[Action of sodium sulfachlorpyrazine (ESB3) on the endogenous development of Eimeria tenella in the experimental infestation of chickens]

Studies were carried out on the action of sulfachlorpyrisine-Na (ESB3) on the endogenic development of Eimeria tenella in the case of experimental infection in birds. Most sensitive to the preparation were the endogenic forms between the 48 h and the 72 nd following the act of infection. Given to birds on the day of infection and 24 hours later it produced no harmful effect on the further endogenic development of E. tenella. When the preparation was applied at the 72 nd hour it led to the degeneration of most of the II generation schizonts and inhibited their further development. As a result no oocysts were found in the feces of birds up to the 10 th-11 th day after infection. When applied at the 92 nd and the 120 th hour sulfachlorpyrisine-Na interfered with the development of the already finite forms of gametogony without concurrent degenerative effects.

PMID: 6659349 [PubMed - indexed for MEDLINE]