From pjrhusbands at lbl.gov Mon Jul 23 16:37:16 2007 From: pjrhusbands at lbl.gov (Parry Husbands) Date: Mon Jul 23 16:38:52 2007 Subject: [BANANA] Berkeley Lab - Scientific Computing Seminar - Thursday, July 26, 2007 Message-ID: Date: Thursday, July 26, 2007 Time: 11:00am-12:00pm Location: Building 50A-5132 Seminar Speaker: Heng Huang Department of Computer Science and Engineering University of Texas at Arlington http://ranger.uta.edu/~heng/ Title: Shape Modeling and Alignment: Applications to Biomedical Informatics Abstract: Shape modeling and surface representation combine physical measurement of objects with mathematical models and are important in a large number of scientific and engineering areas. Biomedical informatics is one of the most important applications. In this talk, I will present two recent results on shape modeling and registration with several applications in biomedical informatics. In the first part, I will show a novel surface registration algorithm for arbitrarily shaped but simply connected (i.e., contiguous) 3D objects. Based on the rotational properties of harmonic analysis, a new Parameterization Rotation Theorem is introduced and proved and a fast surface alignment algorithm is developed. This algorithm can accurately and efficiently generate surface correspondences between objects for which spherical harmonics (SPHARM) was used for surface modeling. Its computational complexity is improved from the O(n^3) of previous methods to O(n^2). These techniques have been applied to many biomedical applications, including improving morphological understanding of anatomic structures, dynamic shape analysis (e.g. of beating hearts), cardiac electromechanical model, protein-protein docking, and assisting in medical tasks like pacemaker placement. In the second part, I will present a new hemisphere-based harmonic surface model. I define a set of complete hemispherical harmonic basis functions on a hemisphere domain and use these to support a novel parametric shape description method. This method is very useful in efficiently and flexibly representing the surfaces of certain anatomical structures (like heart ventricles) in biomedical applications. Heng Huang received his Ph.D. degree in Computer Science at Dartmouth College in 2006. Before he joined University of Texas at Arlington (UTA), he worked as a postdoctoral researcher at the Center for Biological and Biomedical Computing in the Biology department at Dartmouth College. Currently he is an assistant professor in the computer science and engineering department at UTA and leads the BIOVIZON (biomedical computing and visualization) Lab, where his research focus is on the areas of biomedical image analysis, bioinformatics, pattern recognition, and scientific visualization. Sponsor of Seminar: Chris Ding