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Our Science – Raffeld Website

Mark Raffeld, M.D.

Selected Publications
1)  Yabe Y, Sebasigari D, Jin L, Rudelius M, Theresa D, Miyake K, Miida T, Pittaluga S, Raffeld M.
The MDM2 Antagonist Nutlin-3 Displays Anti-Proliferative and Pro-Apoptotic Activity in Mantle Cell Lymphoma.
Clinical Cancer Research. 2008. In Press. [Journal]
2)  Feldman AL, Arber DA, Pittaluga S, Martinez A, Burke JS, Raffeld M, Camos M, Warnke R, Jaffe ES.
Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: evidence for transdifferentiation of the follicular lymphoma clone.
Blood. 111: 5433-9, 2008. [Journal]
3)  Qi CF, Li Z, Raffeld M, Wang H, Kovalchuk AL, Morse HC.
Differential expression of IRF8 in subsets of macrophages and dendritic cells and effects of IRF8 deficiency on splenic B cell and macrophage compartments.
Immunol. Res. 2008. [Journal]
4)  Martinez A, Pittaluga S, Rudelius M, Davies-Hill T, Sebasigari D, Fountaine TJ, Hewitt S, Jaffe ES, Raffeld M.
Expression of the interferon regulatory factor 8/ICSBP-1 in human reactive lymphoid tissues and B-cell lymphomas: a novel germinal center marker.
Am. J. Surg. Pathol. 32: 1190-200, 2008. [Journal]
5)  Vistica DT, Krosky PM, Kenney S, Raffeld M, Shoemaker RH.
Immunohistochemical discrimination between the ASPL-TFE3 fusion proteins of alveolar soft part sarcoma.
J. Pediatr. Hematol. Oncol. 30: 46-52, 2008. [Journal]
6)  Wilson WH, Dunleavy K, Pittaluga S, Hegde U, Grant N, Steinberg SM, Raffeld M, Gutierrez M, Chabner BA, Staudt L, Jaffe ES, Janik JE.
Phase II study of dose-adjusted EPOCH and rituximab in untreated diffuse large B-cell lymphoma with analysis of germinal center and post-germinal center biomarkers.
J. Clin. Oncol. 26: 2717-24, 2008. [Journal]
7)  Mehta GU, Shively SB, Duong H, Tran MG, Moncrief TJ, Smith JH, Li J, Edwards NA, Lonser RR, Zhuang Z, Merrill MJ, Raffeld M, Maxwell PH, Oldfield EH, Vortmeyer AO.
Progression of epididymal maldevelopment into hamartoma-like neoplasia in VHL disease.
Neoplasia. 10: 1146-53, 2008. [Journal]
8)  Kim RD, Greenberg DE, Ehrmantraut ME, Ding L, Shea Y, Chernick M, Jolley C, Raffeld M, Avila N, Sachdev V, Barnhart LA, Anderson VL, Claypool R, Fitzgerald A, Darnell D, Decastro R, Porcella SF, Olivier KN, Moss J, Holland SM.
Pulmonary Nontuberculous Mycobacterial Disease: Prospective Study of a Distinct Preexisting Syndrome.
Am. J. Respir. Crit. Care Med. 2008. [Journal]
9)  Klier M, Anastasov N, Hermann A, Meindl T, Angermeier D, Raffeld M, Fend F, Quintanilla-Martinez L.
Specific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2.
Leukemia. 2008. [Journal]
10)  Srivastava M, Torosyan Y, Raffeld M, Eidelman O, Pollard HB, Bubendorf L.
ANXA7 expression represents hormone-relevant tumor suppression in different cancers.
Int. J. Cancer. 121: 2628-36, 2007. [Journal]
11)  Hardy NM, Grady C, Pentz R, Stetler-Stevenson M, Raffeld M, Fontaine LS, Babb R, Bishop MR, Caporaso N, Marti GE.
Bioethical considerations of monoclonal B-cell lymphocytosis: donor transfer after haematopoietic stem cell transplantation.
Br. J. Haematol. 139: 824-31, 2007. [Journal]
12)  Manosca F, Schinstine M, Fetsch PA, Sorbara L, Maria Wilder A, Brosky K, Erickson D, Raffeld M, Filie AC, Abati A.
Diagnostic effects of prolonged storage on fresh effusion samples.
Diagn. Cytopathol. 35: 6-11, 2007. [Journal]
13)  Mao Z, Quintanilla-Martinez L, Raffeld M, Richter M, Krugmann J, Burek C, Hartmann E, Rudiger T, Jaffe ES, Müller-Hermelink HK, Ott G, Fend F, Rosenwald A.
IgVH mutational status and clonality analysis of Richter's transformation: diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution.
Am. J. Surg. Pathol. 31: 1605-14, 2007. [Journal]
14)  Huang AM, Rudelius M, Sharan S, McAllister JM, Raffeld M, Christenson LK, Sterneck E.
The Cebpd (C/EBPdelta) gene is induced by luteinizing hormones in ovarian theca and interstitial cells but is not essential for mouse ovary function.
PLoS ONE. 2: e1334, 2007. [Journal]
15)  Mehta GU, Shively SB, Gläsker S, Bechert CJ, Zhuang Z, Raffeld M, Lonser RR, Oldfield EH, Vortmeyer AO.
von Hippel-Lindau disease: epididymal cystadenoma targeted by metastatic events.
Urology. 69: 1209.e9-12, 2007. [Journal]
16)  Lorenzi PL, Reinhold WC, Rudelius M, Gunsior M, Shankavaram U, Bussey KJ, Scherf U, Eichler GS, Martin SE, Chin K, Gray JW, Kohn EC, Horak ID, Von Hoff DD, Raffeld M, Goldsmith PK, Caplen NJ, Weinstein JN.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Mol. Cancer Ther. 5: 2613-23, 2006. [Journal]
17)  Arons E, Sorbara L, Raffeld M, Stetler-Stevenson M, Steinberg SM, Liewehr DJ, Pastan I, Kreitman RJ.
Characterization of T-cell repertoire in hairy cell leukemia patients before and after recombinant immunotoxin BL22 therapy.
Cancer Immunol. Immunother. 55: 1100-10, 2006. [Journal]
18)  Rudelius M, Pittaluga S, Nishizuka S, Pham TH, Fend F, Jaffe ES, Quintanilla-Martinez L, Raffeld M.
Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma.
Blood. 108: 1668-76, 2006. [Journal]
19)  Vortmeyer AO, Tran MG, Zeng W, Gläsker S, Riley C, Tsokos M, Ikejiri B, Merrill MJ, Raffeld M, Zhuang Z, Lonser RR, Maxwell PH, Oldfield EH.
Evolution of VHL tumourigenesis in nerve root tissue.
J. Pathol. 210: 374-82, 2006. [Journal]
20)  Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W, Frank JA, Reitz M, Finkel T.
Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
J. Exp. Med. 203: 1235-47, 2006. [Journal]
21)  Prakash S, Fountaine T, Raffeld M, Jaffe ES, Pittaluga S.
IgD positive L&H cells identify a unique subset of nodular lymphocyte predominant Hodgkin lymphoma.
Am. J. Surg. Pathol. 30: 585-92, 2006. [Journal]
22)  Arons E, Margulies I, Sorbara L, Raffeld M, Stetler-Stevenson M, Pastan I, Kreitman RJ.
Minimal residual disease in hairy cell leukemia patients assessed by clone-specific polymerase chain reaction.
Clin. Cancer Res. 12: 2804-11, 2006. [Journal]
23)  Kobrin C, Cha SC, Qin H, Raffeld M, Fend F, Quintanilla-Martinez L, Grove S, Jaffe ES, Kwak LW.
Molecular analysis of light-chain switch and acute lymphoblastic leukemia transformation in two follicular lymphomas: implications for lymphomagenesis.
Leuk. Lymphoma. 47: 1523-34, 2006. [Journal]
24)  Quintanilla-Martinez L, Pittaluga S, Miething C, Klier M, Rudelius M, Davies-Hill T, Anastasov N, Martinez A, Vivero A, Duyster J, Jaffe ES, Fend F, Raffeld M.
NPM-ALK-dependent expression of the transcription factor CCAAT/enhancer binding protein beta in ALK-positive anaplastic large cell lymphoma.
Blood. 108: 2029-36, 2006. [Journal]
25)  Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L, Huang AM, Sterneck E.
C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution.
Development. 132: 4675-85, 2005. [Journal]
26)  Feldman AL, Berthold F, Arceci RJ, Abramowsky C, Shehata BM, Mann KP, Lauer SJ, Pritchard J, Raffeld M, Jaffe ES.
Clonal relationship between precursor T-lymphoblastic leukaemia/lymphoma and Langerhans-cell histiocytosis.
Lancet Oncol. 6: 435-7, 2005. [Journal]
27)  Stevens EV, Raffeld M, Espina V, Kristensen GB, Trope' CG, Kohn EC, Davidson B.
Expression of xeroderma pigmentosum A protein predicts improved outcome in metastatic ovarian carcinoma.
Cancer. 103: 2313-9, 2005. [Journal]
28)  Schrager JA, Pittaluga S, Raffeld M, Jaffe ES.
Granulomatous reaction in Burkitt lymphoma: correlation with EBV positivity and clinical outcome.
Am. J. Surg. Pathol. 29: 1115-6, 2005. [Journal]
29)  Maric I, Pittaluga S, Dale JK, Niemela JE, Delsol G, Diment J, Rosai J, Raffeld M, Puck JM, Straus SE, Jaffe ES.
Histologic features of sinus histiocytosis with massive lymphadenopathy in patients with autoimmune lymphoproliferative syndrome.
Am. J. Surg. Pathol. 29: 903-11, 2005. [Journal]
30)  Furukawa M, Raffeld M, Mateo C, Sakamoto A, Moody TW, Ito T, Venzon DJ, Serrano J, Jensen RT.
Increased expression of insulin-like growth factor I and/or its receptor in gastrinomas is associated with low curability, increased growth, and development of metastases.
Clin. Cancer Res. 11: 3233-42, 2005. [Journal]
31)  Traverse-Glehen A, Pittaluga S, Gaulard P, Sorbara L, Alonso MA, Raffeld M, Jaffe ES.
Mediastinal gray zone lymphoma: the missing link between classic Hodgkin's lymphoma and mediastinal large B-cell lymphoma.
Am. J. Surg. Pathol. 29: 1411-21, 2005. [Journal]
32)  Hassan R, Laszik ZG, Lerner M, Raffeld M, Postier R, Brackett D.
Mesothelin is overexpressed in pancreaticobiliary adenocarcinomas but not in normal pancreas and chronic pancreatitis.
Am. J. Clin. Pathol. 124: 838-45, 2005. [Journal]
33)  Gulmann C, Espina V, Petricoin E, Longo DL, Santi M, Knutsen T, Raffeld M, Jaffe ES, Liotta LA, Feldman AL.
Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma.
Clin. Cancer Res. 11: 5847-55, 2005. [Journal]
34)  Zaragoza C, Li RM, Fahle GA, Fischer SH, Raffeld M, Lewis AM, Kopp JB.
Squirrel monkeys support replication of BK virus more efficiently than simian virus 40: an animal model for human BK virus infection.
J. Virol. 79: 1320-6, 2005. [Journal]
35)  Guedez L, Martinez A, Zhao S, Vivero A, Pittaluga S, Stetler-Stevenson M, Raffeld M, Stetler-Stevenson WG.
Tissue inhibitor of metalloproteinase 1 (TIMP-1) promotes plasmablastic differentiation of a Burkitt lymphoma cell line: implications in the pathogenesis of plasmacytic/plasmablastic tumors.
Blood. 105: 1660-8, 2005. [Journal]
36)  Zu Y, Steinberg SM, Campo E, Hans CP, Weisenburger DD, Braziel RM, Delabie J, Gascoyne RD, Muller-Hermlink K, Pittaluga S, Raffeld M, Chan WC, Jaffe ES.
Validation of tissue microarray immunohistochemistry staining and interpretation in diffuse large B-cell lymphoma.
Leuk. Lymphoma. 46: 693-701, 2005. [Journal]
37)  Martinez A, Pittaluga S, Villamor N, Colomer D, Rozman M, Raffeld M, Montserrat E, Campo E, Jaffe ES.
Clonal T-cell populations and increased risk for cytotoxic T-cell lymphomas in B-CLL patients: clinicopathologic observations and molecular analysis.
Am. J. Surg. Pathol. 28: 849-58, 2004. [Journal]
38)  Taylor ML, Sehgal D, Raffeld M, Obiakor H, Akin C, Mage RG, Metcalfe DD.
Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis.
The Journal of molecular diagnostics : JMD. 6: 335-42, 2004. [Journal]
39)  Janik JE, Morris JC, Pittaluga S, McDonald K, Raffeld M, Jaffe ES, Grant N, Gutierrez M, Waldmann TA, Wilson WH.
Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma.
Blood. 104: 3355-7, 2004. [Journal]
40)  Feldman AL, Minniti C, Santi M, Downing JR, Raffeld M, Jaffe ES.
Histiocytic sarcoma after acute lymphoblastic leukaemia: a common clonal origin.
Lancet Oncol. 5: 248-50, 2004. [Journal]
41)  Maric I, Bryant R, Abu-Asab M, Cohen JI, Vivero A, Jaffe ES, Raffeld M, Tsokos M, Banks PM, Pittaluga S.
Human herpesvirus-6-associated acute lymphadenitis in immunocompetent adults.
Mod. Pathol. 17: 1427-33, 2004. [Journal]
42)  Papadopoulos EJ, Jaffe ES, Elgart GW, Raffeld M, Turner ML.
Periodic fever with atypical dyshidrosis--quiz case.
Arch Dermatol. 140: 479-84, 2004. [Journal]
43)  Srivastava M, Bubendorf L, Raffeld M, Bucher C, Torhorst J, Sauter G, Olsen C, Kallioniemi OP, Eidelman O, Pollard HB.
Prognostic impact of ANX7-GTPase in metastatic and HER2-negative breast cancer patients.
Clin. Cancer Res. 10: 2344-50, 2004. [Journal]
44)  Zha H, Raffeld M, Charboneau L, Pittaluga S, Kwak LW, Petricoin E, Liotta LA, Jaffe ES.
Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray.
Lab. Invest. 84: 235-44, 2004. [Journal]
45)  Mattu R, Sorbara L, Filie AC, Little R, Wilson W, Raffeld M, Abati A.
Utilization of polymerase chain reaction on archival cytologic material: a comparison with fresh material with special emphasis on cerebrospinal fluids.
Mod. Pathol. 17: 1295-301, 2004. [Journal]
46)  Barry TS, Jaffe ES, Sorbara L, Raffeld M, Pittaluga S.
Peripheral T-cell lymphomas expressing CD30 and CD15.
Am. J. Surg. Pathol. 27: 1513-22, 2003. [Journal]
47)  Mousses S, Bubendorf L, Wagner U, Hostetter G, Kononen J, Cornelison R, Goldberger N, Elkahloun AG, Willi N, Koivisto P, Ferhle W, Raffeld M, Sauter G, Kallioniemi OP.
Clinical validation of candidate genes associated with prostate cancer progression in the CWR22 model system using tissue microarrays.
Cancer Res. 62: 1256-60, 2002. [Journal]
48)  Fend F, Martinez A, Quintanilla-Martinez L, Sanz L, Combalia N, Raffeld M, Jaffe ES, Montserrat E, Campo E.
Clonally unrelated Hodgkin's disease following autologous stem cell transplant for B-cell lymphoma.
Br. J. Haematol. 116: 329-33, 2002. [Journal]
49)  Wilson WH, Grossbard ML, Pittaluga S, Cole D, Pearson D, Drbohlav N, Steinberg SM, Little RF, Janik J, Gutierrez M, Raffeld M, Staudt L, Cheson BD, Longo DL, Harris N, Jaffe ES, Chabner BA, Wittes R, Balis F.
Dose-adjusted EPOCH chemotherapy for untreated large B-cell lymphomas: a pharmacodynamic approach with high efficacy.
Blood. 99: 2685-93, 2002. [Journal]
50)  Cong P, Raffeld M, Teruya-Feldstein J, Sorbara L, Pittaluga S, Jaffe ES.
In situ localization of follicular lymphoma: description and analysis by laser capture microdissection.
Blood. 99: 3376-82, 2002. [Journal]
51)  Ahram M, Best CJ, Flaig MJ, Gillespie JW, Leiva IM, Chuaqui RF, Zhou G, Shu H, Duray PH, Linehan WM, Raffeld M, Ornstein DK, Zhao Y, Petricoin EF, Emmert-Buck MR.
Proteomic analysis of human prostate cancer.
Mol. Carcinog. 33: 9-15, 2002. [Journal]
52)  Srivastava M, Bubendorf L, Nolan L, Glasman M, Leighton X, Miller G, Fehrle W, Raffeld M, Eidelman O, Kallioniemi OP, Srivastava S, Pollard HB.
ANX7 as a bio-marker in prostate and breast cancer progression.
Dis. Markers. 17: 115-20, 2001. [Journal]
53)  Srivastava M, Bubendorf L, Srikantan V, Fossom L, Nolan L, Glasman M, Leighton X, Fehrle W, Pittaluga S, Raffeld M, Koivisto P, Willi N, Gasser TC, Kononen J, Sauter G, Kallioniemi OP, Srivastava S, Pollard HB.
ANX7, a candidate tumor suppressor gene for prostate cancer.
Proc. Natl. Acad. Sci. U.S.A. 98: 4575-80, 2001. [Journal]
54)  Kuttler F, Amé P, Clark H, Haughey C, Mougin C, Cahn JY, Dang CV, Raffeld M, Fest T.
c-myc box II mutations in Burkitt's lymphoma-derived alleles reduce cell-transformation activity and lower response to broad apoptotic stimuli.
Oncogene. 20: 6084-94, 2001. [Journal]
55)  Njoroge JM, Mitchell LB, Centola M, Kastner D, Raffeld M, Miller JL.
Characterization of viable autofluorescent macrophages among cultured peripheral blood mononuclear cells.
Cytometry. 44: 38-44, 2001. [Journal]
56)  Teruya-Feldstein J, Kingma DW, Weiss A, Sorbara L, Burd PR, Raffeld M, Mueller BU, Tosato G, Jaffe ES.
Chemokine gene expression and clonal analysis of B cells in tissues involved by lymphoid interstitial pneumonitis from HIV-infected pediatric patients.
Mod. Pathol. 14: 929-36, 2001. [Journal]
57)  Beaty MW, Toro J, Sorbara L, Stern JB, Pittaluga S, Raffeld M, Wilson WH, Jaffe ES.
Cutaneous lymphomatoid granulomatosis: correlation of clinical and biologic features.
Am. J. Surg. Pathol. 25: 1111-20, 2001. [Journal]
58)  Hedenfalk I, Duggan D, Chen Y, Radmacher M, Bittner M, Simon R, Meltzer P, Gusterson B, Esteller M, Kallioniemi OP, Wilfond B, Borg A, Trent J, Raffeld M, Yakhini Z, Ben-Dor A, Dougherty E, Kononen J, Bubendorf L, Fehrle W, Pittaluga S, Gruvberger S, Loman N, Johannsson O, Olsson H, Sauter G.
Gene-expression profiles in hereditary breast cancer.
N. Engl. J. Med. 344: 539-48, 2001. [Journal]
59)  Lopatin U, Yao X, Williams RK, Bleesing JJ, Dale JK, Wong D, Teruya-Feldstein J, Fritz S, Morrow MR, Fuss I, Sneller MC, Raffeld M, Fleisher TA, Puck JM, Strober W, Jaffe ES, Straus SE.
Increases in circulating and lymphoid tissue interleukin-10 in autoimmune lymphoproliferative syndrome are associated with disease expression.
Blood. 97: 3161-70, 2001. [Journal]
60)  Dagher R, Pham TA, Sorbara L, Kumar S, Long L, Bernstein D, Mackall C, Raffeld M, Tsokos M, Helman L.
Molecular confirmation of Ewing sarcoma.
J. Pediatr. Hematol. Oncol. 23: 221-4, 2001. [Journal]
61)  Yao X, Teruya-Feldstein J, Raffeld M, Sorbara L, Jaffe ES.
Peripheral T-cell lymphoma with aberrant expression of CD79a and CD20: a diagnostic pitfall.
Mod. Pathol. 14: 105-10, 2001. [Journal]
62)  Yao L, Pike SE, Setsuda J, Parekh J, Gupta G, Raffeld M, Jaffe ES, Tosato G.
Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12.
Blood. 96: 1900-5, 2000. [Journal]
63)  Goebel SU, Peghini PL, Goldsmith PK, Spiegel AM, Gibril F, Raffeld M, Jensen RT, Serrano J.
Expression of the calcium-sensing receptor in gastrinomas.
J. Clin. Endocrinol. Metab. 85: 4131-7, 2000. [Journal]
64)  Fend F, Raffeld M.
Laser capture microdissection in pathology.
J. Clin. Pathol. 53: 666-72, 2000. [Journal]
65)  Lei JY, Wang Y, Jaffe ES, Turner ML, Raffeld M, Sorbara L, Morris J, Holland SM, Duray PH.
Microcystic adnexal carcinoma associated with primary immunodeficiency, recurrent diffuse herpes simplex virus infection, and cutaneous T-cell lymphoma.
The American Journal of dermatopathology. 22: 524-9, 2000. [Journal]
66)  Kumar S, Perlman E, Harris CA, Raffeld M, Tsokos M.
Myogenin is a specific marker for rhabdomyosarcoma: an immunohistochemical study in paraffin-embedded tissues.
Mod. Pathol. 13: 988-93, 2000. [Journal]
67)  Beaty MW, Kumar S, Sorbara L, Miller K, Raffeld M, Jaffe ES.
A biophenotypic human herpesvirus 8--associated primary bowel lymphoma.
Am. J. Surg. Pathol. 23: 992-4, 1999. [Journal]
68)  Thieblemont C, Pack S, Sakai A, Beaty M, Pak E, Vortmeyer AO, Wellmann A, Zhuang Z, Jaffe ES, Raffeld M.
Allelic loss of 11q13 as detected by MEN1-FISH is not associated with mutation of the MEN1 gene in lymphoid neoplasms.
Leukemia. 13: 85-91, 1999. [Journal]
69)  Krenacs L, Krenacs T, Raffeld M.
Antigen retrieval for immunohistochemical reactions in routinely processed paraffin sections.
Methods Mol. Biol. 115: 85-93, 1999. [Journal]
70)  Raffeld M, Jaffe ES.
Avidin-biotin labeling of cellular antigens in cryostat-sectioned tissue.
Methods Mol. Biol. 115: 215-22, 1999. [Journal]
71)  Fend F, Quintanilla-Martinez L, Kumar S, Beaty MW, Blum L, Sorbara L, Jaffe ES, Raffeld M.
Composite low grade B-cell lymphomas with two immunophenotypically distinct cell populations are true biclonal lymphomas. A molecular analysis using laser capture microdissection.
Am. J. Pathol. 154: 1857-66, 1999. [Journal]
72)  Cobo F, Hernández S, Hernández L, Pinyol M, Bosch F, Esteve J, López-Guillermo A, Palacín A, Raffeld M, Montserrat E, Jaffe ES, Campo E.
Expression of potentially oncogenic HHV-8 genes in an EBV-negative primary effusion lymphoma occurring in an HIV-seronegative patient.
J. Pathol. 189: 288-93, 1999. [Journal]
73)  Jaffe ES, Krenacs L, Kumar S, Kingma DW, Raffeld M.
Extranodal peripheral T-cell and NK-cell neoplasms.
Am. J. Clin. Pathol. 111: S46-55, 1999. [Journal]
74)  Quintanilla-Martinez L, Franklin JL, Guerrero I, Krenacs L, Naresh KN, Rama-Rao C, Bhatia K, Raffeld M, Magrath IT.
Histological and immunophenotypic profile of nasal NK/T cell lymphomas from Peru: high prevalence of p53 overexpression.
Hum. Pathol. 30: 849-55, 1999. [Journal]
75)  Fend F, Emmert-Buck MR, Chuaqui R, Cole K, Lee J, Liotta LA, Raffeld M.
Immuno-LCM: laser capture microdissection of immunostained frozen sections for mRNA analysis.
Am. J. Pathol. 154: 61-6, 1999. [Journal]
76)  Kingma DW, Mueller BU, Frekko K, Sorbara LR, Wood LV, Katz D, Raffeld M, Jaffe ES.
Low-grade monoclonal Epstein-Barr virus-associated lymphoproliferative disorder of the brain presenting as human immunodeficiency virus-associated encephalopathy in a child with acquired immunodeficiency syndrome.
Arch. Pathol. Lab. Med. 123: 83-7, 1999. [Journal]
77)  Fritsch M, Jaffe ES, Griffin C, Camacho J, Raffeld M, Kingma DW.
Lymphoproliferative disorder of fetal origin presenting as oligohydramnios.
Am. J. Surg. Pathol. 23: 595-601, 1999. [Journal]
78)  Campo E, Raffeld M, Jaffe ES.
Mantle-cell lymphoma.
Semin. Hematol. 36: 115-27, 1999. [Journal]
79)  Krenacs T, Krenacs L, Raffeld M.
Multiple antigen immunostaining procedures.
Methods Mol. Biol. 115: 223-33, 1999. [Journal]
80)  Quintanilla-Martinez L, Fend F, Moguel LR, Spilove L, Beaty MW, Kingma DW, Raffeld M, Jaffe ES.
Peripheral T-cell lymphoma with Reed-Sternberg-like cells of B-cell phenotype and genotype associated with Epstein-Barr virus infection.
Am. J. Surg. Pathol. 23: 1233-40, 1999. [Journal]
81)  Finn LS, Viswanatha DS, Belasco JB, Snyder H, Huebner D, Sorbara L, Raffeld M, Jaffe ES, Salhany KE.
Primary follicular lymphoma of the testis in childhood.
Cancer. 85: 1626-35, 1999. [Journal]
82)  Campo E, Miquel R, Krenacs L, Sorbara L, Raffeld M, Jaffe ES.
Primary nodal marginal zone lymphomas of splenic and MALT type.
Am. J. Surg. Pathol. 23: 59-68, 1999. [Journal]
83)  Elenitoba-Johnson KS, Zarate-Osorno A, Meneses A, Krenacs L, Kingma DW, Raffeld M, Jaffe ES.
Cytotoxic granular protein expression, Epstein-Barr virus strain type, and latent membrane protein-1 oncogene deletions in nasal T-lymphocyte/natural killer cell lymphomas from Mexico.
Mod. Pathol. 11: 754-61, 1998. [Journal]
84)  Gutiérrez MI, Spangler G, Kingma D, Raffeld M, Guerrero I, Misad O, Jaffe ES, Magrath IT, Bhatia K.
Epstein-Barr virus in nasal lymphomas contains multiple ongoing mutations in the EBNA-1 gene.
Blood. 92: 600-6, 1998. [Journal]
85)  Teruya-Feldstein J, Zauber P, Setsuda JE, Berman EL, Sorbara L, Raffeld M, Tosato G, Jaffe ES.
Expression of human herpesvirus-8 oncogene and cytokine homologues in an HIV-seronegative patient with multicentric Castleman's disease and primary effusion lymphoma.
Lab. Invest. 78: 1637-42, 1998. [Journal]
86)  Patel V, Senderowicz AM, Pinto D, Igishi T, Raffeld M, Quintanilla-Martinez L, Ensley JF, Sausville EA, Gutkind JS.
Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.
J. Clin. Invest. 102: 1674-81, 1998. [Journal]
87)  Elenitoba-Johnson KS, Gascoyne RD, Lim MS, Chhanabai M, Jaffe ES, Raffeld M.
Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma.
Blood. 91: 4677-85, 1998. [Journal]
88)  Quintanilla-Martinez L, Thieblemont C, Fend F, Kumar S, Pinyol M, Campo E, Jaffe ES, Raffeld M.
Mantle cell lymphomas lack expression of p27Kip1, a cyclin-dependent kinase inhibitor.
Am. J. Pathol. 153: 175-82, 1998. [Journal]
89)  Lim MS, Straus SE, Dale JK, Fleisher TA, Stetler-Stevenson M, Strober W, Sneller MC, Puck JM, Lenardo MJ, Elenitoba-Johnson KS, Lin AY, Raffeld M, Jaffe ES.
Pathological findings in human autoimmune lymphoproliferative syndrome.
Am. J. Pathol. 153: 1541-50, 1998. [Journal]
90)  Sakai A, Thieblemont C, Wellmann A, Jaffe ES, Raffeld M.
PTEN gene alterations in lymphoid neoplasms.
Blood. 92: 3410-5, 1998. [Journal]
91)  Kumar S, Krenacs L, Medeiros J, Elenitoba-Johnson KS, Greiner TC, Sorbara L, Kingma DW, Raffeld M, Jaffe ES.
Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes.
Hum. Pathol. 29: 397-403, 1998. [Journal]
92)  Krenacs L, Himmelmann AW, Quintanilla-Martinez L, Fest T, Riva A, Wellmann A, Bagdi E, Kehrl JH, Jaffe ES, Raffeld M.
Transcription factor B-cell-specific activator protein (BSAP) is differentially expressed in B cells and in subsets of B-cell lymphomas.
Blood. 92: 1308-16, 1998. [Journal]
93)  Guo HG, Browning P, Nicholas J, Hayward GS, Tschachler E, Jiang YW, Sadowska M, Raffeld M, Colombini S, Gallo RC, Reitz MS.
Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma.
Virology. 228: 371-8, 1997. [Journal]
94)  Jaffe ES, Krenacs L, Raffeld M.
Classification of T-cell and NK-cell neoplasms based on the REAL classification.
Ann. Oncol. 8 Suppl 2: 17-24, 1997. [Journal]
95)  Krenacs L, Wellmann A, Sorbara L, Himmelmann AW, Bagdi E, Jaffe ES, Raffeld M.
Cytotoxic cell antigen expression in anaplastic large cell lymphomas of T- and null-cell type and Hodgkin's disease: evidence for distinct cellular origin.
Blood. 89: 980-9, 1997. [Journal]
96)  Abruzzo LV, Griffith LM, Nandedkar M, Aguilera NS, Taubenberger JK, Raffeld M, Stass SA, Abbondanzo SL, Jaffe ES.
Histologically discordant lymphomas with B-cell and T-cell components.
Am. J. Clin. Pathol. 108: 316-23, 1997. [Journal]
97)  Wellmann A, Krenacs L, Fest T, Scherf U, Pastan I, Raffeld M, Brinkmann U.
Localization of the cell proliferation and apoptosis-associated CAS protein in lymphoid neoplasms.
Am. J. Pathol. 150: 25-30, 1997. [Journal]
98)  Elenitoba-Johnson KS, Kumar S, Lim MS, Kingma DW, Raffeld M, Jaffe ES.
Marginal zone B-cell lymphoma with monocytoid B-cell lymphocytes in pediatric patients without immunodeficiency. A report of two cases.
Am. J. Clin. Pathol. 107: 92-8, 1997. [Journal]
99)  Mansoor A, Stevenson MS, Li RZ, Frekko K, Weiss W, Ahmad M, Khan AH, Mushtaq S, Saleem M, Raffeld M, Kingma DW, Jaffe ES.
Prevalence of Epstein-Barr viral sequences and EBV LMP1 oncogene deletions in Burkitt's lymphoma from Pakistan: epidemiological correlations.
Hum. Pathol. 28: 283-8, 1997. [Journal]
100)  Kumar S, Kumar D, Kaldjian EP, Bauserman S, Raffeld M, Jaffe ES.
Primary low-grade B-cell lymphoma of the dura: a mucosa associated lymphoid tissue-type lymphoma.
Am. J. Surg. Pathol. 21: 81-7, 1997. [Journal]
101)  Wilson WH, Teruya-Feldstein J, Fest T, Harris C, Steinberg SM, Jaffe ES, Raffeld M.
Relationship of p53, bcl-2, and tumor proliferation to clinical drug resistance in non-Hodgkin's lymphomas.
Blood. 89: 601-9, 1997. [Journal]
102)  Wellmann A, Doseeva V, Butscher W, Raffeld M, Fukushima P, Stetler-Stevenson M, Gardner K.
The activated anaplastic lymphoma kinase increases cellular proliferation and oncogene up-regulation in rat 1a fibroblasts.
FASEB J. 11: 965-72, 1997. [Journal]
103)  Sander CA, Kind P, Kaudewitz P, Raffeld M, Jaffe ES.
The Revised European-American Classification of Lymphoid Neoplasms (REAL): a new perspective for the classification of cutaneous lymphomas.
J. Cutan. Pathol. 24: 329-41, 1997. [Journal]
104)  Otsuki T, Jaffe ES, Wellmann A, Kumar S, Condron KS, Raffeld M.
Absence of p18 mutations or deletions in lymphoid malignancies.
Leukemia. 10: 356-60, 1996. [Journal]
105)  Wilson WH, Kingma DW, Raffeld M, Wittes RE, Jaffe ES.
Association of lymphomatoid granulomatosis with Epstein-Barr viral infection of B lymphocytes and response to interferon-alpha 2b.
Blood. 87: 4531-7, 1996. [Journal]
106)  Kumar S, Krenacs L, Otsuki T, Kumar D, Harris CA, Wellmann A, Jaffe ES, Raffeld M.
bc1-1 rearrangement and cyclin D1 protein expression in multiple lymphomatous polyposis.
Am. J. Clin. Pathol. 105: 737-43, 1996. [Journal]
107)  Simon M, Kind P, Kaudewitz P, Graf A, Schirren CG, Raffeld M, Sander CA.
Detection of herpesvirus-like DNA in HIV-associated and classical Kaposi's sarcoma.
Arch. Dermatol. Res. 288: 402-4, 1996. [Journal]
108)  Otsuki T, Kumar S, Ensoli B, Kingma DW, Yano T, Stetler-Stevenson M, Jaffe ES, Raffeld M.
Detection of HHV-8/KSHV DNA sequences in AIDS-associated extranodal lymphoid malignancies.
Leukemia. 10: 1358-62, 1996. [Journal]
109)  Kingma DW, Shad A, Tsokos M, Fest T, Otsuki T, Frekko K, Werner E, Werner A, Magrath I, Raffeld M, Jaffe ES.
Epstein-Barr virus (EBV)-associated smooth-muscle tumor arising in a post-transplant patient treated successfully for two PT-EBV-associated large-cell lymphomas. Case report.
Am. J. Surg. Pathol. 20: 1511-9, 1996. [Journal]
110)  Kingma DW, Weiss WB, Jaffe ES, Kumar S, Frekko K, Raffeld M.
Epstein-Barr virus latent membrane protein-1 oncogene deletions: correlations with malignancy in Epstein-Barr virus--associated lymphoproliferative disorders and malignant lymphomas.
Blood. 88: 242-51, 1996. [Journal]
111)  Cooke CB, Krenacs L, Stetler-Stevenson M, Greiner TC, Raffeld M, Kingma DW, Abruzzo L, Frantz C, Kaviani M, Jaffe ES.
Hepatosplenic T-cell lymphoma: a distinct clinicopathologic entity of cytotoxic gamma delta T-cell origin.
Blood. 88: 4265-74, 1996. [Journal]
112)  Sander CA, Simon M, Puchta U, Raffeld M, Kind P.
HHV-8 in lymphoproliferative lesions in skin.
Lancet. 348: 475-6, 1996. [Journal]
113)  Clark HM, Yano T, Sander C, Jaffe ES, Raffeld M.
Mutation of the ras genes is a rare genetic event in the histologic transformation of follicular lymphoma.
Leukemia. 10: 844-7, 1996. [Journal]
114)  Hernandez L, Fest T, Cazorla M, Teruya-Feldstein J, Bosch F, Peinado MA, Piris MA, Montserrat E, Cardesa A, Jaffe ES, Campo E, Raffeld M.
p53 gene mutations and protein overexpression are associated with aggressive variants of mantle cell lymphomas.
Blood. 87: 3351-9, 1996. [Journal]
115)  Kumar S, Kingma DW, Weiss WB, Raffeld M, Jaffe ES.
Primary cutaneous Hodgkin's disease with evolution to systemic disease. Association with the Epstein-Barr virus.
Am. J. Surg. Pathol. 20: 754-9, 1996. [Journal]
116)  Keleti J, Quezado MM, Abaza MM, Raffeld M, Tsokos M.
The MDM2 oncoprotein is overexpressed in rhabdomyosarcoma cell lines and stabilizes wild-type p53 protein.
Am. J. Pathol. 149: 143-51, 1996. [Journal]
117)  Kumar S, Green GA, Teruya-Feldstein J, Raffeld M, Jaffe ES.
Use of CD23 (BU38) on paraffin sections in the diagnosis of small lymphocytic lymphoma and mantle cell lymphoma.
Mod. Pathol. 9: 925-9, 1996. [Journal]
118)  Wang J, Medeiros LJ, Longo DL, Mansoor A, Raffeld M, Duffey PL, Jaffe ES, Stetler-Stevenson M.
Use of the polymerase chain reaction technique to determine c-myc expression in follicular center cell lymphoma.
Diagn. Mol. Pathol. 5: 20-5, 1996. [Journal]
119)  Hoang AT, Lutterbach B, Lewis BC, Yano T, Chou TY, Barrett JF, Raffeld M, Hann SR, Dang CV.
A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain.
Mol. Cell. Biol. 15: 4031-42, 1995. [Journal]
120)  Otsuki T, Yano T, Clark HM, Bastard C, Kerckaert JP, Jaffe ES, Raffeld M.
Analysis of LAZ3 (BCL-6) status in B-cell non-Hodgkin's lymphomas: results of rearrangement and gene expression studies and a mutational analysis of coding region sequences.
Blood. 85: 2877-84, 1995. [Journal]
121)  Greiner TC, Raffeld M, Lutz C, Dick F, Jaffe ES.
Analysis of T cell receptor-gamma gene rearrangements by denaturing gradient gel electrophoresis of GC-clamped polymerase chain reaction products. Correlation with tumor-specific sequences.
Am. J. Pathol. 146: 46-55, 1995. [Journal]
122)  Wellmann A, Otsuki T, Vogelbruch M, Clark HM, Jaffe ES, Raffeld M.
Analysis of the t(2;5)(p23;q35) translocation by reverse transcription-polymerase chain reaction in CD30+ anaplastic large-cell lymphomas, in other non-Hodgkin's lymphomas of T-cell phenotype, and in Hodgkin's disease.
Blood. 86: 2321-8, 1995. [Journal]
123)  Raffeld M, Yano T, Hoang AT, Lewis B, Clark HM, Otsuki T, Dang CV.
Clustered mutations in the transcriptional activation domain of Myc in 8q24 translocated lymphomas and their functional consequences.
Curr. Top. Microbiol. Immunol. 194: 265-72, 1995. [Journal]
124)  Kingma DW, Raffeld M, Jaffe ES.
Differential diagnosis of CD3+, CD56+ T-cell leukemias.
Blood. 85: 1675-6, 1995. [Journal]
125)  Kolesnitchenko V, Wahl LM, Tian H, Sunila I, Tani Y, Hartmann DP, Cossman J, Raffeld M, Orenstein J, Samelson LE, Cohen DI.
Human immunodeficiency virus 1 envelope-initiated G2-phase programmed cell death.
Proc. Natl. Acad. Sci. U.S.A. 92: 11889-93, 1995. [Journal]
126)  Otsuki T, Clark HM, Wellmann A, Jaffe ES, Raffeld M.
Involvement of CDKN2 (p16INK4A/MTS1) and p15INK4B/MTS2 in human leukemias and lymphomas.
Cancer Res. 55: 1436-40, 1995. [Journal]
127)  Downing JR, Ladanyi M, Raffeld M, Weiss LM, Morris SW.
Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease.
Lancet. 345: 918; author reply 920-1, 1995. [Journal]
128)  Teruya-Feldstein J, Temeck BK, Sloas MM, Kingma DW, Raffeld M, Pass HI, Mueller B, Jaffe ES.
Pulmonary malignant lymphoma of mucosa-associated lymphoid tissue (MALT) arising in a pediatric HIV-positive patient.
Am. J. Surg. Pathol. 19: 357-63, 1995. [Journal]
129)  Whang-Peng J, Knutsen T, Jaffe ES, Steinberg SM, Raffeld M, Zhao WP, Duffey P, Condron K, Yano T, Longo DL.
Sequential analysis of 43 patients with non-Hodgkin's lymphoma: clinical correlations with cytogenetic, histologic, immunophenotyping, and molecular studies.
Blood. 85: 203-16, 1995. [Journal]
130)  Anwar N, Kingma DW, Bloch AR, Mourad M, Raffeld M, Franklin J, Magrath I, el Bolkainy N, Jaffe ES.
The investigation of Epstein-Barr viral sequences in 41 cases of Burkitt's lymphoma from Egypt: epidemiologic correlations.
Cancer. 76: 1245-52, 1995. [Journal]
131)  Hollingsworth HC, Peiper SC, Weiss LM, Raffeld M, Jaffe ES.
An investigation of the viral pathogenesis of Kikuchi-Fujimoto disease. Lack of evidence for Epstein-Barr virus or human herpesvirus type 6 as the causative agents.
Arch. Pathol. Lab. Med. 118: 134-40, 1994. [Journal]
132)  Raffeld M, Jaffe ES.
Avidin-biotin labeling of cellular antigens in cryostat-sectioned tissue.
Methods Mol. Biol. 34: 195-203, 1994. [Journal]
133)  Ensoli B, Markham P, Kao V, Barillari G, Fiorelli V, Gendelman R, Raffeld M, Zon G, Gallo RC.
Block of AIDS-Kaposi's sarcoma (KS) cell growth, angiogenesis, and lesion formation in nude mice by antisense oligonucleotide targeting basic fibroblast growth factor. A novel strategy for the therapy of KS.
J. Clin. Invest. 94: 1736-46, 1994. [Journal]
134)  Whang-Peng J, Knutsen T, Jaffe E, Raffeld M, Zhao WP, Duffey P, Longo DL.
Cytogenetic study of two cases with lymphoma of mucosa-associated lymphoid tissue.
Cancer Genet. Cytogenet. 77: 74-80, 1994. [Journal]
135)  Longo DL, Duffey PL, Jaffe ES, Raffeld M, Hubbard SM, Fisher RI, Wittes RE, DeVita VT, Young RC.
Diffuse small noncleaved-cell, non-Burkitt's lymphoma in adults: a high-grade lymphoma responsive to ProMACE-based combination chemotherapy.
J. Clin. Oncol. 12: 2153-9, 1994. [Journal]
136)  Kingma DW, Medeiros LJ, Barletta J, Raffeld M, Mann RB, Ambinder RF, Jaffe ES.
Epstein-Barr virus is infrequently identified in non-Hodgkin's lymphomas associated with Hodgkin's disease.
Am. J. Surg. Pathol. 18: 48-61, 1994. [Journal]
137)  Hollingsworth HC, Stetler-Stevenson M, Gagneten D, Kingma DW, Raffeld M, Jaffe ES.
Immunodeficiency-associated malignant lymphoma. Three cases showing genotypic evidence of both T- and B-cell lineages.
Am. J. Surg. Pathol. 18: 1092-101, 1994. [Journal]
138)  Clark HM, Yano T, Otsuki T, Jaffe ES, Shibata D, Raffeld M.
Mutations in the coding region of c-MYC in AIDS-associated and other aggressive lymphomas.
Cancer Res. 54: 3383-6, 1994. [Journal]
139)  Zarate-Osorno A, Raffeld M, Berman EL, Ferguson MM, Andrade R, Jaffe ES.
S-100-positive T-cell lymphoproliferative disorder. A case report and review of the literature.
Am. J. Clin. Pathol. 102: 478-82, 1994. [Journal]
140)  Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang HK, Brady JN, Gallo RC.
Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma.
Nature. 371: 674-80, 1994. [Journal]
141)  Jaffe ES, Zarate-Osorno A, Kingma DW, Raffeld M, Medeiros LJ.
The interrelationship between Hodgkin's disease and non-Hodgkin's lymphomas.
Ann. Oncol. 5 Suppl 1: 7-11, 1994. [Journal]
142)  Yano T, Sander CA, Clark HM, Dolezal MV, Jaffe ES, Raffeld M.
Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma.
Oncogene. 8: 2741-8, 1993. [Journal]
143)  Wang J, Raffeld M, Medeiros LJ, Longo DL, Jaffe ES, Duffey P, Stetler-Stevenson M.
Follicular center cell lymphoma with the t(14;18) translocation in which the rearranged BCL-2 gene is silent.
Leukemia. 7: 1834-9, 1993. [Journal]
144)  Sander CA, Yano T, Clark HM, Harris C, Longo DL, Jaffe ES, Raffeld M.
p53 mutation is associated with progression in follicular lymphomas.
Blood. 82: 1994-2004, 1993. [Journal]
145)  Ahmed AA, Nava VE, Pham T, Taubenberger JK, Lichy JH, Sorbara L, Raffeld M, Mackall CL, Tsokos M.
Ewing sarcoma family of tumors in unusual sites: confirmation by rt-PCR.
Pediatr. Dev. Pathol. 9: 488-95, , ,. [Journal]
146)  Kumar S, Pittaluga S, Raffeld M, Guerrera M, Seibel NL, Jaffe ES.
Primary cutaneous CD30-positive anaplastic large cell lymphoma in childhood: report of 4 cases and review of the literature.
Pediatr. Dev. Pathol. 8: 52-60, , ,. [Journal]
147)  Messineo C, Coupland R, Bakhshi A, Raffeld M, Irving SG, Bagg A, Cossman J.
Rearrangement, hypermutation, and possible preferential use of a VH5 gene, VH32, in a Hodgkin's cell line.
Hematopathology and molecular hematology. 11: 19-28, , ,. [Journal]
148)  Sarkodee-Adoo C, Pittarelli L, Jaffe E, Sorbara L, Raffeld M, Yao X, Haddad R, Heller T.
Regression and clonally distinct recurrence of human immunodeficiency virus related Burkitt-like lymphoma during antiretroviral therapy.
Leuk. Lymphoma. 42: 1125-31, , ,. [Journal]
149)  Nishizuka S, Chen ST, Gwadry FG, Alexander J, Major SM, Scherf U, Reinhold WC, Waltham M, Charboneau L, Young L, Bussey KJ, Kim S, Lababidi S, Lee JK, Pittaluga S, Scudiero DA, Sausville EA, Munson PJ, Petricoin EF, Liotta LA, Hewitt SM, Raffeld M, Weinstein JN.
Diagnostic markers that distinguish colon and ovarian adenocarcinomas: identification by genomic, proteomic, and tissue array profiling.
Cancer Res. 63: 5243-50, 2003. [Journal]
150)  Jaffe ES, Krenacs L, Raffeld M.
Classification of cytotoxic T-cell and natural killer cell lymphomas.
Semin Hematol. 40: 175-84, 2003. [Journal]
151)  Aerbajinai W, Giattina M, Lee YT, Raffeld M, Miller JL.
The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation.
Blood. 102: 712-7, 2003. [Journal]
152)  Taddesse-Heath L, Pittaluga S, Sorbara L, Bussey M, Raffeld M, Jaffe ES.
Marginal zone B-cell lymphoma in children and young adults.
Am J Surg Pathol. 27: 522-31, 2003. [Journal]
153)  Taddesse-Heath L, Feldman JI, Fahle GA, Fischer SH, Sorbara L, Raffeld M, Jaffe ES.
Florid CD4+, CD56+ T-cell infiltrate associated with Herpes simplex infection simulating nasal NK-/T-cell lymphoma.
Mod Pathol. 16: 166-72, 2003. [Journal]
154)  Toro JR, Liewehr DJ, Pabby N, Sorbara L, Raffeld M, Steinberg SM, Jaffe ES.
Gamma-delta T-cell phenotype is associated with significantly decreased survival in cutaneous T-cell lymphoma.
Blood. 101: 3407-12, 2003. [Journal]
155)  Little RF, Pittaluga S, Grant N, Steinberg SM, Kavlick MF, Mitsuya H, Franchini G, Gutierrez M, Raffeld M, Jaffe ES, Shearer G, Yarchoan R, Wilson WH.
Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology.
Blood. 101: 4653-9, 2003. [Journal]
156)  Bryant-Greenwood P, Sorbara L, Filie AC, Little R, Yarchoan R, Wilson W, Raffeld M, Abati A.
Infection of mesothelial cells with human herpes virus 8 in human immunodeficiency virus-infected patients with Kaposi's sarcoma, Castleman's disease, and recurrent pleural effusions.
Mod Pathol. 16: 145-53, 2003. [Journal]
157)  Sausville JE, Salloum RG, Sorbara L, Kingma DW, Raffeld M, Kreitman RJ, Imus PD, Venzon D, Stetler-Stevenson M.
Minimal residual disease detection in hairy cell leukemia. Comparison of flow cytometric immunophenotyping with clonal analysis using consensus primer polymerase chain reaction for the heavy chain gene.
Am J Clin Pathol. 119: 213-7, 2003. [Journal]
158)  Quintanilla-Martinez L, Davies-Hill T, Fend F, Calzada-Wack J, Sorbara L, Campo E, Jaffe ES, Raffeld M.
Sequestration of p27Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL): implications for pathogenesis.
Blood. 101: 3181-7, 2003. [Journal]
159)  Jones MB, Michener CM, Blanchette JO, Kuznetsov VA, Raffeld M, Serrero G, Emmert-Buck MR, Petricoin EF, Krizman DB, Liotta LA, Kohn EC.
The granulin-epithelin precursor/PC-cell-derived growth factor is a growth factor for epithelial ovarian cancer.
Clin Cancer Res. 9: 44-51, 2003. [Journal]
160)  Krenacs L, Smyth MJ, Bagdi E, Krenacs T, Kopper L, Rudiger T, Zettl A, Muller-Hermelink HK, Jaffe ES, Raffeld M.
The serine protease granzyme M is preferentially expressed in NK-cell, gamma delta T-cell, and intestinal T-cell lymphomas: evidence of origin from lymphocytes involved in innate immunity.
Blood. 101: 3590-3, 2003. [Journal]
161)  Wiestner A, Rosenwald A, Barry TS, Wright G, Davis RE, Henrickson SE, Zhao H, Ibbotson RE, Orchard JA, Davis Z, Stetler-Stevenson M, Raffeld M, Arthur DC, Marti GE, Wilson WH, Hamblin TJ, Oscier DG, Staudt LM.
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.
Blood. 101: 4944-51, 2003. [Journal]
162)  Akin C, Jaffe ES, Raffeld M, Kirshenbaum AS, Daley T, Noel P, Metcalfe DD.
An immunohistochemical study of the bone marrow lesions of systemic mastocytosis: expression of stem cell factor by lesional mast cells.
Am J Clin Pathol. 118: 242-7, 2002. [Journal]
163)  Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, Schwartzentruber DJ, Topalian SL, Sherry R, Restifo NP, Hubicki AM, Robinson MR, Raffeld M, Duray P, Seipp CA, Rogers-Freezer L, Morton KE, Mavroukakis SA, White DE, Rosenberg SA.
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes.
Science. 298: 850-4, 2002. [Journal]
164)  Barry TS, Jaffe ES, Kingma DW, Martin AW, Sorbara L, Raffeld M, Pittaluga S.
CD5+ follicular lymphoma: a clinicopathologic study of three cases.
Am J Clin Pathol. 118: 589-98, 2002. [Journal]
165)  Goebel SU, Iwamoto M, Raffeld M, Gibril F, Hou W, Serrano J, Jensen RT.
Her-2/neu expression and gene amplification in gastrinomas: correlations with tumor biology, growth, and aggressiveness.
Cancer Res. 62: 3702-10, 2002. [Journal]
166)  Peghini PL, Iwamoto M, Raffeld M, Chen YJ, Goebel SU, Serrano J, Jensen RT.
Overexpression of epidermal growth factor and hepatocyte growth factor receptors in a proportion of gastrinomas correlates with aggressive growth and lower curability.
Clin Cancer Res. 8: 2273-85, 2002. [Journal]
167)  Lim MS, Beaty M, Sorbara L, Cheng RZ, Pittaluga S, Raffeld M, Jaffe ES.
T-cell/histiocyte-rich large B-cell lymphoma: a heterogeneous entity with derivation from germinal center B cells.
Am J Surg Pathol. 26: 1458-66, 2002. [Journal]
168)  Ishibe N, Prieto D, Hosack DA, Lempicki RA, Goldin LR, Raffeld M, Marti GE, Caporaso NE.
Telomere length and heavy-chain mutation status in familial chronic lymphocytic leukemia.
Leuk Res. 26: 791-4, 2002. [Journal]
169)  Sakai A, Marti GE, Caporaso N, Pittaluga S, Touchman JW, Fend F, Raffeld M.
Analysis of expressed immunoglobulin heavy chain genes in familial B-CLL.
Blood. 95: 1413-9, 2000. [Journal]
170)  Gutiérrez MI, Kingma DW, Sorbara L, Tran M, Raffeld M, Jaffe ES, Magrath I, Bhatia K.
Association of EBV strains, defined by multiple loci analyses, in non-Hodgkin lymphomas and reactive tissues from HIV positive and HIV negative patients.
Leuk Lymphoma. 37: 425-9, 2000. [Journal]
171)  Fend F, Quintanilla-Martínez L, Raffeld M.
Composite lymphoma.
Hum Pathol. 31: 626-7, 2000. [Journal]
172)  Wellmann A, Thieblemont C, Pittaluga S, Sakai A, Jaffe ES, Siebert P, Raffeld M.
Detection of differentially expressed genes in lymphomas using cDNA arrays: identification of clusterin as a new diagnostic marker for anaplastic large-cell lymphomas.
Blood. 96: 398-404, 2000. [Journal]
173)  Kumar S, Fend F, Quintanilla-Martinez L, Kingma DW, Sorbara L, Raffeld M, Banks PM, Jaffe ES.
Epstein-Barr virus-positive primary gastrointestinal Hodgkin's disease: association with inflammatory bowel disease and immunosuppression.
Am J Surg Pathol. 24: 66-73, 2000. [Journal]
174)  Quintanilla-Martinez L, Kumar S, Fend F, Reyes E, Teruya-Feldstein J, Kingma DW, Sorbara L, Raffeld M, Straus SE, Jaffe ES.
Fulminant EBV(+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome.
Blood. 96: 443-51, 2000. [Journal]
175)  Toro JR, Beaty M, Sorbara L, Turner ML, White J, Kingma DW, Raffeld M, Jaffe ES.
gamma delta T-cell lymphoma of the skin: a clinical, microscopic, and molecular study.
Arch Dermatol. 136: 1024-32, 2000. [Journal]
176)  Wilson WH, Sorbara L, Figg WD, Mont EK, Sausville E, Warren KE, Balis FM, Bauer K, Raffeld M, Senderowicz AM, Monks A.
Modulation of clinical drug resistance in a B cell lymphoma patient by the protein kinase inhibitor 7-hydroxystaurosporine: presentation of a novel therapeutic paradigm.
Clin Cancer Res. 6: 415-21, 2000. [Journal]

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