page198
Oral
Salbutamol
(Non-proprietary) A
Tablets
,
salbutamol (as sulphate) 2 mg,
net price 28-
tab pack = £17.74;
4 mg,
28-tab pack = £16.40
Oral solution
,
salbutamol (as sulphate) 2 mg/5 mL,
net price 150 mL = £1.55
Brands include
Salapin
c
(sugar-free)
Ventmax
c
SR
(Chiesi) A
Capsules
, m/r, salbutamol (as sulphate) 4 mg (green/
grey), net price 56-cap pack = £8.08; 8 mg (white), 56-
cap pack = £9.69.
Label:
25
Dose
8 mg twice daily;
CHILD 3–12 years 4 mg twice daily
Ventolin
c
(A&H) A
Syrup
,
sugar-free,
salbutamol (as sulphate) 2 mg/
5 mL,
net price 150 mL = 60p
Parenteral
Ventolin
c
(A&H) A
Injection
,
salbutamol (as sulphate) 500 micrograms/
mL,
net price 1-mL amp = 38p
Solution for intravenous infusion
,
salbutamol (as
sulphate) 1 mg/mL. Dilute before use. Net price 5-mL
amp = £2.48
Inhalation
Counselling
Advise patients not to exceed prescribed dose
and to follow manufacturer’s directions; if a previously
effective dose of inhaled salbutamol fails to provide at least 3
hours relief, a doctor’s advice should be obtained as soon as
possible.
Salbutamol
(Non-proprietary) A
Aerosol inhalation
,
salbutamol (as sulphate)
100 micrograms/metered inhalation,
net price 200-
dose unit = £3.19.
Counselling,
administration
Brands include
Salamol
c
,
Salbumalin
c
Dry powder for inhalation
,
salbutamol 100 micr-
ograms/metered inhalation, net price 200-dose unit =
£3.31;
200 micrograms/metered inhalation,
100-dose
unit = £4.85,
200-dose unit = £6.63.
Counselling,
administration
Brands include
Easyhaler
c
Salbutamol
,
Pulvinal
c
Salbutamol
Inhalation powder
, hard capsule
(for use with
Cyclohaler
c
device), salbutamol 200 micrograms, net
price 120-cap pack = £8.99; 400 micrograms, 120-cap
pack = £12.99.
Counselling,
administration
Brands include
Salbutamol Cyclocaps
c
Nebuliser solution
,
salbutamol (as sulphate) 1 mg/
mL, net price 20 2.5 mL (2.5 mg) = £1.91; 2 mg/mL,
20 2.5 mL (5 mg) = £3.82.
May be diluted with
sterile sodium chloride 0.9%
Brands include
Salamol Steri-Neb
c
Airomir
c
(IVAX) A
Aerosol inhalation
,
salbutamol (as sulphate)
100 micrograms/metered inhalation,
net price 200-
dose unit = £1.97.
Counselling,
administration
Autohaler
(breath-actuated aerosol inhalation),
sal-
butamol (as sulphate) 100 micrograms/metered
inhalation,
net price 200-dose unit = £6.02.
Counsel-
ling,
administration
Asmasal Clickhaler
c
(UCB Pharma) A
Dry powder for inhalation
,
salbutamol (as sulphate)
95 micrograms/metered inhalation,
net price 200-
dose unit = £5.65.
Counselling,
administration
Dose
acute bronchospasm,
by inhalation of powder,
ADULT and
CHILD over 5 years,
1–2 puffs;
for persistent symptoms up to 4
times daily (but see also Management of Chronic Asthma table,
p.
172)
Prophylaxis of allergen- or exercise-induced bronchospasm,
by
inhalation of powder
,
ADULT and CHILD over 5 years, 1–2 puffs
Salamol Easi-Breathe
c
(IVAX) A
Aerosol inhalation
,
salbutamol 100 micrograms/
metered inhalation,
net price 200-dose breath-actu-
ated unit = £6.30.
Counselling,
administration
Salbulin Novolizer
c
(Meda) A
Dry powder for inhalation
,
salbutamol (as sulphate)
100 micrograms/metered inhalation,
net price refill-
able 200-dose unit = £4.95;
200-dose refill = £2.75.
Counselling,
administration
Dose
acute bronchospasm, by inhalation of powder, ADULT 100–
200 micrograms;
for persistent symptoms up to 800 micrograms
daily (but see also Management of Chronic Asthma table, p.
172);
CHILD 6–12 years 100–200 micrograms;
for persistent symptoms
up to 400 micrograms daily (but see also Management of Chronic
Asthma table,
p.
172)
Prophylaxis of allergen- or exercise-induced bronchospasm,
by
inhalation of powder
,
ADULT 200 micrograms;
CHILD 6–12 years
100–200 micrograms
Ventolin
c
(A&H) A
Accuhaler
c
(dry powder for inhalation),
disk con-
taining 60 blisters of salbutamol (as sulphate)
200 micrograms/blister with
Accuhaler
c
device,
net
price = £4.92.
Counselling,
administration
Dose
acute bronchospasm,
by inhalation of powder,
ADULT and
CHILD over 5 years, 200 micrograms; for persistent symptoms up
to 4 times daily (but see also Management of Chronic Asthma
table, p.
172)
Prophylaxis of allergen- or exercise-induced bronchospasm,
by
inhalation of powder
,
ADULT and CHILD over 5 years, 200 micr-
ograms
Evohaler
c
(aerosol inhalation),
salbutamol (as sul-
phate) 100 micrograms/metered inhalation,
net price
200-dose unit = £1.50.
Counselling,
administration
Nebules
c
(for use with nebuliser),
salbutamol (as
sulphate) 1 mg/mL,
net price 20 2.5 mL (2.5 mg) =
£1.65;
2 mg/mL,
20 2.5 mL (5 mg) = £2.78.
May be
diluted with sterile sodium chloride 0.9% if adminis-
tration time in excess of 10 minutes is required
Respirator solution
(for use with a nebuliser or
ventilator),
salbutamol (as sulphate) 5 mg/mL,
net
price 20 mL = £2.18 (hosp. only). May be diluted with
sterile sodium chloride 0.9%
Compound preparations
For compound preparations containing salbutamol,
see section 3.1.4
Management of Chronic Asthma table, see p.
172
Management of Acute Asthma table, see p.
173
SALMETEROL
Indications
reversible airways obstruction (including
nocturnal asthma and prevention of exercise-induced
bronchospasm) in patients requiring long-term regu-
lar bronchodilator therapy,
see also Management of
Chronic Asthma table,
p.
172;
chronic obstructive
pulmonary disease
Note
Not for immediate relief of
acute asthma attacks;
for
use in asthma only in patients who regularly use an inhaled
corticosteroid,
see notes above
Cautions
see notes above
Pregnancy
see p.
170
Breast-feeding
see p.
170
Side-effects
see notes above;
nausea,
dizziness,
arthralgia, and rash also reported
Dose
. By inhalation,
asthma,
50 micrograms (2 puffs or 1
blister) twice daily; up to 100 micrograms (4 puffs or 2
blisters) twice daily in more severe airways obstruc-
178
3.1.1 Adrenoceptor agonists
BNF 61
3
Respiratory system