Additional publications from Dr. Miriam Anver:

Sun, K., Wilkins, D.E.C., Anver, M.R. , Sayers, T.J., Panoskaltsis-Mortari, A., Blazar, B.R., Welniak, L.A. , Murphy, W.J. Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity. Blood;106:3293-3299, 2005

Raafat, A., Bargo, S., Anver, MR. , Callahan, R. Mammary Development and Tumorigenesis in Mice Expressing a Truncated Human Notch4/Int3 Intracellular Domain (h-Int3sh). Oncogene 2004; 23: 9401-9407.

Welniak, L.A, Wang, Z., Sun, K., Kuziel, W., Anver, M.R. , Blazar, B.R., Murphy, W.J. An absence of CCR5 on donor cells results in acceleration of acute graft-versus-host disease. Experimental Hematology 2004; 32: 318-324.

Wolff, L., Garin, M.T., Koller, R., Bies, J., Tessarollo, L., Anver, M.R. , Powell, D., Perella, C. A novel retrovirus provides the cooperating oncogenic event(s) required to demonstrate the tumor suppressor activity of p15 Ink4b in myeloid cells in vivo. Blood Cells, Molecules, and Diseases 2004; 32: 226-231.

Hixon, J.A., Anver, M.R. , Blazar, B.R., Panoskaltsis-Mortari, A., Wiltrout, R.H., Murphy, W.J. Administration of Either Anti-CD40 or Interleukin-12 following Lethal Total Body Irradiation Induces Acute Lethal Toxicity Affecting the Gut. BBMT 2002; 8: 316-325.

Wolff, L., Koller, R., Hu, X., Anver, M.R. A moloney murine leukemia virus-based retrovirus with 4070A long terminal repeat sequences induces a high incidence of myeloid as well as lymphoid neoplasms. Journal of Virology 2003; 77(8): 4965-4971.

Yang, Y., Dukhanina, O., Tang, B., Mamura, M., Letterio, J., MacGregor, J., Patel, S., Khozin, S., Green, J., Anver, M ., Merlino, G., Wakefield , L. Lifetime exposure to a soluble TGF-B antagonist protects mice against metastasis without adverse side-effects. J Clin Invest 2002; 109: 1607-1615.

Couldrey, C., Moitra, J., Vinson, C., Anver, M. , Nagashima, K., Green, J. Adipose tissue: a vital in vivo role in mammary gland development but not differentiation. Developmental Dynamics 2002; 223: 459-468.

Green, J.E., Shibata, M.-A., Shibata, E., Moon, R., Anver, M.R. , Kelloff, G., Lubet, R. 2-Difluoromethylornithine and dehydroepiandrosterone inhibit mammary tumor progression but not mammary or prostate tumor initiation in C3(1)/SV40 T/t-antigen transgenic mice. Cancer Research 2001; 61: 7449-7455.

Hixon, J.A., Blazar, B.R., Anver, M.R. , Wiltrout, R.H., Murphy, W.F. Antibodies to CD40 Induce a Lethal Cytokine Cascade After Syngeneic Bone Marrow Transplantation. Biology of Blood and Marrow Transplantation 7:136-143, 2001

Ward, J.M., Yoon, M., Anver, M.R. , Haines , D.C. , Kudo, G., Gonzalez, F.J., Kimura, S. Hyalinosis and Ym1/Ym2 gene expression in the stomach and respiratory tract of 129S4/SvJae and wild-type and CYP1A2-null B6,129 mice. American Journal of Pathology 158:323-332, 2001

Josyula, S., Schut, H.A.J., Diwan, B.A., Anver, M.R. , Anderson, L.M. Age-related alterations in 32 P-postlabeled DNA adducts in livers of mice infected with the tumorigenic bacterial pathogen, Helicobacter hepaticus . International Journal of Oncology 17:811-818, 2000.

Noonan, F.P, Otsuka, T., Bang, S., Anver, M.R. , Merlino, G. Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice. Cancer Research 60:3738-3743, 2000.

Waalkes, M., Anver, M. , Diwan, B. Carcinogenic Effects of Cadmium in the Noble (NBL/Cr) Rat: Induction of Pituitary, Testicular, and Injection Site Tumors and Intraepithelial Proliferative Lesions of the Dorsolateral Prostate. Toxicological Sciences 52:154-161, 1999.

Sullivan, T., Escalante-Alcalde, D., Bhatt, H., Anver, M. , Bhat, N., Nagashima, K., Stewart, C., Burke, B. Loss of A-Type Lamin Expression Compromises Nuclear Envelope Integrity Leading to Muscular Dystrophy. The Journal of Cell Biology Vol. 147,

No. 5:913-919, 1999.

Halverson, D., Resau, J., Faletto, D., Fisher, R., Anver, M. , Rong, S., May, J., Tsarfaty, I. , Blair, D. A Mouse Fibroblast Line Cycles Between Monolayer and Spheroid Forms, Regulates Met and Hgf Expression, and Releases an Attachment and Growth-Promoting Substance. Cell Biology International Vol. 23, No.4:257-274, 1999.

Salcedo, R., Wasserman, K., Young, H., Grimm, M., Howard, O., Anver, M. , Murphy, W., Oppenheim, J. Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells. Amer. J. of Path.

154(4): 1125-35, 1999.

McKenna, I. , Melo, Gordon, T., Chen, L., Anver, M. , Waalkes, M. Expression of Metallothionein Protein in the Lungs of Wistar Rats and C57 and DBA Mice Exposed to Cadmium Oxide Fumes. Toxicol. Appl. Pharmacol. 153:169-178, 1998.

Jeffers, M., Fiscella, M., Webb, C.P., Anver, M. , Koochekpour, S., Vande Woude, G.F. The Mutationally Activated Met Receptor Mediates Motility and Metastasis. Proc. Natl. Acad. Sci. 95:14417-14422, 1998.

Otsuka, T., Takayama, H., Sharp, R., Celli, G., LaRochelle, W., Bottaro, D., Ellmore, N., Vieira, W., Owens, J., Anver, M. , Merlino, G. c-Met Autocrine Activation Induces Development of Malignant Melanoma and Acquisition of the Metastatic Phenotype. Cancer Research 58:5157-5167, 1998.

Taylor , G., Jeffers, M., Webb, C., Koo, H., Anver M. , Sekiguchi, K., Lechleider, R., Roberts, A., Vande Woude, G. Decreased Fibronectin Expression in Met/HGF-mediated Tumorigenesis. Oncogene 17:1179-1183, 1998.

Franzoso, G., Carlson, L., Poljak, L., Shores, E., Epstein, S., Leonardi, A., Grinberg, A., Tran, T., Scharton-Kersten, T., Sher, A., Anver, M. , Love, P., Brown, K., Siebenlist, U. Mice Deficient in Nuclear Factor (NF)-?B/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture. Journal of Experimental Medicine Vol. 187, No. 2:147-159, 1998.

Tang, B., Bottinger E., Jakowlew, S., Bagnall, K., Mariano, J., Anver, M. , Letterio, J., Wakefield , L. Transforming Growth Factor-ß1 is a New Form of Tumor Suppressor with True Haploid Insufficiency. Nature Medicine Vol. 4, No. 7:802-807, 1998.

Franzoso, G., Carlson, L., Scharton-Kersten, T., Shores, E., Epstein, S., Grinberg, A., Tran, T., Shacter, E., Leonardi, A., Anver, M. , Love, P., Sher, A., Siebenlist, U. A Critical Role for the Bcl-3Oncoprotein in Development of Germinal Centers and Adaptive Immunity. Immunity Vol. 6, 479-490, 1997.

Sipowicz, M., Chomerat, P., Diwan, B., Anver, M. , Awasthi, Y., Ward, Rice, J., Kasprzak, K., Wild, C., Anderson , L. Increased Oxidative DNA Damage and Hepatocyte Overexpression of Specific Cytochrome P450 Isoforms in Livers of Mice Infected with Helicobacter hepaticus. Am. Journal Pathol., Vol. 151, No. 4:933-941, 1997.

Takayama, H., LaRochelle, W., Sharp, R., Kriebel, P., Anver, M. , Aaronson, S., Merlino, G. Diverse Tumorigenesis Associated with Aberrant Morphogenesis in Mice Overexpressing Hepatocyte Growth Factor/Scatter Factor. Proc. Natl. Acad. Sci. USA Medical Sciences 94;701-706, 1997.

Funakoshi, S., Taub, D.D., Anver, M. , Raziuddin, A., Turkovski-Corrales, S., Fanslow, W., Longo, D., Murphy, W. Immunologic and Hematopoietic Effects of Recombinant Soluble CD-40 Ligand after Syngeneic Bone Marrow Transplantation in Mice. J. of Clin. Inv. 99(3):484-491, 1997.

Chomarat, P., Sipowicz, M., Diwan, B., Fornwald, L., Awasthi, Y., Anver, M ., Rice, J., Anderson , L., Wild, C. Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus. Carcinogenesis 18(11): 2179-2190, 1997.

Funakoshi, S., Taub, D.D., Anver, M. , Raziuddin, A., Turkovski-Corrales, S., Fanslow, W., Longo, D., Murphy, W. Immunologic and Hematopoietic Effects of Recombinant Soluble CD-40 Ligand after Syngeneic Bone Marrow Transplantation in Mice. J. Clinical Invest. 99:484-491, 1997.

Colon , K., Anver, M. , Long, D., Ortaldo, J., Murphy, W. Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T cell infiltration into human melanoma xenografts. Journal of Immunotherapy 19(5):317-323, 1996.

Jeffers, M., Rong, S., Oskarsson, M., Anver, M. , Vande Woude, G. Autocrine Hepatocyte Growth Factor/Scatter Factor Signaling Induces Transformation and the Invasive/Metastatic Phenotype in C127 Cells. Oncogene 13; 853-861, 1996.

Taub, D., Anver, M. , Oppenheim, J., Longo, D., Murphy, W. T Lymphocyte recruitment by interleukin-8 (IL-8) IL-8-Induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both In Vitro and In Vivo. J. Clin. Inv. Vol. 97, No.8: 931-1941, 1996.

Takayama, H., LaRochelle, W., Anver, M. , Bockman, D., Merlino, G. Hepatocyte Growth Factor/Scatter Factor as a Regular of Skeletal Muscle and Neural Crest Development. Proc. Natl. Acad. Sci. Vol.93:5866-5871, 1996.

Bebee, L., Fornwald, L., Diwan, Bhalchandra, Anver, M. , Anderson, L. Promotion of N -Nitrosodiethylamine-initiated Hepatocellular Tumor and Hepatoblastomas by 2,3,7 & 8-Tetrachlorodibenzo- p -dioxin or Aroclor 1254 in C57BL/6, DBA/2, and B6D2F1 Mice Cancer Research 55;4875-4880, 1995.

Lucia, S.M., Anzano, M., Slayter, M., Anver, M. , Green, D., Shrader, M., Logsdon, D., Driver, C., Brown, C., Peer, C., Roberts, A., Sporn, M. The Chemopreventive Activity of Tamoxifen, N-(4-hydroxyphenyl) Rentiamide, and the Vitamin D Analogue Ro24-5531 for Androgen-promoted Carcinomas of the Rat Accessory Sex Gland. Cancer Research Vol.55:5621-5627, 1995.

Xu, L., Badolato, R., Murphy, W.J., Longo, D.L., Anver, M.R. , Hale, S.R., Oppenheim, J.J. and Wang, J.M. A Novel Biologic Function of Serum Amyloid A. The Journal of Immunology, 155:1184-1190, 1995.

Taub, D.D., Proost, P., Murphy, W.J., Anver, M.R. , Longo, D.L., Damme, J.V. Monocyte Chemotactic Protein-1 (MCP-1), -2 and -3 are Chemotactic for Human T Lymphocytes. The Journal of Clinical Investigation, Inc., Vol.95:1370-1376, 1995.

Beebe, L.E., Anver, M.R. , Riggs, C.W., Fornwald, L.W., and Anderson , L.M. Promotion of N-nitrosodimethylamine-initiated mouse lung tumors following single low or multiple low-doses exposure to 2,3,7,8 - tetrachlorobenzo-p-dixion. Carcinogenesis. Vol.16:6,1345-1349, 1995.

Coa, X., Shores, E.W., I-lu-Li, Anver, M.R. , et al. Defective lymphoid development in mice lacking expression of the common cytokine receptor ? chain. Immunity Vol.2:223-238, 1995.

Ward, J.M., Anver, M.R. , Haines , D.C. and Benveniste, R.E. Chronic active hepatitis in mice caused by Helicobacter hepaticus. Amer. J. Path. 145:959-968, 1994.

Murphy, W.J., Durum, S.K., Anver, M.R. , Ferris, D.K., et al. Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immunodeficiency (SCID). J. Immunol. 153:1004-1014, 1994.

Lijinsky, W., Pegg, A.E., Anver, M.R. and Moschel, R.C. The effects of inhibition of O 6 alkylguanine-DNA alkyltransferase in rats on carcinogenesis by methylnitrosourea and ethylnitrosourea. Jap. Journal Cancer Res. 85:226-230, 1994.

Rong, S., Segal, S., S. Anver, M. , Resau, J. and Vande Woude, G. Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. Proc. Natl. Acad. Sci. 91:4731-4735, 1994.

Maroulakou, I.G., Anver, M.R. , Garrett, L.J. and Green, J.E. Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) SV40T fusion gene. Proc. Natl. Acad. Sci. 91:11236-11240, 1994.

Murphy, W.J., Taub, D.D., Anver, M.R. , Oppenheim, J.J., Kelvin, D.J. and Longo, D.L. Human RANTES induces the migration of human T Lymphocytes into the peripheral tissues of mice with severe combined immune deficiency (SCID). Euro J. Immunol. 24:1823-1827, 1994.

Edens, L.M., Morris, D.D., Prasse, K.W., Anver, M.R. Hypercoaguable State Associated with a Deficiency of Protein C in a Thoroughbred Colt. Journal of Veterinary Internal Medicine 1993; 7: 190-193.

Takagi, T., Sharp, R., Takayama, H., Anver, M. , Ward, J. and Merlino, G. Collaboration between growth factors and diverse chemical carcinogens in hepatocarcinogenesis. Cancer Research 53:4329-4336, 1993.

Murphy, W.J., Durum, S.K., Anver, M.R. and Longo, D.L. Recombinant Human Growth Hormone Promotes Human Lymphocyte Engraftment in Immunodeficient Mice and Results in the Increased Occurrence of Human Epstein Barr Virus-Induced Lymphoma. Brain Behavior and Immunity 6:355-364, 1992.

Murphy, W., Bennett, M., Anver, M. , Back, T., Baseler, M., Wiltrout, R. and Longo, D. Human-Mouse Lymphoid Chimeras: Host-Versus-Graft and Graft-Versus-Host Reactions. European Journal of Immunology 22:1421-1427, 1992.

Murphy, W., Durum, S., Anver, M. and Longo, D. Immunologic and Hematologic Effects of Neuroendocrine Hormones. Studies on DW/J dwarf mice. Journal of Immunology 148:2799-3805, 1991.

Edens , L.M., Taylor , D.D., Murray , M.J., Spurlock, G.H. and Anver, M.R. Intestinal myxosarcoma in a thoroughbred mare. Cornell Vet. 82:163-167, 1992.

Furr, M.O., Anver, M.R. , and Wise, M. Intervertebral disk prolapse and diskospondylitis in a horse. JAVMA 198:2095-2096, 1991.

Voytek, P., Anver, M. , Thorslund, T., Conley, J. and Anderson, E. Mechanisms of asbestos carcinogenicity. J. Amer. Col. Toxicol. 9:541-550, 1990.

Smiler, K.L., Brady, A.N. and Anver, M.R. Histopathological effects of chronic exposure of Fischer 344 rats to low levels of ozone. GMR-6355, General Motors Research Laboratories, Warren , Michigan , 1988.

Cohen, B.J., Crisp, C.E., McClatchey, K.D. and Anver, M.R. Age and strain associated dysplasia of mouse maxillary incisor teeth. Gerodontology 2:43-50, 1983.

Wilcke, B.W., Newcomer, C.E., Anver, M.R. , Simmons, J.L. and Nace, G.W. Isolation of Chlamydia psittaci from African clawed frogs (Xenopus laevis). Infect. Immun. 41:789-794, 1983.

Walker , S.E. and Anver, M.R. High incidence of neoplasms in female NZB/NZW mice treated with pulse doses of cyclophosphamide. Vet. Immunol. Immunopathol.

5:97-104, 1983.

Anver, M.R. , Cohen, B.J., Lattuada, C.P. and Foster, S.J. Age-associated lesions in barrier=reared male Sprague-Dawley rats: A comparison between Hap:(SD) and Crl:CD BS(R)(SD) stocks. Exp. Aging Res. 8:1-24, 1982.

Newcomer, C.B.. Anver, M.R. , Simmons, J.R., Wilcke, B.W. and Nace, G.W. Chlamydiosis in the African clawed frog (Xenopus laevis). Lab. Anim. Sci. 32:680-686, 1982.

Pond, C.L., Newcomer, C.E. and Anver, M.R. Acute gastric dilatation in nonhuman primates: Review and case studies. Vet. Pathol. 19(Suppl.7): 126-132, 1982.

Anderson, L.C., Fiedler, V., Cohen, B.J., Anver, M.R. , Simmons, J.L. and Lucchesi, B.R. Diagnostic exercise: Pheochromocytoma in a dog. Lab. Anim. Sci. 32:141-142, 1982.

Anver. M.R. Diagnostic exercise: Chromomycosis in Rana pipiens. Lab. Anim. Sci. 30:165-166, 1980.

Doepel, F.M., Anver, M.R. and Hofing, G.L. Pancreatitis in two New World monkeys. Vet. Pathol. 17:505-508, 1980.

Olson, L.C. and Anver, M.R. "Ovarian stromal sarcoma in a guinea pig. Vet. Pathol. 17:246-248, 1980.

Olson, L.C. and Anver, M.R. Chylothorax in rhesus monkeys with intravenous catheters. Lab. Anim. Sci. 29:791-796, 1979.

Brenniman, G.R., Anver, M.R. , Hartung, R. and Rosenberg , S.H. Effects of outboard motor exhaust emissions on goldfish (Carassius auratus). J. Environ. Pathol. Toxicol. 2:791-796, 1979.

Walker , S.E. and Anver, M.R. Accelerated appearance of neoplasms in female NZB/NZW mice treated with high dose cyclophosphamide. Arthritis Rheum. 22:1338-1343, 1979.

Anver, M.R. , and Cohen, B.J. Lesions associated with aging. In Baker, H., et al., eds. The Laboratory Rat. Vol. I. Academic Press, New York , 1979.

Walker , S.E. and Anver, M.R. Stimulated autoantibody response and increased longevity in NZB/NZW mice treated with cyclophosphamide and tilorone. Clin. Exp. Immunol. 33:453-462, 1978.Cohen, B.J., Anver, M.R. , Ringler, D.H. and Adelman, R.C. Age-associated pathological changes in male rats. Fed. Proc. 37:2848-2850, 1978.

Walker , S.E., Anver, M.R. , Schecter, S.L. and Bole, G.G. Prolonged lifespan and high incidence of neoplasms in NZB/NZW mice treated with hydrocortisone sodium succinate. Kidney Int. 14:151-157, 1978.

Rhodin, A.G.J. and Anver, M.R. Mycobacteriosis in turtle: Cutaneous and hepatosplenic involvement in a Phrynops hilari. J. Wildl. Dis. 13:180-183, 1977.

Sly, D.L., Ringler, D.H. and Anver, M.R. Spontaneous histiocytic sarcoma with metastasis in a rhesus monkey (Macaca mulatta). J. Med. Primatol. 6:43-49, 1977.

Volker, F.A., Anver, M.R. , McKee, A.E., Casey, H.W. and Brenniman, G.R. Amebiasis in goldfish. Vet Pathol. 14:247-255, 1977.

Cohen, B.J. and Anver, M.R. Pathological changes during aging in rats. In Elias, M.R., Eleftherious, B.E., and Elias, P.K., eds. Special Review of Experimental Aging Research. EAR, Inc. Bar Harbor , Maine . pp. 379-406, 1977.

Anver, M.R. A typical day in a lab animal medicine unit. Lab. Anim. 5:4-6, 1976.

Anver, M.R. , Park, J.S., and Rush, H.G. Dermatophilosis in marble lizards (Calotes mystaceus). Lab. Anim. Sci. 26:817-823, 1976.

Anver, M.R. and Cohen, B.J. An animal model of human disease: Ulcerative colitis in guinea pigs induced with degraded carrageenan. Am. J. Pathol 84:431-434, 1976.

Corbett, T.H., Beaudoin, A.R., Cornell, R.G., Anver, M.R. , Schmacher, R., Endres, J. and Szwabowska, M. Toxicity of polybrominated biphenyls (Firemaster BP.6) in rodents. Environ. Res. 10:390-396, 1975.

Kluger, M., Ringler, D.H. and Anver, M.R. Fever and survival. Science 188:166-168, 1975.

Daniel, M.D., Melendez, L.V., Hunt, R.D., King, N.W., Anver, M.R. , Fraser, C.E.O. Barahona, H.H. and Baggs, R.B. Herpesvirus saimiri: VII. Induction of malignant lymphoma in New Zealand White rabbits. JNCI 53:1803-1808, 1975.

Mouw, D., Kalatis, K., Anver, M.R. , Schwartz, J., Hartung, R., Cohen, B., Constan, A. and Ringler, D. Lead: Possible toxicity in urban versus rural rats. Arch. Environ. Health 30:276-280, 1975.

Van der Waaij, D., Cohen, B.J., and Anver, M.R. Mitigation of experimental inflammatory bowel disease in guinea pigs by selective elimination of the aerobic gram negative flora. Gastroenterology 67:460-472, 1974.

Rush, H.G., Anver, M.R. and Beneke, E.S. Systemic chromomycosis in Rana pipiens. Lab. Anim. Sci. 24:646-655, 1974.

Price, R.A., Anver, M.R. and Hunt, R.D. Simian neonatology: III. The causes of neonatal mortality. Vet. Pathol. 10:37-44, 1973.

Anver, M.R. , Hunt, R.D. and Price, R.A. Simian neonatology: II. Neonatal pathology. Vet Pathol 10:16-36, 1973.

Price, R.A., Anver, M.R. and Garcia, F.G. Simian neonatology: I. Gestational maturity and extrauterine viability. Vet. Pathol. 9:301-309, 1972.

Anver, M.R. , King, N.W., and Hunt, R.D. Congenital encephalitozoonosis in Saimiri sciureus. Vet. Pathol. 9:475-480, 1972.

Anver, M.R. , Hunt, R.D. and Chalifoux, L.V. Cholesterol gallstones in Aotus trivirgatus. J. Med. Primatol. 1:241-246, 1972.