Your Excellency, Mr. Chancellor, Ladies and Gentlemen: I shall avoid a common practice of speakers, namely to begfn so far away from the subject that their hearers, more newly captive than captivated, sit in strained bewilderment, which the speaker misin- terprets as interest, though actually they are wafting for some season- able clue as to what he has chosen as the subject of his talk, I am go- ing to talk of institutes in the field of medicine: not of thls Insti- tute but rather more broadly and generically of medical institutes, their nature, purposes, and component parts, Having thus advised you of my direction and destination these remarks will now admittedly begfn at some distance from the subject, the better to locate it in the matrix of the facts that make the kind of human associations we call uDu.tues, important now and for the morrow of Medicine. By a notable if not, indeed, a very remarkable quality of hu- man intelligence we are at times able to guess that some statement, is probably important even when we cannot honestly say we fully understand it. My younger years were studded with experiences of this sort, often elusive, sometimes incomprehensible, but nearly always memorable. Con- sequently I came to relish SwedenborgOs definition of revelation as clouding over or obscuring of Divine Truthofv to be dismissed with the easy apostrophe of 'sfmportant if true.'? Such experiences were not They 2 were more arresting than that, for they deserved the comment "important if understandable Now among such revelations - in the Swedenborgian sense - that I remember vividly was a remark made at Oxford to my chief Dr. Richard M. Pearce. I cannot trust my memory but 1 think it was Sherrington who made it. It ran fn this wise: "After some hundreds of years of experience we think we have learned here in Oxford how to teach what is known. But now with the undenfable upsurge of scientific research, we cannot continue to rely on the mere fact that we have learned how to teach what is known. We must learn how to teach the best attitude to what is not yet known. we cannot escape this new challenge - nor do we want to." This also may take centuries to acquire but I knew at the time that that statement was important but I also knew that it would take me time to understand it, It has, Even after some thirty years I cannot be sure I understand all its implfcations. For example, it is profitable to regard an institute in one of the clini- 7J-L cal branches of medicine as the right way to teach the best attitude to what is not yet known? Is learning the rfght attitude to the unknown the vital core of this new form of association we call an instftute? I thfik it probably is. But even more probable, I think it is wise to reflect on what institutes are, suspending final decision until we see the matter as a whole. I wonder, for example, whether the research method will not transform the structure, the methods and the purpose of all of university education in, say, the next five decades. And what of secondary education? Indeed will education as a whole not be profoundly changed? Is an insti- tute the forerunner and the prototype of higher education in the fu-bure? 3 For still another reason some increased reflection upon what we call institutes may be needed today and fn the future. institutions must reckon with two forces. represents a sort of parallelogram of forces. One is the inherent in- tent to supply stability of purpose and effort, the other is to be promptly and delicately responsive to changes in the environment and even changes in objectives. The French economist Francis Delaisi had an interesting interpretation of institutions: was to supply the stability needed for long-term operations. long-term operation of raising a family we have the institution of mar- riage. real property, land tenure etc., so that he who ploughs may reap. For manufacture and commerce we have banks. For education we have schools and universities. with which institutions supply stability for human effort that he came to regard stability no longer as a mere characteristic of institutions but rather as the essential purpose of instftutions - namely to provide the stability that men and women of tenacious purpose require for bring- ing long-term operations to a successful end, All human Their resulting conduct their purpose, he held, For the For the raising of crops we have the various institutions of Indeed Delaisi was so impressec? by the constancy And yet we cannot safely exalt our need for stability and con- tinuity to be the end-all and be-all. of an institution. We must needs adjust the institution to change - or see it perish of its own brittle- ness. It was Bertrand Russell I belleve who suggested a new and impish form of conjugating vari- ous verbs: "1 am firm, you are insistent, he is pigheaded" or "1 think, you cerebrate, he theorizesrr or am open-minded, you are uncertain, he . Who can deny that stability can be pushed too far? 4 is positively schizofdOtf Obviously even excellent resolves and poli- cies can be pushed too far - there comes a time when it is reasonable to dispense with reasons. Even certainty, stability and determination have their proper limits. As Oscar Wilde observed When you break the little laws the big laws begin to operateQrv And so with human institutions: stability must reckon with adjustability if we are to be concerned with survival. stitutions, and a fortiori institutes, maintain a precarious balance between opposing forces; tenacity in the face of adaptability, sta- bility risking extinction in a world forever changing. Nearly all in- If the very survival of human associations depends upon the skill with which they steer between the Scylla of senseless rigidity and the Charybdis of unpredictably erratic changefulness, then what is the wise cowse in these singularly changeful tfmes in which we live? For clearly we live at a time when the circumstances of daily life are changing more rapidly than they have ever changed fn man's experience. As Elton Mayo insfsted ours is an adaptive not a traditional civiliza- tion. What tradition could we consult to guide our conduct in point of atomic bombs, Jet planes, and television, antfbfotfcs, ACTH, artificial insemination and even artificial rainstorm? the Hippocratic Oath for the problems of birth control? mention even of Preventive Medicine in that Oath. What guidance is there in There is no For these reasons and theilp cumulative impact on our tradi- tional forms of living and working together, I would insist that we would be wise to hold our medical institutes up to careful review - not because I suspect there is something wrong about them, but because it Is so 5 important to know exactly what is right about them, and thus what we can count on. sible about what you want most of all, because sooner or later you are so likely to obtain it. Goethe held that it is important to know as much as pos- Medical institutes generically have for me two leading char- acteristics, one that of a deliberate independent identity and the other that of something initiated or originated for a new and specific purpose. The words "task force1I connote an ad hoc specified focus of attention and energy. become a cliche', that an institute is an institutionalized task force. Now the advantages of having a declared and recognized sepa- One might say, if the new phrase has not already rate status for an institute fi a university depend in large measure on the way in which it articulates with other members of the body corporate. I like my arms to have separate parts articulating with each other by means of strong, supple and painless Joints, though of course complete rigidity from shoulder to finger tips might appeal to the administra- tive principles of uniformity, simplicfty of control and predictability of behavior. painlessly, freely and yet tightly works far more effectively than a single rigid unit. Everything depends on the quality of the joints. By the same token the character of an institute's articulations with other members of the university decides whether you will be partners in a beautifully supple and adroit instrument, or contributors to acute rheumatic inflammation or a chronic anchylosing arthropathy - in simpler terms and fewer syllables - a flail instead of an arm. Clearly an arm with several separate units articulating There are other reasons for an institute to have recognizable identity. Separate status provides a focal point not only for the loyal 6 energies of its members but also for the interest of its actual and potential supporters. Human loyalty seeks vfsible, tangible objects of manageable proportions .... need I expatiate on the theme of loyalty to the clan of Scots descendants in Montreal? Sir James Barrie acting as toastmaster at a dinner in London on St. Andrew's Night opened with the remark "1 have always thought that it was right and proper for the Scots resident in London to assemble at least once a year and examine that grave question: is there any defect in the Scot's character?If Though apparently a purely rhetorical question it could perhaps have well been answered by another question (for Charles Lamb says that a Scotsman fflives fn a twilight of dubiety"), namely Ifis there not a limit to the extent to which clannish loyalty can wisely goff? Besides serving the purpose of stability and continuity both of effort and of the best circumstances for effort, an institute can help to stimulate as well as to reassure its members. By the very self-imposed circumscription of its size and ambit an institute can provide an extraordinary aid to human effort and satisfaction - namely the chance to be intimate with excellence. Whether we invoke memory, or bear witness to our present and immediate experience, who of us will set a trivial value upon intimacy with excellence? If that in- timacy be sacrificed, whether because of increased size or excessive busyness, then the members of any institute can look at each other in just if iable dismay. Granted that an fistitute articulates smoothly and well with other parts of the university and that its members are loyal and de- voted, and that its size and activity actually permit, as well as 7 theoretically encourage, excellence to be attained and be felt, there is one more purpose an institute must serve, differentiation of function and a division of labor amongst its mem- bers, but there should be an air of expectancy among them: not merely that each will do his expected task well but that in some way not yet clear each will bring to the work of the institute some- thing distinctly and peculiarly his own, and at his own good time will add something unique to what may be expected of one in his position. division of labor that is not accompanied by the enhancement of personal dignity and individuality offers no permanent solution to the difficul- ties of collaborative work. My phrase Pthe atmosphere of expectancy' refers to the value of realizing that men can be more than the positions they occupy, and that in medicine, as fn art, there remains for each of us the problem of style. This shows in a comment I remember about Dr. Rea here in McGI11. But it was the That kfnd of comment is healthy and it is bracing. The members of Institutes cannot be wasting time when they brood upon the problem of style - for both teaching and research are ways of life. Not only must there be a expectancy A "It wasn't merely that he was a good teacher: he was. he taught and lived," The greatest and deepest need of a medical institute is to be needed. organization came quite sfmply from the fact that it met a cogent and widely recognized need. Indeed the kudos and honor of some emergency organizations, once their task is done, becomes so extraordinary that mere membership becomes a much sought after honor - in short the organi- zation becomes honorific and no longer meets any need more urgent than that of ambitfous vanity. The hedfate and the long-remembered success of many an gd hoc 8 Now there are needs that are recognized and there are needs To create an institute to meet a need that is that are unrecognized. widely felt and already formulated requires no mean abilities: to institute an organization to meet a need not yet perceived by most men calls for quite exceptional talents. But the cardinal question must always remain - is there a real need? Furthermore there is a delicate question nearly always of great practical importance, the question of timing, for it is quite possible to organize an institute so long before the need it will meet is generally recognized that sup- port for the institute cannot be found in time to save it. As one who has had thirty years' experience, both direct and vicarious, with widely different forms of financial support to insti- tutes and departments of medicine and surgery and various special fields, I believe that endowment - whether from government or private sources - is the soundest way to secure optimum results when it is certain the work to be done is needed. The steady confidence that is conferred by endowment calls out from scientists honesty and steadfastness of purpose: the hesitant uncertainty of short-term grants all but insults the Intel- ligence if not the sincerity of the recipient and certainly makes a mockery of long-term planning. Indeed it cannot be news to some of you that a reaction has set in against short-term grants. They dissuade the more honest and circumspect young men from entering investigative careers. for two years may be needed for some urgent problem income from that sum, $4,500, as dependable: ment. Experience is our teacher In this matter. They have favored hasty work on trivial questions. Though there are occasions when $50,000 a year I would prefer the that is my considered judg- 9 You will notice that till now I have not referred to the leader of an institute but only to the members. at 24 or even younger took command of whalfng ships as captains, have gone. years gave comparably early responsibility to young men in academic life. But as the preparatory stages become longer and the candidates more numerous we may expect to see more rarely the load of leadership of institutes falling on men when they are really young. Perhaps the only thing I find myself wanting to say to most new leaders of insti- tutes is this: pected. As a corrective you may do well to find someone not on the payroll, a man of perfect discretion and considerable detachment with whom you can discuss your problems with complete freedom and confidence. Indeed there is some evidence suggesting that some of the most success- ful leaders of medical institutes took counsel quietly and steadily with one or two advisers. Certainly Shon Flexner relied on William H. Welch in that way. Now the days when men Perhags the earlier frontier universities of the past hundred you'll find the task a little lonelier than you ex= The best leaders of scientific institutes whom I have known had only this in common: out the organization, an institute seemed to rewad so wide a variety of temperaments, capaci- ties and characters. There didnPt seem to be any one formula to explain the leader's role. At long last I came to see that what a leader trans- mits is the quality and the variety of his values, for he is quick to recognize and encourage in others those qualities, purposes and interests that seem most significant to hh, they made their values known and felt through- I used to be puzzled that success as the head of 10 One other aspect of leadership in a scientific institute re- lates to the number of men on its staff. If we are to take seriously the opinion of students of admfnistration we should be critical of the leader who has more than eight men reporting to him. vary in point of the number of colleagues with whom they can work ef- fectively, to whose work they can bring discriminatfng and helpful en- couragement and criticism, and of whose lives they can be effectively informed. Eight may not always be the maximum, but of one thing I am sure: as the technology of travel and communication has become quick, cheap and easy to initiate, No sooner did we put in fnter-office telephones than staff lunch or tearooms became necessary. the lymphatic system, the circulatory system and the nervous system each devoted to some form of transport, communication and coordination, we may well suspect that the factor to pay most attention to in deciding the size of an institute fs not the possible work to be done, nor the number of possible subdepartments, nor the size of its budget, nor the number of candidates for staff positions, nor the size of similar in- stitutions elsewhere, but somethfng more stark and searching - the quality of communications between its members, their clhity, brevity, completeness, promptness, and sincerity. That is what makes an Insti- tute Doubtless leaders the capacity to work with others has not Increased as rapidly When the body possesses Directly related to the most desbable size of an institute and also of capital importance to the future, stands the subject of re- cruitment, like now merely to submit for your consideration a new word and the Rather than attempt to review many of its aspects I would 11 need I feel for it, The word is decruitment, Recruitment comes from the French re-croitre to grow again. It has not quite the same meaning as increase but rather the idea of replacement of expected losses. But in some of the best institutes IDve known nobody wants to leave. is needed is a decruitment policy, as clear and automatic and impartial as can be, with this new specific word decruitment as impersonal as a uniform and without any overtones of disapproval, failure or disappoint- ment. after a stipulated period of two or perhaps four years and those that are wanted back can be called back after a lapse of not less than a year. Like retirement policies whose application becomes more invidious with every fnfractfon, recruftment without my policy of decruitment seems insincere. Indeed it seems ominous,, It suggests to me one of the common characteristics of cancer cells - they lack self-control. So I commend to you a new word - decruitment - to draw attention to what is needed in place of the shoddy euphemism "he was let go," as though he was straining at the leash and choking for departure - which he was not, and everyone knew it, What The policy of decruitment means that all recruits ought to leave We can have something cleaner than that, Having referred to institutes in terms of their purposes and the role of membership, leadership, size and ways of self-renewal, I come to the sub6ject of trustees or other forms of control and supervision. Here, too, rather than try to cover the subject, I would underscore one aspect of trusteeship that deserves more attention than it seems to re- ceive, There are not enough Trustees who brood over the affairs of our institutes. do not have in m-fnd. Now blooding as a word may connote to some of you meanhgs I I do not mean by brooding fussy and officious 12 interference, nor gloomy preoccupation wfth problems that ?a" t he briskly solved, nor plausible arguments that the ship is sinking and should be scuttled in favor of some coracle made of balsa wood,, No, By brooding I mean first a thorough working knowledge of the insti- tute's affairs and then what Its problems are, what we the unseen needs it could be meeting, what is dubfous and what is certain in its future, and especially whether in objective, as well as in performance, the institute is striking the right balance be-bween stability and ad- justability, between unflinching adherence to ex-lstfig purposes and a suppleness of adaptation to a constantly chmging world of knowledge and of need. against what could be, the steady, quiet evaluation of the potentialf- ties as well as the actualities of the institute. A good brooder is at home in the subjunctive, in the language of" unreality, for the future almost by definition is not yet real, By brooding I mean the constant weighing of what & Using such criteria we come to face the undeniable fact that the quality of trusteeship in ow institutes deserves itself some brood- ing. Too vague, perhaps, too general and too inclusive. So let me close in a contrasting vein of specific, local and exclusively historical fact, Indeed brooding has been the key in which this talk is written, En but very few if any of the enterprises to which The Rocke- feller Foundation has been privileged to contribute in the last twenty years have the results equalled those you have created here in this Neurologfcal Institute, the Medical Sckaces Division of the Foundation has made since 1931 that I consider ideal fn purpose9 in performance, fi local response If I weye asked to name a single grant that 13 and in national and international influence, and In the character of our relationships maintained from the very beginning, I would say without a moment's hesitation the grant to the Neurological Institute of McGill University. But that is only one way and perhaps a trivial one of expressing the admiration and the satisfaction The Rockefeller Foundation has for what you have created here. compliment I would offer you, not without some fear that it will fail its target, in saying that in this Neurological Institute, the Staff, the Chief and the Trustees are so beautifully fused Into one shining amalgam that if I were to name one to thank I: would be naming you all who have worked with him, for him and through him, and if I were to name all of you it would come to the same thing - for you are all the Neurological Institute of McGill University, each to the other, re- sponsible, essential and inseparable. More rare still is the (signed) Alan Gregg