 0 0 TRUE TRUE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7000423 0.6480385 U 0.4686274 0.6162291 13773 129 183669 183670 1 47 Same + + 0.000000 0 0.000000 0.00000000 1.361390 3.100535 1.1110331 - - - hypothetical protein 1.359462 3.218214 1.0872858 - - - hypothetical protein 0.000000e+00 0 3.717144e-06 8.274071e-03 1.183712e-01 5.176460e-01 9.954005e-05 0 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6822277 0.6550803 U 0.4686274 0.6162291 13773 129 183670 183671 1 54 Same + + 0.000000 0 0.000000 0.00000000 1.359462 3.218214 1.0872858 - - - hypothetical protein 1.456950 3.364923 1.1801270 - - - hypothetical protein 0.000000e+00 0 9.503986e-03 -5.108945e-04 -6.619585e-03 -1.073101e-01 7.614337e-01 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4886155 0.4584148 U 0.4686274 0.6162291 13773 129 183671 183672 1 59 Same + + 0.000000 0 0.000000 0.00000000 1.456950 3.364923 1.1801270 - - - hypothetical protein 1.338310 3.035230 1.0370695 - - - hypothetical protein 0.000000e+00 0 1.407547e-02 -6.284422e-04 4.578581e-02 -1.247025e-01 9.801456e-01 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4835508 0.4412509 U 0.4686274 0.6162291 13773 129 183672 183673 1 50 Same + + 0.000000 0 0.000000 0.00000000 1.338310 3.035230 1.0370695 - - - hypothetical protein 1.439287 3.500006 1.1677627 - - - hypothetical protein 0.000000e+00 0 1.019623e-02 1.369016e-03 4.642335e-03 1.292254e-02 6.831917e-01 0 0 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184236 0.4664146 U 0.4686274 0.6162291 13773 129 183673 183674 1 -15 Same + + 0.000000 0 0.000000 0.00000000 1.439287 3.500006 1.1677627 - - - hypothetical protein 1.385836 2.974963 0.9991273 - - - hypothetical protein 0.000000e+00 0 2.856988e-03 7.936560e-04 4.055928e-02 8.363721e-03 2.804202e-01 0 0 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190690 0.5510159 U 0.4686274 0.6162291 13773 129 183674 183675 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.385836 2.974963 0.9991273 - - - hypothetical protein 1.426349 3.185126 1.1086859 - - - hypothetical protein 0.000000e+00 0 1.641345e-03 1.641787e-03 3.061252e-02 8.530995e-02 1.508038e-01 0 0 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176826 0.5929737 U 0.4686274 0.6162291 13773 129 183675 183676 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.426349 3.185126 1.1086859 - - - hypothetical protein 1.340649 2.933286 1.0136987 - - - hypothetical protein 0.000000e+00 0 7.344519e-03 2.773424e-03 8.271761e-02 1.296471e-01 4.509488e-01 0 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5240737 0.5035785 U 0.4686274 0.6162291 13773 129 183676 183677 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.340649 2.933286 1.0136987 - - - hypothetical protein 1.407212 3.111002 1.1032309 - - - hypothetical protein 0.000000e+00 0 4.430673e-03 4.892712e-03 5.175655e-02 2.777244e-01 2.427623e-01 0 0 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5837754 0.5650312 U 0.4686274 0.6162291 13773 129 183677 183678 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.407212 3.111002 1.1032309 - - - hypothetical protein 1.502961 3.417446 1.1390219 - - - hypothetical protein 0.000000e+00 0 9.167742e-03 -2.278292e-03 -4.104471e-03 -1.757977e-01 7.388346e-01 0 0 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4715751 0.4609040 U 0.4686274 0.6162291 13773 129 183678 183679 1 197 Same + + 0.000000 0 0.000000 0.00000000 1.502961 3.417446 1.1390219 - - - hypothetical protein 1.377863 3.163707 1.0778806 - - - hypothetical protein 0.000000e+00 0 1.564947e-02 -3.791784e-03 -1.661982e-02 -3.157923e-01 1.269297e+00 0 0 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4360885 0.4255677 U 0.4686274 0.6162291 13773 129 183679 183680 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.377863 3.163707 1.0778806 - - - hypothetical protein 1.410998 3.040329 1.0210129 - - - hypothetical protein 0.000000e+00 0 1.097965e-03 2.970202e-03 4.587961e-02 1.835572e-01 8.866957e-02 0 0 TRUE TRUE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5434213 0.6116373 U 0.4686274 0.6162291 13773 129 183680 183681 1 55 Convergent + - 0.000000 0 0.000000 0.00000000 1.410998 3.040329 1.0210129 - - - hypothetical protein 1.538403 3.472078 1.1461646 1602 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.623199e-02 -3.514736e-03 -5.275188e-03 -2.155920e-01 1.024709e+00 0 3 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4602820 0.4374432 U 0.4686274 0.6162291 13773 129 183681 183682 1 28 Same - - 0.000000 0 0.000000 -0.26504093 1.538403 3.472078 1.1461646 1602 Uncharacterized conserved protein S conserved hypothetical protein 1.483817 3.350480 1.1156986 626 Cystathionine beta-lyases/cystathionine gamma-synthases E cystathionine gamma-synthase 1.308803e-02 3 2.979633e-03 2.821259e-03 3.716839e-02 2.818444e-01 9.565799e-02 3 54 FALSE TRUE 114 TRUE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.6246374 0.5849816 0.6084549 U 0.4686274 0.5447277 13773 129 183682 183683 1 189 Divergent - + 0.000000 0 0.000000 -0.17185026 1.483817 3.350480 1.1156986 626 Cystathionine beta-lyases/cystathionine gamma-synthases E cystathionine gamma-synthase 1.497988 3.320684 1.0433806 569 K+ transport systems, NAD-binding component P potassium transport peripheral protein, conjectural 3.305270e-03 2 2.008178e-04 1.510828e-03 4.124643e-02 1.974745e-01 9.499891e-03 0 54 2 FALSE TRUE 113 FALSE 0.4469764 0.2758904 0.5480306 0.4469764 0.6838149 0.5221400 0.5491640 0.6431205 N 0.5492530 0.5582988 13773 129 183683 183684 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.497988 3.320684 1.0433806 569 K+ transport systems, NAD-binding component P potassium transport peripheral protein, conjectural 1.469167 3.264247 1.0894773 - - - potassium transport membrane protein, conjectural 0.000000e+00 0 8.306564e-04 8.282009e-04 2.570993e-02 1.305082e-01 5.407499e-02 2 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5241888 0.6225521 U 0.4686274 0.6162291 13773 129 183684 183685 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.469167 3.264247 1.0894773 - - - potassium transport membrane protein, conjectural 1.450203 3.118907 1.0997703 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G phosphoenolpyruvate synthase (pyruvate,water dikinase) 0.000000e+00 0 3.596529e-04 -2.115523e-05 1.969164e-02 2.282883e-02 3.115780e-02 0 24 FALSE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174875 0.6322033 U 0.4686274 0.6162291 13773 129 183685 183686 1 126 Same - - 0.000000 0 0.000000 0.00000000 1.450203 3.118907 1.0997703 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G phosphoenolpyruvate synthase (pyruvate,water dikinase) 1.512373 3.246166 1.0771876 - - - hypothetical protein 0.000000e+00 0 3.865190e-03 -7.257980e-05 2.932892e-02 5.018350e-02 2.420066e-01 24 0 FALSE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187805 0.5652310 U 0.4686274 0.6162291 13773 129 183686 183687 1 67 Divergent - + 0.000000 0 0.000000 0.00000000 1.512373 3.246166 1.0771876 - - - hypothetical protein 1.402932 3.108366 1.0828631 1032 Fe-S oxidoreductase C conserved hypothetical protein 0.000000e+00 0 1.197743e-02 -2.955174e-03 -1.729452e-02 -2.242714e-01 9.336038e-01 0 8 FALSE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4583151 0.4442659 U 0.4686274 0.6162291 13773 129 183687 183688 1 -39 Convergent + - 0.000000 0 0.000000 0.00000000 1.402932 3.108366 1.0828631 1032 Fe-S oxidoreductase C conserved hypothetical protein 1.482986 3.194584 1.1320022 - - - hypothetical protein 0.000000e+00 0 6.408672e-03 -1.531037e-03 -5.928272e-04 -1.508032e-01 6.032151e-01 8 0 TRUE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4765214 0.4767123 U 0.4686274 0.6162291 13773 129 183688 183689 1 131 Same - - 0.000000 0 0.000000 0.00000000 1.482986 3.194584 1.1320022 - - - hypothetical protein 1.477575 3.351037 1.1299820 - - - hypothetical protein 0.000000e+00 0 2.927468e-05 8.271902e-04 2.961557e-02 1.340805e-01 1.981377e-03 0 0 FALSE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5259324 0.6503033 U 0.4686274 0.6162291 13773 129 183689 183690 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.477575 3.351037 1.1299820 - - - hypothetical protein 1.525357 3.406630 1.1726082 533 Metal-dependent proteases with possible chaperone activity O o-syaloglycoprotein endopeptidase 0.000000e+00 0 2.283128e-03 1.936584e-03 5.553294e-02 2.242608e-01 9.376850e-02 0 63 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5589390 0.6094409 U 0.4686274 0.6162291 13773 129 183690 183691 1 1 Same - - 7.575243 0 7.575243 7.57524271 1.525357 3.406630 1.1726082 533 Metal-dependent proteases with possible chaperone activity O o-syaloglycoprotein endopeptidase 1.284528 2.673174 1.0148683 1998 Ribosomal protein S27AE J ribosomal protein S27 6.672049e-03 3 5.799888e-02 -1.234211e-02 -6.675290e-02 -6.308271e-01 2.624748e+00 0 63 3 FALSE TRUE 109 TRUE 2.7217601 1.8131776 0.5480306 2.8161013 0.7136133 0.5663031 0.3912435 0.4026225 N 0.5492530 0.8711225 13773 129 183691 183692 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.284528 2.673174 1.0148683 1998 Ribosomal protein S27AE J ribosomal protein S27 1.452505 3.088854 1.0535606 2004 Ribosomal protein S24E J ribosomal protein S24 0.000000e+00 0 2.821629e-02 -1.855758e-04 -5.213881e-02 -1.056338e-01 1.162690e+00 J 3 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4891942 0.4300663 Y 1.4497162 0.7118045 13773 129 183692 183693 1 46 Same - - 0.000000 0 0.000000 0.00000000 1.452505 3.088854 1.0535606 2004 Ribosomal protein S24E J ribosomal protein S24 1.456920 3.361264 1.0652496 3431 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 1.949173e-05 6.146837e-06 2.088400e-02 1.605834e-02 1.472486e-03 0 0 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181137 0.6510547 U 0.4686274 0.6162291 13773 129 183693 183694 1 251 Divergent - + 0.000000 0 0.000000 0.00000000 1.456920 3.361264 1.0652496 3431 Predicted membrane protein S conserved hypothetical protein 1.416426 3.150113 1.1025380 1032 Fe-S oxidoreductase C conserved hypothetical protein 0.000000e+00 0 1.639732e-03 -1.932626e-04 2.150538e-02 -3.697942e-02 1.586521e-01 0 17 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5098258 0.5904345 U 0.4686274 0.6162291 13773 129 183694 183695 1 -23 Convergent + - 0.000000 0 0.000000 0.00000000 1.416426 3.150113 1.1025380 1032 Fe-S oxidoreductase C conserved hypothetical protein 1.540431 3.574595 1.1666871 1266 Predicted metal-dependent membrane protease R conserved within P. aerophilum 0.000000e+00 0 1.537721e-02 -3.113362e-03 1.363233e-03 -1.795043e-01 9.336038e-01 17 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4709062 0.4442659 U 0.4686274 0.6162291 13773 129 183695 183696 1 183 Divergent - + 0.000000 0 0.000000 0.00000000 1.540431 3.574595 1.1666871 1266 Predicted metal-dependent membrane protease R conserved within P. aerophilum 1.438990 3.297355 1.0846338 598 Mg2+ and Co2+ transporters P hypothetical protein 0.000000e+00 0 1.029038e-02 -1.104354e-03 -1.191685e-02 -1.866405e-02 5.496237e-01 0 0 FALSE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5157691 0.4836874 U 0.4686274 0.6162291 13773 129 183696 183697 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.438990 3.297355 1.0846338 598 Mg2+ and Co2+ transporters P hypothetical protein 1.437875 3.111696 1.0926482 2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog E ornithine cyclodeaminase (arcB) 0.000000e+00 0 1.242485e-06 1.676631e-04 2.277143e-02 9.812647e-04 1.325237e-04 0 0 15 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198978 0.6548417 N 0.5492530 0.6245624 13773 129 183697 183698 1 -9 Same + + 0.000000 0 0.000000 -0.60578367 1.437875 3.111696 1.0926482 2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog E ornithine cyclodeaminase (arcB) 1.463702 3.176982 1.1076323 1061 DNA or RNA helicases of superfamily II KL helicase, possible DNA repair 9.572191e-02 10 6.670356e-04 -1.663937e-04 1.871290e-02 -7.965560e-03 6.221253e-02 15 10 TRUE TRUE 108 TRUE 0.4469764 0.2314065 0.5480306 0.4469764 0.7739415 0.9981941 0.5192060 0.6197187 U 0.4686274 0.5354895 13773 129 183698 183699 1 -3 Same + + 19.126115 0 29.985588 29.98558847 1.463702 3.176982 1.1076323 1061 DNA or RNA helicases of superfamily II KL helicase, possible DNA repair 1.395696 3.072886 1.0521069 3372 Uncharacterized conserved protein S conserved hypothetical protein 2.749196e-01 8 4.624783e-03 -6.855814e-04 2.021472e-02 -9.770004e-02 4.530127e-01 10 8 TRUE TRUE 109 TRUE 2.4002074 1.9764282 0.5480306 2.4139043 0.7652913 1.2035108 0.4925009 0.5032088 U 0.4686274 0.8931569 13773 129 183699 183700 1 136 Convergent + - 0.000000 0 0.000000 0.00000000 1.395696 3.072886 1.0521069 3372 Uncharacterized conserved protein S conserved hypothetical protein 1.430758 3.196291 1.1078911 3413 Predicted DNA binding protein R conserved hypothetical protein 0.000000e+00 0 1.229290e-03 1.149314e-03 2.737934e-02 4.920400e-02 1.257173e-01 8 0 TRUE TRUE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187752 0.5994609 U 0.4686274 0.6162291 13773 129 183700 183701 1 103 Divergent - + 0.000000 0 0.000000 0.00000000 1.430758 3.196291 1.1078911 3413 Predicted DNA binding protein R conserved hypothetical protein 1.376764 2.863163 0.9601070 1145 Ferredoxin C ferredoxin 0.000000e+00 0 2.915289e-03 1.539986e-03 5.180593e-02 6.557805e-02 2.581233e-01 0 1 FALSE TRUE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182555 0.5591829 U 0.4686274 0.6162291 13773 129 183701 183702 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.376764 2.863163 0.9601070 1145 Ferredoxin C ferredoxin 1.430986 3.105705 1.0904219 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 7.562104e-04 1 2.940039e-03 1.522918e-03 2.545794e-02 6.369091e-02 2.612520e-01 0 1 4 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5183333 0.5572152 N 0.5492530 0.6245624 13773 129 183702 183703 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.430986 3.105705 1.0904219 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 1.533942 3.477116 1.0589357 - - - paREP13 0.000000e+00 0 1.059995e-02 -1.684554e-03 1.728916e-02 -7.180136e-02 6.346085e-01 4 0 TRUE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5008512 0.4721311 U 0.4686274 0.6162291 13773 129 183703 183704 1 -30 Same - - 0.000000 0 0.000000 0.00000000 1.533942 3.477116 1.0589357 - - - paREP13 1.526805 3.261876 1.0824237 1435 Thymidine kinase F thymidine kinase 0.000000e+00 0 5.094675e-05 6.225204e-03 9.066127e-02 4.579331e-01 1.038986e-03 0 34 FALSE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6597374 0.6518064 U 0.4686274 0.6162291 13773 129 183704 183705 1 17 Same - - 0.000000 0 0.000000 -0.25131443 1.526805 3.261876 1.0824237 1435 Thymidine kinase F thymidine kinase 1.438855 3.569228 1.2269751 1906 Uncharacterized conserved protein S conserved hypothetical protein 9.161747e-05 2 7.735210e-03 -9.455326e-04 -4.360539e-03 -1.774935e-02 4.728541e-01 34 2 FALSE TRUE 109 TRUE 0.4469764 0.2639739 0.5480306 0.4469764 0.6838149 0.4402366 0.5159773 0.4980443 U 0.4686274 0.5457943 13773 129 183705 183706 1 7 Same - - 0.000000 0 0.000000 0.00000000 1.438855 3.569228 1.2269751 1906 Uncharacterized conserved protein S conserved hypothetical protein 1.347890 3.061222 1.0713569 4919 Ribosomal protein S30 J ribosomal protein S30 0.000000e+00 0 8.274491e-03 1.297741e-03 6.271718e-02 2.129509e-02 5.866408e-01 2 0 FALSE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175611 0.4787644 U 0.4686274 0.6162291 13773 129 183706 183707 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.347890 3.061222 1.0713569 4919 Ribosomal protein S30 J ribosomal protein S30 1.391107 2.905490 0.9922133 1720 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.867642e-03 6.239779e-03 7.571945e-02 3.918297e-01 8.912722e-02 0 9 FALSE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6305976 0.6113614 U 0.4686274 0.6162291 13773 129 183707 183708 1 37 Divergent - + 0.000000 0 0.000000 -0.70306007 1.391107 2.905490 0.9922133 1720 Uncharacterized conserved protein S conserved hypothetical protein 1.346898 3.298791 1.1437017 1055 Na+/H+ antiporter NhaD and related arsenite permeases P arsenite transport protein, conjectural 3.145637e-02 9 1.954355e-03 6.299574e-03 1.128935e-01 3.948642e-01 9.283082e-02 9 25 FALSE TRUE 106 FALSE 0.4469764 0.2245661 0.5480306 0.4469764 0.7702221 0.7437618 0.6320924 0.6099430 U 0.4686274 0.5333209 13773 129 183708 183709 1 -7 Convergent + - 0.000000 0 0.000000 -2.96197163 1.346898 3.298791 1.1437017 1055 Na+/H+ antiporter NhaD and related arsenite permeases P arsenite transport protein, conjectural 1.480731 3.309522 1.0854886 159 Tryptophan synthase alpha chain E tryptophan synthase alpha subunit -2.295409e-02 25 1.791104e-02 -3.065633e-03 -4.064985e-02 -2.967613e-01 1.369780e+00 0 25 41 TRUE TRUE 107 FALSE 0.4469764 0.1909211 0.5480306 0.4469764 0.7766777 0.5246940 0.4409471 0.4210285 N 0.5492530 0.5314583 13773 129 183709 183710 1 2 Same - - 23.586704 0 36.152779 32.32719398 1.480731 3.309522 1.0854886 159 Tryptophan synthase alpha chain E tryptophan synthase alpha subunit 1.336639 2.812730 0.9485866 512 Anthranilate/para-aminobenzoate synthases component II EH anthranilate synthase component II 4.806863e-02 41 2.076235e-02 -3.366619e-03 1.262976e-02 -3.152911e-01 1.489037e+00 41 52 FALSE TRUE 106 TRUE 2.2645047 1.9871229 0.5480306 2.3225394 0.7731283 0.8373216 0.4362791 0.4173627 U 0.4686274 0.8960282 13773 129 183710 183711 1 -9 Same - - 15.727291 0 18.389878 18.13791439 1.336639 2.812730 0.9485866 512 Anthranilate/para-aminobenzoate synthases component II EH anthranilate synthase component II 1.431241 3.156608 1.0954557 147 Anthranilate/para-aminobenzoate synthases component I EH anthranilate synthase component I 1.064886e-03 12 8.949432e-03 2.312546e-03 1.536666e-02 8.468562e-02 5.610619e-01 52 12 FALSE TRUE 105 TRUE 2.5478634 1.9007066 0.5480306 2.6315452 0.7776747 0.4717501 0.5176821 0.4821849 U 0.4686274 0.8816988 13773 129 183711 183712 1 -3 Same - - 13.530066 0 16.192654 16.04605033 1.431241 3.156608 1.0954557 147 Anthranilate/para-aminobenzoate synthases component I EH anthranilate synthase component I 1.441490 3.172287 1.0856574 547 Anthranilate phosphoribosyltransferase E anthranilate phosphoribosyltransferase 2.419430e-02 12 1.050423e-04 1.995726e-04 2.228888e-02 -3.062771e-04 1.057598e-02 12 31 FALSE TRUE 104 TRUE 2.6069365 1.8862425 0.5480306 2.6562892 0.7776747 0.7038371 0.5199787 0.6424418 U 0.4686274 0.8789861 13773 129 183712 183713 1 41 Same - - 24.414383 0 46.144461 44.76493847 1.441490 3.172287 1.0856574 547 Anthranilate phosphoribosyltransferase E anthranilate phosphoribosyltransferase 1.384289 3.073505 1.0442475 1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) R tryptophan synthase beta subunit 9.371434e-02 31 3.271872e-03 6.645423e-04 3.969375e-02 -1.698660e-03 3.095902e-01 31 47 FALSE TRUE 103 TRUE 2.2568910 2.0368816 0.5480306 2.1990703 0.7752555 0.9855300 0.5199748 0.5385067 U 0.4686274 0.9018715 13773 129 183713 183714 1 259 Same - - 0.000000 0 0.000000 0.00000000 1.384289 3.073505 1.0442475 1350 Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) R tryptophan synthase beta subunit 1.633981 3.543571 1.0842639 410 ABC-type branched-chain amino acid transport systems, ATPase component E ABC transporter ATP-binding component 0.000000e+00 0 6.234577e-02 -1.225229e-02 -4.929163e-02 -5.078993e-01 2.164489e+00 47 0 FALSE TRUE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4046095 0.4064935 U 0.4686274 0.6162291 13773 129 183714 183715 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.633981 3.543571 1.0842639 410 ABC-type branched-chain amino acid transport systems, ATPase component E ABC transporter ATP-binding component 1.720677 3.754533 1.0415022 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid ABC transporter, ATP-binding protein, putative 0.000000e+00 0 7.516318e-03 4.916808e-02 6.951121e-01 8.967487e-01 3.492148e-03 E 0 14 FALSE TRUE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8041851 0.6477695 Y 1.4497162 0.7118045 13773 129 183715 183716 1 161 Same - - 2.079442 0 2.079442 2.07944154 1.720677 3.754533 1.0415022 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid ABC transporter, ATP-binding protein, putative 1.492286 3.332409 1.1391684 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ long-chain-fatty-acid--CoA ligase 2.480582e-03 3 5.216249e-02 1.101197e-02 -3.041085e-02 4.446254e-01 2.723510e-01 14 3 FALSE TRUE 100 TRUE 2.9335626 1.6614134 0.5480306 2.9479804 0.7136133 0.5047177 0.6530974 0.5529566 U 0.4686274 0.8396881 13773 129 183716 183717 1 97 Same - - 0.000000 0 0.000000 -0.13150953 1.492286 3.332409 1.1391684 318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II IQ long-chain-fatty-acid--CoA ligase 1.596366 3.533125 1.1433920 1804 Predicted acyl-CoA transferases/carnitine dehydratase C fatty acid co-A racemase, conjectural 1.841759e-02 3 1.083268e-02 5.928471e-03 1.391820e-01 3.922343e-01 1.654485e-01 3 17 FALSE TRUE 99 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.7136133 0.6663050 0.6308958 0.5885871 U 0.4686274 0.5537552 13773 129 183717 183718 1 -18 Same - - 0.000000 0 0.000000 -0.24889054 1.596366 3.533125 1.1433920 1804 Predicted acyl-CoA transferases/carnitine dehydratase C fatty acid co-A racemase, conjectural 1.407270 2.975353 1.0280827 824 Predicted thioesterase R conserved hypothetical protein -8.914191e-03 8 3.575732e-02 -6.396592e-03 -1.024829e-01 -2.883882e-01 1.431540e+00 17 8 FALSE TRUE 98 TRUE 0.4469764 0.2663985 0.5480306 0.4469764 0.7652913 0.5247582 0.4431184 0.4189018 U 0.4686274 0.5465600 13773 129 183718 183719 1 219 Divergent - + 0.000000 0 0.000000 0.00000000 1.407270 2.975353 1.0280827 824 Predicted thioesterase R conserved hypothetical protein 1.650018 3.583547 1.1112504 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 8.021092e-03 5 5.892646e-02 -8.763835e-03 1.351329e-02 -3.117571e-01 1.603537e+00 8 5 FALSE TRUE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7448207 0.5795898 0.4370387 0.4146495 U 0.4686274 0.6162291 13773 129 183719 183720 1 -3 Same + + 0.000000 0 0.000000 -0.08004271 1.650018 3.583547 1.1112504 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.620399 3.419666 0.9696495 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 3.777386e-02 1 8.772977e-04 3.356887e-02 3.855818e-01 8.358808e-01 1.192714e-03 5 1 TRUE TRUE 98 TRUE 0.4469764 0.2967290 0.5480306 0.4469764 0.6329203 0.7874252 0.7917785 0.6516158 U 0.4686274 0.5561190 13773 129 183720 183721 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.620399 3.419666 0.9696495 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.668464 3.545638 1.0853747 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 0.000000e+00 0 2.310297e-03 3.668642e-02 4.968113e-01 8.510286e-01 2.643996e-03 1 0 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7950987 0.6490066 U 0.4686274 0.6162291 13773 129 183721 183722 1 375 Divergent - + 0.000000 0 0.000000 0.00000000 1.668464 3.545638 1.0853747 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.419482 2.997837 1.0570901 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 0.000000e+00 0 6.199213e-02 -6.926884e-03 -1.773293e-01 -2.133031e-01 1.376975e+00 I 0 3 FALSE TRUE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4607302 0.4207387 Y 1.4497162 0.7118045 13773 129 183722 183723 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.419482 2.997837 1.0570901 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 1.376304 2.948863 1.0449166 2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs C molybdopterin binding oxidoreductase small and medium subunit 5.631536e-04 1 1.864336e-03 2.396120e-03 6.048634e-02 1.392683e-01 1.556100e-01 0 3 1 TRUE TRUE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.5271079 0.5912363 N 0.5492530 0.6245624 13773 129 183723 183724 1 -3 Same - - 2.662588 0 2.662588 2.66258783 1.376304 2.948863 1.0449166 2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs C molybdopterin binding oxidoreductase small and medium subunit 1.384304 3.019461 1.0766702 1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs C molybdopterin binding oxidoreductase large subunit 5.285113e-02 1 6.399081e-05 5.037626e-03 7.675074e-02 3.422293e-01 4.458099e-03 C 1 2 FALSE TRUE 98 TRUE 2.9244472 1.7076796 0.5480306 2.9399224 0.6329203 0.8555544 0.6095612 0.6467962 Y 1.4497162 0.8953487 13773 129 183724 183725 1 -3 Same - - 0.000000 0 0.000000 -0.12361396 1.384304 3.019461 1.0766702 1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs C molybdopterin binding oxidoreductase large subunit 1.455097 3.256751 1.0751396 1024 Enoyl-CoA hydratase/carnithine racemase I enoyl-CoA hydratase 7.877708e-02 2 5.011689e-03 -2.485087e-04 6.436695e-03 -7.336514e-02 4.696930e-01 0 2 5 FALSE TRUE 97 TRUE 0.4469764 0.2928786 0.5480306 0.4469764 0.6838149 0.9476794 0.5003455 0.4991754 N 0.5492530 0.5636296 13773 129 183725 183726 1 -72 Same - - 0.000000 0 0.000000 -0.76090838 1.455097 3.256751 1.0751396 1024 Enoyl-CoA hydratase/carnithine racemase I enoyl-CoA hydratase 1.413578 2.975708 1.0490274 1012 NAD-dependent aldehyde dehydrogenases C aldehyde dehydrogenase 1.712493e-02 5 1.723805e-03 -1.400711e-04 2.269644e-02 -3.668257e-02 1.673268e-01 0 5 58 FALSE TRUE 96 TRUE 0.4469764 0.2203228 0.5480306 0.4469764 0.7448207 0.6537337 0.5100249 0.5882371 N 0.5492530 0.5407745 13773 129 183726 183727 1 138 Divergent - + 0.000000 0 0.000000 -0.75608581 1.413578 2.975708 1.0490274 1012 NAD-dependent aldehyde dehydrogenases C aldehyde dehydrogenase 1.356058 2.932633 0.9861445 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.809586e-03 7 3.308587e-03 3.605047e-03 8.233850e-02 2.058889e-01 2.198840e-01 0 58 7 FALSE TRUE 95 FALSE 0.4469764 0.2207995 0.5480306 0.4469764 0.7596462 0.4911605 0.5516174 0.5744992 N 0.5492530 0.5409253 13773 129 183727 183728 1 137 Same + + 0.000000 0 0.000000 0.00000000 1.356058 2.932633 0.9861445 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.665645 3.450232 1.0550238 - - - hypothetical protein 0.000000e+00 0 9.584426e-02 -2.042572e-02 -1.245927e-01 -7.057413e-01 2.863706e+00 7 0 TRUE TRUE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3865283 0.4015264 U 0.4686274 0.6162291 13773 129 183728 183729 1 479 Same + + 0.000000 0 0.000000 0.00000000 1.665645 3.450232 1.0550238 - - - hypothetical protein 1.656183 3.659926 1.1397275 - - - hypothetical protein 0.000000e+00 0 8.953784e-05 4.387672e-02 5.236871e-01 8.874461e-01 9.954005e-05 0 0 TRUE TRUE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8027433 0.6550803 U 0.4686274 0.6162291 13773 129 183729 183730 1 11 Same + + 0.000000 0 0.000000 0.00000000 1.656183 3.659926 1.1397275 - - - hypothetical protein 1.507435 3.309591 1.0323923 - - - hypothetical protein 0.000000e+00 0 2.212597e-02 1.147682e-02 5.639943e-02 5.177968e-01 1.478382e-01 0 0 TRUE TRUE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6829633 0.5936859 U 0.4686274 0.6162291 13773 129 183730 183731 1 168 Same + + 0.000000 0 0.000000 0.00000000 1.507435 3.309591 1.0323923 - - - hypothetical protein 1.355364 2.889434 1.0417522 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 0.000000e+00 0 2.312538e-02 -5.381614e-03 -2.674351e-02 -4.138981e-01 1.694193e+00 0 4 TRUE TRUE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4167488 0.4122525 U 0.4686274 0.6162291 13773 129 183731 183732 1 -3 Same + + 7.133136 0 9.795724 9.79572415 1.355364 2.889434 1.0417522 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.373972 2.940550 1.0061524 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.586742e-01 4 3.462305e-04 7.434628e-03 9.946938e-02 4.765577e-01 1.272758e-02 I 4 6 TRUE TRUE 100 TRUE 2.7473022 1.8342605 0.5480306 2.7696028 0.7323301 1.0926286 0.6651784 0.6416331 Y 1.4497162 0.9113169 13773 129 183732 183733 1 -3 Same + + 7.133136 0 9.795724 9.79572415 1.373972 2.940550 1.0061524 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.277148 2.642724 0.9188220 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.586742e-01 4 9.374909e-03 1.349026e-02 2.403508e-01 6.191344e-01 1.135116e-01 6 4 TRUE TRUE 101 TRUE 2.7473022 1.8342605 0.5480306 2.7696028 0.7323301 1.0926286 0.7263909 0.6022559 U 0.4686274 0.8698043 13773 129 183733 183734 1 -3 Same + + 5.053695 0 5.053695 5.05369478 1.277148 2.642724 0.9188220 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.280044 2.666354 0.8613930 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 8.678342e-02 2 8.389362e-06 2.985672e-02 3.672887e-01 9.440120e-01 9.423910e-06 4 2 TRUE TRUE 102 TRUE 2.8165621 1.7676464 0.5480306 2.8829874 0.6838149 0.9642105 0.8099780 0.6557762 U 0.4686274 0.8588497 13773 129 183734 183735 1 -3 Same + + 2.856470 0 2.856470 2.85647021 1.280044 2.666354 0.8613930 1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon R conserved protein associated with acetyl-CoA C-acyltransferase 1.380022 2.913635 1.0094602 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 1.728481e-02 2 9.995512e-03 1.222938e-02 1.021019e-01 5.650671e-01 1.502083e-01 2 6 TRUE TRUE 103 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6838149 0.6558938 0.7051584 0.5931245 U 0.4686274 0.8518227 13773 129 183735 183736 1 387 Same + + 0.000000 0 0.000000 0.00000000 1.380022 2.913635 1.0094602 1960 Acyl-CoA dehydrogenases I acyl-CoA dehydrogenase 1.526711 3.254370 1.0135603 - - - paREP7 0.000000e+00 0 2.151787e-02 -5.375573e-03 -4.064460e-02 -3.840132e-01 1.541943e+00 6 0 TRUE TRUE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4218475 0.4157486 U 0.4686274 0.6162291 13773 129 183736 183737 1 408 Convergent + - 0.000000 0 0.000000 0.00000000 1.526711 3.254370 1.0135603 - - - paREP7 1.581087 3.609700 1.1630527 - - - hypothetical protein 0.000000e+00 0 2.956707e-03 9.768357e-03 1.632617e-01 5.464219e-01 2.876708e-02 0 0 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6969337 0.6337043 U 0.4686274 0.6162291 13773 129 183737 183738 1 780 Divergent - + 0.000000 0 0.000000 0.00000000 1.581087 3.609700 1.1630527 - - - hypothetical protein 1.455402 3.115528 1.0506060 - - - hypothetical protein 0.000000e+00 0 1.579668e-02 5.199736e-04 -1.585775e-02 1.106838e-01 4.834678e-01 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5200033 0.4957719 U 0.4686274 0.6162291 13773 129 183738 183739 1 43 Same + + 0.000000 0 0.000000 0.00000000 1.455402 3.115528 1.0506060 - - - hypothetical protein 1.483992 3.330573 1.1092369 135 Phosphoribosylanthranilate isomerase E phosphoribosyl anthranilate isomerase 0.000000e+00 0 8.173616e-04 1.306960e-04 2.492369e-02 5.339470e-02 7.092023e-02 0 42 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187710 0.6175203 U 0.4686274 0.6162291 13773 129 183739 183740 1 382 Same + + 0.000000 0 0.000000 0.00000000 1.483992 3.330573 1.1092369 135 Phosphoribosylanthranilate isomerase E phosphoribosyl anthranilate isomerase 2.047544 4.271052 1.1346517 - - - paREP13 0.000000e+00 0 3.175918e-01 1.943381e-02 1.147798e+00 3.995396e-01 3.592636e-01 42 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6348076 0.5214465 U 0.4686274 0.6162291 13773 129 183740 183741 1 -194 Convergent + - 0.000000 0 0.000000 0.00000000 2.047544 4.271052 1.1346517 - - - paREP13 1.444028 3.411617 1.0857366 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, frameshift 0.000000e+00 0 3.642322e-01 -4.390606e-03 -9.329940e-01 2.607360e-02 9.469993e-01 0 0 TRUE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173851 0.4429071 U 0.4686274 0.6162291 13773 129 183741 183742 1 146 Same - - 0.000000 0 0.000000 0.00000000 1.444028 3.411617 1.0857366 1373 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, frameshift 1.426072 3.186326 1.1059304 - - - conserved within P. aerophilum 0.000000e+00 0 3.224000e-04 1.864827e-04 2.440849e-02 -4.245472e-03 3.564359e-02 0 0 FALSE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197926 0.6297015 U 0.4686274 0.6162291 13773 129 183742 183743 1 57 Same - - 0.000000 0 0.000000 0.00000000 1.426072 3.186326 1.1059304 - - - conserved within P. aerophilum 1.533153 3.188659 1.0302539 - - - hypothetical protein 0.000000e+00 0 1.146632e-02 -2.070209e-03 1.188013e-02 -1.122553e-01 7.270082e-01 0 0 FALSE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4876857 0.4621159 U 0.4686274 0.6162291 13773 129 183743 183744 1 50 Divergent - + 0.000000 0 0.000000 0.00000000 1.533153 3.188659 1.0302539 - - - hypothetical protein 1.470267 3.285697 1.0997870 2445 Uncharacterized conserved protein S paREP11 0.000000e+00 0 3.954655e-03 1.543183e-03 2.270966e-02 1.885041e-01 1.736644e-01 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5457001 0.5866463 U 0.4686274 0.6162291 13773 129 183744 183745 1 -12 Convergent + - 0.000000 0 0.000000 0.00000000 1.470267 3.285697 1.0997870 2445 Uncharacterized conserved protein S paREP11 1.296562 2.775444 0.9720906 1533 DNA repair photolyase L conserved hypothetical protein 0.000000e+00 0 3.017344e-02 -2.922341e-03 4.654259e-02 -2.600057e-01 1.500296e+00 0 4 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4505180 0.4170968 U 0.4686274 0.6162291 13773 129 183745 183746 1 187 Divergent - + 0.000000 0 0.000000 0.00000000 1.296562 2.775444 0.9720906 1533 DNA repair photolyase L conserved hypothetical protein 1.785687 3.482784 1.0691554 - - - paREP7 0.000000e+00 0 2.392432e-01 -5.175898e-02 -3.615243e-01 -9.406947e-01 3.764136e+00 4 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3779345 0.3989958 U 0.4686274 0.6162291 13773 129 183746 183747 1 372 Convergent + - 0.000000 0 0.000000 0.00000000 1.785687 3.482784 1.0691554 - - - paREP7 1.489346 3.259215 1.0929864 - - - conserved hypothetical protein 0.000000e+00 0 8.781829e-02 1.268740e-02 -1.110567e-01 4.346920e-01 3.011087e-01 0 0 TRUE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6495201 0.5411666 U 0.4686274 0.6162291 13773 129 183747 183748 1 108 Divergent - + 0.000000 0 0.000000 0.00000000 1.489346 3.259215 1.0929864 - - - conserved hypothetical protein 1.435255 3.349167 1.0917653 4243 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 2.925797e-03 -6.124764e-04 1.057987e-02 -2.632452e-02 2.496164e-01 0 0 FALSE TRUE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5132638 0.5628925 U 0.4686274 0.6162291 13773 129 183748 183749 1 66 Same + + 0.000000 0 0.000000 0.00000000 1.435255 3.349167 1.0917653 4243 Predicted membrane protein S conserved hypothetical protein 1.497971 3.524689 1.1746551 - - - conserved within P. aerophilum 0.000000e+00 0 3.933312e-03 -7.516732e-04 1.679710e-02 -2.958637e-02 3.070334e-01 0 0 TRUE TRUE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5122699 0.5396610 U 0.4686274 0.6162291 13773 129 183749 183750 1 47 Convergent + - 0.000000 0 0.000000 0.00000000 1.497971 3.524689 1.1746551 - - - conserved within P. aerophilum 1.393321 2.941650 1.0400189 4992 Ornithine/acetylornithine aminotransferase E acetylornithine aminotransferase (argD) 0.000000e+00 0 1.095160e-02 -2.704875e-03 -7.834006e-03 -2.325185e-01 9.306400e-01 0 37 TRUE TRUE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4561508 0.4448241 U 0.4686274 0.6162291 13773 129 183750 183751 1 30 Divergent - + 0.000000 0 0.000000 0.00000000 1.393321 2.941650 1.0400189 4992 Ornithine/acetylornithine aminotransferase E acetylornithine aminotransferase (argD) 1.683119 3.958646 1.1256252 - - - hypothetical protein 0.000000e+00 0 8.398299e-02 -1.345674e-02 -8.801744e-03 -4.524001e-01 2.050853e+00 37 0 FALSE TRUE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4113045 0.4076071 U 0.4686274 0.6162291 13773 129 183751 183752 1 50 Same + + 0.000000 0 0.000000 0.00000000 1.683119 3.958646 1.1256252 - - - hypothetical protein 1.309833 2.744578 0.9996689 1531 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 1.393428e-01 -3.280320e-02 -4.482813e-01 -8.878260e-01 3.552777e+00 0 0 TRUE TRUE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3798546 0.3995439 U 0.4686274 0.6162291 13773 129 183752 183753 1 66 Same + + 0.000000 0 0.000000 0.00000000 1.309833 2.744578 0.9996689 1531 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.403393 3.115893 1.0785792 62 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 8.753522e-03 6.794834e-03 5.514597e-02 3.535716e-01 2.919151e-01 0 42 TRUE TRUE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6139438 0.5460473 U 0.4686274 0.6162291 13773 129 183753 183754 1 18 Convergent + - 0.000000 0 0.000000 0.00000000 1.403393 3.115893 1.0785792 62 Uncharacterized conserved protein S conserved hypothetical protein 1.448060 3.069529 1.0008530 - - - paREP8 0.000000e+00 0 1.995137e-03 1.599704e-04 1.678536e-02 -2.468829e-02 2.001927e-01 42 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5139316 0.5800294 U 0.4686274 0.6162291 13773 129 183754 183755 1 62 Divergent - + 0.000000 0 0.000000 0.00000000 1.448060 3.069529 1.0008530 - - - paREP8 1.542144 3.417951 1.0551868 - - - hypothetical protein 0.000000e+00 0 8.851715e-03 -3.024487e-04 3.808783e-02 4.655647e-02 4.325864e-01 0 0 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186386 0.5070154 U 0.4686274 0.6162291 13773 129 183755 183756 1 7 Convergent + - 0.000000 0 0.000000 0.00000000 1.542144 3.417951 1.0551868 - - - hypothetical protein 1.554297 3.392551 1.1192120 675 Transposase and inactivated derivatives L paREP12 0.000000e+00 0 1.477029e-04 9.338633e-03 1.359045e-01 5.475928e-01 1.301089e-03 0 0 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6980958 0.6513850 U 0.4686274 0.6162291 13773 129 183756 183757 1 560 Divergent - + 0.000000 0 0.000000 0.00000000 1.554297 3.392551 1.1192120 675 Transposase and inactivated derivatives L paREP12 1.447747 3.257610 1.0962097 - - - hypothetical protein 0.000000e+00 0 1.135291e-02 -3.751770e-04 -1.050675e-02 4.597219e-02 4.866749e-01 0 0 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186259 0.4946318 U 0.4686274 0.6162291 13773 129 183757 183758 1 215 Convergent + - 0.000000 0 0.000000 0.00000000 1.447747 3.257610 1.0962097 - - - hypothetical protein 1.449362 3.469730 1.1312199 3374 Predicted membrane protein S conserved hypothetical protein 0.000000e+00 0 2.607647e-06 7.405050e-06 2.080099e-02 4.559995e-03 2.126270e-04 0 2 TRUE TRUE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195797 0.6544230 U 0.4686274 0.6162291 13773 129 183758 183759 1 197 Divergent - + 0.000000 0 0.000000 0.00000000 1.449362 3.469730 1.1312199 3374 Predicted membrane protein S conserved hypothetical protein 1.494680 3.583421 1.1916444 4732 Predicted membrane protein S conserved hypothetical protein 7.508473e-04 2 2.053709e-03 -8.791843e-05 2.445764e-02 3.549869e-02 1.574317e-01 2 2 FALSE TRUE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4618072 0.5176263 0.5905561 U 0.4686274 0.6162291 13773 129 183759 183760 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.494680 3.583421 1.1916444 4732 Predicted membrane protein S conserved hypothetical protein 1.478569 3.344013 1.1022495 - - - conserved hypothetical protein 3.728161e-04 1 2.595468e-04 1.176377e-03 3.160938e-02 1.673510e-01 1.378777e-02 2 1 TRUE TRUE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.5377629 0.6411621 U 0.4686274 0.6162291 13773 129 183760 183761 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.478569 3.344013 1.1022495 - - - conserved hypothetical protein 1.430975 3.145717 1.0825221 1122 ABC-type cobalt transport system, ATPase component P ribose ABC transporter, ATP-binding protein, putative 3.728161e-04 1 2.265243e-03 -5.548929e-04 1.343290e-02 -3.700770e-02 2.106268e-01 1 2 TRUE TRUE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.5097593 0.5759811 U 0.4686274 0.6162291 13773 129 183761 183762 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.430975 3.145717 1.0825221 1122 ABC-type cobalt transport system, ATPase component P ribose ABC transporter, ATP-binding protein, putative 1.380133 3.531618 1.1744893 - - - hypothetical protein 0.000000e+00 0 2.584820e-03 1.454991e-03 4.958648e-02 6.071826e-02 2.278725e-01 2 0 TRUE TRUE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184940 0.5715668 U 0.4686274 0.6162291 13773 129 183762 183763 1 78 Same + + 0.000000 0 0.000000 0.00000000 1.380133 3.531618 1.1744893 - - - hypothetical protein 1.403056 3.016718 1.0610696 1992 Uncharacterized conserved protein S phosphomethylpyrimidine kinase 0.000000e+00 0 5.254431e-04 3.444451e-03 5.404924e-02 2.236753e-01 3.890249e-02 0 10 TRUE TRUE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5585739 0.6284750 U 0.4686274 0.6162291 13773 129 183763 183764 1 26 Convergent + - 0.000000 0 0.000000 -0.40570826 1.403056 3.016718 1.0610696 1992 Uncharacterized conserved protein S phosphomethylpyrimidine kinase 1.438818 3.079294 1.0498586 212 5-formyltetrahydrofolate cyclo-ligase H conserved hypothetical protein 1.181248e-01 6 1.278954e-03 6.078040e-04 2.231241e-02 1.091819e-02 1.268081e-01 10 6 TRUE TRUE 112 FALSE 0.4469764 0.2413468 0.5480306 0.4469764 0.7537284 1.0524713 0.5188131 0.5988589 U 0.4686274 0.5386384 13773 129 183764 183765 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.438818 3.079294 1.0498586 212 5-formyltetrahydrofolate cyclo-ligase H conserved hypothetical protein 1.401938 3.307530 1.1509646 1030 Membrane-bound serine protease (ClpP class) O conserved hypothetical protein 0.000000e+00 0 1.360142e-03 6.218574e-04 3.381807e-02 1.131046e-02 1.368375e-01 0 6 0 FALSE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187697 0.5965788 N 0.5492530 0.6245624 13773 129 183765 183766 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.401938 3.307530 1.1509646 1030 Membrane-bound serine protease (ClpP class) O conserved hypothetical protein 1.499295 3.362662 1.1385525 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 0.000000e+00 0 9.478243e-03 -2.368958e-03 -7.344698e-03 -2.008371e-01 8.145651e-01 0 3 TRUE TRUE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4643861 0.4536353 U 0.4686274 0.6162291 13773 129 183766 183767 1 271 Divergent - + 0.000000 0 0.000000 0.00000000 1.499295 3.362662 1.1385525 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein 1.461588 3.376532 1.1301500 - - - hypothetical protein 0.000000e+00 0 1.421763e-03 4.883857e-04 2.088489e-02 9.945112e-02 9.423910e-02 3 0 FALSE TRUE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186154 0.6091015 U 0.4686274 0.6162291 13773 129 183767 183768 1 -64 Same + + 0.000000 0 0.000000 0.00000000 1.461588 3.376532 1.1301500 - - - hypothetical protein 1.402521 3.163052 1.1240829 4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats R conserved hypothetical protein 0.000000e+00 0 3.488973e-03 -4.982769e-04 2.071326e-02 -7.750224e-02 3.483083e-01 0 2 TRUE TRUE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4988628 0.5251543 U 0.4686274 0.6162291 13773 129 183768 183769 1 257 Same + + 0.000000 0 0.000000 0.00000000 1.402521 3.163052 1.1240829 4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats R conserved hypothetical protein 1.472702 3.227297 1.0643772 1708 Predicted nucleotidyltransferases R paREP11 0.000000e+00 0 4.925448e-03 -1.041440e-03 3.648521e-03 -1.142932e-01 4.675915e-01 2 0 TRUE TRUE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4868677 0.4996268 U 0.4686274 0.6162291 13773 129 183769 183770 1 33 Convergent + - 0.000000 0 0.000000 0.00000000 1.472702 3.227297 1.0643772 1708 Predicted nucleotidyltransferases R paREP11 1.515578 3.332004 1.1763955 - - - hypothetical protein 0.000000e+00 0 1.838357e-03 1.367768e-03 4.603909e-02 1.736721e-01 9.376850e-02 0 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5394670 0.6094409 U 0.4686274 0.6162291 13773 129 183770 183771 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.515578 3.332004 1.1763955 - - - hypothetical protein 1.460108 4.043885 1.2814136 - - - hypothetical protein 0.000000e+00 0 3.076924e-03 5.594169e-04 1.700920e-02 1.090606e-01 1.717508e-01 0 0 FALSE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197664 0.5873404 U 0.4686274 0.6162291 13773 129 183771 183772 1 20 Convergent + - 0.000000 0 0.000000 0.00000000 1.460108 4.043885 1.2814136 - - - hypothetical protein 1.395764 3.073792 1.0597806 - - - hypothetical protein 0.000000e+00 0 4.140255e-03 -4.848424e-04 2.273466e-02 -8.410840e-02 4.136178e-01 0 0 TRUE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4970159 0.5101580 U 0.4686274 0.6162291 13773 129 183772 183773 1 72 Divergent - + 0.000000 0 0.000000 0.00000000 1.395764 3.073792 1.0597806 - - - hypothetical protein 1.541634 3.367028 1.0812058 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 2.127826e-02 -5.020062e-03 -2.513651e-02 -3.321928e-01 1.396859e+00 0 1 FALSE TRUE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4316239 0.4197398 U 0.4686274 0.6162291 13773 129 183773 183774 1 -10 Same + + 2.662588 0 2.662588 2.66258783 1.541634 3.367028 1.0812058 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.426140 3.081344 1.0662925 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 7.158483e-02 1 1.333890e-02 -2.278839e-03 -2.496826e-02 -1.162675e-01 7.789451e-01 1 1 TRUE TRUE 114 TRUE 2.9244472 1.7076796 0.5480306 2.9399224 0.6329203 0.9205230 0.4862809 0.4575852 U 0.4686274 0.8476113 13773 129 183774 183775 1 485 Same + + 0.000000 0 0.000000 0.00000000 1.426140 3.081344 1.0662925 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.495735 3.522656 1.1760911 730 Predicted permeases R conserved hypothetical protein 9.520652e-04 1 4.843488e-03 -1.119767e-03 1.101895e-02 -7.705814e-02 4.086967e-01 1 5 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.4991300 0.5107204 U 0.4686274 0.6162291 13773 129 183775 183776 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.495735 3.522656 1.1760911 730 Predicted permeases R conserved hypothetical protein 1.508732 3.650826 1.1573022 - - - hypothetical protein 0.000000e+00 0 1.689025e-04 2.542543e-03 5.382171e-02 2.675018e-01 6.617941e-03 5 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5767111 0.6448898 U 0.4686274 0.6162291 13773 129 183776 183777 1 532 Same + + 0.000000 0 0.000000 0.00000000 1.508732 3.650826 1.1573022 - - - hypothetical protein 1.387368 2.959396 1.0353109 174 Glutamine synthetase E glutamine synthetase 0.000000e+00 0 1.472924e-02 -3.671133e-03 -2.012538e-02 -2.941232e-01 1.177633e+00 0 23 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4420385 0.4293379 U 0.4686274 0.6162291 13773 129 183777 183778 1 298 Same + + 0.000000 0 0.000000 -0.15206951 1.387368 2.959396 1.0353109 174 Glutamine synthetase E glutamine synthetase 1.366014 2.861802 0.9996254 17 Aspartyl/asparaginyl-tRNA synthetases J asparaginyl-tRNA synthetase 1.599790e-02 1 4.559767e-04 5.466417e-03 9.275442e-02 3.619047e-01 2.647176e-02 0 23 1 TRUE TRUE 118 TRUE 0.4469764 0.2765129 0.5480306 0.4469764 0.6329203 0.6457313 0.6161683 0.6347546 N 0.5492530 0.5584944 13773 129 183778 183779 1 104 Convergent + - 0.000000 0 0.000000 0.00000000 1.366014 2.861802 0.9996254 17 Aspartyl/asparaginyl-tRNA synthetases J asparaginyl-tRNA synthetase 1.449540 3.559671 1.2209676 477 Permeases of the major facilitator superfamily GEPR tetracycline resistance protein 4.041771e-03 1 6.976549e-03 1.582254e-04 4.084509e-03 -5.388945e-02 5.878170e-01 1 19 TRUE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5366044 0.5055660 0.4784697 U 0.4686274 0.6162291 13773 129 183779 183780 1 42 Same - - 0.000000 0 0.000000 0.00000000 1.449540 3.559671 1.2209676 477 Permeases of the major facilitator superfamily GEPR tetracycline resistance protein 1.452109 3.193011 1.0786093 - - - hypothetical protein 0.000000e+00 0 6.601290e-06 -1.327057e-06 2.071475e-02 8.110453e-03 6.414149e-04 19 0 FALSE TRUE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190898 0.6527891 U 0.4686274 0.6162291 13773 129 183780 183781 1 130 Divergent - + 0.000000 0 0.000000 0.00000000 1.452109 3.193011 1.0786093 - - - hypothetical protein 1.348715 2.725685 1.0158992 1146 Ferredoxin C adenylylsulfate reductase beta subunit part 1, authentic frameshift 0.000000e+00 0 1.069027e-02 -7.352588e-05 4.664999e-02 -8.158161e-02 7.939179e-01 0 2 FALSE TRUE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4974887 0.4559908 U 0.4686274 0.6162291 13773 129 183781 183782 1 3 Same + + 0.000000 0 0.000000 0.00000000 1.348715 2.725685 1.0158992 1146 Ferredoxin C adenylylsulfate reductase beta subunit part 1, authentic frameshift 1.332370 2.947806 1.0110938 1146 Ferredoxin C adenylylsulfate reductase beta subunit part 2, authentic frameshift 0.000000e+00 0 2.671711e-04 1.222101e-02 1.728317e-01 6.798468e-01 5.772734e-03 C 2 0 TRUE TRUE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7456945 0.6458271 Y 1.4497162 0.7118045 13773 129 183782 183783 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.332370 2.947806 1.0110938 1146 Ferredoxin C adenylylsulfate reductase beta subunit part 2, authentic frameshift 1.319150 2.857916 1.0119104 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C adenylylsulfate reductase alpha subunit part 1, authentic frameshift 0.000000e+00 0 1.747689e-04 1.573997e-02 2.132094e-01 7.779144e-01 1.414176e-03 C 0 1 TRUE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7767975 0.6511912 Y 1.4497162 0.7118045 13773 129 183783 183784 1 7 Same + + 0.000000 0 0.000000 0.00000000 1.319150 2.857916 1.0119104 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C adenylylsulfate reductase alpha subunit part 1, authentic frameshift 1.312458 2.770860 0.9407806 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C adenylylsulfate reductase alpha subunit part 2, authentic frameshift 0.000000e+00 0 4.477548e-05 1.837312e-02 2.401695e-01 8.249350e-01 2.126270e-04 C 1 0 TRUE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7898880 0.6544230 Y 1.4497162 0.7118045 13773 129 183784 183785 1 96 Same + + 0.000000 0 0.000000 0.00000000 1.312458 2.770860 0.9407806 1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit C adenylylsulfate reductase alpha subunit part 2, authentic frameshift 1.410624 2.935173 1.0236374 622 Predicted phosphoesterase R conserved hypothetical protein 0.000000e+00 0 9.636503e-03 5.664192e-03 4.216630e-02 2.831761e-01 3.675914e-01 0 14 TRUE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5859515 0.5196393 U 0.4686274 0.6162291 13773 129 183785 183786 1 9 Convergent + - 0.000000 0 0.000000 0.00000000 1.410624 2.935173 1.0236374 622 Predicted phosphoesterase R conserved hypothetical protein 1.328405 2.712864 0.9203653 2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit P siroheme-sulfite reductase gamma subunit homolog 6.432019e-04 4 6.760045e-03 5.014084e-03 1.135558e-01 2.696464e-01 3.164602e-01 14 4 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.4592152 0.5794887 0.5367838 U 0.4686274 0.6162291 13773 129 183786 183787 1 131 Divergent - + 0.000000 0 0.000000 0.00000000 1.328405 2.712864 0.9203653 2920 Dissimilatory sulfite reductase (desulfoviridin), gamma subunit P siroheme-sulfite reductase gamma subunit homolog 1.375551 3.017219 1.0285430 2044 Predicted peroxiredoxins R conserved hypothetical protein 3.090486e-03 4 2.222782e-03 9.327666e-03 1.059937e-01 5.459837e-01 6.031303e-02 4 4 FALSE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.5166149 0.6961613 0.6204913 U 0.4686274 0.6162291 13773 129 183787 183788 1 1 Convergent + - 0.000000 0 0.000000 0.00000000 1.375551 3.017219 1.0285430 2044 Predicted peroxiredoxins R conserved hypothetical protein 1.372874 2.931209 1.0226173 - - - glutathione-S-transferase homolog 0.000000e+00 0 7.167937e-06 5.955046e-03 9.141526e-02 4.008366e-01 1.908342e-04 4 0 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6360246 0.6545960 U 0.4686274 0.6162291 13773 129 183788 183789 1 207 Same - - 0.000000 0 0.000000 0.00000000 1.372874 2.931209 1.0226173 - - - glutathione-S-transferase homolog 1.424391 3.095209 1.0821613 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase beta subunit 0.000000e+00 0 2.654017e-03 2.120180e-03 3.172226e-02 1.144546e-01 2.127454e-01 0 3 FALSE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5209588 0.5756211 U 0.4686274 0.6162291 13773 129 183789 183790 1 -3 Same - - 0.000000 0 0.000000 -0.06453852 1.424391 3.095209 1.0821613 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase beta subunit 1.407052 2.975161 1.0253400 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase alpha subunit 4.578021e-02 1 3.006382e-04 1.197297e-03 3.787823e-02 6.052094e-02 2.548225e-02 C 3 1 FALSE TRUE 120 TRUE 0.4469764 0.3032773 0.5480306 0.4469764 0.6329203 0.8313457 0.5185395 0.6352777 Y 1.4497162 0.6602392 13773 129 183790 183791 1 143 Same - - 0.000000 0 0.000000 0.00000000 1.407052 2.975161 1.0253400 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase alpha subunit 1.388665 2.945437 1.0170421 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 0.000000e+00 0 3.380939e-04 2.781434e-03 5.825857e-02 1.727314e-01 2.955338e-02 0 1 0 FALSE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5388957 0.6332836 N 0.5492530 0.6245624 13773 129 183791 183792 1 105 Same - - 0.000000 0 0.000000 0.00000000 1.388665 2.945437 1.0170421 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 1.726880 3.748294 1.0150510 - - - hypothetical protein 0.000000e+00 0 1.143894e-01 -1.728081e-02 1.423773e-03 -5.001770e-01 2.221312e+00 0 0 FALSE TRUE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4052864 0.4055375 U 0.4686274 0.6162291 13773 129 183792 183793 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.726880 3.748294 1.0150510 - - - hypothetical protein 1.590293 3.327726 1.0147741 175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related e EH phosphoadenosine phosphosulfate reductase (PAPS reductase) 0.000000e+00 0 1.865588e-02 3.826515e-02 3.244092e-01 8.318733e-01 1.722279e-02 0 28 FALSE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7908326 0.6392215 U 0.4686274 0.6162291 13773 129 183793 183794 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.590293 3.327726 1.0147741 175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related e EH phosphoadenosine phosphosulfate reductase (PAPS reductase) 1.630585 3.634120 1.0483722 - - - hypothetical protein 0.000000e+00 0 1.623468e-03 2.488987e-02 3.443051e-01 7.751991e-01 4.155945e-03 28 0 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7754102 0.6472310 U 0.4686274 0.6162291 13773 129 183794 183795 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.630585 3.634120 1.0483722 - - - hypothetical protein 1.664315 3.592628 1.0868482 155 Sulfite reductase, beta subunit (hemoprotein) P ferredoxin-nitrite reductase 0.000000e+00 0 1.137677e-03 3.815401e-02 5.004321e-01 8.628120e-01 9.900996e-04 0 33 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7970027 0.6518633 U 0.4686274 0.6162291 13773 129 183795 183796 1 110 Divergent - + 2.856470 0 2.856470 2.76945883 1.664315 3.592628 1.0868482 155 Sulfite reductase, beta subunit (hemoprotein) P ferredoxin-nitrite reductase 1.640701 3.990078 1.1174448 730 Predicted permeases R conserved hypothetical protein 2.229338e-02 2 5.575930e-04 4.030794e-02 4.679090e-01 8.700625e-01 5.660236e-04 33 2 FALSE TRUE 114 FALSE 2.8950318 1.7153274 0.5480306 2.9213001 0.6838149 0.6943202 0.7993894 0.6530578 U 0.4686274 0.8493330 13773 129 183796 183797 1 97 Same + + 0.000000 0 0.000000 0.00000000 1.640701 3.990078 1.1174448 730 Predicted permeases R conserved hypothetical protein 1.725507 3.732178 1.0402171 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 3.728161e-04 1 7.192024e-03 5.189218e-02 7.272807e-01 9.018682e-01 3.402032e-03 2 1 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.8056295 0.6479144 U 0.4686274 0.6162291 13773 129 183797 183798 1 -9 Same + + 0.000000 0 0.000000 0.00000000 1.725507 3.732178 1.0402171 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 1.685775 3.453720 1.0463321 2897 Rhodanese-related sulfurtransferase P thiosulfate sulfurtransferase 0.000000e+00 0 1.578681e-03 6.424738e-02 7.206282e-01 9.424523e-01 2.850733e-04 0 1 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8094937 0.6540676 N 0.5492530 0.6245624 13773 129 183798 183799 1 187 Same + + 0.000000 0 0.000000 0.00000000 1.685775 3.453720 1.0463321 2897 Rhodanese-related sulfurtransferase P thiosulfate sulfurtransferase 1.336930 2.932055 1.0411641 - - - paREP1 0.000000e+00 0 1.216923e-01 -2.682792e-02 -3.991775e-01 -8.154133e-01 3.274905e+00 0 0 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3820080 0.4002278 U 0.4686274 0.6162291 13773 129 183799 183800 1 191 Convergent + - 0.000000 0 0.000000 0.00000000 1.336930 2.932055 1.0411641 - - - paREP1 1.361973 2.994409 1.0502327 1797 Cobyrinic acid a,c-diamide synthase H cobyrinic acid a,c-diamide synthase (cbiA) part 2, authentic frameshift 0.000000e+00 0 6.271531e-04 1.023518e-02 1.274440e-01 6.040821e-01 1.803795e-02 0 20 TRUE TRUE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7213853 0.6386975 U 0.4686274 0.6162291 13773 129 183800 183801 1 84 Same - - 0.000000 0 0.000000 0.00000000 1.361973 2.994409 1.0502327 1797 Cobyrinic acid a,c-diamide synthase H cobyrinic acid a,c-diamide synthase (cbiA) part 2, authentic frameshift 1.450176 3.503389 1.1989552 - - - cobyrinic acid a,c-diamide synthase (cbiA) part 1, authentic frameshift 0.000000e+00 0 7.779717e-03 1.088055e-04 1.708108e-03 -6.073651e-02 6.370563e-01 20 0 FALSE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5036415 0.4715010 U 0.4686274 0.6162291 13773 129 183801 183802 1 50 Same - - 0.000000 0 0.000000 0.00000000 1.450176 3.503389 1.1989552 - - - cobyrinic acid a,c-diamide synthase (cbiA) part 1, authentic frameshift 1.348888 2.971342 1.0362232 - - - conserved hypothetical protein 0.000000e+00 0 1.025927e-02 1.247277e-04 4.887551e-02 -6.681670e-02 7.560856e-01 0 1 FALSE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5018373 0.4589254 U 0.4686274 0.6162291 13773 129 183802 183803 1 77 Same - - 0.000000 0 0.000000 0.00000000 1.348888 2.971342 1.0362232 - - - conserved hypothetical protein 1.475735 3.213049 1.0244982 - - - hypothetical protein 0.000000e+00 0 1.609028e-02 -2.495237e-03 -3.361573e-02 -2.570336e-01 1.236653e+00 1 0 FALSE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4511785 0.4267515 U 0.4686274 0.6162291 13773 129 183803 183804 1 42 Divergent - + 0.000000 0 0.000000 0.00000000 1.475735 3.213049 1.0244982 - - - hypothetical protein 1.448814 3.231571 1.1007316 1587 Uroporphyrinogen-III synthase H uroporphyrinogen-III synthase (hemD), conjectural 0.000000e+00 0 7.247710e-04 -6.277824e-05 1.851574e-02 2.313806e-02 6.609990e-02 0 0 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174534 0.6187763 U 0.4686274 0.6162291 13773 129 183804 183805 1 -56 Convergent + - 0.000000 0 0.000000 0.00000000 1.448814 3.231571 1.1007316 1587 Uroporphyrinogen-III synthase H uroporphyrinogen-III synthase (hemD), conjectural 1.303702 2.910906 0.9963818 1587 Uroporphyrinogen-III synthase H uroporphyrinogen-III synthase (hemD), conjectural 0.000000e+00 0 2.105745e-02 3.808861e-04 8.056744e-02 -6.610873e-02 1.013862e+00 H 0 5 TRUE TRUE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5020788 0.4384021 Y 1.4497162 0.7118045 13773 129 183805 183806 1 60 Divergent - + 0.000000 0 0.000000 0.00000000 1.303702 2.910906 0.9963818 1587 Uroporphyrinogen-III synthase H uroporphyrinogen-III synthase (hemD), conjectural 1.383255 2.893819 1.0218698 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase alpha subunit 1.917743e-03 2 6.328706e-03 1.006330e-02 9.479767e-02 5.231213e-01 1.425743e-01 0 5 2 FALSE TRUE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4923490 0.6855540 0.5949759 N 0.5492530 0.6245624 13773 129 183806 183807 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.383255 2.893819 1.0218698 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase alpha subunit 1.377029 2.967117 1.0294300 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase beta subunit 3.728161e-04 1 3.875986e-05 5.066944e-03 8.223480e-02 3.413152e-01 2.723510e-03 C 2 1 TRUE TRUE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.6087492 0.6489041 Y 1.4497162 0.7118045 13773 129 183807 183808 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.377029 2.967117 1.0294300 2221 Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits C sulfite reductase beta subunit 1.511308 3.318708 1.0549514 - - - hypothetical protein 0.000000e+00 0 1.803074e-02 -4.455498e-03 -3.628408e-02 -3.483478e-01 1.395046e+00 1 0 TRUE TRUE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4282296 0.4198811 U 0.4686274 0.6162291 13773 129 183808 183809 1 140 Same + + 0.000000 0 0.000000 0.00000000 1.511308 3.318708 1.0549514 - - - hypothetical protein 1.377458 3.166645 1.0819179 - - - hypothetical protein 0.000000e+00 0 1.791582e-02 -4.429818e-03 -2.629155e-02 -3.452844e-01 1.382384e+00 0 0 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4288342 0.4206426 U 0.4686274 0.6162291 13773 129 183809 183810 1 -22 Convergent + - 0.000000 0 0.000000 0.00000000 1.377458 3.166645 1.0819179 - - - hypothetical protein 1.418660 3.065875 1.0343557 - - - hypothetical protein 0.000000e+00 0 1.697609e-03 2.420085e-03 3.787307e-02 1.398797e-01 1.402655e-01 0 0 TRUE TRUE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5275007 0.5956690 U 0.4686274 0.6162291 13773 129 183810 183811 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.418660 3.065875 1.0343557 - - - hypothetical protein 1.557715 3.393217 1.1056643 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 0.000000e+00 0 1.933627e-02 -3.480215e-03 6.032795e-03 -1.774646e-01 9.984657e-01 0 21 FALSE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4714416 0.4393668 U 0.4686274 0.6162291 13773 129 183811 183812 1 125 Divergent - + 0.000000 0 0.000000 0.00000000 1.557715 3.393217 1.1056643 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 1.560840 3.375615 1.1221703 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 4.547022e-03 1 9.767960e-06 1.163671e-02 1.585099e-01 6.007855e-01 1.908342e-04 O 21 1 FALSE TRUE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5418901 0.7201436 0.6545960 Y 1.4497162 0.7118045 13773 129 183812 183813 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.560840 3.375615 1.1221703 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 1.360011 2.945558 1.0501620 709 Selenophosphate synthase E conserved protein with C terminal acylphosphatase domain 3.728161e-04 1 4.033228e-02 -1.000147e-02 -1.054162e-01 -5.647744e-01 2.262681e+00 0 1 2 TRUE TRUE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.3975280 0.4053266 N 0.5492530 0.6245624 13773 129 183813 183814 1 -3 Same + + 2.856470 0 2.856470 2.85647021 1.360011 2.945558 1.0501620 709 Selenophosphate synthase E conserved protein with C terminal acylphosphatase domain 1.449517 3.076755 1.0360340 2210 Uncharacterized conserved protein S conserved hypothetical protein 5.285113e-02 1 8.011183e-03 1.714479e-04 1.544926e-03 -5.542437e-02 6.382820e-01 2 1 TRUE TRUE 118 TRUE 2.8950318 1.7307027 0.5480306 2.9213001 0.6329203 0.8555544 0.5051313 0.4713615 U 0.4686274 0.8518227 13773 129 183814 183815 1 73 Convergent + - 0.000000 0 0.000000 0.00000000 1.449517 3.076755 1.0360340 2210 Uncharacterized conserved protein S conserved hypothetical protein 1.334512 3.035578 1.0775568 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved within P. aerophilum 0.000000e+00 0 1.322617e-02 2.192903e-04 5.798558e-02 -6.590847e-02 8.752227e-01 1 0 TRUE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5023184 0.4483858 U 0.4686274 0.6162291 13773 129 183815 183816 1 51 Divergent - + 0.000000 0 0.000000 0.00000000 1.334512 3.035578 1.0775568 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved within P. aerophilum 1.398411 3.000759 1.0551062 - - - hypothetical protein 0.000000e+00 0 4.083145e-03 6.192578e-03 6.557880e-02 3.750192e-01 1.781708e-01 0 0 FALSE TRUE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6232673 0.5854446 U 0.4686274 0.6162291 13773 129 183816 183817 1 53 Same + + 0.000000 0 0.000000 0.00000000 1.398411 3.000759 1.0551062 - - - hypothetical protein 1.380715 2.891643 1.0291224 2046 ATP sulfurylase (sulfate adenylyltransferase) P sulfate adenylyltransferase 0.000000e+00 0 3.131393e-04 3.744621e-03 7.007791e-02 2.520236e-01 1.972483e-02 0 19 TRUE TRUE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5701348 0.6377141 U 0.4686274 0.6162291 13773 129 183817 183818 1 -3 Same + + 2.197225 0 2.197225 2.19722458 1.380715 2.891643 1.0291224 2046 ATP sulfurylase (sulfate adenylyltransferase) P sulfate adenylyltransferase 1.301676 2.716322 0.9750762 - - - conserved hypothetical protein 1.864363e-02 1 6.247171e-03 1.058160e-02 1.886983e-01 5.452392e-01 1.351395e-01 19 1 TRUE TRUE 120 TRUE 2.9321590 1.6745314 0.5480306 2.9469979 0.6329203 0.6679717 0.6957759 0.5970160 U 0.4686274 0.8419484 13773 129 183818 183819 1 331 Same + + 0.000000 0 0.000000 -0.11778304 1.301676 2.716322 0.9750762 - - - conserved hypothetical protein 1.307993 3.235518 1.1247951 2181 Nitrate reductase gamma subunit C nitrate reductase gamma subunit (narI) 3.279005e-02 1 3.990459e-05 2.146929e-02 2.670605e-01 8.765880e-01 2.850733e-04 1 7 TRUE TRUE 121 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.6329203 0.7581838 0.8003462 0.6540676 U 0.4686274 0.5554237 13773 129 183819 183820 1 336 Same + + 0.000000 0 0.000000 0.00000000 1.307993 3.235518 1.1247951 2181 Nitrate reductase gamma subunit C nitrate reductase gamma subunit (narI) 1.479378 3.187912 1.0657804 - - - paREP13 0.000000e+00 0 2.937259e-02 -4.013006e-03 -7.641572e-02 -3.346843e-01 1.660399e+00 7 0 TRUE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4310306 0.4130911 U 0.4686274 0.6162291 13773 129 183820 183821 1 19 Same + + 0.000000 0 0.000000 0.00000000 1.479378 3.187912 1.0657804 - - - paREP13 1.303265 2.748000 0.9696739 247 Fe-S oxidoreductase C iron-sulfur binding reductase, degenerate 0.000000e+00 0 3.101581e-02 -4.145338e-03 2.600230e-02 -3.385599e-01 1.688205e+00 0 0 TRUE TRUE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4304348 0.4124111 U 0.4686274 0.6162291 13773 129 183821 183822 1 285 Same + + 0.000000 0 0.000000 0.00000000 1.303265 2.748000 0.9696739 247 Fe-S oxidoreductase C iron-sulfur binding reductase, degenerate 1.398553 3.060306 1.0839476 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 0.000000e+00 0 9.079941e-03 7.827032e-03 6.362202e-02 4.069922e-01 2.550134e-01 0 13 TRUE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6372481 0.5607931 U 0.4686274 0.6162291 13773 129 183822 183823 1 -3 Same + + 0.000000 0 0.000000 -0.36974703 1.398553 3.060306 1.0839476 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 1.310305 3.031383 1.0613498 2427 Uncharacterized conserved protein S conserved hypothetical protein 2.528213e-02 3 7.787702e-03 7.455001e-03 1.513640e-01 3.996710e-01 2.382459e-01 13 3 TRUE TRUE 125 TRUE 0.4469764 0.2466800 0.5480306 0.4469764 0.7136133 0.7123155 0.6351113 0.5674779 U 0.4686274 0.5403265 13773 129 183823 183824 1 13 Convergent + - 0.000000 0 0.000000 0.00000000 1.310305 3.031383 1.0613498 2427 Uncharacterized conserved protein S conserved hypothetical protein 1.349850 2.971776 1.0119181 - - - hypothetical protein 0.000000e+00 0 1.563818e-03 1.432636e-02 1.638794e-01 7.165782e-01 2.081742e-02 3 0 TRUE TRUE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7594547 0.6371410 U 0.4686274 0.6162291 13773 129 183824 183825 1 83 Divergent - + 0.000000 0 0.000000 0.00000000 1.349850 2.971776 1.0119181 - - - hypothetical protein 1.397392 3.022192 1.0733848 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C mercuric reductase 0.000000e+00 0 2.260163e-03 5.483410e-03 6.607229e-02 3.490410e-01 1.078944e-01 0 23 FALSE TRUE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6122901 0.6036927 U 0.4686274 0.6162291 13773 129 183825 183826 1 156 Same + + 0.000000 0 0.000000 0.00000000 1.397392 3.022192 1.0733848 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C mercuric reductase 1.380578 2.937157 1.0084863 - - - hypothetical protein 0.000000e+00 0 2.826946e-04 3.824080e-03 7.077931e-02 2.594550e-01 1.662378e-02 23 0 TRUE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5735786 0.6393728 U 0.4686274 0.6162291 13773 129 183826 183827 1 -15 Convergent + - 0.000000 0 0.000000 0.00000000 1.380578 2.937157 1.0084863 - - - hypothetical protein 1.537154 3.268051 1.1052041 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 0.000000e+00 0 2.451589e-02 -6.073127e-03 -4.432808e-02 -4.062577e-01 1.640680e+00 0 0 TRUE TRUE 127 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4182494 0.4136182 U 0.4686274 0.6162291 13773 129 183827 183828 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.537154 3.268051 1.1052041 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R flavoprotein reductase, conjectural 1.453675 3.581518 1.2099148 428 Predicted divalent heavy-metal cations transporter P conserved hypothetical protein 0.000000e+00 0 6.968667e-03 1.957274e-04 4.361550e-03 8.308591e-02 3.419961e-01 0 0 FALSE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177017 0.5271430 U 0.4686274 0.6162291 13773 129 183828 183829 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.453675 3.581518 1.2099148 428 Predicted divalent heavy-metal cations transporter P conserved hypothetical protein 1.490092 3.297159 1.1063942 - - - hypothetical protein 0.000000e+00 0 1.326210e-03 8.832167e-05 2.556043e-02 5.251828e-02 1.063871e-01 0 0 FALSE TRUE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187770 0.6042634 U 0.4686274 0.6162291 13773 129 183829 183830 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.490092 3.297159 1.1063942 - - - hypothetical protein 1.602453 3.566372 1.1186938 - - - hypothetical protein 0.000000e+00 0 1.262490e-02 5.845933e-03 1.432361e-01 3.860434e-01 1.801198e-01 0 0 FALSE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6285212 0.5850474 U 0.4686274 0.6162291 13773 129 183830 183831 1 95 Divergent - + 0.000000 0 0.000000 0.00000000 1.602453 3.566372 1.1186938 - - - hypothetical protein 1.398054 3.116759 1.0614079 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 0.000000e+00 0 4.177901e-02 -8.057411e-03 -1.241961e-01 -3.820430e-01 1.712221e+00 0 2 FALSE TRUE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4225799 0.4121339 U 0.4686274 0.6162291 13773 129 183831 183832 1 8 Same + + 0.000000 0 0.000000 0.00000000 1.398054 3.116759 1.0614079 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 1.459155 3.135018 1.0711881 2210 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.733331e-03 -4.140105e-04 8.824894e-03 -7.559861e-02 3.741345e-01 2 0 TRUE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4994825 0.5178169 U 0.4686274 0.6162291 13773 129 183832 183833 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.459155 3.135018 1.0711881 2210 Uncharacterized conserved protein S conserved hypothetical protein 1.477701 3.411742 1.1696672 2391 Predicted transporter component R conserved hypothetical protein 0.000000e+00 0 3.439683e-04 2.042006e-04 2.472992e-02 5.950257e-02 3.035029e-02 0 5 TRUE TRUE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185720 0.6329638 U 0.4686274 0.6162291 13773 129 183833 183834 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.477701 3.411742 1.1696672 2391 Predicted transporter component R conserved hypothetical protein 1.495703 3.418832 1.1444442 - - - hypothetical protein 0.000000e+00 0 3.240666e-04 1.165720e-03 3.759599e-02 1.652259e-01 1.722279e-02 5 0 TRUE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5365036 0.6392215 U 0.4686274 0.6162291 13773 129 183834 183835 1 -24 Same + + 0.000000 0 0.000000 0.00000000 1.495703 3.418832 1.1444442 - - - hypothetical protein 1.487235 3.345249 1.0901355 1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic sys R senC homolog 0.000000e+00 0 7.169743e-05 1.588191e-03 3.758373e-02 2.040595e-01 2.488501e-03 0 4 TRUE TRUE 127 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5509555 0.6493745 U 0.4686274 0.6162291 13773 129 183835 183836 1 105 Same + + 0.000000 0 0.000000 0.00000000 1.487235 3.345249 1.0901355 1999 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic sys R senC homolog 1.320835 3.043376 1.0151908 - - - conserved within P. aerophilum 0.000000e+00 0 2.768904e-02 -4.679530e-03 6.047472e-03 -3.825295e-01 1.748565e+00 4 0 TRUE TRUE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4220571 0.4115066 U 0.4686274 0.6162291 13773 129 183836 183837 1 5 Convergent + - 0.000000 0 0.000000 0.00000000 1.320835 3.043376 1.0151908 - - - conserved within P. aerophilum 1.427720 3.369964 1.1397821 - - - hypothetical protein 0.000000e+00 0 1.142429e-02 3.090707e-03 1.501163e-02 1.270520e-01 5.668252e-01 0 0 TRUE TRUE 129 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5234101 0.4816610 U 0.4686274 0.6162291 13773 129 183837 183838 1 96 Divergent - + 0.000000 0 0.000000 0.00000000 1.427720 3.369964 1.1397821 - - - hypothetical protein 1.476887 3.261063 1.0826206 320 Lipoate synthase H lipoic acid synthetase 0.000000e+00 0 2.417461e-03 -6.035359e-04 1.390841e-02 -4.750829e-02 2.271404e-01 0 41 FALSE TRUE 128 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5070499 0.5719932 U 0.4686274 0.6162291 13773 129 183838 183839 1 31 Same + + 2.564949 0 2.564949 -2.05085474 1.476887 3.261063 1.0826206 320 Lipoate synthase H lipoic acid synthetase 1.289608 2.768884 0.9640038 1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha C pyruvate dehydrogenase E1 alpha subunit 5.538024e-02 36 3.507348e-02 -4.124627e-03 3.733055e-02 -3.227996e-01 1.688205e+00 0 41 36 TRUE TRUE 129 TRUE 2.9291542 0.1953189 0.5480306 2.9443141 0.7743490 0.8711003 0.4347457 0.4124111 N 0.5492530 0.4560792 13773 129 183839 183840 1 0 Same + + 46.674626 0 65.719232 64.19133555 1.289608 2.768884 0.9640038 1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha C pyruvate dehydrogenase E1 alpha subunit 1.339069 2.895078 1.0262107 22 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta s C pyruvate dehydrogenase E1 beta subunit 3.322889e-01 36 2.446347e-03 1.817230e-02 1.987837e-01 8.069989e-01 1.642646e-02 C 36 44 TRUE TRUE 130 TRUE 2.0771956 2.0522099 0.5480306 2.1411556 0.7743490 1.2424137 0.7884734 0.6394805 Y 1.4497162 0.9364693 13773 129 183840 183841 1 0 Same + + 29.777454 0 62.916683 59.61121641 1.339069 2.895078 1.0262107 22 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta s C pyruvate dehydrogenase E1 beta subunit 1.354144 2.903410 1.0237930 508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and C pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) 2.408013e-01 42 2.272677e-04 1.092336e-02 1.404334e-01 6.298058e-01 6.997843e-03 C 44 42 TRUE TRUE 131 TRUE 2.1617868 2.0500148 0.5480306 2.1495760 0.7729307 1.1807211 0.7289167 0.6444474 Y 1.4497162 0.9356744 13773 129 183841 183842 1 -3 Same + + 25.935485 0 61.245552 55.72385375 1.354144 2.903410 1.0237930 508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and C pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase) 1.381975 3.075030 1.0645321 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) 1.052926e-01 42 7.745720e-04 6.750758e-03 8.788991e-02 4.287302e-01 3.364395e-02 C 42 54 TRUE TRUE 132 TRUE 2.2102051 2.0434403 0.5480306 2.1579474 0.7729307 1.0259018 0.6469509 0.6306472 Y 1.4497162 0.9348035 13773 129 183842 183843 1 -3 Same + + 1.504077 0 1.504077 -2.06751619 1.381975 3.075030 1.0645321 1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and re C pyruvate dehydrogenase E3 (dihydrolipoamide dehydrogenase) 1.442675 3.097238 1.0061463 321 Lipoate-protein ligase B H lipoate protein ligase B 3.118390e-02 20 3.684391e-03 6.052037e-04 1.576957e-02 -9.177711e-03 3.428943e-01 0 54 20 TRUE TRUE 133 TRUE 2.9322497 0.1947742 0.5480306 2.9467151 0.7777535 0.7398911 0.5188017 0.5266146 N 0.5492530 0.4558118 13773 129 183843 183844 1 61 Same + + 0.000000 0 0.000000 0.00000000 1.442675 3.097238 1.0061463 321 Lipoate-protein ligase B H lipoate protein ligase B 1.483919 3.192871 1.0732777 - - - hypothetical protein 0.000000e+00 0 1.701129e-03 -2.835757e-04 1.991574e-02 6.431819e-03 1.466602e-01 20 0 TRUE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193493 0.5938717 U 0.4686274 0.6162291 13773 129 183844 183845 1 261 Same + + 0.000000 0 0.000000 0.00000000 1.483919 3.192871 1.0732777 - - - hypothetical protein 1.517879 3.448035 1.1079735 - - - conserved within P. aerophilum 0.000000e+00 0 1.153273e-03 2.162562e-03 5.456197e-02 2.425715e-01 4.357616e-02 0 0 TRUE TRUE 135 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5664255 0.6264906 U 0.4686274 0.6162291 13773 129 183845 183846 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.517879 3.448035 1.1079735 - - - conserved within P. aerophilum 1.403009 3.076164 1.0441541 1741 Pirin-related protein R pirin homolog 0.000000e+00 0 1.319512e-02 -3.216854e-03 -2.215544e-02 -2.346412e-01 9.877583e-01 0 20 TRUE TRUE 136 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4553659 0.4404584 U 0.4686274 0.6162291 13773 129 183846 183847 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.403009 3.076164 1.0441541 1741 Pirin-related protein R pirin homolog 1.399126 3.017080 1.0176185 - - - hypothetical protein 0.000000e+00 0 1.507833e-05 2.528862e-03 5.129838e-02 1.659079e-01 1.913643e-03 20 0 TRUE TRUE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5370614 0.6504429 U 0.4686274 0.6162291 13773 129 183847 183848 1 121 Convergent + - 0.000000 0 0.000000 0.00000000 1.399126 3.017080 1.0176185 - - - hypothetical protein 1.432578 3.065229 0.9804827 - - - formate dehydrogenase protein fdhE 0.000000e+00 0 1.119056e-03 9.833739e-04 2.619705e-02 3.463287e-02 1.219366e-01 0 0 TRUE TRUE 138 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175633 0.6003415 U 0.4686274 0.6162291 13773 129 183848 183849 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.432578 3.065229 0.9804827 - - - formate dehydrogenase protein fdhE 1.443545 3.453513 1.1392855 - - - hypothetical protein 0.000000e+00 0 1.202615e-04 1.476586e-04 2.172162e-02 -1.731644e-03 1.041872e-02 0 0 FALSE TRUE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199710 0.6425621 U 0.4686274 0.6162291 13773 129 183849 183850 1 37 Same - - 0.000000 0 0.000000 0.00000000 1.443545 3.453513 1.1392855 - - - hypothetical protein 1.506129 3.161920 1.0715123 437 Fe-S-cluster-containing hydrogenase components 1 C formate dehydrogenase beta subunit 0.000000e+00 0 3.916806e-03 -4.295771e-04 2.316706e-02 1.164324e-02 2.707513e-01 0 4 FALSE TRUE 136 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187046 0.5531837 U 0.4686274 0.6162291 13773 129 183850 183851 1 6 Same - - 0.000000 0 0.000000 0.00000000 1.506129 3.161920 1.0715123 437 Fe-S-cluster-containing hydrogenase components 1 C formate dehydrogenase beta subunit 1.441328 3.147806 1.1188679 243 Anaerobic dehydrogenases, typically selenocysteine-containing C formate dehydrogenase alpha subunit 7.562104e-04 1 4.199137e-03 -5.508923e-04 6.945222e-03 0.000000e+00 2.935760e-01 C 4 1 FALSE TRUE 135 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.5199566 0.5445363 Y 1.4497162 0.7118045 13773 129 183851 183852 1 210 Same - - 0.000000 0 0.000000 0.00000000 1.441328 3.147806 1.1188679 243 Anaerobic dehydrogenases, typically selenocysteine-containing C formate dehydrogenase alpha subunit 1.483396 3.270195 1.0982228 1526 Uncharacterized protein required for formate dehydrogenase activity C formate dehydrogenase delta subunit 2.630347e-03 1 1.769684e-03 -3.220950e-04 1.931539e-02 0.000000e+00 1.550051e-01 C 1 13 FALSE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5063263 0.5199566 0.5915122 Y 1.4497162 0.7118045 13773 129 183852 183853 1 -21 Same - - 0.000000 0 0.000000 0.00000000 1.483396 3.270195 1.0982228 1526 Uncharacterized protein required for formate dehydrogenase activity C formate dehydrogenase delta subunit 1.590437 3.597336 1.1258192 - - - hypothetical protein 0.000000e+00 0 1.145785e-02 4.449859e-03 1.192630e-01 3.347868e-01 2.085187e-01 13 0 FALSE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6067323 0.5767479 U 0.4686274 0.6162291 13773 129 183853 183854 1 139 Divergent - + 0.000000 0 0.000000 0.00000000 1.590437 3.597336 1.1258192 - - - hypothetical protein 1.413890 3.026527 1.0050593 1832 Predicted CoA-binding protein R conserved hypothetical protein 0.000000e+00 0 3.116894e-02 -5.214553e-03 -8.575789e-02 -2.310225e-01 1.258943e+00 0 22 FALSE TRUE 132 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4566187 0.4258352 U 0.4686274 0.6162291 13773 129 183854 183855 1 29 Same + + 2.662588 0 2.662588 2.60339896 1.413890 3.026527 1.0050593 1832 Predicted CoA-binding protein R conserved hypothetical protein 1.464235 3.206119 1.1072739 1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family O conserved hypothetical protein 3.368335e-02 2 2.534576e-03 -4.816033e-04 1.195373e-02 -5.775561e-02 2.345146e-01 22 2 TRUE TRUE 133 TRUE 2.9244472 1.6981571 0.5480306 2.9399224 0.6838149 0.7648592 0.5045433 0.5687032 U 0.4686274 0.8460376 13773 129 183855 183856 1 19 Convergent + - 0.000000 0 0.000000 0.00000000 1.464235 3.206119 1.1072739 1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family O conserved hypothetical protein 1.445955 3.011945 0.9961085 - - - paREP8 0.000000e+00 0 3.341551e-04 -6.983505e-05 1.957746e-02 8.647027e-03 2.955338e-02 2 0 TRUE TRUE 134 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190270 0.6332836 U 0.4686274 0.6162291 13773 129 183856 183857 1 130 Divergent - + 0.000000 0 0.000000 0.00000000 1.445955 3.011945 0.9961085 - - - paREP8 1.414134 3.111511 1.0859890 2102 Predicted ATPases of PP-loop superfamily R conserved hypothetical protein 0.000000e+00 0 1.012583e-03 2.026194e-04 2.655714e-02 -1.098828e-02 9.660981e-02 0 13 FALSE TRUE 133 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182468 0.6082362 U 0.4686274 0.6162291 13773 129 183857 183858 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.414134 3.111511 1.0859890 2102 Predicted ATPases of PP-loop superfamily R conserved hypothetical protein 1.348139 2.970023 1.0134507 - - - paREP8 0.000000e+00 0 4.355233e-03 3.847141e-03 8.926845e-02 2.133385e-01 2.699532e-01 13 0 TRUE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5546694 0.5534105 U 0.4686274 0.6162291 13773 129 183858 183859 1 438 Convergent + - 0.000000 0 0.000000 0.00000000 1.348139 2.970023 1.0134507 - - - paREP8 1.451656 3.109448 1.0212581 2402 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 1.071567e-02 -2.716799e-05 -6.654170e-03 -7.757763e-02 7.884568e-01 0 1 TRUE TRUE 135 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4987732 0.4570748 U 0.4686274 0.6162291 13773 129 183859 183860 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.451656 3.109448 1.0212581 2402 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.416084 3.260653 1.0759889 - - - conserved within P. aerophilum 0.000000e+00 0 1.265374e-03 -9.290481e-06 2.379495e-02 -2.480373e-02 1.230109e-01 1 0 FALSE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5138646 0.6000329 U 0.4686274 0.6162291 13773 129 183860 183861 1 80 Same - - 0.000000 0 0.000000 0.00000000 1.416084 3.260653 1.0759889 - - - conserved within P. aerophilum 1.473136 3.409491 1.1039291 1846 Transcriptional regulators K transcriptional regulator, conjectural 0.000000e+00 0 3.254911e-03 -7.677178e-04 9.795810e-03 -7.441120e-02 2.994265e-01 0 3 FALSE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4999172 0.5419791 U 0.4686274 0.6162291 13773 129 183861 183862 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.473136 3.409491 1.1039291 1846 Transcriptional regulators K transcriptional regulator, conjectural 1.377090 2.929115 0.9892420 3945 Uncharacterized conserved protein S conserved hypothetical protein 5.631536e-04 1 9.224712e-03 -1.615549e-03 1.466797e-02 -1.798082e-01 8.187264e-01 3 1 FALSE TRUE 132 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.4706373 0.4531269 U 0.4686274 0.6162291 13773 129 183862 183863 1 213 Same - - 0.000000 0 0.000000 0.00000000 1.377090 2.929115 0.9892420 3945 Uncharacterized conserved protein S conserved hypothetical protein 1.623073 3.881899 1.1556832 - - - hypothetical protein 0.000000e+00 0 6.050731e-02 -1.275624e-02 -6.758276e-02 -5.497261e-01 2.283508e+00 1 0 FALSE TRUE 131 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3986804 0.4052564 U 0.4686274 0.6162291 13773 129 183863 183864 1 442 Same - - 0.000000 0 0.000000 0.00000000 1.623073 3.881899 1.1556832 - - - hypothetical protein 1.381527 3.321544 1.0910805 1846 Transcriptional regulators K transcriptional regulator, conjectural 0.000000e+00 0 5.834448e-02 -1.199462e-02 -1.819601e-01 -5.151522e-01 2.169008e+00 0 0 FALSE TRUE 130 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4037046 0.4063867 U 0.4686274 0.6162291 13773 129 183864 183865 1 56 Same - - 0.000000 0 0.000000 0.00000000 1.381527 3.321544 1.0910805 1846 Transcriptional regulators K transcriptional regulator, conjectural 1.398184 3.038462 1.0660191 2514 Predicted ring-cleavage extradiol dioxygenase R conserved hypothetical protein 0.000000e+00 0 2.774742e-04 3.717485e-03 5.899725e-02 2.501165e-01 1.803795e-02 0 14 FALSE TRUE 129 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5692958 0.6386975 U 0.4686274 0.6162291 13773 129 183865 183866 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.398184 3.038462 1.0660191 2514 Predicted ring-cleavage extradiol dioxygenase R conserved hypothetical protein 1.297921 2.819524 0.9876389 3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol R glcG homolog 5.755097e-03 2 1.005271e-02 8.166027e-03 1.688420e-01 4.152941e-01 2.620371e-01 14 2 FALSE TRUE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5508290 0.6415810 0.5566624 U 0.4686274 0.6162291 13773 129 183866 183867 1 -3 Same - - 0.000000 0 0.000000 -0.05918887 1.297921 2.819524 0.9876389 3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol R glcG homolog 1.326952 2.937303 1.0116287 604 NADPH:quinone reductase and related Zn-dependent oxidoreductases CR alcohol dehydrogenase (Zinc) 1.023438e-02 2 8.428146e-04 1.909812e-02 2.235491e-01 8.342311e-01 4.985249e-03 2 26 FALSE TRUE 127 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.6838149 0.6004284 0.7913054 0.6463622 U 0.4686274 0.5589164 13773 129 183867 183868 1 -3 Same - - 0.000000 0 0.000000 -1.90077538 1.326952 2.937303 1.0116287 604 NADPH:quinone reductase and related Zn-dependent oxidoreductases CR alcohol dehydrogenase (Zinc) 1.250110 2.608395 0.9014901 179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Q 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, conjectural 2.138653e-02 18 5.904772e-03 2.504778e-02 3.771658e-01 8.686254e-01 1.204435e-02 26 18 FALSE TRUE 126 TRUE 0.4469764 0.1969447 0.5480306 0.4469764 0.7781393 0.6861429 0.7989115 0.6419986 U 0.4686274 0.5245524 13773 129 183868 183869 1 68 Same - - 0.000000 0 0.000000 -0.61097853 1.250110 2.608395 0.9014901 179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Q 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, conjectural 1.479139 3.302477 1.1236431 2133 Glucose/sorbosone dehydrogenases G conserved hypothetical protein 6.387034e-03 11 5.245453e-02 -5.584896e-03 -1.454953e-01 -3.535192e-01 1.812051e+00 0 18 11 FALSE TRUE 125 TRUE 0.4469764 0.2305110 0.5480306 0.4469764 0.7764261 0.5625579 0.4274197 0.4106571 N 0.5492530 0.5439964 13773 129 183869 183870 1 101 Divergent - + 0.000000 0 0.000000 0.00000000 1.479139 3.302477 1.1236431 2133 Glucose/sorbosone dehydrogenases G conserved hypothetical protein 1.439133 3.074786 1.0542712 479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit C iron-sulfur protein, putative 0.000000e+00 0 1.600535e-03 -3.401778e-04 1.518687e-02 -7.410728e-03 1.431545e-01 0 11 0 FALSE TRUE 124 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193297 0.5946095 N 0.5492530 0.6245624 13773 129 183870 183871 1 -25 Convergent + - 0.000000 0 0.000000 0.00000000 1.439133 3.074786 1.0542712 479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit C iron-sulfur protein, putative 1.619914 3.522053 1.1136763 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 3.268204e-02 -2.066111e-03 6.831922e-02 -1.855862e-02 8.396916e-01 0 1 TRUE TRUE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5158384 0.4516044 U 0.4686274 0.6162291 13773 129 183871 183872 1 -3 Same - - 0.000000 0 0.000000 -0.07232066 1.619914 3.522053 1.1136763 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.321550 2.820879 0.9997251 2368 Aromatic ring hydroxylase Q 4-hydroxyphenylacetate-3-hydroxylase, conjectural 2.915931e-02 1 8.902125e-02 -2.188130e-02 -2.644115e-01 -7.993956e-01 3.197592e+00 1 9 FALSE TRUE 124 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.7296993 0.3832011 0.4005695 U 0.4686274 0.5573725 13773 129 183872 183873 1 285 Same - - 0.000000 0 0.000000 0.00000000 1.321550 2.820879 0.9997251 2368 Aromatic ring hydroxylase Q 4-hydroxyphenylacetate-3-hydroxylase, conjectural 1.643065 3.602775 1.0795956 2210 Uncharacterized conserved protein S conserved within P. aerophilum 0.000000e+00 0 1.033722e-01 -2.488731e-02 -2.197681e-01 -8.261106e-01 3.305531e+00 9 0 FALSE TRUE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3810518 0.3998860 U 0.4686274 0.6162291 13773 129 183873 183874 1 332 Divergent - + 0.000000 0 0.000000 0.00000000 1.643065 3.602775 1.0795956 2210 Uncharacterized conserved protein S conserved within P. aerophilum 1.479648 3.191031 1.0872750 3546 Mn-containing catalase P pseudocatalase 0.000000e+00 0 2.670518e-02 5.415794e-03 -7.209362e-03 3.345641e-01 3.181895e-01 0 6 FALSE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6063311 0.5356423 U 0.4686274 0.6162291 13773 129 183874 183875 1 4 Convergent + - 0.000000 0 0.000000 0.00000000 1.479648 3.191031 1.0872750 3546 Mn-containing catalase P pseudocatalase 1.540802 3.669063 1.1103851 3639 ABC-type phosphate/phosphonate transport system, permease component P transport protein, putative 0.000000e+00 0 3.739761e-03 2.526291e-03 6.854909e-02 2.596617e-01 1.273553e-01 P 6 0 TRUE TRUE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5737986 0.5986351 Y 1.4497162 0.7118045 13773 129 183875 183876 1 -6 Same - - 0.000000 0 0.000000 0.00000000 1.540802 3.669063 1.1103851 3639 ABC-type phosphate/phosphonate transport system, permease component P transport protein, putative 1.513705 3.394640 1.1074322 1136 ABC-type antimicrobial peptide transport system, ATPase component V iron (III) ABC transporter ATP-binding protein, putative 0.000000e+00 0 7.342208e-04 5.571300e-03 7.543866e-02 4.200897e-01 1.783239e-02 0 0 4 FALSE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6440930 0.6388731 N 0.5492530 0.6245624 13773 129 183876 183877 1 137 Divergent - + 0.000000 0 0.000000 0.00000000 1.513705 3.394640 1.1074322 1136 ABC-type antimicrobial peptide transport system, ATPase component V iron (III) ABC transporter ATP-binding protein, putative 1.485342 3.226206 1.0895051 3221 ABC-type phosphate/phosphonate transport system, periplasmic component P hypothetical protein 1.523153e-03 2 8.045030e-04 2.115432e-03 3.853821e-02 2.396665e-01 3.061829e-02 0 4 2 FALSE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4836464 0.5642404 0.6326945 N 0.5492530 0.6245624 13773 129 183877 183878 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.485342 3.226206 1.0895051 3221 ABC-type phosphate/phosphonate transport system, periplasmic component P hypothetical protein 1.435424 2.939284 0.9740132 2406 Protein distantly related to bacterial ferritins R conserved hypothetical protein 1.523153e-03 2 2.491813e-03 -5.421382e-04 1.211965e-02 -2.327470e-02 2.177300e-01 2 4 TRUE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4836464 0.5142676 0.5751052 U 0.4686274 0.6162291 13773 129 183878 183879 1 58 Same + + 0.000000 0 0.000000 0.00000000 1.435424 2.939284 0.9740132 2406 Protein distantly related to bacterial ferritins R conserved hypothetical protein 1.421209 2.966910 1.0204997 1433 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 2.020455e-04 4.820110e-04 2.803949e-02 1.185528e-02 2.309094e-02 4 0 TRUE TRUE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186829 0.6362005 U 0.4686274 0.6162291 13773 129 183879 183880 1 160 Same + + 0.000000 0 0.000000 0.00000000 1.421209 2.966910 1.0204997 1433 Uncharacterized conserved protein S hypothetical protein 1.465046 3.201706 1.1214751 665 Glycine/D-amino acid oxidases (deaminating) E conserved hypothetical protein 0.000000e+00 0 1.921687e-03 -4.121106e-04 1.407897e-02 -4.613947e-02 1.847086e-01 0 2 TRUE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5074646 0.5840258 U 0.4686274 0.6162291 13773 129 183880 183881 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.465046 3.201706 1.1214751 665 Glycine/D-amino acid oxidases (deaminating) E conserved hypothetical protein 1.661344 3.590164 1.1386743 - - - hypothetical protein 0.000000e+00 0 3.853276e-02 2.866561e-03 1.657211e-01 2.079669e-01 5.182232e-01 2 0 TRUE TRUE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5529587 0.4901366 U 0.4686274 0.6162291 13773 129 183881 183882 1 -45 Same - - 0.000000 0 0.000000 0.00000000 1.661344 3.590164 1.1386743 - - - hypothetical protein 1.270285 2.773619 0.9741628 1145 Ferredoxin C ferredoxin oxidoreductase, conjectural 0.000000e+00 0 1.529270e-01 -3.802376e-02 -4.524910e-01 -9.206866e-01 3.684161e+00 0 0 FALSE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3781748 0.3990644 U 0.4686274 0.6162291 13773 129 183882 183883 1 66 Same - - 0.000000 0 0.000000 0.00000000 1.270285 2.773619 0.9741628 1145 Ferredoxin C ferredoxin oxidoreductase, conjectural 1.375516 2.978272 1.0475524 - - - hypothetical protein 0.000000e+00 0 1.107348e-02 1.374192e-02 1.127370e-01 6.142917e-01 1.230109e-01 0 0 FALSE TRUE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7247155 0.6000329 U 0.4686274 0.6162291 13773 129 183883 183884 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.375516 2.978272 1.0475524 - - - hypothetical protein 1.354007 2.947917 1.0735409 - - - hypothetical protein 0.000000e+00 0 4.626433e-04 7.389380e-03 1.166005e-01 4.731251e-01 1.584159e-02 0 0 FALSE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6638072 0.6399079 U 0.4686274 0.6162291 13773 129 183884 183885 1 -33 Same - - 0.000000 0 0.000000 0.00000000 1.354007 2.947917 1.0735409 - - - hypothetical protein 1.316075 2.767352 0.9644184 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 0.000000e+00 0 1.438823e-03 1.317811e-02 1.972358e-01 6.813464e-01 2.262681e-02 0 2 FALSE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7470102 0.6365095 U 0.4686274 0.6162291 13773 129 183885 183886 1 55 Same - - 0.000000 0 0.000000 0.00000000 1.316075 2.767352 0.9644184 425 Predicted redox protein, regulator of disulfide bond formation O conserved hypothetical protein 1.438138 3.127943 1.0454736 2210 Uncharacterized conserved protein S conserved hypothetical protein 4.414517e-03 2 1.489941e-02 1.793625e-03 -4.345440e-03 3.261026e-02 7.534187e-01 2 11 FALSE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5396105 0.5174574 0.4592446 U 0.4686274 0.6162291 13773 129 183886 183887 1 -6 Divergent - + 0.000000 0 0.000000 0.00000000 1.438138 3.127943 1.0454736 2210 Uncharacterized conserved protein S conserved hypothetical protein 1.385421 2.990659 1.0217760 2154 Pterin-4a-carbinolamine dehydratase H 4a-hydroxytetrahydrobiopterin dehydratase 0.000000e+00 0 2.779069e-03 8.744483e-04 4.156845e-02 1.976547e-02 2.620371e-01 11 0 FALSE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176791 0.5566624 U 0.4686274 0.6162291 13773 129 183887 183888 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.385421 2.990659 1.0217760 2154 Pterin-4a-carbinolamine dehydratase H 4a-hydroxytetrahydrobiopterin dehydratase 1.418793 3.352008 1.1516514 1230 Co/Zn/Cd efflux system component P cation efflux system protein 0.000000e+00 0 1.113718e-03 2.150636e-03 3.752968e-02 1.261626e-01 1.009513e-01 0 0 34 TRUE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5233039 0.6063831 N 0.5492530 0.6245624 13773 129 183888 183889 1 68 Same + + 0.000000 0 0.000000 0.00000000 1.418793 3.352008 1.1516514 1230 Co/Zn/Cd efflux system component P cation efflux system protein 1.481716 3.398539 1.1200883 - - - paREP1 0.000000e+00 0 3.959233e-03 -9.885129e-04 8.815992e-03 -8.711227e-02 3.703885e-01 34 0 TRUE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4961454 0.5182644 U 0.4686274 0.6162291 13773 129 183889 183890 1 11 Convergent + - 0.000000 0 0.000000 0.00000000 1.481716 3.398539 1.1200883 - - - paREP1 1.327360 2.871127 1.0096848 1331 Highly conserved protein containing a thioredoxin domain O conserved hypothetical protein 0.000000e+00 0 2.382579e-02 -3.761063e-03 1.349549e-02 -3.316074e-01 1.574515e+00 0 24 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4322147 0.4149848 U 0.4686274 0.6162291 13773 129 183890 183891 1 162 Divergent - + 0.000000 0 0.000000 0.00000000 1.327360 2.871127 1.0096848 1331 Highly conserved protein containing a thioredoxin domain O conserved hypothetical protein 1.392398 3.105082 1.0365829 - - - paREP1 0.000000e+00 0 4.230018e-03 7.317246e-03 7.606308e-02 4.217400e-01 1.562160e-01 24 0 FALSE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6450419 0.5909581 U 0.4686274 0.6162291 13773 129 183891 183892 1 713 Convergent + - 0.000000 0 0.000000 0.00000000 1.392398 3.105082 1.0365829 - - - paREP1 1.433795 3.663050 1.2061398 - - - P. aerophilum family 79 protein 0.000000e+00 0 1.713634e-03 1.038201e-03 2.482477e-02 3.286765e-02 1.704809e-01 0 0 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174768 0.5875676 U 0.4686274 0.6162291 13773 129 183892 183893 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.433795 3.663050 1.2061398 - - - P. aerophilum family 79 protein 1.718508 3.850957 1.1506004 - - - P. aerophilum family 66 protein, interruption-C 0.000000e+00 0 8.106200e-02 -4.700783e-03 1.461842e-01 -6.662646e-02 1.089404e+00 0 0 FALSE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5019180 0.4337863 U 0.4686274 0.6162291 13773 129 183893 183894 1 594 Same - - 0.000000 0 0.000000 0.00000000 1.718508 3.850957 1.1506004 - - - P. aerophilum family 66 protein, interruption-C 1.427510 3.013995 0.9934479 - - - P. aerophilum family 66 protein, interruption-N 0.000000e+00 0 8.467999e-02 -6.379438e-03 -2.335998e-01 -1.414876e-01 1.255500e+00 0 0 FALSE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4792844 0.4259424 U 0.4686274 0.6162291 13773 129 183894 183895 1 419 Divergent - + 0.000000 0 0.000000 0.00000000 1.427510 3.013995 0.9934479 - - - P. aerophilum family 66 protein, interruption-N 1.388152 3.014273 1.0294393 4741 Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase F conserved hypothetical protein 0.000000e+00 0 1.549098e-03 1.510372e-03 4.710555e-02 7.469568e-02 1.368375e-01 0 0 FALSE TRUE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178886 0.5965788 U 0.4686274 0.6162291 13773 129 183895 183896 1 339 Same + + 0.000000 0 0.000000 0.00000000 1.388152 3.014273 1.0294393 4741 Predicted secreted endonuclease distantly related to archaeal Holliday junction resolvase F conserved hypothetical protein 1.411779 3.020746 1.0602383 - - - selenium binding protein, probable 0.000000e+00 0 5.582439e-04 2.505245e-03 4.385825e-02 1.525531e-01 4.784107e-02 0 3 TRUE TRUE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5311992 0.6247981 U 0.4686274 0.6162291 13773 129 183896 183897 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.411779 3.020746 1.0602383 - - - selenium binding protein, probable 1.412858 3.487151 1.1382069 - - - hypothetical protein 0.000000e+00 0 1.164975e-06 1.526519e-03 3.837197e-02 8.548429e-02 5.889944e-05 3 0 TRUE TRUE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176836 0.6554240 U 0.4686274 0.6162291 13773 129 183897 183898 1 39 Convergent + - 0.000000 0 0.000000 0.00000000 1.412858 3.487151 1.1382069 - - - hypothetical protein 1.369248 3.026826 1.0187989 1225 Peroxiredoxin O bacterioferritin comigratory protein homolog 0.000000e+00 0 1.901866e-03 3.165442e-03 7.111409e-02 1.917860e-01 1.414176e-01 0 38 TRUE TRUE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5466299 0.5954869 U 0.4686274 0.6162291 13773 129 183898 183899 1 208 Divergent - + 0.000000 0 0.000000 -3.49061503 1.369248 3.026826 1.0187989 1225 Peroxiredoxin O bacterioferritin comigratory protein homolog 1.359118 2.789519 0.9721743 2897 Rhodanese-related sulfurtransferase P thiosulfate sulfurtransferase 7.221967e-03 27 1.026212e-04 7.579970e-03 1.138519e-01 4.845657e-01 4.155945e-03 0 38 27 FALSE TRUE 121 FALSE 0.4469764 0.1875627 0.5480306 0.4469764 0.7761702 0.5718017 0.6679429 0.6472310 N 0.5492530 0.5303927 13773 129 183899 183900 1 28 Convergent + - 0.000000 0 0.000000 -0.11431683 1.359118 2.789519 0.9721743 2897 Rhodanese-related sulfurtransferase P thiosulfate sulfurtransferase 1.313744 2.767043 0.9981431 2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases PR Rieske iron sulfur protein, putative 1.054642e-03 2 2.058790e-03 1.270163e-02 1.957423e-01 6.647391e-01 3.336300e-02 27 2 TRUE TRUE 122 FALSE 0.4469764 0.2956327 0.5480306 0.4469764 0.6838149 0.4709759 0.7413343 0.6308211 U 0.4686274 0.5557741 13773 129 183900 183901 1 59 Divergent - + 0.000000 0 0.000000 0.00000000 1.313744 2.767043 0.9981431 2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases PR Rieske iron sulfur protein, putative 1.379305 2.813341 1.0107902 - - - hypothetical protein 0.000000e+00 0 4.298237e-03 9.922898e-03 1.018392e-01 5.359896e-01 1.048905e-01 2 0 FALSE TRUE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6892978 0.6045311 U 0.4686274 0.6162291 13773 129 183901 183902 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.379305 2.813341 1.0107902 - - - hypothetical protein 1.331173 2.888942 1.0195020 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 0.000000e+00 0 2.316638e-03 8.666437e-03 1.455740e-01 5.093706e-01 7.761120e-02 0 4 TRUE TRUE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6764170 0.6156404 U 0.4686274 0.6162291 13773 129 183902 183903 1 -10 Same + + 7.574969 0 12.827824 12.82782407 1.331173 2.888942 1.0195020 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C 2-oxoacid ferredoxin oxidoreductase alpha subunit 1.369842 2.904076 1.0360836 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 2.102834e-01 4 1.495284e-03 9.804025e-03 1.155552e-01 5.705483e-01 4.325634e-02 C 4 4 TRUE TRUE 123 TRUE 2.7258037 1.8739116 0.5480306 2.6891160 0.7323301 1.1488744 0.7079458 0.6266433 Y 1.4497162 0.9155223 13773 129 183903 183904 1 296 Same + + 0.000000 0 0.000000 0.00000000 1.369842 2.904076 1.0360836 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-oxoacid ferredoxin oxidoreductase beta subunit 1.576463 3.546035 1.1220628 - - - paREP5a 0.000000e+00 0 4.269227e-02 -1.019958e-02 -7.568340e-02 -5.392161e-01 2.182592e+00 4 0 TRUE TRUE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3995996 0.4059610 U 0.4686274 0.6162291 13773 129 183904 183905 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.576463 3.546035 1.1220628 - - - paREP5a 1.528190 3.190855 0.9609290 - - - paREP5b 0.000000e+00 0 2.330263e-03 9.605071e-03 1.082961e-01 5.467576e-01 2.285828e-02 0 0 TRUE TRUE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6973206 0.6363673 U 0.4686274 0.6162291 13773 129 183905 183906 1 119 Same + + 0.000000 0 0.000000 0.00000000 1.528190 3.190855 0.9609290 - - - paREP5b 1.469419 3.310634 1.1018818 3370 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 3.454075e-03 1.384354e-03 2.277150e-02 1.778115e-01 1.611071e-01 0 5 TRUE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5413488 0.5897354 U 0.4686274 0.6162291 13773 129 183906 183907 1 2 Same + + 0.000000 0 0.000000 -0.41711044 1.469419 3.310634 1.1018818 3370 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.386505 3.108073 1.0938893 114 Fumarase C fumarate hydratase class II 2.768716e-03 5 6.874730e-03 -1.169673e-03 1.692882e-02 -1.422492e-01 6.407370e-01 5 50 TRUE TRUE 127 TRUE 0.4469764 0.2400872 0.5480306 0.4469764 0.7448207 0.5102443 0.4791603 0.4712222 U 0.4686274 0.5382395 13773 129 183907 183908 1 412 Convergent + - 0.000000 0 0.000000 -7.65099717 1.386505 3.108073 1.0938893 114 Fumarase C fumarate hydratase class II 1.569681 3.386031 1.0767793 492 Thioredoxin reductase O thioredoxin reductase (trxB) 5.860375e-04 48 3.355340e-02 -7.675460e-03 -4.416551e-02 -4.296172e-01 1.791448e+00 0 50 48 TRUE TRUE 128 FALSE 0.4469764 0.1783521 0.5480306 0.4469764 0.7718122 0.4585188 0.4143693 0.4108873 N 0.5492530 0.5274687 13773 129 183908 183909 1 175 Same - - 0.000000 0 0.000000 -0.22439018 1.569681 3.386031 1.0767793 492 Thioredoxin reductase O thioredoxin reductase (trxB) 1.482461 2.924526 1.0228206 3350 Uncharacterized conserved protein S ribosomal protein L24, conjectural 1.190151e-02 2 7.607320e-03 3.674966e-03 3.062471e-02 3.092503e-01 1.762324e-01 48 2 FALSE TRUE 127 TRUE 0.4469764 0.2697711 0.5480306 0.4469764 0.6838149 0.6132969 0.5956452 0.5859323 U 0.4686274 0.5476247 13773 129 183909 183910 1 37 Same - - 0.000000 0 0.000000 0.00000000 1.482461 2.924526 1.0228206 3350 Uncharacterized conserved protein S ribosomal protein L24, conjectural 1.537662 3.085536 0.9479026 - - - hypothetical protein 0.000000e+00 0 3.047191e-03 2.680213e-03 6.852435e-02 2.714793e-01 1.034044e-01 2 0 FALSE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5801967 0.6048471 U 0.4686274 0.6162291 13773 129 183910 183911 1 104 Divergent - + 0.000000 0 0.000000 0.00000000 1.537662 3.085536 0.9479026 - - - hypothetical protein 1.452229 3.326521 1.0982687 - - - hypothetical protein 0.000000e+00 0 7.298871e-03 7.211321e-05 2.682594e-03 7.423685e-02 3.611060e-01 0 0 FALSE TRUE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178991 0.5209641 U 0.4686274 0.6162291 13773 129 183911 183912 1 270 Same + + 0.000000 0 0.000000 0.00000000 1.452229 3.326521 1.0982687 - - - hypothetical protein 1.568765 3.436794 1.0740291 3019 Predicted metal-binding protein R hypothetical protein 0.000000e+00 0 1.358069e-02 9.811225e-05 5.686788e-02 8.416200e-02 4.834678e-01 0 0 TRUE TRUE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176838 0.4957719 U 0.4686274 0.6162291 13773 129 183912 183913 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.568765 3.436794 1.0740291 3019 Predicted metal-binding protein R hypothetical protein 1.629837 3.895510 1.1765080 785 Cytochrome c biogenesis protein O cytochrome C-type biogenesis protein (ccdA), conjectural 0.000000e+00 0 3.729825e-03 2.094440e-02 3.115047e-01 7.279706e-01 1.187648e-02 0 0 TRUE TRUE 127 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7617075 0.6420390 U 0.4686274 0.6162291 13773 129 183913 183914 1 432 Same + + 0.000000 0 0.000000 0.00000000 1.629837 3.895510 1.1765080 785 Cytochrome c biogenesis protein O cytochrome C-type biogenesis protein (ccdA), conjectural 1.510920 3.775978 1.1201064 - - - hypothetical protein 0.000000e+00 0 1.414134e-02 1.062227e-02 7.307082e-02 5.157912e-01 1.171604e-01 0 0 TRUE TRUE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6811281 0.6014840 U 0.4686274 0.6162291 13773 129 183914 183915 1 121 Convergent + - 0.000000 0 0.000000 0.00000000 1.510920 3.775978 1.1201064 - - - hypothetical protein 1.312616 3.016075 0.9838714 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 0.000000e+00 0 3.932463e-02 -8.261005e-03 -3.594218e-02 -5.184028e-01 2.193945e+00 0 2 TRUE TRUE 129 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4032511 0.4058196 U 0.4686274 0.6162291 13773 129 183915 183916 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.312616 3.016075 0.9838714 4113 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.519243 3.235523 0.9679694 - - - hypothetical protein 0.000000e+00 0 4.269510e-02 -9.416124e-03 -1.265759e-01 -5.625969e-01 2.339515e+00 2 0 FALSE TRUE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3977588 0.4046968 U 0.4686274 0.6162291 13773 129 183916 183917 1 125 Divergent - + 0.000000 0 0.000000 0.00000000 1.519243 3.235523 0.9679694 - - - hypothetical protein 1.384224 3.175011 1.1301242 - - - conserved within P. aerophilum, degenerate 0.000000e+00 0 1.823020e-02 -4.557433e-03 -3.278292e-02 -3.415260e-01 1.369780e+00 0 0 FALSE TRUE 127 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4294364 0.4210285 U 0.4686274 0.6162291 13773 129 183917 183918 1 65 Same + + 0.000000 0 0.000000 0.00000000 1.384224 3.175011 1.1301242 - - - conserved within P. aerophilum, degenerate 1.417841 3.105563 1.1108843 2217 Cation transport ATPase P cation-transporting ATPase (P-type) 0.000000e+00 0 1.130068e-03 2.253655e-03 3.848958e-02 1.307338e-01 1.019290e-01 0 55 TRUE TRUE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5244228 0.6058668 U 0.4686274 0.6162291 13773 129 183918 183919 1 42 Same + + 0.000000 0 0.000000 0.00000000 1.417841 3.105563 1.1108843 2217 Cation transport ATPase P cation-transporting ATPase (P-type) 1.485489 3.329922 1.0969892 2445 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.576248e-03 -1.143988e-03 7.455251e-03 -9.692021e-02 4.185683e-01 55 0 TRUE TRUE 129 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4930484 0.5090246 U 0.4686274 0.6162291 13773 129 183919 183920 1 16 Same + + 0.000000 0 0.000000 0.00000000 1.485489 3.329922 1.0969892 2445 Uncharacterized conserved protein S conserved hypothetical protein 1.482890 3.251512 1.0792699 1708 Predicted nucleotidyltransferases R paREP11 0.000000e+00 0 6.754880e-06 1.073908e-03 3.286120e-02 1.591133e-01 6.031303e-04 0 0 TRUE TRUE 130 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5342321 0.6529329 U 0.4686274 0.6162291 13773 129 183920 183921 1 62 Convergent + - 0.000000 0 0.000000 0.00000000 1.482890 3.251512 1.0792699 1708 Predicted nucleotidyltransferases R paREP11 1.403041 3.396718 1.1667037 2245 Predicted membrane protein S hypothetical protein 0.000000e+00 0 6.375801e-03 -1.522927e-03 6.349003e-03 -1.490203e-01 5.960835e-01 0 0 TRUE TRUE 131 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4769023 0.4771498 U 0.4686274 0.6162291 13773 129 183921 183922 1 204 Divergent - + 0.000000 0 0.000000 0.00000000 1.403041 3.396718 1.1667037 2245 Predicted membrane protein S hypothetical protein 1.442531 3.040307 1.0904076 - - - hypothetical protein 0.000000e+00 0 1.559448e-03 4.284927e-04 2.001007e-02 -5.026478e-03 1.586521e-01 0 0 FALSE TRUE 130 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196716 0.5904345 U 0.4686274 0.6162291 13773 129 183922 183923 1 55 Convergent + - 0.000000 0 0.000000 0.00000000 1.442531 3.040307 1.0904076 - - - hypothetical protein 1.436334 3.472309 1.1796486 477 Permeases of the major facilitator superfamily GEPR transport protein, putative 0.000000e+00 0 3.839728e-05 1.334483e-04 2.267442e-02 -6.408259e-04 3.864392e-03 0 20 TRUE TRUE 131 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199869 0.6474175 U 0.4686274 0.6162291 13773 129 183923 183924 1 166 Same - - 0.000000 0 0.000000 0.00000000 1.436334 3.472309 1.1796486 477 Permeases of the major facilitator superfamily GEPR transport protein, putative 1.460737 3.418787 1.1784385 4756 Predicted cation transporter R conserved hypothetical protein 1.759678e-02 4 5.955047e-04 -1.407135e-04 1.873832e-02 -9.160041e-03 5.551213e-02 20 4 FALSE TRUE 130 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.6591545 0.5188424 0.6218902 U 0.4686274 0.6162291 13773 129 183924 183925 1 713 Divergent - + 0.000000 0 0.000000 0.00000000 1.460737 3.418787 1.1784385 4756 Predicted cation transporter R conserved hypothetical protein 1.620547 3.636324 1.1231104 675 Transposase and inactivated derivatives L paREP12, degenerate 0.000000e+00 0 2.553925e-02 1.580653e-03 1.116610e-01 1.674570e-01 5.061400e-01 4 0 FALSE TRUE 129 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5379038 0.4920423 U 0.4686274 0.6162291 13773 129 183925 183926 1 441 Convergent + - 0.000000 0 0.000000 0.00000000 1.620547 3.636324 1.1231104 675 Transposase and inactivated derivatives L paREP12, degenerate 1.406713 3.145549 1.0258568 - - - conserved hypothetical protein 0.000000e+00 0 4.572530e-02 -7.557869e-03 -1.352249e-01 -3.073491e-01 1.538133e+00 0 0 TRUE TRUE 130 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4383565 0.4158343 U 0.4686274 0.6162291 13773 129 183926 183927 1 138 Divergent - + 0.000000 0 0.000000 0.00000000 1.406713 3.145549 1.0258568 - - - conserved hypothetical protein 1.388733 2.973753 1.0528135 - - - hypothetical protein 0.000000e+00 0 3.232507e-04 2.799642e-03 5.837284e-02 1.744272e-01 2.799137e-02 0 0 FALSE TRUE 129 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5400419 0.6340416 U 0.4686274 0.6162291 13773 129 183927 183928 1 103 Same + + 0.000000 0 0.000000 0.00000000 1.388733 2.973753 1.0528135 - - - hypothetical protein 1.404541 2.979352 1.0767976 147 Anthranilate/para-aminobenzoate synthases component I EH hypothetical protein 0.000000e+00 0 2.498897e-04 2.935693e-03 5.066639e-02 1.877243e-01 1.994099e-02 0 0 TRUE TRUE 130 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5452392 0.6374861 U 0.4686274 0.6162291 13773 129 183928 183929 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.404541 2.979352 1.0767976 147 Anthranilate/para-aminobenzoate synthases component I EH hypothetical protein 1.351702 2.975510 1.0084479 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU type II secretion system protein, conjectural 0.000000e+00 0 2.791967e-03 4.670660e-03 9.501217e-02 2.827173e-01 1.592641e-01 0 1 TRUE TRUE 131 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5857086 0.5901897 U 0.4686274 0.6162291 13773 129 183929 183930 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.351702 2.975510 1.0084479 630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella bios NU type II secretion system protein, conjectural 1.404096 3.454968 1.1951689 2064 Flp pilus assembly protein TadC NU hypothetical protein 0.000000e+00 0 2.745086e-03 4.715072e-03 5.631035e-02 2.886073e-01 1.531974e-01 1 0 TRUE TRUE 132 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5886415 0.5924418 U 0.4686274 0.6162291 13773 129 183930 183931 1 66 Same + + 0.000000 0 0.000000 0.00000000 1.404096 3.454968 1.1951689 2064 Flp pilus assembly protein TadC NU hypothetical protein 1.435287 3.237900 1.0523926 - - - P. aerophilum family 453 0.000000e+00 0 9.728744e-04 7.617718e-04 2.462240e-02 2.222276e-02 1.004642e-01 0 0 TRUE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175383 0.6066151 U 0.4686274 0.6162291 13773 129 183931 183932 1 67 Convergent + - 0.000000 0 0.000000 0.00000000 1.435287 3.237900 1.0523926 - - - P. aerophilum family 453 1.363003 3.189419 1.0863858 - - - P. aerophilum family 453 0.000000e+00 0 5.224977e-03 1.423622e-03 5.656502e-02 4.176972e-02 4.195619e-01 0 0 TRUE TRUE 134 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183841 0.5088109 U 0.4686274 0.6162291 13773 129 183932 183933 1 56 Divergent - + 0.000000 0 0.000000 0.00000000 1.363003 3.189419 1.0863858 - - - P. aerophilum family 453 1.414990 3.107658 1.0162808 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 0.000000e+00 0 2.702715e-03 3.217619e-03 4.188349e-02 1.844377e-01 1.988215e-01 0 4 FALSE TRUE 133 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5437215 0.5803915 U 0.4686274 0.6162291 13773 129 183933 183934 1 -30 Same + + 0.000000 0 0.000000 0.00000000 1.414990 3.107658 1.0162808 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved hypothetical protein 1.457098 3.344225 1.0817281 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 0.000000e+00 0 1.773016e-03 -2.076661e-04 1.502704e-02 -3.905033e-02 1.685849e-01 4 0 TRUE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5093597 0.5880602 U 0.4686274 0.6162291 13773 129 183934 183935 1 -16 Convergent + - 0.000000 0 0.000000 0.00000000 1.457098 3.344225 1.0817281 1708 Predicted nucleotidyltransferases R conserved hypothetical protein 1.320371 2.931974 1.0585210 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter ATP-binding protein, putative 0.000000e+00 0 1.869419e-02 -7.474445e-04 5.551086e-02 -1.341494e-01 1.094216e+00 0 58 TRUE TRUE 135 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4808864 0.4333218 U 0.4686274 0.6162291 13773 129 183935 183936 1 83 Divergent - + 0.000000 0 0.000000 0.00000000 1.320371 2.931974 1.0585210 1136 ABC-type antimicrobial peptide transport system, ATPase component V ABC transporter ATP-binding protein, putative 1.446377 3.197837 1.0299687 - - - paREP5ab, internal deletion and authentic frameshift 0.000000e+00 0 1.587744e-02 6.572419e-04 -1.510890e-02 -4.127673e-02 8.881941e-01 58 0 FALSE TRUE 134 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5087566 0.4478833 U 0.4686274 0.6162291 13773 129 183936 183937 1 96 Convergent + - 0.000000 0 0.000000 0.00000000 1.446377 3.197837 1.0299687 - - - paREP5ab, internal deletion and authentic frameshift 1.504075 3.373064 1.1139801 - - - hypothetical protein 0.000000e+00 0 3.329146e-03 -2.642697e-04 2.463214e-02 2.449039e-02 2.360036e-01 0 0 TRUE TRUE 135 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173960 0.5682360 U 0.4686274 0.6162291 13773 129 183937 183938 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.504075 3.373064 1.1139801 - - - hypothetical protein 1.423926 3.151385 1.0841519 - - - conserved within P. aerophilum 0.000000e+00 0 6.423932e-03 -1.447027e-03 -1.313734e-03 -9.877790e-02 5.149136e-01 0 0 FALSE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4918315 0.4907464 U 0.4686274 0.6162291 13773 129 183938 183939 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.423926 3.151385 1.0841519 - - - conserved within P. aerophilum 1.393067 3.042114 1.0346168 - - - hypothetical protein 0.000000e+00 0 9.522732e-04 1.602034e-03 4.619241e-02 8.766004e-02 8.194620e-02 0 0 FALSE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177127 0.6136849 U 0.4686274 0.6162291 13773 129 183939 183940 1 36 Divergent - + 0.000000 0 0.000000 0.00000000 1.393067 3.042114 1.0346168 - - - hypothetical protein 1.552174 3.357382 1.0944538 608 Single-stranded DNA-specific exonuclease L conserved hypothetical protein part 1, authentic frameshift 0.000000e+00 0 2.531510e-02 -5.878158e-03 -3.083709e-02 -3.531758e-01 1.489037e+00 0 0 FALSE TRUE 132 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4276226 0.4173627 U 0.4686274 0.6162291 13773 129 183940 183941 1 -24 Same + + 0.000000 0 0.000000 0.00000000 1.552174 3.357382 1.0944538 608 Single-stranded DNA-specific exonuclease L conserved hypothetical protein part 1, authentic frameshift 1.425377 3.049794 1.0416300 608 Single-stranded DNA-specific exonuclease L conserved hypothetical protein part 2, authentic frameshift 0.000000e+00 0 1.607760e-02 -2.621943e-03 -3.399343e-02 -1.269136e-01 8.425070e-01 L 0 0 TRUE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4827091 0.4514144 Y 1.4497162 0.7118045 13773 129 183941 183942 1 -49 Convergent + - 0.000000 0 0.000000 0.00000000 1.425377 3.049794 1.0416300 608 Single-stranded DNA-specific exonuclease L conserved hypothetical protein part 2, authentic frameshift 1.368850 3.081893 1.0966477 616 Periplasmic serine proteases (ClpP class) OU protease IV, conjectural 0.000000e+00 0 3.195252e-03 2.147445e-03 6.142981e-02 1.135063e-01 2.496164e-01 0 0 TRUE TRUE 134 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5205943 0.5628925 U 0.4686274 0.6162291 13773 129 183942 183943 1 -19 Divergent - + 0.000000 0 0.000000 0.00000000 1.368850 3.081893 1.0966477 616 Periplasmic serine proteases (ClpP class) OU protease IV, conjectural 1.396237 3.138331 1.1013228 265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain O serine protease 0.000000e+00 0 7.500238e-04 4.552740e-03 6.439286e-02 3.050803e-01 4.551984e-02 0 7 FALSE TRUE 133 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5936207 0.6257919 U 0.4686274 0.6162291 13773 129 183943 183944 1 -3 Convergent + - 0.000000 0 0.000000 -0.14660347 1.396237 3.138331 1.1013228 265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain O serine protease 1.328372 2.835333 0.9856977 1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain S conserved hypothetical protein 2.114183e-04 7 4.605631e-03 6.785364e-03 1.307817e-01 3.977939e-01 1.736644e-01 7 9 TRUE TRUE 134 FALSE 0.4469764 0.2774393 0.5480306 0.4469764 0.7596462 0.4443167 0.6335969 0.5866463 U 0.4686274 0.5500440 13773 129 183944 183945 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.328372 2.835333 0.9856977 1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain S conserved hypothetical protein 1.416060 3.203858 1.0628580 - - - P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 7.689127e-03 4.346736e-03 3.629805e-02 2.209966e-01 3.835820e-01 9 0 FALSE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5574890 0.5159995 U 0.4686274 0.6162291 13773 129 183945 183946 1 63 Divergent - + 0.000000 0 0.000000 0.00000000 1.416060 3.203858 1.0628580 - - - P. aerophilum family 453, possible regulatory protein 1.400337 3.087048 1.0662294 624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases E peptidase family M20/M25/M40 0.000000e+00 0 2.472070e-04 1.803981e-03 4.527972e-02 1.059306e-01 2.722627e-02 0 11 FALSE TRUE 132 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5194395 0.6344003 U 0.4686274 0.6162291 13773 129 183946 183947 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.400337 3.087048 1.0662294 624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases E peptidase family M20/M25/M40 1.448840 3.166973 1.0873087 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 2.352587e-03 1.303277e-04 1.565826e-02 -2.985318e-02 2.397466e-01 0 11 0 TRUE TRUE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5120058 0.5661218 N 0.5492530 0.6245624 13773 129 183947 183948 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.448840 3.166973 1.0873087 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.332870 3.105544 1.0575958 - - - P. aerophilum family 453 0.000000e+00 0 1.344909e-02 3.025458e-04 5.993277e-02 -6.151399e-02 8.709201e-01 0 0 TRUE TRUE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5034120 0.4486372 U 0.4686274 0.6162291 13773 129 183948 183949 1 21 Same + + 0.000000 0 0.000000 0.00000000 1.332870 3.105544 1.0575958 - - - P. aerophilum family 453 1.329749 2.921974 1.0359797 - - - hypothetical protein 0.000000e+00 0 9.740293e-06 1.441757e-02 1.912154e-01 7.494123e-01 5.889944e-05 0 0 TRUE TRUE 135 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7666953 0.6554240 U 0.4686274 0.6162291 13773 129 183949 183950 1 187 Same + + 0.000000 0 0.000000 0.00000000 1.329749 2.921974 1.0359797 - - - hypothetical protein 1.350376 2.652701 1.1641298 - - - paREP8, degenerate 0.000000e+00 0 4.254808e-04 1.228804e-02 1.527493e-01 6.753386e-01 8.623467e-03 0 0 TRUE TRUE 136 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7448193 0.6437142 U 0.4686274 0.6162291 13773 129 183950 183951 1 255 Same + + 0.000000 0 0.000000 0.00000000 1.350376 2.652701 1.1641298 - - - paREP8, degenerate 1.406632 3.044956 1.0428376 500 SAM-dependent methyltransferases QR conserved hypothetical protein 0.000000e+00 0 3.164693e-03 4.521605e-03 5.277954e-02 2.670359e-01 1.873568e-01 0 7 TRUE TRUE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5764836 0.5834990 U 0.4686274 0.6162291 13773 129 183951 183952 1 5 Same + + 0.000000 0 0.000000 -0.13580154 1.406632 3.044956 1.0428376 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.426580 3.152890 1.0786613 1986 Uncharacterized conserved protein S conserved hypothetical protein 1.296813e-02 7 3.979482e-04 1.110627e-03 3.019888e-02 5.356551e-02 3.535439e-02 7 8 TRUE TRUE 138 TRUE 0.4469764 0.2789631 0.5480306 0.4469764 0.7596462 0.6226399 0.5187674 0.6298812 U 0.4686274 0.5505244 13773 129 183952 183953 1 28 Convergent + - 0.000000 0 0.000000 0.00000000 1.426580 3.152890 1.0786613 1986 Uncharacterized conserved protein S conserved hypothetical protein 1.345541 2.747353 1.0847804 - - - hypothetical protein 0.000000e+00 0 6.567417e-03 2.626438e-03 7.833756e-02 1.256637e-01 4.235482e-01 8 0 TRUE TRUE 139 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5231989 0.5080957 U 0.4686274 0.6162291 13773 129 183953 183954 1 265 Same - - 0.000000 0 0.000000 0.00000000 1.345541 2.747353 1.0847804 - - - hypothetical protein 1.605128 3.528594 1.1255324 - - - hypothetical protein 0.000000e+00 0 6.738555e-02 -1.627318e-02 -1.379671e-01 -7.044597e-01 2.822297e+00 0 0 FALSE TRUE 138 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3867651 0.4017316 U 0.4686274 0.6162291 13773 129 183954 183955 1 182 Same - - 0.000000 0 0.000000 0.00000000 1.605128 3.528594 1.1255324 - - - hypothetical protein 1.311976 2.825695 0.9879400 - - - paREP8 0.000000e+00 0 8.593801e-02 -2.143324e-02 -2.405256e-01 -8.023199e-01 3.211330e+00 0 0 FALSE TRUE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3829626 0.4004329 U 0.4686274 0.6162291 13773 129 183955 183956 1 436 Divergent - + 0.000000 0 0.000000 0.00000000 1.311976 2.825695 0.9879400 - - - paREP8 1.475249 3.394207 1.1231295 - - - hypothetical protein 0.000000e+00 0 2.665802e-02 -3.325961e-03 -6.606546e-02 -2.947010e-01 1.536230e+00 0 0 FALSE TRUE 136 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4418574 0.4159632 U 0.4686274 0.6162291 13773 129 183956 183957 1 465 Same + + 0.000000 0 0.000000 0.00000000 1.475249 3.394207 1.1231295 - - - hypothetical protein 1.499698 3.494587 1.1575954 - - - paREP1 0.000000e+00 0 5.977558e-04 1.152386e-03 3.869212e-02 1.624918e-01 3.449387e-02 0 0 TRUE TRUE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5352590 0.6302077 U 0.4686274 0.6162291 13773 129 183957 183958 1 895 Same + + 0.000000 0 0.000000 0.00000000 1.499698 3.494587 1.1575954 - - - paREP1 1.295578 2.810093 0.9614582 214 Pyridoxine biosynthesis enzyme H stress induced protein, conjectural 0.000000e+00 0 4.166506e-02 -7.526689e-03 -1.153727e-02 -4.831992e-01 2.132990e+00 0 33 TRUE TRUE 138 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4075311 0.4068150 U 0.4686274 0.6162291 13773 129 183958 183959 1 -3 Same + + 37.300049 0 74.108970 73.53424881 1.295578 2.810093 0.9614582 214 Pyridoxine biosynthesis enzyme H stress induced protein, conjectural 1.355637 2.934483 1.0265251 311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis H conserved hypothetical protein 5.779832e-01 31 3.607083e-03 1.492019e-02 1.568191e-01 7.130849e-01 4.262022e-02 H 33 31 TRUE TRUE 139 TRUE 2.1116198 2.0588056 0.5480306 2.1241672 0.7752555 1.2628730 0.7590053 0.6270113 Y 1.4497162 0.9367150 13773 129 183959 183960 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.355637 2.934483 1.0265251 311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis H conserved hypothetical protein 1.313745 2.803925 0.9540756 - - - paREP1 0.000000e+00 0 1.754920e-03 1.318057e-02 1.996792e-01 6.809588e-01 2.672209e-02 31 0 TRUE TRUE 140 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7465712 0.6346538 U 0.4686274 0.6162291 13773 129 183960 183961 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.313745 2.803925 0.9540756 - - - paREP1 1.497212 3.605536 1.1919972 - - - conserved within P. aerophilum 0.000000e+00 0 3.366004e-02 -6.306889e-03 -9.578858e-02 -4.439516e-01 1.955275e+00 0 0 TRUE FALSE 139 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4128419 0.4087775 U 0.4686274 0.6162291 13773 129 183961 183962 1 19 Same - - 0.000000 0 0.000000 0.00000000 1.497212 3.605536 1.1919972 - - - conserved within P. aerophilum 1.404334 3.226240 1.0696772 - - - hypothetical protein 0.000000e+00 0 8.626327e-03 -2.156197e-03 -4.180737e-03 -1.813956e-01 7.388346e-01 0 0 TRUE FALSE 138 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4696907 0.4609040 U 0.4686274 0.6162291 13773 129 183962 183963 1 90 Same - - 0.000000 0 0.000000 0.00000000 1.404334 3.226240 1.0696772 - - - hypothetical protein 1.359137 3.346044 1.1702030 - - - conserved hypothetical protein 0.000000e+00 0 2.042785e-03 4.341475e-03 8.748982e-02 2.710935e-01 1.268081e-01 0 0 TRUE FALSE 137 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5799602 0.5988589 U 0.4686274 0.6162291 13773 129 183963 183964 1 49 Divergent - + 0.000000 0 0.000000 0.00000000 1.359137 3.346044 1.1702030 - - - conserved hypothetical protein 1.575819 3.422707 1.1059855 - - - hypothetical protein 0.000000e+00 0 4.695117e-02 -1.147907e-02 -9.577673e-02 -5.947289e-01 2.386705e+00 0 0 TRUE FALSE 136 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3947473 0.4041403 U 0.4686274 0.6162291 13773 129 183964 183965 1 -16 Convergent + - 0.000000 0 0.000000 0.00000000 1.575819 3.422707 1.1059855 - - - hypothetical protein 1.426274 3.055489 1.0638809 1145 Ferredoxin C polyferredoxin 0.000000e+00 0 2.236367e-02 -3.125435e-03 -5.351975e-02 -1.284715e-01 9.484936e-01 0 0 FALSE FALSE 137 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4824675 0.4427224 U 0.4686274 0.6162291 13773 129 183965 183966 1 27 Same - - 0.000000 0 0.000000 0.00000000 1.426274 3.055489 1.0638809 1145 Ferredoxin C polyferredoxin 1.439000 3.091070 1.0876779 4670 Acyl CoA:acetate/3-ketoacid CoA transferase I coA transferase, putative 0.000000e+00 0 1.619618e-04 3.112819e-04 2.316497e-02 3.984547e-03 1.742481e-02 0 0 16 TRUE FALSE 136 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196118 0.6390912 N 0.5492530 0.6245624 13773 129 183966 183967 1 134 Divergent - + 0.000000 0 0.000000 0.00000000 1.439000 3.091070 1.0876779 4670 Acyl CoA:acetate/3-ketoacid CoA transferase I coA transferase, putative 1.446850 3.147456 1.0138607 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 1.011049e-02 3 6.161042e-05 5.630052e-05 2.105839e-02 -1.380014e-03 6.370563e-03 0 16 3 TRUE FALSE 135 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5976332 0.5199808 0.6451734 N 0.5492530 0.6245624 13773 129 183967 183968 1 -16 Same + + 5.010635 0 5.010635 4.95144642 1.446850 3.147456 1.0138607 2002 Regulators of stationary/sporulation gene expression K conserved hypothetical protein 1.523765 3.372059 1.0451670 1848 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.392617e-01 3 5.915986e-03 -3.287985e-04 3.014218e-02 3.487671e-02 3.428943e-01 3 4 FALSE FALSE 136 TRUE 2.8224171 1.7637291 0.5480306 2.8872874 0.7136133 1.0767792 0.5175781 0.5266146 U 0.4686274 0.8581552 13773 129 183968 183969 1 7 Convergent + - 0.000000 0 0.000000 -0.07232066 1.523765 3.372059 1.0451670 1848 Predicted nucleic acid-binding protein, contains PIN domain R conserved hypothetical protein 1.388571 3.068182 1.0501531 - - - paREP8 4.118834e-02 1 1.827742e-02 -4.546551e-03 -3.570082e-02 -3.281359e-01 1.328774e+00 4 1 FALSE FALSE 137 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.8108260 0.4333888 0.4230623 U 0.4686274 0.5573725 13773 129 183969 183970 1 312 Same - - 0.000000 0 0.000000 -0.07232066 1.388571 3.068182 1.0501531 - - - paREP8 1.472186 3.266246 1.1165881 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 8.054069e-03 1 6.991365e-03 -1.306231e-03 -3.459556e-03 -1.455759e-01 6.346085e-01 1 41 TRUE FALSE 136 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.5809077 0.4781623 0.4721311 U 0.4686274 0.5573725 13773 129 183970 183971 1 12 Same - - 0.000000 0 0.000000 0.00000000 1.472186 3.266246 1.1165881 1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) IQR short chain dehydrogenase 1.402350 3.265442 1.0828666 2427 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.877028e-03 -1.019736e-03 1.382481e-02 -1.120150e-01 4.602732e-01 41 0 TRUE FALSE 135 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4878022 0.5020955 U 0.4686274 0.6162291 13773 129 183971 183972 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.402350 3.265442 1.0828666 2427 Uncharacterized conserved protein S conserved hypothetical protein 1.349413 2.945366 1.0170575 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R conserved hypothetical protein 0.000000e+00 0 2.802336e-03 5.001417e-03 9.951834e-02 3.081925e-01 1.496140e-01 0 4 TRUE FALSE 134 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5953911 0.5933123 U 0.4686274 0.6162291 13773 129 183972 183973 1 72 Same - - 0.000000 0 0.000000 0.00000000 1.349413 2.945366 1.0170575 446 Uncharacterized NAD(FAD)-dependent dehydrogenases R conserved hypothetical protein 1.456310 3.657662 1.2428926 3301 Formate-dependent nitrite reductase, membrane component P molybdopterin oxidoreductase, membrane subunit 0.000000e+00 0 1.142710e-02 -5.014839e-04 -1.147515e-02 -1.115249e-01 8.538157e-01 4 0 TRUE FALSE 133 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4879186 0.4498973 U 0.4686274 0.6162291 13773 129 183973 183974 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.456310 3.657662 1.2428926 3301 Formate-dependent nitrite reductase, membrane component P molybdopterin oxidoreductase, membrane subunit 1.511137 3.124213 1.0127483 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 0.000000e+00 0 3.005941e-03 2.937887e-04 3.317571e-02 8.106919e-02 1.807718e-01 0 0 0 TRUE FALSE 132 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177429 0.5848968 N 0.5492530 0.6245624 13773 129 183974 183975 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.511137 3.124213 1.0127483 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 1.420734 3.131720 1.0866802 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit part 2, authentic frameshift 0.000000e+00 0 8.172669e-03 -1.831682e-03 -7.356163e-03 -1.194245e-01 6.056017e-01 C 0 0 TRUE FALSE 131 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4853372 0.4761308 Y 1.4497162 0.7118045 13773 129 183975 183976 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.420734 3.131720 1.0866802 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit part 2, authentic frameshift 1.415721 3.093811 1.0865642 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit part 1, authentic frameshift 0.000000e+00 0 2.512976e-05 1.093659e-03 3.436948e-02 5.406380e-02 2.191648e-03 C 0 0 TRUE FALSE 130 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187593 0.6499017 Y 1.4497162 0.7118045 13773 129 183976 183977 1 95 Same - - 0.000000 0 0.000000 0.00000000 1.415721 3.093811 1.0865642 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit part 1, authentic frameshift 1.623658 3.348491 1.0777559 - - - hypothetical protein 0.000000e+00 0 4.323771e-02 -6.145009e-03 2.101752e-02 -2.320402e-01 1.344745e+00 0 0 TRUE FALSE 129 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4563070 0.4225072 U 0.4686274 0.6162291 13773 129 183977 183978 1 35 Same - - 0.000000 0 0.000000 0.00000000 1.623658 3.348491 1.0777559 - - - hypothetical protein 1.427038 3.256597 1.1152006 - - - conserved hypothetical protein 0.000000e+00 0 3.865925e-02 -4.195444e-03 -1.021708e-01 -1.371462e-01 1.111948e+00 0 0 TRUE FALSE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4800265 0.4321685 U 0.4686274 0.6162291 13773 129 183978 183979 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.427038 3.256597 1.1152006 - - - conserved hypothetical protein 1.680742 3.911576 1.1493915 - - - hypothetical protein 0.000000e+00 0 6.436561e-02 -5.585707e-03 8.750256e-02 -1.456595e-01 1.233242e+00 0 0 TRUE FALSE 127 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4777858 0.4271864 U 0.4686274 0.6162291 13773 129 183979 183980 1 275 Divergent - + 0.000000 0 0.000000 0.00000000 1.680742 3.911576 1.1493915 - - - hypothetical protein 1.423777 3.224928 1.0515196 - - - paREP5ab, internal deletion and authentic frameshift 0.000000e+00 0 6.603087e-02 -6.333605e-03 -1.849607e-01 -1.794996e-01 1.312897e+00 0 0 TRUE FALSE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4710403 0.4237791 U 0.4686274 0.6162291 13773 129 183980 183981 1 20 Convergent + - 0.000000 0 0.000000 0.00000000 1.423777 3.224928 1.0515196 - - - paREP5ab, internal deletion and authentic frameshift 1.611162 3.551840 1.1308714 - - - hypothetical protein 0.000000e+00 0 3.511316e-02 -4.412123e-03 3.203748e-02 -1.657030e-01 1.149487e+00 0 0 FALSE FALSE 127 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4732939 0.4305738 U 0.4686274 0.6162291 13773 129 183981 183982 1 15 Same - - 0.000000 0 0.000000 0.00000000 1.611162 3.551840 1.1308714 - - - hypothetical protein 1.539793 3.266599 1.1612734 - - - hypothetical protein 0.000000e+00 0 5.093557e-03 1.412368e-02 1.408967e-01 6.315728e-01 2.929010e-02 0 0 TRUE FALSE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7297619 0.6334684 U 0.4686274 0.6162291 13773 129 183982 183983 1 46 Same - - 0.000000 0 0.000000 0.00000000 1.539793 3.266599 1.1612734 - - - hypothetical protein 1.413193 3.101166 1.0949745 - - - paREP6 0.000000e+00 0 1.602756e-02 -3.376862e-03 -3.488514e-02 -2.026730e-01 9.954005e-01 0 0 TRUE FALSE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4632313 0.4395482 U 0.4686274 0.6162291 13773 129 183983 183984 1 -21 Same - - 0.000000 0 0.000000 0.00000000 1.413193 3.101166 1.0949745 - - - paREP6 1.412414 3.074276 1.0715413 - - - conserved hypothetical protein 0.000000e+00 0 6.077939e-07 1.488994e-03 3.830023e-02 8.237676e-02 3.769564e-05 0 0 TRUE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177101 0.6555210 U 0.4686274 0.6162291 13773 129 183984 183985 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.412414 3.074276 1.0715413 - - - conserved hypothetical protein 1.464464 3.475481 1.1499874 - - - paREP6 0.000000e+00 0 2.709237e-03 -5.095004e-04 1.135586e-02 -6.278445e-02 2.565660e-01 0 0 TRUE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5031809 0.5600453 U 0.4686274 0.6162291 13773 129 183985 183986 1 228 Divergent - + 0.000000 0 0.000000 0.00000000 1.464464 3.475481 1.1499874 - - - paREP6 1.461397 3.238656 1.1150198 - - - P. aerophilum family 1964 protein 0.000000e+00 0 9.405465e-06 1.307659e-04 2.208693e-02 4.169020e-02 5.660236e-04 0 0 TRUE FALSE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183393 0.6530578 U 0.4686274 0.6162291 13773 129 183986 183987 1 7 Convergent + - 0.000000 0 0.000000 0.00000000 1.461397 3.238656 1.1150198 - - - P. aerophilum family 1964 protein 1.422733 3.077684 1.0346589 5550 Predicted aspartyl protease O conserved within P. aerophilum 0.000000e+00 0 1.494910e-03 -2.867196e-04 1.921704e-02 -3.784642e-02 1.514004e-01 0 0 FALSE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5094931 0.5927845 U 0.4686274 0.6162291 13773 129 183987 183988 1 49 Same - - 0.000000 0 0.000000 0.00000000 1.422733 3.077684 1.0346589 5550 Predicted aspartyl protease O conserved within P. aerophilum 1.552959 3.364299 1.1044575 - - - conserved within P. aerophilum 0.000000e+00 0 1.695877e-02 -2.910864e-03 1.081382e-02 -1.482193e-01 9.041777e-01 0 0 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4774080 0.4460064 U 0.4686274 0.6162291 13773 129 183988 183989 1 93 Same - - 0.000000 0 0.000000 0.00000000 1.552959 3.364299 1.1044575 - - - conserved within P. aerophilum 1.451433 3.336794 1.0994001 - - - hypothetical protein 0.000000e+00 0 1.030754e-02 4.058882e-06 -5.411540e-03 7.295167e-02 4.325864e-01 0 0 TRUE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179775 0.5070154 U 0.4686274 0.6162291 13773 129 183989 183990 1 412 Divergent - + 0.000000 0 0.000000 0.00000000 1.451433 3.336794 1.0994001 - - - hypothetical protein 1.464901 3.174646 1.1027993 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit 0.000000e+00 0 1.813852e-04 5.398161e-07 2.120736e-02 2.115079e-02 1.489037e-02 0 8 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5175851 0.6404563 U 0.4686274 0.6162291 13773 129 183990 183991 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.464901 3.174646 1.1027993 243 Anaerobic dehydrogenases, typically selenocysteine-containing C molybdopterin oxidoreductase, molybdopterin binding subunit 1.528964 3.317503 1.0929392 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 0.000000e+00 0 4.104067e-03 1.047819e-03 4.780656e-02 1.468805e-01 2.050290e-01 C 8 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5297381 0.5780796 Y 1.4497162 0.7118045 13773 129 183991 183992 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.528964 3.317503 1.0929392 437 Fe-S-cluster-containing hydrogenase components 1 C molybdopterin oxidoreductase, iron-sulfur binding subunit 1.481566 3.692880 1.1869757 3301 Formate-dependent nitrite reductase, membrane component P molybdopterin oxidoreductase, membrane subunit 0.000000e+00 0 2.246559e-03 2.340547e-03 3.513518e-02 2.535621e-01 8.639900e-02 0 0 1 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5714096 0.6124500 N 0.5492530 0.6245624 13773 129 183992 183993 1 120 Same + + 0.000000 0 0.000000 0.00000000 1.481566 3.692880 1.1869757 3301 Formate-dependent nitrite reductase, membrane component P molybdopterin oxidoreductase, membrane subunit 1.501455 3.165412 1.0494619 - - - paREP1 0.000000e+00 0 3.955719e-04 1.510521e-03 4.245166e-02 1.944459e-01 1.887197e-02 1 0 FALSE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5477285 0.6382319 U 0.4686274 0.6162291 13773 129 183993 183994 1 70 Convergent + - 0.000000 0 0.000000 0.00000000 1.501455 3.165412 1.0494619 - - - paREP1 1.486482 3.231015 1.1060169 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 2.241822e-04 1.756640e-03 3.803908e-02 2.161827e-01 9.056378e-03 0 2 FALSE FALSE 124 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5557145 0.6434772 U 0.4686274 0.6162291 13773 129 183994 183995 1 238 Same - - 0.000000 0 0.000000 0.00000000 1.486482 3.231015 1.1060169 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.413306 3.016774 1.0635902 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.134242e-03 2 5.354716e-03 -1.336433e-03 5.668743e-03 -1.182400e-01 4.920436e-01 2 3 TRUE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4743646 0.4855737 0.4938708 U 0.4686274 0.6162291 13773 129 183995 183996 1 33 Same - - 0.000000 0 0.000000 0.00000000 1.413306 3.016774 1.0635902 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.554449 3.599203 1.1343807 517 FOG: CBS domain R conserved protein with CBS domains 5.374391e-03 3 1.992142e-02 -3.925080e-03 -1.867968e-03 -2.139993e-01 1.084603e+00 3 9 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5484663 0.4604317 0.4341358 U 0.4686274 0.6162291 13773 129 183996 183997 1 -61 Same - - 0.000000 0 0.000000 0.00000000 1.554449 3.599203 1.1343807 517 FOG: CBS domain R conserved protein with CBS domains 1.553896 3.610828 1.1825718 477 Permeases of the major facilitator superfamily GEPR sugar transporter, putative 0.000000e+00 0 3.067872e-07 1.056358e-02 1.439609e-01 5.755241e-01 5.300950e-06 9 0 TRUE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7107558 0.6558673 U 0.4686274 0.6162291 13773 129 183997 183998 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.553896 3.610828 1.1825718 477 Permeases of the major facilitator superfamily GEPR sugar transporter, putative 1.375583 2.933100 1.0421685 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 0.000000e+00 0 3.179540e-02 -7.770724e-03 -8.220700e-02 -4.737900e-01 1.912585e+00 0 38 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4090915 0.4095588 U 0.4686274 0.6162291 13773 129 183998 183999 1 235 Same - - 0.000000 0 0.000000 -0.79095930 1.375583 2.933100 1.0421685 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase 1.323962 2.957069 1.0574064 460 Homoserine dehydrogenase E homoserine dehydrogenase 1.396676e-02 13 2.664678e-03 9.660494e-03 1.603338e-01 5.539551e-01 6.768783e-02 0 38 13 TRUE FALSE 119 TRUE 0.4469764 0.2184029 0.5480306 0.4469764 0.7781369 0.6327344 0.7004330 0.6184898 N 0.5492530 0.5401670 13773 129 183999 184000 1 49 Divergent - + 0.000000 0 0.000000 0.00000000 1.323962 2.957069 1.0574064 460 Homoserine dehydrogenase E homoserine dehydrogenase 1.419458 3.163189 1.0619968 - - - paREP1 0.000000e+00 0 9.119330e-03 4.069526e-03 2.967181e-02 2.005114e-01 4.346078e-01 13 0 TRUE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5501360 0.5062177 U 0.4686274 0.6162291 13773 129 184000 184001 1 90 Convergent + - 0.000000 0 0.000000 0.00000000 1.419458 3.163189 1.0619968 - - - paREP1 1.599937 3.363366 1.0635383 2445 Uncharacterized conserved protein S paREP11 0.000000e+00 0 3.257295e-02 -4.743809e-03 1.871726e-02 -1.956463e-01 1.189322e+00 0 0 FALSE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4652432 0.4286704 U 0.4686274 0.6162291 13773 129 184001 184002 1 47 Same - - 0.000000 0 0.000000 0.00000000 1.599937 3.363366 1.0635383 2445 Uncharacterized conserved protein S paREP11 1.484258 3.158576 1.0622991 - - - conserved within P. aerophilum 0.000000e+00 0 1.338165e-02 4.881981e-03 2.452674e-02 3.481840e-01 2.127454e-01 0 0 TRUE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6120157 0.5756211 U 0.4686274 0.6162291 13773 129 184002 184003 1 312 Divergent - + 0.000000 0 0.000000 0.00000000 1.484258 3.158576 1.0622991 - - - conserved within P. aerophilum 1.615402 3.263455 1.0107660 - - - hypothetical protein 0.000000e+00 0 1.719860e-02 5.390225e-03 1.493287e-01 3.583884e-01 2.367498e-01 0 0 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6153315 0.5679532 U 0.4686274 0.6162291 13773 129 184003 184004 1 61 Same + + 0.000000 0 0.000000 0.00000000 1.615402 3.263455 1.0107660 - - - hypothetical protein 1.445123 3.153118 1.0653918 - - - hypothetical protein 0.000000e+00 0 2.899488e-02 -1.028329e-03 -5.949602e-02 3.140165e-02 7.296280e-01 0 0 FALSE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174026 0.4617333 U 0.4686274 0.6162291 13773 129 184004 184005 1 41 Convergent + - 0.000000 0 0.000000 0.00000000 1.445123 3.153118 1.0653918 - - - hypothetical protein 1.411964 3.112881 1.0705154 136 Aspartate-semialdehyde dehydrogenase E aspartate-semialdehyde dehydrogenase (asd) 0.000000e+00 0 1.099483e-03 2.472146e-04 2.747628e-02 -1.037690e-02 1.083991e-01 0 60 FALSE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184455 0.6034335 U 0.4686274 0.6162291 13773 129 184005 184006 1 13 Same - - 0.000000 0 0.000000 -0.06317890 1.411964 3.112881 1.0705154 136 Aspartate-semialdehyde dehydrogenase E aspartate-semialdehyde dehydrogenase (asd) 1.413216 3.144748 1.0880329 527 Aspartokinases E aspartate kinase 2.855583e-03 1 1.566214e-06 1.505256e-03 3.809092e-02 8.324081e-02 1.154429e-04 E 60 1 TRUE FALSE 118 TRUE 0.4469764 0.3037120 0.5480306 0.4469764 0.6329203 0.5112366 0.5176918 0.6549470 Y 1.4497162 0.6603634 13773 129 184006 184007 1 -3 Same - - 2.793208 0 2.793208 2.79320801 1.413216 3.144748 1.0880329 527 Aspartokinases E aspartate kinase 1.414485 3.083992 1.0488236 498 Threonine synthase E threonine synthase 1.145043e-02 1 1.610623e-06 1.409028e-03 3.697045e-02 7.498193e-02 3.392608e-04 E 1 32 TRUE FALSE 117 TRUE 2.9180123 1.7201207 0.5480306 2.9337967 0.6329203 0.6079966 0.5178783 0.6537679 Y 1.4497162 0.8968985 13773 129 184007 184008 1 468 Divergent - + 0.000000 0 0.000000 0.00000000 1.414485 3.083992 1.0488236 498 Threonine synthase E threonine synthase 1.346657 3.093543 1.0665340 - - - hypothetical protein 0.000000e+00 0 4.600684e-03 3.865585e-03 9.033347e-02 2.123472e-01 2.886073e-01 32 0 TRUE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5541521 0.5474398 U 0.4686274 0.6162291 13773 129 184008 184009 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.346657 3.093543 1.0665340 - - - hypothetical protein 1.392955 3.046548 1.0515282 2 Acetylglutamate semialdehyde dehydrogenase E N-acetyl-gamma-glutamyl-phosphate reductase (argC) 0.000000e+00 0 2.143562e-03 6.120525e-03 7.311531e-02 3.797630e-01 1.078944e-01 0 49 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6244243 0.6036927 U 0.4686274 0.6162291 13773 129 184009 184010 1 -3 Same + + 37.124095 0 92.602801 89.99264495 1.392955 3.046548 1.0515282 2 Acetylglutamate semialdehyde dehydrogenase E N-acetyl-gamma-glutamyl-phosphate reductase (argC) 1.479696 3.288972 1.1109807 548 Acetylglutamate kinase E acetylglutamate kinase (argB) 2.815304e-01 48 7.523935e-03 -1.653962e-03 -5.238878e-03 -1.715293e-01 6.985008e-01 E 49 48 FALSE FALSE 118 TRUE 2.1201031 2.0742575 0.5480306 2.0542348 0.7718122 1.2134042 0.4727681 0.4650492 Y 1.4497162 0.9378107 13773 129 184010 184011 1 71 Same + + 0.000000 0 0.000000 0.00000000 1.479696 3.288972 1.1109807 548 Acetylglutamate kinase E acetylglutamate kinase (argB) 1.493542 3.071060 1.0267087 - - - hypothetical protein 0.000000e+00 0 1.917160e-04 1.192952e-03 3.716330e-02 1.668032e-01 9.650084e-03 48 0 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5374817 0.6430012 U 0.4686274 0.6162291 13773 129 184011 184012 1 244 Same + + 0.000000 0 0.000000 0.00000000 1.493542 3.071060 1.0267087 - - - hypothetical protein 1.392024 2.994696 1.0473833 137 Argininosuccinate synthase E argininosuccinate synthase (argG) 0.000000e+00 0 1.030594e-02 -2.502356e-03 -4.081196e-03 -2.226399e-01 8.910896e-01 0 48 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4589246 0.4474444 U 0.4686274 0.6162291 13773 129 184012 184013 1 49 Same + + 0.000000 0 0.000000 0.00000000 1.392024 2.994696 1.0473833 137 Argininosuccinate synthase E argininosuccinate synthase (argG) 1.350950 2.754359 1.0419643 - - - hypothetical protein 0.000000e+00 0 1.687104e-03 5.963216e-03 1.071311e-01 3.725507e-01 8.238618e-02 48 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6218293 0.6134641 U 0.4686274 0.6162291 13773 129 184013 184014 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.350950 2.754359 1.0419643 - - - hypothetical protein 1.390523 3.100962 1.0777570 165 Argininosuccinate lyase E argininosuccinate lyase (argH) 0.000000e+00 0 1.566041e-03 6.113996e-03 7.601279e-02 3.843777e-01 7.381042e-02 0 52 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6273431 0.6167268 U 0.4686274 0.6162291 13773 129 184014 184015 1 254 Convergent + - 0.000000 0 0.000000 -0.18866795 1.390523 3.100962 1.0777570 165 Argininosuccinate lyase E argininosuccinate lyase (argH) 1.578354 3.864240 1.2551062 3371 Predicted membrane protein S conserved hypothetical protein 1.466307e-02 3 3.528065e-02 -7.728149e-03 -3.809650e-02 -4.100285e-01 1.744508e+00 52 3 FALSE FALSE 123 FALSE 0.4469764 0.2739982 0.5480306 0.4469764 0.7136133 0.6368474 0.4173932 0.4116236 U 0.4686274 0.5489586 13773 129 184015 184016 1 114 Divergent - + 0.000000 0 0.000000 0.00000000 1.578354 3.864240 1.2551062 3371 Predicted membrane protein S conserved hypothetical protein 1.423054 3.100155 1.0850778 3842 ABC-type spermidine/putrescine transport systems, ATPase components E spermidine/putrescine transport ATP-binding protein 2.897430e-03 3 2.411805e-02 -3.597900e-03 -6.022535e-02 -1.570724e-01 1.026264e+00 3 5 TRUE FALSE 122 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5139075 0.4752422 0.4372640 U 0.4686274 0.6162291 13773 129 184016 184017 1 -3 Same + + 2.197225 0 2.197225 2.19722458 1.423054 3.100155 1.0850778 3842 ABC-type spermidine/putrescine transport systems, ATPase components E spermidine/putrescine transport ATP-binding protein 1.387247 3.531590 1.1708449 1176 ABC-type spermidine/putrescine transport system, permease component I E spermidine/putrescine transport permease protein 2.654237e-03 5 1.282182e-03 1.817808e-03 5.040198e-02 1.009018e-01 1.135116e-01 E 5 8 FALSE FALSE 123 TRUE 2.9321590 1.6745314 0.5480306 2.9469979 0.7448207 0.5079489 0.5188027 0.6022559 Y 1.4497162 0.8912321 13773 129 184017 184018 1 -3 Same + + 13.161584 0 15.464169 15.46416918 1.387247 3.531590 1.1708449 1176 ABC-type spermidine/putrescine transport system, permease component I E spermidine/putrescine transport permease protein 1.390117 3.323418 1.1061455 1177 ABC-type spermidine/putrescine transport system, permease component II E spermidine/putrescine transport permease protein 5.151514e-02 8 8.239465e-06 3.930596e-03 6.578106e-02 2.650192e-01 6.808775e-04 E 8 32 FALSE FALSE 124 TRUE 2.6120441 1.8821254 0.5480306 2.6658834 0.7652913 0.8479017 0.5755793 0.6526075 Y 1.4497162 0.9174032 13773 129 184018 184019 1 251 Convergent + - 0.000000 0 0.000000 0.00000000 1.390117 3.323418 1.1061455 1177 ABC-type spermidine/putrescine transport system, permease component II E spermidine/putrescine transport permease protein 1.526956 3.330181 1.1198169 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein, authentic frameshift 0.000000e+00 0 1.872491e-02 -4.630194e-03 -2.843482e-02 -3.320444e-01 1.353660e+00 0 32 0 FALSE FALSE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4318211 0.4222073 N 0.5492530 0.6245624 13773 129 184019 184020 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.526956 3.330181 1.1198169 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein, authentic frameshift 1.440283 3.282476 1.1112256 1651 Protein-disulfide isomerase O conserved within P. aerophilum 0.000000e+00 0 7.512209e-03 -8.394838e-04 -3.264482e-03 -5.077132e-03 4.478619e-01 0 0 0 TRUE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196517 0.5041686 N 0.5492530 0.6245624 13773 129 184020 184021 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.440283 3.282476 1.1112256 1651 Protein-disulfide isomerase O conserved within P. aerophilum 1.489787 3.110652 1.0028848 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 2.450581e-03 -4.265411e-04 1.918044e-02 -3.404388e-03 2.036413e-01 0 1 TRUE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198214 0.5784676 U 0.4686274 0.6162291 13773 129 184021 184022 1 21 Same - - 0.000000 0 0.000000 -0.07232066 1.489787 3.110652 1.0028848 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.369052 3.081574 1.0822005 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R conserved hypothetical protein 5.285113e-02 1 1.457683e-02 -3.161368e-03 -2.751422e-03 -2.961817e-01 1.234947e+00 1 2 TRUE FALSE 122 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.8555544 0.4414942 0.4269687 U 0.4686274 0.5573725 13773 129 184022 184023 1 0 Same - - 2.856470 0 5.519058 5.51905803 1.369052 3.081574 1.0822005 2425 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain R conserved hypothetical protein 1.332102 2.971837 1.0434763 714 MoxR-like ATPases R conserved hypothetical protein 9.844621e-02 2 1.365298e-03 9.822508e-03 1.545053e-01 5.769907e-01 3.860034e-02 2 3 TRUE FALSE 121 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 1.0091835 0.7111590 0.6286000 U 0.4686274 0.8613043 13773 129 184023 184024 1 154 Divergent - + 0.000000 0 0.000000 0.00000000 1.332102 2.971837 1.0434763 714 MoxR-like ATPases R conserved hypothetical protein 1.459837 3.257854 1.1135292 - - - hypothetical protein 0.000000e+00 0 1.631621e-02 -1.007307e-03 -2.699691e-02 -1.565170e-01 1.092611e+00 3 0 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4753708 0.4334958 U 0.4686274 0.6162291 13773 129 184024 184025 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.459837 3.257854 1.1135292 - - - hypothetical protein 1.424412 3.140747 1.1118213 433 Predicted ATPase R conserved hypothetical protein 0.000000e+00 0 1.254894e-03 -2.278256e-04 1.974142e-02 -3.224862e-02 1.290039e-01 0 7 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5115441 0.5983751 U 0.4686274 0.6162291 13773 129 184025 184026 1 -3 Same + + 2.590267 0 2.590267 2.57224866 1.424412 3.140747 1.1118213 433 Predicted ATPase R conserved hypothetical protein 1.429858 3.116473 1.0845816 420 DNA repair exonuclease L exonuclease sbcD, conjectural 4.283283e-02 3 2.964831e-05 5.810306e-04 2.686040e-02 2.118024e-02 3.492148e-03 7 3 FALSE FALSE 122 TRUE 2.9285866 1.6962575 0.5480306 2.9437919 0.7136133 0.8180840 0.5175729 0.6477695 U 0.4686274 0.8456551 13773 129 184026 184027 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.429858 3.116473 1.0845816 420 DNA repair exonuclease L exonuclease sbcD, conjectural 1.402503 3.074619 1.1011732 419 ATPase involved in DNA repair L purine NTPase, probable 0.000000e+00 0 7.482905e-04 1.052867e-03 3.794043e-02 4.683389e-02 7.548788e-02 L 3 0 FALSE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186732 0.6162896 Y 1.4497162 0.7118045 13773 129 184027 184028 1 3 Convergent + - 0.000000 0 0.000000 0.00000000 1.402503 3.074619 1.1011732 419 ATPase involved in DNA repair L purine NTPase, probable 1.336181 2.793850 0.9735827 1503 Peptide chain release factor 1 (eRF1) J peptide chain release factor aRF subunit 1 0.000000e+00 0 4.398622e-03 5.632757e-03 1.142365e-01 3.347868e-01 2.085187e-01 0 0 11 FALSE FALSE 124 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6067323 0.5767479 N 0.5492530 0.6245624 13773 129 184028 184029 1 79 Divergent - + 0.000000 0 0.000000 -1.10093594 1.336181 2.793850 0.9735827 1503 Peptide chain release factor 1 (eRF1) J peptide chain release factor aRF subunit 1 1.439074 3.240760 1.0994271 51 Ribosomal protein S10 J ribosomal protein S10 1.606241e-02 11 1.058711e-02 1.419260e-03 4.008297e-03 1.957817e-02 6.844610e-01 J 11 67 TRUE FALSE 123 FALSE 0.4469764 0.2074628 0.5480306 0.4469764 0.7764261 0.6483817 0.5176936 0.4662178 Y 1.4497162 0.6323429 13773 129 184029 184030 1 32 Same + + 2.197225 0 2.197225 -5.31061904 1.439074 3.240760 1.0994271 51 Ribosomal protein S10 J ribosomal protein S10 1.410878 3.226738 1.1161360 496 Predicted acid phosphatase R surE stationary-phase survival protein homolog 4.148562e-04 35 7.950443e-04 4.990920e-04 3.035640e-02 7.085603e-03 8.106978e-02 67 35 FALSE FALSE 124 TRUE 2.9321590 0.1818499 0.5480306 2.9469979 0.7746280 0.4539905 0.5192523 0.6140495 U 0.4686274 0.4429849 13773 129 184030 184031 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.410878 3.226738 1.1161360 496 Predicted acid phosphatase R surE stationary-phase survival protein homolog 1.436785 3.288570 1.1154269 - - - hypothetical protein 0.000000e+00 0 6.711952e-04 5.918350e-04 2.403094e-02 1.393502e-02 6.889114e-02 35 0 FALSE FALSE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182553 0.6181692 U 0.4686274 0.6162291 13773 129 184031 184032 1 -28 Convergent + - 0.000000 0 0.000000 0.00000000 1.436785 3.288570 1.1154269 - - - hypothetical protein 1.547601 3.499513 1.1277944 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 0.000000e+00 0 1.228009e-02 -1.405379e-03 2.726927e-02 -3.336064e-02 6.115888e-01 0 0 FALSE FALSE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5111485 0.4754795 U 0.4686274 0.6162291 13773 129 184032 184033 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.547601 3.499513 1.1277944 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein 1.459768 3.216440 1.0727610 1590 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 7.714569e-03 8.057588e-04 6.831427e-03 1.328771e-01 3.095902e-01 0 1 TRUE FALSE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5254116 0.5385067 U 0.4686274 0.6162291 13773 129 184033 184034 1 19 Same - - 0.000000 0 0.000000 -0.18221272 1.459768 3.216440 1.0727610 1590 Uncharacterized conserved protein S conserved hypothetical protein 1.393286 3.115313 1.0774654 329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase EM dihydrodipicolinate synthase 3.554731e-03 1 4.419865e-03 -4.866562e-04 2.344386e-02 -8.498600e-02 4.245478e-01 1 57 TRUE FALSE 124 TRUE 0.4469764 0.2749489 0.5480306 0.4469764 0.6329203 0.5281729 0.4967286 0.5079521 U 0.4686274 0.5492585 13773 129 184034 184035 1 80 Divergent - + 0.000000 0 0.000000 0.00000000 1.393286 3.115313 1.0774654 329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase EM dihydrodipicolinate synthase 1.682216 4.070810 1.1843317 - - - hypothetical protein 0.000000e+00 0 8.348071e-02 -1.341243e-02 -9.354955e-03 -4.520532e-01 2.046459e+00 57 0 TRUE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4117447 0.4077159 U 0.4686274 0.6162291 13773 129 184035 184036 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.682216 4.070810 1.1843317 - - - hypothetical protein 1.446718 3.116932 1.0913809 312 Predicted Zn-dependent proteases and their inactivated homologs R tldD, putative modulator of DNA gyrase 0.000000e+00 0 5.545954e-02 -1.079119e-03 -1.271278e-01 4.859204e-02 8.256853e-01 0 32 FALSE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187537 0.4524920 U 0.4686274 0.6162291 13773 129 184036 184037 1 -3 Same + + 10.604603 0 18.801489 18.16351238 1.446718 3.116932 1.0913809 312 Predicted Zn-dependent proteases and their inactivated homologs R tldD, putative modulator of DNA gyrase 1.444788 3.180642 1.1006746 312 Predicted Zn-dependent proteases and their inactivated homologs R pmbA, putative modulator of DNA gyrase 6.311121e-02 9 3.725602e-06 3.088018e-05 2.115404e-02 1.632692e-03 3.392608e-04 32 9 FALSE FALSE 125 TRUE 2.6607417 1.9027798 0.5480306 2.6109649 0.7702221 0.9015300 0.5198288 0.6537679 U 0.4686274 0.8805094 13773 129 184037 184038 1 134 Convergent + - 0.000000 0 0.000000 0.00000000 1.444788 3.180642 1.1006746 312 Predicted Zn-dependent proteases and their inactivated homologs R pmbA, putative modulator of DNA gyrase 1.371453 3.158600 0.9895597 - - - paREP10 0.000000e+00 0 5.377976e-03 5.280247e-04 4.302917e-02 -2.097762e-02 4.665425e-01 9 0 FALSE FALSE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5150132 0.5000023 U 0.4686274 0.6162291 13773 129 184038 184039 1 268 Same - - 0.000000 0 0.000000 0.00000000 1.371453 3.158600 0.9895597 - - - paREP10 1.495788 3.340149 1.1324082 - - - conserved within P. aerophilum 0.000000e+00 0 1.545925e-02 -3.548957e-03 -3.198096e-02 -3.116676e-01 1.276224e+00 0 0 TRUE FALSE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4372279 0.4252479 U 0.4686274 0.6162291 13773 129 184039 184040 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.495788 3.340149 1.1324082 - - - conserved within P. aerophilum 1.805149 3.913451 1.0885881 - - - hypothetical protein 0.000000e+00 0 9.570384e-02 1.570509e-02 5.171627e-01 4.748520e-01 2.628234e-01 0 0 TRUE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6644919 0.5561071 U 0.4686274 0.6162291 13773 129 184040 184041 1 149 Divergent - + 0.000000 0 0.000000 0.00000000 1.805149 3.913451 1.0885881 - - - hypothetical protein 1.451907 3.652962 1.1956527 477 Permeases of the major facilitator superfamily GEPR resistance protein, conjectural 0.000000e+00 0 1.247797e-01 1.817935e-04 -2.949380e-01 9.968848e-02 7.939179e-01 0 22 TRUE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186513 0.4559908 U 0.4686274 0.6162291 13773 129 184041 184042 1 -11 Convergent + - 0.000000 0 0.000000 -0.44206673 1.451907 3.652962 1.1956527 477 Permeases of the major facilitator superfamily GEPR resistance protein, conjectural 1.303350 2.774003 0.9709828 852 NADH:ubiquinone oxidoreductase 27 kD subunit C NADH-ubiquinone oxidoreductase subunit 9.712855e-03 11 2.206910e-02 -7.607857e-05 7.550510e-02 -9.428740e-02 1.078218e+00 22 11 FALSE FALSE 124 FALSE 0.4469764 0.2371052 0.5480306 0.4469764 0.7764261 0.5957827 0.4939051 0.4344863 U 0.4686274 0.5372951 13773 129 184042 184043 1 3 Same - - 2.512306 0 2.512306 2.45514721 1.303350 2.774003 0.9709828 852 NADH:ubiquinone oxidoreductase 27 kD subunit C NADH-ubiquinone oxidoreductase subunit 1.413580 3.100660 1.0461958 377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases C NADH-ubiquinone oxidoreductase subunit 6.552761e-03 7 1.215066e-02 5.597917e-03 3.416351e-02 2.583907e-01 4.386648e-01 C 11 7 TRUE FALSE 123 TRUE 2.9301853 1.6848950 0.5480306 2.9452541 0.7596462 0.5650491 0.5729220 0.5058537 Y 1.4497162 0.8925290 13773 129 184043 184044 1 97 Same - - 0.000000 0 0.000000 -0.24393432 1.413580 3.100660 1.0461958 377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases C NADH-ubiquinone oxidoreductase subunit 1.422267 3.119668 1.0542917 656 Aldo/keto reductases, related to diketogulonate reductase R aldo-keto reductase, putative 1.069412e-03 7 7.546543e-05 1.101326e-03 3.213798e-02 5.539964e-02 5.541848e-03 7 37 TRUE FALSE 122 TRUE 0.4469764 0.2667406 0.5480306 0.4469764 0.7596462 0.4722688 0.5187206 0.6460120 U 0.4686274 0.5466680 13773 129 184044 184045 1 458 Same - - 1.504077 0 4.512232 -2.63225122 1.422267 3.119668 1.0542917 656 Aldo/keto reductases, related to diketogulonate reductase R aldo-keto reductase, putative 1.644299 3.550234 1.0730074 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.009877e-01 37 4.929795e-02 -5.618520e-03 4.739184e-02 -1.868773e-01 1.277958e+00 37 44 TRUE FALSE 121 TRUE 2.9322497 0.1931314 0.5480306 2.9011386 0.7740003 1.0165791 0.4681846 0.4250355 U 0.4686274 0.4465317 13773 129 184045 184046 1 -3 Same - - 0.000000 0 0.000000 -0.05918887 1.644299 3.550234 1.0730074 1064 Zn-dependent alcohol dehydrogenases R alcohol dehydrogenase (Zinc) 1.538571 3.339879 1.0706312 3255 Putative sterol carrier protein I conserved hypothetical protein 5.865798e-03 3 1.117821e-02 1.681726e-02 1.421686e-01 6.583503e-01 4.885355e-02 44 3 TRUE FALSE 120 TRUE 0.4469764 0.3056289 0.5480306 0.4469764 0.7136133 0.5528145 0.7383057 0.6242586 U 0.4686274 0.5589164 13773 129 184046 184047 1 295 Same - - 0.000000 0 0.000000 0.00000000 1.538571 3.339879 1.0706312 3255 Putative sterol carrier protein I conserved hypothetical protein 1.354981 3.116537 1.0811941 - - - hypothetical protein 0.000000e+00 0 3.370535e-02 -8.405026e-03 -7.323159e-02 -5.316817e-01 2.128509e+00 3 0 TRUE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4005164 0.4069224 U 0.4686274 0.6162291 13773 129 184047 184048 1 57 Divergent - + 0.000000 0 0.000000 0.00000000 1.354981 3.116537 1.0811941 - - - hypothetical protein 1.391799 2.961679 1.0441961 1818 Predicted RNA-binding protein, contains THUMP domain R conserved hypothetical protein 0.000000e+00 0 1.355576e-03 5.745489e-03 7.332909e-02 3.646311e-01 7.010506e-02 0 0 TRUE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6172891 0.6177812 U 0.4686274 0.6162291 13773 129 184048 184049 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.391799 2.961679 1.0441961 1818 Predicted RNA-binding protein, contains THUMP domain R conserved hypothetical protein 1.369653 3.122999 1.0892480 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R conserved hypothetical protein 0.000000e+00 0 4.904824e-04 4.871176e-03 8.564174e-02 3.206368e-01 3.035029e-02 0 4 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5997525 0.6329638 U 0.4686274 0.6162291 13773 129 184049 184050 1 -17 Convergent + - 0.000000 0 0.000000 -0.40338394 1.369653 3.122999 1.0892480 596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) R conserved hypothetical protein 1.380155 2.990639 1.0509222 294 Dihydropteroate synthase and related enzymes H dihydropteroate synthase 2.651336e-03 4 1.102971e-04 5.823008e-03 8.474192e-02 3.834471e-01 6.248642e-03 4 48 FALSE FALSE 120 FALSE 0.4469764 0.2417643 0.5480306 0.4469764 0.7323301 0.5072982 0.6267563 0.6452751 U 0.4686274 0.5387705 13773 129 184050 184051 1 87 Divergent - + 0.000000 0 0.000000 0.00000000 1.380155 2.990639 1.0509222 294 Dihydropteroate synthase and related enzymes H dihydropteroate synthase 1.619779 3.406069 1.0721761 - - - hypothetical protein 0.000000e+00 0 5.741955e-02 -1.199546e-02 -6.039959e-02 -5.198830e-01 2.178059e+00 48 0 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4030241 0.4060318 U 0.4686274 0.6162291 13773 129 184051 184052 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.619779 3.406069 1.0721761 - - - hypothetical protein 1.415863 3.014596 1.0602228 621 2-methylthioadenine synthetase J conserved hypothetical protein 0.000000e+00 0 4.158151e-02 -5.982688e-03 -1.180125e-01 -2.286936e-01 1.323471e+00 0 58 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4573935 0.4233169 U 0.4686274 0.6162291 13773 129 184052 184053 1 109 Convergent + - 0.000000 0 0.000000 -12.44561265 1.415863 3.014596 1.0602228 621 2-methylthioadenine synthetase J conserved hypothetical protein 1.344753 2.830463 0.9963319 143 Methionyl-tRNA synthetase J methionyl-tRNA synthetase alpha subunit 3.957376e-04 58 5.056710e-03 3.788889e-03 9.071230e-02 2.071187e-01 3.078845e-01 J 58 66 FALSE FALSE 121 FALSE 0.4469764 0.1771744 0.5480306 0.4469764 0.7709797 0.4526705 0.5524530 0.5393143 Y 1.4497162 0.6233262 13773 129 184053 184054 1 23 Same - - 0.000000 0 0.000000 -0.41586382 1.344753 2.830463 0.9963319 143 Methionyl-tRNA synthetase J methionyl-tRNA synthetase alpha subunit 1.444740 3.357966 1.1418691 - - - conserved hypothetical protein 3.137307e-03 2 9.997570e-03 7.094076e-04 2.650360e-04 -2.487912e-02 7.075095e-01 66 2 TRUE FALSE 120 TRUE 0.4469764 0.2407184 0.5480306 0.4469764 0.6838149 0.5183257 0.5137976 0.4639635 U 0.4686274 0.5384394 13773 129 184054 184055 1 0 Same - - 0.000000 0 0.000000 -0.41586382 1.444740 3.357966 1.1418691 - - - conserved hypothetical protein 1.370909 2.942435 1.0188536 20 Undecaprenyl pyrophosphate synthase I conserved hypothetical protein 3.137307e-03 2 5.451116e-03 5.354077e-04 4.333557e-02 -2.014361e-02 4.717992e-01 2 66 TRUE FALSE 119 TRUE 0.4469764 0.2407184 0.5480306 0.4469764 0.6838149 0.5183257 0.5154929 0.4985726 U 0.4686274 0.5384394 13773 129 184055 184056 1 -22 Same - - 0.000000 0 0.000000 -0.89579163 1.370909 2.942435 1.0188536 20 Undecaprenyl pyrophosphate synthase I conserved hypothetical protein 1.401440 3.104437 1.0664649 73 EMAP domain R methionyl-tRNA synthetase beta subunit 1.313629e-02 8 9.321310e-04 4.020435e-03 5.763251e-02 2.653920e-01 6.336637e-02 66 8 TRUE FALSE 118 TRUE 0.4469764 0.2159734 0.5480306 0.4469764 0.7652913 0.6256402 0.5758045 0.6195004 U 0.4686274 0.5305951 13773 129 184056 184057 1 46 Divergent - + 0.000000 0 0.000000 0.00000000 1.401440 3.104437 1.0664649 73 EMAP domain R methionyl-tRNA synthetase beta subunit 1.554912 3.301215 1.0686863 - - - hypothetical protein 0.000000e+00 0 2.355376e-02 -5.171113e-03 -1.884738e-02 -3.082273e-01 1.360813e+00 8 0 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4379815 0.4217615 U 0.4686274 0.6162291 13773 129 184057 184058 1 141 Convergent + - 0.000000 0 0.000000 0.00000000 1.554912 3.301215 1.0686863 - - - hypothetical protein 1.413447 2.937350 0.9616685 - - - hypothetical protein 0.000000e+00 0 2.001226e-02 -3.928091e-03 -4.874803e-02 -2.128932e-01 1.084603e+00 0 0 FALSE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4608792 0.4341358 U 0.4686274 0.6162291 13773 129 184058 184059 1 6 Same - - 0.000000 0 0.000000 0.00000000 1.413447 2.937350 0.9616685 - - - hypothetical protein 1.459098 3.296581 1.1564411 - - - hypothetical protein 0.000000e+00 0 2.083992e-03 -2.923787e-04 1.381334e-02 -4.759546e-02 2.022583e-01 0 0 TRUE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5069804 0.5792906 U 0.4686274 0.6162291 13773 129 184059 184060 1 -34 Divergent - + 0.000000 0 0.000000 0.00000000 1.459098 3.296581 1.1564411 - - - hypothetical protein 1.375811 2.996996 1.0404782 1011 Predicted hydrolase (HAD superfamily) R conserved hypothetical protein 0.000000e+00 0 6.936800e-03 -5.823776e-04 2.828499e-02 -1.063052e-01 6.309455e-01 0 3 TRUE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4889630 0.4730477 U 0.4686274 0.6162291 13773 129 184060 184061 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.375811 2.996996 1.0404782 1011 Predicted hydrolase (HAD superfamily) R conserved hypothetical protein 1.475464 3.427662 1.1466969 455 ATPases involved in chromosome partitioning D hypothetical protein 0.000000e+00 0 9.930812e-03 -1.819357e-03 -1.357068e-02 -2.015969e-01 8.968948e-01 3 0 FALSE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4639547 0.4466307 U 0.4686274 0.6162291 13773 129 184061 184062 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.475464 3.427662 1.1466969 455 ATPases involved in chromosome partitioning D hypothetical protein 1.446215 3.351671 1.1225509 - - - hypothetical protein 0.000000e+00 0 8.554880e-04 -1.246289e-04 1.787712e-02 1.388613e-02 7.846878e-02 0 0 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182761 0.6152238 U 0.4686274 0.6162291 13773 129 184062 184063 1 41 Same - - 0.000000 0 0.000000 0.00000000 1.446215 3.351671 1.1225509 - - - hypothetical protein 1.540562 3.411667 1.0933600 - - - hypothetical protein 0.000000e+00 0 8.901311e-03 -4.616743e-04 3.546362e-02 3.080676e-02 4.540464e-01 0 0 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173943 0.5029866 U 0.4686274 0.6162291 13773 129 184063 184064 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.540562 3.411667 1.0933600 - - - hypothetical protein 1.422021 3.011554 1.0556592 - - - hypothetical protein 0.000000e+00 0 1.405194e-02 -2.619048e-03 -2.788616e-02 -1.474324e-01 8.509815e-01 0 0 TRUE FALSE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4776600 0.4503392 U 0.4686274 0.6162291 13773 129 184064 184065 1 301 Same + + 0.000000 0 0.000000 0.00000000 1.422021 3.011554 1.0556592 - - - hypothetical protein 1.397506 3.044862 1.0667490 834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain ET bacterial extracellular solute-binding proteins, family 3 0.000000e+00 0 6.009761e-04 1.582734e-03 4.442674e-02 9.155329e-02 5.733507e-02 0 15 FALSE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178651 0.6213153 U 0.4686274 0.6162291 13773 129 184065 184066 1 -15 Same + + 0.000000 0 0.000000 0.00000000 1.397506 3.044862 1.0667490 834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain ET bacterial extracellular solute-binding proteins, family 3 1.319822 3.086279 1.0415209 1430 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 6.034800e-03 7.089865e-03 1.402212e-01 3.993500e-01 2.043345e-01 15 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6345043 0.5782742 U 0.4686274 0.6162291 13773 129 184066 184067 1 549 Same + + 0.000000 0 0.000000 0.00000000 1.319822 3.086279 1.0415209 1430 Uncharacterized conserved protein S conserved hypothetical protein 1.343544 3.417032 1.1757412 - - - hypothetical protein 0.000000e+00 0 5.627018e-04 1.418975e-02 1.722255e-01 7.319121e-01 6.617941e-03 0 0 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7626112 0.6448898 U 0.4686274 0.6162291 13773 129 184067 184068 1 -39 Same + + 0.000000 0 0.000000 0.00000000 1.343544 3.417032 1.1757412 - - - hypothetical protein 1.401716 3.041203 1.0587861 846 NAD-dependent protein deacetylases, SIR2 family K conserved hypothetical protein 0.000000e+00 0 3.384020e-03 5.357595e-03 6.010903e-02 3.268247e-01 1.723875e-01 0 17 FALSE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6023599 0.5871112 U 0.4686274 0.6162291 13773 129 184068 184069 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.401716 3.041203 1.0587861 846 NAD-dependent protein deacetylases, SIR2 family K conserved hypothetical protein 1.428818 3.040000 1.0470165 1547 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 7.344891e-04 1.121468e-03 2.887751e-02 5.195991e-02 7.339400e-02 17 0 FALSE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187833 0.6168603 U 0.4686274 0.6162291 13773 129 184069 184070 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.428818 3.040000 1.0470165 1547 Uncharacterized conserved protein S conserved hypothetical protein 1.429222 3.073190 1.0781032 517 FOG: CBS domain R conserved protein with 2 CBS domains 0.000000e+00 0 1.633435e-07 5.005206e-04 2.654399e-02 1.622503e-02 2.120380e-05 0 9 TRUE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180551 0.6555893 U 0.4686274 0.6162291 13773 129 184070 184071 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.429222 3.073190 1.0781032 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.393036 3.132328 1.0814141 - - - hypothetical protein 0.000000e+00 0 1.309441e-03 1.293850e-03 4.326592e-02 5.913975e-02 1.208670e-01 9 0 TRUE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186029 0.6007310 U 0.4686274 0.6162291 13773 129 184071 184072 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.393036 3.132328 1.0814141 - - - hypothetical protein 1.459017 3.411522 1.1444407 - - - hypothetical protein 0.000000e+00 0 4.353561e-03 -4.449267e-04 7.034599e-03 -7.909488e-02 4.096786e-01 0 0 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4983209 0.5105099 U 0.4686274 0.6162291 13773 129 184072 184073 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.459017 3.411522 1.1444407 - - - hypothetical protein 1.388629 3.073390 1.1094301 - - - hypothetical protein 0.000000e+00 0 4.954500e-03 -4.785240e-04 2.499898e-02 -8.564332e-02 4.613151e-01 0 0 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4964384 0.5017230 U 0.4686274 0.6162291 13773 129 184073 184074 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.388629 3.073390 1.1094301 - - - hypothetical protein 1.371111 2.915413 1.0100036 - - - hypothetical protein 0.000000e+00 0 3.068648e-04 5.038797e-03 8.601624e-02 3.339304e-01 1.972483e-02 0 0 TRUE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6057974 0.6377141 U 0.4686274 0.6162291 13773 129 184074 184075 1 74 Divergent - + 0.000000 0 0.000000 0.00000000 1.371111 2.915413 1.0100036 - - - hypothetical protein 1.350468 2.958310 1.0301704 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase, putative 0.000000e+00 0 4.261517e-04 8.102422e-03 1.249731e-01 5.056517e-01 1.507826e-02 0 20 TRUE FALSE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6742724 0.6403514 U 0.4686274 0.6162291 13773 129 184075 184076 1 -10 Same + + 0.000000 0 0.000000 -1.13595021 1.350468 2.958310 1.0301704 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase, putative 1.399440 2.948491 1.0473882 8 Glutamyl- and glutaminyl-tRNA synthetases J glutamyl-tRNA synthetase 2.482542e-03 15 2.398264e-03 5.243354e-03 6.303178e-02 3.313506e-01 1.208670e-01 20 15 FALSE FALSE 114 TRUE 0.4469764 0.2059203 0.5480306 0.4469764 0.7783720 0.5053594 0.6044688 0.6007310 U 0.4686274 0.5274037 13773 129 184076 184077 1 -7 Same + + 0.000000 0 0.000000 -0.32561061 1.399440 2.948491 1.0473882 8 Glutamyl- and glutaminyl-tRNA synthetases J glutamyl-tRNA synthetase 1.506709 3.317769 1.1380589 1817 Uncharacterized protein conserved in archaea S conserved hypothetical protein 9.273304e-02 4 1.150659e-02 -2.873819e-03 -1.194774e-02 -2.345700e-01 9.529835e-01 15 4 FALSE FALSE 115 TRUE 0.4469764 0.2506458 0.5480306 0.4469764 0.7323301 0.9837346 0.4556806 0.4424150 U 0.4686274 0.5415813 13773 129 184077 184078 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.506709 3.317769 1.1380589 1817 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.404127 3.179855 1.0856347 - - - hypothetical protein 0.000000e+00 0 1.052304e-02 -2.614559e-03 -1.192949e-02 -2.050908e-01 8.509815e-01 4 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4629404 0.4503392 U 0.4686274 0.6162291 13773 129 184078 184079 1 -34 Convergent + - 0.000000 0 0.000000 0.00000000 1.404127 3.179855 1.0856347 - - - hypothetical protein 1.371930 2.992618 1.0268345 1936 Predicted nucleotide kinase (related to CMP and AMP kinases) F conserved hypothetical protein 0.000000e+00 0 1.036662e-03 3.755917e-03 7.501497e-02 2.406590e-01 7.297876e-02 0 8 FALSE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5654248 0.6169600 U 0.4686274 0.6162291 13773 129 184079 184080 1 -22 Same - - 0.000000 0 0.000000 -0.18221272 1.371930 2.992618 1.0268345 1936 Predicted nucleotide kinase (related to CMP and AMP kinases) F conserved hypothetical protein 1.394563 2.955129 1.0165458 17 Aspartyl/asparaginyl-tRNA synthetases J asparaginyl-tRNA synthetase 3.547665e-02 8 5.122594e-04 4.515911e-03 6.570524e-02 2.999589e-01 3.170203e-02 0 8 36 TRUE FALSE 116 TRUE 0.4469764 0.2749489 0.5480306 0.4469764 0.7652913 0.7770652 0.5918648 0.6317872 N 0.5492530 0.5580030 13773 129 184080 184081 1 4 Same - - 0.000000 0 0.000000 0.00000000 1.394563 2.955129 1.0165458 17 Aspartyl/asparaginyl-tRNA synthetases J asparaginyl-tRNA synthetase 1.385286 2.896041 0.9833989 - - - conserved hypothetical protein 0.000000e+00 0 8.604965e-05 3.756839e-03 6.755975e-02 2.559840e-01 6.997843e-03 36 0 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5724871 0.6444474 U 0.4686274 0.6162291 13773 129 184081 184082 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.385286 2.896041 0.9833989 - - - conserved hypothetical protein 1.461580 3.166711 1.0879953 2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases I 3-hydroxyisobutyrate dehydrogenase, putative 0.000000e+00 0 5.820714e-03 -6.734368e-04 2.029412e-03 -1.079603e-01 5.564725e-01 0 1 TRUE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4884996 0.4830103 U 0.4686274 0.6162291 13773 129 184082 184083 1 49 Divergent - + 0.000000 0 0.000000 -0.13353139 1.461580 3.166711 1.0879953 2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases I 3-hydroxyisobutyrate dehydrogenase, putative 1.500391 3.286882 1.1211025 9 Putative translation factor (SUA5) J sua5 family protein 1.102807e-02 1 1.506287e-03 4.991511e-04 3.240724e-02 1.002704e-01 9.852757e-02 0 1 33 TRUE FALSE 113 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.6060889 0.5187254 0.6071648 N 0.5492530 0.5604716 13773 129 184083 184084 1 -3 Same + + 0.000000 0 0.000000 -0.34265153 1.500391 3.286882 1.1211025 9 Putative translation factor (SUA5) J sua5 family protein 1.343799 2.919769 1.0025056 500 SAM-dependent methyltransferases QR methyltransferase 7.130277e-04 8 2.452102e-02 -5.271890e-03 -1.760116e-02 -4.155738e-01 1.754659e+00 33 8 FALSE FALSE 114 TRUE 0.4469764 0.2494684 0.5480306 0.4469764 0.7652913 0.4603858 0.4165336 0.4113510 U 0.4686274 0.5412088 13773 129 184084 184085 1 25 Same + + 0.000000 0 0.000000 -1.63396634 1.343799 2.919769 1.0025056 500 SAM-dependent methyltransferases QR methyltransferase 1.467067 3.232993 1.0780114 462 Phosphoribosylpyrophosphate synthetase FE ribose-phosphate pyrophosphokinase 6.541102e-04 8 1.519507e-02 -1.686475e-03 -2.775556e-02 -1.968508e-01 1.115188e+00 8 62 FALSE FALSE 115 TRUE 0.4469764 0.2001585 0.5480306 0.4469764 0.7652913 0.4599161 0.4651009 0.4320538 U 0.4686274 0.5255735 13773 129 184085 184086 1 -5 Convergent + - 0.000000 0 0.000000 -1.86225522 1.467067 3.232993 1.0780114 462 Phosphoribosylpyrophosphate synthetase FE ribose-phosphate pyrophosphokinase 1.429568 3.005984 1.0488099 123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein BQ acetylpolyamine aminohydrolase, putative 6.363500e-02 22 1.406170e-03 -3.420869e-04 1.732357e-02 -2.949978e-02 1.323329e-01 62 22 FALSE FALSE 116 FALSE 0.4469764 0.1980216 0.5480306 0.4469764 0.7773546 0.9031642 0.5123360 0.5978214 U 0.4686274 0.5248946 13773 129 184086 184087 1 60 Divergent - + 0.000000 0 0.000000 0.00000000 1.429568 3.005984 1.0488099 123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein BQ acetylpolyamine aminohydrolase, putative 1.305496 2.719957 0.9952022 - - - hypothetical protein 0.000000e+00 0 1.539392e-02 3.184120e-03 1.108133e-01 1.135039e-01 6.530823e-01 22 0 TRUE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5205246 0.4700463 U 0.4686274 0.6162291 13773 129 184087 184088 1 -22 Convergent + - 0.000000 0 0.000000 0.00000000 1.305496 2.719957 0.9952022 - - - hypothetical protein 1.551535 3.386696 1.0422159 1402 Uncharacterized protein, putative amidase R conserved hypothetical protein 0.000000e+00 0 6.053508e-02 -1.461040e-02 -1.786795e-01 -6.938731e-01 2.809418e+00 0 15 FALSE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3881839 0.4018000 U 0.4686274 0.6162291 13773 129 184088 184089 1 87 Divergent - + 0.000000 0 0.000000 -0.15725008 1.551535 3.386696 1.0422159 1402 Uncharacterized protein, putative amidase R conserved hypothetical protein 1.522682 3.315424 1.0938136 2429 Uncharacterized conserved protein S conserved hypothetical protein 1.970976e-02 6 8.325102e-04 7.139012e-03 9.164775e-02 4.734596e-01 1.238361e-02 15 6 TRUE FALSE 115 FALSE 0.4469764 0.2762022 0.5480306 0.4469764 0.7537284 0.6758331 0.6641493 0.6418162 U 0.4686274 0.5496538 13773 129 184089 184090 1 -3 Same + + 0.000000 0 0.000000 -0.27039274 1.522682 3.315424 1.0938136 2429 Uncharacterized conserved protein S conserved hypothetical protein 1.423484 3.120426 1.0611501 1985 Pyrimidine reductase, riboflavin biosynthesis H riboflavin specific deaminase, putative 1.020864e-01 6 9.840179e-03 -1.989589e-03 -1.345314e-02 -1.198262e-01 6.781263e-01 6 12 FALSE FALSE 116 TRUE 0.4469764 0.2585977 0.5480306 0.4469764 0.7537284 1.0221623 0.4852188 0.4669420 U 0.4686274 0.5440956 13773 129 184090 184091 1 8 Same + + 0.000000 0 0.000000 -0.65114082 1.423484 3.120426 1.0611501 1985 Pyrimidine reductase, riboflavin biosynthesis H riboflavin specific deaminase, putative 1.459406 3.147446 1.0773533 108 3,4-dihydroxy-2-butanone 4-phosphate synthase H GTP cyclohydrolase II 1.854570e-01 12 1.290366e-03 -2.236284e-04 1.630798e-02 -3.332530e-02 1.334520e-01 H 12 13 FALSE FALSE 117 TRUE 0.4469764 0.2273367 0.5480306 0.4469764 0.7776747 1.1219429 0.5112145 0.5974546 Y 1.4497162 0.6382099 13773 129 184091 184092 1 -16 Convergent + - 0.000000 0 0.000000 -0.11778304 1.459406 3.147446 1.0773533 108 3,4-dihydroxy-2-butanone 4-phosphate synthase H GTP cyclohydrolase II 1.369555 2.799328 0.9277650 727 Predicted Fe-S-cluster oxidoreductase R conserved hypothetical protein 7.654975e-03 2 8.073174e-03 -6.557530e-04 2.991566e-02 -1.166386e-01 7.010688e-01 13 2 FALSE FALSE 118 FALSE 0.4469764 0.2945188 0.5480306 0.4469764 0.6838149 0.5743751 0.4860455 0.4647282 U 0.4686274 0.5554237 13773 129 184092 184093 1 53 Divergent - + 0.000000 0 0.000000 0.00000000 1.369555 2.799328 0.9277650 727 Predicted Fe-S-cluster oxidoreductase R conserved hypothetical protein 1.519910 3.311792 1.1181128 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 1.523153e-03 2 2.260662e-02 -5.607291e-03 -4.991069e-02 -4.092492e-01 1.638714e+00 2 4 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.4836464 0.4176076 0.4137816 U 0.4686274 0.6162291 13773 129 184093 184094 1 -5 Convergent + - 0.000000 0 0.000000 -0.20450080 1.519910 3.311792 1.1181128 644 Dehydrogenases (flavoproteins) C conserved hypothetical protein 1.422487 3.109467 1.0708789 1488 Nicotinic acid phosphoribosyltransferase H conserved hypothetical protein 5.109106e-02 4 9.491113e-03 -1.980510e-03 -1.221908e-02 -1.231075e-01 6.693073e-01 0 4 30 FALSE FALSE 118 FALSE 0.4469764 0.2717439 0.5480306 0.4469764 0.7323301 0.8433483 0.4841488 0.4688853 N 0.5492530 0.5569956 13773 129 184094 184095 1 32 Divergent - + 0.000000 0 0.000000 -1.04300948 1.422487 3.109467 1.0708789 1488 Nicotinic acid phosphoribosyltransferase H conserved hypothetical protein 1.461813 3.153437 1.0982007 1199 Rad3-related DNA helicases KL conserved hypothetical protein 7.695582e-03 13 1.546525e-03 -3.012082e-04 1.536982e-02 -3.981543e-02 1.592641e-01 30 13 TRUE FALSE 117 FALSE 0.4469764 0.2089931 0.5480306 0.4469764 0.7781369 0.5761033 0.5091592 0.5901897 U 0.4686274 0.5283794 13773 129 184095 184096 1 -28 Convergent + - 0.000000 0 0.000000 0.00000000 1.461813 3.153437 1.0982007 1199 Rad3-related DNA helicases KL conserved hypothetical protein 1.496163 3.483385 1.0964711 - - - hypothetical protein 0.000000e+00 0 1.179910e-03 4.665281e-04 3.100685e-02 9.623344e-02 7.846878e-02 13 0 FALSE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181220 0.6152238 U 0.4686274 0.6162291 13773 129 184096 184097 1 71 Divergent - + 0.000000 0 0.000000 0.00000000 1.496163 3.483385 1.0964711 - - - hypothetical protein 1.437054 3.154488 1.1023910 550 Topoisomerase IA L DNA topoisomerase (topA) 0.000000e+00 0 3.493921e-03 -6.419656e-04 8.663654e-03 -2.138521e-02 2.755646e-01 0 12 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5148769 0.5521597 U 0.4686274 0.6162291 13773 129 184097 184098 1 -7 Same + + 0.000000 0 0.000000 -0.25208038 1.437054 3.154488 1.1023910 550 Topoisomerase IA L DNA topoisomerase (topA) 1.444984 3.111572 1.0584211 1736 Diphthamide synthase subunit DPH2 J conserved hypothetical protein 3.671477e-02 5 6.288137e-05 9.190379e-05 2.139443e-02 -1.537275e-03 6.248642e-03 0 12 5 FALSE FALSE 118 TRUE 0.4469764 0.2632714 0.5480306 0.4469764 0.7448207 0.7825692 0.5199781 0.6452751 N 0.5492530 0.5543303 13773 129 184098 184099 1 7 Same + + 0.000000 0 0.000000 0.00000000 1.444984 3.111572 1.0584211 1736 Diphthamide synthase subunit DPH2 J conserved hypothetical protein 1.394883 2.910434 1.0198843 - - - hypothetical protein 0.000000e+00 0 2.510086e-03 3.621910e-04 3.297785e-02 -1.606188e-02 2.496164e-01 5 0 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5168205 0.5628925 U 0.4686274 0.6162291 13773 129 184099 184100 1 40 Same + + 0.000000 0 0.000000 0.00000000 1.394883 2.910434 1.0198843 - - - hypothetical protein 1.438378 3.145068 1.0972168 433 Predicted ATPase R conserved hypothetical protein 0.000000e+00 0 1.891876e-03 7.354437e-04 2.165719e-02 1.499109e-02 1.873568e-01 0 2 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181535 0.5834990 U 0.4686274 0.6162291 13773 129 184100 184101 1 10 Convergent + - 0.000000 0 0.000000 -0.13294528 1.438378 3.145068 1.0972168 433 Predicted ATPase R conserved hypothetical protein 1.387261 2.961162 1.0291804 5256 Translation elongation factor EF-1alpha (GTPase) J translation elongation factor aEF-1 alpha subunit 3.982039e-03 2 2.613026e-03 8.346403e-04 4.051124e-02 1.697011e-02 2.442772e-01 2 64 FALSE FALSE 121 FALSE 0.4469764 0.2864925 0.5480306 0.4469764 0.6838149 0.5358589 0.5179792 0.5648306 U 0.4686274 0.5528971 13773 129 184101 184102 1 116 Same - - 0.000000 0 0.000000 -6.82012478 1.387261 2.961162 1.0291804 5256 Translation elongation factor EF-1alpha (GTPase) J translation elongation factor aEF-1 alpha subunit 1.328587 2.859543 0.9973405 1335 Amidases related to nicotinamidase Q isochorismatase, putative -5.209427e-02 34 3.442579e-03 7.875790e-03 1.406777e-01 4.585969e-01 1.187419e-01 0 64 34 TRUE FALSE 120 TRUE 0.4469764 0.1806899 0.5480306 0.4469764 0.7748967 0.5246260 0.6600740 0.6011648 N 0.5492530 0.5282110 13773 129 184102 184103 1 328 Divergent - + 0.000000 0 0.000000 0.00000000 1.328587 2.859543 0.9973405 1335 Amidases related to nicotinamidase Q isochorismatase, putative 1.661157 3.535835 1.1271021 - - - paREP2a 0.000000e+00 0 1.106028e-01 -2.576024e-02 -2.070161e-01 -8.189231e-01 3.280463e+00 34 0 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3815301 0.4000911 U 0.4686274 0.6162291 13773 129 184103 184104 1 79 Same + + 0.000000 0 0.000000 0.00000000 1.661157 3.535835 1.1271021 - - - paREP2a 1.362811 2.895437 0.9812094 251 Putative translation initiation inhibitor, yjgF family J conserved hypothetical protein 0.000000e+00 0 8.901018e-02 -1.858122e-02 -2.883336e-01 -6.659612e-01 2.717564e+00 0 50 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3895986 0.4022795 U 0.4686274 0.6162291 13773 129 184104 184105 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.362811 2.895437 0.9812094 251 Putative translation initiation inhibitor, yjgF family J conserved hypothetical protein 1.480643 3.202945 1.0609089 - - - hypothetical protein 0.000000e+00 0 1.388440e-02 -2.591063e-03 -2.731164e-02 -2.620354e-01 1.162690e+00 50 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4495190 0.4300663 U 0.4686274 0.6162291 13773 129 184105 184106 1 39 Same + + 0.000000 0 0.000000 0.00000000 1.480643 3.202945 1.0609089 - - - hypothetical protein 1.360455 3.043622 1.0779861 - - - hypothetical protein 0.000000e+00 0 1.444520e-02 -2.659980e-03 8.464473e-03 -2.662938e-01 1.187648e+00 0 0 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4483405 0.4288368 U 0.4686274 0.6162291 13773 129 184106 184107 1 181 Convergent + - 0.000000 0 0.000000 0.00000000 1.360455 3.043622 1.0779861 - - - hypothetical protein 1.670595 3.775329 1.1117028 - - - paREP2a 0.000000e+00 0 9.618683e-02 -1.993374e-02 -1.113112e-01 -6.845187e-01 2.791438e+00 0 0 FALSE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3886560 0.4019369 U 0.4686274 0.6162291 13773 129 184107 184108 1 7 Same - - 0.000000 0 0.000000 0.00000000 1.670595 3.775329 1.1117028 - - - paREP2a 1.527957 3.216978 1.0369013 - - - paREP2a 0.000000e+00 0 2.034567e-02 1.678307e-02 1.098341e-01 6.334352e-01 8.106978e-02 0 0 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7314575 0.6140495 U 0.4686274 0.6162291 13773 129 184108 184109 1 10 Divergent - + 0.000000 0 0.000000 0.00000000 1.527957 3.216978 1.0369013 - - - paREP2a 1.426245 3.006360 1.0296258 - - - paREP2b 0.000000e+00 0 1.034529e-02 -1.925406e-03 -1.505551e-02 -1.063394e-01 6.819236e-01 0 0 TRUE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4888472 0.4666119 U 0.4686274 0.6162291 13773 129 184109 184110 1 399 Same + + 0.000000 0 0.000000 0.00000000 1.426245 3.006360 1.0296258 - - - paREP2b 1.520386 3.360320 1.1112507 - - - conserved within P. aerophilum 0.000000e+00 0 8.862498e-03 -1.735014e-03 1.093367e-02 -9.972382e-02 6.151952e-01 0 0 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4912631 0.4752630 U 0.4686274 0.6162291 13773 129 184110 184111 1 13 Convergent + - 0.000000 0 0.000000 0.00000000 1.520386 3.360320 1.1112507 - - - conserved within P. aerophilum 1.392119 3.017324 1.0402515 1720 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.645234e-02 -4.089467e-03 -3.024359e-02 -3.015687e-01 1.226433e+00 0 4 FALSE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4400289 0.4274593 U 0.4686274 0.6162291 13773 129 184111 184112 1 126 Same - - 0.000000 0 0.000000 0.00000000 1.392119 3.017324 1.0402515 1720 Uncharacterized conserved protein S conserved hypothetical protein 1.428500 3.155809 1.0596087 - - - hypothetical protein 0.000000e+00 0 1.323533e-03 1.356950e-03 2.901230e-02 6.520404e-02 1.208670e-01 4 0 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182685 0.6007310 U 0.4686274 0.6162291 13773 129 184112 184113 1 326 Same - - 0.000000 0 0.000000 0.00000000 1.428500 3.155809 1.0596087 - - - hypothetical protein 1.489763 3.303768 1.0601337 - - - conserved within P. aerophilum 0.000000e+00 0 3.753190e-03 -8.784115e-04 1.287498e-02 -5.981356e-02 3.339651e-01 0 0 TRUE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5037176 0.5300523 U 0.4686274 0.6162291 13773 129 184113 184114 1 -28 Same - - 0.000000 0 0.000000 0.00000000 1.489763 3.303768 1.0601337 - - - conserved within P. aerophilum 1.559038 3.738425 1.2021764 - - - hypothetical protein 0.000000e+00 0 4.799012e-03 4.130370e-03 9.471877e-02 3.415490e-01 1.078944e-01 0 0 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6090195 0.6036927 U 0.4686274 0.6162291 13773 129 184114 184115 1 181 Same - - 0.000000 0 0.000000 0.00000000 1.559038 3.738425 1.2021764 - - - hypothetical protein 1.438281 3.454605 1.1237616 - - - hypothetical protein 0.000000e+00 0 1.458229e-02 -1.411444e-03 -2.475520e-02 -2.604533e-02 6.481300e-01 0 0 TRUE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5134636 0.4705979 U 0.4686274 0.6162291 13773 129 184115 184116 1 81 Same - - 0.000000 0 0.000000 0.00000000 1.438281 3.454605 1.1237616 - - - hypothetical protein 1.478805 3.354787 1.0680063 - - - hypothetical protein 0.000000e+00 0 1.642199e-03 -3.594270e-04 1.800680e-02 -1.202491e-02 1.519983e-01 0 0 TRUE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179220 0.5926706 U 0.4686274 0.6162291 13773 129 184116 184117 1 409 Same - - 0.000000 0 0.000000 0.00000000 1.478805 3.354787 1.0680063 - - - hypothetical protein 1.368108 2.963392 1.0870720 - - - hypothetical protein 0.000000e+00 0 1.225390e-02 -2.283021e-03 9.750880e-03 -2.410448e-01 1.067091e+00 0 0 TRUE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4534556 0.4350139 U 0.4686274 0.6162291 13773 129 184117 184118 1 817 Divergent - + 0.000000 0 0.000000 0.00000000 1.368108 2.963392 1.0870720 - - - hypothetical protein 1.406515 3.148186 1.0829615 388 Predicted amidohydrolase R carbon nitrogen hydrolase, conjectural 0.000000e+00 0 1.475124e-03 3.737671e-03 5.193909e-02 2.342914e-01 1.094122e-01 0 3 TRUE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5634606 0.6033049 U 0.4686274 0.6162291 13773 129 184118 184119 1 280 Convergent + - 0.000000 0 0.000000 0.00000000 1.406515 3.148186 1.0829615 388 Predicted amidohydrolase R carbon nitrogen hydrolase, conjectural 1.365381 2.954404 1.0241136 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase 1.713491e-03 3 1.691972e-03 3.860019e-03 7.954272e-02 2.398697e-01 1.203339e-01 3 3 FALSE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.4893941 0.5644366 0.6009275 U 0.4686274 0.6162291 13773 129 184119 184120 1 2 Same - - 4.935912 0 7.598500 7.59849957 1.365381 2.954404 1.0241136 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ sugar-phosphate nucleotidyl transferase 1.369081 2.960348 1.0554106 449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains M glucosamine--fructose-6-phosphate aminotransferase (isomerizing) 6.672049e-03 3 1.369083e-05 7.079730e-03 1.019342e-01 4.621880e-01 6.808775e-04 3 63 TRUE FALSE 116 TRUE 2.8363652 1.8151775 0.5480306 2.8096798 0.7136133 0.5663031 0.6610867 0.6526075 U 0.4686274 0.8657478 13773 129 184120 184121 1 61 Same - - 0.000000 0 0.000000 0.00000000 1.369081 2.960348 1.0554106 449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains M glucosamine--fructose-6-phosphate aminotransferase (isomerizing) 1.371731 2.999263 1.0544452 618 Exopolyphosphatase-related proteins R conserved hypothetical protein 0.000000e+00 0 7.018223e-06 6.557109e-03 9.631555e-02 4.325015e-01 3.392608e-04 63 0 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6488752 0.6537679 U 0.4686274 0.6162291 13773 129 184121 184122 1 116 Divergent - + 0.000000 0 0.000000 0.00000000 1.371731 2.999263 1.0544452 618 Exopolyphosphatase-related proteins R conserved hypothetical protein 1.347561 2.986227 1.0480501 - - - hypothetical protein 0.000000e+00 0 5.841510e-04 8.271442e-03 1.287122e-01 5.151198e-01 2.126270e-02 0 0 TRUE FALSE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6803976 0.6369786 U 0.4686274 0.6162291 13773 129 184122 184123 1 273 Same + + 0.000000 0 0.000000 0.00000000 1.347561 2.986227 1.0480501 - - - hypothetical protein 1.407019 3.335956 1.1694700 1287 Uncharacterized membrane protein, required for N-linked glycosylation R oligosaccharyl transferase STT3 homolog 0.000000e+00 0 3.535259e-03 4.607352e-03 5.223007e-02 2.694473e-01 2.071193e-01 0 0 FALSE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5792539 0.5774877 U 0.4686274 0.6162291 13773 129 184123 184124 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.407019 3.335956 1.1694700 1287 Uncharacterized membrane protein, required for N-linked glycosylation R oligosaccharyl transferase STT3 homolog 1.432519 3.248675 1.0952041 2260 Predicted Zn-ribbon RNA-binding protein J conserved hypothetical protein 0.000000e+00 0 6.502158e-04 8.375058e-04 2.643441e-02 2.811624e-02 6.570586e-02 0 3 FALSE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173816 0.6189031 U 0.4686274 0.6162291 13773 129 184124 184125 1 -3 Same - - 7.483119 0 10.276327 10.27632743 1.432519 3.248675 1.0952041 2260 Predicted Zn-ribbon RNA-binding protein J conserved hypothetical protein 1.445281 3.073692 1.0282537 1093 Translation initiation factor 2, alpha subunit (eIF-2alpha) J translation initiation factor aIF-2 alpha subunit 7.846874e-02 3 1.628835e-04 1.153483e-04 2.127658e-02 -2.989736e-03 1.415059e-02 J 3 12 TRUE FALSE 115 TRUE 2.7337662 1.8433533 0.5480306 2.7524417 0.7136133 0.9433797 0.5198478 0.6408729 Y 1.4497162 0.9123830 13773 129 184125 184126 1 41 Same - - 18.655523 0 23.515335 23.19732121 1.445281 3.073692 1.0282537 1093 Translation initiation factor 2, alpha subunit (eIF-2alpha) J translation initiation factor aIF-2 alpha subunit 1.409821 3.130552 1.0789084 2051 Ribosomal protein S27E J ribosomal protein S27 4.432379e-01 12 1.257461e-03 2.540673e-04 2.800236e-02 -1.137760e-02 1.235498e-01 J 12 12 TRUE FALSE 114 TRUE 2.4331275 1.9361847 0.5480306 2.5333655 0.7776747 1.2514686 0.5181949 0.5998031 Y 1.4497162 0.9240461 13773 129 184126 184127 1 2 Same - - 20.611775 0 28.880981 28.88098112 1.409821 3.130552 1.0789084 2051 Ribosomal protein S27E J ribosomal protein S27 1.546033 3.286474 1.0371540 1631 Ribosomal protein L44E J ribosomal protein L44 2.393230e-01 8 1.855370e-02 -3.934382e-03 -6.907505e-03 -2.309412e-01 1.097429e+00 J 12 8 TRUE FALSE 113 TRUE 2.3451306 1.9572874 0.5480306 2.4725492 0.7652913 1.1721472 0.4567741 0.4330324 Y 1.4497162 0.9266568 13773 129 184127 184128 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.546033 3.286474 1.0371540 1631 Ribosomal protein L44E J ribosomal protein L44 1.342831 3.031311 1.0214410 - - - hypothetical protein 0.000000e+00 0 4.129087e-02 -1.027426e-02 -9.220768e-02 -5.995480e-01 2.405713e+00 8 0 TRUE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3942818 0.4040016 U 0.4686274 0.6162291 13773 129 184128 184129 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.342831 3.031311 1.0214410 - - - hypothetical protein 1.418383 2.944863 1.0077014 1467 Eukaryotic-type DNA primase, catalytic (small) subunit L DNA primase related protein 0.000000e+00 0 5.708143e-03 3.583569e-03 3.547513e-02 1.910509e-01 3.428943e-01 0 8 TRUE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5464741 0.5266146 U 0.4686274 0.6162291 13773 129 184129 184130 1 -3 Same - - 2.079442 0 2.079442 1.49418465 1.418383 2.944863 1.0077014 1467 Eukaryotic-type DNA primase, catalytic (small) subunit L DNA primase related protein 1.305768 2.868950 0.9986898 592 DNA polymerase sliding clamp subunit (PCNA homolog) L proliferating-cell nuclear antigen homolog (PCNA) 2.393230e-01 8 1.268220e-02 4.807000e-03 1.280296e-01 2.168348e-01 4.845357e-01 L 8 12 TRUE FALSE 110 TRUE 2.9335626 1.6418870 0.5480306 2.9479804 0.7652913 1.1721472 0.5560661 0.4953921 Y 1.4497162 0.8871167 13773 129 184130 184131 1 103 Same - - 10.700995 0 18.504838 18.08545746 1.305768 2.868950 0.9986898 592 DNA polymerase sliding clamp subunit (PCNA homolog) L proliferating-cell nuclear antigen homolog (PCNA) 1.544162 3.203826 1.0325313 1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS K DNA-directed RNA polymerase subunit M 3.229691e-01 10 5.683149e-02 -1.350944e-02 -1.692175e-01 -6.754688e-01 2.742926e+00 0 12 10 TRUE FALSE 109 TRUE 2.6513462 1.8986352 0.5480306 2.6161757 0.7739415 1.2322996 0.3893631 0.4021424 N 0.5492530 0.8837605 13773 129 184131 184132 1 102 Divergent - + 0.000000 0 0.000000 -0.97828712 1.544162 3.203826 1.0325313 1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS K DNA-directed RNA polymerase subunit M 1.382233 3.059724 1.0497597 2238 Ribosomal protein S19E (S16A) J ribosomal protein S19 3.229691e-01 10 2.622104e-02 -6.415920e-03 -6.398734e-02 -4.127555e-01 1.676260e+00 0 10 12 TRUE FALSE 108 FALSE 0.4469764 0.2115163 0.5480306 0.4469764 0.7739415 1.2322996 0.4169638 0.4127699 N 0.5492530 0.5379868 13773 129 184132 184133 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.382233 3.059724 1.0497597 2238 Ribosomal protein S19E (S16A) J ribosomal protein S19 1.419967 3.120064 1.0706143 2118 DNA-binding protein R conserved hypothetical protein 0.000000e+00 0 1.423882e-03 2.173429e-03 3.651118e-02 1.246548e-01 1.214012e-01 12 0 FALSE FALSE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5229927 0.6004968 U 0.4686274 0.6162291 13773 129 184133 184134 1 38 Same + + 0.000000 0 0.000000 0.00000000 1.419967 3.120064 1.0706143 2118 DNA-binding protein R conserved hypothetical protein 1.387023 3.264630 1.2288216 - - - ribosomal protein L39E, frameshift 0.000000e+00 0 1.085317e-03 2.022892e-03 5.240440e-02 1.165691e-01 9.708748e-02 0 0 FALSE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5214315 0.6079718 U 0.4686274 0.6162291 13773 129 184134 184135 1 91 Convergent + - 0.000000 0 0.000000 0.00000000 1.387023 3.264630 1.2288216 - - - ribosomal protein L39E, frameshift 1.445454 3.216169 1.0700985 1646 Predicted phosphate-binding enzymes, TIM-barrel fold R pcrB homolog 0.000000e+00 0 3.414237e-03 3.822698e-04 1.477438e-02 -1.997162e-02 3.234056e-01 0 15 FALSE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5155618 0.5336048 U 0.4686274 0.6162291 13773 129 184135 184136 1 -13 Same - - 0.000000 0 0.000000 0.00000000 1.445454 3.216169 1.0700985 1646 Predicted phosphate-binding enzymes, TIM-barrel fold R pcrB homolog 1.413268 2.881542 0.9900556 4888 Uncharacterized Zn ribbon-containing protein R conserved hypothetical protein 0.000000e+00 0 1.035969e-03 2.264106e-04 2.698662e-02 -1.062075e-02 1.024196e-01 15 0 TRUE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183479 0.6055846 U 0.4686274 0.6162291 13773 129 184136 184137 1 130 Divergent - + 0.000000 0 0.000000 0.00000000 1.413268 2.881542 0.9900556 4888 Uncharacterized Zn ribbon-containing protein R conserved hypothetical protein 1.435251 3.087688 1.0764464 303 Molybdopterin biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 0.000000e+00 0 4.832572e-04 6.154146e-04 2.490376e-02 1.712325e-02 4.919340e-02 0 1 TRUE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179063 0.6240491 U 0.4686274 0.6162291 13773 129 184137 184138 1 -20 Convergent + - 0.000000 0 0.000000 0.00000000 1.435251 3.087688 1.0764464 303 Molybdopterin biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 1.403741 2.976841 1.0238262 2236 Predicted phosphoribosyltransferases R phosphoribosyl transferase 9.520652e-04 1 9.928566e-04 7.691914e-04 3.483599e-02 2.298610e-02 1.014396e-01 1 5 FALSE FALSE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.5174697 0.6061495 U 0.4686274 0.6162291 13773 129 184138 184139 1 42 Same - - 0.000000 0 0.000000 0.00000000 1.403741 2.976841 1.0238262 2236 Predicted phosphoribosyltransferases R phosphoribosyl transferase 1.443845 3.282502 1.1256136 - - - hypothetical protein 0.000000e+00 0 1.608304e-03 3.596719e-04 1.932135e-02 -9.310824e-03 1.629606e-01 5 0 TRUE FALSE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187601 0.5893580 U 0.4686274 0.6162291 13773 129 184139 184140 1 94 Same - - 0.000000 0 0.000000 0.00000000 1.443845 3.282502 1.1256136 - - - hypothetical protein 1.497065 3.258989 1.1037526 - - - hypothetical protein 0.000000e+00 0 2.832334e-03 -3.447279e-04 2.185954e-02 1.189298e-02 2.113318e-01 0 0 TRUE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186611 0.5758379 U 0.4686274 0.6162291 13773 129 184140 184141 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.497065 3.258989 1.1037526 - - - hypothetical protein 1.459599 3.231775 1.1308883 483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family G extragenic suppressor protein suhB homolog 0.000000e+00 0 1.403656e-03 3.747973e-04 1.999377e-02 8.659572e-02 9.329907e-02 0 22 TRUE FALSE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176919 0.6097348 U 0.4686274 0.6162291 13773 129 184141 184142 1 124 Same - - 0.000000 0 0.000000 0.00000000 1.459599 3.231775 1.1308883 483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family G extragenic suppressor protein suhB homolog 1.465602 3.138234 1.0712956 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 0.000000e+00 0 3.603267e-05 1.166042e-04 2.244276e-02 4.021006e-02 2.120380e-03 0 22 0 TRUE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182150 0.6501030 N 0.5492530 0.6245624 13773 129 184142 184143 1 140 Same - - 0.000000 0 0.000000 0.00000000 1.465602 3.138234 1.0712956 467 RecA-superfamily ATPases implicated in signal transduction T P. aerophilum family 417, putative ATP binding 1.789632 3.691430 1.1360227 3269 Predicted RNA-binding protein, contains TRAM domain R conserved hypothetical protein 0.000000e+00 0 1.049956e-01 4.806059e-03 3.669533e-01 2.224496e-01 5.842919e-01 0 0 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5582106 0.4791334 U 0.4686274 0.6162291 13773 129 184143 184144 1 1279 Same - - 0.000000 0 0.000000 0.00000000 1.789632 3.691430 1.1360227 3269 Predicted RNA-binding protein, contains TRAM domain R conserved hypothetical protein 1.605426 3.545064 1.0923047 - - - hypothetical protein 0.000000e+00 0 3.393185e-02 5.210010e-02 3.996251e-01 8.655037e-01 1.307626e-02 0 0 TRUE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7979565 0.6414085 U 0.4686274 0.6162291 13773 129 184144 184145 1 27 Divergent - + 0.000000 0 0.000000 0.00000000 1.605426 3.545064 1.0923047 - - - hypothetical protein 1.533511 3.698668 1.0537080 - - - hypothetical protein 0.000000e+00 0 5.171807e-03 1.264890e-02 1.255040e-01 6.043083e-01 3.392608e-02 0 0 TRUE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7218001 0.6305306 U 0.4686274 0.6162291 13773 129 184145 184146 1 371 Same + + 0.000000 0 0.000000 0.00000000 1.533511 3.698668 1.0537080 - - - hypothetical protein 1.508771 3.623981 1.2101471 471 Di- and tricarboxylate transporters P conserved hypothetical protein 0.000000e+00 0 6.120604e-04 4.711777e-03 6.706497e-02 3.869693e-01 1.702194e-02 0 8 FALSE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6288167 0.6393080 U 0.4686274 0.6162291 13773 129 184146 184147 1 -31 Convergent + - 0.000000 0 0.000000 0.00000000 1.508771 3.623981 1.2101471 471 Di- and tricarboxylate transporters P conserved hypothetical protein 1.511625 3.646041 1.2169422 - - - ABC-2 type transport system, membrane protein 0.000000e+00 0 8.144664e-06 3.456001e-03 6.199860e-02 3.216145e-01 1.908342e-04 8 0 FALSE FALSE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6005314 0.6545960 U 0.4686274 0.6162291 13773 129 184147 184148 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.511625 3.646041 1.2169422 - - - ABC-2 type transport system, membrane protein 1.362449 3.476284 1.1647191 842 ABC-type multidrug transport system, permease component V ABC-2 type transport system, membrane protein 0.000000e+00 0 2.225349e-02 -5.357278e-03 -3.102403e-02 -4.079658e-01 1.650525e+00 0 0 TRUE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4178218 0.4132931 U 0.4686274 0.6162291 13773 129 184148 184149 1 -28 Same - - 0.000000 0 0.000000 0.00000000 1.362449 3.476284 1.1647191 842 ABC-type multidrug transport system, permease component V ABC-2 type transport system, membrane protein 1.469473 3.240744 1.0474256 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 0.000000e+00 0 1.145424e-02 -1.608148e-03 -1.732521e-02 -1.903477e-01 9.574840e-01 V 0 3 TRUE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4673532 0.4422922 Y 1.4497162 0.7118045 13773 129 184149 184150 1 704 Divergent - + 0.000000 0 0.000000 -0.43323636 1.469473 3.240744 1.0474256 1131 ABC-type multidrug transport system, ATPase component V ABC-2 type transport system ATP-binding protein 1.489034 3.311423 1.1162642 637 Predicted phosphatase/phosphohexomutase R phosphoglycolate phosphatase (pgp), conjectural 1.386361e-03 3 3.826353e-04 6.805756e-04 3.146319e-02 1.165520e-01 2.799137e-02 3 40 TRUE FALSE 102 FALSE 0.4469764 0.2383906 0.5480306 0.4469764 0.7136133 0.4803007 0.5213500 0.6340416 U 0.4686274 0.5377022 13773 129 184150 184151 1 555 Convergent + - 0.000000 0 0.000000 0.00000000 1.489034 3.311423 1.1162642 637 Predicted phosphatase/phosphohexomutase R phosphoglycolate phosphatase (pgp), conjectural 1.564512 3.220068 1.0348875 - - - paREP2b 0.000000e+00 0 5.696821e-03 4.257963e-03 9.942001e-02 3.439786e-01 1.262621e-01 40 0 FALSE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6103763 0.5992342 U 0.4686274 0.6162291 13773 129 184151 184152 1 237 Same - - 0.000000 0 0.000000 0.00000000 1.564512 3.220068 1.0348875 - - - paREP2b 1.278194 3.159309 1.1600496 - - - paREP2b 0.000000e+00 0 8.197770e-02 -1.959203e-02 -1.646534e-01 -7.680369e-01 3.104952e+00 0 0 TRUE FALSE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3841538 0.4007745 U 0.4686274 0.6162291 13773 129 184152 184153 1 105 Divergent - + 0.000000 0 0.000000 0.00000000 1.278194 3.159309 1.1600496 - - - paREP2b 1.374766 3.038256 1.0757664 - - - P. aerophilum family 1964 protein 0.000000e+00 0 9.326082e-03 1.327170e-02 1.146457e-01 6.144295e-01 1.150683e-01 0 0 TRUE FALSE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7251337 0.6018877 U 0.4686274 0.6162291 13773 129 184153 184154 1 182 Same + + 0.000000 0 0.000000 0.00000000 1.374766 3.038256 1.0757664 - - - P. aerophilum family 1964 protein 1.579002 3.689968 1.0831777 - - - hypothetical protein 0.000000e+00 0 4.171227e-02 -9.778283e-03 -6.715061e-02 -5.207606e-01 2.119561e+00 0 0 FALSE FALSE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4023421 0.4070301 U 0.4686274 0.6162291 13773 129 184154 184155 1 218 Convergent + - 0.000000 0 0.000000 0.00000000 1.579002 3.689968 1.0831777 - - - hypothetical protein 1.376564 2.952742 1.0060819 1801 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.098099e-02 -9.548815e-03 -1.180435e-01 -5.074888e-01 2.072893e+00 0 6 FALSE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4048353 0.4073901 U 0.4686274 0.6162291 13773 129 184155 184156 1 39 Divergent - + 0.000000 0 0.000000 -0.13353139 1.376564 2.952742 1.0060819 1801 Uncharacterized conserved protein S conserved hypothetical protein 1.346791 2.883768 0.9562876 - - - conserved hypothetical protein 3.505284e-02 1 8.864511e-04 7.827256e-03 1.258229e-01 4.937729e-01 3.420938e-02 6 1 TRUE FALSE 102 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7716100 0.6703862 0.6303843 U 0.4686274 0.5517368 13773 129 184156 184157 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.346791 2.883768 0.9562876 - - - conserved hypothetical protein 1.249923 2.541840 0.9795289 - - - hypothetical protein 0.000000e+00 0 9.383358e-03 2.107418e-02 3.424356e-01 7.932341e-01 3.564359e-02 1 0 FALSE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7828436 0.6297015 U 0.4686274 0.6162291 13773 129 184157 184158 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.249923 2.541840 0.9795289 - - - hypothetical protein 1.439172 3.057515 1.0831408 1446 Asparaginase E asparaginase 0.000000e+00 0 3.581510e-02 2.462186e-03 -5.317341e-02 1.747546e-02 9.455062e-01 0 14 FALSE FALSE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178537 0.4430303 U 0.4686274 0.6162291 13773 129 184158 184159 1 -3 Same - - 0.000000 0 0.000000 -0.31372225 1.439172 3.057515 1.0831408 1446 Asparaginase E asparaginase 1.290774 2.949834 1.0111545 522 Ribosomal protein S4 and related proteins J ribosomal protein S4 2.214465e-02 6 2.202187e-02 1.962941e-03 1.088249e-01 1.697423e-02 8.910896e-01 0 14 6 TRUE FALSE 103 TRUE 0.4469764 0.2527773 0.5480306 0.4469764 0.7537284 0.6919696 0.5179607 0.4474444 N 0.5492530 0.5510247 13773 129 184159 184160 1 32 Same - - 11.162942 0 16.769561 16.76956109 1.290774 2.949834 1.0111545 522 Ribosomal protein S4 and related proteins J ribosomal protein S4 1.415568 3.129634 1.0651265 99 Ribosomal protein S13 J ribosomal protein S13 2.318511e-03 6 1.557347e-02 5.754182e-03 2.576124e-02 2.479714e-01 4.952789e-01 J 6 41 TRUE FALSE 102 TRUE 2.6369314 1.8883037 0.5480306 2.6514272 0.7537284 0.5021730 0.5686721 0.4929568 Y 1.4497162 0.9177651 13773 129 184160 184161 1 29 Same - - 0.000000 0 0.000000 -0.24140159 1.415568 3.129634 1.0651265 99 Ribosomal protein S13 J ribosomal protein S13 1.592350 3.626881 1.0890554 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP oligopeptide ABC transporter, permease protein 1.111513e-03 3 3.125193e-02 -5.049800e-03 8.891959e-03 -2.202651e-01 1.236653e+00 41 3 TRUE FALSE 101 TRUE 0.4469764 0.2682666 0.5480306 0.4469764 0.7136133 0.4727897 0.4593792 0.4267515 U 0.4686274 0.5471498 13773 129 184161 184162 1 -3 Same - - 5.746842 0 11.353461 11.35346069 1.592350 3.626881 1.0890554 1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP oligopeptide ABC transporter, permease protein 1.579403 3.824023 1.1729522 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP oligopeptide ABC transporter, permease protein 2.978406e-02 3 1.676118e-04 1.804400e-02 2.228701e-01 7.047171e-01 8.505079e-04 3 11 TRUE FALSE 100 TRUE 2.7746139 1.8596033 0.5480306 2.7198489 0.7136133 0.7347716 0.7545308 0.6520519 U 0.4686274 0.8730427 13773 129 184162 184163 1 50 Same - - 5.669881 0 5.669881 5.66988092 1.579403 3.824023 1.1729522 601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components EP oligopeptide ABC transporter, permease protein 1.623356 3.486957 1.0810143 3889 Predicted solute binding protein R oligopeptide binding protein, putative 5.377067e-02 2 1.931836e-03 2.201311e-02 3.116037e-01 7.439736e-01 5.889944e-03 11 2 TRUE FALSE 99 TRUE 2.7848973 1.8012140 0.5480306 2.8401840 0.6838149 0.8640648 0.7653307 0.6456836 U 0.4686274 0.8644161 13773 129 184163 184164 1 246 Same - - 0.000000 0 0.000000 0.00000000 1.623356 3.486957 1.0810143 3889 Predicted solute binding protein R oligopeptide binding protein, putative 1.516158 3.475877 1.1617088 4945 Membrane-anchored protein predicted to be involved in regulation of amylopullulanase G pullulanase 0.000000e+00 0 1.149132e-02 1.113731e-02 8.651370e-02 5.418896e-01 9.050724e-02 2 0 TRUE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6938559 0.6107212 U 0.4686274 0.6162291 13773 129 184164 184165 1 615 Same - - 0.000000 0 0.000000 0.00000000 1.516158 3.475877 1.1617088 4945 Membrane-anchored protein predicted to be involved in regulation of amylopullulanase G pullulanase 1.328157 2.829538 0.9666244 180 Tryptophanyl-tRNA synthetase J tryptophanyl-tRNA synthetase 0.000000e+00 0 3.534466e-02 -7.981465e-03 -4.466816e-02 -5.248258e-01 2.173531e+00 0 0 25 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4018867 0.4062445 N 0.5492530 0.6245624 13773 129 184165 184166 1 35 Same - - 0.000000 0 0.000000 0.00000000 1.328157 2.829538 0.9666244 180 Tryptophanyl-tRNA synthetase J tryptophanyl-tRNA synthetase 1.362000 3.047450 1.0672818 177 Predicted EndoIII-related endonuclease L DNA-(apurinic or apyrimidinic site) lyase, conjectural 0.000000e+00 0 1.145344e-03 1.101647e-02 1.312710e-01 6.220158e-01 2.597465e-02 0 25 0 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7272311 0.6350049 N 0.5492530 0.6245624 13773 129 184166 184167 1 75 Same - - 0.000000 0 0.000000 0.00000000 1.362000 3.047450 1.0672818 177 Predicted EndoIII-related endonuclease L DNA-(apurinic or apyrimidinic site) lyase, conjectural 1.368357 3.035761 1.0375061 5014 Predicted Fe-S oxidoreductase R molybdenum cofactor biosynthesis protein (moaA) 0.000000e+00 0 4.041077e-05 7.422874e-03 1.047444e-01 4.804498e-01 1.414176e-03 0 2 TRUE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6665569 0.6511912 U 0.4686274 0.6162291 13773 129 184167 184168 1 210 Divergent - + 0.000000 0 0.000000 -0.06062462 1.368357 3.035761 1.0375061 5014 Predicted Fe-S oxidoreductase R molybdenum cofactor biosynthesis protein (moaA) 1.452508 3.186439 1.0998393 2097 Ribosomal protein L31E J ribosomal protein L31 1.349135e-02 2 7.081479e-03 -9.260939e-05 2.148077e-03 -7.403483e-02 6.151952e-01 2 8 TRUE FALSE 94 FALSE 0.4469764 0.3041435 0.5480306 0.4469764 0.6838149 0.6281588 0.5001749 0.4752630 U 0.4686274 0.5584497 13773 129 184168 184169 1 0 Same + + 19.942188 0 22.139412 22.13941216 1.452508 3.186439 1.0998393 2097 Ribosomal protein L31E J ribosomal protein L31 1.323304 3.026093 1.0816571 1976 Translation initiation factor 6 (eIF-6) J translation initiation factor aIF-6 2.393230e-01 8 1.669365e-02 -1.428558e-04 6.072917e-02 -9.744971e-02 9.954005e-01 J 8 12 FALSE FALSE 95 TRUE 2.3799019 1.9298876 0.5480306 2.5564277 0.7652913 1.1721472 0.4926112 0.4395482 Y 1.4497162 0.9239461 13773 129 184169 184170 1 57 Same + + 2.890372 0 2.890372 2.87235325 1.323304 3.026093 1.0816571 1976 Translation initiation factor 6 (eIF-6) J translation initiation factor aIF-6 1.327226 2.919822 1.0483733 2157 Ribosomal protein L20A (L18A) J ribosomal protein LX 5.118686e-02 2 1.538022e-05 1.590436e-02 2.041836e-01 7.789162e-01 1.154429e-04 J 12 2 FALSE FALSE 96 TRUE 2.8691690 1.7403663 0.5480306 2.9115413 0.6838149 0.8456214 0.7772606 0.6549470 Y 1.4497162 0.8998068 13773 129 184170 184171 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.327226 2.919822 1.0483733 2157 Ribosomal protein L20A (L18A) J ribosomal protein LX 1.357444 3.057758 1.0693971 1730 Predicted prefoldin, molecular chaperone implicated in de novo protein folding O conserved hypothetical protein 0.000000e+00 0 9.131374e-04 1.166531e-02 1.403938e-01 6.442721e-01 2.037685e-02 0 2 0 FALSE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7348685 0.6373256 N 0.5492530 0.6245624 13773 129 184171 184172 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.357444 3.057758 1.0693971 1730 Predicted prefoldin, molecular chaperone implicated in de novo protein folding O conserved hypothetical protein 1.433457 3.070995 1.0587444 552 Signal recognition particle GTPase U signal recognition particle protein (docking protein), probable 0.000000e+00 0 5.777985e-03 1.685029e-03 1.884184e-02 5.242109e-02 4.396820e-01 0 0 12 FALSE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187795 0.5054889 N 0.5492530 0.6245624 13773 129 184172 184173 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.433457 3.070995 1.0587444 552 Signal recognition particle GTPase U signal recognition particle protein (docking protein), probable 1.444763 3.445529 1.1375239 - - - hypothetical protein 0.000000e+00 0 1.278154e-04 1.189148e-04 2.142278e-02 -2.245836e-03 1.057598e-02 12 0 FALSE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199125 0.6424418 U 0.4686274 0.6162291 13773 129 184173 184174 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.444763 3.445529 1.1375239 - - - hypothetical protein 1.461024 3.172987 1.0629700 250 Transcription antiterminator K transcription antitermination protein nusG, putative 0.000000e+00 0 2.644251e-04 -6.385480e-05 2.011501e-02 5.916449e-03 2.451159e-02 0 11 FALSE FALSE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5193869 0.6356211 U 0.4686274 0.6162291 13773 129 184174 184175 1 36 Same + + 20.533813 0 31.000244 30.92020145 1.461024 3.172987 1.0629700 250 Transcription antiterminator K transcription antitermination protein nusG, putative 1.362695 2.965688 1.0422739 80 Ribosomal protein L11 J ribosomal protein L11 4.243113e-02 11 9.668546e-03 -8.542534e-04 3.049299e-02 -1.333366e-01 8.048968e-01 0 11 44 FALSE FALSE 101 TRUE 2.3661331 1.9785636 0.5480306 2.4071570 0.7764261 0.8151714 0.4810088 0.4547804 N 0.5492530 0.8971298 13773 129 184175 184176 1 -3 Same + + 58.970581 0 82.497934 82.16976074 1.362695 2.965688 1.0422739 80 Ribosomal protein L11 J ribosomal protein L11 1.368653 2.992130 1.0379044 81 Ribosomal protein L1 J ribosomal protein L1 -4.174930e-02 44 3.549320e-05 7.338855e-03 1.039519e-01 4.756577e-01 1.472486e-03 J 44 57 FALSE FALSE 102 TRUE 2.0419822 2.0676247 0.5480306 2.0808318 0.7723149 0.5246430 0.6648349 0.6510547 Y 1.4497162 0.9378827 13773 129 184176 184177 1 40 Same + + 21.765172 0 29.215252 29.21525165 1.368653 2.992130 1.0379044 81 Ribosomal protein L1 J ribosomal protein L1 1.344258 2.966508 1.0414355 244 Ribosomal protein L10 J acidic ribosomal protein P0 (L10E) 3.831506e-02 10 5.951189e-04 8.864370e-03 1.361454e-01 5.446384e-01 1.994099e-02 J 57 10 FALSE FALSE 103 TRUE 2.3164721 1.9657770 0.5480306 2.4469457 0.7739415 0.7923188 0.6950064 0.6374861 Y 1.4497162 0.9276274 13773 129 184177 184178 1 16 Same + + 0.000000 0 0.000000 -0.73190692 1.344258 2.966508 1.0414355 244 Ribosomal protein L10 J acidic ribosomal protein P0 (L10E) 1.433107 3.153237 1.0569607 1577 Mevalonate kinase I mevalonate kinase 1.600341e-01 10 7.894263e-03 1.959017e-03 1.534384e-02 6.044614e-02 5.439487e-01 0 10 13 FALSE FALSE 104 TRUE 0.4469764 0.2226932 0.5480306 0.4469764 0.7739415 1.0996350 0.5185505 0.4843660 N 0.5492530 0.5415244 13773 129 184178 184179 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.433107 3.153237 1.0569607 1577 Mevalonate kinase I mevalonate kinase 1.470226 3.763483 1.2243997 - - - hypothetical protein 0.000000e+00 0 1.377776e-03 -3.443691e-04 1.676283e-02 -2.022489e-02 1.198021e-01 13 0 FALSE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5154241 0.6010459 U 0.4686274 0.6162291 13773 129 184179 184180 1 16 Same + + 0.000000 0 0.000000 0.00000000 1.470226 3.763483 1.2243997 - - - hypothetical protein 1.438811 3.116363 1.0535641 2820 Uridine phosphorylase F uridine phosphorylase 0.000000e+00 0 9.869039e-04 -2.369577e-04 1.746843e-02 -7.923153e-03 9.050724e-02 0 15 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192381 0.6107212 U 0.4686274 0.6162291 13773 129 184180 184181 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.438811 3.116363 1.0535641 2820 Uridine phosphorylase F uridine phosphorylase 1.399048 3.099869 1.0792486 - - - hypothetical protein 0.000000e+00 0 1.581076e-03 6.586075e-04 3.499450e-02 1.257856e-02 1.617237e-01 15 0 FALSE FALSE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185743 0.5896102 U 0.4686274 0.6162291 13773 129 184181 184182 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.399048 3.099869 1.0792486 - - - hypothetical protein 1.427614 3.143614 1.0573621 4080 RecB-family nuclease L conserved hypothetical protein 0.000000e+00 0 8.159978e-04 1.244717e-03 2.976902e-02 6.189978e-02 8.282734e-02 0 2 FALSE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184094 0.6132788 U 0.4686274 0.6162291 13773 129 184182 184183 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.427614 3.143614 1.0573621 4080 RecB-family nuclease L conserved hypothetical protein 1.427689 3.125520 1.0906589 1712 Predicted dinucleotide-utilizing enzyme R nicotinate-nucleotide pyrophosphorylase AND conserved protein 0.000000e+00 0 5.646819e-09 5.636617e-04 2.731912e-02 2.048640e-02 5.889944e-07 2 0 FALSE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176236 0.6559820 U 0.4686274 0.6162291 13773 129 184183 184184 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.427689 3.125520 1.0906589 1712 Predicted dinucleotide-utilizing enzyme R nicotinate-nucleotide pyrophosphorylase AND conserved protein 1.359563 2.920612 1.0427335 379 Quinolinate synthase H quinolinate synthetase A 0.000000e+00 0 4.641070e-03 2.176726e-03 6.617645e-02 1.033084e-01 3.375227e-01 0 46 TRUE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190998 0.5282099 U 0.4686274 0.6162291 13773 129 184184 184185 1 104 Same - - 0.000000 0 0.000000 0.00000000 1.359563 2.920612 1.0427335 379 Quinolinate synthase H quinolinate synthetase A 1.503549 3.415555 1.1543291 61 Predicted sugar kinase G conserved hypothetical protein 0.000000e+00 0 2.073174e-02 -4.789436e-03 -4.976846e-02 -3.821301e-01 1.566820e+00 0 46 0 TRUE FALSE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4222664 0.4151533 N 0.5492530 0.6245624 13773 129 184185 184186 1 9 Same - - 0.000000 0 0.000000 0.00000000 1.503549 3.415555 1.1543291 61 Predicted sugar kinase G conserved hypothetical protein 1.403588 2.946256 1.0037612 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 0.000000e+00 0 9.992076e-03 -2.493286e-03 -9.519061e-03 -2.018036e-01 8.284772e-01 0 0 0 TRUE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4638104 0.4521115 N 0.5492530 0.6245624 13773 129 184186 184187 1 27 Same - - 0.000000 0 0.000000 0.00000000 1.403588 2.946256 1.0037612 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 1.546706 3.594299 1.1497608 1079 Uncharacterized ABC-type transport system, permease component R ribose ABC transporter, permease protein 0.000000e+00 0 2.048280e-02 -4.556425e-03 -1.527018e-02 -2.807065e-01 1.246916e+00 0 36 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4452427 0.4261574 U 0.4686274 0.6162291 13773 129 184187 184188 1 -3 Same - - 40.888118 0 67.464862 66.97821439 1.546706 3.594299 1.1497608 1079 Uncharacterized ABC-type transport system, permease component R ribose ABC transporter, permease protein 1.391263 3.361726 1.1740136 4603 ABC-type uncharacterized transport system, permease component R ribose ABC transporter, permease protein 3.494012e-01 29 2.416257e-02 -5.731165e-03 -6.016154e-02 -3.613110e-01 1.504058e+00 36 29 TRUE FALSE 104 TRUE 2.0945060 2.0544067 0.5480306 2.1326860 0.7756873 1.2446717 0.4257877 0.4168764 U 0.4686274 0.9055657 13773 129 184188 184189 1 -3 Same - - 37.991811 0 75.073733 74.77809375 1.391263 3.361726 1.1740136 4603 ABC-type uncharacterized transport system, permease component R ribose ABC transporter, permease protein 1.457634 3.165580 1.1109851 3845 ABC-type uncharacterized transport systems, ATPase components R ribose ABC transport system ATP-binding 2.481876e-01 29 4.405074e-03 -3.752772e-04 7.266996e-03 -7.437645e-02 4.136178e-01 29 42 TRUE FALSE 103 TRUE 2.1030874 2.0610077 0.5480306 2.1069815 0.7756873 1.1871904 0.5000034 0.5101580 U 0.4686274 0.9061921 13773 129 184189 184190 1 0 Same - - 18.531347 0 26.130396 26.02671778 1.457634 3.165580 1.1109851 3845 ABC-type uncharacterized transport systems, ATPase components R ribose ABC transport system ATP-binding 1.363853 2.955727 1.0443157 1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein R sugar binding protein 9.398390e-02 11 8.794799e-03 -5.463460e-04 3.371139e-02 -1.062852e-01 7.296280e-01 42 11 TRUE FALSE 102 TRUE 2.4523295 1.9467144 0.5480306 2.5095833 0.7764261 0.9909368 0.4890786 0.4617333 U 0.4686274 0.8888532 13773 129 184190 184191 1 23 Same - - 0.000000 0 0.000000 0.00000000 1.363853 2.955727 1.0443157 1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein R sugar binding protein 1.520383 3.538968 1.1151677 - - - hypothetical protein 0.000000e+00 0 2.450156e-02 -6.039371e-03 -5.724979e-02 -4.386288e-01 1.760764e+00 11 0 TRUE FALSE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4132793 0.4111960 U 0.4686274 0.6162291 13773 129 184191 184192 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.520383 3.538968 1.1151677 - - - hypothetical protein 1.503401 3.250005 1.1175356 2366 Protein related to penicillin acylase R penicillin amidase 0.000000e+00 0 2.884018e-04 3.588039e-03 5.747176e-02 3.289716e-01 9.350875e-03 0 6 TRUE FALSE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6031483 0.6432396 U 0.4686274 0.6162291 13773 129 184192 184193 1 81 Same - - 0.000000 0 0.000000 0.00000000 1.503401 3.250005 1.1175356 2366 Protein related to penicillin acylase R penicillin amidase 1.609982 3.841900 1.1457547 - - - P. aerophilum family 70 protein 0.000000e+00 0 1.135962e-02 8.247900e-03 1.741757e-01 4.657397e-01 1.268081e-01 6 0 TRUE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6621035 0.5988589 U 0.4686274 0.6162291 13773 129 184193 184194 1 -30 Same - - 0.000000 0 0.000000 0.00000000 1.609982 3.841900 1.1457547 - - - P. aerophilum family 70 protein 1.594513 3.601166 1.1341256 - - - P. aerophilum family 68 protein, part 2, authentic frameshift 0.000000e+00 0 2.393070e-04 2.269730e-02 2.742682e-01 7.572507e-01 6.808775e-04 0 0 TRUE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7694339 0.6526075 U 0.4686274 0.6162291 13773 129 184194 184195 1 97 Same - - 0.000000 0 0.000000 0.00000000 1.594513 3.601166 1.1341256 - - - P. aerophilum family 68 protein, part 2, authentic frameshift 1.586645 3.567309 1.1263459 - - - P. aerophilum family 68 protein, part 1, authentic frameshift 0.000000e+00 0 6.190086e-05 1.935727e-02 2.415064e-01 7.217237e-01 2.355978e-04 0 0 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7608053 0.6542630 U 0.4686274 0.6162291 13773 129 184195 184196 1 150 Divergent - + 0.000000 0 0.000000 0.00000000 1.586645 3.567309 1.1263459 - - - P. aerophilum family 68 protein, part 1, authentic frameshift 1.498452 3.168518 1.0292089 - - - hypothetical protein 0.000000e+00 0 7.777936e-03 6.364905e-03 5.432634e-02 4.193363e-01 1.182135e-01 0 0 TRUE FALSE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6434625 0.6012841 U 0.4686274 0.6162291 13773 129 184196 184197 1 1 Same + + 0.000000 0 0.000000 0.00000000 1.498452 3.168518 1.0292089 - - - hypothetical protein 1.404411 3.094152 1.0541372 3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon K conserved hypothetical protein 0.000000e+00 0 8.843762e-03 -2.210939e-03 -5.131812e-03 -1.842481e-01 7.534187e-01 0 7 FALSE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4690090 0.4592446 U 0.4686274 0.6162291 13773 129 184197 184198 1 183 Same + + 0.000000 0 0.000000 -0.63415686 1.404411 3.094152 1.0541372 3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon K conserved hypothetical protein 1.428890 3.135361 1.0944441 585 Uncharacterized conserved protein S conserved hypothetical protein 1.648650e-01 7 5.992140e-04 1.057224e-03 2.877959e-02 4.769441e-02 5.807249e-02 7 16 FALSE FALSE 98 TRUE 0.4469764 0.2287048 0.5480306 0.4469764 0.7596462 1.1056755 0.5187200 0.6210721 U 0.4686274 0.5346331 13773 129 184198 184199 1 37 Same + + 0.000000 0 0.000000 0.00000000 1.428890 3.135361 1.0944441 585 Uncharacterized conserved protein S conserved hypothetical protein 1.392558 3.078455 1.0416103 2006 Uncharacterized conserved protein S hypothetical protein 0.000000e+00 0 1.319995e-03 1.323949e-03 4.372225e-02 6.164651e-02 1.219366e-01 16 0 FALSE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184218 0.6003415 U 0.4686274 0.6162291 13773 129 184199 184200 1 107 Same + + 0.000000 0 0.000000 0.00000000 1.392558 3.078455 1.0416103 2006 Uncharacterized conserved protein S hypothetical protein 1.431923 3.037424 1.0633015 93 Ribosomal protein L14 J ribosomal protein L14 0.000000e+00 0 1.549623e-03 1.145473e-03 2.630296e-02 4.366628e-02 1.496140e-01 0 54 FALSE FALSE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184464 0.5933123 U 0.4686274 0.6162291 13773 129 184200 184201 1 68 Same + + 0.000000 0 0.000000 0.00000000 1.431923 3.037424 1.0633015 93 Ribosomal protein L14 J ribosomal protein L14 1.375530 3.027612 1.0574483 - - - hypothetical protein 0.000000e+00 0 3.180237e-03 1.477004e-03 5.165998e-02 5.726380e-02 2.869604e-01 54 0 FALSE FALSE 101 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186677 0.5481348 U 0.4686274 0.6162291 13773 129 184201 184202 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.375530 3.027612 1.0574483 - - - hypothetical protein 1.458692 3.221318 1.0870502 - - - hypothetical protein 0.000000e+00 0 6.915878e-03 -5.537083e-04 -2.164922e-04 -1.020162e-01 6.236514e-01 0 0 FALSE FALSE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4902313 0.4741862 U 0.4686274 0.6162291 13773 129 184202 184203 1 34 Convergent + - 0.000000 0 0.000000 0.00000000 1.458692 3.221318 1.0870502 - - - hypothetical protein 1.476490 3.206261 1.1041831 499 S-adenosylhomocysteine hydrolase H adenosylhomocysteinase 0.000000e+00 0 3.167651e-04 1.831756e-04 2.434364e-02 5.381760e-02 2.824876e-02 0 41 FALSE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187635 0.6339124 U 0.4686274 0.6162291 13773 129 184203 184204 1 168 Same - - 0.000000 0 0.000000 0.00000000 1.476490 3.206261 1.1041831 499 S-adenosylhomocysteine hydrolase H adenosylhomocysteinase 1.416475 3.150911 1.0549748 - - - hypothetical protein 0.000000e+00 0 3.601768e-03 -8.763273e-04 1.198828e-02 -8.275725e-02 3.375227e-01 41 0 TRUE FALSE 102 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4972060 0.5282099 U 0.4686274 0.6162291 13773 129 184204 184205 1 837 Divergent - + 0.000000 0 0.000000 0.00000000 1.416475 3.150911 1.0549748 - - - hypothetical protein 1.480385 3.138291 1.0444649 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 0.000000e+00 0 4.084521e-03 -1.012351e-03 7.939229e-03 -9.178182e-02 3.807354e-01 0 13 TRUE FALSE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4948416 0.5167658 U 0.4686274 0.6162291 13773 129 184205 184206 1 2 Same + + 0.000000 0 0.000000 -0.13353139 1.480385 3.138291 1.0444649 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 1.439746 3.193538 1.0463715 1318 Predicted transcriptional regulators K conserved hypothetical protein 2.394346e-02 1 1.651514e-03 -3.376609e-04 1.499955e-02 -4.504629e-03 1.437358e-01 0 13 1 FALSE FALSE 102 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7020387 0.5197274 0.5944258 N 0.5492530 0.5604716 13773 129 184206 184207 1 -9 Same + + 0.000000 0 0.000000 0.00000000 1.439746 3.193538 1.0463715 1318 Predicted transcriptional regulators K conserved hypothetical protein 1.416526 3.088685 1.0431896 3382 Uncharacterized conserved protein S conserved hypothetical protein 5.631536e-04 1 5.391642e-04 4.060765e-04 2.822840e-02 3.062771e-03 5.623777e-02 1 3 FALSE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.5197160 0.6216788 U 0.4686274 0.6162291 13773 129 184207 184208 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.416526 3.088685 1.0431896 3382 Uncharacterized conserved protein S conserved hypothetical protein 1.432177 3.076001 1.0617002 2403 Predicted GTPase R conserved hypothetical protein 2.897430e-03 3 2.449338e-04 6.700002e-04 2.642205e-02 2.239651e-02 2.548225e-02 3 5 FALSE FALSE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5139075 0.5175067 0.6352777 U 0.4686274 0.6162291 13773 129 184208 184209 1 104 Divergent - + 0.000000 0 0.000000 0.00000000 1.432177 3.076001 1.0617002 2403 Predicted GTPase R conserved hypothetical protein 1.388633 2.987831 1.0466462 - - - hypothetical protein 0.000000e+00 0 1.896081e-03 1.206009e-03 4.390366e-02 4.589562e-02 1.775235e-01 5 0 TRUE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5186126 0.5856408 U 0.4686274 0.6162291 13773 129 184209 184210 1 -38 Convergent + - 0.000000 0 0.000000 0.00000000 1.388633 2.987831 1.0466462 - - - hypothetical protein 1.559367 3.419296 1.1085914 - - - hypothetical protein 0.000000e+00 0 2.915015e-02 -6.776465e-03 -3.889079e-02 -3.954084e-01 1.650525e+00 0 0 FALSE FALSE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4201626 0.4132931 U 0.4686274 0.6162291 13773 129 184210 184211 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.559367 3.419296 1.1085914 - - - hypothetical protein 1.311572 2.841565 1.0152027 1651 Protein-disulfide isomerase O thiol:disulphide interchange protein, putative 0.000000e+00 0 6.140206e-02 -1.509697e-02 -1.357401e-01 -7.112602e-01 2.866304e+00 0 0 TRUE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3860542 0.4013896 U 0.4686274 0.6162291 13773 129 184211 184212 1 115 Divergent - + 0.000000 0 0.000000 0.00000000 1.311572 2.841565 1.0152027 1651 Protein-disulfide isomerase O thiol:disulphide interchange protein, putative 1.330626 2.894609 1.0073830 5494 Predicted thioredoxin/glutaredoxin O conserved hypothetical protein 0.000000e+00 0 3.630559e-04 1.688561e-02 2.055597e-01 7.973453e-01 2.723510e-03 O 0 1 TRUE FALSE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7847151 0.6489041 Y 1.4497162 0.7118045 13773 129 184212 184213 1 74 Same + + 0.000000 0 0.000000 0.00000000 1.330626 2.894609 1.0073830 5494 Predicted thioredoxin/glutaredoxin O conserved hypothetical protein 1.312369 2.834289 1.0135409 209 Ribonucleotide reductase, alpha subunit F ribonucleotide reductase 1.233696e-02 1 3.333435e-04 1.678944e-02 2.290898e-01 7.953486e-01 2.488501e-03 0 1 44 FALSE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.6186769 0.7833110 0.6493745 N 0.5492530 0.6245624 13773 129 184213 184214 1 52 Same + + 0.000000 0 0.000000 0.00000000 1.312369 2.834289 1.0135409 209 Ribonucleotide reductase, alpha subunit F ribonucleotide reductase 1.468302 3.688066 1.2412352 - - - hypothetical protein 0.000000e+00 0 2.431514e-02 -2.350766e-03 -5.510489e-02 -2.315661e-01 1.367984e+00 44 0 FALSE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4564630 0.4212714 U 0.4686274 0.6162291 13773 129 184214 184215 1 35 Same + + 0.000000 0 0.000000 0.00000000 1.468302 3.688066 1.2412352 - - - hypothetical protein 1.682625 3.641870 1.0950847 - - - hypothetical protein 0.000000e+00 0 4.593457e-02 3.909924e-03 2.015113e-01 2.424177e-01 5.006947e-01 0 0 FALSE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5662244 0.4924234 U 0.4686274 0.6162291 13773 129 184215 184216 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.682625 3.641870 1.0950847 - - - hypothetical protein 1.420697 3.038400 1.0403705 172 Seryl-tRNA synthetase J seryl-tRNA synthetase 0.000000e+00 0 6.860645e-02 -7.097856e-03 -1.956434e-01 -2.026288e-01 1.371577e+00 0 64 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4633764 0.4208351 U 0.4686274 0.6162291 13773 129 184216 184217 1 113 Convergent + - 0.000000 0 0.000000 -2.89871580 1.420697 3.038400 1.0403705 172 Seryl-tRNA synthetase J seryl-tRNA synthetase 1.504439 3.336620 1.1124236 528 Uridylate kinase F uridylate kinase (pyrH) 1.223715e-02 23 7.012648e-03 -1.628281e-03 6.452395e-03 -1.130575e-01 5.576181e-01 0 64 23 FALSE FALSE 107 FALSE 0.4469764 0.1914758 0.5480306 0.4469764 0.7771174 0.6167113 0.4875691 0.4828600 N 0.5492530 0.5316343 13773 129 184217 184218 1 -16 Same - - 0.000000 0 0.000000 0.00000000 1.504439 3.336620 1.1124236 528 Uridylate kinase F uridylate kinase (pyrH) 1.505261 3.144117 1.0561639 - - - hypothetical protein 0.000000e+00 0 6.758436e-07 2.857467e-03 5.437120e-02 2.886049e-01 9.423910e-06 23 0 TRUE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5883956 0.6557762 U 0.4686274 0.6162291 13773 129 184218 184219 1 249 Divergent - + 0.000000 0 0.000000 0.00000000 1.505261 3.144117 1.0561639 - - - hypothetical protein 1.504823 3.103619 1.0277689 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR HIT family protein 0.000000e+00 0 1.916896e-07 2.878167e-03 5.427072e-02 2.894319e-01 2.355978e-06 0 43 TRUE FALSE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5893811 0.6559187 U 0.4686274 0.6162291 13773 129 184219 184220 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.504823 3.103619 1.0277689 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR HIT family protein 1.499631 3.394702 1.1496449 2771 DNA-binding HTH domain-containing proteins K regulatory protein, luxR family, conjectural 0.000000e+00 0 2.696032e-05 2.577347e-03 4.953216e-02 2.717031e-01 9.900996e-04 43 0 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5804334 0.6518633 U 0.4686274 0.6162291 13773 129 184220 184221 1 -7 Convergent + - 0.000000 0 0.000000 0.00000000 1.499631 3.394702 1.1496449 2771 DNA-binding HTH domain-containing proteins K regulatory protein, luxR family, conjectural 1.402085 3.025718 1.0510088 12 Predicted GTPase, probable translation factor J GTP binding protein, putative 0.000000e+00 0 9.515148e-03 -2.378501e-03 -6.807319e-03 -2.002840e-01 8.131804e-01 0 0 12 FALSE FALSE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4646726 0.4538896 N 0.5492530 0.6245624 13773 129 184221 184222 1 142 Divergent - + 0.000000 0 0.000000 0.00000000 1.402085 3.025718 1.0510088 12 Predicted GTPase, probable translation factor J GTP binding protein, putative 1.455600 2.921928 1.0705017 - - - paREP2a 0.000000e+00 0 2.863838e-03 -2.074367e-04 1.218301e-02 -5.349012e-02 2.820482e-01 12 0 TRUE FALSE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5057814 0.5503270 U 0.4686274 0.6162291 13773 129 184222 184223 1 67 Same + + 0.000000 0 0.000000 0.00000000 1.455600 2.921928 1.0705017 - - - paREP2a 1.467061 3.437780 1.1577445 - - - hypothetical protein 0.000000e+00 0 1.313523e-04 6.591427e-05 2.208684e-02 3.255019e-02 1.121681e-02 0 0 FALSE FALSE 107 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174404 0.6422810 U 0.4686274 0.6162291 13773 129 184223 184224 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.467061 3.437780 1.1577445 - - - hypothetical protein 1.391745 3.052555 1.0953250 517 FOG: CBS domain R conserved protein with 7 CBS domains 0.000000e+00 0 5.672433e-03 -9.345523e-04 1.822242e-02 -1.172546e-01 5.293316e-01 0 1 FALSE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4858098 0.4876243 U 0.4686274 0.6162291 13773 129 184224 184225 1 34 Same + + 0.000000 0 0.000000 -0.13353139 1.391745 3.052555 1.0953250 517 FOG: CBS domain R conserved protein with 7 CBS domains 1.382780 2.937207 1.0434724 464 ATPases of the AAA+ class O AAA family ATPase, possible cell division control protein cdc48 3.085292e-02 1 8.037863e-05 4.092612e-03 7.150987e-02 2.737187e-01 5.772734e-03 1 8 FALSE FALSE 109 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7379657 0.5818594 0.6458271 U 0.4686274 0.5517368 13773 129 184225 184226 1 31 Same + + 7.599902 0 12.590335 12.39492775 1.382780 2.937207 1.0434724 464 ATPases of the AAA+ class O AAA family ATPase, possible cell division control protein cdc48 1.230858 2.439416 0.8632980 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 1.398539e-01 6 2.308010e-02 1.513155e-02 3.092148e-01 5.599576e-01 1.873568e-01 O 8 6 FALSE FALSE 110 TRUE 2.7176749 1.8698150 0.5480306 2.6936340 0.7537284 1.0797335 0.7031812 0.5834990 Y 1.4497162 0.9151959 13773 129 184226 184227 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.230858 2.439416 0.8632980 71 Molecular chaperone (small heat shock protein) O small heat shock protein, hsp20 homolog, conjectural 1.436517 2.987451 1.0111472 4345 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.150801e-03 1 4.229541e-02 3.280670e-03 -6.385199e-02 4.812732e-02 8.968948e-01 6 1 FALSE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4759583 0.5187480 0.4466307 U 0.4686274 0.6162291 13773 129 184227 184228 1 66 Divergent - + 0.000000 0 0.000000 0.00000000 1.436517 2.987451 1.0111472 4345 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.385898 2.935045 1.0166277 1818 Predicted RNA-binding protein, contains THUMP domain R conserved hypothetical protein 9.520652e-04 1 2.562248e-03 9.742980e-04 4.246082e-02 2.627151e-02 2.450364e-01 1 5 TRUE FALSE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.5173835 0.5644275 U 0.4686274 0.6162291 13773 129 184228 184229 1 67 Same + + 0.000000 0 0.000000 0.00000000 1.385898 2.935045 1.0166277 1818 Predicted RNA-binding protein, contains THUMP domain R conserved hypothetical protein 1.507354 3.485963 1.1456664 - - - conserved within P. aerophilum part 1, authentic frameshift 0.000000e+00 0 1.475147e-02 -3.665145e-03 -2.505675e-02 -2.994118e-01 1.197706e+00 5 0 FALSE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4403971 0.4280077 U 0.4686274 0.6162291 13773 129 184229 184230 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.507354 3.485963 1.1456664 - - - conserved within P. aerophilum part 1, authentic frameshift 1.381049 3.056561 1.0574568 - - - conserved within P. aerophilum part 2, authentic frameshift 0.000000e+00 0 1.595286e-02 -3.936499e-03 -2.067571e-02 -3.171735e-01 1.269297e+00 0 0 FALSE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4357063 0.4255677 U 0.4686274 0.6162291 13773 129 184230 184231 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.381049 3.056561 1.0574568 - - - conserved within P. aerophilum part 2, authentic frameshift 1.488658 3.301205 1.1054218 100 Ribosomal protein S11 J ribosomal protein S11 0.000000e+00 0 1.157968e-02 -2.621377e-03 -1.895162e-02 -2.491446e-01 1.016955e+00 0 60 FALSE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4523237 0.4380418 U 0.4686274 0.6162291 13773 129 184231 184232 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.488658 3.301205 1.1054218 100 Ribosomal protein S11 J ribosomal protein S11 1.289877 2.739050 0.9402393 - - - hypothetical protein 0.000000e+00 0 3.951399e-02 -6.018942e-03 1.308510e-02 -4.172342e-01 1.950985e+00 60 0 FALSE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4158865 0.4088885 U 0.4686274 0.6162291 13773 129 184232 184233 1 280 Same + + 0.000000 0 0.000000 0.00000000 1.289877 2.739050 0.9402393 - - - hypothetical protein 1.506759 3.266681 1.1208456 - - - hypothetical protein 0.000000e+00 0 4.703794e-02 -8.942552e-03 -1.422856e-01 -5.296803e-01 2.290472e+00 0 0 FALSE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4009738 0.4051162 U 0.4686274 0.6162291 13773 129 184233 184234 1 174 Convergent + - 0.000000 0 0.000000 0.00000000 1.506759 3.266681 1.1208456 - - - hypothetical protein 1.519897 3.650520 1.1682990 - - - hypothetical protein 0.000000e+00 0 1.726097e-04 3.792843e-03 6.921754e-02 3.399063e-01 4.770855e-03 0 0 FALSE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6082095 0.6465274 U 0.4686274 0.6162291 13773 129 184234 184235 1 135 Divergent - + 0.000000 0 0.000000 0.00000000 1.519897 3.650520 1.1682990 - - - hypothetical protein 1.293049 2.679728 0.9235114 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 0.000000e+00 0 5.146020e-02 -1.084727e-02 -5.433655e-02 -5.924624e-01 2.484918e+00 0 19 TRUE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3949798 0.4034139 U 0.4686274 0.6162291 13773 129 184235 184236 1 1337 Same + + 0.000000 0 0.000000 0.00000000 1.293049 2.679728 0.9235114 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 1.449543 3.363205 1.0714188 - - - paREP9, associated with SRSRs 0.000000e+00 0 2.449029e-02 2.929696e-04 -3.950074e-02 -7.571170e-02 1.075033e+00 19 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4993948 0.4346034 U 0.4686274 0.6162291 13773 129 184236 184237 1 304 Same + + 0.000000 0 0.000000 0.00000000 1.449543 3.363205 1.0714188 - - - paREP9, associated with SRSRs 1.305066 2.876730 0.9604123 1392 Phosphate transport regulator (distant homolog of PhoU) P conserved hypothetical protein 0.000000e+00 0 2.087352e-02 2.707356e-04 7.826939e-02 -7.370970e-02 1.023156e+00 0 1 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5002603 0.4376225 U 0.4686274 0.6162291 13773 129 184237 184238 1 0 Same + + 0.000000 0 0.000000 0.00000000 1.305066 2.876730 0.9604123 1392 Phosphate transport regulator (distant homolog of PhoU) P conserved hypothetical protein 1.289436 3.306934 1.1122991 - - - hypothetical protein 0.000000e+00 0 2.442855e-04 2.369861e-02 3.100647e-01 9.009759e-01 1.140293e-03 1 0 FALSE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8051477 0.6516922 U 0.4686274 0.6162291 13773 129 184238 184239 1 -43 Convergent + - 0.000000 0 0.000000 0.00000000 1.289436 3.306934 1.1122991 - - - hypothetical protein 1.291991 2.706677 0.9534978 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R conserved hypothetical protein 0.000000e+00 0 6.525048e-06 2.581622e-02 3.205036e-01 9.261884e-01 5.889944e-05 0 12 FALSE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8075593 0.6554240 U 0.4686274 0.6162291 13773 129 184239 184240 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.291991 2.706677 0.9534978 2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold R conserved hypothetical protein 1.225556 2.574828 0.9671999 - - - paREP4 0.000000e+00 0 4.413630e-03 3.599895e-02 5.066423e-01 9.563502e-01 1.531974e-03 12 0 TRUE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8128897 0.6509568 U 0.4686274 0.6162291 13773 129 184240 184241 1 84 Divergent - + 0.000000 0 0.000000 0.00000000 1.225556 2.574828 0.9671999 - - - paREP4 1.302983 3.136687 1.1831902 - - - hypothetical protein 0.000000e+00 0 5.995008e-03 3.351648e-02 3.390344e-01 9.372079e-01 3.402032e-03 0 0 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8090097 0.6479144 U 0.4686274 0.6162291 13773 129 184241 184242 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.302983 3.136687 1.1831902 - - - hypothetical protein 1.581845 3.549597 1.1261322 - - - possible heat shock protein, htpX homolog part 1, authentic frameshift 0.000000e+00 0 7.776397e-02 -1.936037e-02 -2.183464e-01 -7.800453e-01 3.132058e+00 0 0 FALSE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3839157 0.4007062 U 0.4686274 0.6162291 13773 129 184242 184243 1 -88 Same + + 0.000000 0 0.000000 0.00000000 1.581845 3.549597 1.1261322 - - - possible heat shock protein, htpX homolog part 1, authentic frameshift 1.268375 2.925977 0.9623850 501 Zn-dependent protease with chaperone function O possible heat shock protein, htpX homolog part 2, authentic frameshift 0.000000e+00 0 9.826318e-02 -2.387501e-02 -2.165704e-01 -8.138218e-01 3.277684e+00 0 1 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3822468 0.4001595 U 0.4686274 0.6162291 13773 129 184243 184244 1 301 Same + + 0.000000 0 0.000000 0.00000000 1.268375 2.925977 0.9623850 501 Zn-dependent protease with chaperone function O possible heat shock protein, htpX homolog part 2, authentic frameshift 1.406811 3.130187 1.0351043 1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes I hypothetical protein 0.000000e+00 0 1.916451e-02 8.159211e-03 3.612288e-02 3.339528e-01 4.086967e-01 0 1 0 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6060641 0.5107204 N 0.5492530 0.6245624 13773 129 184244 184245 1 -9 Convergent + - 0.000000 0 0.000000 0.00000000 1.406811 3.130187 1.0351043 1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes I hypothetical protein 1.579262 3.579866 1.1566054 - - - hypothetical protein 0.000000e+00 0 2.973912e-02 -5.700591e-03 -9.440504e-03 -2.808655e-01 1.357234e+00 0 0 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4450675 0.4220582 U 0.4686274 0.6162291 13773 129 184245 184246 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.579262 3.579866 1.1566054 - - - hypothetical protein 1.591928 3.550915 1.1348918 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R ATP-dependant helicase, probable 0.000000e+00 0 1.604339e-04 1.797004e-02 2.394819e-01 7.021638e-01 7.633367e-04 0 0 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7523075 0.6522016 U 0.4686274 0.6162291 13773 129 184246 184247 1 180 Same - - 0.000000 0 0.000000 0.00000000 1.591928 3.550915 1.1348918 1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster R ATP-dependant helicase, probable 1.569285 3.460295 1.1003848 1194 A/G-specific DNA glycosylase L U/G & T/G mismatch specific glycosylase (Pa-MIG) 0.000000e+00 0 5.127123e-04 1.656793e-02 1.995944e-01 6.832041e-01 2.488501e-03 0 4 TRUE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7478892 0.6493745 U 0.4686274 0.6162291 13773 129 184247 184248 1 41 Divergent - + 0.000000 0 0.000000 0.00000000 1.569285 3.460295 1.1003848 1194 A/G-specific DNA glycosylase L U/G & T/G mismatch specific glycosylase (Pa-MIG) 1.666672 3.662900 1.0837883 - - - conserved protein 7.562104e-04 1 9.484317e-03 2.537968e-02 3.998827e-01 7.601415e-01 2.126270e-02 4 1 TRUE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4649491 0.7708079 0.6369786 U 0.4686274 0.6162291 13773 129 184248 184249 1 -9 Convergent + - 2.079442 0 2.079442 2.07944154 1.666672 3.662900 1.0837883 - - - conserved protein 1.485343 3.215848 1.0901599 270 Site-specific DNA methylase L C-5 cytosine-specific DNA methylase 7.158483e-02 1 3.288009e-02 7.308866e-03 -8.571857e-03 3.891633e-01 2.886073e-01 1 1 FALSE FALSE 119 FALSE 2.9335626 1.6614134 0.5480306 2.9479804 0.6329203 0.9205230 0.6300024 0.5474398 U 0.4686274 0.8396881 13773 129 184249 184250 1 463 Divergent - + 0.000000 0 0.000000 0.00000000 1.485343 3.215848 1.0901599 270 Site-specific DNA methylase L C-5 cytosine-specific DNA methylase 1.339755 2.919897 0.9677810 - - - hypothetical protein 0.000000e+00 0 2.119598e-02 -3.790172e-03 5.144675e-03 -3.422116e-01 1.547666e+00 1 0 TRUE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4292359 0.4156630 U 0.4686274 0.6162291 13773 129 184250 184251 1 121 Same + + 0.000000 0 0.000000 0.00000000 1.339755 2.919897 0.9677810 - - - hypothetical protein 1.452452 3.144079 1.0770866 675 Transposase and inactivated derivatives L hypothetical protein 0.000000e+00 0 1.270066e-02 -1.182732e-04 -1.229223e-02 -9.019036e-02 8.867482e-01 0 0 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4951475 0.4480717 U 0.4686274 0.6162291 13773 129 184251 184252 1 -13 Same + + 0.000000 0 0.000000 0.00000000 1.452452 3.144079 1.0770866 675 Transposase and inactivated derivatives L hypothetical protein 1.314740 3.010477 1.0018399 433 Predicted ATPase R hypothetical protein 0.000000e+00 0 1.896458e-02 -1.447747e-04 6.646464e-02 -9.832908e-02 1.034053e+00 0 0 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4920561 0.4366685 U 0.4686274 0.6162291 13773 129 184252 184253 1 -25 Same + + 0.000000 0 0.000000 0.00000000 1.314740 3.010477 1.0018399 433 Predicted ATPase R hypothetical protein 1.331367 3.121290 1.0162919 - - - hypothetical protein 0.000000e+00 0 2.764338e-04 1.640188e-02 2.016754e-01 7.866327e-01 1.847086e-03 0 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7809774 0.6505622 U 0.4686274 0.6162291 13773 129 184253 184254 1 50 Same + + 0.000000 0 0.000000 0.00000000 1.331367 3.121290 1.0162919 - - - hypothetical protein 1.443733 3.064275 1.0280045 - - - paREP8 0.000000e+00 0 1.262627e-02 9.193442e-04 -4.948989e-03 -2.059596e-02 7.911850e-01 0 0 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5151498 0.4567559 U 0.4686274 0.6162291 13773 129 184254 184255 1 123 Same + + 0.000000 0 0.000000 0.00000000 1.443733 3.064275 1.0280045 - - - paREP8 1.315532 2.908415 1.0229206 - - - paREP8 0.000000e+00 0 1.643557e-02 1.040630e-03 7.963070e-02 -2.154542e-02 8.637727e-01 0 0 FALSE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5146731 0.4489519 U 0.4686274 0.6162291 13773 129 184255 184256 1 332 Same + + 0.000000 0 0.000000 0.00000000 1.315532 2.908415 1.0229206 - - - paREP8 1.449023 3.182522 1.1040472 1396 Predicted transcriptional regulators K helix-turn-helix protein 0.000000e+00 0 1.781994e-02 3.219154e-04 -2.235879e-02 -6.741630e-02 9.604903e-01 0 1 FALSE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5015939 0.4421694 U 0.4686274 0.6162291 13773 129 184256 184257 1 -3 Same + + 2.662588 0 2.662588 2.66258783 1.449023 3.182522 1.1040472 1396 Predicted transcriptional regulators K helix-turn-helix protein 1.401844 3.543728 1.1875777 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 3.279005e-02 1 2.225920e-03 1.174041e-04 2.833094e-02 -2.970888e-02 2.242237e-01 1 7 FALSE FALSE 125 TRUE 2.9244472 1.7076796 0.5480306 2.9399224 0.6329203 0.7581838 0.5120718 0.5729102 U 0.4686274 0.8476113 13773 129 184257 184258 1 8 Convergent + - 0.000000 0 0.000000 0.00000000 1.401844 3.543728 1.1875777 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved hypothetical protein 1.289003 2.531850 1.1098962 - - - hypothetical protein 0.000000e+00 0 1.273297e-02 8.046257e-03 1.755498e-01 3.859091e-01 3.225333e-01 7 0 FALSE FALSE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6282261 0.5340554 U 0.4686274 0.6162291 13773 129 184258 184259 1 90 Divergent - + 0.000000 0 0.000000 0.00000000 1.289003 2.531850 1.1098962 - - - hypothetical protein 1.427164 3.123311 1.0689463 1408 Predicted phosphohydrolases R conserved hypothetical protein 0.000000e+00 0 1.908850e-02 3.934443e-03 1.263254e-03 1.432317e-01 6.705636e-01 0 9 TRUE FALSE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5284194 0.4684793 U 0.4686274 0.6162291 13773 129 184259 184260 1 35 Same + + 0.000000 0 0.000000 0.00000000 1.427164 3.123311 1.0689463 1408 Predicted phosphohydrolases R conserved hypothetical protein 1.579449 3.543673 1.1011201 2430 Uncharacterized conserved protein S conserved hypothetical protein 7.220042e-03 4 2.319063e-02 -3.102602e-03 2.461438e-02 -1.223153e-01 9.484936e-01 9 4 FALSE FALSE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.5709489 0.4843873 0.4427224 U 0.4686274 0.6162291 13773 129 184260 184261 1 4 Same + + 6.788972 0 8.986196 8.98619632 1.579449 3.543673 1.1011201 2430 Uncharacterized conserved protein S conserved hypothetical protein 1.575039 3.587653 1.1515095 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 8.869744e-02 4 1.944811e-05 1.583368e-02 2.030507e-01 6.730510e-01 1.154429e-04 4 16 FALSE FALSE 127 TRUE 2.7603339 1.8272121 0.5480306 2.7859285 0.7323301 0.9756975 0.7443823 0.6549470 U 0.4686274 0.8685996 13773 129 184261 184262 1 492 Convergent + - 0.000000 0 0.000000 -0.25131443 1.575039 3.587653 1.1515095 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 1.422781 3.111566 1.0714167 116 Predicted N6-adenine-specific DNA methylase L conserved hypothetical protein 6.289505e-03 5 2.318249e-02 -3.537729e-03 -5.737256e-02 -1.595056e-01 1.021604e+00 0 16 5 FALSE FALSE 128 FALSE 0.4469764 0.2639739 0.5480306 0.4469764 0.7448207 0.5613206 0.4743375 0.4378021 N 0.5492530 0.5545514 13773 129 184262 184263 1 60 Divergent - + 0.000000 0 0.000000 -0.43227637 1.422781 3.111566 1.0714167 116 Predicted N6-adenine-specific DNA methylase L conserved hypothetical protein 1.390970 3.087344 1.0966105 1855 ATPase (PilT family) R conserved hypothetical protein 8.674503e-02 5 1.011968e-03 1.728808e-03 4.814411e-02 9.717524e-02 9.050724e-02 5 10 TRUE FALSE 127 FALSE 0.4469764 0.2388166 0.5480306 0.4469764 0.7448207 0.9589571 0.5182994 0.6107212 U 0.4686274 0.5378371 13773 129 184263 184264 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.390970 3.087344 1.0966105 1855 ATPase (PilT family) R conserved hypothetical protein 1.422925 3.197382 1.0858670 500 SAM-dependent methyltransferases QR conserved hypothetical protein 6.018027e-03 3 1.021172e-03 1.720086e-03 3.363578e-02 9.679416e-02 9.096960e-02 10 3 FALSE FALSE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7136133 0.5568314 0.5182191 0.6104368 U 0.4686274 0.6162291 13773 129 184264 184265 1 -10 Convergent + - 0.000000 0 0.000000 -0.31575091 1.422925 3.197382 1.0858670 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.429564 3.215262 1.1032080 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R conserved hypothetical protein 2.566662e-02 3 4.406590e-05 6.214177e-04 2.715559e-02 2.393673e-02 5.204355e-03 3 40 FALSE FALSE 129 FALSE 0.4469764 0.2514250 0.5480306 0.4469764 0.7136133 0.7147639 0.5174088 0.6462385 U 0.4686274 0.5418278 13773 129 184265 184266 1 4 Same - - 0.000000 0 0.000000 0.00000000 1.429564 3.215262 1.1032080 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R conserved hypothetical protein 1.557068 3.290218 1.0890557 - - - paREP2b 0.000000e+00 0 1.625731e-02 -2.306795e-03 2.091513e-02 -9.405063e-02 7.898203e-01 40 0 TRUE FALSE 128 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4941157 0.4568835 U 0.4686274 0.6162291 13773 129 184266 184267 1 40 Same - - 0.000000 0 0.000000 0.00000000 1.557068 3.290218 1.0890557 - - - paREP2b 1.818023 4.007245 1.2029166 - - - paREP2b 0.000000e+00 0 6.809780e-02 3.874370e-02 7.867363e-01 7.606344e-01 5.160533e-02 0 0 TRUE FALSE 127 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7712666 0.6233610 U 0.4686274 0.6162291 13773 129 184267 184268 1 57 Same - - 0.000000 0 0.000000 0.00000000 1.818023 4.007245 1.2029166 - - - paREP2b 1.408775 3.191657 1.0823122 30 Dimethyladenosine transferase (rRNA methylation) J dimethyladenosine transferase 0.000000e+00 0 1.674845e-01 -1.562509e-02 -4.986984e-01 -3.223932e-01 1.736408e+00 0 14 TRUE FALSE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4349384 0.4117409 U 0.4686274 0.6162291 13773 129 184268 184269 1 33 Divergent - + 0.000000 0 0.000000 -0.11778304 1.408775 3.191657 1.0823122 30 Dimethyladenosine transferase (rRNA methylation) J dimethyladenosine transferase 1.369707 2.976300 1.0636306 2511 Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) J Glu-tRNA(Gln) amidotransferase subunit B (gatB) 8.277205e-03 12 1.526275e-03 3.481286e-03 7.377434e-02 2.140152e-01 1.119655e-01 J 14 12 TRUE FALSE 125 FALSE 0.4469764 0.2945188 0.5480306 0.4469764 0.7776747 0.5822313 0.5548426 0.6025456 Y 1.4497162 0.6577314 13773 129 184269 184270 1 221 Same + + 0.000000 0 0.000000 -0.31285006 1.369707 2.976300 1.0636306 2511 Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) J Glu-tRNA(Gln) amidotransferase subunit B (gatB) 1.550109 3.384570 1.1454055 2174 Ribosomal protein L34E J ribosomal protein L34 1.689996e-01 6 3.254489e-02 -8.063712e-03 -6.574316e-02 -4.892500e-01 1.963870e+00 J 12 6 FALSE FALSE 126 TRUE 0.4469764 0.2537346 0.5480306 0.4469764 0.7537284 1.1107342 0.4066353 0.4085563 Y 1.4497162 0.6459393 13773 129 184270 184271 1 6 Same + + 15.747322 0 18.409910 18.40990961 1.550109 3.384570 1.1454055 2174 Ribosomal protein L34E J ribosomal protein L34 1.531463 3.455825 1.1313152 1102 Cytidylate kinase F cytidylate kinase (cmk) 1.449806e-01 6 3.476887e-04 7.904216e-03 1.046900e-01 5.097540e-01 3.053347e-03 0 6 15 FALSE FALSE 127 TRUE 2.5422285 1.9048547 0.5480306 2.6264658 0.7537284 1.0836851 0.6767763 0.6486369 N 0.5492530 0.8859462 13773 129 184271 184272 1 54 Same + + 0.000000 0 0.000000 -0.19068981 1.531463 3.455825 1.1313152 1102 Cytidylate kinase F cytidylate kinase (cmk) 1.389190 3.001499 1.0577135 493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases ER glutamate synthase small subunit gltD 1.265355e-02 4 2.024162e-02 -4.980599e-03 -4.395224e-02 -3.479190e-01 1.424203e+00 15 4 FALSE FALSE 128 TRUE 0.4469764 0.2733593 0.5480306 0.4469764 0.7323301 0.6206531 0.4284314 0.4192722 U 0.4686274 0.5487570 13773 129 184272 184273 1 1 Convergent + - 0.000000 0 0.000000 -0.19068981 1.389190 3.001499 1.0577135 493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases ER glutamate synthase small subunit gltD 1.422372 2.968446 1.0133451 1889 Fibrillarin-like rRNA methylase J fibrillarin-like pre-rRNA processing protein (flpA) 1.782262e-02 4 1.101065e-03 1.805183e-03 3.415725e-02 1.014602e-01 9.376850e-02 4 12 FALSE FALSE 129 FALSE 0.4469764 0.2733593 0.5480306 0.4469764 0.7323301 0.6602470 0.5189674 0.6094409 U 0.4686274 0.5487570 13773 129 184273 184274 1 228 Same - - 17.903724 0 26.172931 26.17293092 1.422372 2.968446 1.0133451 1889 Fibrillarin-like rRNA methylase J fibrillarin-like pre-rRNA processing protein (flpA) 1.400475 3.106283 1.0811587 1498 Protein implicated in ribosomal biogenesis, Nop56p homolog J nop family pre-rRNA processing protein 2.029016e-01 7 4.794996e-04 1.477688e-03 4.246055e-02 8.316660e-02 4.617716e-02 J 12 7 TRUE FALSE 128 TRUE 2.4985447 1.9488255 0.5480306 2.5004783 0.7596462 1.1426046 0.5176948 0.6255200 Y 1.4497162 0.9246054 13773 129 184274 184275 1 585 Divergent - + 0.000000 0 0.000000 0.00000000 1.400475 3.106283 1.0811587 1498 Protein implicated in ribosomal biogenesis, Nop56p homolog J nop family pre-rRNA processing protein 1.520513 3.475730 1.1155995 - - - paREP1 0.000000e+00 0 1.440920e-02 -3.519473e-03 -1.486438e-02 -2.600151e-01 1.084603e+00 7 0 TRUE FALSE 127 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4503522 0.4341358 U 0.4686274 0.6162291 13773 129 184275 184276 1 28 Convergent + - 0.000000 0 0.000000 0.00000000 1.520513 3.475730 1.1155995 - - - paREP1 1.431418 3.113628 1.0966771 1680 Beta-lactamase class C and other penicillin binding proteins V beta-lactamase-like protein 0.000000e+00 0 7.937856e-03 -1.380645e-03 -6.524684e-03 -6.199991e-02 5.259867e-01 0 12 FALSE FALSE 128 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5033352 0.4884610 U 0.4686274 0.6162291 13773 129 184276 184277 1 3 Same - - 0.000000 0 0.000000 0.00000000 1.431418 3.113628 1.0966771 1680 Beta-lactamase class C and other penicillin binding proteins V beta-lactamase-like protein 1.397059 2.970651 1.0415748 468 RecA/RadA recombinase L DNA repair protein radA 0.000000e+00 0 1.180541e-03 1.085291e-03 3.991098e-02 4.460042e-02 1.235498e-01 0 12 0 TRUE FALSE 127 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5185203 0.5998031 N 0.5492530 0.6245624 13773 129 184277 184278 1 21 Same - - 0.000000 0 0.000000 0.00000000 1.397059 2.970651 1.0415748 468 RecA/RadA recombinase L DNA repair protein radA 1.539564 3.471661 1.1301969 - - - hypothetical protein 0.000000e+00 0 2.030771e-02 -4.790676e-03 -2.303052e-02 -3.205007e-01 1.350091e+00 0 0 TRUE FALSE 126 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4353229 0.4223570 U 0.4686274 0.6162291 13773 129 184278 184279 1 151 Divergent - + 0.000000 0 0.000000 0.00000000 1.539564 3.471661 1.1301969 - - - hypothetical protein 1.494636 3.193502 1.0705636 - - - hypothetical protein 0.000000e+00 0 2.018561e-03 3.812815e-03 5.032429e-02 3.352427e-01 5.770319e-02 0 0 TRUE FALSE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6071342 0.6211938 U 0.4686274 0.6162291 13773 129 184279 184280 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.494636 3.193502 1.0705636 - - - hypothetical protein 1.388319 3.216019 1.0643878 3432 Predicted transcriptional regulator K conserved hypothetical protein 0.000000e+00 0 1.130330e-02 -2.727512e-03 -5.798989e-03 -2.423005e-01 9.710492e-01 0 0 FALSE FALSE 126 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4532947 0.4416178 U 0.4686274 0.6162291 13773 129 184280 184281 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.388319 3.216019 1.0643878 3432 Predicted transcriptional regulator K conserved hypothetical protein 1.418570 3.264204 1.1012242 - - - hypothetical protein 0.000000e+00 0 9.151334e-04 2.070253e-03 3.757660e-02 1.191771e-01 7.976398e-02 0 0 TRUE FALSE 125 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5218559 0.6145887 U 0.4686274 0.6162291 13773 129 184281 184282 1 173 Divergent - + 0.000000 0 0.000000 0.00000000 1.418570 3.264204 1.1012242 - - - hypothetical protein 1.356040 3.031479 1.0524729 1192 ATPases involved in chromosome partitioning D chromosome partitioning ATPase, parA family protein, conjectural 0.000000e+00 0 3.909977e-03 3.129724e-03 7.768488e-02 1.728958e-01 2.643996e-01 0 7 TRUE FALSE 124 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5393239 0.5555494 U 0.4686274 0.6162291 13773 129 184282 184283 1 143 Convergent + - 0.000000 0 0.000000 0.00000000 1.356040 3.031479 1.0524729 1192 ATPases involved in chromosome partitioning D chromosome partitioning ATPase, parA family protein, conjectural 1.484735 3.159861 1.0512125 - - - conserved within P. aerophilum 0.000000e+00 0 1.656227e-02 -3.179241e-03 -3.670121e-02 -3.034264e-01 1.328774e+00 7 0 FALSE FALSE 125 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4394742 0.4230623 U 0.4686274 0.6162291 13773 129 184283 184284 1 41 Same - - 0.000000 0 0.000000 0.00000000 1.484735 3.159861 1.0512125 - - - conserved within P. aerophilum 1.404632 2.995427 1.0251844 1247 Sortase and related acyltransferases M conserved hypothetical protein 0.000000e+00 0 6.416523e-03 -1.559112e-03 5.237895e-03 -1.492158e-01 5.984560e-01 0 1 TRUE FALSE 124 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4767755 0.4769309 U 0.4686274 0.6162291 13773 129 184284 184285 1 -19 Same - - 0.000000 0 0.000000 -0.13353139 1.404632 2.995427 1.0251844 1247 Sortase and related acyltransferases M conserved hypothetical protein 1.417181 2.992076 1.0391802 656 Aldo/keto reductases, related to diketogulonate reductase R morphine 6-dehydrogenase, conjectural 8.054069e-03 1 1.574825e-04 1.599795e-03 3.686242e-02 8.924797e-02 1.526732e-02 1 41 TRUE FALSE 123 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.5809077 0.5177716 0.6402042 U 0.4686274 0.5517368 13773 129 184285 184286 1 30 Same - - 0.000000 0 0.000000 -0.18221272 1.417181 2.992076 1.0391802 656 Aldo/keto reductases, related to diketogulonate reductase R morphine 6-dehydrogenase, conjectural 1.448336 3.019726 1.0771493 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein 4.170005e-03 3 9.706262e-04 1.045908e-04 1.901193e-02 -1.624388e-02 9.613331e-02 41 3 TRUE FALSE 122 TRUE 0.4469764 0.2749489 0.5480306 0.4469764 0.7136133 0.5381027 0.5167496 0.6083676 U 0.4686274 0.5492585 13773 129 184286 184287 1 -3 Same - - 2.793208 0 2.793208 2.47183377 1.448336 3.019726 1.0771493 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein 1.462228 3.184359 1.1055444 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein 1.241845e-01 3 1.929909e-04 -3.312401e-05 2.062479e-02 1.347678e-02 1.824469e-02 C 3 5 TRUE FALSE 121 TRUE 2.9180123 1.6867846 0.5480306 2.9337967 0.7136133 1.0563233 0.5183810 0.6385209 Y 1.4497162 0.8929041 13773 129 184287 184288 1 79 Divergent - + 0.000000 0 0.000000 0.00000000 1.462228 3.184359 1.1055444 1042 Acyl-CoA synthetase (NDP forming) C conserved hypothetical protein 1.464953 3.252179 1.0944779 - - - hypothetical protein 0.000000e+00 0 7.427215e-06 1.469253e-04 2.262442e-02 4.430298e-02 3.115780e-04 5 0 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184846 0.6539188 U 0.4686274 0.6162291 13773 129 184288 184289 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.464953 3.252179 1.0944779 - - - hypothetical protein 1.438843 3.205899 1.0909442 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 0.000000e+00 0 6.817217e-04 -1.701750e-04 1.868094e-02 -6.064286e-03 6.106930e-02 0 1 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195057 0.6200599 U 0.4686274 0.6162291 13773 129 184289 184290 1 102 Divergent - + 0.000000 0 0.000000 0.00000000 1.438843 3.205899 1.0909442 668 Small-conductance mechanosensitive channel M conserved hypothetical protein 1.459276 3.177424 1.0556032 370 Fe2+ transport system protein B P conserved within P. aerophilum 0.000000e+00 0 4.174814e-04 -9.892583e-05 1.933888e-02 -4.770855e-03 4.012289e-02 0 1 0 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197094 0.6279101 N 0.5492530 0.6245624 13773 129 184290 184291 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.459276 3.177424 1.0556032 370 Fe2+ transport system protein B P conserved within P. aerophilum 1.513814 3.436301 1.1659767 - - - conserved within P. aerophilum 0.000000e+00 0 2.974423e-03 4.920551e-04 3.622806e-02 1.011156e-01 1.704809e-01 0 0 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5188834 0.5875676 U 0.4686274 0.6162291 13773 129 184291 184292 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.513814 3.436301 1.1659767 - - - conserved within P. aerophilum 1.611208 3.345415 1.0872249 1552 Ribosomal protein L40E J ribosomal protein L40 0.000000e+00 0 9.485584e-03 9.975832e-03 1.923442e-01 5.190602e-01 9.050724e-02 0 3 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6840706 0.6107212 U 0.4686274 0.6162291 13773 129 184292 184293 1 190 Convergent + - 0.000000 0 0.000000 -0.26504093 1.611208 3.345415 1.0872249 1552 Ribosomal protein L40E J ribosomal protein L40 1.442284 3.036951 1.0498839 648 Endonuclease IV L DNA-(apurinic or apyrimidinic site) lyase (endonuclease IV) 7.475750e-02 3 2.853527e-02 -1.455720e-03 -6.093353e-02 8.843751e-03 7.681453e-01 0 3 13 FALSE FALSE 121 FALSE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.9356931 0.5189848 0.4580319 N 0.5492530 0.5534886 13773 129 184293 184294 1 175 Divergent - + 0.000000 0 0.000000 -0.62387718 1.442284 3.036951 1.0498839 648 Endonuclease IV L DNA-(apurinic or apyrimidinic site) lyase (endonuclease IV) 1.444164 3.136019 1.0952778 1293 Predicted RNA-binding protein homologous to eukaryotic snRNP K conserved hypothetical protein 9.959272e-02 11 3.534738e-06 6.584455e-05 2.142956e-02 2.756494e-04 3.115780e-04 0 13 11 TRUE FALSE 120 FALSE 0.4469764 0.2300613 0.5480306 0.4469764 0.7764261 1.0128743 0.5199424 0.6539188 N 0.5492530 0.5438543 13773 129 184294 184295 1 57 Convergent + - 0.000000 0 0.000000 0.00000000 1.444164 3.136019 1.0952778 1293 Predicted RNA-binding protein homologous to eukaryotic snRNP K conserved hypothetical protein 1.446520 3.874333 1.2732371 - - - P. aerophilum family 550 protein 0.000000e+00 0 5.551354e-06 3.522222e-05 2.107711e-02 1.314636e-03 3.981602e-04 11 0 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198704 0.6536323 U 0.4686274 0.6162291 13773 129 184295 184296 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.446520 3.874333 1.2732371 - - - P. aerophilum family 550 protein 1.532651 3.426925 1.1361260 - - - P. aerophilum family 66 protein 0.000000e+00 0 7.418458e-03 -3.959340e-04 3.281602e-02 3.279285e-02 4.116458e-01 0 0 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5174668 0.5103693 U 0.4686274 0.6162291 13773 129 184296 184297 1 48 Divergent - + 0.000000 0 0.000000 0.00000000 1.532651 3.426925 1.1361260 - - - P. aerophilum family 66 protein 1.464706 3.160688 1.0265853 1656 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 4.616548e-03 1.081765e-03 1.706807e-02 1.502124e-01 2.220485e-01 0 6 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5304007 0.5735582 U 0.4686274 0.6162291 13773 129 184297 184298 1 -28 Convergent + - 0.000000 0 0.000000 0.00000000 1.464706 3.160688 1.0265853 1656 Uncharacterized conserved protein S conserved hypothetical protein 1.567695 3.651362 1.1671435 167 Dihydroorotate dehydrogenase F dihydroorotate dehydrogenase (pyrD) 8.421529e-03 6 1.060685e-02 1.548301e-03 7.274076e-02 1.739654e-01 3.366315e-01 6 7 FALSE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7537284 0.5835606 0.5396104 0.5289643 U 0.4686274 0.6162291 13773 129 184298 184299 1 -12 Same - - 0.000000 0 0.000000 -0.85121176 1.567695 3.651362 1.1671435 167 Dihydroorotate dehydrogenase F dihydroorotate dehydrogenase (pyrD) 1.431834 3.100394 1.0712098 461 Orotate phosphoribosyltransferase F orotate phosphoribosyltransferase (pyrE) 4.766698e-03 7 1.845828e-02 -2.274750e-03 -3.923780e-02 -7.411906e-02 7.939179e-01 F 7 42 TRUE FALSE 119 TRUE 0.4469764 0.2174351 0.5480306 0.4469764 0.7596462 0.5426548 0.5000893 0.4559908 Y 1.4497162 0.6352919 13773 129 184299 184300 1 12 Same - - 5.495528 0 8.158115 5.21908675 1.431834 3.100394 1.0712098 461 Orotate phosphoribosyltransferase F orotate phosphoribosyltransferase (pyrE) 1.454427 3.163052 1.0445590 1781 Aspartate carbamoyltransferase, regulatory subunit F aspartate carbamoyltransferase, regulatory subunit (pyrI) 7.652572e-02 18 5.104353e-04 -5.933936e-05 1.909576e-02 -1.168800e-02 4.784107e-02 F 42 18 TRUE FALSE 118 TRUE 2.7996416 1.7715703 0.5480306 2.8030968 0.7781393 0.9399550 0.5180885 0.6247981 Y 1.4497162 0.9040847 13773 129 184300 184301 1 499 Same - - 0.000000 0 0.000000 -0.07410797 1.454427 3.163052 1.0445590 1781 Aspartate carbamoyltransferase, regulatory subunit F aspartate carbamoyltransferase, regulatory subunit (pyrI) 1.383407 3.053369 1.0615078 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein, putative -9.899478e-03 4 5.043777e-03 -2.062600e-04 3.004041e-02 -7.022462e-02 4.675915e-01 0 18 4 TRUE FALSE 117 TRUE 0.4469764 0.2976889 0.5480306 0.4469764 0.7323301 0.5247453 0.5013484 0.4996268 N 0.5492530 0.5651364 13773 129 184301 184302 1 70 Divergent - + 1.992430 0 1.992430 1.99243016 1.383407 3.053369 1.0615078 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein, putative 1.408581 3.166510 1.0918918 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid ABC transporter, ATP-binding protein, putative 9.711641e-03 4 6.337298e-04 2.910581e-03 4.768580e-02 1.824127e-01 5.336348e-02 E 4 5 TRUE FALSE 116 FALSE 2.9329858 1.6530229 0.5480306 2.9471180 0.7323301 0.5948613 0.5429729 0.6227021 Y 1.4497162 0.8885368 13773 129 184302 184303 1 162 Convergent + - 0.000000 0 0.000000 0.00000000 1.408581 3.166510 1.0918918 410 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid ABC transporter, ATP-binding protein, putative 1.383895 3.106586 1.0375652 1758 DNA-directed RNA polymerase, subunit K/omega K DNA-directed RNA polymerase subunit 0.000000e+00 0 6.093828e-04 2.889676e-03 6.143981e-02 1.821618e-01 5.300950e-02 0 5 0 FALSE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5426754 0.6228520 N 0.5492530 0.6245624 13773 129 184303 184304 1 78 Same - - 0.000000 0 0.000000 0.00000000 1.383895 3.106586 1.0375652 1758 DNA-directed RNA polymerase, subunit K/omega K DNA-directed RNA polymerase subunit 1.399065 3.017083 1.0554111 459 Chaperonin GroEL (HSP60 family) O thermosome (chaperonin) beta subunit 0.000000e+00 0 2.301197e-04 3.531980e-03 5.741850e-02 2.398892e-01 1.603537e-02 0 0 7 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5646332 0.6397376 N 0.5492530 0.6245624 13773 129 184304 184305 1 46 Same - - 0.000000 0 0.000000 -0.13150953 1.399065 3.017083 1.0554111 459 Chaperonin GroEL (HSP60 family) O thermosome (chaperonin) beta subunit 1.478679 3.290592 1.0722279 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-ketoacid ferredoxin oxidoreductase beta subunit 3.216415e-02 4 6.338416e-03 -1.427839e-03 -1.019851e-03 -1.529872e-01 6.176054e-01 0 7 4 TRUE FALSE 115 TRUE 0.4469764 0.2892175 0.5480306 0.4469764 0.7323301 0.7489643 0.4760116 0.4750470 N 0.5492530 0.5624819 13773 129 184305 184306 1 -3 Same - - 4.859812 0 4.859812 4.80062353 1.478679 3.290592 1.0722279 1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit C 2-ketoacid ferredoxin oxidoreductase beta subunit 1.475306 3.177926 1.0943908 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-ketoacid ferredoxin oxidoreductase alpha subunit 1.090583e-01 4 1.138178e-05 6.524970e-04 2.792822e-02 1.142631e-01 1.140293e-03 C 4 4 TRUE FALSE 114 TRUE 2.8416702 1.7598186 0.5480306 2.8954298 0.7323301 1.0429031 0.5208098 0.6516922 Y 1.4497162 0.9023201 13773 129 184306 184307 1 -3 Same - - 2.197225 0 2.197225 2.13803571 1.475306 3.177926 1.0943908 674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit C 2-ketoacid ferredoxin oxidoreductase alpha subunit 1.371909 2.954969 1.0472439 1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit C 2-ketoacid ferredoxin oxidoreductase delta subunit 8.678342e-02 2 1.069088e-02 -1.900684e-03 1.310605e-02 -2.073025e-01 9.336038e-01 C 4 2 TRUE FALSE 113 TRUE 2.9321590 1.6679624 0.5480306 2.9469979 0.6838149 0.9642105 0.4623560 0.4442659 Y 1.4497162 0.8904181 13773 129 184307 184308 1 147 Divergent - + 0.000000 0 0.000000 0.00000000 1.371909 2.954969 1.0472439 1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit C 2-ketoacid ferredoxin oxidoreductase delta subunit 1.507357 3.312188 1.1221701 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C 2-ketoacid ferredoxin oxidoreductase gamma subunit 3.728161e-04 1 1.834622e-02 -4.448262e-03 -3.936271e-02 -3.557291e-01 1.431540e+00 C 2 1 TRUE FALSE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.4270132 0.4189018 Y 1.4497162 0.7118045 13773 129 184308 184309 1 -3 Convergent + - 0.000000 0 0.000000 -0.12516314 1.507357 3.312188 1.1221701 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C 2-ketoacid ferredoxin oxidoreductase gamma subunit 1.436544 3.184358 1.0850191 677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase M UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural 5.899547e-03 1 5.014515e-03 -8.310104e-04 3.627470e-03 -2.625619e-02 3.592636e-01 0 1 48 FALSE FALSE 113 FALSE 0.4469764 0.2919799 0.5480306 0.4469764 0.6329203 0.5540132 0.5133304 0.5214465 N 0.5492530 0.5633479 13773 129 184309 184310 1 46 Divergent - + 0.000000 0 0.000000 -2.60827448 1.436544 3.184358 1.0850191 677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase M UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase, conjectural 1.549488 3.372190 1.1218462 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R conserved hypothetical protein 6.409358e-02 10 1.275635e-02 -1.456607e-03 2.758347e-02 -3.520302e-02 6.200203e-01 48 10 TRUE FALSE 112 FALSE 0.4469764 0.1936804 0.5480306 0.4469764 0.7739415 0.9048018 0.5106205 0.4746158 U 0.4686274 0.5235150 13773 129 184310 184311 1 81 Same + + 0.000000 0 0.000000 0.00000000 1.549488 3.372190 1.1218462 1234 Metal-dependent hydrolases of the beta-lactamase superfamily III R conserved hypothetical protein 1.480889 3.112515 1.0495184 1909 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.976326e-03 1 4.705778e-03 2.893450e-03 3.234140e-02 2.753784e-01 1.351395e-01 10 1 FALSE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4947521 0.5828152 0.5970160 U 0.4686274 0.6162291 13773 129 184311 184312 1 24 Same + + 0.000000 0 0.000000 0.00000000 1.480889 3.112515 1.0495184 1909 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.450067 3.330376 1.0663381 1651 Protein-disulfide isomerase O hypothetical protein 0.000000e+00 0 9.499847e-04 -3.909548e-05 1.807557e-02 3.113719e-02 8.326967e-02 1 0 FALSE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173982 0.6130924 U 0.4686274 0.6162291 13773 129 184312 184313 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.450067 3.330376 1.0663381 1651 Protein-disulfide isomerase O hypothetical protein 1.436011 3.183956 1.0739055 - - - hypothetical protein 0.000000e+00 0 1.975956e-04 2.038821e-05 2.157250e-02 -4.301426e-03 1.824469e-02 0 0 FALSE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197773 0.6385209 U 0.4686274 0.6162291 13773 129 184313 184314 1 148 Divergent - + 0.000000 0 0.000000 0.00000000 1.436011 3.183956 1.0739055 - - - hypothetical protein 1.630002 3.400240 1.0884542 1537 Predicted RNA-binding proteins R cell division protein pelota (pelA), conjectural 0.000000e+00 0 3.763265e-02 -2.747419e-03 6.902659e-02 -4.688160e-02 9.276809e-01 0 12 TRUE FALSE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5073268 0.4451969 U 0.4686274 0.6162291 13773 129 184314 184315 1 35 Convergent + - 0.000000 0 0.000000 0.00000000 1.630002 3.400240 1.0884542 1537 Predicted RNA-binding proteins R cell division protein pelota (pelA), conjectural 1.236591 2.598014 0.9637321 - - - paREP4 0.000000e+00 0 1.547718e-01 -3.836548e-02 -3.916836e-01 -9.054446e-01 3.628396e+00 12 0 FALSE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3786551 0.3992015 U 0.4686274 0.6162291 13773 129 184315 184316 1 246 Divergent - + 0.000000 0 0.000000 0.00000000 1.236591 2.598014 0.9637321 - - - paREP4 1.602759 3.491458 1.1034950 - - - conserved within P. aerophilum 0.000000e+00 0 1.340787e-01 -3.251367e-02 -4.184088e-01 -8.642880e-01 3.472230e+00 0 0 TRUE FALSE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3800942 0.3996124 U 0.4686274 0.6162291 13773 129 184316 184317 1 -17 Convergent + - 0.000000 0 0.000000 0.00000000 1.602759 3.491458 1.1034950 - - - conserved within P. aerophilum 1.610737 3.537039 1.1267562 1618 Predicted nucleotide kinase F conserved hypothetical protein 0.000000e+00 0 6.364334e-05 2.411926e-02 3.090417e-01 7.694434e-01 1.908342e-04 0 8 FALSE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7731048 0.6545960 U 0.4686274 0.6162291 13773 129 184317 184318 1 43 Same - - 0.000000 0 0.000000 0.00000000 1.610737 3.537039 1.1267562 1618 Predicted nucleotide kinase F conserved hypothetical protein 1.715584 4.029313 1.1872641 142 Geranylgeranyl pyrophosphate synthase H polyprenyl synthetase 1.557260e-03 1 1.099290e-02 4.209718e-02 6.257200e-01 8.617224e-01 8.201158e-03 0 8 1 TRUE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.7965262 0.6439704 N 0.5492530 0.6245624 13773 129 184318 184319 1 42 Same - - 0.000000 0 0.000000 0.00000000 1.715584 4.029313 1.1872641 142 Geranylgeranyl pyrophosphate synthase H polyprenyl synthetase 1.680722 3.498307 1.0576154 - - - hypothetical protein 0.000000e+00 0 1.215348e-03 6.058662e-02 6.854412e-01 9.335326e-01 2.850733e-04 1 0 TRUE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8085259 0.6540676 U 0.4686274 0.6162291 13773 129 184319 184320 1 84 Divergent - + 0.000000 0 0.000000 0.00000000 1.680722 3.498307 1.0576154 - - - hypothetical protein 1.477025 3.121444 1.0592141 54 Riboflavin synthase beta-chain H riboflavin synthase 0.000000e+00 0 4.149259e-02 5.878093e-03 -4.242291e-02 3.219585e-01 3.864392e-01 0 5 TRUE FALSE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6007917 0.5147662 U 0.4686274 0.6162291 13773 129 184320 184321 1 -3 Convergent + - 0.000000 0 0.000000 -0.07864313 1.477025 3.121444 1.0592141 54 Riboflavin synthase beta-chain H riboflavin synthase 1.559680 3.345168 1.0986284 115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase EH branched-chain amino acid aminotransferase (ilvE) 1.921128e-02 5 6.831988e-03 2.775594e-03 8.130107e-02 2.608173e-01 1.933839e-01 5 55 FALSE FALSE 113 FALSE 0.4469764 0.2970905 0.5480306 0.4469764 0.7448207 0.6724471 0.5742403 0.5820196 U 0.4686274 0.5562327 13773 129 184321 184322 1 -3 Same - - 3.688879 0 7.067604 -1.26049231 1.559680 3.345168 1.0986284 115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase EH branched-chain amino acid aminotransferase (ilvE) 1.511154 3.205552 1.0917714 59 Ketol-acid reductoisomerase EH acetohydroxy acid isomeroreductase (ilvC) 1.062985e-01 54 2.354845e-03 6.471350e-03 7.569324e-02 4.412457e-01 4.293769e-02 55 54 TRUE FALSE 112 TRUE 2.8658703 0.2048851 0.5480306 2.8223619 0.7712119 1.0277769 0.6524431 0.6268270 U 0.4686274 0.4522736 13773 129 184322 184323 1 13 Same - - 0.000000 0 0.000000 0.00000000 1.511154 3.205552 1.0917714 59 Ketol-acid reductoisomerase EH acetohydroxy acid isomeroreductase (ilvC) 1.422973 3.117414 1.0815175 - - - acetolactate synthase small subunit 0.000000e+00 0 7.775830e-03 -1.698394e-03 -6.138758e-03 -1.104205e-01 5.819477e-01 54 0 TRUE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4880350 0.4794292 U 0.4686274 0.6162291 13773 129 184323 184324 1 -10 Same - - 0.000000 0 0.000000 0.00000000 1.422973 3.117414 1.0815175 - - - acetolactate synthase small subunit 1.546168 3.387238 1.1296398 28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome) EH acetolactate synthase large subunit (ilvB) 0.000000e+00 0 1.517691e-02 -2.693486e-03 1.000408e-02 -1.423099e-01 8.594983e-01 0 61 TRUE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4790360 0.4492667 U 0.4686274 0.6162291 13773 129 184324 184325 1 117 Same - - 0.000000 0 0.000000 -0.25131443 1.546168 3.387238 1.1296398 28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome) EH acetolactate synthase large subunit (ilvB) 1.564100 3.219845 1.0069466 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 2.630347e-03 1 3.215629e-04 1.068177e-02 1.550804e-01 5.782394e-01 3.138751e-03 61 1 TRUE FALSE 109 TRUE 0.4469764 0.2639739 0.5480306 0.4469764 0.6329203 0.5063263 0.7115627 0.6484515 U 0.4686274 0.5457943 13773 129 184325 184326 1 50 Divergent - + 0.000000 0 0.000000 0.00000000 1.564100 3.219845 1.0069466 494 NTP pyrophosphohydrolases including oxidative damage repair enzymes LR mutT/nudix family protein 1.576443 3.218609 0.9602702 - - - hypothetical protein 0.000000e+00 0 1.523561e-04 1.409402e-02 1.929816e-01 6.454483e-01 8.505079e-04 1 0 TRUE FALSE 108 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7352967 0.6520519 U 0.4686274 0.6162291 13773 129 184326 184327 1 -25 Convergent + - 0.000000 0 0.000000 0.00000000 1.576443 3.218609 0.9602702 - - - hypothetical protein 1.539256 3.294897 1.0288293 - - - hypothetical protein 0.000000e+00 0 1.382872e-03 1.098731e-02 1.290975e-01 5.807779e-01 1.170980e-02 0 0 FALSE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7131820 0.6420996 U 0.4686274 0.6162291 13773 129 184327 184328 1 553 Same - - 0.000000 0 0.000000 0.00000000 1.539256 3.294897 1.0288293 - - - hypothetical protein 1.489283 3.311689 1.1134404 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J mRNA 3'-end processing factor, conjectural 0.000000e+00 0 2.497330e-03 3.329127e-03 4.370375e-02 3.110921e-01 7.381042e-02 0 9 TRUE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5966647 0.6167268 U 0.4686274 0.6162291 13773 129 184328 184329 1 210 Divergent - + 0.000000 0 0.000000 -0.61090494 1.489283 3.311689 1.1134404 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J mRNA 3'-end processing factor, conjectural 1.582946 3.580740 1.1155095 198 Ribosomal protein L24 J ribosomal protein L24 1.528708e-01 9 8.772827e-03 4.984540e-03 1.193219e-01 3.655753e-01 1.568233e-01 J 9 11 TRUE FALSE 107 FALSE 0.4469764 0.2309594 0.5480306 0.4469764 0.7702221 1.0876510 0.6178516 0.5907175 Y 1.4497162 0.6392750 13773 129 184329 184330 1 5 Same + + 25.178204 0 32.982047 32.98204723 1.582946 3.580740 1.1155095 198 Ribosomal protein L24 J ribosomal protein L24 1.594934 3.536136 1.1169319 1471 Ribosomal protein S4E J ribosomal protein S4 3.056801e-01 11 1.437018e-04 1.888327e-02 2.499007e-01 7.170653e-01 6.414149e-04 J 11 11 FALSE FALSE 108 TRUE 2.2337636 1.9903398 0.5480306 2.3762174 0.7764261 1.2244861 0.7599046 0.6527891 Y 1.4497162 0.9303678 13773 129 184330 184331 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.594934 3.536136 1.1169319 1471 Ribosomal protein S4E J ribosomal protein S4 1.438135 3.049917 1.0235899 - - - hypothetical protein 0.000000e+00 0 2.458577e-02 -1.903016e-03 -5.339052e-02 -3.166434e-02 8.035203e-01 11 0 FALSE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5117420 0.4550988 U 0.4686274 0.6162291 13773 129 184331 184332 1 32 Same - - 0.000000 0 0.000000 0.00000000 1.438135 3.049917 1.0235899 - - - hypothetical protein 1.538263 3.389082 1.0953439 4608 ABC-type oligopeptide transport system, ATPase component E oligopeptide transport ATP-binding protein, putative 0.000000e+00 0 1.002558e-02 -1.151695e-03 2.598960e-02 -2.603826e-02 5.530428e-01 0 5 TRUE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5135303 0.4833863 U 0.4686274 0.6162291 13773 129 184332 184333 1 3 Same - - 6.962243 0 12.568862 12.56886219 1.538263 3.389082 1.0953439 4608 ABC-type oligopeptide transport system, ATPase component E oligopeptide transport ATP-binding protein, putative 1.469132 3.311856 1.1051835 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP oligopeptide transport ATP-binding protein, putative 9.486128e-02 5 4.779084e-03 1.541010e-03 2.039054e-02 1.855226e-01 1.974551e-01 5 6 TRUE FALSE 107 TRUE 2.7529488 1.8718624 0.5480306 2.6981093 0.7448207 0.9927460 0.5441739 0.5805111 U 0.4686274 0.8750578 13773 129 184333 184334 1 47 Divergent - + 0.000000 0 0.000000 -0.18221272 1.469132 3.311856 1.1051835 444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component EP oligopeptide transport ATP-binding protein, putative 1.586615 3.474283 1.1151371 524 Sugar kinases, ribokinase family G kinase, conjectural 3.505284e-02 1 1.380220e-02 2.398735e-03 9.442014e-02 2.207740e-01 3.348527e-01 6 1 TRUE FALSE 106 FALSE 0.4469764 0.2749489 0.5480306 0.4469764 0.6329203 0.7716100 0.5573097 0.5297247 U 0.4686274 0.5492585 13773 129 184334 184335 1 -34 Convergent + - 0.000000 0 0.000000 0.00000000 1.586615 3.474283 1.1151371 524 Sugar kinases, ribokinase family G kinase, conjectural 1.622632 3.702503 1.1929767 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein with 2 CBS domains 1.557260e-03 1 1.297232e-03 2.315530e-02 3.195066e-01 7.572159e-01 3.492148e-03 0 1 8 FALSE FALSE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.7689766 0.6477695 N 0.5492530 0.6245624 13773 129 184335 184336 1 150 Divergent - + 0.000000 0 0.000000 -0.13150953 1.622632 3.702503 1.1929767 2524 Predicted transcriptional regulator, contains C-terminal CBS domains K conserved protein with 2 CBS domains 1.504294 3.315029 1.0861687 111 Phosphoglycerate dehydrogenase and related dehydrogenases HE D-3-phosphoglycerate dehydrogenase (serA) 1.371145e-03 8 1.400397e-02 9.058672e-03 5.929540e-02 4.808597e-01 1.340133e-01 8 14 TRUE FALSE 106 FALSE 0.4469764 0.2892175 0.5480306 0.4469764 0.7652913 0.4797505 0.6669027 0.5973082 U 0.4686274 0.5537552 13773 129 184336 184337 1 -3 Same + + 5.159055 0 9.207937 9.02572477 1.504294 3.315029 1.0861687 111 Phosphoglycerate dehydrogenase and related dehydrogenases HE D-3-phosphoglycerate dehydrogenase (serA) 1.473669 3.304280 1.0988503 75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase E aminotransferase (class 5) 8.936729e-02 6 9.378824e-04 1.178409e-03 2.866933e-02 1.623363e-01 5.300950e-02 14 6 FALSE FALSE 107 TRUE 2.8135752 1.8292238 0.5480306 2.7787754 0.7537284 0.9783689 0.5351216 0.6228520 U 0.4686274 0.8681381 13773 129 184337 184338 1 -19 Same + + 0.000000 0 0.000000 -0.18221272 1.473669 3.304280 1.0988503 75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase E aminotransferase (class 5) 1.516912 3.435952 1.1088199 1578 Uncharacterized conserved protein S conserved hypothetical protein 5.190299e-03 5 1.869980e-03 1.459494e-03 4.744386e-02 1.833280e-01 8.958605e-02 6 5 FALSE FALSE 108 TRUE 0.4469764 0.2749489 0.5480306 0.4469764 0.7448207 0.5453500 0.5432716 0.6110830 U 0.4686274 0.5492585 13773 129 184338 184339 1 -19 Convergent + - 0.000000 0 0.000000 0.00000000 1.516912 3.435952 1.1088199 1578 Uncharacterized conserved protein S conserved hypothetical protein 1.451333 3.242708 1.0403730 - - - conserved hypothetical protein 9.520652e-04 1 4.300552e-03 -3.896531e-06 9.790648e-03 5.647985e-02 2.596853e-01 5 1 FALSE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.5186920 0.5580942 U 0.4686274 0.6162291 13773 129 184339 184340 1 63 Same - - 0.000000 0 0.000000 -0.13353139 1.451333 3.242708 1.0403730 - - - conserved hypothetical protein 1.553839 3.392256 1.1277923 1746 tRNA nucleotidyltransferase (CCA-adding enzyme) J tRNA nucleotidyltransferase 2.507089e-02 1 1.050734e-02 -6.092625e-06 4.731898e-02 7.085131e-02 4.396820e-01 1 12 TRUE FALSE 108 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.7074534 0.5180748 0.5054889 U 0.4686274 0.5517368 13773 129 184340 184341 1 -3 Same - - 16.075597 0 21.531393 21.15896465 1.553839 3.392256 1.1277923 1746 tRNA nucleotidyltransferase (CCA-adding enzyme) J tRNA nucleotidyltransferase 1.568878 3.483722 1.0639774 1514 2'-5' RNA ligase J conserved hypothetical protein 1.615812e-01 12 2.261660e-04 1.203582e-02 1.698633e-01 6.063014e-01 1.981377e-03 J 12 23 TRUE FALSE 107 TRUE 2.5192435 1.9277920 0.5480306 2.5620814 0.7776747 1.1016449 0.7222153 0.6503033 Y 1.4497162 0.9225326 13773 129 184341 184342 1 -3 Same - - 0.000000 0 0.000000 -0.13353139 1.568878 3.483722 1.0639774 1514 2'-5' RNA ligase J conserved hypothetical protein 1.528385 3.353882 1.0784475 1522 Transcriptional regulators K DNA binding transcriptional repressor, conjectural 1.599790e-02 1 1.639671e-03 9.045360e-03 1.065002e-01 5.362017e-01 1.742481e-02 0 23 1 TRUE FALSE 106 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.6457313 0.6896749 0.6390912 N 0.5492530 0.5604716 13773 129 184342 184343 1 33 Same - - 0.000000 0 0.000000 0.00000000 1.528385 3.353882 1.0784475 1522 Transcriptional regulators K DNA binding transcriptional repressor, conjectural 1.588990 3.455744 1.1215137 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB (TFIIB) 0.000000e+00 0 3.672947e-03 1.059382e-02 1.776302e-01 5.675314e-01 3.197592e-02 K 1 0 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7063502 0.6315628 Y 1.4497162 0.7118045 13773 129 184343 184344 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.588990 3.455744 1.1215137 1405 Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB K transcription initiation factor IIB (TFIIB) 1.457763 3.107900 1.0606085 3277 RNA-binding protein involved in rRNA processing J hypothetical protein 0.000000e+00 0 1.722031e-02 8.765601e-04 -1.699039e-02 1.295169e-01 4.834678e-01 0 0 0 TRUE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5239600 0.4957719 N 0.5492530 0.6245624 13773 129 184344 184345 1 158 Divergent - + 0.000000 0 0.000000 0.00000000 1.457763 3.107900 1.0606085 3277 RNA-binding protein involved in rRNA processing J hypothetical protein 1.466433 3.149277 1.0587275 2007 Ribosomal protein S8E J ribosomal protein S8 0.000000e+00 0 7.516879e-05 9.581555e-05 2.232941e-02 3.563181e-02 6.493663e-03 J 0 10 TRUE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176617 0.6450314 Y 1.4497162 0.7118045 13773 129 184345 184346 1 -3 Same + + 2.833213 0 2.833213 2.39433438 1.466433 3.149277 1.0587275 2007 Ribosomal protein S8E J ribosomal protein S8 1.639334 3.517301 1.0630786 1400 Signal recognition particle 19 kDa protein U signal recognition particle 1.313252e-01 8 2.989478e-02 2.826735e-03 1.429148e-01 2.146861e-01 4.717992e-01 0 10 8 FALSE FALSE 104 TRUE 2.9141387 1.6830070 0.5480306 2.9300754 0.7652913 1.0689402 0.5551901 0.4985726 N 0.5492530 0.8482854 13773 129 184346 184347 1 0 Same + + 0.000000 0 0.000000 -0.29999575 1.639334 3.517301 1.0630786 1400 Signal recognition particle 19 kDa protein U signal recognition particle 1.461329 3.234707 1.0514674 1100 GTPase SAR1 and related small G proteins R conserved hypothetical protein 2.159066e-02 5 3.168600e-02 1.867380e-03 -4.687829e-02 1.744325e-01 5.338080e-01 8 5 FALSE FALSE 105 TRUE 0.4469764 0.2548739 0.5480306 0.4469764 0.7448207 0.6890474 0.5401862 0.4864093 U 0.4686274 0.5429185 13773 129 184347 184348 1 -15 Convergent + - 0.000000 0 0.000000 -0.39347110 1.461329 3.234707 1.0514674 1100 GTPase SAR1 and related small G proteins R conserved hypothetical protein 1.524551 3.315540 1.0594453 2139 Ribosomal protein L21E J ribosomal protein L21 7.949421e-02 5 3.997084e-03 7.268996e-04 4.257795e-02 1.223500e-01 2.078184e-01 5 5 FALSE FALSE 106 FALSE 0.4469764 0.2430094 0.5480306 0.4469764 0.7448207 0.9537343 0.5225948 0.5771537 U 0.4686274 0.5391647 13773 129 184348 184349 1 88 Divergent - + 0.000000 0 0.000000 0.00000000 1.524551 3.315540 1.0594453 2139 Ribosomal protein L21E J ribosomal protein L21 1.442070 3.307552 1.1072131 1460 Uncharacterized protein conserved in archaea S conserved hypothetical protein 9.520652e-04 1 6.803143e-03 -6.820354e-04 -6.080003e-04 5.448787e-03 4.057582e-01 5 1 TRUE FALSE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4684288 0.5194420 0.5114888 U 0.4686274 0.6162291 13773 129 184349 184350 1 -3 Same + + 4.025352 0 4.025352 4.02535169 1.442070 3.307552 1.1072131 1460 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.517416 3.158394 0.9969108 1491 Predicted RNA-binding protein J conserved hypothetical protein 2.630109e-02 1 5.676949e-03 -6.155119e-04 2.438999e-02 5.111882e-03 3.565089e-01 1 11 FALSE FALSE 106 TRUE 2.8601813 1.7461844 0.5480306 2.9073706 0.6329203 0.7172240 0.5194777 0.5232211 U 0.4686274 0.8548323 13773 129 184350 184351 1 2 Convergent + - 0.000000 0 0.000000 -0.90538035 1.517416 3.158394 0.9969108 1491 Predicted RNA-binding protein J conserved hypothetical protein 1.619530 3.394650 1.0504393 231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) J translation initiation factor aIF-5A 3.056801e-01 11 1.042733e-02 1.110089e-02 2.112548e-01 5.413948e-01 8.326967e-02 J 11 11 FALSE FALSE 107 FALSE 0.4469764 0.2144997 0.5480306 0.4469764 0.7764261 1.2244861 0.6934733 0.6130924 Y 1.4497162 0.6344249 13773 129 184351 184352 1 31 Same - - 0.000000 0 0.000000 -1.03891174 1.619530 3.394650 1.0504393 231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) J translation initiation factor aIF-5A 1.448335 3.065560 1.0671564 5 Purine nucleoside phosphorylase F purine nucleoside phosphorylase 1.068399e-01 11 2.930775e-02 -5.141506e-04 -5.704233e-02 5.901135e-02 6.857314e-01 0 11 39 TRUE FALSE 106 TRUE 0.4469764 0.2100064 0.5480306 0.4469764 0.7764261 1.0315374 0.5186128 0.4659563 N 0.5492530 0.5375086 13773 129 184352 184353 1 32 Divergent - + 0.000000 0 0.000000 0.00000000 1.448335 3.065560 1.0671564 5 Purine nucleoside phosphorylase F purine nucleoside phosphorylase 1.462763 3.062716 1.0402784 - - - hypothetical protein 0.000000e+00 0 2.081753e-04 -3.476969e-05 2.063573e-02 1.362580e-02 1.972483e-02 39 0 TRUE FALSE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183388 0.6377141 U 0.4686274 0.6162291 13773 129 184353 184354 1 26 Same + + 0.000000 0 0.000000 0.00000000 1.462763 3.062716 1.0402784 - - - hypothetical protein 1.391250 2.887626 1.0228993 23 Translation initiation factor 1 (eIF-1/SUI1) and related proteins J translation initiation factor SUI1 homolog 0.000000e+00 0 5.114072e-03 -6.838404e-04 2.159939e-02 -1.017182e-01 4.888188e-01 0 9 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4904610 0.4944036 U 0.4686274 0.6162291 13773 129 184354 184355 1 258 Convergent + - 0.000000 0 0.000000 0.00000000 1.391250 2.887626 1.0228993 23 Translation initiation factor 1 (eIF-1/SUI1) and related proteins J translation initiation factor SUI1 homolog 1.462619 3.280351 1.0717500 - - - hypothetical protein 0.000000e+00 0 5.093502e-03 -6.751817e-04 3.977661e-03 -1.009619e-01 4.866749e-01 9 0 FALSE FALSE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4908051 0.4946318 U 0.4686274 0.6162291 13773 129 184355 184356 1 54 Same - - 0.000000 0 0.000000 0.00000000 1.462619 3.280351 1.0717500 - - - hypothetical protein 1.488151 3.195195 1.0998384 18 Arginyl-tRNA synthetase J arginyl-tRNA synthetase 0.000000e+00 0 6.518603e-04 4.126589e-04 2.867380e-02 8.822370e-02 5.091032e-02 0 59 TRUE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177310 0.6235705 U 0.4686274 0.6162291 13773 129 184356 184357 1 67 Divergent - + 0.000000 0 0.000000 -0.29619069 1.488151 3.195195 1.0998384 18 Arginyl-tRNA synthetase J arginyl-tRNA synthetase 1.643818 3.516953 1.1364555 2053 Ribosomal protein S28E/S33 J ribosomal protein S28 9.399069e-03 3 2.423242e-02 7.073170e-03 1.940399e-01 3.988240e-01 2.457968e-01 J 59 3 TRUE FALSE 105 FALSE 0.4469764 0.2560029 0.5480306 0.4469764 0.7136133 0.5898397 0.6342015 0.5639198 Y 1.4497162 0.6466000 13773 129 184357 184358 1 -3 Same + + 5.030438 0 5.030438 5.03043792 1.643818 3.516953 1.1364555 2053 Ribosomal protein S28E/S33 J ribosomal protein S28 1.241528 2.637329 1.0132138 2075 Ribosomal protein L24E J ribosomal protein L24 3.242777e-02 3 1.618375e-01 -4.038333e-02 -4.336195e-01 -9.185038e-01 3.678271e+00 J 3 10 FALSE FALSE 106 TRUE 2.8195094 1.7656869 0.5480306 2.8851565 0.7136133 0.7515835 0.3784150 0.3991330 Y 1.4497162 0.9032175 13773 129 184358 184359 1 1 Convergent + - 7.992945 0 15.796788 15.47112230 1.241528 2.637329 1.0132138 2075 Ribosomal protein L24E J ribosomal protein L24 1.551842 3.327242 1.0724503 1358 Ribosomal protein HS6-type (S12/L30/L7a) J ribosomal protein L7 2.329131e-01 9 9.629481e-02 -2.108078e-02 -3.119689e-01 -7.411953e-01 3.024343e+00 J 10 9 FALSE FALSE 107 FALSE 2.7093791 1.8841831 0.5480306 2.6611079 0.7702221 1.1625725 0.3851048 0.4009795 Y 1.4497162 0.9166846 13773 129 184359 184360 1 32 Same - - 0.000000 0 0.000000 -0.15154990 1.551842 3.327242 1.0724503 1358 Ribosomal protein HS6-type (S12/L30/L7a) J ribosomal protein L7 1.544364 3.619103 1.1930055 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 3.541483e-02 3 5.591739e-05 9.338943e-03 1.262582e-01 5.438492e-01 3.981602e-04 0 9 3 TRUE FALSE 106 TRUE 0.4469764 0.2768227 0.5480306 0.4469764 0.7136133 0.7756969 0.6946224 0.6536323 N 0.5492530 0.5585917 13773 129 184360 184361 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.544364 3.619103 1.1930055 4177 ABC-type branched-chain amino acid transport system, permease component E branched-chain amino acid transport permease protein 1.526301 3.685455 1.1828287 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 5.631536e-04 1 3.262819e-04 6.964349e-03 9.446585e-02 4.768452e-01 5.204355e-03 E 3 1 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4562299 0.6655223 0.6462385 Y 1.4497162 0.7118045 13773 129 184361 184362 1 111 Divergent - + 0.000000 0 0.000000 -0.05715841 1.526301 3.685455 1.1828287 559 Branched-chain amino acid ABC-type transport system, permease components E branched-chain amino acid transport permease protein 1.494560 3.278284 1.0999772 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 1.725611e-02 1 1.007519e-03 3.233561e-03 4.902762e-02 3.078367e-01 3.449387e-02 E 1 21 TRUE FALSE 104 FALSE 0.4469764 0.3074832 0.5480306 0.4469764 0.6329203 0.6548124 0.5948838 0.6302077 Y 1.4497162 0.6614403 13773 129 184362 184363 1 33 Same + + 4.025352 0 4.025352 3.47724351 1.494560 3.278284 1.0999772 683 ABC-type branched-chain amino acid transport systems, periplasmic component E branched-chain amino acid binding protein 1.498062 3.172201 1.0414169 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 5.768028e-02 8 1.226756e-05 2.014574e-03 4.509171e-02 2.335810e-01 7.633367e-04 E 21 8 FALSE FALSE 105 TRUE 2.8601813 1.7423040 0.5480306 2.9073706 0.7652913 0.8758269 0.5626884 0.6522016 Y 1.4497162 0.9001294 13773 129 184363 184364 1 403 Same + + 0.000000 0 0.000000 0.00000000 1.498062 3.172201 1.0414169 411 ABC-type branched-chain amino acid transport systems, ATPase component E branched-chain amino acid transport ATP-binding protein 1.525150 3.554011 1.1851881 1361 S-layer domain M conserved hypothetical protein 1.557260e-03 1 7.337422e-04 3.442199e-03 6.926892e-02 3.225098e-01 2.285828e-02 0 8 1 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4867810 0.6010523 0.6363673 N 0.5492530 0.6245624 13773 129 184364 184365 1 -7 Same + + 0.000000 0 0.000000 -0.07232066 1.525150 3.554011 1.1851881 1361 S-layer domain M conserved hypothetical protein 1.454220 3.447871 1.1976571 477 Permeases of the major facilitator superfamily GEPR antibiotic resistance (efflux) protein, conjectural 1.188643e-02 1 5.031126e-03 2.084858e-04 9.380453e-03 7.963204e-02 2.763709e-01 1 31 FALSE FALSE 107 TRUE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.6108778 0.5177707 0.5518172 U 0.4686274 0.5573725 13773 129 184365 184366 1 10 Same + + 0.000000 0 0.000000 0.00000000 1.454220 3.447871 1.1976571 477 Permeases of the major facilitator superfamily GEPR antibiotic resistance (efflux) protein, conjectural 1.405457 3.418685 1.1833821 477 Permeases of the major facilitator superfamily GEPR conserved hypothetical protein 1.494197e-02 2 2.377789e-03 -1.298450e-04 2.455786e-02 -4.400966e-02 2.315508e-01 31 2 FALSE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.6389201 0.5078076 0.5704308 U 0.4686274 0.6162291 13773 129 184366 184367 1 -18 Same + + 0.000000 0 0.000000 0.00000000 1.405457 3.418685 1.1833821 477 Permeases of the major facilitator superfamily GEPR conserved hypothetical protein 1.606888 3.415759 1.0124716 500 SAM-dependent methyltransferases QR hypothetical protein 0.000000e+00 0 4.057462e-02 -7.142830e-03 -6.734499e-03 -3.143940e-01 1.526732e+00 2 0 FALSE FALSE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4364695 0.4163522 U 0.4686274 0.6162291 13773 129 184367 184368 1 75 Same + + 0.000000 0 0.000000 0.00000000 1.606888 3.415759 1.0124716 500 SAM-dependent methyltransferases QR hypothetical protein 1.371638 2.923444 1.0054182 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 0.000000e+00 0 5.534270e-02 -1.240151e-02 -1.695133e-01 -5.695446e-01 2.330133e+00 0 0 FALSE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3968347 0.4049063 U 0.4686274 0.6162291 13773 129 184368 184369 1 31 Same + + 0.000000 0 0.000000 0.00000000 1.371638 2.923444 1.0054182 467 RecA-superfamily ATPases implicated in signal transduction T conserved hypothetical protein 1.456060 3.228297 1.1186733 541 Signal recognition particle GTPase U signal recognition particle (srp54 family), putative 0.000000e+00 0 7.127079e-03 -3.722359e-04 2.873537e-04 -9.118694e-02 6.236514e-01 0 0 69 FALSE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4950458 0.4741862 N 0.5492530 0.6245624 13773 129 184369 184370 1 84 Same + + 0.000000 0 0.000000 0.00000000 1.456060 3.228297 1.1186733 541 Signal recognition particle GTPase U signal recognition particle (srp54 family), putative 1.454102 3.203120 1.0850626 - - - hypothetical protein 0.000000e+00 0 3.836091e-06 1.264201e-05 2.084882e-02 1.703018e-02 3.681215e-04 69 0 FALSE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5179424 0.6536833 U 0.4686274 0.6162291 13773 129 184370 184371 1 20 Same + + 0.000000 0 0.000000 0.00000000 1.454102 3.203120 1.0850626 - - - hypothetical protein 1.531064 3.378650 1.1294534 1258 Predicted pseudouridylate synthase J conserved hypothetical protein 0.000000e+00 0 5.923193e-03 2.158016e-04 3.936170e-02 8.301052e-02 3.173243e-01 0 10 FALSE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177057 0.5362123 U 0.4686274 0.6162291 13773 129 184371 184372 1 29 Same + + 0.000000 0 0.000000 -0.13353139 1.531064 3.378650 1.1294534 1258 Predicted pseudouridylate synthase J conserved hypothetical protein 1.441442 3.037261 1.0540496 519 GMP synthase, PP-ATPase domain/subunit F GMP synthetase (glutamine-hydrolysing) 1.596409e-01 10 8.032100e-03 -7.928086e-04 -4.400011e-03 1.576149e-03 4.654946e-01 0 10 56 FALSE FALSE 114 TRUE 0.4469764 0.2828094 0.5480306 0.4469764 0.7739415 1.0976286 0.5198398 0.5002274 N 0.5492530 0.5604716 13773 129 184372 184373 1 191 Same + + 0.000000 0 0.000000 -5.46168569 1.441442 3.037261 1.0540496 519 GMP synthase, PP-ATPase domain/subunit F GMP synthetase (glutamine-hydrolysing) 1.447659 3.196209 1.1223655 405 Gamma-glutamyltransferase E gamma-glutamyltransferase 2.977471e-02 27 3.865303e-05 3.715600e-05 2.095606e-02 1.360577e-04 3.225333e-03 0 56 27 FALSE FALSE 115 TRUE 0.4469764 0.1812706 0.5480306 0.4469764 0.7761702 0.7334991 0.5199484 0.6482245 N 0.5492530 0.5283954 13773 129 184373 184374 1 596 Convergent + - 0.000000 0 0.000000 0.00000000 1.447659 3.196209 1.1223655 405 Gamma-glutamyltransferase E gamma-glutamyltransferase 1.275677 2.793245 1.0092737 - - - paREP2b 0.000000e+00 0 2.957779e-02 6.561021e-04 1.067836e-01 -5.759776e-02 1.068677e+00 27 0 FALSE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5046912 0.4347792 U 0.4686274 0.6162291 13773 129 184374 184375 1 124 Divergent - + 0.000000 0 0.000000 0.00000000 1.275677 2.793245 1.0092737 - - - paREP2b 1.488355 3.233072 1.0371237 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 0.000000e+00 0 4.523209e-02 -6.494906e-03 -1.301430e-01 -4.203889e-01 1.976797e+00 0 0 TRUE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4152376 0.4082992 U 0.4686274 0.6162291 13773 129 184375 184376 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.488355 3.233072 1.0371237 1977 Molybdopterin converting factor, small subunit H conserved hypothetical protein 1.391594 2.979492 1.0223043 491 Zn-dependent hydrolases, including glyoxylases R beta-lactamase-like protein 0.000000e+00 0 9.362770e-03 -2.210318e-03 5.055080e-04 -2.108565e-01 8.467389e-01 0 18 FALSE FALSE 116 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4614726 0.4508449 U 0.4686274 0.6162291 13773 129 184376 184377 1 264 Divergent - + 0.000000 0 0.000000 -1.11479277 1.391594 2.979492 1.0223043 491 Zn-dependent hydrolases, including glyoxylases R beta-lactamase-like protein 1.496427 3.334129 1.0919861 1489 DNA-binding protein, stimulates sugar fermentation R sugar fermentation stimulation protein, conjectural 2.843585e-02 18 1.098995e-02 -2.692987e-03 -1.468021e-02 -2.356190e-01 9.425236e-01 18 26 TRUE FALSE 115 FALSE 0.4469764 0.2064359 0.5480306 0.4469764 0.7781393 0.7246741 0.4548918 0.4432769 U 0.4686274 0.5275674 13773 129 184377 184378 1 -20 Convergent + - 0.000000 0 0.000000 -0.35205230 1.496427 3.334129 1.0919861 1489 DNA-binding protein, stimulates sugar fermentation R sugar fermentation stimulation protein, conjectural 1.461660 3.092800 1.0375546 3342 Uncharacterized conserved protein S conserved hypothetical protein 3.077255e-02 5 1.208744e-03 4.623699e-04 2.126125e-02 9.580112e-02 8.019807e-02 26 5 FALSE FALSE 116 FALSE 0.4469764 0.2474825 0.5480306 0.4469764 0.7448207 0.7360470 0.5180775 0.6143382 U 0.4686274 0.5405805 13773 129 184378 184379 1 39 Divergent - + 0.000000 0 0.000000 0.00000000 1.461660 3.092800 1.0375546 3342 Uncharacterized conserved protein S conserved hypothetical protein 1.456187 3.151223 1.0334352 491 Zn-dependent hydrolases, including glyoxylases R beta-lactamase-like protein 3.891536e-03 4 2.995376e-05 4.922160e-05 2.110387e-02 2.822167e-02 3.225333e-03 5 4 TRUE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.5343748 0.5173827 0.6482245 U 0.4686274 0.6162291 13773 129 184379 184380 1 343 Same + + 0.000000 0 0.000000 -0.23211222 1.456187 3.151223 1.0334352 491 Zn-dependent hydrolases, including glyoxylases R beta-lactamase-like protein 1.411738 2.998015 1.0700575 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G pyruvate, phosphate dikinase 3.186152e-03 4 1.975683e-03 -1.901081e-04 2.244986e-02 -4.238698e-02 1.940595e-01 4 25 FALSE FALSE 116 TRUE 0.4469764 0.2694386 0.5480306 0.4469764 0.7323301 0.5200508 0.5083517 0.5817361 U 0.4686274 0.5475198 13773 129 184380 184381 1 192 Same + + 0.000000 0 0.000000 0.00000000 1.411738 2.998015 1.0700575 574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase G pyruvate, phosphate dikinase 1.439164 3.019646 0.9816170 - - - hypothetical protein 0.000000e+00 0 7.521911e-04 4.849135e-04 2.279384e-02 5.498852e-03 7.846878e-02 25 0 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5194238 0.6152238 U 0.4686274 0.6162291 13773 129 184381 184382 1 388 Convergent + - 0.000000 0 0.000000 0.00000000 1.439164 3.019646 0.9816170 - - - hypothetical protein 1.526446 3.463963 1.0399952 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein part 2, authentic frameshift 0.000000e+00 0 7.617999e-03 -9.177779e-04 2.393185e-02 -1.211444e-02 4.571545e-01 0 0 FALSE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178647 0.5026900 U 0.4686274 0.6162291 13773 129 184382 184383 1 57 Same - - 0.000000 0 0.000000 0.00000000 1.526446 3.463963 1.0399952 640 Predicted transcriptional regulators K P. aerophilum family 453, possible regulatory protein part 2, authentic frameshift 1.438163 3.599247 1.2080602 - - - P. aerophilum family 453, possible regulatory protein part 1, authentic frameshift 0.000000e+00 0 7.793751e-03 -9.929113e-04 -4.732063e-03 -2.271457e-02 4.792082e-01 0 0 TRUE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5144700 0.4968338 U 0.4686274 0.6162291 13773 129 184383 184384 1 39 Same - - 0.000000 0 0.000000 0.00000000 1.438163 3.599247 1.2080602 - - - P. aerophilum family 453, possible regulatory protein part 1, authentic frameshift 1.335404 2.951318 0.9909608 - - - hypothetical protein 0.000000e+00 0 1.055951e-02 1.534479e-03 7.239992e-02 2.949978e-02 6.718212e-01 0 0 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173840 0.4681425 U 0.4686274 0.6162291 13773 129 184384 184385 1 54 Same - - 0.000000 0 0.000000 0.00000000 1.335404 2.951318 0.9909608 - - - hypothetical protein 1.501950 3.295474 1.0495263 1192 ATPases involved in chromosome partitioning D hypothetical protein 0.000000e+00 0 2.773754e-02 -5.864048e-03 -7.550054e-02 -4.418412e-01 1.880876e+00 0 0 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4130607 0.4098972 U 0.4686274 0.6162291 13773 129 184385 184386 1 68 Same - - 0.000000 0 0.000000 0.00000000 1.501950 3.295474 1.0495263 1192 ATPases involved in chromosome partitioning D hypothetical protein 1.672408 3.496300 1.0448260 - - - hypothetical protein 0.000000e+00 0 2.905610e-02 1.117386e-02 2.689442e-01 4.930519e-01 1.900237e-01 0 0 TRUE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6696858 0.5828520 U 0.4686274 0.6162291 13773 129 184386 184387 1 40 Same - - 0.000000 0 0.000000 0.00000000 1.672408 3.496300 1.0448260 - - - hypothetical protein 1.524105 3.401145 1.0682468 - - - hypothetical protein 0.000000e+00 0 2.199373e-02 1.607061e-02 9.801694e-02 6.108284e-01 9.756633e-02 0 0 TRUE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7234635 0.6075710 U 0.4686274 0.6162291 13773 129 184387 184388 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.524105 3.401145 1.0682468 - - - hypothetical protein 1.491872 3.328195 1.1227210 - - - conserved within P. aerophilum 0.000000e+00 0 1.038971e-03 2.943372e-03 4.588694e-02 2.911517e-01 3.477953e-02 0 0 TRUE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5898755 0.6300598 U 0.4686274 0.6162291 13773 129 184388 184389 1 111 Divergent - + 0.000000 0 0.000000 0.00000000 1.491872 3.328195 1.1227210 - - - conserved within P. aerophilum 1.529168 3.424869 1.1527120 - - - conserved within P. aerophilum 0.000000e+00 0 1.390973e-03 3.148307e-03 6.874883e-02 3.061452e-01 4.817739e-02 0 0 TRUE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5941250 0.6245582 U 0.4686274 0.6162291 13773 129 184389 184390 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.529168 3.424869 1.1527120 - - - conserved within P. aerophilum 1.525580 3.377338 1.0970319 4917 Ethanolamine utilization protein E conserved within P. aerophilum 0.000000e+00 0 1.287505e-05 5.769922e-03 8.681652e-02 4.390494e-01 4.953443e-04 0 0 FALSE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6521166 0.6533218 U 0.4686274 0.6162291 13773 129 184390 184391 1 11 Convergent + - 0.000000 0 0.000000 0.00000000 1.525580 3.377338 1.0970319 4917 Ethanolamine utilization protein E conserved within P. aerophilum 1.379675 3.069407 1.0779179 1607 Acyl-CoA hydrolase I acyl coenzyme A thioester hydrolase 0.000000e+00 0 2.128818e-02 -5.320521e-03 -4.238634e-02 -3.820430e-01 1.532427e+00 0 0 3 FALSE FALSE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4225799 0.4162654 N 0.5492530 0.6245624 13773 129 184391 184392 1 47 Divergent - + 0.000000 0 0.000000 -0.26504093 1.379675 3.069407 1.0779179 1607 Acyl-CoA hydrolase I acyl coenzyme A thioester hydrolase 1.399214 3.096582 1.0653461 1701 Uncharacterized protein conserved in archaea S conserved hypothetical protein 8.710900e-02 3 3.817686e-04 3.742132e-03 5.834411e-02 2.515454e-01 2.475249e-02 3 10 TRUE FALSE 112 FALSE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.9694943 0.5699243 0.6354990 U 0.4686274 0.5447277 13773 129 184392 184393 1 113 Convergent + - 2.662588 0 2.662588 2.53753352 1.399214 3.096582 1.0653461 1701 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.494272 3.341402 1.1031191 1829 Predicted archaeal kinase (sugar kinase superfamily) R conserved hypothetical protein 5.662889e-02 2 9.035980e-03 -2.237374e-03 -7.667250e-03 -2.001827e-01 8.021450e-01 10 2 FALSE FALSE 113 FALSE 2.9244472 1.6943596 0.5480306 2.9399224 0.6838149 0.8734599 0.4648156 0.4553535 U 0.4686274 0.8454063 13773 129 184393 184394 1 -7 Same - - 0.000000 0 0.000000 -0.12505431 1.494272 3.341402 1.1031191 1829 Predicted archaeal kinase (sugar kinase superfamily) R conserved hypothetical protein 1.510165 3.314183 1.1025123 1893 Ketopantoate reductase H 2-dehydropantoate 2-reductase (ketopantoate reductase) 3.305270e-03 2 2.526027e-04 2.520112e-03 5.430637e-02 2.639260e-01 9.801456e-03 2 20 TRUE FALSE 112 TRUE 0.4469764 0.2924948 0.5480306 0.4469764 0.6838149 0.5221400 0.5753546 0.6429216 U 0.4686274 0.5547868 13773 129 184394 184395 1 33 Divergent - + 3.976562 0 3.976562 -0.39336177 1.510165 3.314183 1.1025123 1893 Ketopantoate reductase H 2-dehydropantoate 2-reductase (ketopantoate reductase) 1.478012 3.196044 1.1009704 413 Ketopantoate hydroxymethyltransferase H 3-methyl-2-oxobutanoate hydroxymethyltransferase 4.062402e-02 20 1.033864e-03 1.564454e-03 3.205712e-02 1.975104e-01 4.683919e-02 H 20 47 TRUE FALSE 111 FALSE 2.8636234 0.2434220 0.5480306 2.9099010 0.7777535 0.8050758 0.5493252 0.6252488 Y 1.4497162 0.5716244 13773 129 184395 184396 1 199 Convergent + - 0.000000 0 0.000000 0.00000000 1.478012 3.196044 1.1009704 413 Ketopantoate hydroxymethyltransferase H 3-methyl-2-oxobutanoate hydroxymethyltransferase 1.444387 3.451149 1.1866703 1079 Uncharacterized ABC-type transport system, permease component R sugar transport permease protein 0.000000e+00 0 1.130616e-03 -1.864872e-04 1.688248e-02 1.045171e-02 1.019290e-01 47 0 FALSE FALSE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5188563 0.6058668 U 0.4686274 0.6162291 13773 129 184396 184397 1 -9 Same - - 0.000000 0 0.000000 0.00000000 1.444387 3.451149 1.1866703 1079 Uncharacterized ABC-type transport system, permease component R sugar transport permease protein 1.467387 3.557422 1.2104852 4603 ABC-type uncharacterized transport system, permease component R ribose ABC transporter, permease protein 0.000000e+00 0 5.289897e-04 -1.120510e-04 1.995254e-02 7.281738e-03 4.551984e-02 0 2 TRUE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5191923 0.6257919 U 0.4686274 0.6162291 13773 129 184397 184398 1 -3 Same - - 0.000000 0 0.000000 -0.07410797 1.467387 3.557422 1.2104852 4603 ABC-type uncharacterized transport system, permease component R ribose ABC transporter, permease protein 1.427099 3.125951 1.0848809 3845 ABC-type uncharacterized transport systems, ATPase components R ribose ABC transport system ATP-binding protein 1.980709e-02 2 1.623140e-03 -3.885610e-04 1.704375e-02 -3.678211e-02 1.556100e-01 2 5 TRUE FALSE 110 TRUE 0.4469764 0.2976889 0.5480306 0.4469764 0.6838149 0.6786740 0.5098922 0.5912363 U 0.4686274 0.5564209 13773 129 184398 184399 1 2 Same - - 0.000000 0 0.000000 -0.13864649 1.427099 3.125951 1.0848809 3845 ABC-type uncharacterized transport systems, ATPase components R ribose ABC transport system ATP-binding protein 1.414562 2.987466 1.0591599 1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein R conserved hypothetical protein 1.455905e-02 5 1.571676e-04 8.947810e-04 3.314576e-02 3.979894e-02 1.255500e-02 5 11 TRUE FALSE 109 TRUE 0.4469764 0.2783565 0.5480306 0.4469764 0.7448207 0.6358151 0.5181880 0.6417146 U 0.4686274 0.5503332 13773 129 184399 184400 1 152 Same - - 0.000000 0 0.000000 -0.11778304 1.414562 2.987466 1.0591599 1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein R conserved hypothetical protein 1.474112 3.215897 1.1040878 1892 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.596264e-03 10 3.546192e-03 -8.367612e-04 8.819929e-03 -8.040598e-02 3.234056e-01 11 10 TRUE FALSE 108 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.7739415 0.4888096 0.4977688 0.5336048 U 0.4686274 0.5554237 13773 129 184400 184401 1 39 Same - - 0.000000 0 0.000000 -0.57197031 1.474112 3.215897 1.1040878 1892 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.485991 3.217962 1.0963276 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J conserved hypothetical protein 6.196037e-02 10 1.411150e-04 7.860350e-04 3.165733e-02 1.272899e-01 1.238361e-02 10 15 TRUE FALSE 107 TRUE 0.4469764 0.2318524 0.5480306 0.4469764 0.7739415 0.8917934 0.5236263 0.6418162 U 0.4686274 0.5356308 13773 129 184401 184402 1 64 Same - - 0.000000 0 0.000000 0.00000000 1.485991 3.217962 1.0963276 1236 Predicted exonuclease of the beta-lactamase fold involved in RNA processing J conserved hypothetical protein 1.575632 3.736657 1.1636582 - - - paREP2b 0.000000e+00 0 8.035419e-03 4.298430e-03 1.071542e-01 3.399729e-01 1.592641e-01 15 0 TRUE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6084792 0.5901897 U 0.4686274 0.6162291 13773 129 184402 184403 1 282 Same - - 0.000000 0 0.000000 0.00000000 1.575632 3.736657 1.1636582 - - - paREP2b 1.496313 3.262830 1.1330624 301 Thiamine biosynthesis ATP pyrophosphatase H thiamine biosynthesis protein (thiI), probable 0.000000e+00 0 6.291372e-03 5.580862e-03 5.191710e-02 3.925654e-01 1.119655e-01 0 6 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6311944 0.6025456 U 0.4686274 0.6162291 13773 129 184403 184404 1 18 Same - - 0.000000 0 0.000000 0.00000000 1.496313 3.262830 1.1330624 301 Thiamine biosynthesis ATP pyrophosphatase H thiamine biosynthesis protein (thiI), probable 1.390492 2.925277 1.0337227 58 Glucan phosphorylase G conserved hypothetical protein 8.421529e-03 6 1.119807e-02 -2.735678e-03 -6.954282e-03 -2.404140e-01 9.619951e-01 0 6 7 TRUE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7537284 0.5835606 0.4536163 0.4420467 N 0.5492530 0.6245624 13773 129 184404 184405 1 424 Divergent - + 0.000000 0 0.000000 0.00000000 1.390492 2.925277 1.0337227 58 Glucan phosphorylase G conserved hypothetical protein 1.471368 3.411565 1.1346539 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, degenerate 0.000000e+00 0 6.540911e-03 -1.216514e-03 -1.891515e-03 -1.391870e-01 6.056017e-01 7 0 TRUE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4796560 0.4761308 U 0.4686274 0.6162291 13773 129 184405 184406 1 603 Convergent + - 0.000000 0 0.000000 0.00000000 1.471368 3.411565 1.1346539 1672 Predicted ATPase (AAA+ superfamily) R conserved hypothetical protein, degenerate 1.465330 3.143941 1.1005618 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 0.000000e+00 0 3.646021e-05 2.784021e-04 2.347282e-02 6.221725e-02 3.053347e-03 0 2 FALSE FALSE 104 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183969 0.6486369 U 0.4686274 0.6162291 13773 129 184406 184407 1 93 Divergent - + 0.000000 0 0.000000 0.00000000 1.465330 3.143941 1.1005618 2414 Aldehyde:ferredoxin oxidoreductase C aldehyde ferredoxin oxidoreductase (aor) 1.477419 3.199303 1.1062053 1449 Alpha-amylase/alpha-mannosidase G conserved hypothetical protein 2.724640e-03 2 1.461315e-04 3.627259e-04 2.620560e-02 7.627183e-02 1.396859e-02 0 2 7 TRUE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5092572 0.5178484 0.6410384 N 0.5492530 0.6245624 13773 129 184407 184408 1 2 Same + + 2.856470 0 5.519058 5.51905803 1.477419 3.199303 1.1062053 1449 Alpha-amylase/alpha-mannosidase G conserved hypothetical protein 1.482965 3.149852 1.1103479 297 Glycogen synthase G glycogen synthase (starch (bacterial glycogen) synthase), putative 1.017063e-03 7 3.076612e-05 8.216946e-04 3.115650e-02 1.326239e-01 2.191648e-03 G 7 26 FALSE FALSE 104 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.7596462 0.4702064 0.5251564 0.6499017 Y 1.4497162 0.9052318 13773 129 184408 184409 1 30 Same + + 13.552950 0 25.845246 24.32755182 1.482965 3.149852 1.1103479 297 Glycogen synthase G glycogen synthase (starch (bacterial glycogen) synthase), putative 1.481110 3.119291 1.0538423 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ glucose-1-phosphate adenylyltransferase 9.663835e-02 20 3.441306e-06 9.382488e-04 3.141922e-02 1.457372e-01 1.702194e-04 26 20 FALSE FALSE 105 TRUE 2.6017854 1.9403913 0.5480306 2.5215647 0.7777535 1.0000170 0.5292096 0.6547351 U 0.4686274 0.8861994 13773 129 184409 184410 1 -23 Convergent + - 0.000000 0 0.000000 -0.24140159 1.481110 3.119291 1.0538423 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ glucose-1-phosphate adenylyltransferase 1.454768 3.113863 1.0831214 2106 Uncharacterized conserved protein S conserved hypothetical protein 6.252084e-05 7 6.939304e-04 1.002899e-04 1.969654e-02 4.809905e-02 6.106930e-02 20 7 FALSE FALSE 106 FALSE 0.4469764 0.2682666 0.5480306 0.4469764 0.7596462 0.4396706 0.5187418 0.6200599 U 0.4686274 0.5471498 13773 129 184410 184411 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.454768 3.113863 1.0831214 2106 Uncharacterized conserved protein S conserved hypothetical protein 1.437254 2.774469 1.0193066 - - - hypothetical protein 0.000000e+00 0 3.067402e-04 -4.771688e-05 2.065854e-02 -5.508276e-03 2.929010e-02 7 0 TRUE FALSE 105 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5196099 0.6334684 U 0.4686274 0.6162291 13773 129 184411 184412 1 86 Same - - 0.000000 0 0.000000 0.00000000 1.437254 2.774469 1.0193066 - - - hypothetical protein 1.559662 3.626043 1.2273226 - - - paREP2b 0.000000e+00 0 1.498378e-02 -1.530839e-03 3.209960e-02 -3.331352e-02 6.693073e-01 0 0 TRUE FALSE 104 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5112804 0.4688853 U 0.4686274 0.6162291 13773 129 184412 184413 1 71 Same - - 0.000000 0 0.000000 0.00000000 1.559662 3.626043 1.2273226 - - - paREP2b 1.503657 3.622126 1.1692871 201 Preprotein translocase subunit SecY U preprotein translocase secY subunit 0.000000e+00 0 3.136543e-03 5.658594e-03 6.406775e-02 4.104702e-01 6.031303e-02 0 12 TRUE FALSE 103 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6387864 0.6204913 U 0.4686274 0.6162291 13773 129 184413 184414 1 -3 Same - - 17.314937 0 27.781368 27.64783694 1.503657 3.622126 1.1692871 201 Preprotein translocase subunit SecY U preprotein translocase secY subunit 1.652173 3.471939 1.0424998 200 Ribosomal protein L15 J ribosomal protein L15 2.789541e-01 9 2.205699e-02 1.049361e-02 2.388696e-01 4.950027e-01 1.642022e-01 0 12 9 TRUE FALSE 102 TRUE 2.5074829 1.9530530 0.5480306 2.4788355 0.7702221 1.2100979 0.6714404 0.5889325 N 0.5492530 0.8924202 13773 129 184414 184415 1 36 Same - - 0.000000 0 0.000000 -0.11778304 1.652173 3.471939 1.0424998 200 Ribosomal protein L15 J ribosomal protein L15 1.496759 3.263330 1.1027567 1940 Transcriptional regulator/sugar kinase KG glucokinase (ROK family protein), conjectural 2.897501e-02 9 2.415355e-02 9.108602e-03 3.009013e-02 4.519590e-01 2.036413e-01 9 30 TRUE FALSE 101 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.7702221 0.7271808 0.6573932 0.5784676 U 0.4686274 0.5554237 13773 129 184415 184416 1 101 Divergent - + 0.000000 0 0.000000 -3.37083372 1.496759 3.263330 1.1027567 1940 Transcriptional regulator/sugar kinase KG glucokinase (ROK family protein), conjectural 1.479852 3.165856 1.0952465 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 2.491877e-04 30 2.858420e-04 1.291080e-03 3.266367e-02 1.755144e-01 1.451812e-02 30 38 TRUE FALSE 100 FALSE 0.4469764 0.1881260 0.5480306 0.4469764 0.7754515 0.4455208 0.5404755 0.6405817 U 0.4686274 0.5217494 13773 129 184416 184417 1 -17 Convergent + - 0.000000 0 0.000000 0.00000000 1.479852 3.165856 1.0952465 334 Glutamate dehydrogenase/leucine dehydrogenase E glutamate dehydrogenase 1.518403 3.300654 1.1145888 - - - conserved hypothetical protein part 2, authentic frameshift 0.000000e+00 0 1.486140e-03 1.907040e-03 5.238167e-02 2.217611e-01 6.144920e-02 38 0 FALSE FALSE 101 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5580296 0.6199051 U 0.4686274 0.6162291 13773 129 184417 184418 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.518403 3.300654 1.1145888 - - - conserved hypothetical protein part 2, authentic frameshift 1.522729 3.278875 1.0189847 121 Predicted glutamine amidotransferase R conserved hypothetical protein part 1, authentic frameshift 0.000000e+00 0 1.871849e-05 4.780212e-03 7.814930e-02 3.881991e-01 6.031303e-04 0 0 TRUE FALSE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6294088 0.6529329 U 0.4686274 0.6162291 13773 129 184418 184419 1 146 Same - - 0.000000 0 0.000000 0.00000000 1.522729 3.278875 1.0189847 121 Predicted glutamine amidotransferase R conserved hypothetical protein part 1, authentic frameshift 1.388011 2.960141 1.0368927 174 Glutamine synthetase E glutamine synthetase 0.000000e+00 0 1.814894e-02 -4.521418e-03 -3.484931e-02 -3.291890e-01 1.330544e+00 0 26 TRUE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4329986 0.4229102 U 0.4686274 0.6162291 13773 129 184419 184420 1 327 Divergent - + 0.000000 0 0.000000 0.00000000 1.388011 2.960141 1.0368927 174 Glutamine synthetase E glutamine synthetase 1.525243 3.194251 1.0713028 67 Glutamate synthase domain 1 E glutamate synthase subunit, conjectural 1.190151e-02 2 1.883262e-02 -4.680760e-03 -3.034285e-02 -3.363453e-01 1.362604e+00 E 26 2 TRUE FALSE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.6132969 0.4308323 0.4216139 Y 1.4497162 0.7118045 13773 129 184420 184421 1 -3 Same + + 2.856470 0 5.519058 5.51905803 1.525243 3.194251 1.0713028 67 Glutamate synthase domain 1 E glutamate synthase subunit, conjectural 1.593699 3.464907 1.1384760 69 Glutamate synthase domain 2 E glutamate synthase subunit, conjectural 1.242508e-01 2 4.686168e-03 1.050930e-02 1.811927e-01 5.555925e-01 4.262022e-02 E 2 2 FALSE FALSE 99 TRUE 2.8950318 1.7912907 0.5480306 2.8617306 0.6838149 1.0601895 0.7016080 0.6270113 Y 1.4497162 0.9052318 13773 129 184421 184422 1 -26 Convergent + - 0.000000 0 0.000000 0.00000000 1.593699 3.464907 1.1384760 69 Glutamate synthase domain 2 E glutamate synthase subunit, conjectural 1.609087 3.629184 1.0825689 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved within P. aerophilum 0.000000e+00 0 2.367978e-04 2.244076e-02 2.948449e-01 7.545813e-01 6.808775e-04 2 0 FALSE FALSE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7676068 0.6526075 U 0.4686274 0.6162291 13773 129 184422 184423 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.609087 3.629184 1.0825689 2250 Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN S conserved within P. aerophilum 1.519914 3.361954 1.1200731 75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase E aminotransferase, class-V 0.000000e+00 0 7.951757e-03 1.080540e-02 9.584997e-02 5.468177e-01 6.848886e-02 0 41 TRUE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6977079 0.6183298 U 0.4686274 0.6162291 13773 129 184423 184424 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.519914 3.361954 1.1200731 75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase E aminotransferase, class-V 1.480420 3.426500 1.1378221 - - - hypothetical protein 0.000000e+00 0 1.559758e-03 1.989008e-03 3.421008e-02 2.279597e-01 6.375334e-02 41 0 TRUE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5613553 0.6194066 U 0.4686274 0.6162291 13773 129 184424 184425 1 180 Same - - 0.000000 0 0.000000 0.00000000 1.480420 3.426500 1.1378221 - - - hypothetical protein 1.564119 3.438725 1.0956562 - - - hypothetical protein 0.000000e+00 0 7.005425e-03 3.272161e-03 8.912685e-02 2.903100e-01 1.781708e-01 0 0 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5896282 0.5854446 U 0.4686274 0.6162291 13773 129 184425 184426 1 48 Same - - 0.000000 0 0.000000 0.00000000 1.564119 3.438725 1.0956562 - - - hypothetical protein 1.518398 3.135700 1.0428241 - - - conserved within P. aerophilum 0.000000e+00 0 2.090440e-03 7.553166e-03 8.818295e-02 4.818298e-01 3.225098e-02 0 0 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6672490 0.6314500 U 0.4686274 0.6162291 13773 129 184426 184427 1 86 Same - - 0.000000 0 0.000000 0.00000000 1.518398 3.135700 1.0428241 - - - conserved within P. aerophilum 1.578096 3.523737 1.1311529 746 Molybdopterin-guanine dinucleotide biosynthesis protein A H molybdopterin-guanine dinucleotide biosynthesis protein A 0.000000e+00 0 3.563869e-03 8.489678e-03 1.493682e-01 5.010281e-01 4.454270e-02 0 0 TRUE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6728526 0.6261253 U 0.4686274 0.6162291 13773 129 184427 184428 1 51 Divergent - + 0.000000 0 0.000000 0.00000000 1.578096 3.523737 1.1311529 746 Molybdopterin-guanine dinucleotide biosynthesis protein A H molybdopterin-guanine dinucleotide biosynthesis protein A 1.447770 3.196108 1.1088351 1449 Alpha-amylase/alpha-mannosidase G pullulanase 0.000000e+00 0 1.698485e-02 -4.590586e-04 -2.536468e-02 5.041792e-02 5.772734e-01 0 0 0 TRUE FALSE 94 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187841 0.4802448 N 0.5492530 0.6245624 13773 129 184428 184429 1 32 Same + + 0.000000 0 0.000000 0.00000000 1.447770 3.196108 1.1088351 1449 Alpha-amylase/alpha-mannosidase G pullulanase 1.466083 3.230318 1.0862493 2182 Maltose-binding periplasmic proteins/domains G maltose ABC transporter, maltose binding protein 0.000000e+00 0 3.353866e-04 -5.322516e-05 2.063008e-02 1.399451e-02 2.773516e-02 G 0 20 FALSE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182347 0.6341446 Y 1.4497162 0.7118045 13773 129 184429 184430 1 1 Same + + 5.598422 0 8.411833 8.30338097 1.466083 3.230318 1.0862493 2182 Maltose-binding periplasmic proteins/domains G maltose ABC transporter, maltose binding protein 1.477883 3.506428 1.1581356 1175 ABC-type sugar transport systems, permease components G maltose ABC transporter, permease protein -3.777206e-02 14 1.392227e-04 3.891458e-04 2.652163e-02 7.924390e-02 1.433377e-02 G 20 14 FALSE FALSE 96 TRUE 2.7948173 1.8231938 0.5480306 2.7929181 0.7782928 0.5246514 0.5177863 0.6407068 Y 1.4497162 0.9096879 13773 129 184430 184431 1 -10 Same + + 11.056209 0 11.056209 10.44286798 1.477883 3.506428 1.1581356 1175 ABC-type sugar transport systems, permease components G maltose ABC transporter, permease protein 1.458940 3.605643 1.1919351 3833 ABC-type maltose transport systems, permease component G maltose ABC transporter, permease protein 5.083343e-02 14 3.588148e-04 1.999261e-04 2.143795e-02 5.789874e-02 3.280463e-02 G 14 24 FALSE FALSE 97 TRUE 2.6417794 1.8494343 0.5480306 2.7282488 0.7782928 0.8418369 0.5186503 0.6312229 Y 1.4497162 0.9139020 13773 129 184431 184432 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.458940 3.605643 1.1919351 3833 ABC-type maltose transport systems, permease component G maltose ABC transporter, permease protein 1.379263 2.853371 1.0930775 - - - hypothetical protein 0.000000e+00 0 6.348402e-03 -5.443841e-04 2.744018e-02 -9.803164e-02 5.702974e-01 24 0 FALSE FALSE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4923903 0.4815115 U 0.4686274 0.6162291 13773 129 184432 184433 1 41 Same - - 0.000000 0 0.000000 0.00000000 1.379263 2.853371 1.0930775 - - - hypothetical protein 1.491825 3.248776 1.0728819 - - - hypothetical protein 0.000000e+00 0 1.267004e-02 -2.916321e-03 -2.242159e-02 -2.669894e-01 1.086202e+00 0 0 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4480012 0.4339027 U 0.4686274 0.6162291 13773 129 184433 184434 1 25 Same - - 0.000000 0 0.000000 0.00000000 1.491825 3.248776 1.0728819 - - - hypothetical protein 1.485592 3.385946 1.1409496 501 Zn-dependent protease with chaperone function O heat shock protein, htpX homolog, conjectural 0.000000e+00 0 3.884682e-05 1.382723e-03 3.572362e-02 1.872755e-01 1.654485e-03 0 27 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5449334 0.6507995 U 0.4686274 0.6162291 13773 129 184434 184435 1 552 Divergent - + 0.000000 0 0.000000 0.00000000 1.485592 3.385946 1.1409496 501 Zn-dependent protease with chaperone function O heat shock protein, htpX homolog, conjectural 1.462474 3.190485 1.0247258 - - - hypothetical protein 0.000000e+00 0 5.344330e-04 3.789649e-04 2.251035e-02 8.397293e-02 4.389716e-02 27 0 TRUE FALSE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176852 0.6263686 U 0.4686274 0.6162291 13773 129 184435 184436 1 5 Same + + 0.000000 0 0.000000 0.00000000 1.462474 3.190485 1.0247258 - - - hypothetical protein 1.447970 3.166070 1.1249100 1910 Periplasmic molybdate-binding protein/domain P molybdenum cofactor biosynthesis protein (moaA) 0.000000e+00 0 2.103592e-04 -3.792633e-05 2.001216e-02 1.279885e-02 1.972483e-02 0 10 FALSE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184879 0.6377141 U 0.4686274 0.6162291 13773 129 184436 184437 1 1 Convergent + - 7.401231 0 9.991498 9.97347992 1.447970 3.166070 1.1249100 1910 Periplasmic molybdate-binding protein/domain P molybdenum cofactor biosynthesis protein (moaA) 1.506215 3.319689 1.1388802 303 Molybdopterin biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 1.982839e-03 10 3.392481e-03 -1.876347e-04 2.614655e-02 3.419466e-02 2.308128e-01 0 10 24 FALSE FALSE 97 FALSE 2.7376853 1.8393078 0.5480306 2.7601725 0.7739415 0.4965776 0.5175226 0.5706964 N 0.5492530 0.8745979 13773 129 184437 184438 1 -70 Divergent - + 0.000000 0 0.000000 0.00000000 1.506215 3.319689 1.1388802 303 Molybdopterin biosynthesis enzyme H molybdenum cofactor biosynthesis protein (moaA) 1.424211 3.193789 1.1178774 - - - hypothetical protein 0.000000e+00 0 6.724632e-03 -1.490152e-03 -2.441807e-03 -9.883091e-02 5.259867e-01 24 0 TRUE FALSE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4916052 0.4884610 U 0.4686274 0.6162291 13773 129 184438 184439 1 -29 Convergent + - 0.000000 0 0.000000 0.00000000 1.424211 3.193789 1.1178774 - - - hypothetical protein 1.469080 3.227631 1.0559735 121 Predicted glutamine amidotransferase R conserved hypothetical protein 0.000000e+00 0 2.013201e-03 -4.807655e-04 1.403464e-02 -4.746117e-02 1.960933e-01 0 4 FALSE FALSE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5071886 0.5808669 U 0.4686274 0.6162291 13773 129 184439 184440 1 0 Same - - 0.000000 0 0.000000 0.00000000 1.469080 3.227631 1.0559735 121 Predicted glutamine amidotransferase R conserved hypothetical protein 1.441673 2.994574 1.0187828 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family, putative 7.595820e-03 4 7.511553e-04 -1.719192e-04 1.817303e-02 1.401807e-03 6.531300e-02 4 6 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.7323301 0.5735148 0.5198503 0.6189979 U 0.4686274 0.6162291 13773 129 184440 184441 1 31 Same - - 0.000000 0 0.000000 0.00000000 1.441673 2.994574 1.0187828 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family, putative 1.596176 3.449104 1.0797043 - - - hypothetical protein 0.000000e+00 0 2.387113e-02 -1.407281e-03 5.727687e-02 4.625962e-03 7.322526e-01 6 0 TRUE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5195466 0.4614144 U 0.4686274 0.6162291 13773 129 184441 184442 1 228 Same - - 0.000000 0 0.000000 0.00000000 1.596176 3.449104 1.0797043 - - - hypothetical protein 1.486860 3.342699 1.0809355 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family, putative 0.000000e+00 0 1.194990e-02 5.135059e-03 3.073934e-02 3.661119e-01 1.900237e-01 0 32 TRUE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6181333 0.5828520 U 0.4686274 0.6162291 13773 129 184442 184443 1 75 Divergent - + 0.000000 0 0.000000 -0.80701540 1.486860 3.342699 1.0809355 1522 Transcriptional regulators K transcriptional regulatory protein, AsnC family, putative 1.477023 3.301517 1.0879652 1890 Ribosomal protein S3AE J ribosomal protein S3 5.477931e-02 11 9.677483e-05 9.090225e-04 2.983989e-02 1.425944e-01 8.062744e-03 0 32 11 TRUE FALSE 93 FALSE 0.4469764 0.2179197 0.5480306 0.4469764 0.7764261 0.8679653 0.5282879 0.6440495 N 0.5492530 0.5400140 13773 129 184443 184444 1 -3 Convergent + - 0.000000 0 0.000000 -0.74160252 1.477023 3.301517 1.0879652 1890 Ribosomal protein S3AE J ribosomal protein S3 1.424201 2.960642 0.9943893 1094 Predicted RNA-binding protein (contains KH domains) R conserved hypothetical protein 2.561589e-01 10 2.790094e-03 -6.969139e-04 1.279865e-02 -6.125895e-02 2.683606e-01 11 10 FALSE FALSE 94 FALSE 0.4469764 0.2217490 0.5480306 0.4469764 0.7739415 1.1936934 0.5035652 0.5545399 U 0.4686274 0.5324275 13773 129 184444 184445 1 45 Divergent - + 18.293529 0 20.490754 20.49075354 1.424201 2.960642 0.9943893 1094 Predicted RNA-binding protein (contains KH domains) R conserved hypothetical protein 1.445773 3.056302 1.0590086 1718 Serine/threonine protein kinase involved in cell cycle control TD conserved hypothetical protein 1.890957e-01 10 4.653202e-04 1.528210e-04 2.072708e-02 -7.009033e-03 4.885355e-02 10 11 TRUE FALSE 93 FALSE 2.4711213 1.9194271 0.5480306 2.5896816 0.7739415 1.1270741 0.5193871 0.6242586 U 0.4686274 0.8851350 13773 129 184445 184446 1 -29 Convergent + - 0.000000 0 0.000000 -0.22303471 1.445773 3.056302 1.0590086 1718 Serine/threonine protein kinase involved in cell cycle control TD conserved hypothetical protein 1.476672 3.224909 1.0680170 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C indolepyruvate ferredoxin oxidoreductase beta subunit -1.050550e-02 9 9.547465e-04 -1.420714e-04 2.061913e-02 1.278118e-02 8.685076e-02 11 9 FALSE FALSE 94 FALSE 0.4469764 0.2701025 0.5480306 0.4469764 0.7702221 0.5247367 0.5185094 0.6122969 U 0.4686274 0.5477293 13773 129 184446 184447 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.476672 3.224909 1.0680170 1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit C indolepyruvate ferredoxin oxidoreductase beta subunit 1.458104 3.223126 1.0948788 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C indolepyruvate ferredoxin oxidoreductase alpha subunit part 2, authentic frameshift 0.000000e+00 0 3.447527e-04 1.696528e-04 2.121291e-02 5.214721e-02 3.115780e-02 C 9 0 TRUE FALSE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187815 0.6322033 Y 1.4497162 0.7118045 13773 129 184447 184448 1 36 Same - - 0.000000 0 0.000000 0.00000000 1.458104 3.223126 1.0948788 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C indolepyruvate ferredoxin oxidoreductase alpha subunit part 2, authentic frameshift 1.510086 3.386617 1.1121394 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C indolepyruvate ferredoxin oxidoreductase alpha subunit part 1, authentic frameshift 0.000000e+00 0 2.702133e-03 3.939068e-04 3.397734e-02 8.843398e-02 1.666996e-01 C 0 0 TRUE FALSE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177457 0.5883689 Y 1.4497162 0.7118045 13773 129 184448 184449 1 84 Divergent - + 0.000000 0 0.000000 0.00000000 1.510086 3.386617 1.1121394 4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits C indolepyruvate ferredoxin oxidoreductase alpha subunit part 1, authentic frameshift 1.430055 2.835598 1.0196239 1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS K transcription associated protein, conjectural 0.000000e+00 0 6.405067e-03 -1.252418e-03 -1.498001e-03 -6.545848e-02 4.634025e-01 0 0 0 TRUE FALSE 91 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5023978 0.5009016 N 0.5492530 0.6245624 13773 129 184449 184450 1 120 Same + + 0.000000 0 0.000000 0.00000000 1.430055 2.835598 1.0196239 1594 DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS K transcription associated protein, conjectural 1.385896 3.024794 1.0365126 1259 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.949966e-03 1.397593e-03 4.681649e-02 6.305715e-02 1.833917e-01 0 7 FALSE FALSE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5183590 0.5843367 U 0.4686274 0.6162291 13773 129 184450 184451 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.385896 3.024794 1.0365126 1259 Uncharacterized conserved protein S conserved hypothetical protein 1.432213 2.949006 1.0287966 - - - hypothetical protein 0.000000e+00 0 2.145255e-03 1.256220e-03 2.546591e-02 4.802366e-02 2.078184e-01 7 0 FALSE FALSE 93 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187350 0.5771537 U 0.4686274 0.6162291 13773 129 184451 184452 1 -19 Same - - 0.000000 0 0.000000 0.00000000 1.432213 2.949006 1.0287966 - - - hypothetical protein 1.439861 3.092728 1.0758769 - - - hypothetical protein 0.000000e+00 0 5.848809e-05 2.211847e-04 2.272737e-02 9.482810e-04 6.008332e-03 0 0 TRUE FALSE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199062 0.6454790 U 0.4686274 0.6162291 13773 129 184452 184453 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.439861 3.092728 1.0758769 - - - hypothetical protein 1.468560 3.268688 1.0724256 184 Ribosomal protein S15P/S13E J ribosomal protein S13 0.000000e+00 0 8.236753e-04 -1.979791e-04 1.883360e-02 -2.729400e-03 7.010506e-02 0 12 TRUE FALSE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198933 0.6177812 U 0.4686274 0.6162291 13773 129 184453 184454 1 -61 Divergent - + 0.000000 0 0.000000 0.00000000 1.468560 3.268688 1.0724256 184 Ribosomal protein S15P/S13E J ribosomal protein S13 1.403645 3.044916 1.0509100 500 SAM-dependent methyltransferases QR conserved hypothetical protein 0.000000e+00 0 4.214028e-03 -8.197183e-04 1.619459e-02 -9.669875e-02 4.028304e-01 12 0 TRUE FALSE 90 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4932647 0.5119762 U 0.4686274 0.6162291 13773 129 184454 184455 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.403645 3.044916 1.0509100 500 SAM-dependent methyltransferases QR conserved hypothetical protein 1.500280 3.303510 1.1084920 1899 Deoxyhypusine synthase O deoxyhypusine synthase 0.000000e+00 0 9.338408e-03 -2.334277e-03 -6.275674e-03 -1.939818e-01 7.925509e-01 0 17 FALSE FALSE 91 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4660927 0.4565008 U 0.4686274 0.6162291 13773 129 184455 184456 1 2 Same + + 0.000000 0 0.000000 0.00000000 1.500280 3.303510 1.1084920 1899 Deoxyhypusine synthase O deoxyhypusine synthase 1.454095 3.459131 1.1660987 472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase M UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 0.000000e+00 0 2.133133e-03 1.320774e-04 1.623111e-02 6.140149e-02 1.514004e-01 0 17 0 FALSE FALSE 92 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184463 0.5927845 N 0.5492530 0.6245624 13773 129 184456 184457 1 18 Same + + 0.000000 0 0.000000 0.00000000 1.454095 3.459131 1.1660987 472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase M UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 1.391093 3.466085 1.1290702 - - - hypothetical protein 0.000000e+00 0 3.969250e-03 -1.629110e-04 2.804834e-02 -5.964452e-02 3.788436e-01 0 0 FALSE FALSE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5037935 0.5175511 U 0.4686274 0.6162291 13773 129 184457 184458 1 118 Same + + 0.000000 0 0.000000 0.00000000 1.391093 3.466085 1.1290702 - - - hypothetical protein 1.418430 3.147212 1.0643129 1159 GTPase R conserved within P. aerophilum 0.000000e+00 0 7.473326e-04 1.987676e-03 3.750349e-02 1.151101e-01 6.889114e-02 0 0 FALSE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5211120 0.6181692 U 0.4686274 0.6162291 13773 129 184458 184459 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.418430 3.147212 1.0643129 1159 GTPase R conserved within P. aerophilum 1.449004 3.221455 1.1100557 - - - conserved within P. aerophilum 0.000000e+00 0 9.347651e-04 7.874871e-05 1.891362e-02 -1.713267e-02 9.376850e-02 0 0 FALSE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5161866 0.6094409 U 0.4686274 0.6162291 13773 129 184459 184460 1 -31 Convergent + - 0.000000 0 0.000000 0.00000000 1.449004 3.221455 1.1100557 - - - conserved within P. aerophilum 1.437739 3.215331 1.1088902 561 Predicted hydrolases of the HAD superfamily R conserved hypothetical protein 0.000000e+00 0 1.268963e-04 3.261912e-05 2.157802e-02 -2.940260e-03 1.290133e-02 0 8 FALSE FALSE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5198717 0.6415107 U 0.4686274 0.6162291 13773 129 184460 184461 1 171 Same - - 0.000000 0 0.000000 0.00000000 1.437739 3.215331 1.1088902 561 Predicted hydrolases of the HAD superfamily R conserved hypothetical protein 1.364633 3.107985 1.0389980 - - - hypothetical protein 0.000000e+00 0 5.344522e-03 1.184608e-03 5.323070e-02 2.787122e-02 4.335965e-01 8 0 TRUE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173817 0.5065808 U 0.4686274 0.6162291 13773 129 184461 184462 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.364633 3.107985 1.0389980 - - - hypothetical protein 1.423513 3.038676 1.0849705 491 Zn-dependent hydrolases, including glyoxylases R hypothetical protein 0.000000e+00 0 3.466920e-03 2.418829e-03 3.187753e-02 1.313163e-01 2.604681e-01 0 0 TRUE FALSE 94 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5247837 0.5576556 U 0.4686274 0.6162291 13773 129 184462 184463 1 -24 Convergent + - 0.000000 0 0.000000 0.00000000 1.423513 3.038676 1.0849705 491 Zn-dependent hydrolases, including glyoxylases R hypothetical protein 1.365044 3.026124 1.0867107 1833 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 3.418649e-03 2.407361e-03 6.584620e-02 1.308834e-01 2.581233e-01 0 2 FALSE FALSE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5245418 0.5591829 U 0.4686274 0.6162291 13773 129 184463 184464 1 61 Same - - 0.000000 0 0.000000 0.00000000 1.365044 3.026124 1.0867107 1833 Uncharacterized conserved protein S conserved hypothetical protein 1.520521 3.347956 1.1406227 846 NAD-dependent protein deacetylases, SIR2 family K conserved hypothetical protein 1.022897e-02 2 2.417298e-02 -5.969105e-03 -5.585414e-02 -4.364560e-01 1.750595e+00 2 23 TRUE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6838149 0.5994940 0.4134977 0.4114287 U 0.4686274 0.6162291 13773 129 184464 184465 1 68 Same - - 0.000000 0 0.000000 0.00000000 1.520521 3.347956 1.1406227 846 NAD-dependent protein deacetylases, SIR2 family K conserved hypothetical protein 1.433895 2.686939 1.1798588 - - - hypothetical protein 0.000000e+00 0 7.503948e-03 -1.209561e-03 -4.762805e-03 -4.234634e-02 4.824011e-01 23 0 TRUE FALSE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5084194 0.4960755 U 0.4686274 0.6162291 13773 129 184465 184466 1 536 Divergent - + 0.000000 0 0.000000 0.00000000 1.433895 2.686939 1.1798588 - - - hypothetical protein 1.514628 3.262009 1.0638383 - - - hypothetical protein 0.000000e+00 0 6.517689e-03 -1.106447e-03 1.717788e-02 -3.991026e-02 4.335965e-01 0 0 TRUE FALSE 92 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5090922 0.5065808 U 0.4686274 0.6162291 13773 129 184466 184467 1 350 Same + + 0.000000 0 0.000000 0.00000000 1.514628 3.262009 1.0638383 - - - hypothetical protein 1.594776 3.696163 1.1789319 - - - hypothetical protein 0.000000e+00 0 6.423807e-03 9.066816e-03 1.688041e-01 5.074952e-01 7.174011e-02 0 0 FALSE FALSE 93 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6757000 0.6173235 U 0.4686274 0.6162291 13773 129 184467 184468 1 -24 Same + + 0.000000 0 0.000000 0.00000000 1.594776 3.696163 1.1789319 - - - hypothetical protein 1.498709 3.617785 1.1506403 - - - conserved hypothetical protein 0.000000e+00 0 9.228938e-03 6.784338e-03 5.353827e-02 4.284051e-01 1.295558e-01 0 0 FALSE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6466317 0.5982270 U 0.4686274 0.6162291 13773 129 184468 184469 1 92 Same + + 0.000000 0 0.000000 0.00000000 1.498709 3.617785 1.1506403 - - - conserved hypothetical protein 1.847169 4.221520 1.1099943 - - - hypothetical protein 0.000000e+00 0 1.214241e-01 1.872654e-02 6.317928e-01 4.965517e-01 2.465584e-01 0 0 FALSE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6721456 0.5636133 U 0.4686274 0.6162291 13773 129 184469 184470 1 224 Same + + 0.000000 0 0.000000 0.00000000 1.847169 4.221520 1.1099943 - - - hypothetical protein 1.395453 3.174057 1.1277048 1750 Archaeal serine proteases R conserved hypothetical protein 0.000000e+00 0 2.040472e-01 -2.213974e-02 -6.279640e-01 -4.614111e-01 2.128509e+00 0 3 FALSE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4104216 0.4069224 U 0.4686274 0.6162291 13773 129 184470 184471 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.395453 3.174057 1.1277048 1750 Archaeal serine proteases R conserved hypothetical protein 1.503207 3.532179 1.1561023 - - - hypothetical protein 0.000000e+00 0 1.161091e-02 -2.898471e-03 -1.428117e-02 -2.433348e-01 9.771087e-01 3 0 FALSE FALSE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4529721 0.4414343 U 0.4686274 0.6162291 13773 129 184471 184472 1 142 Divergent - + 0.000000 0 0.000000 0.00000000 1.503207 3.532179 1.1561023 - - - hypothetical protein 1.417471 2.954517 1.0463351 - - - hypothetical protein 0.000000e+00 0 7.350560e-03 -1.757607e-03 -3.708344e-03 -1.265019e-01 5.866408e-01 0 0 TRUE FALSE 96 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4829501 0.4787644 U 0.4686274 0.6162291 13773 129 184472 184473 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.417471 2.954517 1.0463351 - - - hypothetical protein 1.387701 3.047173 1.0314259 1961 Site-specific recombinases, DNA invertase Pin homologs L resolvase, conjectural 0.000000e+00 0 8.862440e-04 2.160515e-03 5.337866e-02 1.253922e-01 7.803940e-02 0 4 FALSE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5230952 0.6154327 U 0.4686274 0.6162291 13773 129 184473 184474 1 75 Convergent + - 0.000000 0 0.000000 -0.26236426 1.387701 3.047173 1.0314259 1961 Site-specific recombinases, DNA invertase Pin homologs L resolvase, conjectural 1.417667 3.082490 1.0584816 2236 Predicted phosphoribosyltransferases R xanthine-guanine phosphoribosyltransferase, conjectural 1.448039e-03 4 8.979666e-04 2.148016e-03 3.843956e-02 1.237948e-01 7.976398e-02 4 12 FALSE FALSE 98 FALSE 0.4469764 0.2622094 0.5480306 0.4469764 0.7323301 0.4819640 0.5227417 0.6145887 U 0.4686274 0.5452369 13773 129 184474 184475 1 48 Same - - 0.000000 0 0.000000 0.00000000 1.417667 3.082490 1.0584816 2236 Predicted phosphoribosyltransferases R xanthine-guanine phosphoribosyltransferase, conjectural 1.587012 3.460911 1.0172648 - - - conserved within P. aerophilum 0.000000e+00 0 2.867752e-02 -4.573799e-03 1.107908e-02 -2.006645e-01 1.169319e+00 12 0 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4645295 0.4297294 U 0.4686274 0.6162291 13773 129 184475 184476 1 -7 Same - - 0.000000 0 0.000000 0.00000000 1.587012 3.460911 1.0172648 - - - conserved within P. aerophilum 1.491405 3.179721 0.9761674 - - - hypothetical protein 0.000000e+00 0 9.140731e-03 5.426368e-03 4.154196e-02 3.799679e-01 1.544013e-01 0 0 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6247145 0.5918248 U 0.4686274 0.6162291 13773 129 184476 184477 1 316 Divergent - + 0.000000 0 0.000000 0.00000000 1.491405 3.179721 0.9761674 - - - hypothetical protein 1.392485 3.038334 1.0713044 504 CTP synthase (UTP-ammonia lyase) F CTP synthase (pyrG) 0.000000e+00 0 9.785190e-03 -2.357029e-03 -2.074411e-03 -2.160873e-01 8.651998e-01 0 70 TRUE FALSE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4599820 0.4487631 U 0.4686274 0.6162291 13773 129 184477 184478 1 -10 Convergent + - 0.000000 0 0.000000 -0.13353139 1.392485 3.038334 1.0713044 504 CTP synthase (UTP-ammonia lyase) F CTP synthase (pyrG) 1.502449 3.541712 1.1204014 838 NADH:ubiquinone oxidoreductase subunit 3 (chain A) C NADH-ubiquinone oxidoreductase subunit 7.562104e-04 1 1.209214e-02 -3.007620e-03 -1.662103e-02 -2.499545e-01 1.001536e+00 0 70 1 FALSE FALSE 96 FALSE 0.4469764 0.2828094 0.5480306 0.4469764 0.6329203 0.4649491 0.4521609 0.4391251 N 0.5492530 0.5604716 13773 129 184478 184479 1 47 Divergent - + 0.000000 0 0.000000 0.00000000 1.502449 3.541712 1.1204014 838 NADH:ubiquinone oxidoreductase subunit 3 (chain A) C NADH-ubiquinone oxidoreductase subunit 1.446735 3.585552 1.2116785 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved within P. aerophilum 0.000000e+00 0 3.104026e-03 -2.378088e-04 1.139249e-02 2.679512e-02 2.206043e-01 1 0 TRUE FALSE 95 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5173824 0.5741897 U 0.4686274 0.6162291 13773 129 184479 184480 1 23 Same + + 0.000000 0 0.000000 0.00000000 1.446735 3.585552 1.2116785 697 Permeases of the drug/metabolite transporter (DMT) superfamily GER conserved within P. aerophilum 1.536478 3.340087 1.1301968 496 Predicted acid phosphatase R surE stationary-phase survival protein homolog 0.000000e+00 0 8.053763e-03 -3.963091e-04 3.443349e-02 3.606884e-02 4.225499e-01 0 2 FALSE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177197 0.5083822 U 0.4686274 0.6162291 13773 129 184480 184481 1 130 Same + + 0.000000 0 0.000000 0.00000000 1.536478 3.340087 1.1301968 496 Predicted acid phosphatase R surE stationary-phase survival protein homolog 1.467782 3.182045 1.0366393 - - - hypothetical protein 0.000000e+00 0 4.719071e-03 1.394496e-03 1.934003e-02 1.728074e-01 2.071193e-01 2 0 FALSE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5391809 0.5774877 U 0.4686274 0.6162291 13773 129 184481 184482 1 9 Same + + 0.000000 0 0.000000 0.00000000 1.467782 3.182045 1.0366393 - - - hypothetical protein 1.417721 3.154864 1.0944107 1199 Rad3-related DNA helicases KL hypothetical protein 0.000000e+00 0 2.506156e-03 -5.518668e-04 1.648228e-02 -5.823270e-02 2.330303e-01 0 0 FALSE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5043201 0.5695312 U 0.4686274 0.6162291 13773 129 184482 184483 1 22 Same + + 0.000000 0 0.000000 0.00000000 1.417721 3.154864 1.0944107 1199 Rad3-related DNA helicases KL hypothetical protein 1.441285 3.277967 1.0477744 433 Predicted ATPase R conserved hypothetical protein 0.000000e+00 0 5.552636e-04 3.403583e-04 2.209741e-02 3.628206e-04 5.515108e-02 0 0 FALSE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199291 0.6221915 U 0.4686274 0.6162291 13773 129 184483 184484 1 410 Convergent + - 0.000000 0 0.000000 0.00000000 1.441285 3.277967 1.0477744 433 Predicted ATPase R conserved hypothetical protein 1.471933 3.174599 1.0523486 675 Transposase and inactivated derivatives L paREP12, internal deletion 0.000000e+00 0 9.393029e-04 -2.076191e-04 1.912208e-02 -4.334999e-04 8.063333e-02 0 0 FALSE FALSE 100 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199833 0.6142303 U 0.4686274 0.6162291 13773 129 184484 184485 1 142 Same - - 0.000000 0 0.000000 0.00000000 1.471933 3.174599 1.0523486 675 Transposase and inactivated derivatives L paREP12, internal deletion 1.297072 2.938721 0.8081866 - - - hypothetical protein 0.000000e+00 0 3.057638e-02 -3.169756e-03 4.308297e-02 -2.683364e-01 1.519156e+00 0 0 TRUE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4474900 0.4165262 U 0.4686274 0.6162291 13773 129 184485 184486 1 84 Same - - 0.000000 0 0.000000 0.00000000 1.297072 2.938721 0.8081866 - - - hypothetical protein 1.404995 3.151734 0.9898241 - - - hypothetical protein 0.000000e+00 0 1.164752e-02 7.160089e-03 4.944394e-02 3.448998e-01 3.446943e-01 0 0 TRUE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6106487 0.5259852 U 0.4686274 0.6162291 13773 129 184486 184487 1 49 Same - - 0.000000 0 0.000000 0.00000000 1.404995 3.151734 0.9898241 - - - hypothetical protein 1.367187 2.998763 0.8920434 - - - hypothetical protein 0.000000e+00 0 1.429448e-03 3.906909e-03 7.895805e-02 2.482276e-01 1.029115e-01 0 0 TRUE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5688795 0.6052131 U 0.4686274 0.6162291 13773 129 184487 184488 1 221 Same - - 0.000000 0 0.000000 0.00000000 1.367187 2.998763 0.8920434 - - - hypothetical protein 1.277446 2.839537 0.8949825 - - - hypothetical protein 0.000000e+00 0 8.053462e-03 1.464724e-02 2.508297e-01 6.649140e-01 8.326967e-02 0 0 TRUE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7417685 0.6130924 U 0.4686274 0.6162291 13773 129 184488 184489 1 109 Same - - 0.000000 0 0.000000 0.00000000 1.277446 2.839537 0.8949825 - - - hypothetical protein 1.267787 2.911802 0.8166724 - - - hypothetical protein 0.000000e+00 0 9.329838e-05 3.193755e-02 4.029310e-01 9.537151e-01 7.126832e-05 0 0 TRUE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.8119180 0.6552829 U 0.4686274 0.6162291 13773 129 184489 184490 1 165 Same - - 0.000000 0 0.000000 0.00000000 1.267787 2.911802 0.8166724 - - - hypothetical protein 1.362355 3.094657 1.0740223 - - - hypothetical protein 0.000000e+00 0 8.942987e-03 1.634792e-02 1.464055e-01 6.977852e-01 7.256470e-02 0 0 TRUE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7509780 0.6171587 U 0.4686274 0.6162291 13773 129 184490 184491 1 324 Divergent - + 0.000000 0 0.000000 0.00000000 1.362355 3.094657 1.0740223 - - - hypothetical protein 1.473073 3.298483 1.0341956 - - - hypothetical protein 0.000000e+00 0 1.225865e-02 -1.930398e-03 -2.077212e-02 -2.091172e-01 1.010773e+00 0 0 TRUE FALSE 93 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4619153 0.4386428 U 0.4686274 0.6162291 13773 129 184491 184492 1 358 Same + + 0.000000 0 0.000000 0.00000000 1.473073 3.298483 1.0341956 - - - hypothetical protein 1.414157 3.080967 1.0637987 - - - paREP2b 0.000000e+00 0 3.471099e-03 -8.072858e-04 1.362597e-02 -7.918028e-02 3.173243e-01 0 0 FALSE FALSE 94 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4982296 0.5362123 U 0.4686274 0.6162291 13773 129 184492 184493 1 7 Same + + 0.000000 0 0.000000 0.00000000 1.414157 3.080967 1.0637987 - - - paREP2b 1.497281 3.323162 1.1430746 - - - paREP2b 0.000000e+00 0 6.909569e-03 -1.708674e-03 2.585958e-03 -1.314848e-01 5.737801e-01 0 0 FALSE FALSE 95 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4811310 0.4809145 U 0.4686274 0.6162291 13773 129 184493 184494 1 61 Same + + 0.000000 0 0.000000 0.00000000 1.497281 3.323162 1.1430746 - - - paREP2b 1.386259 3.089411 1.0077108 - - - hypothetical protein 0.000000e+00 0 1.232594e-02 -2.988886e-03 -8.783077e-03 -2.622203e-01 1.051294e+00 0 0 FALSE FALSE 96 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4491837 0.4359569 U 0.4686274 0.6162291 13773 129 184494 184495 1 29 Same + + 0.000000 0 0.000000 0.00000000 1.386259 3.089411 1.0077108 - - - hypothetical protein 1.373655 3.116344 1.0639878 501 Zn-dependent protease with chaperone function O heat shock protein, htpX homolog, conjectural 0.000000e+00 0 1.588610e-04 5.063372e-03 8.451309e-02 3.422057e-01 9.954005e-03 0 0 FALSE FALSE 97 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6092902 0.6428219 U 0.4686274 0.6162291 13773 129 184495 184496 1 -16 Same + + 0.000000 0 0.000000 0.00000000 1.373655 3.116344 1.0639878 501 Zn-dependent protease with chaperone function O heat shock protein, htpX homolog, conjectural 1.474565 3.187234 1.0022631 - - - hypothetical protein 0.000000e+00 0 1.018277e-02 -1.801327e-03 -1.430710e-02 -1.984793e-01 8.998044e-01 0 0 FALSE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4649583 0.4463809 U 0.4686274 0.6162291 13773 129 184496 184497 1 86 Convergent + - 0.000000 0 0.000000 0.00000000 1.474565 3.187234 1.0022631 - - - hypothetical protein 1.446098 3.342216 1.0732317 - - - hypothetical protein 0.000000e+00 0 8.103765e-04 -1.227019e-04 1.801069e-02 1.291311e-02 7.297876e-02 0 0 FALSE FALSE 99 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5184450 0.6169600 U 0.4686274 0.6162291 13773 129 184497 184498 1 186 Divergent - + 0.000000 0 0.000000 0.00000000 1.446098 3.342216 1.0732317 - - - hypothetical protein 1.439498 3.145241 1.0751773 434 Predicted TIM-barrel enzyme R conserved hypothetical protein 0.000000e+00 0 4.355469e-05 6.298721e-05 2.176226e-02 -6.043083e-04 3.138751e-03 0 13 TRUE FALSE 98 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199862 0.6484515 U 0.4686274 0.6162291 13773 129 184498 184499 1 -8 Convergent + - 0.000000 0 0.000000 -0.75154502 1.439498 3.145241 1.0751773 434 Predicted TIM-barrel enzyme R conserved hypothetical protein 1.417258 2.961320 1.0408604 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ mannose-1-phosphate guanyltransferase 5.239782e-02 13 4.946088e-04 4.060292e-04 2.808477e-02 3.536322e-03 5.195461e-02 13 21 FALSE FALSE 99 FALSE 0.4469764 0.2212749 0.5480306 0.4469764 0.7781369 0.8494258 0.5196730 0.6232413 U 0.4686274 0.5322771 13773 129 184499 184500 1 8 Same - - 0.000000 0 0.000000 0.00000000 1.417258 2.961320 1.0408604 1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translati MJ mannose-1-phosphate guanyltransferase 1.309528 2.893604 1.0246957 - - - hypothetical protein 0.000000e+00 0 1.160581e-02 4.842520e-03 1.255081e-01 2.242773e-01 4.654946e-01 21 0 TRUE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5591222 0.5002274 U 0.4686274 0.6162291 13773 129 184500 184501 1 75 Divergent - + 0.000000 0 0.000000 0.00000000 1.309528 2.893604 1.0246957 - - - hypothetical protein 1.406191 3.128289 1.1033615 - - - hypothetical protein 0.000000e+00 0 9.343776e-03 6.412546e-03 4.979438e-02 3.229309e-01 3.313094e-01 0 0 TRUE FALSE 97 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6013132 0.5307106 U 0.4686274 0.6162291 13773 129 184501 184502 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.406191 3.128289 1.1033615 - - - hypothetical protein 1.387544 2.958596 0.9967840 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR HIT family protein 0.000000e+00 0 3.477186e-04 2.886086e-03 5.964669e-02 1.822349e-01 2.981784e-02 0 7 FALSE FALSE 98 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5428240 0.6331508 U 0.4686274 0.6162291 13773 129 184502 184503 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.387544 2.958596 0.9967840 537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases FGR HIT family protein 1.405621 3.117972 1.0929542 - - - hypothetical protein 0.000000e+00 0 3.267858e-04 2.922480e-03 4.987576e-02 1.858395e-01 2.748012e-02 7 0 FALSE FALSE 99 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5446288 0.6342472 U 0.4686274 0.6162291 13773 129 184503 184504 1 6 Same + + 0.000000 0 0.000000 0.00000000 1.405621 3.117972 1.0929542 - - - hypothetical protein 1.387602 3.171204 1.1024636 1412 Uncharacterized proteins of PilT N-term./Vapc superfamily R conserved hypothetical protein 0.000000e+00 0 3.247024e-04 2.919838e-03 5.989093e-02 1.855662e-01 2.722627e-02 0 5 FALSE FALSE 100 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5443252 0.6344003 U 0.4686274 0.6162291 13773 129 184504 184505 1 86 Same + + 5.174893 0 7.372118 7.10226548 1.387602 3.171204 1.1024636 1412 Uncharacterized proteins of PilT N-term./Vapc superfamily R conserved hypothetical protein 1.452845 3.137839 1.0590329 1095 DNA-directed RNA polymerase, subunit E' K DNA-directed RNA polymerase subunit E' (rpoE1) 1.371616e-01 5 4.256763e-03 -9.266400e-05 9.325508e-03 -5.878930e-02 4.018567e-01 5 12 FALSE FALSE 101 TRUE 2.8105485 1.8111795 0.5480306 2.8192517 0.7448207 1.0738329 0.5040955 0.5122596 U 0.4686274 0.8655276 13773 129 184505 184506 1 -3 Same + + 21.712468 0 34.769166 34.76916632 1.452845 3.137839 1.0590329 1095 DNA-directed RNA polymerase, subunit E' K DNA-directed RNA polymerase subunit E' (rpoE1) 1.347898 2.879902 1.0271648 2093 DNA-directed RNA polymerase, subunit E'' K DNA-directed RNA polymerase subunit E'' (rpoE2) 3.229691e-01 10 1.101407e-02 -1.503386e-04 4.617592e-02 -8.935281e-02 8.187264e-01 K 12 10 FALSE FALSE 102 TRUE 2.3237071 2.0000141 0.5480306 2.3514976 0.7739415 1.2322996 0.4954503 0.4531269 Y 1.4497162 0.9304439 13773 129 184506 184507 1 -27 Convergent + - 0.000000 0 0.000000 0.00000000 1.347898 2.879902 1.0271648 2093 DNA-directed RNA polymerase, subunit E'' K DNA-directed RNA polymerase subunit E'' (rpoE2) 1.477362 3.323140 1.0954477 - - - hypothetical protein 0.000000e+00 0 1.676103e-02 -2.687677e-03 -3.617615e-02 -2.692741e-01 1.281431e+00 10 0 FALSE FALSE 103 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4471478 0.4248766 U 0.4686274 0.6162291 13773 129 184507 184508 1 45 Divergent - + 0.000000 0 0.000000 0.00000000 1.477362 3.323140 1.0954477 - - - hypothetical protein 1.388358 2.956561 1.0585255 13 Alanyl-tRNA synthetase J alanyl-tRNA synthetase 0.000000e+00 0 7.921748e-03 -1.636964e-03 9.975785e-03 -1.745585e-01 7.283175e-01 0 69 TRUE FALSE 102 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4718414 0.4619884 U 0.4686274 0.6162291 13773 129 184508 184509 1 -3 Same + + 0.000000 0 0.000000 -0.50304325 1.388358 2.956561 1.0585255 13 Alanyl-tRNA synthetase J alanyl-tRNA synthetase 1.348779 2.966397 1.0169133 1308 Transcription factor homologous to NACalpha-BTF3 K conserved hypothetical protein 5.924755e-03 6 1.566473e-03 6.468276e-03 1.130160e-01 4.034942e-01 7.422802e-02 0 69 6 FALSE FALSE 103 TRUE 0.4469764 0.2355917 0.5480306 0.4469764 0.7537284 0.5552173 0.6366355 0.6165928 N 0.5492530 0.5456018 13773 129 184509 184510 1 48 Same + + 0.000000 0 0.000000 -0.50304325 1.348779 2.966397 1.0169133 1308 Transcription factor homologous to NACalpha-BTF3 K conserved hypothetical protein 1.370248 2.947173 1.0258334 197 Ribosomal protein L16/L10E J ribosomal protein L10 1.689996e-01 6 4.608999e-04 8.326624e-03 1.080764e-01 5.168826e-01 1.642646e-02 0 6 12 FALSE FALSE 104 TRUE 0.4469764 0.2355917 0.5480306 0.4469764 0.7537284 1.1107342 0.6818607 0.6394805 N 0.5492530 0.5456018 13773 129 184510 184511 1 -25 Same + + 0.000000 0 0.000000 -0.26504093 1.370248 2.947173 1.0258334 197 Ribosomal protein L16/L10E J ribosomal protein L10 1.436208 3.182042 1.0856177 4879 Uncharacterized protein conserved in archaea S conserved hypothetical protein 7.846874e-02 3 4.350755e-03 1.232190e-03 1.900884e-02 3.331470e-02 3.685226e-01 12 3 FALSE FALSE 105 TRUE 0.4469764 0.2605979 0.5480306 0.4469764 0.7136133 0.9433797 0.5175102 0.5189918 U 0.4686274 0.5447277 13773 129 184511 184512 1 4 Convergent + - 0.000000 0 0.000000 0.00000000 1.436208 3.182042 1.0856177 4879 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.446472 3.255866 1.0988950 725 ABC-type molybdate transport system, periplasmic component P hypothetical protein 0.000000e+00 0 1.053446e-04 7.472894e-05 2.108738e-02 -2.371291e-03 9.499891e-03 3 0 FALSE FALSE 106 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5199032 0.6431205 U 0.4686274 0.6162291 13773 129 184512 184513 1 154 Divergent - + 0.000000 0 0.000000 0.00000000 1.446472 3.255866 1.0988950 725 ABC-type molybdate transport system, periplasmic component P hypothetical protein 1.426247 3.574479 1.1960691 555 ABC-type sulfate transport system, permease component O sulfate ABC transporter, permease protein, putative 0.000000e+00 0 4.090331e-04 1.237485e-04 2.372885e-02 -7.437232e-03 4.230393e-02 0 0 1 TRUE FALSE 105 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5192999 0.6271652 N 0.5492530 0.6245624 13773 129 184513 184514 1 -15 Same + + 0.000000 0 0.000000 0.00000000 1.426247 3.574479 1.1960691 555 ABC-type sulfate transport system, permease component O sulfate ABC transporter, permease protein, putative 1.398169 3.117203 1.0303856 3839 ABC-type sugar transport systems, ATPase components G ABC transporter ATP-binding protein, putative 0.000000e+00 0 7.883862e-04 1.338361e-03 4.197433e-02 6.961737e-02 7.803940e-02 0 1 0 FALSE FALSE 106 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5181128 0.6154327 N 0.5492530 0.6245624 13773 129 184514 184515 1 -5 Convergent + - 0.000000 0 0.000000 0.00000000 1.398169 3.117203 1.0303856 3839 ABC-type sugar transport systems, ATPase components G ABC transporter ATP-binding protein, putative 1.414256 3.173078 1.0830479 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E conserved hypothetical protein 0.000000e+00 0 2.587923e-04 1.976580e-03 4.015689e-02 1.170379e-01 2.929010e-02 0 0 2 FALSE FALSE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5215141 0.6334684 N 0.5492530 0.6245624 13773 129 184515 184516 1 73 Divergent - + 0.000000 0 0.000000 -0.05918887 1.414256 3.173078 1.0830479 1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases E conserved hypothetical protein 1.376129 3.007808 1.0297151 1938 Archaeal enzymes of ATP-grasp superfamily R conserved hypothetical protein 1.349135e-02 2 1.453686e-03 2.795087e-03 6.430182e-02 1.658208e-01 1.251737e-01 2 8 TRUE FALSE 106 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6838149 0.6281588 0.5369217 0.5995746 U 0.4686274 0.5589164 13773 129 184516 184517 1 36 Same + + 0.000000 0 0.000000 -0.69470386 1.376129 3.007808 1.0297151 1938 Archaeal enzymes of ATP-grasp superfamily R conserved hypothetical protein 1.406676 3.038932 1.0053241 94 Ribosomal protein L5 J ribosomal protein L5 2.254926e-01 8 9.331671e-04 3.365548e-03 5.078096e-02 2.129939e-01 7.718418e-02 8 13 FALSE FALSE 107 TRUE 0.4469764 0.2259572 0.5480306 0.4469764 0.7652913 1.1551773 0.5544965 0.6158124 U 0.4686274 0.5337621 13773 129 184517 184518 1 123 Same + + 0.000000 0 0.000000 -0.33826347 1.406676 3.038932 1.0053241 94 Ribosomal protein L5 J ribosomal protein L5 1.426197 3.129232 1.0852889 622 Predicted phosphoesterase R conserved hypothetical protein 6.991221e-02 5 3.810515e-04 1.126671e-03 3.044531e-02 5.502562e-02 3.336300e-02 13 5 FALSE FALSE 108 TRUE 0.4469764 0.2498620 0.5480306 0.4469764 0.7448207 0.9146962 0.5187390 0.6308211 U 0.4686274 0.5413334 13773 129 184518 184519 1 -3 Same + + 0.000000 0 0.000000 -0.11778304 1.426197 3.129232 1.0852889 622 Predicted phosphoesterase R conserved hypothetical protein 1.378533 3.138204 1.1046136 144 tRNA and rRNA cytosine-C5-methylases J sun family protein 5.190299e-03 5 2.271815e-03 1.835760e-03 5.407073e-02 9.540237e-02 1.886879e-01 5 6 FALSE FALSE 109 TRUE 0.4469764 0.2945188 0.5480306 0.4469764 0.7448207 0.5453500 0.5180357 0.5831776 U 0.4686274 0.5554237 13773 129 184519 184520 1 -10 Convergent + - 0.000000 0 0.000000 0.00000000 1.378533 3.138204 1.1046136 144 tRNA and rRNA cytosine-C5-methylases J sun family protein 1.474857 3.344690 1.1353321 2407 L-fucose isomerase and related proteins G conserved hypothetical protein 1.150801e-03 1 9.278219e-03 -1.709578e-03 -1.133401e-02 -1.866965e-01 8.256853e-01 0 6 1 FALSE FALSE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4759583 0.4683225 0.4524920 N 0.5492530 0.6245624 13773 129 184520 184521 1 24 Same - - 0.000000 0 0.000000 0.00000000 1.474857 3.344690 1.1353321 2407 L-fucose isomerase and related proteins G conserved hypothetical protein 1.425384 3.246338 1.1056420 2848 Uncharacterized conserved protein S conserved hypothetical protein 3.554731e-03 1 2.447569e-03 -6.102733e-04 1.392193e-02 -5.299772e-02 2.330303e-01 1 17 TRUE FALSE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5281729 0.5058529 0.5695312 U 0.4686274 0.6162291 13773 129 184521 184522 1 -3 Same - - 15.650017 0 21.012873 20.87707162 1.425384 3.246338 1.1056420 2848 Uncharacterized conserved protein S conserved hypothetical protein 1.475027 3.176755 1.0625881 3830 ACT domain-containing protein T conserved hypothetical protein 2.403925e-01 10 2.464403e-03 -6.146907e-04 1.325114e-02 -5.351603e-02 2.360036e-01 17 10 TRUE FALSE 108 TRUE 2.5534540 1.9236061 0.5480306 2.5676904 0.7739415 1.1774989 0.5057097 0.5682360 U 0.4686274 0.8846376 13773 129 184522 184523 1 117 Divergent - + 0.000000 0 0.000000 0.00000000 1.475027 3.176755 1.0625881 3830 ACT domain-containing protein T conserved hypothetical protein 1.342068 2.927488 1.0220040 372 Citrate synthase C citrate synthase part 1, authentic frameshift 1.976326e-03 1 1.767811e-02 -2.583779e-03 1.946115e-02 -2.602825e-01 1.295369e+00 0 10 1 TRUE FALSE 107 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4947521 0.4500198 0.4241419 N 0.5492530 0.6245624 13773 129 184523 184524 1 4 Same + + 0.000000 0 0.000000 0.00000000 1.342068 2.927488 1.0220040 372 Citrate synthase C citrate synthase part 1, authentic frameshift 1.503617 3.355323 1.0537090 372 Citrate synthase C citrate synthase part 2, authentic frameshift 0.000000e+00 0 2.609824e-02 -5.709432e-03 -6.944458e-02 -4.342243e-01 1.822396e+00 C 1 0 FALSE FALSE 108 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4139339 0.4104279 Y 1.4497162 0.7118045 13773 129 184524 184525 1 39 Same + + 0.000000 0 0.000000 0.00000000 1.503617 3.355323 1.0537090 372 Citrate synthase C citrate synthase part 2, authentic frameshift 1.376409 3.021553 1.0662256 2086 Electron transfer flavoprotein, beta subunit C electron transfer flavoprotein beta subunit (etfB) 0.000000e+00 0 1.618204e-02 -3.916006e-03 -1.769678e-02 -3.270886e-01 1.316417e+00 C 0 29 FALSE FALSE 109 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4341659 0.4235217 Y 1.4497162 0.7118045 13773 129 184525 184526 1 -3 Same + + 15.774708 0 41.993208 41.53995251 1.376409 3.021553 1.0662256 2086 Electron transfer flavoprotein, beta subunit C electron transfer flavoprotein beta subunit (etfB) 1.428817 3.143251 1.1100092 2025 Electron transfer flavoprotein, alpha subunit C electron transfer flavoprotein alpha subunit (etfA) 1.274150e-01 9 2.746640e-03 1.692843e-03 2.754643e-02 8.070401e-02 2.382459e-01 C 29 9 FALSE FALSE 110 TRUE 2.5365491 2.0259856 0.5480306 2.2310927 0.7702221 1.0640698 0.5177494 0.5674779 Y 1.4497162 0.9308764 13773 129 184526 184527 1 -35 Convergent + - 0.000000 0 0.000000 -0.05918887 1.428817 3.143251 1.1100092 2025 Electron transfer flavoprotein, alpha subunit C electron transfer flavoprotein alpha subunit (etfA) 1.468869 3.320599 1.1074680 517 FOG: CBS domain R conserved protein with 2 CBS domains 2.915931e-02 1 1.604174e-03 -3.945416e-04 1.560589e-02 -3.364336e-02 1.508038e-01 9 1 FALSE FALSE 111 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6329203 0.7296993 0.5109506 0.5929737 U 0.4686274 0.5589164 13773 129 184527 184528 1 467 Divergent - + 0.000000 0 0.000000 0.00000000 1.468869 3.320599 1.1074680 517 FOG: CBS domain R conserved protein with 2 CBS domains 1.415150 3.004746 1.0387009 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase, degenerate 0.000000e+00 0 2.885685e-03 -6.333788e-04 1.589211e-02 -6.708882e-02 2.683606e-01 1 0 TRUE FALSE 110 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5017564 0.5545399 U 0.4686274 0.6162291 13773 129 184528 184529 1 560 Convergent + - 0.000000 0 0.000000 0.00000000 1.415150 3.004746 1.0387009 365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases I acetyl-coenzyme A synthetase, degenerate 1.338202 2.953281 1.0275008 638 20S proteasome, alpha and beta subunits O proteasome, beta subunit 0.000000e+00 0 5.921128e-03 4.102320e-03 9.790434e-02 2.194363e-01 3.402032e-01 0 0 6 FALSE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5567743 0.5276748 N 0.5492530 0.6245624 13773 129 184529 184530 1 65 Divergent - + 2.079442 0 2.079442 1.64793625 1.338202 2.953281 1.0275008 638 20S proteasome, alpha and beta subunits O proteasome, beta subunit 1.486852 3.271848 1.1315749 430 RNA 3'-terminal phosphate cyclase A RNA 3'-terminal phosphate cyclase 7.884570e-02 6 2.209682e-02 -4.013621e-03 -5.553455e-02 -3.579596e-01 1.607427e+00 0 6 16 TRUE FALSE 110 FALSE 2.9335626 1.6455924 0.5480306 2.9479804 0.7537284 0.9502693 0.4268096 0.4145245 N 0.5492530 0.8417274 13773 129 184530 184531 1 -12 Convergent + - 0.000000 0 0.000000 -0.07232066 1.486852 3.271848 1.1315749 430 RNA 3'-terminal phosphate cyclase A RNA 3'-terminal phosphate cyclase 1.439181 3.444269 1.1442782 109 Polyprenyltransferase (cytochrome oxidase assembly factor) O cytochrome C oxidase assembly factor 2.103529e-02 1 2.272444e-03 -4.330012e-04 1.286062e-02 -7.165706e-03 1.947363e-01 0 16 1 FALSE FALSE 111 FALSE 0.4469764 0.3007156 0.5480306 0.4469764 0.6329203 0.6838321 0.5193588 0.5814495 N 0.5492530 0.5660839 13773 129 184531 184532 1 13 Same - - 0.000000 0 0.000000 0.00000000 1.439181 3.444269 1.1442782 109 Polyprenyltransferase (cytochrome oxidase assembly factor) O cytochrome C oxidase assembly factor 1.427156 3.150273 1.0363125 - - - nitrite reductase (cytochrome C), conjectural 0.000000e+00 0 1.446105e-04 2.959655e-04 2.531128e-02 2.513828e-03 1.742481e-02 1 0 TRUE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5197819 0.6390912 U 0.4686274 0.6162291 13773 129 184532 184533 1 86 Divergent - + 0.000000 0 0.000000 0.00000000 1.427156 3.150273 1.0363125 - - - nitrite reductase (cytochrome C), conjectural 1.381017 2.949200 1.0308698 - - - nitrite reductase (cytochrome d1), conjectural 0.000000e+00 0 2.128803e-03 1.705684e-03 5.176681e-02 8.581295e-02 1.827349e-01 0 0 TRUE FALSE 109 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176850 0.5844907 U 0.4686274 0.6162291 13773 129 184533 184534 1 -27 Same + + 0.000000 0 0.000000 0.00000000 1.381017 2.949200 1.0308698 - - - nitrite reductase (cytochrome d1), conjectural 1.407533 3.008375 0.9993664 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 0.000000e+00 0 7.030976e-04 3.086666e-03 4.913550e-02 1.919733e-01 5.918746e-02 0 0 FALSE FALSE 110 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5467859 0.6207976 U 0.4686274 0.6162291 13773 129 184534 184535 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.407533 3.008375 0.9993664 7 Uroporphyrinogen-III methylase H uroporphyrin-III C-methyltransferase 1.382227 3.384744 1.1815464 - - - conserved hypothetical protein 0.000000e+00 0 6.404222e-04 3.033621e-03 6.347140e-02 1.894171e-01 5.551213e-02 0 2 FALSE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5460088 0.6218902 U 0.4686274 0.6162291 13773 129 184535 184536 1 348 Divergent - + 0.000000 0 0.000000 -0.05918887 1.382227 3.384744 1.1815464 - - - conserved hypothetical protein 1.351086 3.161901 1.1326976 3256 Nitric oxide reductase large subunit P nitric oxide reductase, cytochrome b subunit 2.742453e-02 2 9.697233e-04 6.937849e-03 1.152591e-01 4.377542e-01 4.043093e-02 2 3 TRUE FALSE 110 FALSE 0.4469764 0.3056289 0.5480306 0.4469764 0.6838149 0.7234251 0.6504905 0.6278164 U 0.4686274 0.5589164 13773 129 184536 184537 1 78 Same + + 0.000000 0 0.000000 0.00000000 1.351086 3.161901 1.1326976 3256 Nitric oxide reductase large subunit P nitric oxide reductase, cytochrome b subunit 1.419508 3.261342 1.0582067 - - - conserved within P. aerophilum 0.000000e+00 0 4.681527e-03 3.198283e-03 3.516361e-02 1.725023e-01 2.977490e-01 3 0 FALSE FALSE 111 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5387533 0.5430248 U 0.4686274 0.6162291 13773 129 184537 184538 1 -8 Convergent + - 0.000000 0 0.000000 0.00000000 1.419508 3.261342 1.0582067 - - - conserved within P. aerophilum 1.517095 3.475052 1.1045076 - - - conserved within P. aerophilum 0.000000e+00 0 9.523293e-03 -2.094921e-03 4.624022e-03 -1.353533e-01 6.857314e-01 0 0 FALSE FALSE 112 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4806413 0.4659563 U 0.4686274 0.6162291 13773 129 184538 184539 1 228 Divergent - + 0.000000 0 0.000000 0.00000000 1.517095 3.475052 1.1045076 - - - conserved within P. aerophilum 1.429158 3.599879 1.1942794 - - - hypothetical protein 0.000000e+00 0 7.732866e-03 -1.460851e-03 -6.050079e-03 -7.602033e-02 5.326871e-01 0 0 TRUE FALSE 111 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4993068 0.4869405 U 0.4686274 0.6162291 13773 129 184539 184540 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.429158 3.599879 1.1942794 - - - hypothetical protein 1.368575 3.271456 1.1471130 - - - hypothetical protein 0.000000e+00 0 3.670358e-03 1.841405e-03 5.843044e-02 8.452070e-02 2.977490e-01 0 0 FALSE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5176827 0.5430248 U 0.4686274 0.6162291 13773 129 184540 184541 1 -13 Convergent + - 0.000000 0 0.000000 0.00000000 1.368575 3.271456 1.1471130 - - - hypothetical protein 1.341439 3.132363 1.0396010 - - - hypothetical protein 0.000000e+00 0 7.363754e-04 9.106164e-03 1.404940e-01 5.545382e-01 2.379596e-02 0 0 FALSE FALSE 113 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7008242 0.6358881 U 0.4686274 0.6162291 13773 129 184541 184542 1 47 Same - - 0.000000 0 0.000000 0.00000000 1.341439 3.132363 1.0396010 - - - hypothetical protein 1.363857 2.918746 1.0022815 2180 Nitrate reductase delta subunit C nitrate reductase delta subunit (narJ) 0.000000e+00 0 5.025842e-04 9.624911e-03 1.220314e-01 5.798886e-01 1.526732e-02 0 5 TRUE FALSE 112 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7127765 0.6402042 U 0.4686274 0.6162291 13773 129 184542 184543 1 94 Divergent - + 7.557647 0 9.429449 9.42944913 1.363857 2.918746 1.0022815 2180 Nitrate reductase delta subunit C nitrate reductase delta subunit (narJ) 1.367286 2.963719 1.0666261 5013 Nitrate reductase alpha subunit C nitrate reductase alpha subunit (narG) 6.125049e-02 5 1.175426e-05 7.362389e-03 1.053264e-01 4.785697e-01 4.293769e-04 C 5 15 TRUE FALSE 111 FALSE 2.7298057 1.8312372 0.5480306 2.7751372 0.7448207 0.8869692 0.6662116 0.6535639 Y 1.4497162 0.9111808 13773 129 184543 184544 1 -3 Same + + 20.570195 0 38.476908 37.38124228 1.367286 2.963719 1.0666261 5013 Nitrate reductase alpha subunit C nitrate reductase alpha subunit (narG) 1.302444 2.756448 0.9728836 1140 Nitrate reductase beta subunit C nitrate reductase beta subunit (narH) 5.041264e-01 15 4.204415e-03 1.252767e-02 2.055910e-01 6.422772e-01 6.808775e-02 C 15 15 FALSE FALSE 112 TRUE 2.3521781 2.0064833 0.5480306 2.3003231 0.7783720 1.2594416 0.7344407 0.6184259 Y 1.4497162 0.9307483 13773 129 184544 184545 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.302444 2.756448 0.9728836 1140 Nitrate reductase beta subunit C nitrate reductase beta subunit (narH) 1.380541 3.222411 1.1087109 - - - nitrate reductase subunit, conjectural 0.000000e+00 0 6.099080e-03 1.055333e-02 1.005378e-01 5.460803e-01 1.317751e-01 15 0 FALSE FALSE 113 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6965473 0.5979687 U 0.4686274 0.6162291 13773 129 184545 184546 1 1 Same + + 0.000000 0 0.000000 0.00000000 1.380541 3.222411 1.1087109 - - - nitrate reductase subunit, conjectural 1.393842 3.552060 1.1892221 - - - hypothetical protein 0.000000e+00 0 1.769233e-04 4.077601e-03 6.407687e-02 2.717061e-01 1.221339e-02 0 0 FALSE FALSE 114 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5806704 0.6419378 U 0.4686274 0.6162291 13773 129 184546 184547 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.393842 3.552060 1.1892221 - - - hypothetical protein 1.527761 3.231628 1.0895260 - - - hypothetical protein 0.000000e+00 0 1.793426e-02 -4.395045e-03 -2.425092e-02 -3.120121e-01 1.286649e+00 0 0 FALSE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4366595 0.4247709 U 0.4686274 0.6162291 13773 129 184547 184548 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.527761 3.231628 1.0895260 - - - hypothetical protein 1.382575 3.475554 1.1802312 - - - conserved hypothetical protein 0.000000e+00 0 2.107885e-02 -5.255459e-03 -4.349446e-02 -3.758444e-01 1.513485e+00 0 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4237249 0.4167886 U 0.4686274 0.6162291 13773 129 184548 184549 1 41 Convergent + - 0.000000 0 0.000000 0.00000000 1.382575 3.475554 1.1802312 - - - conserved hypothetical protein 1.342001 3.500039 1.1140560 - - - hypothetical protein 0.000000e+00 0 1.646260e-03 7.528068e-03 1.271204e-01 4.642784e-01 6.609990e-02 0 0 FALSE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6617641 0.6187763 U 0.4686274 0.6162291 13773 129 184549 184550 1 -15 Same - - 0.000000 0 0.000000 0.00000000 1.342001 3.500039 1.1140560 - - - hypothetical protein 1.351213 3.029104 1.0298120 1131 ABC-type multidrug transport system, ATPase component V nitrate ABC transport, ATP-binding protein, putative 0.000000e+00 0 8.485724e-05 1.095885e-02 1.439690e-01 6.320746e-01 2.804202e-03 0 0 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7301852 0.6488220 U 0.4686274 0.6162291 13773 129 184550 184551 1 77 Divergent - + 0.000000 0 0.000000 0.00000000 1.351213 3.029104 1.0298120 1131 ABC-type multidrug transport system, ATPase component V nitrate ABC transport, ATP-binding protein, putative 1.408065 3.502279 1.1814281 755 ABC-type transport system involved in cytochrome c biogenesis, permease component O transport protein, putative 0.000000e+00 0 3.232100e-03 4.340627e-03 5.077051e-02 2.531840e-01 1.933839e-01 0 0 1 TRUE FALSE 115 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5705576 0.5820196 N 0.5492530 0.6245624 13773 129 184551 184552 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.408065 3.502279 1.1814281 755 ABC-type transport system involved in cytochrome c biogenesis, permease component O transport protein, putative 1.391696 3.173105 1.0927777 - - - hypothetical protein 0.000000e+00 0 2.679243e-04 2.586559e-03 5.526297e-02 1.604509e-01 2.499457e-02 1 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5349843 0.6354254 U 0.4686274 0.6162291 13773 129 184552 184553 1 -28 Same + + 0.000000 0 0.000000 0.00000000 1.391696 3.173105 1.0927777 - - - hypothetical protein 1.406147 3.360510 1.1646216 1138 Cytochrome c biogenesis factor O cytochrome C-type biogenesis protein, probable 0.000000e+00 0 2.088302e-04 2.701024e-03 4.846760e-02 1.705492e-01 1.887197e-02 0 0 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5384693 0.6382319 U 0.4686274 0.6162291 13773 129 184553 184554 1 -10 Same + + 0.000000 0 0.000000 0.00000000 1.406147 3.360510 1.1646216 1138 Cytochrome c biogenesis factor O cytochrome C-type biogenesis protein, probable 1.435766 3.479461 1.1602454 - - - hypothetical protein 0.000000e+00 0 8.772953e-04 7.070370e-04 2.442586e-02 1.906928e-02 8.730370e-02 0 0 FALSE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177236 0.6120657 U 0.4686274 0.6162291 13773 129 184554 184555 1 8 Convergent + - 0.000000 0 0.000000 0.00000000 1.435766 3.479461 1.1602454 - - - hypothetical protein 1.406798 3.108210 1.0845349 1084 Predicted GTPase R conserved hypothetical protein 0.000000e+00 0 8.391660e-04 6.968671e-04 3.331588e-02 1.860928e-02 8.238618e-02 0 11 FALSE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177547 0.6134641 U 0.4686274 0.6162291 13773 129 184555 184556 1 44 Divergent - + 0.000000 0 0.000000 -0.73334268 1.406798 3.108210 1.0845349 1084 Predicted GTPase R conserved hypothetical protein 1.402749 3.057254 1.0350883 1912 Uncharacterized conserved protein S conserved hypothetical protein 9.830162e-02 11 1.639140e-05 2.169258e-03 4.705990e-02 1.339344e-01 2.565660e-03 11 23 TRUE FALSE 118 FALSE 0.4469764 0.2222217 0.5480306 0.4469764 0.7764261 1.0073433 0.5256716 0.6491703 U 0.4686274 0.5325774 13773 129 184556 184557 1 242 Same + + 0.000000 0 0.000000 0.00000000 1.402749 3.057254 1.0350883 1912 Uncharacterized conserved protein S conserved hypothetical protein 1.397873 3.039383 1.1213859 - - - conserved within P. aerophilum 0.000000e+00 0 2.378006e-05 2.603408e-03 5.244264e-02 1.727603e-01 2.337719e-03 23 0 FALSE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5390382 0.6495982 U 0.4686274 0.6162291 13773 129 184557 184558 1 395 Convergent + - 0.000000 0 0.000000 0.00000000 1.397873 3.039383 1.1213859 - - - conserved within P. aerophilum 1.460351 3.328908 1.1359643 - - - hypothetical protein 0.000000e+00 0 3.903554e-03 -4.794522e-04 8.061439e-03 -8.113987e-02 3.902653e-01 0 0 FALSE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4975824 0.5139757 U 0.4686274 0.6162291 13773 129 184558 184559 1 56 Divergent - + 0.000000 0 0.000000 0.00000000 1.460351 3.328908 1.1359643 - - - hypothetical protein 1.431160 3.103774 1.0786838 451 Nucleoside-diphosphate-sugar epimerases MG NAD dependent epimerase/dehydratase, putative 0.000000e+00 0 8.521509e-04 -1.812569e-04 1.945422e-02 -1.851798e-02 8.106978e-02 0 4 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5159078 0.6140495 U 0.4686274 0.6162291 13773 129 184559 184560 1 2 Convergent + - 0.000000 0 0.000000 0.00000000 1.431160 3.103774 1.0786838 451 Nucleoside-diphosphate-sugar epimerases MG NAD dependent epimerase/dehydratase, putative 1.590364 3.378452 1.0663066 - - - hypothetical protein 0.000000e+00 0 2.534605e-02 -2.811840e-03 3.586673e-02 -8.541420e-02 9.027187e-01 4 0 FALSE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4965355 0.4462560 U 0.4686274 0.6162291 13773 129 184560 184561 1 826 Divergent - + 0.000000 0 0.000000 0.00000000 1.590364 3.378452 1.0663066 - - - hypothetical protein 1.524147 3.341751 1.0449936 - - - conserved within P. aerophilum 0.000000e+00 0 4.384723e-03 1.011070e-02 1.033513e-01 5.450860e-01 4.325634e-02 0 0 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6953909 0.6266433 U 0.4686274 0.6162291 13773 129 184561 184562 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.524147 3.341751 1.0449936 - - - conserved within P. aerophilum 1.302660 2.845572 0.9458087 - - - conserved hypothetical protein 0.000000e+00 0 4.905642e-02 -1.082090e-02 -6.304760e-02 -6.036816e-01 2.504312e+00 0 1 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.3935827 0.4032760 U 0.4686274 0.6162291 13773 129 184562 184563 1 168 Convergent + - 0.000000 0 0.000000 0.00000000 1.302660 2.845572 0.9458087 - - - conserved hypothetical protein 1.439101 3.404296 1.1459721 428 Predicted divalent heavy-metal cations transporter P conserved protein (gufA) 3.084637e-03 1 1.861629e-02 1.828136e-03 -1.368127e-02 2.021900e-02 8.453271e-01 1 15 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.5159347 0.5176507 0.4510979 U 0.4686274 0.6162291 13773 129 184563 184564 1 56 Divergent - + 0.000000 0 0.000000 0.00000000 1.439101 3.404296 1.1459721 428 Predicted divalent heavy-metal cations transporter P conserved protein (gufA) 1.338231 2.895938 1.0251045 4260 Putative virion core protein (lumpy skin disease virus) S conserved hypothetical protein 0.000000e+00 0 1.017475e-02 1.390912e-03 6.913663e-02 1.810804e-02 6.743397e-01 15 0 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5178031 0.4676734 U 0.4686274 0.6162291 13773 129 184564 184565 1 -3 Same + + 0.000000 0 0.000000 0.00000000 1.338231 2.895938 1.0251045 4260 Putative virion core protein (lumpy skin disease virus) S conserved hypothetical protein 1.477287 3.566472 1.1692515 - - - hypothetical protein 0.000000e+00 0 1.933652e-02 -2.930250e-03 -4.434049e-02 -2.845550e-01 1.393233e+00 0 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4441865 0.4200228 U 0.4686274 0.6162291 13773 129 184565 184566 1 30 Same + + 0.000000 0 0.000000 0.00000000 1.477287 3.566472 1.1692515 - - - hypothetical protein 1.432525 3.229886 1.1116915 4034 Uncharacterized protein conserved in archaea S conserved hypothetical protein 0.000000e+00 0 2.003671e-03 -4.885750e-04 1.422640e-02 -2.772986e-02 1.762324e-01 0 3 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5127991 0.5859323 U 0.4686274 0.6162291 13773 129 184566 184567 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.432525 3.229886 1.1116915 4034 Uncharacterized protein conserved in archaea S conserved hypothetical protein 1.425448 3.282526 1.1133052 - - - conserved within P. aerophilum 0.000000e+00 0 5.008400e-05 4.895283e-04 2.726677e-02 1.380191e-02 7.388346e-03 3 0 FALSE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5182969 0.6442479 U 0.4686274 0.6162291 13773 129 184567 184568 1 30 Same - - 0.000000 0 0.000000 0.00000000 1.425448 3.282526 1.1133052 - - - conserved within P. aerophilum 1.411126 3.166432 1.0615318 - - - hypothetical protein 0.000000e+00 0 2.051289e-04 1.044733e-03 3.536125e-02 5.095096e-02 1.824469e-02 0 0 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5187859 0.6385209 U 0.4686274 0.6162291 13773 129 184568 184569 1 -3 Same - - 0.000000 0 0.000000 0.00000000 1.411126 3.166432 1.0615318 - - - hypothetical protein 1.346232 3.072643 1.0936055 - - - hypothetical protein 0.000000e+00 0 4.211197e-03 4.234548e-03 9.421554e-02 2.435875e-01 2.503839e-01 0 0 TRUE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5668294 0.5623731 U 0.4686274 0.6162291 13773 129 184569 184570 1 152 Divergent - + 0.000000 0 0.000000 0.00000000 1.346232 3.072643 1.0936055 - - - hypothetical protein 1.357142 2.963165 1.0195334 436 Aspartate/tyrosine/aromatic aminotransferase E aminotransferase, putative 0.000000e+00 0 1.190209e-04 9.911567e-03 1.311017e-01 5.932434e-01 4.255485e-03 0 1 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.7176720 0.6470653 U 0.4686274 0.6162291 13773 129 184570 184571 1 -46 Convergent + - 0.000000 0 0.000000 0.00000000 1.357142 2.963165 1.0195334 436 Aspartate/tyrosine/aromatic aminotransferase E aminotransferase, putative 1.400190 3.066281 1.0481942 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved hypothetical protein 1.352502e-03 1 1.853156e-03 4.825956e-03 6.126282e-02 3.105037e-01 1.009513e-01 0 1 7 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4789292 0.5964094 0.6063831 N 0.5492530 0.6245624 13773 129 184571 184572 1 47 Divergent - + 0.000000 0 0.000000 -0.43619026 1.400190 3.066281 1.0481942 37 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control D conserved hypothetical protein 1.321950 2.965937 1.0230379 1859 RNA:NAD 2'-phosphotransferase J conserved hypothetical protein 4.296112e-02 7 6.121415e-03 6.627851e-03 1.341248e-01 3.747347e-01 2.213258e-01 0 7 13 TRUE FALSE 120 FALSE 0.4469764 0.2379634 0.5480306 0.4469764 0.7596462 0.8195450 0.6229790 0.5739549 N 0.5492530 0.5463508 13773 129 184572 184573 1 271 Same + + 0.000000 0 0.000000 0.00000000 1.321950 2.965937 1.0230379 1859 RNA:NAD 2'-phosphotransferase J conserved hypothetical protein 1.415921 3.381080 1.1490684 2512 Uncharacterized membrane-associated protein/domain S conserved protein 0.000000e+00 0 8.830438e-03 4.591598e-03 3.506893e-02 2.270291e-01 4.047811e-01 13 0 FALSE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5604170 0.5116279 U 0.4686274 0.6162291 13773 129 184573 184574 1 509 Same + + 0.000000 0 0.000000 0.00000000 1.415921 3.381080 1.1490684 2512 Uncharacterized membrane-associated protein/domain S conserved protein 1.466509 3.261957 1.0882277 - - - paREP8 0.000000e+00 0 2.559142e-03 -5.361913e-04 1.185325e-02 -5.964157e-02 2.389957e-01 0 0 FALSE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5038693 0.5668045 U 0.4686274 0.6162291 13773 129 184574 184575 1 376 Convergent + - 0.000000 0 0.000000 0.00000000 1.466509 3.261957 1.0882277 - - - paREP8 1.370817 2.914182 1.0373655 620 Methionine synthase II (cobalamin-independent) E 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 0.000000e+00 0 9.156949e-03 -1.217977e-03 2.240429e-02 -1.537747e-01 7.939179e-01 0 15 FALSE FALSE 123 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4757557 0.4559908 U 0.4686274 0.6162291 13773 129 184575 184576 1 58 Divergent - + 0.000000 0 0.000000 -0.35640459 1.370817 2.914182 1.0373655 620 Methionine synthase II (cobalamin-independent) E 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1.386139 3.002407 1.0392579 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase -3.231128e-02 15 2.347793e-04 5.257878e-03 7.653980e-02 3.539338e-01 1.396859e-02 0 15 21 TRUE FALSE 122 FALSE 0.4469764 0.2470818 0.5480306 0.4469764 0.7783720 0.5246599 0.6142207 0.6410384 N 0.5492530 0.5492288 13773 129 184576 184577 1 36 Same + + 0.000000 0 0.000000 0.00000000 1.386139 3.002407 1.0392579 183 Acetyl-CoA acetyltransferase I acetyl-CoA C-acyltransferase 1.366183 3.068641 1.0971303 1840 ABC-type Fe3+ transport system, periplasmic component P conserved protein 0.000000e+00 0 3.982391e-04 5.560225e-03 9.337461e-02 3.704728e-01 2.216739e-02 0 21 0 FALSE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6201159 0.6366745 N 0.5492530 0.6245624 13773 129 184577 184578 1 -3 Convergent + - 0.000000 0 0.000000 0.00000000 1.366183 3.068641 1.0971303 1840 ABC-type Fe3+ transport system, periplasmic component P conserved protein 1.477375 3.233519 1.1193939 - - - paREP8 0.000000e+00 0 1.236362e-02 -2.213939e-03 -2.187245e-02 -2.343161e-01 1.057598e+00 0 0 FALSE FALSE 124 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4558376 0.4354257 U 0.4686274 0.6162291 13773 129 184578 184579 1 44 Same - - 0.000000 0 0.000000 0.00000000 1.477375 3.233519 1.1193939 - - - paREP8 1.500733 3.370857 1.0556176 3432 Predicted transcriptional regulator K conserved hypothetical protein 0.000000e+00 0 5.455865e-04 1.281969e-03 4.019476e-02 1.741680e-01 2.902800e-02 0 2 TRUE FALSE 123 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5398979 0.6335997 U 0.4686274 0.6162291 13773 129 184579 184580 1 -22 Same - - 0.000000 0 0.000000 0.00000000 1.500733 3.370857 1.0556176 3432 Predicted transcriptional regulator K conserved hypothetical protein 1.352233 3.417203 1.1547983 - - - hypothetical protein 0.000000e+00 0 2.205214e-02 -4.892540e-03 -1.767955e-02 -3.914857e-01 1.630864e+00 2 0 TRUE FALSE 122 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4212174 0.4139045 U 0.4686274 0.6162291 13773 129 184580 184581 1 1 Same - - 0.000000 0 0.000000 0.00000000 1.352233 3.417203 1.1547983 - - - hypothetical protein 1.392454 3.337052 1.1768822 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 0.000000e+00 0 1.617703e-03 5.844348e-03 7.292316e-02 3.679731e-01 8.150740e-02 0 10 TRUE FALSE 121 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6186980 0.6138313 U 0.4686274 0.6162291 13773 129 184581 184582 1 82 Divergent - + 0.000000 0 0.000000 0.00000000 1.392454 3.337052 1.1768822 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 1.400797 3.308903 1.1551574 - - - conserved hypothetical protein 0.000000e+00 0 6.961064e-05 2.982044e-03 5.328378e-02 1.972601e-01 4.877463e-03 10 0 TRUE FALSE 120 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5490032 0.6464448 U 0.4686274 0.6162291 13773 129 184582 184583 1 -28 Convergent + - 0.000000 0 0.000000 0.00000000 1.400797 3.308903 1.1551574 - - - conserved hypothetical protein 1.351875 2.877678 1.0198789 - - - conserved within P. aerophilum 0.000000e+00 0 2.393412e-03 5.035171e-03 9.826031e-02 3.147969e-01 1.268081e-01 0 0 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5974325 0.5988589 U 0.4686274 0.6162291 13773 129 184583 184584 1 140 Same - - 0.000000 0 0.000000 0.00000000 1.351875 2.877678 1.0198789 - - - conserved within P. aerophilum 1.457726 3.629367 1.1969932 - - - hypothetical protein 0.000000e+00 0 1.120449e-02 -6.302682e-04 -1.168063e-02 -1.165043e-01 8.439165e-01 0 0 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4861632 0.4512878 U 0.4686274 0.6162291 13773 129 184584 184585 1 394 Divergent - + 0.000000 0 0.000000 0.00000000 1.457726 3.629367 1.1969932 - - - hypothetical protein 1.380575 3.299493 1.1281623 - - - hypothetical protein 0.000000e+00 0 5.952342e-03 -4.485062e-04 2.812797e-02 -8.793215e-02 5.338080e-01 0 0 TRUE FALSE 119 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4960471 0.4864093 U 0.4686274 0.6162291 13773 129 184585 184586 1 -7 Same + + 0.000000 0 0.000000 0.00000000 1.380575 3.299493 1.1281623 - - - hypothetical protein 1.412168 3.003666 1.0370690 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 0.000000e+00 0 9.981239e-04 2.777853e-03 4.438825e-02 1.687587e-01 8.238618e-02 0 1 FALSE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5383276 0.6134641 U 0.4686274 0.6162291 13773 129 184586 184587 1 692 Convergent + - 0.000000 0 0.000000 0.00000000 1.412168 3.003666 1.0370690 1180 Pyruvate-formate lyase-activating enzyme O pyruvate formate-lyase activating enzyme homolog 1.506469 3.459895 1.1282344 - - - paREP1 1.851224e-04 1 8.892751e-03 -2.160373e-03 -7.259780e-04 -1.589107e-01 6.997843e-01 1 1 FALSE FALSE 121 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4421536 0.4744672 0.4649206 U 0.4686274 0.6162291 13773 129 184587 184588 1 152 Same - - 0.000000 0 0.000000 0.00000000 1.506469 3.459895 1.1282344 - - - paREP1 1.471631 3.077425 1.1065093 - - - carbonic anhydrase part 2, authentic frameshift 0.000000e+00 0 1.213684e-03 1.114650e-03 2.710731e-02 1.534743e-01 6.929460e-02 1 0 TRUE FALSE 120 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5317337 0.6180080 U 0.4686274 0.6162291 13773 129 184588 184589 1 34 Same - - 0.000000 0 0.000000 0.00000000 1.471631 3.077425 1.1065093 - - - carbonic anhydrase part 2, authentic frameshift 1.438484 3.327847 1.1152304 288 Carbonic anhydrase P carbonic anhydrase part 1, authentic frameshift 0.000000e+00 0 1.098763e-03 -2.612621e-04 1.706599e-02 -8.646438e-03 9.756633e-02 0 0 TRUE FALSE 119 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5190341 0.6075710 U 0.4686274 0.6162291 13773 129 184589 184590 1 363 Same - - 0.000000 0 0.000000 0.00000000 1.438484 3.327847 1.1152304 288 Carbonic anhydrase P carbonic anhydrase part 1, authentic frameshift 1.386091 3.116216 1.1105273 616 Periplasmic serine proteases (ClpP class) OU protease IV, conjectural 0.000000e+00 0 2.744992e-03 8.430024e-04 4.100045e-02 1.658608e-02 2.596853e-01 0 0 TRUE FALSE 118 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5180359 0.5580942 U 0.4686274 0.6162291 13773 129 184590 184591 1 29 Same - - 0.000000 0 0.000000 0.00000000 1.386091 3.116216 1.1105273 616 Periplasmic serine proteases (ClpP class) OU protease IV, conjectural 1.459403 3.174885 1.1130459 2248 Predicted hydrolase (metallo-beta-lactamase superfamily) R conserved hypothetical protein 0.000000e+00 0 5.374663e-03 -5.230769e-04 3.955320e-03 -9.495532e-02 5.127131e-01 0 8 TRUE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4936931 0.4912800 U 0.4686274 0.6162291 13773 129 184591 184592 1 2 Same - - 0.000000 0 0.000000 0.00000000 1.459403 3.174885 1.1130459 2248 Predicted hydrolase (metallo-beta-lactamase superfamily) R conserved hypothetical protein 1.366860 3.290741 1.1518905 - - - hypothetical protein 0.000000e+00 0 8.564216e-03 -6.771193e-04 3.080454e-02 -1.205825e-01 7.427979e-01 8 0 TRUE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4848630 0.4602020 U 0.4686274 0.6162291 13773 129 184592 184593 1 59 Same - - 0.000000 0 0.000000 0.00000000 1.366860 3.290741 1.1518905 - - - hypothetical protein 1.368479 3.332175 1.1423208 3366 Uncharacterized protein conserved in archaea S hypothetical protein 0.000000e+00 0 2.619817e-06 7.008991e-03 1.020005e-01 4.617940e-01 1.702194e-04 0 2 TRUE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.6607487 0.6547351 U 0.4686274 0.6162291 13773 129 184593 184594 1 44 Divergent - + 0.000000 0 0.000000 0.00000000 1.368479 3.332175 1.1423208 3366 Uncharacterized protein conserved in archaea S hypothetical protein 1.404465 3.308175 1.1439954 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 3.728161e-04 1 1.295049e-03 3.890967e-03 5.436587e-02 2.484596e-01 9.236375e-02 2 1 TRUE FALSE 114 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.6329203 0.4500832 0.5690874 0.6101085 U 0.4686274 0.6162291 13773 129 184594 184595 1 40 Same + + 0.000000 0 0.000000 0.00000000 1.404465 3.308175 1.1439954 577 ABC-type antimicrobial peptide transport system, permease component V conserved hypothetical protein 1.624174 3.668618 1.1384561 - - - hypothetical protein 0.000000e+00 0 4.827185e-02 -8.108189e-03 -3.845361e-03 -3.334515e-01 1.619124e+00 1 0 FALSE FALSE 115 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4312286 0.4143169 U 0.4686274 0.6162291 13773 129 184595 184596 1 340 Same + + 0.000000 0 0.000000 0.00000000 1.624174 3.668618 1.1384561 - - - hypothetical protein 1.387250 3.161393 1.0880930 1401 GTPase subunit of restriction endonuclease V hypothetical protein 0.000000e+00 0 5.613275e-02 -1.108261e-02 -1.742077e-01 -4.762603e-01 2.046459e+00 0 0 FALSE FALSE 116 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4088691 0.4077159 U 0.4686274 0.6162291 13773 129 184596 184597 1 53 Same + + 0.000000 0 0.000000 0.00000000 1.387250 3.161393 1.0880930 1401 GTPase subunit of restriction endonuclease V hypothetical protein 1.505792 3.341865 1.1461190 - - - hypothetical protein 0.000000e+00 0 1.405212e-02 -3.489297e-03 -2.299327e-02 -2.848660e-01 1.139634e+00 0 0 FALSE FALSE 117 TRUE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.4440093 0.4309702 U 0.4686274 0.6162291 13773 129 184597 184598 1 -78 Convergent + - 0.000000 0 0.000000 0.00000000 1.505792 3.341865 1.1461190 - - - hypothetical protein 1.448396 3.252345 1.0893658 - - - hypothetical protein 0.000000e+00 0 3.294303e-03 -1.630287e-04 1.133924e-02 3.648938e-02 2.234975e-01 0 0 FALSE FALSE 118 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5177617 0.5730737 U 0.4686274 0.6162291 13773 129 184598 181994 1 187 Divergent - + 0.000000 0 0.000000 0.00000000 1.448396 3.252345 1.0893658 - - - hypothetical protein 1.335192 2.921130 1.0080980 2419 Uncharacterized conserved protein S conserved hypothetical protein 0.000000e+00 0 1.281514e-02 3.482425e-04 5.907673e-02 -5.774030e-02 8.509815e-01 0 2 TRUE FALSE 117 FALSE 0.4469764 0.4914888 0.5480306 0.4469764 0.5091911 0.5078922 0.5046173 0.4503392 U 0.4686274 0.6162291