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PUMA2 -- Evolutionary Analysis of Metabolism | |
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PUMA2 is not being maintained or updated by Argonne National Laboratory and will be taken down in the near future. If there is any data here that you wish to preserve, you are responsible for downloading it. An overview of the bioinformatics research being conducted at the Mathematics and Computer Science Division is available at this page. |
| EC-number: 3.6.3.9 ----- Na+/K+-exchanging ATPase |
| EC-NUMBER | 3.6.3.9 | |
| ENZYME-NAME | Na+/K+-exchanging ATPase | |
| ENZYME-SYSNAME | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This is a plasma membrane enzyme, ubiquitous in animal cells, that catalyses the efflux of three Na+ and influx of two K+ per ATP hydrolysed. It is involved in generating the plasma membrane electrical potential. | |
| ENZYME-CLASS | Hydrolases Acting on acid anhydrides Catalysing transmembrane movement of substances | |
| SYNONYMS | (Na+ + K+)-ATPase;; (Na+ + K+)-activated ATPase;; Na+,K+ pump;; Na+,K+-ATPase;; >>more synonyms | |
| REACTION | ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in) | |
| PATHWAY | EMP-PATHWAYS: Na(''+),K(''+)(,extracellular)--Na(''+)(,extracellular),_K(''+)_Membrane_transport_(ATP)_(plasma_membrane); >>more EMP pathways | |
| KEGG-PATHWAYS: NO KEGG PATHWAY FOUND | ||
| GO_TERM | GO:0005391:sodium:potassium-exchanging ATPase activity | |
| ENZYME-COMMENT | ATP phosphohydrolase (Na+/K+-exchanging) | |
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To perform phylogenetic analysis:
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