| Infect Immun. 1997 April; 65(4): 1505–1509. | PMCID: PMC175159 |
African strains of Blastomyces dermatitidis that do not express surface adhesin WI-1. B S Klein, B D Aizenstein, and L H Hogan Department of Pediatrics, University of Wisconsin Medical School, Madison 53792, USA. Abstract African strains of Blastomyces dermatitidis differ from North American strains in their growth, morphology, and clinical disease phenotype. In addition, two serotypes, designated 1 and 2, have been described. We investigated African strains of B. dermatitidis for expression of the surface protein adhesin WI-1 and found that serotype 2 strains do not express it because they lack the coding sequence in their genome. The defect will make the strains useful for gene complementation and for testing the pathogenetic role of the WI-1 adhesin. Full Text The Full Text of this article is available as a PDF (224K). These references are in PubMed. This may not be the complete list of references from this article. - Bradsher, RW. Systemic fungal infections: diagnosis and treatment. I. Blastomycosis. Infect Dis Clin North Am. 1988 Dec;2(4):877–898. [PubMed]
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