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March 8 to March 12, 2004

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AT A GLANCE - MEETINGS AT NIST

MONDAY - 3/8
10:00 AM - Nanometer Localization of Single Green Fluorescent Proteins: Evidence that Myosin V Walks Hand-over-Hand via Telemark Configuration
10:30 AM - Sub-nm resolution scanning tunneling spectroscopy magnetic imaging of bct-Mn(001) films and Fe/Mn/Fe(001) multilayer
TUESDAY - 3/9
10:30 AM - Generative Ontologies For Knowledge Extraction From Text
WEDNESDAY - 3/10
10:30 AM - Quantum Measurements and Standards Based on Condensed Matter Physics
10:45 AM - Computational Studies of Chaperonin-Mediated Protein Folding
1:00 PM - Fluctuations and Noise in Magnetic Multilayer Devices
THURSDAY - 3/11
No Scheduled Events
FRIDAY - 3/12
10:30 AM - Cluster Expansions for Disordered Systems
10:30 AM - Sparks of a Life in Physics

MEETINGS AT NIST

3/8 -- MONDAY

10:00 AM - OPTICAL TECHNOLOGY DIVISION SEMINAR: Nanometer Localization of Single Green Fluorescent Proteins: Evidence that Myosin V Walks Hand-over-Hand via Telemark Configuration
Myosin V is a homodimeric motor protein involved in trafficking of vesicles in the cell. It walks bipedally along actin filaments, moving its cargo ~37 nm per step. We have measured the step size of individual myosin heads by fusing an enhanced green fluorescent protein (eGFP) to the N-terminus of one head of the myosin dimer and following the motion with nanometer precision and sub-second resolution. We find the average step size to be 73.7 nm with a standard deviation of 8 nm and standard error of 0.4 nm. Our measurements demonstrate nanometer localization of single eGFPs, confirm the hand-over-hand model of myosin V procession, and when combined with previous data, suggest that there is a kink in the leading lever arm in the waiting state of myosin V. This kinked, or "telemark skier," configuration may cause strain, which, when released, drags the rear head forward and leads to unidirectional motion.
Greg Snyder , Department of Physics, University of Illinois.
Physics Building, Room A366. (NIST Contact: Lori Goldner, 301-975-3792, lsg@nist.gov)


10:30 AM - ELECTRON AND OPTICAL PHYSICS DIVISION SEMINAR: Sub-nm resolution scanning tunneling spectroscopy magnetic imaging of bct-Mn(001) films and Fe/Mn/Fe(001) multilayer
Spin-polarized scanning tunneling microscopy (SP-STM) can be used to image magnetic domain structures down to the atomic level. This allows us to study in detail nano-magnetism in interesting thin film systems. We demonstrate that by using W tips coated with thin Fe films, we are able to image the antiferromagnetic coupling of ferromagnetic body-centered tetragonal (bct) (001) Mn films on Fe(001). Spectroscopic images show a clear magnetic contrast on the Mn layers (>3 ML) with a period of two layers. Using this sample we found that the magnetic resolution in our setup is better than <0.5 nm. In this communication, we show that this magnetic contrast is caused by a spin-dependent peak at +0.8 eV above the Fermi energy in the spectroscopy measurements. Using band structure calculations we find 100 % spin-polarized dz2 surface states on the bct Mn(001) surface around this voltage, which are at the origin of the magnetic contrast in our measurements. Important is that we can get quantitative spin-polarized information by using the normalization by the tunneling probability function.
Toyokazu Yamada , Physicist, NSRIM University of Nijmegen.
221 Bldg, Rm. B145. (NIST Contact: Daniel Pierce, 301-975-3711, daniel.pierce@nist.gov)



3/9 -- TUESDAY

10:30 AM - ITL SEMINAR SERIES: Generative Ontologies For Knowledge Extraction From Text
Development of intelligent decision support systems can be accelerated by knowledge extraction, which aims to automatically populate complex schemas such as cases, lessons, and plans from text documents. In contrast to traditional information extraction techniques that use shallow natural language processing techniques and simple lexicons, knowledge extraction requires a combination of deep natural language techniques and rich lexical resources, which must support robust and accurate interpretation of specialized subject matter text. Popular lexical resources such as WordNet and ontologies such as CyC are representationally inadequate and largely incomplete for processing text in specialized domains (i.e., sublanguage). Consequently, we have extended generative lexicon theory and created one of its first implementations, called generative Sublanguage Ontologies (SO), which provides a rich representation for selecting unanticipated meanings of terms and their novel combinations by applying a small set of sense generation operators. I will describe SO concept representations that include novel entity and event structures within an object-oriented inheritance framework. I will discuss a methodology for representing world knowledge in SO for better interpretation of compound nouns and resolve prepositional attachments. In addition, I will show how SOs concept representation enables morphological semantics to significantly reduce its size and improve text interpretation. Finally, I will describe tools and methodologies to engineer SOs for naval knowledge extraction. Dr. Kalyan Gupta is a Chief Scientist with ITT Industries. He conducts interdisciplinary research for NRL’s IDA Group, focusing on applying AI techniques to knowledge-based decision support systems. Since October 2000 he has worked on the NRL project Language Understanding for Interactive Knowledge Management, where he is focusing on mixed-initiative case-based reasoning (CBR), information extraction, knowledge management, lexicon engineering, document restructuring, and knowledge-based project planning. He previously was Head of Research and Development at CaseBank Technologies Inc., whose product is based on his PhD research. He has authored three U.S. patents, and has published articles in journals such as IEEE Transactions on Systems Man Cybernetics, Decision Support Systems, and Omega, and in reputed national and international conferences. Dr. David Aha leads NRL’s Intelligent Decision Aids (IDA) Group, whose focus is on the research and development of state-of-the-art decision aiding tools that can be transitioned to their sponsors’ organizations. He currently lead and/or participates in projects concerning intelligent lessons learned systems, deviation detection for crisis action planning, hypothesis elaboration for suspected terrorist activities, machine learning testbed for (war)gaming systems, plan de-confliction and air vehicle management, and automated on-road driving simulation. David has published approximately 90 technical contributions, given keynote presentations at several international technical conferences, (co-)organized 13 international conferences/workshops, has served on the editorial boards for JAIR, Machine Learning, and Applied Intelligence, (co-)edited two special journal issues, and serves on several AI conference program committees.
Dr. Kalyan Moy Gupta , Advanced Engineering and Sciences; ITT Industries. Project Introduction by: Dr. David W. Aha, Intelligent Decision Aids Group Naval Research Laboratory
Administration Bldg, Lecture Rm. A. (NIST Contact: Larry Reeker, 301-975-5147, larry.reeker@nist.gov)



3/10 -- WEDNESDAY

10:30 AM - SIGMA XI LECTURE: Quantum Measurements and Standards Based on Condensed Matter Physics
A metrologist often looks for small, naturally occurring quanta to use as rulers. Time is measured by counting oscillations in a cesium atom; length, by the number of wavelengths of a laser beam. A seemingly very tangible example is length determined by the number of atomic planes in nearly perfect silicon crystals. Condensed-matter physics reveals other quanta in low temperature materials such as superconductors. Drawing on work on these systems by my colleagues at NIST and elsewhere, I will describe how they lead to voltage standards, current and capacitance standards, Johnson noise thermometry, and ultra-sensitive arrays of infrared and x-ray sensors.
Richard Harris , Quantum Electrical Metrology Division, NIST.
Administration Building, Green Auditorium. (NIST Contact: Alan Cookson, 301-975-2220, alan.cookson@nist.gov)


10:45 AM - NIST CENTER FOR NEUTRON RESEARCH SEMINAR: Computational Studies of Chaperonin-Mediated Protein Folding
George Stan , NHLBI, National Institutes of Health, Bethesda, MD.
235 Bldg, Rm. E100. (NIST Contact: Susan Krueger, 301-975-6734, susan.krueger@nist.gov)


1:00 PM - ELECTRON AND OPTICAL PHYSICS DIVISION SEMINAR: Fluctuations and Noise in Magnetic Multilayer Devices
The talk will also be videocast to Boulder Room 5000 11:00 MST Wednesday, March 10
Edmund Nowak , Department of Physics and Astronomy, University of Delaware.
Materials Bldg, Rm. B307. (NIST Contact: Mark Stiles, 301-975-3745, mark.stiles@nist.gov)



3/11 -- THURSDAY

No Scheduled Events

3/12 -- FRIDAY

10:30 AM - MATERIALS SCIENCE AND ENGINEERING LABORATORY OFFICE SEMINAR: Cluster Expansions for Disordered Systems
Marcel Sluiter , Tohoku University.
Materials Building, Rm. B307. (NIST Contact: Benjamin Burton, 301-975-6043, benjamin.burton@nist.gov)


10:30 AM - NIST COLLOQUIUM SERIES: Sparks of a Life in Physics
Dr. Khalatnikov, the Founder and Honorary Director of the L.D. Landau Institute for Theoretical Physics in Moscow, is internationally known for his scientific contributions to modern theoretical physics - from superfluidity and superconductivity theory to quantum field theory, general relativity, and cosmology. In his illustrious career, he has collaborated with some of the greatest Soviet scientists of the 20th century, including Nobel Laureates Lev Landau (1962) and Alexei Abrikosov (2003), Yeugeni Lifshitz, Yakov Zel'dovich, and others. He also participated in research related to the Soviet nuclear bomb project. In this talk he will reflect on the inspirations for his scientific contributions, the circumstances in which they were made, and his personal experiences with legendary figures of science.
Isaak Khalatnikov , Distinguished Professor, Tel-Aviv University.
Administration Bldg, Green Auditorium. (NIST Contact: Flo Parkhill, 301-975-4203, florence.parkhill@nist.gov)
Special Assistance Available



ADVANCE NOTICE

3/15/04 2:00 PM - SEMICONDUCTOR ELECTRONICS DIVISION SEMINAR: Microfabricated device for PCR by sample shunting
Despite tremendous impact in clinical diagnostics, conventional end-point and real-time quantitative (RQ) polymerase chain reaction (PCR) has near universal medical applications but suffers from intrinsic technical limitations. These restrictions include poor compatibility to study low transcript number amongst a high background of other nucleic acids, analysis of several targets from minute biopsy samples, plus additional constraints relating to time, expense and risk of cross-contamination. We are developing PCR micro-fluidic devices that will circumvent these drawbacks. Our novel approach is based on a sample-shunting system: the aqueous sample plug is shunted from one temperature zone to another by a pump system. This approach (see photo) will offer fast-cycling conditions, channel parallelization and a dimensionally favorable size and format that will ultimately derive uTAS devices for robust inter-laboratory standardization.
Pierre-Alain Auroux , Imperial College, London, UK.
Technology Building, Rm. A362. (NIST Contact: Michael Gaitan, 301-975-2070, gaitan@nist.gov) http://mems.nist.gov/Seminars/Auroux.pdf


3/16/04 12:00 PM - OFFICE OF INTERNATIONAL AND ACADEMIC AFFAIRS SEMINAR: NRC Postdoctoral Research Associates Monthly "No-Host" Brown Bag Lunch, Mar 16, 12PM, 222/B212
Dr. Jack Hsia, NIST NRC Postdoctoral Research Associateships Program Representative, Office of International and Academic Affairs, Division 109, is sponsoring monthly "no-host" brown bag lunch gatherings for NRC postdoctoral research associates. All postdocs are invited, from those newly arrived and those who may be nearing the end of their tenure at NIST. The purpose of these lunches is for NRC postdocs at NIST to get to know each other. The next no-host brown bag lunch is scheduled for March 16, 2004, 12:00pm-1:00pm, in the Division 109 conference room, building 222, room B212. Future no-host brown bag lunches are scheduled for April 20, 2004, and May 18, 2004, same location as stated above. These no-host brown bag lunches are scheduled for the third Tuesday of each month.
Dr. Jack Hsia , Chief, Academic Affairs.
222 Bldg, Rm. B212. (NIST Contact: Janice Campbell, 301-975-3076, janice.campbell@nist.gov) http://www.national-academies.org/rap; http://www.nist.gov/oiaa


3/19/04 10:30 AM - PHYSICS LABORATORY SEMINAR: Lise Meitner and the discovery of Nuclear Fusion
When the discovery of nuclear fission was first reported in 1939, it appeared that the chemists Otto Hahn and Fritz Strassmann had performed the crucial experiments, while the physicists Lise Meitner and Otto Frisch provided the first theoretical explanation of the fission process. Historical accounts have tended to emphasize that divide ever since, as did the award of the Nobel Prize in chemistry to Hahn alone. But history and the published record can be deceptive, and Nobel committees can make mistakes. In this talk I will show that Meitner and nuclear physics were crucial to the discovery, but that Meitner’s role was obscured by her forced emigration, the political conditions in Nazi Germany, and the deliberate “forgetting” of the postwar period.
Ruth Lewin-Sime , Author and Science Historian.
Administration Bldg, Green Auditorium. (NIST Contact: Flo Parkhill, 301-975-4203, florence.parkhill@nist.gov)
Special Assistance Available


3/26/04 10:30 AM - INTELLIGENT SYSTEMS DIVISION SEMINAR: Expectation-based, Multi-focal, Saccadic (EMS-) Vision for Perception and Control of Vehicle Motion
Over the last six years (1997 – 2003), building on two decades of experience with two generations of vision systems based on the 4-D approach to dynamic vision, the vertebrate-type EMS-vision system has been conceived, built and validated experimentally. The latest results with the two experimental vehicles VaMoRs (a 5-ton van) and VaMP (a sedan Mercedes 500 SEL) will be discussed. A new level of active gaze control and the explicit representation of behavioral capabilities allow great flexibility and adaptability. The intermediate level of dynamic knowledge representation nicely separates systems dynamics methods (exploiting large data streams from sensing) from AI-methods with predominantly quasi-static knowledge components (for mission planning, situation assessment and behavior decision). Behavioral capabilities are represented on both levels with correspondingly adapted interface parameters and methods. Results will be shown by video for combined radar/vision-based hybrid adaptive cruise control (keeping speed-dependent distance to the vehicle in front) on highways (VaMP) and for mission performance on a network of minor unmarked roads, and cross-country-driving on grass surfaces with avoidance of negative obstacles (ditches). In the last-mentioned application (maybe for the first time) full frame-rate, full image stereo interpretation in this complex environment has been achieved integrating special US-hardware (Pyramid Vision Technology ‘Acadia’) into the distributed COTS-PC-system used for EMS-vision.
Ernst Dickmanns , Prof. Dr. -Ing Universitaet der Bundeswehr, Munich (UBM), Munich, Germany, ld1beddi@UniBw-Muenchen.de.
Bldg 304 (Shops Conf. Room), Rm. B126. (NIST Contact: Craig Schlenoff, 301-975-3456, craig.schlenoff@nist.gov)



MEETINGS ELSEWHERE



3/8 -- MONDAY

No Scheduled Events

3/9 -- TUESDAY

4:15 PM - THE JOHNS HOPKINS UNIV. CHEMISTRY COLLOQUIUM: FUNDAMENTAL STUDIES OF HETEROGENEOUS ENVIRONMENTAL CHEMISTRY: NOX REDUCTION USING METAL OXIDES
C. Friend , Harvard Univ..
Bldg, Rm. .
Rm. 233, Remsen Hall, The JHU, Baltimore, MD. (NIST Contact: R. Elder, 410-516-7432, -)


12:15 PM - THE JOHNS HOPKINS UNIV. CHEMISTRY COLLOQUIUM: OXIDATIONS OF C-H AND O-H BONDS BY METAL COMPLEXES: PROTON-COUPLED ELECTRON TRANSFER AND MARCUS THEORY
J. Mayer , Univ. of Washington.
Bldg, Rm. .
Rm. 233, Remsen Hall, The JHU, Baltimore, MD. (NIST Contact: R. Elder, 410-516-7432, -)




3/10 -- WEDNESDAY

No Scheduled Events

3/11 -- THURSDAY

No Scheduled Events

3/12 -- FRIDAY

No Scheduled Events

ADVANCE NOTICE

3/20/04 7:30 AM - CAPITAL SCIENCE 2004
. . , ..
Bldg, Rm. .
Conference Center, National Science Foundation, Arlington, VA. (NIST Contact: Peg Kay, 703-536-0990, pk@vertchnic.com) http://www.washacadsci.org/Wesbite/index.htm




TALKS BY NIST PERSONNEL


CHAKA, A. : HOW SCIENTIFIC COMPUTING, KNOWLEDGE MANAGEMENT, AND DATABASES CAN ENABLE ADVANCES AND NEW INSIGHTS IN CHEMICAL TECHNOLOGY.
Brock Institute for Scientific Computing, Brock University, St. Catharines, Canada, 2/2.

CHAKA, A. : HOW SCIENTIFIC COMPUTING, KNOWLEDGE MANAGEMENT, AND DATABASES CAN ENABLE ADVANCES AND NEW INSIGHTS IN CHEMICAL TECHNOLOGY.
Chemistry Department, University of Toronto, Toronto, Canada, 2/3.

ROBEY, S. : ELECTRONIC STRUCTURE AND FERMI LEVEL ALIGNMENT IN PHENYLENE ETHYNYLENE SELF -ASSEMBLED MONOLAYERS.
Rutgers University, New Brunswick, New Jersey, 3/4.

ROBEY, S. : ELECTRONIC STRUCTURE AND FERMI LEVEL ALIGNMENT IN PHENYLENE ETHYNYLENE SELF -ASSEMBLED MONOLAYERS.
Princeton University, Princeton, New Jersey, 3/5.

WALLACE, W. : QUANTITATIVE POLYMER MASS SPECTROMETRY.
Pittcon Meeting, Chicago, IL, 3/8.

GUTTMAN, C. : ISSUES IN USE OF MALDI MS TO CERTIFY MOLECULAR MASS OF SYNTHETIC POLYMERS.
PITTCON 2004, Chicago, IL, 3/8.

DEROSE, P. : PORTABLE FLUOROMETER STANDARDS AND PERFORMANCE FOR BIOAGENT DETECTION AND POINT-OF-CARE APPLICATIONS.
Pittsburgh Conference 2004, Chicago, IL, 3/8.

BYRD, H. : MALDI-TOF MS OF END-FUNCTIONALIZED POLYMERS.
PITTCON 2004, Chicago, IL, 3/9.

CHAKA, A. : AB INITIO THERMODYNAMICS: STRUCTURE & REACTIVITY OF METAL OXIDE SURFACES IN A REAL WORLD ENVIRONMENT.
Accelrys World 2004, San Diego, CA, 3/9.

BLACKBURN, D. : TEMPERATURE MEASUREMENTS OF SEMICONDUCTOR DEVICES - A REVIEW.
IEEE Semiconductor Temperature Measurement and Management Symposium, San Jose, CA, 3/10.

ANTONUCCI, J. : AN AMINO ANALOG OF BIS-GMA: SYNTHESIS, CHARACTERIZATION AND PRELIMINARY EVALUATION.
82nd General Session of the IADR, Honolulu, HI, 3/11.

MICHAELS, C. : CONFOCAL RAMAN IMAGING OF HETEROGENEOUS POLYMERIC MATERIALS.
PITTCON 2004, Chicago, Illinois, USA, 3/11.

HUNT, F. : MARKOV DECISION PROCESSES AND A POTENTIAL APPLICATION TO BIOLOGICAL SEQUENCE ALIGNMENT.
American Mathematical Society Meeting, Tallahassee, FL, 3/13.



ANNOUNCEMENTS


REMINDER
NIST Form 1176 is the NIST Sponsored or Co-Sponsored Meeting Approval form for meetings held on or off site. This form must be completed for meetings hosted by NIST with NIST staff heavily involved in planning meeting content and format; for small technical training courses or seminars sponsored by NIST intended primarily for technical peers outside NIST; for training courses intended primarily for non-NIST staff; or for meetings sponsored or co-sponsored by NIST with a national and international audience and speakers. NIST Form 1176A should be used for meetings hosted by NIST in which NIST has little or no involvement in the technical program or for educational or cultural activities planned by the local community. When beginning a conference planning process, please remember to complete one of the above forms and forward it to Kathy Kilmer in the Conference Program, Mail Stop 3461.
NIST Contact: Kathy Kilmer, 301-975-2858, kathy.kilmer@nist.gov


VISITOR REGISTRATION FOR NIST EVENTS
Because of heightened security at the NIST Gaithersburg site, members of the public who wish to attend meetings, seminars, lectures, etc. must first register in advance. For more information please call or e-mail the "NIST contact" for the particular event you would like to attend.
NIST Contact: . ., ., .


UPDATE OF NRC/NIST POSTDOCTORAL RESEARCH ASSOCIATESHIPS PROGRAM BOOK FOR 2005 AND CALL FOR ADVISER NOMINATIONS
Attention NIST postdoctoral research advisers and researchers, your laboratory offices are in the process of updating the NRC/NIST Postdoctoral Research Associateships Program Book for 2005 (deadline April 21, 2004). Please send your revised and/or new research opportunities in Rich Text Format, through your division, to your laboratory coordinators: Sheilda Bryner, EEEL; Lani Glover, MEL; Tia Crawford, CSTL; Flo Parkhill, PL; Jim Kelly, MSEL; Gail Crum, BFRL; Liz Lennon, ITL. NIST researchers who are not currently advisers are welcome to apply at this time or any time during the year. However, if applying to be an adviser by the April 21st deadline, please forward your nomination through your division, to your laboratory coordinator. To obtain a copy of the adviser nomination form, download the form at: http://www.national-academies.org/rap.
NIST Contact: Janice Campbell, 301-975-3076, janice.campbell@nist.gov


ATTENTION NIST RESEARCHERS: HOW TO BECOME AN NRC POSTDOC RESEARCH ADVISER
NIST needs researchers who are interested in becoming NRC/NIST postdoc advisers. Nominations are currently due April 21, 2004, coinciding with the annual update of the NRC/NIST Postdoctoral Research Associateships Program Book for 2005. Please forward NRC postdoc adviser nominations through your division, to your laboratory book coordinator: Sheilda Bryner, EEEL; Lani Glover, MEL; Tia Crawford, CSTL; Flo Parkhill, PL; Jim Kelly, MSEL; Gail Crum, BFRL; Liz Lennon, ITL. The nomination form may be downloaded at: http://www.national-academies.org/rap. Please contact Dr. Jack Hsia, Office of International and Academic Affairs (Division 109), (301)975-3067, jack.hsia@nist.gov, to inquire about this worthy opportunity to help attract NRC applicants to NIST.
NIST Contact: Janice Campbell, 301-975-3076, janice.campbell@nist.gov




NIST WEB SITE ANNOUNCEMENTS


NIST/NRC POSTDOCTORAL RESEARCH ASSOCIATESHIPS INFO ON OIAA INTERNAL WEB SITE
Do you know, that on the Office of International and Academic Affairs (OIAA) internal web site: http://www-i.nist.gov/oiaa/oiaa_int.htm, information concerning the National Research Council (NRC) Postdoctoral Research Associateships Program at NIST may be found. Highlights include: Official Documents Relating to Program, Brief History of Program, Statistics of Awards to Women, Statistics of Applicants and Awards Feel free to contact Dr. Jack Hsia, NIST Program Representative, should you want to discuss any of the information that is posted on the web site, (301)975-3067, or e-mail, jack.hsia@nist.gov.
NIST Contact: Janice Campbell, 301-975-3076, janice.campbell@nist.gov


NIST OUTREACH TO MINORITY SERVING INSTITUTIONS - INFO ON OIAA INTERNAL WEB SITE
Please be aware, the Office of International and Academic Affairs (OIAA) internal web site: http://www-i.nist.gov/oiaa/oiaa_int.htm, contains information concerning the "Status of Outreach to Minority Serving Institutions (MSI) by NIST Staff, FY00-FY03." Feel free to contact Dr. Jack Hsia, OIAA (Div. 109), should you want to discuss any of the information that is posted on the web site, (301)975-3067, or e-mail, jack.hsia@nist.gov.
NIST Contact: Janice Campbell, 301-975-3076, janice.campbell@nist.gov


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